Search

Your search keyword '"Mahraoui C"' showing total 106 results
Start Over Author "Mahraoui C"
106 results on '"Mahraoui C"'

16. La fibroscopie bronchique chez l’enfant: Expertise des centres français de pneumologie pédiatrique

Author

Le Roux, P., de Blic, J., Albertini, M., Bellon, G., Body, G., Brémont, F., Caurier, B., Chomienne, F., Counil, F., Dalphin, L., David, V., Delacourt, C., Deneuville, E., Derelle, J., Deschildre, A., Donato, L., Dubus, J.C., Fayon, M., Garcia, J., Heuzé, L., Houzel, A., Just, J., Labbé, A., Lesbros, D., Mahraoui, C., Malfroot, A., Marguet, C., Monrigal, P., Pautard, J.C., Pin, I., Rayet, I., Sardet, A., Scalbert, M., Siret, D., and Troadec, C.

Published
2004
Full Text
View/download PDF

20. Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco.

Author

Annamalay, A., Jroundi, I., Bizzintino, J., Khoo, S., Zhang, Guicheng, Lehmann, D., Laing, I., Gern, J., Goldblatt, J., Mahraoui, C., Benmessaoud, R., Moraleda, C., Bassat, Q., Le Souëf, P., Annamalay, A., Jroundi, I., Bizzintino, J., Khoo, S., Zhang, Guicheng, Lehmann, D., Laing, I., Gern, J., Goldblatt, J., Mahraoui, C., Benmessaoud, R., Moraleda, C., Bassat, Q., and Le Souëf, P.

Abstract

Human rhinovirus (RV) is commonly associated with severe acute lower respiratory infections (ALRI) in children. We aimed to describe the distribution of RV species and associations between RV species and clinical features in children hospitalized with clinically severe pneumonia (CSP) in Morocco. Nasopharyngeal aspirates (NPAs) were collected from 700 children, 2-59 months of age, admitted with CSP to the Hôpital d'Enfants de Rabat in Morocco. At least one respiratory virus was identified in 92% of children, of which RV was the most common (53%). PCR assays, sequencing, and phylogenetic tree analyses were carried out on 183 RV-positive NPAs to determine RV species and genotypes. Of 157 successfully genotyped NPAs, 60 (38.2%) were RV-A, 8 (5.1%) were RV-B, and 89 (56.7%) were RV-C. Wheezing and cyanosis were more common in RV-C-positive than RV-A-positive children (80.9% vs. 56.7%; P?=?0.001 for wheezing and 10.1% vs. 0%; P?=?0.011 for cyanosis). Physician's discharge diagnosis of pneumonia was more frequent among RV-A-positive (40.0%) than RV-C-positive children (20.2%; P?=?0.009). RV-A and RV-C showed distinct seasonal patterns. Our findings suggest that RV-C is associated with wheezing illness while RV-A is associated with pneumonia. J. Med. Virol. 89:582-588, 2017. © 2016 Wiley Periodicals, Inc.

Published
2017

21. Feverish Agitation Unveiling a Poly Poisoning in Young Children

Author

El Hafidi, Badrane N, Benbrahim F, Mahraoui C, Zouiri G, MA Radouani, A Assermouh, and S. Benchekroun

Subjects
Pediatrics, medicine.medical_specialty, Neonatal sepsis, business.industry, medicine.disease, Irritability, Hospice and palliative medicine, Adolescent medicine, Pediatric emergency medicine, medicine, Ingestion, Pediatric ophthalmology, medicine.symptom, business, Pediatric gastroenterology
Abstract

The use of plants is widespread with traditional Moroccan medicine occasionally resulting in poisoning that can be sometimes be fatal, especially in children. The toxicity of medicinal plants and their chemical interactions are mostly unknown by many who use these topical/oral mixtures. We report the case of 4 year old boy, hospitalized in the department of Infectious Diseases P1 at the Children's Hospital of Rabat for 'feverish agitation' (fever and central nervous system irritability) after inhalation of Peganum harmala, ingestion of Chenopodium and nasal application of cade oil. The laboratory tests concluded renal and hepatic failure. The clinical condition improved after 36 hours, with renal and hepatic failure resolving after 3 to 6 days.

Published
2014
Full Text
View/download PDF

22. LA TOXOPLASMOSE CONGENITALE

Author

BENJELLOUN DAKHAMA, BS., EL HARIM ROUDIES, L., REGRAGUI, A., ASSERMOUH, A., MAHRAOUI, C., JORIO, M., and EL MALKI TAZI, A.

Subjects
Toxoplasmose congénitale, diagnostic prénatal, sérologie, pyriméthamine sulfamides
Abstract

Nous rapportons 4 cas de toxoplasmose congénitale colligés dans le service de pédiatrie infectieuse. Un traitement prénatal par la spiramycine a été préconisé chez deux patients après séroconversion maternelle. A la naissance deux nourissons accusaient une forme clinique grave, et deux autres une forme clinique pauci-symptomatique. Un nourisson a été hors de toute ressource thérapeutique. Un traitement associatif a été prescrit chez 3 nourissons. L’évolution a été marquée par des séquelles neuro-oculaires dans un cas, une choriorétinite séquellaire dans un autre cas. Un seul enfant a évolué favorablement., Maroc Médical, Vol. 22, No 3 (2000)

Published
2013
Full Text
View/download PDF

24. A comparison of human metapneumovirus and respiratory syncytial virus WHO-defined severe pneumonia in Moroccan children

Author

JROUNDI, I., primary, MAHRAOUI, C., additional, BENMESSAOUD, R., additional, MORALEDA, C., additional, TLIGUI, H., additional, SEFFAR, M., additional, KETTANI, S. E. C. EL, additional, BENJELLOUN, B. S., additional, CHAACHO, S., additional, MUÑOZ-ALMAGRO, C., additional, RUIZ, J., additional, ALONSO, P. L., additional, and BASSAT, Q., additional

Published
2015
Full Text
View/download PDF

27. Prescription des antibiotiques avant et durant l’hospitalisation chez des enfants âgés de moins de 5ans admis à l’hôpital pédiatrique universitaire de Rabat au Maroc pour pneumonie clinique grave

Author

Jroundi, I., primary, Benmessaoud, R., additional, Mahraoui, C., additional, Moraleda, C., additional, Tligui, H., additional, Seffar, M., additional, Benjelloun, B.S., additional, Vila, J., additional, Ruiz, J., additional, Alonso, P.L., additional, and Bassat, Q., additional

Published
2014
Full Text
View/download PDF

32. The Epidemiology and Aetiology of Infections in Children Admitted with Clinical Severe Pneumonia to a University Hospital in Rabat, Morocco

Author

Jroundi, I., primary, Mahraoui, C., additional, Benmessaoud, R., additional, Moraleda, C., additional, Tligui, H., additional, Seffar, M., additional, Kettani, S. C., additional, Benjelloun, B. S., additional, Chaacho, S., additional, Maaroufi, A., additional, Hayes, E. B., additional, Alvarez-Martinez, M. J., additional, Munoz-Almagro, C., additional, Ruiz, J., additional, Alonso, P. L., additional, and Bassat, Q., additional

Published
2014
Full Text
View/download PDF

45. Brain abscess in children

Author

Benjelloun-Dakhama, B.S., Madani, A. El, Hassani, A. El, Mahraoui, C., Benchekroun, S., Jorio, M., Harim, L. El, and Malki-Tazi, A. El

Published
1999
Full Text
View/download PDF

46. Streptococcus pneumoniaecarriage among healthy and sick paediatric patients before the generalized implementation of the 13-valent pneumococcal vaccine in Morocco, 2010–2011

Author

Jroundi, I., Mahraoui, C., Benmessaoud, R., Moraleda, C., and Bassat, Q.

Abstract

Nasopharyngeal carriage studies provide insights into the local prevalence of circulating pneumococcal serotypes. These data are critical to vaccination monitoring, as they allow for the prediction and assessment of impact. Very little data are available on the carriage of pneumococcal serotypes in Morocco. The aim of the study was to describe the prevalence of Streptococcus pneumoniae carriage and serotype distribution among healthy and sick pediatric patients with ages ranging from 2 to 59 months.

Published
2018
Full Text
View/download PDF

47. Pertussis outbreak in children hospitalized in Rabat (Morocco).

Author

Bennai RM, Zouaki A, El Amin G, Rahani A, Zirar J, Seffar M, Soully K, Mahraoui C, and Kabbaj H

Subjects
Humans, Infant, Retrospective Studies, Male, Female, Child, Preschool, Morocco epidemiology, Child, Hospitalization statistics & numerical data, Infant, Newborn, Prevalence, Adolescent, Bordetella parapertussis genetics, Bordetella parapertussis isolation & purification, Whooping Cough epidemiology, Whooping Cough microbiology, Disease Outbreaks, Bordetella pertussis genetics, Bordetella pertussis isolation & purification
Abstract

Introduction: Cyclical pertussis epidemics primarily affect young infants. This study aims to estimate pertussis prevalence during the ongoing 2023 outbreak at our institution, focusing on affected age groups and clinical presentations., Materiel and Methods: This retrospective study includes patients admitted to Rabat University Hospital Center from 1st January 2021 to 30th June 2023. Symptomatic patients underwent Multiplex Respiratory Panel PCR testing for respiratory infections. The analysis included cases where RT-PCR identified Bordetella spp., with data analysed using SPSS 15.0., Results: Pertussis cases sharply increased from December 2022, constituting 85.4 % of positive samples. Most cases (78.2 %) occurred in infants under 3 months, presenting symptoms such as coughing (94.5 %) and dyspnoea (94.5 %). Pertussis was suspected in 60 % of RT-PCR confirmed cases. B. pertussis DNA was identified in 81.8 % of cases and B. parapertussis DNA in 18.2 % of cases., Conclusion: The study exposes a significant pertussis outbreak affecting predominantly young infants., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Inc.)

Published
2024
Full Text
View/download PDF

48. Dataset of acute respiratory infections: Epidemiological and etiological data from a cohort of 801 Moroccan children.

Author

Tligui H, Hattoufi K, Jroundi I, Mahraoui C, and Bassat Q

Abstract

Acute respiratory infections remain a leading cause of death among young children in low- and middle-income countries. The etiological diagnosis of these infections is challenging due to the similarity in clinical presentations and overlapping symptoms caused by various pathogens. This database provides comprehensive epidemiological, clinical, paraclinical, and biological data on 801 Moroccan children admitted to the Children's Hospital of Rabat for the management of Clinical Severe Pneumonia. Identification of the pathogens responsible of respiratory infections was carried out using blood samples for hemoculture, standard bacterial culture and multiplex RT-PCR using the TrueScience RespiFinder Pathogen Identification Panel (Applied Biosystems)., (© 2024 The Authors.)

Published
2024
Full Text
View/download PDF

49. Multifocal tuberculosis in children: A case of spinal tuberculosis.

Author

Aouraghe H, Benchekroun S, Mahraoui C, and ElHafidi N

Subjects
Adult, Female, Child, Humans, Antitubercular Agents therapeutic use, Lymph Nodes, Skin, Tuberculosis, Spinal diagnostic imaging, Tuberculosis, Spinal drug therapy, Discitis drug therapy, Mycobacterium tuberculosis genetics
Abstract

Multifocal tuberculosis (TB) accounts for up to one-third of all cases of TB and children are at higher risk for extrapulmonary TB than adults. Spinal TB is the regular form of skeletal TB. Spondylodiscitis TB represents 47%-94% of spinal TB. Cervical localization is rare but remains dangerous because of diagnostic difficulties and severe complications. We report a case of a 10-year-old Moroccan girl, bacille Calmette-Guerin vaccinated, with no medical history or trauma, parents and siblings are healthy and no contact with TB. The patient was complaining of neck pain, asthenia, and loss of weight for 1 year. During this period, she had been treated with analgesics and anti-inflammatory drugs, with no clinical evolution. The parents consulted the pediatric emergency room when they noticed a tumefaction in the middle thoracic region. Physical examination found a pectus carinatum deformity, palpable axillary, and submandibular lymph node, and a fixed palpable median thoracic mass fistulized to the skin. The GeneXpert MTB/RIF and QuantiFERON-TB Gold assay were positive. Chest computed tomography showed cervicodorsal spondylodiscitis staged at C5-D10, with abscessed perivertebral and peristernal collections, with epidural extension at C5-C6 and pleural level. The presence of an axillary lymph node with necrotic center. The skin biopsy showed a morphological appearance of epithelial and gigantocellular granulomatous inflammation. The patient had pharmacological treatment anti-TB drug with fixed-dose combination regimen and supportive therapy for pain management., Competing Interests: None

Published
2023
Full Text
View/download PDF

50. Genetic Diagnosis of Inborn Errors of Immunity in an Emerging Country: a Retrospective Study of 216 Moroccan Patients.

Author

Moundir A, Ouair H, Benhsaien I, Jeddane L, Rada N, Amenzoui N, Jouhadi Z, Adnane F, Hafidi NE, Kili A, Bourhanbour Drissi A, Babakhouya A, Benmiloud S, Hbibi M, Benajiba N, Hida M, Bouskraoui M, Mahraoui C, Admou B, Bakkouri JE, Ailal F, and Bousfiha AA

Subjects
Humans, Retrospective Studies, Mutation genetics, Hereditary Complement Deficiency Diseases, Morocco epidemiology, Genetic Testing
Abstract

Purpose: Genetic testing provides great support to validate the clinical diagnosis of inborn errors of immunity (IEI). However, the high cost and advanced technology make these tests inaccessible to a large proportion of patients in low-income countries. In the present study, we aim to evaluate the Moroccan experience in genetic testing and to report the main molecular features and difficulties encountered in genetic diagnosis., Methods: We performed a multi-center retrospective analysis of all patients with a molecular diagnosis and registered in the national registry between 2010 and 2022. To estimate the impact of the newly identified mutations, we calculated the Combined Annotation Dependent Depletion (CADD) score and the mutation significance cutoff (MSC) for each variant., Results: A total of 216 (29%) patients received a genetic diagnosis out of 742 patients with IEI included in the registry. All genetic tests were performed in the context of thesis projects (40%) or international collaborations (60%). A set of 55 genetic defects were identified, including 7 newly reported: SNORA31, TBX21, SPPL2A, TYK2, RLTPR, ZNF341, and STAT2 GOF. Genetic diagnoses were more frequent in the defects of innate and intrinsic immunity with a percentage of 78%, while antibody deficiencies had a lower frequency with a percentage of 17.5%. Only one genetic diagnosis has been made in the complement deficiency group. The most commonly used molecular techniques were Sanger sequencing (37%) followed by targeted gene sequencing (31%)., Conclusion: The thesis projects and collaborations were beneficial as they allowed us to provide a definitive genetic diagnosis to 29% of the patients and to contribute to the identification of new genetic defects and mutations. These results offer insight into the progress made in genetic diagnoses of IEI in Morocco, which would provide a baseline for improving the clinical management of patients with IEI., (© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results