1. Decrease in opioid and intra-articular corticosteroid burden after intra-articular hyaluronic acid for knee osteoarthritis treatment
- Author
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Niazi, Faizan, Ong, Kevin L, Kidd, Vasco Deon, Lau, Edmund, Kurtz, Steven M, Dysart, Stanley H, and Malanga, Gerard
- Subjects
Pharmacology and Pharmaceutical Sciences ,Biomedical and Clinical Sciences ,Chronic Pain ,Clinical Research ,Pain Research ,Arthritis ,6.1 Pharmaceuticals ,Evaluation of treatments and therapeutic interventions ,Good Health and Well Being ,Adrenal Cortex Hormones ,Analgesics ,Opioid ,Arthroplasty ,Replacement ,Knee ,Humans ,Hyaluronic Acid ,Injections ,Intra-Articular ,Osteoarthritis ,Knee ,hyaluronic acid ,intra-articular corticosteroids ,knee arthroplasty ,knee osteoarthritis ,opioids ,Clinical sciences - Abstract
Aim: We studied changes in opioid prescriptions and corticosteroid injection use for knee osteoarthritis patients before and after intra-articular hyaluronic acid (HA) use and opioid prescriptions before and after knee arthroplasty (KA). Materials & methods: A total of 1,017,578 knee osteoarthritis members were ascertained from a commercial claims database (Health Intelligence Company LLC, IL, USA) using ICD9/ICD10 diagnosis codes. Results: Eighty two percent of HA patients did not fill opioid prescriptions postinjection, with 54% of opioid users discontinuing fills. Two-thirds of KA patients filled opioid prescriptions within 6 months postsurgery, with 78% of opioid users continuing fills and 62% of nonusers initiating use. Conclusion: Alternative therapies, such as HA, that reduce opioid use may alleviate opioid addiction risks for KA patients who use opioids in the pre- and postoperative periods.
- Published
- 2020