13,510 results on '"Malaspina A."'
Search Results
2. Diverse dust populations in the near-Sun environment characterized by PSP/IS$\odot$IS
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Shen, M. M., Szalay, J. R., Pokorný, P., Mitchell, J. G., Hill, M. E., Mitchell, D. G., McComas, D. J., Christian, E. R., Cohen, C. M. S., Schwadron, N. A., Bale, S. D., and Malaspina, D. M.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Space Physics - Abstract
The Integrated Science Investigation of the Sun (IS$\odot$IS) energetic particle instrument suite on Parker Solar Probe is dedicated to measuring energetic ions and electrons in the near-Sun environment. It includes a half-sky-viewing time-of-flight mass spectrometer (EPI-Lo) and five high-energy silicon solid-state detector-telescopes (EPI-Hi). To August 2024, eight of EPI-Lo's eighty separate telescope foils have experienced direct dust puncture events, most of which occurred inside 40 solar radii (0.19 au). These impacts represent the closest ever direct dust detections to the Sun. While there is limited information about the size/mass of each impact due to the lack of a dedicated dust instrument, we can determine the impact direction for six punctures, allowing us to partially constrain the inner zodiacal abundance. Remarkably, one of six unambiguous dust impacters was likely on a retrograde orbit, suggesting long-period cometary material may survive within 20 solar radii (0.09 au). We discuss observations in the context of improving our understanding of the inner zodiacal dust environment, highlighting multiple dust populations responsible for these events, and refining hazard assessment for near-Sun spacecraft.
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- 2024
3. On Primitive Ulrich Bundles over a few projective varieties with Picard number two
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Malaspina, Francesco
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Mathematics - Algebraic Geometry - Abstract
We introduce the notion of primitive Ulrich bundle in a smooth projective variety. We motivate this notion and give a cohomological characterization in the case of the degree $6$ flag threefold and rational normal scrolls. Finally we propose a few open problems., Comment: 11 pages. Dedicated to the memory of Gianfranco Casnati. The final version will appear on Rend. Semin. Mat., Univ. Politec. Torino
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- 2024
4. A solar rotation signature in cosmic dust: frequency analysis of dust particle impacts on the Wind spacecraft
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Baalmann, Lennart R., Hunziker, Silvan, Péronne, Arthur, Kirchner, James W., Glassmeier, Karl-Heinz, Malaspina, David M., Wilson III, Lynn B., Strähl, Christoph, Chadda, Shivank, and Sterken, Veerle J.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Physics - Space Physics - Abstract
Dust particle impacts on the Wind spacecraft were detected with its plasma wave instrument Wind/WAVES. Frequency analysis on this dust impact time series revealed spectral peaks indicative of a solar rotation signature. We investigated whether this solar rotation signature is embedded in the interplanetary or interstellar dust (ISD) and whether it is caused by co-rotating interaction regions (CIRs), by the sector structure of the interplanetary magnetic field (IMF), or by external effects. We performed frequency analysis on subsets of the data to investigate the origin of these spectral peaks, comparing segments of Wind's orbit when the spacecraft moved against or with the ISD inflow direction and comparing the time periods of the ISD focusing and defocusing phases of the solar magnetic cycle. A superposed epoch analysis of the number of dust impacts during CIRs was used to investigate the systematic effect of CIRs. Case studies of time periods with frequent or infrequent occurrences of CIRs were compared to synthetic data of dust impacts affected by CIRs. We performed similar case studies for time periods with a stable or chaotic IMF sector structure. The superposed epoch analysis was repeated for a time series of the spacecraft floating potential. Spectral peaks were found at the solar rotation period of ~27d and its harmonics at 13.5d and 9d. This solar rotation signature may affect both interplanetary and ISD. The appearance of this signature correlates with the occurrence of CIRs but not with the stability of the IMF sector structure. The CIRs cause, on average, a reduction in the number of dust impact detections. Periodic changes of the spacecraft's floating potential were found to partially counteract this reduction by enhancing the instrument's sensitivity to dust impacts; these changes of the floating potential are thus unlikely to be the cause of the solar rotation signature.
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- 2024
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5. Size distribution of small grains in the inner zodiacal cloud
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Szalay, J. R., Pokorný, P., and Malaspina, D. M.
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Astrophysics - Earth and Planetary Astrophysics ,Physics - Space Physics - Abstract
The Parker Solar Probe (PSP) spacecraft has transited the inner-most regions of the zodiacal cloud and detects impacts to the spacecraft body via its electric field instrument. Multiple dust populations have been proposed to explain the PSP dust impact rates. PSP's unique orbit allows us to identify a region where the impact rates are likely dominated by $\alpha$-meteoroids, small zodiacal grains on approximately circular, bound orbits. From the distribution of voltage signals generated by dust impacts to PSP in this region, we find the cumulative mass index for grains with radii of $\sim$0.6-1.4 $\mu$m (masses of $3\times10^{-15}$ to $3\times10^{-14}$ kg) to be $\alpha = 1.1 \pm 0.3$ from 0.1-0.25 $R_\odot$. $\alpha$ increases toward the Sun, with even smaller fragments generated closer to the Sun. The derived size distribution is steeper than previously estimated, and in contrast to expectations we find most of the dust mass resides in the smallest fragments and not in large grains inside 0.15 au. As the inner-most regions of the zodiacal cloud are likely collisionally evolved, these results place new constraints how the solar system's zodiacal cloud and by extension astrophysical debris disks are partitioned in mass.
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- 2024
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6. A discrete Consensus-Based Global Optimization Method with Noisy Objective Function
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Bellavia, Stefania and Malaspina, Greta
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Mathematics - Optimization and Control - Abstract
Consensus based optimization is a derivative-free particles-based method for the solution of global optimization problems. Several versions of the method have been proposed in the literature, and different convergence results have been proved. However, all existing results assume the objective function to be evaluated exactly at each iteration of the method. In this work, we extend the convergence analysis of a discrete-time CBO method to the case where only a noisy stochastic estimator of the objective function can be computed at a given point. In particular we prove that under suitable assumptions on the oracle's noise, the expected value of the mean squared distance of the particles from the solution can be made arbitrarily small in a finite number of iterations. Numerical experiments showing the impact of noise are also given.
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- 2024
7. Normative Diffusion Autoencoders: Application to Amyotrophic Lateral Sclerosis
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Ijishakin, Ayodeji, Hadjasavilou, Adamos, Abdulaal, Ahmed, Montana-Brown, Nina, Townend, Florence, Spinelli, Edoardo, Fillipi, Massimo, Agosta, Federica, Cole, James, and Malaspina, Andrea
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Predicting survival in Amyotrophic Lateral Sclerosis (ALS) is a challenging task. Magnetic resonance imaging (MRI) data provide in vivo insight into brain health, but the low prevalence of the condition and resultant data scarcity limit training set sizes for prediction models. Survival models are further hindered by the subtle and often highly localised profile of ALS-related neurodegeneration. Normative models present a solution as they increase statistical power by leveraging large healthy cohorts. Separately, diffusion models excel in capturing the semantics embedded within images including subtle signs of accelerated brain ageing, which may help predict survival in ALS. Here, we combine the benefits of generative and normative modelling by introducing the normative diffusion autoencoder framework. To our knowledge, this is the first use of normative modelling within a diffusion autoencoder, as well as the first application of normative modelling to ALS. Our approach outperforms generative and non-generative normative modelling benchmarks in ALS prognostication, demonstrating enhanced predictive accuracy in the context of ALS survival prediction and normative modelling in general.
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- 2024
8. Cross-scale energy transfer from fluid-scale Alfv\'en waves to kinetic-scale ion acoustic waves in the Earth's magnetopause boundary layer
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An, Xin, Artemyev, Anton, Angelopoulos, Vassilis, Liu, Terry Z., Vasko, Ivan, and Malaspina, David
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Physics - Space Physics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics - Abstract
In space plasmas, large-amplitude Alfv\'en waves can drive compressive perturbations, accelerate ion beams, and lead to plasma heating and the excitation of ion acoustic waves at kinetic scales. This energy channelling from fluid to kinetic scales represents a complementary path to the classical turbulent cascade. Here, we present observational and computational evidence to validate this hypothesis by simultaneously resolving the fluid-scale Alfv\'en waves, kinetic-scale ion acoustic waves, and their imprints on ion velocity distributions in the Earth's magnetopause boundary layer. We show that two coexisting compressive modes, driven by the magnetic pressure gradients of Alfv\'en waves, not only accelerate the ion tail population to the Alfv\'en velocity, but also heat the ion core population near the ion acoustic velocity and generate Debye-scale ion acoustic waves. Thus, Alfv\'en-acoustic energy channeling emerges as a viable mechanism for plasma heating near plasma boundaries where large-amplitude Alfv\'en waves are present.
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- 2024
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9. Genomics yields biological and phenotypic insights into bipolar disorder
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O’Connell, Kevin S., Koromina, Maria, van der Veen, Tracey, Boltz, Toni, David, Friederike S., Yang, Jessica Mei Kay, Lin, Keng-Han, Wang, Xin, Coleman, Jonathan R. I., Mitchell, Brittany L., McGrouther, Caroline C., Rangan, Aaditya V., Lind, Penelope A., Koch, Elise, Harder, Arvid, Parker, Nadine, Bendl, Jaroslav, Adorjan, Kristina, Agerbo, Esben, Albani, Diego, Alemany, Silvia, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F. M., Antoniou, Anastasia, Ask, Helga, Bass, Nicholas, Bauer, Michael, Beins, Eva C., Bigdeli, Tim B., Pedersen, Carsten Bøcker, Boks, Marco P., Børte, Sigrid, Bosch, Rosa, Brum, Murielle, Brumpton, Ben M., Brunkhorst-Kanaan, Nathalie, Budde, Monika, Bybjerg-Grauholm, Jonas, Byerley, William, Cabana-Domínguez, Judit, Cairns, Murray J., Carpiniello, Bernardo, Casas, Miquel, Cervantes, Pablo, Chatzinakos, Chris, Chen, Hsi-Chung, Clarence, Tereza, Clarke, Toni-Kim, Claus, Isabelle, Coombes, Brandon, Corfield, Elizabeth C., Cruceanu, Cristiana, Cuellar-Barboza, Alfredo, Czerski, Piotr M., Dafnas, Konstantinos, Dale, Anders M., Dalkner, Nina, Degenhardt, Franziska, DePaulo, J. Raymond, Djurovic, Srdjan, Drange, Ole Kristian, Escott-Price, Valentina, Fanous, Ayman H., Fellendorf, Frederike T., Ferrier, I. Nicol, Forty, Liz, Frank, Josef, Frei, Oleksandr, Freimer, Nelson B., Fullard, John F., Garnham, Julie, Gizer, Ian R., Gordon, Scott D., Gordon-Smith, Katherine, Greenwood, Tiffany A., Grove, Jakob, Guzman-Parra, José, Ha, Tae Hyon, Hahn, Tim, Haraldsson, Magnus, Hautzinger, Martin, Havdahl, Alexandra, Heilbronner, Urs, Hellgren, Dennis, Herms, Stefan, Hickie, Ian B., Hoffmann, Per, Holmans, Peter A., Huang, Ming-Chyi, Ikeda, Masashi, Jamain, Stéphane, Johnson, Jessica S., Jonsson, Lina, Kalman, Janos L., Kamatani, Yoichiro, Kennedy, James L., Kim, Euitae, Kim, Jaeyoung, Kittel-Schneider, Sarah, Knowles, James A., Kogevinas, Manolis, Kranz, Thorsten M., Krebs, Kristi, Kushner, Steven A., Lavebratt, Catharina, Lawrence, Jacob, Leber, Markus, Lee, Heon-Jeong, Liao, Calwing, Lucae, Susanne, Lundberg, Martin, MacIntyre, Donald J., Maier, Wolfgang, Maihofer, Adam X., Malaspina, Dolores, Manchia, Mirko, Maratou, Eirini, Martinsson, Lina, Mattheisen, Manuel, McGregor, Nathaniel W., McInnis, Melvin G., McKay, James D., Medeiros, Helena, Meyer-Lindenberg, Andreas, Millischer, Vincent, Morris, Derek W., Moutsatsou, Paraskevi, Mühleisen, Thomas W., O’Donovan, Claire, Olsen, Catherine M., Panagiotaropoulou, Georgia, Papiol, Sergi, Pardiñas, Antonio F., Park, Hye Youn, Perry, Amy, Pfennig, Andrea, Pisanu, Claudia, Potash, James B., Quested, Digby, Rapaport, Mark H., Regeer, Eline J., Rice, John P., Rivera, Margarita, Schulte, Eva C., Senner, Fanny, Shadrin, Alexey, Shilling, Paul D., Sigurdsson, Engilbert, Sindermann, Lisa, Sirignano, Lea, Siskind, Dan, Slaney, Claire, Sloofman, Laura G., Smeland, Olav B., Smith, Daniel J., Sobell, Janet L., Soler Artigas, Maria, Stein, Dan J., Stein, Frederike, Su, Mei-Hsin, Sung, Heejong, Świątkowska, Beata, Terao, Chikashi, Tesfaye, Markos, Tesli, Martin, Thorgeirsson, Thorgeir E., Thorp, Jackson G., Toma, Claudio, Tondo, Leonardo, Tooney, Paul A., Tsai, Shih-Jen, Tsermpini, Evangelia Eirini, Vawter, Marquis P., Vedder, Helmut, Vreeker, Annabel, Walters, James T. R., Winsvold, Bendik S., Witt, Stephanie H., Won, Hong-Hee, Ye, Robert, Young, Allan H., Zandi, Peter P., Zillich, Lea, Adolfsson, Rolf, Alda, Martin, Alfredsson, Lars, Backlund, Lena, Baune, Bernhard T., Bellivier, Frank, Bengesser, Susanne, Berrettini, Wade H., Biernacka, Joanna M., Boehnke, Michael, Børglum, Anders D., Breen, Gerome, Carr, Vaughan J., Catts, Stanley, Cichon, Sven, Corvin, Aiden, Craddock, Nicholas, Dannlowski, Udo, Dikeos, Dimitris, Etain, Bruno, Ferentinos, Panagiotis, Frye, Mark, Fullerton, Janice M., Gawlik, Micha, Gershon, Elliot S., Goes, Fernando S., Green, Melissa J., Grigoroiu-Serbanescu, Maria, Hauser, Joanna, Henskens, Frans A., Hjerling-Leffler, Jens, Hougaard, David M., Hveem, Kristian, Iwata, Nakao, Jones, Ian, Jones, Lisa A., Kahn, René S., Kelsoe, John R., Kircher, Tilo, Kirov, George, Kuo, Po-Hsiu, Landén, Mikael, Leboyer, Marion, Li, Qingqin S., Lissowska, Jolanta, Lochner, Christine, Loughland, Carmel, Luykx, Jurjen J., Martin, Nicholas G., Mathews, Carol A., Mayoral, Fermin, McElroy, Susan L., McIntosh, Andrew M., McMahon, Francis J., Medland, Sarah E., Melle, Ingrid, Milani, Lili, Mitchell, Philip B., Morken, Gunnar, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Myers, Richard M., Myung, Woojae, Neale, Benjamin M., Nievergelt, Caroline M., Nordentoft, Merete, Nöthen, Markus M., Nurnberger, John I., O’Donovan, Michael C., Oedegaard, Ketil J., Olsson, Tomas, Owen, Michael J., Paciga, Sara A., Pantelis, Christos, Pato, Carlos N., Pato, Michele T., Patrinos, George P., Pawlak, Joanna M., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Reininghaus, Eva Z., Ribasés, Marta, Rietschel, Marcella, Ripke, Stephan, Rouleau, Guy A., Roussos, Panos, Saito, Takeo, Schall, Ulrich, Schalling, Martin, Schofield, Peter R., Schulze, Thomas G., Scott, Laura J., Scott, Rodney J., Serretti, Alessandro, Smoller, Jordan W., Squassina, Alessio, Stahl, Eli A., Stefansson, Hreinn, Stefansson, Kari, Stordal, Eystein, Streit, Fabian, Sullivan, Patrick F., Turecki, Gustavo, Vaaler, Arne E., Vieta, Eduard, Vincent, John B., Waldman, Irwin D., Weickert, Cynthia S., Weickert, Thomas W., Werge, Thomas, Whiteman, David C., Zwart, John-Anker, Edenberg, Howard J., McQuillin, Andrew, Forstner, Andreas J., Mullins, Niamh, Di Florio, Arianna, Ophoff, Roel A., and Andreassen, Ole A.
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- 2025
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10. Quiescent Solar Wind Regions in the Near-Sun Environment: Properties and Radial Evolution
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Short, Benjamin, Malaspina, David M., Chasapis, Alexandros, and Verniero, Jaye L.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Physics - Space Physics - Abstract
Regions of magnetic field with near-radial, Parker Spiral-like geometry known as quiescent regions have been observed in Parker Solar Probe data. These regions have very low $\delta B / \langle |B| \rangle$ compared to non-quiescent solar wind at the same heliocentric distances. Quiescent regions are observed to have lower solar wind bulk speeds, lower proton temperatures, and lower proton density, consistent with properties of the slow solar wind. Inside of 15 Rs, identified quiescent regions show distinct thermal properties, having higher proton temperature anisotropies and lower parallel plasma betas compared to switchback patches observed at the same heliocentric distances. When placed on $\mathcal{R}$ vs $\beta_{\parallel p}$ plots (where $\mathcal{R}$ is the proton temperature anisotropy), quiescent region solar wind is shown to be more stable to proton cyclotron and firehose instabilities than non-quiescent solar wind at the same heliocentric distances. It is shown that quiescent regions evolve similarly to the surrounding non-quiescent solar wind, but quiescent solar wind begins at a different location in the $\mathcal{R}$ vs $\beta_{\parallel p}$ parameter space, suggesting that these regions have separate origins than the more turbulent non-quiescent solar wind. Namely, enhanced temperature anisotropies and enhanced magnetic field strength may be consistent with magnetic field lines which have undergone less magnetic field expansion compared to non-quiescent wind at the same heliocentric distances., Comment: 26 pages, 7 figures
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- 2024
11. Parker Solar Probe Observations of Energetic Particles in the Flank of a Coronal Mass Ejection Close to the Sun
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Schwadron, N. A., Bale, Stuart D., Bonnell, J., Case, A., Shen, M., Christian, E. R., Cohen, C. M. S., Davis, A. J., Desai, M. I., Goetz, K., Giacalone, J., Hill, M. E., Kasper, J. C., Korreck, K., Larson, D., Livi, R., Lim, T., Leske, R. A., Malandraki, O., Malaspina, D., Matthaeus, W. H., McComas, D. J., McNutt Jr., R. L., Mewaldt, R. A., Mitchell, D. G., Niehof, J. T., Pulupa, M., Pecora, Francesco, Rankin, J. S., Smith, C., Stone, E. C., Szalay, J. R., Vourlidas, A., Wiedenbeck, M. E., and Whittlesey, P.
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Space Physics - Abstract
We present an event observed by Parker Solar Probe at $\sim$0.2 au on March 2, 2022 in which imaging and \emph{in situ} measurements coincide. During this event, PSP passed through structures on the flank of a streamer blowout CME including an isolated flux tube in front of the CME, a turbulent sheath, and the CME itself. Imaging observations and \emph{in situ} helicity and principal variance signatures consistently show the presence of flux ropes internal to the CME. In both the sheath, and the CME interval, the distributions are more isotropic, the spectra are softer, and the abundance ratios of Fe/O and He/H are lower than those in the isolated flux tube, and yet elevated relative to typical plasma and SEP abundances. These signatures in the sheath and the CME indicate that both flare populations and those from the plasma are accelerated to form the observed energetic particle enhancements. In contrast, the isolated flux tube shows large streaming, hard spectra and large Fe/O and He/H ratios, indicating flare sources. Energetic particle fluxes are most enhanced within the CME interval from suprathermal through energetic particle energies ($\sim$ keV to $>10$ MeV), indicating particle acceleration, and confinement local to the closed magnetic structure. The flux-rope morphology of the CME helps to enable local modulation and trapping of energetic particles, particularly along helicity channels and other plasma boundaries. Thus, the CME acts to build-up energetic particle populations, allowing them to be fed into subsequent higher energy particle acceleration throughout the inner heliosphere where a compression or shock forms on the CME front., Comment: 41 pages, 19 figures, In Press
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- 2024
12. Selective linewidth control in a micro-resonator with a resonant interferometric coupler
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Pagano, Paula L., Borghi, Massimo, Moroni, Federica, Viola, Alice, Malaspina, Francesco, Liscidini, Marco, Bajoni, Daniele, and Galli, Matteo
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Physics - Optics - Abstract
Optical microresonators are characterized by a comb of resonances that preserve similar characteristics over a broad spectral interval. However, for many applications it is beneficial to selectively control of the quality factor (Q) of one or only some resonances. In this work we propose and experimentally validate the use of a resonant interferometric coupler to selectively change the Q-factor of a target resonance in an integrated silicon nitride microresonator. We show that its Q-factor can be continuously tuned from 65000 to 3 milions, leaving the untargeted resonances uperturbed. Our design can be scaled to independently control several resonances.
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- 2024
13. Frequency Dispersed Ion Acoustic Waves in the Near Sun Solar Wind: Signatures of Impulsive Ion Beams
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Malaspina, David M., Ergun, Robert E., Cairns, Iver H., Short, Benjamin, Verniero, Jaye L., Cattell, Cynthia, and Livi, Roberto
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics ,Physics - Space Physics - Abstract
This work reports a novel plasma wave observation in the near-Sun solar wind: frequency-dispersed ion acoustic waves. Similar waves were previously reported in association with interplanetary shocks or planetary bow shocks, but the waves reported here occur throughout the solar wind sunward of $\sim 60$ solar radii, far from any identified shocks. The waves reported here vary their central frequency by factors of 3 to 10 over tens of milliseconds, with frequencies that chirp up or down in time. Using a semi-automated identification algorithm, thousands of wave instances are recorded during each near-Sun orbit of the Parker Solar Probe spacecraft. Wave statistical properties are determined and used to estimate their plasma frame frequency and the energies of protons most likely to be resonant with these waves. Proton velocity distribution functions are explored for one wave interval, and proton enhancements that may be consistent with proton beams are observed. A conclusion from this analysis is that properties of the observed frequency-dispersed ion acoustic waves are consistent with driving by cold, impulsively accelerated proton beams near the ambient proton thermal speed. Based on the large number of observed waves and their properties, it is likely that the impulsive proton beam acceleration mechanism generating these waves is active throughout the inner heliosphere. This may have implications for acceleration of the solar wind.
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- 2024
14. The Independence of Magnetic Turbulent Power Spectra to the Presence of Switchbacks in the Inner Heliosphere
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Tatum, Peter, Malaspina, David, Chasapis, Alexandros, and Short, Benjamin
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics ,Physics - Space Physics - Abstract
An outstanding gap in our knowledge of the solar wind is the relationship between switchbacks and solar wind turbulence. Switchbacks are large fluctuations, even reversals, of the background magnetic field embedded in the solar wind flow. It has been proposed that switchbacks may form as a product of turbulence and decay via coupling with the turbulent cascade. In this work, we examine how properties of solar wind magnetic field turbulence vary in the presence or absence of switchbacks. Specifically, we use in-situ particle and fields measurements from Parker Solar Probe to measure magnetic field turbulent wave power, separately in the inertial and kinetic ranges, as a function of switchback magnetic deflection angle. We demonstrate that the angle between the background magnetic field and the solar wind velocity in the spacecraft frame ($\theta_{vB}$) strongly determines whether Parker Solar Probe samples wave power parallel or perpendicular to the background magnetic field. Further, we show that $\theta_{vB}$ is strongly modulated by the switchback magnetic deflection angle. In this analysis, we demonstrate that switchback deflection angle does not correspond to any significant increase in wave power in either the inertial range or at kinetic scales. This result implies that switchbacks do not strongly couple to the turbulent cascade in the inertial or kinetic ranges via turbulent wave-particle interactions. Therefore, we do not expect switchbacks to contribute significantly to solar wind heating through this type of energy conversion pathway, although contributions via other mechanisms, such as magnetic reconnection may still be significant., Comment: Words in text: 4315 Words in headers: 29 Words outside text (captions, etc.): 293 Number of headers: 10 Number of floats/tables/figures: 5 Number of math inlines: 165 Number of math displayed: 3
- Published
- 2024
15. Sublethal exposure to thiamethoxam and pyraclostrobin affects the midgut and Malpighian tubules of the stingless bee Frieseomelitta varia (Hymenoptera: Apidae: Meliponini)
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da Silva, Jaqueline Aparecida, Farder-Gomes, Cliver Fernandes, Barchuk, Angel Roberto, Malaspina, Osmar, and Nocelli, Roberta Cornélio Ferreira
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- 2024
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16. Semi-Supervised Diffusion Model for Brain Age Prediction
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Ijishakin, Ayodeji, Martin, Sophie, Townend, Florence, Agosta, Federica, Spinelli, Edoardo Gioele, Basaia, Silvia, Schito, Paride, Falzone, Yuri, Filippi, Massimo, Cole, James, and Malaspina, Andrea
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Brain age prediction models have succeeded in predicting clinical outcomes in neurodegenerative diseases, but can struggle with tasks involving faster progressing diseases and low quality data. To enhance their performance, we employ a semi-supervised diffusion model, obtaining a 0.83(p<0.01) correlation between chronological and predicted age on low quality T1w MR images. This was competitive with state-of-the-art non-generative methods. Furthermore, the predictions produced by our model were significantly associated with survival length (r=0.24, p<0.05) in Amyotrophic Lateral Sclerosis. Thus, our approach demonstrates the value of diffusion-based architectures for the task of brain age prediction.
- Published
- 2024
17. Reconstruction of Polarization Properties of Whistler Waves From Two Magnetic and Two Electric Field Components: Application to Parker Solar Probe Measurements
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Colomban, L., Agapitov, O. V., Krasnoselskikh, V., Kretzschmar, M., de Wit, T. Dudok, Karbashewski, S., Mozer, F. S., Bonnell, J. W., Bale, S., Malaspina, D., and Raouafi, N. E.
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Data Analysis, Statistics and Probability ,Physics - Instrumentation and Detectors ,Physics - Plasma Physics ,Physics - Space Physics - Abstract
The search-coil magnetometer (SCM) aboard Parker Solar Probe (PSP) measures the 3 Hz to 1 MHz magnetic field fluctuations. During Encounter 1, the SCM operated as expected; however, in March 2019, technical issues limited subsequent encounters to two components for frequencies below 1 kHz. Detrimentally, most whistler waves are observed in the affected frequency band where established techniques cannot extract the wave polarization properties under these conditions. Fortunately, the Electric Field Instrument aboard PSP measures two electric field components and covers the affected bandwidth. We propose a technique using the available electromagnetic fields to reconstruct the missing components by neglecting the electric field parallel to the background magnetic field. This technique is applicable with the assumptions of (a) low-frequency whistlers in the plasma frame relative to the electron cyclotron frequency; (b) a small propagation angle with respect to the background magnetic field; and (c) a large wave phase speed relative to the cross-field solar wind velocity. Critically, the method cannot be applied if the background magnetic field is aligned with the affected SCM coil. We have validated our method using burst mode measurements made before March 2019. The reconstruction conditions are satisfied for 80% of the burst mode whistlers detected during Encounter 1. We apply the method to determine the polarization of a whistler event observed after March 2019 during Encounter 2. Our novel method is an encouraging step toward analyzing whistler properties in affected encounters and improving our understanding of wave-particle interactions in the young solar wind.
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- 2024
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18. How long-lived grains dominate the shape of the Zodiacal Cloud
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Pokorny, Petr, Moorhead, Althea V., Kuchner, Marc J., Szalay, Jamey R., and Malaspina, David M.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Grain-grain collisions shape the 3-dimensional size and velocity distribution of the inner Zodiacal Cloud and the impact rates of dust on inner planets, yet they remain the least understood sink of zodiacal dust grains. For the first time, we combine the collisional grooming method combined with a dynamical meteoroid model of Jupiter-family comets (JFCs) that covers four orders of magnitude in particle diameter to investigate the consequences of grain-grain collisions in the inner Zodiacal Cloud. We compare this model to a suite of observational constraints from meteor radars, the Infrared Astronomical Satellite (IRAS), mass fluxes at Earth, and inner solar probes, and use it to derive the population and collisional strength parameters for the JFC dust cloud. We derive a critical specific energy of $Q^*_D=5\times10^5 \pm 4\times10^5 R_\mathrm{met}^{-0.24}$ J kg$^{-1}$ for particles from Jupiter-family comet particles, making them 2-3 orders of magnitude more resistant to collisions than previously assumed. We find that the differential power law size index $-4.2\pm0.1$ for particles generated by JFCs provides a good match to observed data. Our model provides a good match to the mass production rates derived from the Parker Solar Probe observations and their scaling with the heliocentric distance. The higher resistance to collisions of dust particles might have strong implications to models of collisions in solar and exo-solar dust clouds. The migration via Poynting-Roberson drag might be more important for denser clouds, the mass production rates of astrophysical debris disks might be overestimated, and the mass of the source populations might be underestimated. Our models and code are freely available online., Comment: 41 pages, 14 figures, 1 table - Submitted to The Planetary Science Journal (PSJ) - After 2nd review
- Published
- 2024
19. Parallel Inexact Levenberg-Marquardt Method for Nearly-Separable Nonlinear Least Squares
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Fodor, Lidija, Jakovetic, Dusan, Krejic, Natasa, and Malaspina, Greta
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Mathematics - Optimization and Control - Abstract
Motivated by localization problems such as cadastral maps refinements, we consider a generic Nonlinear Least Squares (NLS) problem of minimizing an aggregate squared fit across all nonlinear equations (measurements) with respect to the set of unknowns, e.g., coordinates of the unknown points' locations. In a number of scenarios, NLS problems exhibit a nearly-separable structure: the set of measurements can be partitioned into disjoint groups (blocks), such that the unknowns that correspond to different blocks are only loosely coupled. We propose an efficient parallel method, termed Parallel Inexact Levenberg Marquardt (PILM), to solve such generic large scale NLS problems. PILM builds upon the classical Levenberg-Marquard (LM) method, with a main novelty in that the nearly-block separable structure is leveraged in order to obtain a scalable parallel method. Therein, the problem-wide system of linear equations that needs to be solved at every LM iteration is tackled iteratively. At each (inner) iteration, the block-wise systems of linear equations are solved in parallel, while the problem-wide system is then handled via sparse, inexpensive inter-block communication. We establish strong convergence guarantees of PILM that are analogous to those of the classical LM; provide PILM implementation in a master-worker parallel compute environment; and demonstrate its efficiency on huge scale cadastral map refinement problems.
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- 2023
20. One-click annotation to improve segmentation by a convolutional neural network for PET images of head and neck cancer patients
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Rainio, Oona, Liedes, Joonas, Murtojärvi, Sarita, Malaspina, Simona, Kemppainen, Jukka, and Klén, Riku
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- 2024
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21. Salvage Magnetic Resonance Imaging–guided Transurethral Ultrasound Ablation for Localized Radiorecurrent Prostate Cancer
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Mikael Anttinen, Pietari Mäkelä, Pertti Nurminen, Heikki Pärssinen, Simona Malaspina, Teija Sainio, Mikael Högerman, Pekka Taimen, Roberto Blanco Sequeiros, and Peter J. Boström
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Ablation therapy ,Biochemical recurrence ,Local recurrence ,Magnetic resonance imaging–guided transurethral ultrasound ablation ,Prostate cancer ,Radiorecurrent prostate cancer ,Diseases of the genitourinary system. Urology ,RC870-923 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background and objective: Toxicity from local salvage therapy for radiorecurrent prostate cancer (PCa) remains a concern. This phase 2 study evaluates the outcomes of salvage magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (sTULSA). Methods: Men with biochemically relapsed, biopsy-proven PCa following definitive radiotherapy underwent whole- or partial-gland sTULSA (NCT03350529). Prostate-confined recurrence was confirmed by MRI and prostate-specific membrane antigen (PSMA) positron emission tomography (PET) computed tomography (CT). The primary endpoints were safety (Clavien-Dindo classification) and efficacy (prostate-specific antigen [PSA], PSMA PET-CT, and MRI-targeted biopsy at 12 mo). The secondary endpoints included functional and survival outcomes. Key findings and limitations: Thirty-nine patients underwent sTULSA (64% whole gland), with a median age of 73 yr (interquartile range [IQR]: 69–77) and PSA of 3.3 ng/ml (IQR: 2–6.2). Three patients had undergone prior salvage therapy, 16 were receiving hormonal therapy at enrollment, and 12 had a history of transurethral interventions. Eighteen patients had incidental urethral strictures on baseline cystoscopy. Over a median follow-up of 40 mo (IQR: 24–55), 56% experienced adverse events. Severe genitourinary toxicity (Clavien-Dindo ≥3 or hospitalization) occurred in 28%, including three patients with puboprostatic fistulas and two patients requiring cystectomy. Leak-free continence was maintained in 53%. At 12 mo, 89% showed no cancer in the targeted area, with a median PSA reduction of 95% (p
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- 2025
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22. An experimental protocol to access immersiveness in video games
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Malaspina, Marika, Barbato, Jessica Amianto, Cremaschi, Marco, Gasparini, Francesca, Grossi, Alessandra, and Saibene, Aurora
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Computer Science - Human-Computer Interaction - Abstract
In the video game industry, great importance is given to the experience that the user has while playing a game. In particular, this experience benefits from the players' perceived sense of being in the game or immersion. The level of user immersion depends not only on the game's content but also on how the game is displayed, thus on its User Interface (UI) and the Head's-Up Display (HUD). Another factor influencing immersiveness that has been found in the literature is the player's expertise: the more experience the user has with a specific game, the less they need information on the screen to be immersed in the game. Player's level of immersion can be accessed by using both questionnaires of their perceived experience and exploiting their behavioural and physiological responses while playing the target game. Therefore, in this paper, we propose an experimental protocol to access immersiveness of gamers while playing a third-person shooter (Fortnite) with UIs with a standard, a dietetic, and a proposed HUD. A subjective evaluation of the immersion will be provided by completing the Immersive Experience Questionnaire (IEQ), while objective indicators will be provided by face tracking, behaviour and physiological responses analyses. The ultimate goal of this study is to define guidelines for video game UI development that can enhance the players' immersion., Comment: Accepted at the Italian Workshop on Artificial Intelligence for Human Machine Interaction (AIxHMI 2023), November 06, 2023, Rome, Italy
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- 2023
23. Inexact Gauss-Newton methods with matrix approximation by sampling for nonlinear least-squares and systems
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Bellavia, Stefania, Malaspina, Greta, and Morini, Benedetta
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Mathematics - Optimization and Control ,Mathematics - Numerical Analysis - Abstract
We develop and analyze stochastic inexact Gauss-Newton methods for nonlinear least-squares problems and for nonlinear systems ofequations. Random models are formed using suitable sampling strategies for the matrices involved in the deterministic models. The analysis of the expected number of iterations needed in the worst case to achieve a desired level of accuracy in the first-order optimality condition provides guidelines for applying sampling and enforcing, with \minor{a} fixed probability, a suitable accuracy in the random approximations. Results of the numerical validation of the algorithms are presented.
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- 2023
24. The Mediating Role of Self-Regulation in the Relationship between Parenting Behaviors and Early Mathematical Development in Peruvian Preschool Children
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Malaspina, Martín and Garcia Ampudia, Lupe
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A significant way to contribute in the analysis of deficiencies in school performance, a known issue particularly in mathematics, is by delving into children's development of informal mathematics during their early childhood, and thus have better elements to intervene in a more timely, effective manner. From this point of view, this study analyzes how the relationship between parenting behavior and early mathematics can be mediated by the development of self-regulation in children. The sample of the study is made of 85 students, between 5 and 6 years old, who are in their last year of preschool in two public schools in Lima. The instruments used are the Spanish translations of the Test of Early Mathematics Ability--3, Head-Toes-Knees-Shoulders task and Parent Behavior Inventory. The main results show that self-regulation in children and their caregivers' parenting behavior are significant predicting variables in early mathematical development. Specifically, the findings suggest that self-regulation in children can significantly mediate the relationship between the dimension of support/engagement in parenting behavior and the development of early mathematics in children during preschool.
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- 2022
25. Synergies between interstellar dust and heliospheric science with an Interstellar Probe
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Sterken, Veerle J., Hunziker, Silvan, Dialynas, Kostas, Leitner, Jan, Sommer, Maximilian, Srama, Ralf, Baalmann, Lennart R., Li, Aigen, Herbst, Konstantin, Galli, André, Brandt, Pontus, Riebe, My, Baggaley, Jack, Blanc, Michel, Czechowski, Andrej, Effenberger, Frederic, Fields, Brian, Frisch, Priscilla, Horanyi, Mihaly, Hsu, Hsiang-Wen, Khawaja, Nozair, Krüger, Harald, Kurth, Bill S., Ligterink, Niels F. W., Linsky, Jeffrey L., Lisse, Casey, Malaspina, David, Miller, Jesse A., Opher, Merav, Poppe, Andrew R., Postberg, Frank, Provornikova, Elena, Redfield, Seth, Richardson, John, Rowan-Robinson, Michael, Scherer, Klaus, Shen, Mitchell M., Slavin, Jon D., Sternovsky, Zoltan, Stober, Gunter, Strub, Peter, Szalay, Jamey, and Trieloff, Mario
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We discuss the synergies between heliospheric and dust science, the open science questions, the technological endeavors and programmatic aspects that are important to maintain or develop in the decade to come. In particular, we illustrate how we can use interstellar dust in the solar system as a tracer for the (dynamic) heliosphere properties, and emphasize the fairly unexplored, but potentially important science question of the role of cosmic dust in heliospheric and astrospheric physics. We show that an Interstellar Probe mission with a dedicated dust suite would bring unprecedented advances to interstellar dust research, and can also contribute-through measuring dust - to heliospheric science. This can, in particular, be done well if we work in synergy with other missions inside the solar system, thereby using multiple vantage points in space to measure the dust as it `rolls' into the heliosphere. Such synergies between missions inside the solar system and far out are crucial for disentangling the spatially and temporally varying dust flow. Finally, we highlight the relevant instrumentation and its suitability for contributing to finding answers to the research questions., Comment: 18 pages, 7 Figures, 5 Tables. Originally submitted as white paper for the National Academies Decadal Survey for Solar and Space Physics 2024-2033
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- 2023
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26. 't Hooft bundles on the complete flag threefold and moduli spaces of instantons
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Antonelli, Vincenzo, Malaspina, Francesco, Marchesi, Simone, and Pons-Llopis, Joan
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Mathematics - Algebraic Geometry ,Primary: 14F06, 14J60. Secondary: 14J45, 14D21 - Abstract
In this work we study the moduli space of instanton bundles on the flag twistor space $F:=F(0,1,2)$. We stratify them in terms of the minimal twist supporting global sections and we introduce the notion of (special) 't Hooft bundle on $F$. In particular we prove that there exist $\mu$-stable 't Hooft bundles for each admissible charge $k$. We completely describe the geometric structure of the moduli space of (special) 't Hooft bundles for arbitrary charge $k$. Along the way to reach these goals, we describe the possible structures of multiple curves supported on some rational curves in $F$ as well as the moduli space of del Pezzo surfaces realized as hyperplane sections of $F$. Finally we investigate the splitting behaviour of 't Hooft bundles when restricted to conics., Comment: 37 pages. Comments are welcome
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- 2023
27. Castelnuovo-Mumford Regularity and Splitting Criteria for Logarithmic Bundles over Rational Normal Scroll Surfaces
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Di Gennaro, Roberta and Malaspina, Francesco
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Mathematics - Algebraic Geometry ,14F05, 14J60 - Abstract
We introduce and study a notion of Castelnuovo-Mumford regularity suitable for rational normal scroll surfaces. In this setting we prove analogs of some classical properties. We prove splitting criteria for coherent sheaves and a characterization of Ulrich bundles. Finally we study logarithmic bundles associated to arrangements of lines and rational curves.
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- 2023
28. Quantum Molecular Dynamics Approach to Understanding Interactions in Betaine Chloride and Amino Acid Natural Deep Eutectic Solvents
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Eudes Eterno Fileti, Henrique de Araujo Chagas, Guilherme Colherinhas, and Thaciana Malaspina
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Physical and theoretical chemistry ,QD450-801 - Published
- 2024
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29. Distributed Inexact Newton Method with Adaptive Step Sizes
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Jakovetic, Dusan, Krejic, Natasa, and Malaspina, Greta
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Mathematics - Optimization and Control - Abstract
We consider two formulations for distributed optimization wherein $N$ agents in a generic connected network solve a problem of common interest: distributed personalized optimization and consensus optimization. A new method termed DINAS (Distributed Inexact Newton method with Adaptive Stepsize) is proposed. DINAS employs large adaptively computed step-sizes, requires a reduced global parameters knowledge with respect to existing alternatives, and can operate without any local Hessian inverse calculations nor Hessian communications. When solving personalized distributed learning formulations, DINAS achieves quadratic convergence with respect to computational cost and linear convergence with respect to communication cost, the latter rate being independent of the local functions condition numbers or of the network topology. When solving consensus optimization problems, DINAS is shown to converge to the global solution. Extensive numerical experiments demonstrate significant improvements of DINAS over existing alternatives. As a result of independent interest, we provide for the first time convergence analysis of the Newton method with the adaptive Polyak's step-size when the Newton direction is computed inexactly in centralized environment.
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- 2023
30. Whistler Wave Observations by \textit{Parker Solar Probe} During Encounter $1$: Counter-Propagating Whistlers Collocated with Magnetic Field Inhomogeneities and their Application to Electric Field Measurement Calibration
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Karbashewski, S., Agapitov, O. V., Kim, H. Y., Mozer, F. S., Bonnell, J. W., Froment, C., de Wit, T. Dudok, Bale, S. D., Malaspina, D., and Raouafi, N. E.
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Physics - Space Physics ,Physics - Plasma Physics - Abstract
Observations of the young solar wind by the Parker Solar Probe (PSP) mission reveal the existence of intense plasma wave bursts with frequencies between $0.05$ -- $0.20 f_\mathrm{ce}$ (tens of Hz up to ${\sim}300$ Hz) in the spacecraft frame. The wave bursts are often collocated with inhomogeneities in the solar wind magnetic field, such as local dips in magnitude or sudden directional changes. The observed waves are identified as electromagnetic whistler waves that propagate either sunward, anti-sunward, or in counter-propagating configurations during different burst events. Being generated in the solar wind flow the waves experience significant Doppler down-shift and up-shift {of wave frequency} in the spacecraft frame for sunward and anti-sunward waves, respectively. Their peak amplitudes can be larger than $2$~nT, where such values represent up to $10\%$ of the background magnetic field during the interval of study. The amplitude is maximum for propagation parallel to the background magnetic field. We (i) evaluate the properties of these waves by reconstructing their parameters in the plasma frame, (ii) estimate the effective length of the PSP electric field antennas at whistler frequencies, and (iii) discuss the generation mechanism of these waves.
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- 2023
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31. Variability of Antenna Signals From Dust Impacts
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Shen, Mitchell M., Sternovsky, Zoltan, and Malaspina, David M.
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Physics - Space Physics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics - Abstract
Electric field instruments carried by spacecraft (SC) are complementary to dedicated dust detectors by registering transient voltage perturbations caused by impact-generated plasma. The signal waveform contains information about the interaction between the impact-generated plasma cloud and the elements of SC-antenna system. The variability of antenna signals from dust impacts has not yet been systematically characterized. A set of laboratory measurements are performed to characterize signal variations in response to SC parameters (bias voltage and antenna configuration) and impactor parameters (impact speed and composition). The measurements demonstrate that dipole antenna configurations are sensitive to dust impacts and that the detected signals vary with impact location. When dust impacts occur at low speeds, the antennas typically register smaller amplitudes and less characteristic impact signal shapes. In this case, impact event identification may be more challenging due to lower signal-to-noise ratios and/or more variable waveforms shapes, indicating the compound nature of nonfully developed impact-generated plasmas. To investigate possible variations in the impacting materials, the measurements are carried out using two dust samples with different mass densities: iron and aluminum. No significant variations of the measured waveform or plasma parameters obtained from data analysis are observed between the two materials used., Comment: Manuscript accepted online by JGR: Space Physics on 22 March 2023
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- 2023
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32. Laboratory Study of Antenna Signals Generated by Dust Impacts on Spacecraft
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Shen, Mitchell M., Sternovsky, Zoltan, Horányi, Mihály, Hsu, Hsiang-Wen, and Malaspina, David M.
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Physics - Space Physics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics - Abstract
Space missions often carry antenna instruments that are sensitive to dust impacts, however, the understanding of signal generation mechanisms remained incomplete. A signal generation model in an analytical form is presented that provides a good agreement with laboratory measurements. The model is based on the direct and induced charging of the spacecraft from the collected and escaping fraction of free charges from the impact-generated plasma cloud. A set of laboratory experiments is performed using a 20:1 scaled-down model of the Cassini spacecraft in a dust accelerator facility. The results show that impact plasmas can be modeled as a plume of ions streaming away from the impact location and a cloud of isotropically expanding electrons. The fitting of the model to the collected antenna waveforms provides some of the key parameters of the impact plasma. The model also shows that the amplitudes of the impact signals can be significantly reduced in typical space environments due to the discharging effects in the ambient plasma., Comment: Manuscript accepted online by JGR: Space Physics on 05 April 2021
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- 2023
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33. Electrostatic Model for Antenna Signal Generation From Dust Impacts
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Shen, Mitchell M., Sternovsky, Zoltan, Garzelli, Alessandro, and Malaspina, David M.
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Physics - Space Physics ,Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics - Abstract
Dust impacts on spacecraft are commonly detected by antenna instruments as transient voltage perturbations. The signal waveform is generated by the interaction between the impact-generated plasma cloud and the elements of the antenna-spacecraft system. A general electrostatic model is presented that includes the two key elements of the interaction, namely the charge recollected from the impact plasma by the spacecraft and the fraction electrons and cations that escape to infinity. The clouds of escaping electrons and cations generate induced signals, and their vastly different escape speeds are responsible for the characteristic shape of the waveforms. The induced signals are modeled numerically for the geometry of the system and the location of the impact. The model employs a Maxwell capacitance matrix to keep track of the mutual interaction between the elements of the system. A new reduced-size model spacecraft is constructed for laboratory measurements using the dust accelerator facility. The model spacecraft is equipped with four antennas: two operating in a monopole mode, and one pair configured as a dipole. Submicron-sized iron dust particles accelerated to > 20 km/s are used for test measurements, where the waveforms of each antenna are recorded. The electrostatic model provides a remarkably good fit to the data using only a handful of physical fitting parameters, such as the escape speeds of electrons and cations. The presented general model provides the framework for analyzing antenna waveforms and is applicable for a range of space missions investigating the distribution of dust particles in relevant environments., Comment: Manuscript accepted online by JGR: Space Physics on 13 August 2021
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- 2023
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34. Ulrich bundles of arbitrary rank on Segre-Veronese varieties
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Malaspina, Francesco
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Mathematics - Algebraic Geometry - Abstract
We generalize the results by Eisenbud and Schreyer about Ulrich bundles over Veronese varieties to Segre-Veronese varieties. We discuss the range where we have natural cohomology and we construct multigraded resolutions and monads for Ulrich bundles of any rank. Moreover we give cohomological characterizations for significant families of bundles., Comment: 18 pages, the final version will appear on J. of Algebra
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- 2023
35. New Observations of Solar Wind 1/f Turbulence Spectrum from Parker Solar Probe
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Huang, Zesen, Sioulas, Nikos, Shi, Chen, Velli, Marco, Bowen, Trevor, Davis, Nooshin, Chandran, B. D. G., Kang, Ning, Shi, Xiaofei, Huang, Jia, Bale, Stuart D., Kasper, J. C., Larson, Davin E., Livi, Roberto, Whittlesey, P. L., Rahmati, Ali, Paulson, Kristoff, Stevens, M., Case, A. W., de Wit, Thierry Dudok, Malaspina, David M., Bonnell, J. W., Goetz, Keith, Harvey, Peter R., and MacDowall, Robert J.
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Fluid Dynamics ,Physics - Geophysics ,Physics - Plasma Physics ,Physics - Space Physics - Abstract
The trace magnetic power spectrum in the solar wind is known to be characterized by a double power law at scales much larger than the proton gyro-radius, with flatter spectral exponents close to -1 found at the lower frequencies below an inertial range with indices closer to $[-1.5,-1.6]$. The origin of the $1/f$ range is still under debate. In this study, we selected 109 magnetically incompressible solar wind intervals ($\delta |\boldsymbol B|/|\boldsymbol B| \ll 1$) from Parker Solar Probe encounters 1 to 13 which display such double power laws, with the aim of understanding the statistics and radial evolution of the low frequency power spectral exponents from Alfv\'en point up to 0.3 AU. New observations from closer to the sun show that in the low frequency range solar wind turbulence can display spectra much shallower than $1/f$, evolving asymptotically to $1/f$ as advection time increases, indicating a dynamic origin for the $1/f$ range formation. We discuss the implications of this result on the Matteini et al. (2018) conjecture for the $1/f$ origin as well as example spectra displaying a triple power law consistent with the model proposed by Chandran et al. (2018), supporting the dynamic role of parametric decay in the young solar wind. Our results provide new constraints on the origin of the $1/f$ spectrum and further show the possibility of the coexistence of multiple formation mechanisms., Comment: Accepted by ApJL
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- 2023
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36. A Rasch Modeling Approach for Measuring Young Children's Informal Mathematics in Peru
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Malaspina, Martín and Arias, Benito
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One of the strongest predictors of future academic achievement is the early and informal math skills children begin their school studies. Because of this, it is essential to have proper tools for measuring the development of mathematical thinking at an early age to be able to intervene in a timelier, more effective way. The purpose of this research is to calibrate the items of informal mathematics from the test of early mathematics ability--third edition (TEMA-3) by applying the Rasch model. A total of 148 Peruvian preschool children (ranging in age from five to six years) participated in the study. The results show good psychometric properties of the informal mathematics dimension of the instrument, which indicates a good fit of the student sample, the items to the proposed model and a tendency toward unbiased items. We further determined that the items analyzed exhibit a consistent internal structure at the theoretical level.
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- 2022
37. Whistler waves generated inside magnetic dips in the young solar wind: observations of the Search-Coil Magnetometer on board Parker Solar Probe
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Froment, C., Agapitov, O. V., Krasnoselskikh, V., Karbashewski, S., de Wit, T. Dudok, Larosa, A., Colomban, L., Malaspina, D., Kretzschmar, M., Jagarlamudi, V. K., Bale, S. D., Bonnell, J. W., Mozer, F. S., and Pulupa, M.
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Space Physics - Abstract
Context. Whistler waves are electromagnetic waves produced by electron-driven instabilities, that in turn can reshape the electron distributions via wave-particle interactions. In the solar wind, they are one of the main candidates for explaining the scattering of the strahl electron population into the halo at increasing radial distances from the Sun and for subsequently regulating the solar wind heat flux. However, it is unclear what type of instability dominates to drive whistlers in the solar wind. Aims. Our goal is to study whistler wave parameters in the young solar wind sampled by Parker Solar Probe (PSP). The wave normal angle (WNA) in particular is a key parameter to discriminate between the generation mechanisms of these waves. Methods. We analyze the cross-spectral matrices of magnetic fieldfluctuations measured by the Search-Coil Magnetometer (SCM) and processed by the Digital Fields Board (DFB) from the FIELDS suite during PSP's first perihelion. Results. Among the 2701 wave packets detected in the cross spectra, namely individual bins in time and frequency, most were quasi-parallel to the background magnetic field but a significant part (3%) of observed waves had oblique (> 45{\deg}) WNA. The validation analysis conducted with the time-series waveforms reveal that this percentage is a lower limit. Moreover, we find that about 64% of the whistler waves detected in the spectra are associated with at least one magnetic dip. Conclusions. We conclude that magnetic dips provides favorable conditions for the generation of whistler waves. We hypothesize that the whistlers detected in magnetic dips are locally generated by the thermal anisotropy as quasi-parallel and can gain obliqueness during their propagation. We finally discuss the implication of our results for the scattering of the strahl in the solar wind., Comment: 15 pages, 14 figures, recommended for publication in A&A
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- 2023
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38. On the evolution of the Anisotropic Scaling of Magnetohydrodynamic Turbulence in the Inner Heliosphere
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Sioulas, Nikos, Velli, Marco, Huang, Zesen, Shi, Chen, Bowen, Trevor A., Chandran, B. D. G., Liodis, Ioannis, Davis, Nooshin, Bale, Stuart D., Horbury, T. S., de Wit, Thierry Dudok, Larson, Davin, Kasper, Justin, Owen, Christopher J., Stevens, Michael L., Case, Anthony, Pulupa, Marc, Malaspina, David M., Bonnell, J. W., Goetz, Keith, Harvey, Peter R., and MacDowall, Robert J.
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Physics - Space Physics ,Astrophysics - High Energy Astrophysical Phenomena ,Physics - Plasma Physics - Abstract
We analyze a merged Parker Solar Probe ($PSP$) and Solar Orbiter ($SO$) dataset covering heliocentric distances $13 \ R_{\odot} \lesssim R \lesssim 220$ $R_{\odot}$ to investigate the radial evolution of power and spectral-index anisotropy in the wavevector space of solar wind turbulence. Our results show that anisotropic signatures of turbulence display a distinct radial evolution when fast, $V_{sw} \geq ~ 400 ~km ~s^{-1}$, and slow, $V_{sw} \leq ~ 400 ~km ~s^{-1}$, wind streams are considered. The anisotropic properties of slow wind in Earth orbit are consistent with a ``critically balanced'' cascade, but both spectral-index anisotropy and power anisotropy diminish with decreasing heliographic distance. Fast streams are observed to roughly retain their near-Sun anisotropic properties, with the observed spectral index and power anisotropies being more consistent with a ``dynamically aligned'' type of cascade, though the lack of extended fast-wind intervals makes it difficult to accurately measure the anisotropic scaling. A high-resolution analysis during the first perihelion of PSP confirms the presence of two sub-ranges within the inertial range, which may be associated with the transition from weak to strong turbulence. The transition occurs at $\kappa d_{i} \approx 6 \times 10^{-2}$, and signifies a shift from -5/3 to -2 and -3/2 to -1.57 scaling in parallel and perpendicular spectra, respectively. Our results provide strong observational constraints for anisotropic theories of MHD turbulence in the solar wind., Comment: Accepted to APJ
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- 2023
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39. Parker Solar Probe: Four Years of Discoveries at Solar Cycle Minimum
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Raouafi, N. E., Matteini, L., Squire, J., Badman, S. T., Velli, M., Klein, K. G., Chen, C. H. K., Matthaeus, W. H., Szabo, A., Linton, M., Allen, R. C., Szalay, J. R., Bruno, R., Decker, R. B., Akhavan-Tafti, M., Agapitov, O. V., Bale, S. D., Bandyopadhyay, R., Battams, K., Berčič, L., Bourouaine, S., Bowen, T., Cattell, C., Chandran, B. D. G., Chhiber, R., Cohen, C. M. S., D'Amicis, R., Giacalone, J., Hess, P., Howard, R. A., Horbury, T. S., Jagarlamudi, V. K., Joyce, C. J., Kasper, J. C., Kinnison, J., Laker, R., Liewer, P., Malaspina, D. M., Mann, I., McComas, D. J., Niembro-Hernandez, T., Panasenco, O., Pokorný, P., Pusack, A., Pulupa, M., Perez, J. C., Riley, P., Rouillard, A. P., Shi, C., Stenborg, G., Tenerani, A., Verniero, J. L., Viall, N., Vourlidas, A., Wood, B. E., Woodham, L. D., and Woolley, T.
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics ,Physics - Space Physics - Abstract
Launched on 12 Aug. 2018, NASA's Parker Solar Probe had completed 13 of its scheduled 24 orbits around the Sun by Nov. 2022. The mission's primary science goal is to determine the structure and dynamics of the Sun's coronal magnetic field, understand how the solar corona and wind are heated and accelerated, and determine what processes accelerate energetic particles. Parker Solar Probe returned a treasure trove of science data that far exceeded quality, significance, and quantity expectations, leading to a significant number of discoveries reported in nearly 700 peer-reviewed publications. The first four years of the 7-year primary mission duration have been mostly during solar minimum conditions with few major solar events. Starting with orbit 8 (i.e., 28 Apr. 2021), Parker flew through the magnetically dominated corona, i.e., sub-Alfv\'enic solar wind, which is one of the mission's primary objectives. In this paper, we present an overview of the scientific advances made mainly during the first four years of the Parker Solar Probe mission, which go well beyond the three science objectives that are: (1) Trace the flow of energy that heats and accelerates the solar corona and solar wind; (2) Determine the structure and dynamics of the plasma and magnetic fields at the sources of the solar wind; and (3) Explore mechanisms that accelerate and transport energetic particles., Comment: 157 pages, 65 figures
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- 2023
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40. Clinical standards for drug-susceptible TB in children and adolescents.
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Chiang, S, Graham, S, Schaaf, H, Marais, B, SantAnna, C, Sharma, S, Starke, J, Triasih, R, Achar, J, Amanullah, F, Armitage, L, Aurilio, R, Centis, R, Chabala, C, Cruz, A, Demers, A-M, du Preez, K, Enimil, A, Furin, J, Garcia-Prats, A, Gonzalez, N, Hoddinott, G, Isaakidis, P, Jaganath, D, Kabra, S, Kampmann, B, Kay, A, Kitai, I, Lopez-Varela, E, Maleche-Obimbo, E, Malaspina, F, Velásquez, J, Nuttall, J, Oliwa, J, Andrade, I, Perez-Velez, C, Rabie, H, Seddon, J, Sekadde, M, Shen, A, Skrahina, A, Soriano-Arandes, A, Steenhoff, A, Tebruegge, M, Tovar, M, Tsogt, B, van der Zalm, M, Welch, H, Migliori, G, and Buck, William
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Adolescent ,Child ,Humans ,Tuberculosis ,Meningeal ,Standard of Care ,Delphi Technique ,Practice Guidelines as Topic - Abstract
BACKGROUND: These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.METHODS: Fifty-two global experts in paediatric TB participated in a Delphi consensus process. After eight rounds of revisions, 51/52 (98%) participants endorsed the final document.RESULTS: Eight standards were identified: Standard 1, Age and developmental stage are critical considerations in the assessment and management of TB; Standard 2, Children and adolescents with symptoms and signs of TB disease should undergo prompt evaluation, and diagnosis and treatment initiation should not depend on microbiological confirmation; Standard 3, Treatment initiation is particularly urgent in children and adolescents with presumptive TB meningitis and disseminated (miliary) TB; Standard 4, Children and adolescents should be treated with an appropriate weight-based regimen; Standard 5, Treating TB infection (TBI) is important to prevent disease; Standard 6, Children and adolescents should receive home-based/community-based treatment support whenever possible; Standard 7, Children, adolescents, and their families should be provided age-appropriate support to optimise engagement in care and clinical outcomes; and Standard 8, Case reporting and contact tracing should be conducted for each child and adolescent.CONCLUSION: These consensus-based clinical standards, which should be adapted to local contexts, will improve the care of children and adolescents affected by TB.
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- 2023
41. Refeeding syndrome and psychopharmacological interventions in children and adolescents with Anorexia Nervosa: a focus on olanzapine-related modifications of electrolyte balance
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Pruccoli, Jacopo, Barbieri, Elena, Visconti, Caterina, Pranzetti, Beatrice, Pettenuzzo, Ilaria, Moscano, Filomena, Malaspina, Elisabetta, Marino, Marastella, Valeriani, Beatrice, and Parmeggiani, Antonia
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- 2024
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42. Linear convergence rate analysis of a class of exact first-order distributed methods for weight-balanced time-varying networks and uncoordinated step sizes
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Malaspina, Greta, Jakovetić, Dušan, and Krejić, Nataša
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- 2024
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43. Analytical Inverse QCD Coupling Constant Approach and Its Result for αs
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Rocco Malaspina, Lorenzo Pierini, Olga Shekhovtsova, and Simone Pacetti
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APT ,analytical inverse QCD coupling constant ICC ,regularization functions ,α s ( M Z 2 ) ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
We propose a model for the QCD running coupling constant based on the analytical inverse QCD coupling constant concept with an additional regularization in the low momentum region. Analyticity in the q2-complex plane, where q is the four-momentum transfer, is imposed by methods of the Analytic Perturbation Theory. The model incorporates a peculiar low-momentum behavior for αs(q2) as a divergence at q2=0 to retrieve color confinement, without spoiling its correct high-momentum behavior. This was achieved by means of a two-parameter regularization function, for which we considered three possible analytic expressions. In fact, within the framework of the Analytic Perturbation Theory, αs(q2) assumes a finite value for q2=0, at all perturbative orders (infrared stability), hence the infrared divergence cannot be implemented. For this reason, we found it more straightforward to work with its reciprocal, namely, εs(q2)=1/αs(q2), imposing its vanishing at the origin of the q2-complex plane via the multiplication of the aforementioned regularizing functions and the spectral density. Once the two free parameters of the regularization functions were settled by fitting to the experimental values of αs(q2) at the momenta where these data were available and reliable, the model could reproduce the QCD running coupling constant at any other momentum transferred.
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- 2024
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44. Space Plasma Physics: A Review
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Tsurutani, Bruce T., Zank, Gary P., Sterken, Veerle J., Shibata, Kazunari, Nagai, Tsugunobu, Mannucci, Anthony J., Malaspina, David M., Lakhina, Gurbax S., Kanekal, Shrikanth G., Hosokawa, Keisuke, Horne, Richard B., Hajra, Rajkumar, Glassmeier, Karl-Heinz, Gaunt, C. Trevor, Chen, Peng-Fei, and Akasofu, Syun-Ichi
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Physics - Space Physics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Owing to the ever-present solar wind, our vast solar system is full of plasmas. The turbulent solar wind, together with sporadic solar eruptions, introduces various space plasma processes and phenomena in the solar atmosphere all the way to the Earth's ionosphere and atmosphere and outward to interact with the interstellar media to form the heliopause and termination shock. Remarkable progress has been made in space plasma physics in the last 65 years, mainly due to sophisticated in-situ measurements of plasmas, plasma waves, neutral particles, energetic particles, and dust via space-borne satellite instrumentation. Additionally high technology ground-based instrumentation has led to new and greater knowledge of solar and auroral features. As a result, a new branch of space physics, i.e., space weather, has emerged since many of the space physics processes have a direct or indirect influence on humankind. After briefly reviewing the major space physics discoveries before rockets and satellites, we aim to review all our updated understanding on coronal holes, solar flares and coronal mass ejections, which are central to space weather events at Earth, solar wind, storms and substorms, magnetotail and substorms, emphasizing the role of the magnetotail in substorm dynamics, radiation belts/energetic magnetospheric particles, structures and space weather dynamics in the ionosphere, plasma waves, instabilities, and wave-particle interactions, long-period geomagnetic pulsations, auroras, geomagnetically induced currents (GICs), planetary magnetospheres and solar/stellar wind interactions with comets, moons and asteroids, interplanetary discontinuities, shocks and waves, interplanetary dust, space dusty plasmas and solar energetic particles and shocks, including the heliospheric termination shock. This paper is aimed to provide a panoramic view of space physics and space weather., Comment: Accepted for publication in IEEE Transactions on Plasma Science (2022)
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- 2022
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45. Magnetic field spectral evolution in the inner heliosphere
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Sioulas, Nikos, Huang, Zesen, Shi, Chen, Velli, Marco, Tenerani, Anna, Vlahos, Loukas, Bowen, Trevor A., Bale, Stuart D., Bonnell, J. W., Harvey, P. R., Larson, Davin, Pulupa, arc, Livi, Roberto, Woodham, L. D., Horbury, T. S., Stevens, Michael L., de Wit, T. Dudok, MacDowall, R. J., Malaspina, David M., Goetz, K., Huang, Jia, Kasper, Justin, Owen, Christopher J., Maksimović, Milan, Louarn, P., and Fedorov, A.
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Astrophysics - Solar and Stellar Astrophysics ,Physics - Plasma Physics ,Physics - Space Physics - Abstract
Parker Solar Probe and Solar Orbiter data are used to investigate the radial evolution of magnetic turbulence between $0.06 ~ \lesssim R ~\lesssim 1$ au. The spectrum is studied as a function of scale, normalized to the ion inertial scale $d_{i}$. In the vicinity of the Sun, the inertial range is limited to a narrow range of scales and exhibits a power-law exponent of, $\alpha_{B} = -3/2$, independent of plasma parameters. The inertial range grows with distance, progressively extending to larger spatial scales, while steepening towards a $\alpha_{B} =-5/3$ scaling. It is observed that spectra for intervals with large magnetic energy excesses and low Alfv\'enic content steepen significantly with distance, in contrast to highly Alfv\'enic intervals that retain their near-Sun scaling. The occurrence of steeper spectra in slower wind streams may be attributed to the observed positive correlation between solar wind speed and Alfv\'enicity., Comment: Accepted to APJ letters with minor revisions
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- 2022
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46. Microfluidic-Based Analytical Devices (μFADs)
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Medina-Castillo, Antonio L., Malaspina, Roccopio, López Aveiga, Melany Gisell, Fernández Ramos, María Dolores, Jiménez-Carvelo, Ana María, editor, Arroyo-Cerezo, Alejandra, editor, and Cuadros-Rodríguez, Luis, editor
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- 2024
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47. The Evolving Concept of Viruses and Immune System Interaction in Head and Neck Neoplasms
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Petrelli, Federica, Malaspina, Lara, Piane, Riccardo Mario, Ambrosio, Maria Raffaella, Rezaei, Nima, Series Editor, Aguiar, Rodrigo, Editorial Board Member, Ahmed, Atif A., Editorial Board Member, Ambrosio, Maria R., Editorial Board Member, Artac, Mehmet, Editorial Board Member, Augustine, Tanya N., Editorial Board Member, Bambauer, Rolf, Editorial Board Member, Bhat, Ajaz Ahmad, Editorial Board Member, Bertolaccini, Luca, Editorial Board Member, Bianchini, Chiara, Editorial Board Member, Cavic, Milena, Editorial Board Member, Chakrabarti, Sakti, Editorial Board Member, Cho, William C. S., Editorial Board Member, Czarnecka, Anna M., Editorial Board Member, Domingues, Cátia, Editorial Board Member, Eşkazan, A. Emre, Editorial Board Member, Fares, Jawad, Editorial Board Member, Fonseca Alves, Carlos E., Editorial Board Member, Fru, Pascaline, Editorial Board Member, Da Gama Duarte, Jessica, Editorial Board Member, García, Mónica C., Editorial Board Member, Gener, Melissa A.H., Editorial Board Member, Estrada Guadarrama, José Antonio, Editorial Board Member, Hargadon, Kristian M., Editorial Board Member, Holvoet, Paul, Editorial Board Member, Jurisic, Vladimir, Editorial Board Member, Kabir, Yearul, Editorial Board Member, Katsila, Theodora, Editorial Board Member, Kleeff, Jorg, Editorial Board Member, Liang, Chao, Editorial Board Member, Tan, Mei Lan, Editorial Board Member, Li, Weijie, Editorial Board Member, Prado López, Sonia, Editorial Board Member, Macha, Muzafar A., Editorial Board Member, Malara, Natalia, Editorial Board Member, Orhan, Adile, Editorial Board Member, Prado-Garcia, Heriberto, Editorial Board Member, Pérez-Velázquez, Judith, Editorial Board Member, Rashed, Wafaa M., Editorial Board Member, Sanguedolce, Francesca, Editorial Board Member, Sorrentino, Rosalinda, Editorial Board Member, Shubina, Irina Zh., Editorial Board Member, de Araujo, Heloisa Sobreiro Selistre, Editorial Board Member, Torres-Suárez, Ana Isabel, Editorial Board Member, Włodarczyk, Jakub, Editorial Board Member, Yeong, Joe Poh Sheng, Editorial Board Member, Toscano, Marta A., Editorial Board Member, Wong, Tak-Wah, Editorial Board Member, Yin, Jun, Editorial Board Member, Yu, Bin, Editorial Board Member, and Hamdy, Nadia M., Editorial Board Member
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- 2024
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48. Addressing the Social Determinants of Mental Health to Achieve Equitable Clinical Care, Research, Education, and Public Policy
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Gordon-Achebe, Kimberly, Rosenfield, Paul, Roary, Mary, Malaspina, Dolores, Lu, Francis, Thompson, Kenneth, Tasman, Allan, Ndetei, David, Section editor, Feldman, Jacqueline Maus, Section editor, Tasman, Allan, editor, Riba, Michelle B., editor, Alarcón, Renato D., editor, Alfonso, César A., editor, Kanba, Shigenobu, editor, Lecic-Tosevski, Dusica, editor, Ndetei, David M., editor, Ng, Chee H., editor, and Schulze, Thomas G., editor
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- 2024
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49. Variations on the Great Refusal via Dante and Whitehead
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Malaspina, Cécile, primary
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- 2024
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50. Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysisResearch in context
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Michael Benatar, Eric A. Macklin, Andrea Malaspina, Mary-Louise Rogers, Eran Hornstein, Vittoria Lombardi, Danielle Renfrey, Stephanie Shepheard, Iddo Magen, Yahel Cohen, Volkan Granit, Jeffrey M. Statland, Jeannine M. Heckmann, Rosa Rademakers, Caroline A. McHutchison, Leonard Petrucelli, Corey T. McMillan, Joanne Wuu, Lauren Elman, John Ravits, Jonathan Katz, Jaya Trivedi, Andrea Swenson, Ted M. Burns, James Caress, Carlayne Jackson, Samuel Maiser, Erik P. Pioro, and Yuen So
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Prognostic biomarkers ,Context-of-use ,ALS clinical trials ,Neurofilament ,Medicine ,Medicine (General) ,R5-920 - Abstract
Summary: Background: With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among the prevailing clinical and biochemical markers have real value, and how they can be optimally used. Methods: A subset of patients with ALS recruited through the multi-center Phenotype-Genotype-Biomarker study (clinicaltrials.gov: NCT02327845) was identified as “trial-like” based on meeting common trial eligibility criteria. Clinical phenotyping was performed by evaluators trained in relevant assessments. Serum neurofilament light (NfL) and phosphorylated neurofilament heavy (pNfH), urinary p75ECD, plasma microRNA-181, and an array of biochemical and clinical measures were evaluated for their prognostic value. Associations with functional progression were estimated by random-slopes mixed models of ALS functional rating scale-revised (ALSFRS-R) score. Associations with survival were estimated by log-rank test and Cox proportional hazards regression. Potential sample size savings from adjusting for given biomarkers in a hypothetical trial were estimated. Findings: Baseline serum NfL is a powerful prognostic biomarker, predicting survival and ALSFRS-R rate of decline. Serum NfL 100 pg/mL correspond to future ALSFRS-R slopes of ∼0.5 and ∼1.5 points/month, respectively. Serum NfL also adds value to the best available clinical predictors, encapsulated by the European Network to Cure ALS (ENCALS) predictor score. In models of functional decline, the addition of NfL yields ∼25% sample size saving above those achieved by inclusion of either clinical predictors or ENCALS score alone. The prognostic value of serum pNfH, urinary p75ECD, and plasma miR-181ab is more limited. Interpretation: Among the multitude of biomarkers considered, only blood NfL adds value to the ENCALS prediction model and should be incorporated into analysis plans for all ongoing and future ALS trials. Defined thresholds of NfL might also be used in trial design, for enrichment or stratified randomisation, to improve trial efficiency. Funding: NIH (U01-NS107027, U54-NS092091). ALSA (16-TACL-242).
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- 2024
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