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BACKGROUND:Polymeric immunoglobulin receptor (pIgR) transport of secretory immunoglobulin A (SIgA) to mucosal surfaces is thought to promote gut integrity and immunity to Salmonella enterica serovar Typhimurium (S. Typhimurium), an invasive pathogen in mice. To elucidate potential mechanisms, we assessed intestinal barrier function and both oral and systemic S. Typhimurium virulence in pIgR knockout (KO) and wildtype (WT) mice. METHODS:In uninfected animals, we harvested jejunal segments for Ussing chamber analyses of transepithelial resistance (TER); mesenteric lymph nodes (mLN) for bacterial culture; and serum and stool for IgA. Separately, we infected mice either orally or intravenously (IV) with S. Typhimurium to compare colonization, tissue dynamics, and inflammation between KOs and WTs. RESULTS:Uninfected KOs displayed decreased TER and dramatically increased serum IgA and decreased fecal IgA vs. WT; however, KO mLNs yielded fewer bacterial counts. Remarkably, WTs challenged orally with S. Typhimurium exhibited increased splenomegaly, tissue colonization, and pro-inflammatory cytokines vs. pIgR KOs, which showed increased survival following either oral or IV infection. CONCLUSIONS:Absence of pIgR compromises gut integrity but does not exacerbate bacterial translocation nor S. Typhimurium infection. These findings raise the possibility that immune adaptation to increased gut permeability and elevated serum IgA in the setting of SIgA deficiency provides compensatory protection against invasive gut pathogens.

El presente artículo explora las posturas enfrentadas sobre el aborto en México, mediante el análisis de contenido de textos y pronunciamientos publicados recientemente y emitidos por actores colectivos nacionales y sus aliados o institutos internacionales. A partir del estudio de las diferencias de significación del aborto en los discursos en pugna en México hoy en día, no solo se pretende identificar las lógicas discursivas diferenciales que los sustentan, sino también situar esta disputa en el contexto de la era actual de transición entre dos modelos estructurales-tecnológicos capitalistas: la modernidad industrial y el postindustrialismo, y de tal manera argumentar que el aborto es emblemático de una contienda contemporánea mayor por la propia naturaleza del Estado y su relación con la religión. En este sentido, el enfrentamiento sobre el aborto es también una disputa por el proyecto societario. This article explores the opposing positions on abortion in Mexico, using the content analysis of texts and pronouncements recently published and issued by domestic collective actors and their allies or international institutes. From the study of the differences of significance of abortion in rivaled speeches in Mexico today, not only does this article seek to identify the distinguishing discursive logic that supports them, but also put this dispute in the context of the current era of transition between two capitalist structural-technological models: industrial modernity and post-industrialism, and so argue that abortion is emblematic of a larger contemporary race for the nature of the state and its relationship with religion. As such, it represents a clash over the societal project itself. O presente artigo explora as posturas enfrentadas sobre o aborto no México, mediante análise de conteúdo de textos e pronunciamentos publicados recentemente e emitidos por atores coletivos nacionais e seus aliados ou institutos internacionais. A partir do estudo das diferenças de significação do aborto nos discursos concorrentes no México de hoje, não apenas objetiva-se identificar as lógicas discursivas diferenciais que os sustentam, mas também colocar tal disputa no contexto da era atual de transição entre dois modelos estruturais-tecnológicos capitalistas: a modernidade industrial e o pós-industrialismo, e de tal forma argumentar que o aborto é emblemático de uma contenda contemporânea maior pela própria natureza do Estado e seu relacionamento com a religião. Neste sentido, o confronto sobre aborto é também uma disputa pelo projeto societário.

This research work is a sustained attempt to scientifically interpret the Meditative Guidance of the Divine Omdasji Sound Meditation (SR0000398348 dated 2006-09-13, United States Copyright Office) renowned to bring peace and calm to the meditating human subject. It is the outcome of inspiration dawned on the authors to scientifically investigate such phenomena connected with the Divine Omdasji Sound Meditation. The Divine Omdasji Sound Meditation has been found to have many properties that Science can explain. Signal Processing techniques accompanied with BioPhotonic Communication, Meditative Consciousness & BioAcoustic Fields and Multiple Phase Locked Loops are used to analyze the Divine Omdasji Sound Meditation. Meditative guidance characteristics for multiple subjects at various levels are exhibited by the inference from the experimental results including a unique phenomenon of guided dual consciousness state awareness in meditation. Further analysis and inference indicates that the Divine Omdasji Sound Meditation can be used as a cure for mental depression, sleep disorders, anxiety, drug addiction and loss of immunity. Analysis indicates that the Divine Omdasji Sound Meditation is a Universal Cure for Human Diseases. Further, psychological acceptance of the Divine Omdasji Sound Meditation as a Universal Cure for Human Diseases is analysed. Keywords: Divine Omdasji Sound Meditation, Meditation, Meditative Guidance, Dual Consciousness state, Awareness, Cure, Mental Depression, Sleep Disorders, Anxiety, Drug addiction and loss of immunity, Psychological Acceptance URL: https://www.ijbspt.org/papers-published/ijbspt-2010-volume-2-issue-2

This research work is a sustained attempt to scientifically interpret the Meditative Guidance of the Divine Omdasji Sound Meditation (SR0000398348 dated 2006-09-13, United States Copyright Office) renowned to bring peace and calm to the meditating human subject. It is the outcome of inspiration dawned on the authors to scientifically investigate such phenomena connected with the Divine Omdasji Sound Meditation. The Divine Omdasji Sound Meditation has been found to have many properties that Science can explain. Signal Processing techniques are used to perform Spectral Analysis of the Divine Omdasji Sound Meditation. The results indicate presence of significant patterns of low decibel power infrasound in the Divine Omdasji Sound Meditation. This paper proposes interpretations to this and meditative guidance characteristics inferred from the experimental results. This work concentrates on presenting a retro-analysis of the explanation to the mystic phenomena of meditative guidance to multiple subjects using biophotonic communication and bioacoustic fields operating on the principles of the multiple phase locked loop. Keywords: Divine Omdasji Sound Meditation, Meditation, Meditative Guidance, Infrasound, Low power, Spectral Analysis, Consciousness Communications, BioAcoustic Fields, BioPhotonic Communication URL: https://www.ijbspt.org/papers-published/ijbspt-2009-volume-1-issue-1

45-75 trimestral