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Introduction: Presently, bariatric surgery is considered the most compelling treatment modality for morbid obesity patient and one of the most effective procedures. The study aimed to identify the prevalence and determinants of patients’ compliance to the recommended vitamin and mineral supplements and to identify the prevalence and determinants of post-bariatric surgery nutritional deficiencies in King Fahad General Hospital in Jeddah city so as to improve the patients’ health. Materials and Methods: This is a cross-sectional study wherein a validated questionnaire was used to collect data and were encoded and analyzed using IBM SPSS version 23, (IBD Corp., Armonk, NY). Results: The findings of the study showed that nutritional deficiency is more likely to happen to female gender who is working. The study also revealed that deficiencies are common in HB, Vit D, Vit B12, calcium, iron and folate. The longer the period of intensive fluid taken following surgery increases the risk of vitamin deficiency. Furthermore, there’s low compliance to vitamins and supplements and patients who underwent bariatric surgery only become adherent to vitamins/minerals when they discover complications. Conclusion: This study concluded that there are various factors causing and affecting nutritional deficiencies preoperatively and postoperatively such as gender, work status, complications, and vitamins and supplements compliance. Overall, the present study concluded that it is imperative for the patients to adhere to vitamins and supplements intake according to the recommendation of the clinicians and dieticians. Keywords: Obesity, Bariatric surgery, Nutritional deficiency.