1. The 5-year pre- and post-hospitalization treated prevalence of mental disorders and psychotropic medication use in critically ill patients: a Canadian population-based study
- Author
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William D. Leslie, Ruth Ann Marrie, Kendiss Olafson, Sarvesh Logsetty, Christine Leong, Laurence Y. Katz, Murray W. Enns, Marcus Blouw, Charles N. Bernstein, Dan Chateau, Renée El-Gabalawy, Murray B. Stein, Sophia Sweatman, James M. Bolton, Yao Nie, Tracie O. Afifi, Jitender Sareen, O. Joseph Bienvenu, Maia S. Kredentser, and Natalie Mota
- Subjects
medicine.medical_specialty ,education.field_of_study ,business.industry ,Population ,Critical Care and Intensive Care Medicine ,Intensive care unit ,3. Good health ,030227 psychiatry ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Prevalence of mental disorders ,Mood ,law ,Internal medicine ,Anesthesiology ,Epidemiology ,medicine ,Anxiety ,030212 general & internal medicine ,medicine.symptom ,Medical prescription ,education ,business - Abstract
The interplay between critical illness and mental disorders is poorly understood. The purpose of this study is to measure both the treated prevalence of mental disorders and psychotropic medication use before and after hospitalization and the impact of intensive care unit (ICU) admission on these outcomes. Using a population-based administrative database in Manitoba, Canada, 49,439 ICU patients admitted between 2000 and 2012 were compared to two matched comparison groups (hospitalized; n = 146,968 and general population; n = 141,937). Treated prevalence of mental disorders and psychotropic medication prescriptions were measured in the 5-year periods before and after the hospitalization. Multivariable models compared adjusted prevalence ratios (APRs) between populations. The 5-year treated mental disorder prevalence in the ICU population increased from 41.5% pre-hospitalization to 55.6% post-hospitalization. Compared to non-ICU hospitalized patients, the adjusted treated mental disorder prevalence in ICU patients was lower prior to hospitalization (1-year APR 0.94, 95% CI 0.92–0.97, p
- Published
- 2021
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