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164 results on '"Maksymowicz, Krzysztof"'

2. Model of Lung Cancer Progression and Metastasis—Need for a Delay

Author

Psiuk-Maksymowicz, Krzysztof, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Strumiłło, Paweł, editor, Klepaczko, Artur, editor, Strzelecki, Michał, editor, and Bociąga, Dorota, editor

Published
2024
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4. Finding the Time-Dependent Virus Transmission Intensity via Gradient Method and Adjoint Sensitivity Analysis

Author

Łakomiec, Krzysztof, Wilk, Agata, Psiuk-Maksymowicz, Krzysztof, Fujarewicz, Krzysztof, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Pietka, Ewa, editor, Badura, Pawel, editor, Kawa, Jacek, editor, and Wieclawek, Wojciech, editor

Published
2022
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5. A Framework for Modeling and Efficacy Evaluation of Treatment of Cancer with Metastasis

Author

Smieja, Jaroslaw, Psiuk-Maksymowicz, Krzysztof, Swierniak, Andrzej, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Pijanowska, Dorota G., editor, Zieliński, Krzysztof, editor, and Liebert, Adam, editor

Published
2022
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8. BioTest - Remote Platform for Hypothesis Testing and Analysis of Biomedical Data

Author

Psiuk-Maksymowicz, Krzysztof, Jaksik, Roman, Placzek, Aleksander, Gruca, Aleksandra, Student, Sebastian, Borys, Damian, Mrozek, Dariusz, Fujarewicz, Krzysztof, Swierniak, Andrzej, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Korbicz, Józef, editor, Maniewski, Roman, editor, Patan, Krzysztof, editor, and Kowal, Marek, editor

Published
2020
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10. Rigid and Non-rigid Registration Algorithm Evaluation in MRI for Breast Cancer Therapy Monitoring

Author

Bzowski, Paweł, Danch-Wierzchowska, Marta, Psiuk-Maksymowicz, Krzysztof, Panek, Rafał, Borys, Damian, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Pietka, Ewa, editor, Badura, Pawel, editor, Kawa, Jacek, editor, and Wieclawek, Wojciech, editor

Published
2019
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11. Identification of Factors that Affect Reproducibility of Mutation Calling Methods in Data Originating from the Next-Generation Sequencing

Author

Jaksik, Roman, Psiuk-Maksymowicz, Krzysztof, Swierniak, Andrzej, Barbosa, Simone Diniz Junqueira, Series Editor, Filipe, Joaquim, Series Editor, Kotenko, Igor, Series Editor, Sivalingam, Krishna M., Series Editor, Washio, Takashi, Series Editor, Yuan, Junsong, Series Editor, Zhou, Lizhu, Series Editor, Czachórski, Tadeusz, editor, Gelenbe, Erol, editor, Grochla, Krzysztof, editor, and Lent, Ricardo, editor

Published
2018
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12. Functional Interpretation of Gene Sets: Semantic-Based Clustering of Gene Ontology Terms on the BioTest Platform

Author

Gruca, Aleksandra, Jaksik, Roman, Psiuk-Maksymowicz, Krzysztof, Kacprzyk, Janusz, Series editor, Pal, Nikhil R., Advisory editor, Bello Perez, Rafael, Advisory editor, Corchado, Emilio S., Advisory editor, Hagras, Hani, Advisory editor, Kóczy, László T., Advisory editor, Kreinovich, Vladik, Advisory editor, Lin, Chin-Teng, Advisory editor, Lu, Jie, Advisory editor, Melin, Patricia, Advisory editor, Nedjah, Nadia, Advisory editor, Nguyen, Ngoc Thanh, Advisory editor, Wang, Jun, Advisory editor, Gruca, Aleksandra, editor, Czachórski, Tadeusz, editor, Harezlak, Katarzyna, editor, Kozielski, Stanisław, editor, and Piotrowska, Agnieszka, editor

Published
2018
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13. Introduction

Author

Świerniak, Andrzej, Kimmel, Marek, Smieja, Jaroslaw, Puszynski, Krzysztof, Psiuk-Maksymowicz, Krzysztof, Świerniak, Andrzej, Kimmel, Marek, Smieja, Jaroslaw, Puszynski, Krzysztof, and Psiuk-Maksymowicz, Krzysztof

Published
2016
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14. Model Identification and Parameter Estimation

Author

Świerniak, Andrzej, Kimmel, Marek, Smieja, Jaroslaw, Puszynski, Krzysztof, Psiuk-Maksymowicz, Krzysztof, Świerniak, Andrzej, Kimmel, Marek, Smieja, Jaroslaw, Puszynski, Krzysztof, and Psiuk-Maksymowicz, Krzysztof

Published
2016
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18. Cell Cycle as an Object of Control

Author

Świerniak, Andrzej, Kimmel, Marek, Smieja, Jaroslaw, Puszynski, Krzysztof, Psiuk-Maksymowicz, Krzysztof, Świerniak, Andrzej, Kimmel, Marek, Smieja, Jaroslaw, Puszynski, Krzysztof, and Psiuk-Maksymowicz, Krzysztof

Published
2016
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20. Scalability of a Genomic Data Analysis in the BioTest Platform

Author

Psiuk-Maksymowicz, Krzysztof, Mrozek, Dariusz, Jaksik, Roman, Borys, Damian, Fujarewicz, Krzysztof, Swierniak, Andrzej, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Nguyen, Ngoc Thanh, editor, Tojo, Satoshi, editor, Nguyen, Le Minh, editor, and Trawiński, Bogdan, editor

Published
2017
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22. A Holistic Approach to Testing Biomedical Hypotheses and Analysis of Biomedical Data

Author

Psiuk-Maksymowicz, Krzysztof, Płaczek, Aleksander, Jaksik, Roman, Student, Sebastian, Borys, Damian, Mrozek, Dariusz, Fujarewicz, Krzysztof, Świerniak, Andrzej, Diniz Junqueira Barbosa, Simone, Series editor, Chen, Phoebe, Series editor, Du, Xiaoyong, Series editor, Filipe, Joaquim, Series editor, Kara, Orhun, Series editor, Liu, Ting, Series editor, Kotenko, Igor, Series editor, Sivalingam, Krishna M., Series editor, Washio, Takashi, Series editor, Kozielski, Stanisław, editor, Mrozek, Dariusz, editor, Kasprowski, Paweł, editor, Małysiak-Mrozek, Bożena, editor, and Kostrzewa, Daniel, editor

Published
2016
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23. Integrated System Supporting Research on Environment Related Cancers

Author

Bensz, Wojciech, Borys, Damian, Fujarewicz, Krzysztof, Herok, Kinga, Jaksik, Roman, Krasucki, Marcin, Kurczyk, Agata, Matusik, Kamil, Mrozek, Dariusz, Ochab, Magdalena, Pacholczyk, Marcin, Pieter, Justyna, Puszynski, Krzysztof, Psiuk-Maksymowicz, Krzysztof, Student, Sebastian, Swierniak, Andrzej, Smieja, Jaroslaw, Kacprzyk, Janusz, Series editor, Król, Dariusz, editor, Madeyski, Lech, editor, and Nguyen, Ngoc Thanh, editor

Published
2016
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27. Association between Leukocyte Cell-Derived Chemotaxin 2 and Metabolic and Renal Diseases in a Geriatric Population: A Pilot Study.

Author

Kuzan, Aleksandra, Maksymowicz, Krzysztof, Królewicz, Emilia, Lindner-Pawłowicz, Karolina, Zatyka, Piotr, Wojnicz, Piotr, Nowaczyński, Maciej, Słomczyński, Adam, and Sobieszczańska, Małgorzata

Subjects
*ATHEROSCLEROTIC plaque, *METABOLIC disorders, *KIDNEY diseases, *KIDNEY physiology, *LEUCOCYTES, *LIVER proteins
Abstract

LECT2 is not a routine diagnostic marker for any disease, but it has been associated with many pathologies, including systemic amyloidosis, rheumatoid arthritis, diabetes, atherosclerosis, and metabolic syndrome. With human aortic sections (n = 22) and sera from geriatric subjects (n = 79), we analyzed the relationships that could be observed between this protein and other parameters related to metabolic diseases. As a result, we observed a relatively high (r~0.8, p < 0.05) positive correlation between SRA and LECT2 and a negative correlation between EGFR and LECT2 (r~−0.4, p < 0.05). We observed LECT2 expression in macrophages, myocytes, and other aortic cells, with a tendency to be overexpressed in developed atherosclerotic plaques. We conclude that LECT2 exerts its chemotactic effects not only as a protein synthesized in the liver and secreted and circulating in the blood but also as a locally expressed protein within atherosclerotic plaque development. The LECT2-EGFR correlation suggests an association of this protein with loss of normal renal function. This fact can be associated with LECT2 amyloidosis, although it should be verified whether in the geriatric population there is indeed a widespread accumulation of LECT2 with the progression of aging or whether it is rather a marker of general deterioration of renal function. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Potential participation of glycation and anabolic androgenic steroids in young man's aneurysm development: case report.

Author

Kuzan, Aleksandra and Maksymowicz, Krzysztof

Subjects
THORACOABDOMINAL aortic aneurysms, IMMUNOHISTOCHEMISTRY, AUTOPSY, FLUORESCENCE spectroscopy, CELL receptors, ADVANCED glycation end-products, AORTIC rupture, LYMPHOCYTES, ENZYME-linked immunosorbent assay, ANABOLIC steroids, HIGH density lipoproteins, ADULTS
Abstract

A young patient was found dead due to rupture of the thoracoabdominal aortic aneurysm. Physical phenotype suggested anabolic androgenic steroids use. The research hypothesis was that intense glycation and anabolic steroids may contribute to the remodeling of the artery to develop an aneurysm. Immunoenzymatic methods (immunochistochemistry and ELISA) and spectrofluorimetry were used. Immunohistochemical reaction shows the presence of advanced glycation end products (AGE). Receptors for AGE: scavenger receptor A and B and receptor for advanced glycation end products (RAGE) are located mainly in the adventitia in lymphocytes. Comparing the artery content of AGE and AGE receptors from the group of scavenging receptors, we find that AGE and SR-A are relatively low, and the content of SR-B – a protein that also binds high-density lipoprotein (HDL) – is relatively high. The results indicate that the patient had not intensified glycation. The analysis of the literature on the subject shows data that anabolic steroids could even inhibit the development of an aneurysm. Thus, we reject the research hypothesis that steroids and intensified glycation could be the cause of death here, and we conclude that it is necessary to study the content of AGE and their receptors on a greater number of aortic sections from patients with aneurysm, including patients with diabetes. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Numerical modeling of blood flow in bifurcation and trifurcation geometries use of different boundary conditions

Author

Bernyś, Michał, Melka, Bartłomiej, Gracka, Maria, Ostrowski, Ziemowit, Rojczyk, Marek, Psiuk-Maksymowicz, Krzysztof, Borys, Damian, Wasilewski, Jarosław, Głowacki, Jan, and Białecki, Ryszard

Subjects
onkologia obliczeniowa, naczynia wieńcowe, bifurkacja, przepływ krwi, obliczeniowa mechanika płynów, trifurkacja, medycyna spersonalizowana, modelowanie numeryczne
Published
2023
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34. Postępy w onkologii obliczeniowej i spersonalizowanej medycynie. T. 2, Wyzwania przyszłości

Author

Adamiec-Organiściok, Małgorzata, Bartnicka, Joanna, Bernyś, Michał, Białecki, Ryszard, Bojar, Piotr, Borys, Damian, Bugdol, Monika, Choiński, Dariusz, Frąckiewicz, Mariusz, Gil, Jarosław, Głowacki, Jan, Gogler-Pigłowska, Agnieszka, Gracka, Maria, Herrera, Cristina, Hudecki, Andrzej, Hybiak, Jolanta, Jankowska, Kornelia, Jędrzejowski, Maksymilian, Juszczyk, Jan, Kabiesz, Patrycja, Kalisz, Seweryn, Kania, Mateusz, Kipsang, Benard, Kostka, Daria, Kowol, Karolina, Krukiewicz, Katarzyna, Langer-Macioł, Hanna, Lucińska, Kinga, Łos, Marek J., Majchrzak, Ewa, Marczyk, Michał, Melka, Bartłomiej, Mleczko, Katarzyna, Ostrowski, Ziemowit, Patel, Taral, Peters, Harm, Piętka, Ewa, Płonka, Wiktoria, Polańska, Joanna, Polański, Andrzej, Prażuch, Wojciech, Psiuk-Maksymowicz, Krzysztof, Pyciński, Bartłomiej, Rojczyk, Marek, Rutto, Wesley Chebii, San Martin Valenzuela, Constanza, Sieradzka, Katarzyna, Sikora, Wojciech, Skonieczna, Magdalena, Skorupa, Małgorzata, Skupin, Piotr, Socha, Marek, Sojka, Damian, Staśczak, Alicja, Strózik, Barbara, Student, Sebastian, Suwalska, Aleksandra, Szymiczek, Krzysztof, Ścieglińska, Dorota, Śliwińska, Wiktoria, Tobiasz, Joanna, Wasilewski, Jarosław, Wencel, Przemysław, Widzisz, Karolina, Wilczek, Piotr, Ziętkiewicz, Agnieszka, POLCOVID Study Group, Krukiewicz, Katarzyna. Red., Marczyk, Michał. Red., Bugdol, Monika. Red., Bajkacz, Sylwia. Red., Ostrowski, Ziemowit. Red., and Polańska, Joanna. Red. serii

Subjects
bioinformatyka, onkologia obliczeniowa, medycyna spersonalizowana, modelowanie numeryczne, e-learning, biomateriały
Published
2023
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39. Integrated System Supporting Research on Environment Related Cancers

Author

Bensz, Wojciech, primary, Borys, Damian, additional, Fujarewicz, Krzysztof, additional, Herok, Kinga, additional, Jaksik, Roman, additional, Krasucki, Marcin, additional, Kurczyk, Agata, additional, Matusik, Kamil, additional, Mrozek, Dariusz, additional, Ochab, Magdalena, additional, Pacholczyk, Marcin, additional, Pieter, Justyna, additional, Puszynski, Krzysztof, additional, Psiuk-Maksymowicz, Krzysztof, additional, Student, Sebastian, additional, Swierniak, Andrzej, additional, and Smieja, Jaroslaw, additional

Published
2016
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41. Modelowanie numeryczne przepływu krwi w geometriach bifurkacji i trifurkacji z wykorzystaniem różnych warunków brzegowych

Author

Bernyś, Michał, Melka, Bartłomiej, Gracka, Maria, Ostrowski, Ziemowit, Rojczyk, Marek, Psiuk-Maksymowicz, Krzysztof, Borys, Damian, Wasilewski, Jarosław, Głowacki, Jan, Białecki, Ryszard, Krukiewicz, Katarzyna. Red., Bajkacz, Sylwia. Red., Marczyk, Michał. Red., Ostrowski, Ziemowit. Red., Bugdol, Monika. Red., and Polańska, Joanna. Red. serii

Subjects
onkologia obliczeniowa, naczynia wieńcowe, bifurkacja, przepływ krwi, obliczeniowa mechanika płynów, trifurkacja, medycyna spersonalizowana, modelowanie numeryczne
Published
2022

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