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Relationships between physiological parameters and 5-km running performance were examined in 15 male runners (17.3 +/- 0.9 years). Running economy (RE) and blood lactate concentration ([BLa]) at 241.2 m/min, VO2max, velocity at VO2max (vVO2max), vertical jump height and muscle power, and isokinetic knee extension strength at 60degrees/sec and 240degrees/sec were measured. The participants' best 5-km race time over the last month of the cross-country season (16.98 +/- 0.76 min) was used in the analysis. The data were analyzed using Pearson correlation coefficients. Significant relationships to run time were observed for VO2max (r = -.53), RE (r = .55), and vVO2max (r = -.66), but not [BLa], isokinetic muscle torque, or vertical jump. Identifying the unique strength and power characteristics related to running performance in this age group is warranted. [ABSTRACT FROM AUTHOR]

This study examined overall, leg, and chest ratings of perceived exertion (RPE) in 16 children (10.7 +/- 0.8 yr) and 16 adults (24.2 +/- 1.8 yr) during 16 min of exercise performed at an intensity equal to ventilatory threshold (-64% of VO2max for the children and 61% of VO2max for the adults). Physiological and perceptual responses were measured at 8 and 16 min. RPE in the children ranged from 11.6 +/- 2.3 (chest) to 12.6 +/- 2.6 (leg) at 8 min, and from 13.3 t 2.8 (chest) to 15.1 +/- 2.9 (leg) at 16 min. In adults, RPE ranged from 10.9 +/- 1.9 (chest) to 12.0 +/- 1.8 (leg) at 8 min, and from 11.8 +/- 2.1 (chest) to 13.3 +/- 1.6 (leg) at 16 min. Between groups, RPE tended to be higher and increased more over time in the children compared to the adults (P < .08). RPE at 8 min was less than RPE at 16 min, and overall and leg RPE were greater than chest RPE. Children were able to discriminate sensory information arising from different physiological variables; however, the specific physiological cues underlying the perception of effort remains uncertain in this age group. [ABSTRACT FROM AUTHOR]

This study examined the occurrence of a VO2 plateau at maximal exercise, and whether ventilatory threshold (VT) differed between children who do and children who do not achieve a VO2 plateau at maximal exercise. After performing a graded exercise test on a treadmill to assess VT and VO2max, the children were divided into a plateau group (n = 14) and a nonplateau group (n = 12). There were no differences with respect to the VO2 at VT (36.7 + or - 3.4 vs. 37.9 + or - 5.4 ml x kg[-1] x min[-1] and VO2max (51.6 + or - 5.4 vs. 54.6 + or - 3.6 ml x kg[-1] x min[-1]) in the plateau and nonplateau groups, respectively. The mean HR, RER, and RPE at maximal exercise were also similar between groups. These results indicate that VT and VO2max are similar in children regardless of the occurrence of a VO2 plateau at maximal exercise. Furthermore, a plateau in VO2 during a maximal exercise test is not mandatory for assessment of VO2max in this age group. [ABSTRACT FROM AUTHOR]

PURPOSE: To examine the changes in heart rate (HR) after two different submaximal exercise bouts in boys and girls. METHODS: Eleven boys (10.5 +/- 1.0 yr) and 10 girls (10.8 +/- 0.7 yr) participated in this study. Each child completed an initial graded exercise test to determine peak VO2. On subsequent and separate days, a 5-min submaximal exercise bout on a cycle ergometer was performed. One bout was conducted at 70 W, and the other bout corresponded to an intensity of 85-90% of peak VO2. VO2 and HR were measured during and after (1 min and 3 min). HR recovery responses from each submaximal exercise bout were analyzed using a group by time ANOVA, and Pearson-product correlations were determined between resting HR, peak VO2, and postexercise HR responses. RESULTS: HR in the boys was lower at the end of exercise and the first minute of recovery versus girls but not at the 3rd min of recovery. There were no differences in HR recovery after the relative exercise bout. Resting HR was significantly correlated with postexercise HR from both bouts (r = 0.52-0.69), whereas peak VO2 did not correlate to postexercise HR. ANCOVA using resting HR as the covariate eliminated the gender different noted with the recovery from the 70-W bout. CONCLUSIONS: In summary, postexercise HR responses differed between boys and girls when submaximal exercise was performed at an absolute work rate. When exercise was performed at a relative intensity, HR recovery responses were similar between the two groups. Resting HR appears to account for variations in postexercise HR better than peak VO2. [ABSTRACT FROM AUTHOR]

The purpose of this study was to examine the rating of perceived exertion (RPE) at maximal exercise in children performing three different graded exercise tests on a treadmill. Eighteen children with a mean +/-SD age of 10.3 +/- 1.4 years volunteered for this study. Each subject performed three different graded exercise test protocols on a treadmill. The protocols consisted of walking only, running only, and combination walk/run. Mean VO2max (ml.kg-l.min-l) during the walking trial (47.3 +/- 5.0) was significantly (p<0.05) less than during the running (52.1 +/- 4.9) and combination trials (51.9 +/- 5.1). Mean HRmax (bpm) was significantly (p<0.05) lower during the walking test (195.2 +/- 7.9) compared to the running (202.2 +/- 7.4) and combination tests (202.3 +/- 6.6). Mean RPE at maximal exercise was 18.1 +/- 2.1 in the walking trial, 16.8 +/- 3.0 in the running trial, and 16.8 +/- 2.6 in the combination trial, and was significantly (p<0.05) greater in the walking trial compared to the othe two testing protocols. These data indicate that although VO2max during a walking test is lower, effort sensation is higher compared to protocols that use running as the mode of exercise. The factors involved with RPE selection in this age-group remain to be established. [ABSTRACT FROM AUTHOR]

Background: Oxygen uptake efficiency slope (OUES) is an objective physiological measure that can be obtained from a standard graded exercise test. However, there is conflicting evidence regarding sex differences in OUES values in children. Therefore, this study investigated potential sex differences in absolute, ratio-scaled, and allometrically scaled OUES in 8.0- to 12.0-year-old children., Methods: Retrospective and prospective data of 18 boys and 22 girls were utilized. All participants had undergone familiarization before performing a maximal cycle ergometer test to determine OUES. These values were also ratio-scaled and allometrically scaled to mass and body surface area (BSA). Group differences were tested via independent sample t-tests (or Mann-Whitney U if not normally distributed)., Results: Absolute OUES values (VO2 mL∙min -1 /log10VE L∙min -1 ) were significantly higher in boys compared to girls (1860.8±359.3 vs. 1514.3±212.6). When scaled to mass (VO2 mL∙kg -1 ∙min -1 /log10VE L∙kg -1 ∙min -1 ), OUES was no longer significantly different between groups, but when scaled to BSA (VO2 mL∙m -2 ∙min -1 /log10VE L∙m -2 ∙min -1 ), OUES was significantly higher in the boys than the girls (1414.4±204.2 vs. 1268.9±134.6). When allometry was applied for mass (OUES/mass 0.444 ) boys had significantly higher value than girls (350.8±46.7 vs. 305.0±31.5)., Conclusions: The present study demonstrated that boys had greater OUES values scaled to BSA and allometrically scaled to body mass. These findings provide further evidence of sex differences with OUES values in preadolescent children and implies the need for sex-specific reference values prior to using OUES for the assessment of cardiorespiratory pathology in children.

Purpose of Review: Examine the current state of literature related to the impact of obesity in children and adolescents on health-related physical fitness and the resultant cardiometabolic disease risk., Recent Findings: Cardiorespiratory fitness of children and adolescents has declined over the past few decades which corresponds with an increase in obesity rates. Children with obesity are more likely to have low cardiorespiratory fitness which is associated with higher cardiometabolic disease risk and poorer mental health. The impact of obesity on muscular fitness in children and adolescents is more difficult to ascertain, but in general measures of physical function are lower in children with obesity which has also been associated with higher cardiometabolic disease risk. Components of health-related physical fitness are trending negatively in children and adolescents and appear to be related to the increase in prevalence of obesity. The resultant cardiometabolic disease risk has also risen which suggests a greater disease burden in the future. These disparaging findings highlight the need for aggressive interventions to improve physical fitness in children and adolescents., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Purpose: This study examined metabolic flexibility with respect to fat metabolism during exercise in children who are lean (n=11; 10.9[0.9] y) and overweight/obese (OW/OB; n=9; 10.3[1.2] y)., Method: Participants were grouped based on body mass index percentiles for age and sex. Groups were mixed in age and sex. Participants completed two 20-minute exercise bouts on a cycle ergometer, separated by a 10-minute rest. Bout 1 consisted of 10 minutes at 50% VO2peak and 10 minutes at 75% VO2peak. Bout 2 was 20 minutes at 50% VO2peak. Absolute fat oxidation rate (FOR), FOR relative to body mass, FOR relative to fat-free mass, and proportional fat use were measured at 10 minutes of bout 1 and 5, 10, 15, and 20 minutes of bout 2., Results: Absolute FOR was higher in the OW/OB group (range: 117.8 [55.1]-206.2 [48.3] mg·min-1) than in the lean group (81.1 [32.2]-152.2 [38.2] mg·min-1); however, there were no significant main effects for group or significant interactions for proportional fat use, FOR relative to body mass, or FOR relative to fat-free mass., Conclusion: Children in this age range who are overweight/obese do not display impaired metabolic flexibility with respect to fat metabolism during exercise.

Objectives: This study examined the effect of maturation on parasympathetic nervous system (PNS) response from rest to light- to moderate-intensity exercise and recovery from maximal exercise in pre- ( n  = 10; maturity offset = -3.0 ± 1.2 years; age = 10.1 ± 1.9 years), mid- ( n  = 9; maturity offset = -0.1 ± 0.6 years; age = 13.7 ± 1.0 years), and postpubertal ( n  = 10; maturity offset = 1.9 ± 0.6 years; age = 15.6 ± 1.2 years) boys and men ( n  = 10; age = 24.1 ± 2.0 years)., Design: Participants completed seated rest, light-intensity exercise (50% HR max ), and moderate-intensity exercise (65% HR max ). Following moderate-intensity exercise, intensity was ramped to elicit maximal HR and followed by 25 min of seated recovery. Log transformed values for root mean square of successive differences (lnRMSSD), high-frequency power (lnHF) and normalized HF power (lnHFnu) assessed PNS modulation during 3 min of rest, light-intensity exercise, moderate-intensity exercise, and 3-min epochs throughout recovery., Results: During light-intensity exercise, lnRMSSD and lnHF were greater in prepubertal (lnRMSSD = 3.4 ± 0.3 ms; lnHF = 5.4 ± 0.7 ms 2 ) compared to men (lnRMSSD = 2.8 ± 0.5 ms; lnHF = 4.0 ± 0.9 ms 2 ). During moderate-intensity exercise, lnHF differed between prepubertal and men (2.8 ± 1.0 vs. 1.4 ± 1.0 ms 2 ). During recovery, HRV variables were greater in prepubertal compared to postpubertal and men., Conclusions: Prepubertal boys have reduced PNS withdrawal during light-intensity exercise and greater PNS reactivation following exercise.

Purpose: This study examined the physiological, perceptual, and performance effects of a 6% carbohydrate (CHO) drink during variable-intensity exercise (VIE) and a postexercise test in premenarchal girls., Methods: A total of 10 girls (10.4 [0.7] y) participated in the study. VO2peak was assessed, and the girls were familiarized with VIE and performance during the first visit. The trial order (CHO and placebo) was randomly assigned for subsequent visits. The drinks were given before VIE bouts and 1-minute performance (9 mL/kg total). Two 15-minute bouts of VIE were completed (10 repeated sequences of 20%, 55%, and 95% power at VO2peak and maximal sprints) before a 1-minute performance sprint., Results: The mean power, peak power, heart rate (HR), %HRpeak, and rating of perceived exertion during VIE did not differ between trials. However, the peak power decreased, and the rating of perceived exertion increased from the first to the second bout. During the 1-minute performance, there were no differences between the trial (CHO vs placebo) for HR (190 [9] vs 189 [9] bpm), %HRpeak (97.0% [3.2%] vs 96.6% [3.0%]), rating of perceived exertion (7.8 [2.3] vs 8.1 [1.9]), peak power (238 [70] vs 235 [60] W), fatigue index (54.7% [10.0%] vs 55.9% [12.8%]), or total work (9.4 [2.6] vs 9.4 [2.1] kJ)., Conclusion: CHO supplementation did not alter physiological, perceptual, or performance responses during 30 minutes of VIE or postexercise sprint performance in premenarchal girls.

Purpose: The effect of carbohydrate (CHO) supplementation on physiological and perceptual responses to steady-state exercise has been studied in children. However, little is known about these responses to variable-intensity exercise (VIE) and how these responses might differ from adults. This study examined the physiological and perceptual effects of CHO on VIE in boys and men., Methods: Eight boys (11.1 ± 0.9 years) and 11 men (23.8 ± 2.1 years) consumed CHO or a placebo (PL) beverage before and throughout VIE (three 12-min cycling bouts with intensity varying every 20-30 s between 25, 50, 75, and 125% peak work rate). Pulmonary gas exchange was assessed during the second 12-min bout. RPE was assessed twice per bout., Results: In CHO, blood glucose increased and then decreased more from pre-exercise to 12 min and was higher in this trial at the end of exercise in men versus boys. In boys, blood glucose in CHO was higher at 24 and 36 min of exercise than in PL. RER during the CHO trial was higher in both groups; the other physiological responses were unaffected by CHO. All RPE measures (whole body, legs and chest) increased over time, but were not different between groups or trials., Conclusion: Blood glucose patterns during VIE were differentially affected by CHO in boys and men, but most physiological and perceptual responses to VIE were unaffected by CHO in either group. Knowledge of the underlying mechanisms of glucose regulation and effects on physical performance during this type of exercise in children is warranted.

OMNI ratings of perceived exertion (RPE) and physiological responses in children (n=7 boys, 8 girls, 11.1±1.0 years) were examined during estimation (graded exercise test [GXT] and steady-state) and production (steady-state) trials on a cycle ergometer. Peak oxygen consumption (VO 2 peak) was determined via a GXT with RPE estimated every 30 s. Later, two 6-min trials were completed: Participants 1) estimated RPE at ~75% of VO 2 peak, 2) produced a level of exertion corresponding to their RPE at ~75% of VO 2 peak during the GXT. Data analysis included a one-way MANOVA and a paired t-test. The target intensity during the GXT corresponded to 74.2±2.5% of VO 2 peak; the steady-state estimation and production trials were performed at 76.5±2.7% and 68.5±14.1% of VO 2 peak, respectively (p>0.05). Mean RPE at ~75% of VO 2 peak during the GXT and production trial was 6.7±1.5; during the steady-state estimation trial RPE was 5.8±2.0 (p>0.05). There were no differences (p>0.05) in the physiological responses. Participants estimated RPE similarly at ~75% of VO 2 peak during both graded and steady-state exercise, but when asked to produce a given RPE, marked variability was observed in physiological responses. These findings may have implications in optimizing exercise prescriptions for children., Competing Interests: Conflict of Interest: The authors have no conflict of interest to declare., (© Georg Thieme Verlag KG Stuttgart · New York.)

Purpose: This study examined heart rate recovery (HRR) and heart rate variability (HRV) following maximal exercise in lean (<85th percentile age- and sex-BMI percentile; n = 11 (♂=5; ♀=6); 10.1 ± 0.7 years) and overweight (≥85th age- and sex-BMI percentile; n = 11 (♂=5; ♀=6); 10.5 ± 1.2 years) children., Method: Participants completed a 10-min rest, followed by a graded exercise test to maximal effort. HRV, in the time and frequency domains, was assessed during rest and recovery. Also during recovery, one-minute HRR and the time constant of a monoexponential line of best fit (HRRt) were determined., Results: There were no significant differences in one-minute HRR and HRRt between the lean (56 ± 7 beats∙min -1 and 160.4 ± 80.1 s, respectively) and overweight (51 ± 16 beats∙min -1 and 141.1 ± 58.1 s, respectively) groups. There also were no significant interactions between groups from rest to recovery for any HRV variables. Root mean square of successive differences (RMSSD) and high frequency power (HF) during recovery was 2.05 ± 0.49 ms and 3.30 ± 1.02 ms 2 in the lean children, respectively. In the overweight children, RMSSD and HF were 1.88 ± 0.65 ms and 2.94 ± 1.27 ms 2 , respectively., Conclusion: HRR and HRV findings suggest there are no differences in autonomic function during recovery from maximal exercise in lean and obese 8- to 12-year old children.

Purpose: This study examined heart rate recovery (HRR) and heart rate variability (HRV) following submaximal and maximal exercise in boys (n = 13; 10.1 ± 0.8 years) and girls (n = 12; 10.1 ± 0.7 years)., Methods: Participants completed 10 min of supine rest followed by a graded exercise test to maximal effort. On a separate day, participants performed submaximal exercise at ventilatory threshold. Immediately following both exercise bouts, 1-min HRR was assessed in the supine position. HRV variables were analyzed under controlled breathing in the time and frequency domains over the final 5 min of rest and recovery., Results: There were no significant differences in HRR following maximal and submaximal exercise between boys (58 ± 8 and 59 ± 8 beats min(-1), respectively) and girls (54 ± 6 and 52 ± 19 beats min(-1), respectively). There also were no significant interactions between groups from rest to recovery from maximal exercise for any HRV variables. However, there was a difference in the response between sexes from rest to recovery from submaximal exercise for log transformed standard deviation of NN intervals (lnSDNN) and log transformed total power (lnTP). No differences were observed for lnSDNN at rest (boys = 4.61 ± 0.28 vs. girls = 4.28 ± 0.52 ms) or during recovery (lnSDNN: boys 3.78 ± 0.46 vs. girls 3.87 ± 0.64 ms and lnTP: boys 7.33 ± 1.09 vs. girls; 7.44 ± 1.24 ms(2)). Post hoc pairwise comparisons showed a significant difference between boys and girls for lnTP at rest (boys = 9.14 ± 0.42 vs. girls = 8.30 ± 1.05 ms(2))., Conclusion: Parasympathetic modulation was similar between boys and girls at rest and during recovery from exercise, which could explain similarities observed in HRR.

The purpose of this study was to examine the influence of postexercise parasympathetic modulation, measured by heart rate variability (HRV), on heart rate recovery (HRR) in boys (n = 13, 10.1 ± 0.8 years) and men (n = 13, 23.9 ± 1.5 years) following maximal and submaximal exercise. Subjects completed 10 min of supine rest, followed by graded exercise on a cycle ergometer to maximal effort. On a separate day, subjects exercised at an intensity equivalent to ventilatory threshold. Immediately following both exercise bouts, 1-min HRR was assessed in the supine position. HRV was analyzed under controlled breathing during the final 5 min of rest and recovery in the time and frequency domains and transformed to natural log (ln) values. Boys had a greater 1-min HRR than men following maximal (58 ± 8 vs. 47 ± 11 beats·min(-1)) and submaximal (59 ± 8 vs. 47 ± 15 beats·min(-1)) exercise (p < 0.05). Following maximal exercise, boys had greater ln root mean square successive differences in R-R intervals (2.52 ± 0.95 ms), ln standard deviation of NN intervals (3.34 ± 0.57 ms), ln high-frequency power (4.32 ± 2.00 ms(2)), and ln low-frequency power (4.98 ± 1.17 ms(2)) than men (1.33 ± 0.37 ms, 2.52 ± 0.24 ms, 1.32 ± 1.06 ms(2) and 2.80 ± 0.74 ms(2), respectively) (p < 0.05). There were no differences in any HRV variables between groups following submaximal exercise (p > 0.05). In conclusion, it appears that greater parasympathetic modulation accounts for greater HRR following maximal exercise in boys versus men. Although submaximal HRR was greater in boys, parasympathetic responses were similar between groups.

Exercise metabolism in children has traditionally been assessed using the respiratory exchange ratio (RER) to determine the contributions of fat and carbohydrate to the exercise energy demands. Although easily measured, RER measurements have limitations. Other methods to assess metabolism such as the obtainment of a muscle biopsy and the use of nuclear magnetic resonance spectroscopy carry ethical and feasibility concerns, respectively, which limit their use in studies involving children. Stable isotopes, used routinely in studies involving adults, can also be applied in studies involving children in an ethical and feasible manner. Two common stable isotopes used in metabolic studies involving children include carbon-13 (¹³C) and nitrogen-15 (¹⁵N). ¹³C-glucose can be used to study carbohydrate metabolism and ¹⁵N-glycine can be used to assess protein metabolism. This article reviews the use of ¹³C-glucose and ¹⁵N-glycine to study exercise metabolism in children, considers some of the associated ethical aspects, explains the general methodology involved in administering these isotopes and the resources required, and describes studies involving children utilizing these methods. Finally, suggestions for future research are provided to encourage further use of these techniques.

Exercise metabolism in children has traditionally been assessed using the respiratory exchange ratio (RER) to determine the contributions of fat and carbohydrate to the exercise energy demands. Although easily measured, RER measurements have limitations. Other methods to assess metabolism such as the obtainment of a muscle biopsy and the use of nuclear magnetic resonance spectroscopy carry ethical and feasibility concerns, respectively, which limit their use in studies involving children. Stable isotopes, used routinely in studies involving adults, can also be applied in studies involving children in an ethical and feasible manner. Two common stable isotopes used in metabolic studies involving children include carbon-13 (C) and nitrogen-15 (N). C-glucose can be used to study carbohydrate metabolism and N-glycine can be used to assess protein metabolism. This article reviews the use of C-glucose and N-glycine to study exercise metabolism in children, considers some of the associated ethical aspects, explains the general methodology involved in administering these isotopes and the resources required, and describes studies involving children utilizing these methods. Finally, suggestions for future research are provided to encourage further use of these techniques.

This study examined the influence of maturation on the oxygen uptake efficiency slope (OUES) in healthy male subjects. Seventy-six healthy male subjects (8-27 yr) were divided into groups based on maturation status: prepubertal (PP), midpubertal (MP), late-pubertal (LP), and young-adult (YA) males. Puberty status was determined by physical examination. Subjects performed a graded exercise test on a cycle ergometer to determine OUES. Group differences were assessed using a one-way ANOVA. OUES values (VO(2)L·min(-1)/log(10)V(E)L·min(-1)) were lower in PP and MP compared with LP and YA (p < .05). When OUES was expressed relative to body mass (VO(2)mL·kg-1·min(-1)/log(10)V(E)mL·kg(-1)·min(-1)) differences between groups reversed whereby PP and MP had higher mass relative OUES values compared with LP and YA (p < .05). Adjusting OUES by measures of body mass failed to eliminate differences across maturational groups. This suggests that qualitative factors, perhaps related to oxidative metabolism, account for the responses observed in this study.

The effect of stimulant medication use by children with attention deficit/hyperactivity disorder (ADHD) on the rating of perceived exertion (RPE)-heart rate (HR) relationship was examined. Children with ADHD (n=20; 11.3±1.8 yrs) and children without ADHD (n=25; 11.2±2.1 yrs) were studied. Children with ADHD were examined while on their usual dose of medication on the day of study. HR and RPE, using the OMNI RPE scale, were assessed during a graded exercise to peak voluntary effort. The RPE-HR relationship was determined individually and the intercept and slope responses were compared between groups. The intercept was 132.4±19.5 bpm for children with ADHD and 120.6±15.7 bpm for children without ADHD. The slope was 7.3±1.9 bpm/RPE for the children with ADHD and 8.1±1.6 bpm/ RPE for the children without ADHD. For the group with ADHD the intercept and slope values fell outside of the 95% CI observed in the control group. The altered relationship between RPE and HR with stimulant medication use in children with ADHD has practical implications with respect to the use of HR and RPE to monitor exercise intensity.

Carbohydrate (CHO) consumption before anaerobic exercise was studied in 13 adolescent boys (15.2 ± 0.9 yrs). A within subjects design was employed where subjects consumed a 22% CHO or volume-matched placebo (PL) beverage 30-min before anaerobic exercise on two separate days. Exercise consisted of a Wingate Anaerobic Test (WAnT), ten by 10-s-sprints, and a second WAnT. Fatigue index and peak power (PP) were similar while mean power (MP) was higher (p < .025) in CHO trial; however this difference was ascribed to initial WAnT performance. PP and MP for the 10-s sprints were similar between trials. Intravenous blood glucose and insulin concentrations were higher (p < .05) in the CHO trial while lactate and catecholamine concentrations were similar. Improved performance on a single WAnT was apparent with CHO consumption before exercise; however, this strategy did not attenuate fatigue over time in adolescent boys.

The relationship between ventilatory (VT) and lactate threshold (LT) in 8 boys (11.1 +/- 0.7 yrs) and 9 men (24.0 +/- 3.3 yrs) with similar peak VO(2) levels was assessed. Percent peak VO(2) at VT and LT were higher (P < 0.05) in the boys (67.9 +/- 2.6% and 63.9 +/- 5.0%, respectively) compared with men (59.0 +/- 3.2% and 54.8 +/- 2.7%, respectively). VO(2) (mL.kg(-1).min(-1)) at VT was higher (P < 0.05) and at LT tended to be higher in boys. Correlations between VT and LT were r = 0.95 for VO(2) (mL.kg(-1).min(-1)) and r = 0.82 for % peak VO(2) (P < 0.05) in boys and r = 0.87 (P < 0.05) and r = 0.60 (P > 0.05), respectively, in men. The mechanisms mediating VT and LT in children are not established fully and warrant further study.

This study examined the effect of preexercise carbohydrate (CHO) feeding on performance on a Wingate anaerobic test (WAnT) in 11 boys (10.2 +/- 1.3 y old). Four WAnTs with 2 min recovery were performed 30 min after consuming a CHO (1 g CHO/kg) or placebo drink. Peak power (PP) and mean power (MP) were similar between trials. PP ranged from 241.1 +/- 82.2 to 223.1 +/- 57.9 W with carbohydrate and from 238.2 +/- 76.1 to 223.4 +/- 52.3 W with placebo. MP ranged from 176.3 +/- 58.4 to 151.1 +/- 37.5 W with carbohydrate versus 178.0 +/- 45.8 to 159.1 +/- 32.7 W with placebo. Preexercise glucose was significantly higher in CHO versus placebo (7.0 +/- 1.0 vs. 5.5 +/- 0.5 mmol/L), but postexercise values were not different. Blood lactate was similar between trials but increased over time. This study found that the ingestion of a CHO solution before exercise did not influence power output during repeated performances of the WAnT.

This study examined substrate use during exercise in early-pubertal (EP), mid-pubertal (MP), late-pubertal (LP), and young-adult (YA) males. Fuel use was calculated using the RER and VO2 response during cycling exercise at 30 to 70% of VO2speak. Significant group by intensity interactions were found for lactate, RER, percent CHO, and fat use, in addition to fat and CHO oxidation rates, which suggest a maturation effect on substrate use during exercise. While significance was not achieved at all intensities, post hoc analyses revealed greater fat use, lower CHO use, and lower lactate concentrations in EP and MP compared to LP or YA. No differences were noted between EP and MP or LP and YA at any intensity, suggesting the development of an adult-like metabolic profile occurs between mid- to late-puberty and is complete by the end of puberty.

Because little is known about the effects of aging on perceived exertion, the aim of this article is to review the key findings from the published literature concerning rating of perceived exertion (RPE) in relation to the developmental level of a subject. The use of RPE in the exercise setting has included both an estimation paradigm, which is the quantification of the effort sense at a given level of exercise, and a production paradigm, which involves producing a given physiological effort based on an RPE value. The results of the review show that the cognitive developmental level of children aged 0-3 years does not allow them to rate their perceived exertion during a handgrip task. From 4 to 7 years of age, there is a critical period where children are able to progressively rate at first their peripheral sensory cues during handgrip tests, and then their cardiorespiratory cues during outdoor running in an accurate manner. Between 8 and 12 years of age, children are able to estimate and produce 2-4 cycling intensities guided by their effort sense and distinguish sensory cues from different parts of their body. However, most of the studies report that the exercise mode and the rating scale used could influence their perceptual responsiveness. During adolescence, it seems that the RPE-heart rate (HR) relationship is less pronounced than in adults. Similar to observations made in younger children, RPE values are influenced by the exercise mode, test protocol and rating scale. Limited research has examined the ability of adolescents to produce a given exercise intensity based on perceived exertion. Little else is known about RPE in this age group. In healthy middle-aged and elderly individuals, age-related differences in perceptual responsiveness may not be present as long as variations in cardiorespiratory fitness are taken into account. For this reason, RPE could be associated with HR as a useful tool for monitoring and prescribing exercise. In physically deconditioned elderly persons, a rehabilitation training programme may increase the subject's ability to detect muscular sensations and the ability to utilise these sensory cues in the perception of effort. RPE appears to be a cognitive function that involves a long and progressive developmental process from 4 years of age to adulthood. In healthy middle-aged and elderly individuals, RPE is not impaired by aging and can be associated with HR as a useful tool to control exercise intensity. While much is known about RPE responses in 8- to 12-year-old children, more research is needed to fully understand the influence of cognitive development on perceived exertion in children, adolescents and elderly individuals.

Adaptations in aerobic exercise responses as well as the relationship between aerobic exercise responses and running performance were examined in a group of previously trained adolescent runners (n = 9; 15.9 +/- 1.0 years) over the course of a competitive cross-country season. Running economy (RE), submaximal blood lactate concentration [BLa] and VO2max were assessed before and immediately after the season. Five-km race time improved (P < 0.05) from 18.68 +/- 1.10 min at the beginning of the season to 18.16 +/- 1.11 min at the end of the season. Significant increases were observed in peak VO2 (61.6 +/- 3.5 to 65.3 +/- 2.9 mL x kg(-1) x min(-1)) and graded exercise test time (11.32 +/- 1.56 to 12.22 +/- 0.79 min). There was a tendency for RE (P = 0.051) to worsen slightly and for [BLa] (P = 0. 057) to decline as a result of training. At the beginning of the season submaximal [BLa] at 14 km x hr(-1) (r = 0.86) and graded exercise test time (r = -0.87) were significantly related to 5-km time. At the end of the season, RE (r = 0.78) and [BLa] (r = 0.77) at 14 km x hr(-1) and graded exercise test time (r = -0.69) were significantly related to race time. In this well-trained group of runners, further training during the cross-country season increased peak VO2 and improved race time. Submaximal [BLa] and graded exercise test time appear to be the most robust predictors of performance, while RE became a significant predictor of race time at the end of the season.

Aim: This study examined the relationship of 3-km run time to indices of aerobic and anaerobic ability in 9 male runners (13.4+/-0.6 years, mean+/-SD)., Methods: Anthropometric measurements were made, and an exercise test to determine running economy at 187 m x min(-1) and (.-)VO(2max) were assessed on a treadmill. On a separate day, 2 55-m sprints followed by a 3-km run were performed on a 200-m indoor track. Capillary blood samples were obtained from a finger tip immediately after the run to determine blood lactate level. Fractional utilization (%(.-)VO(2max) used during the 3-km run) was calculated. Correlations were used to examine the relationship between run time and the physiological measurements., Results: Mean values for (.-)VO(2), HR and RER at maximal exercise were 61.7+/-4.4 ml x kg(-1)xmin(-1), 198.9+/-6.7 b x min(-1), and 1.16+/-0.04, respectively. The average time to run 3 km was 13.27+/-0.97 min (90.1+/-7.2% of (.-)VO(2max)). Post-run blood lactate level was 8.3+/-3.2 mmol x L(-1) and was significantly related (r=-0.73, p=0.02) to 3-km time. Fractional utilization tended to be related (r=-0.56, p=0.12) to time., Conclusions: In this age group the ability to run at a high percentage of (.-)VO(2max) and tolerate a high blood lactate appear to be important determinants of running performance in young male runners.

This study examined ratings of perceived exertion (RPE) using Borg's 6-20 scale at 50 W, 80 W, and ventilatory threshold (VT) in 10-year-old children (n = 15) during two different graded exercise tests. Power output was increased by 10 W.min(-1) in one protocol and by 30 W.3 min(-1) in the other. The cardiorespiratory responses at VT and peak exercise were similar between protocols. At 50 W and 80 W the cardiorespiratory responses were generally lower (P < 0.05) in the 10W trial. However, RPE was 11.5 +/- 2.9 and 12.1 +/- 3.2 at 50 W and 15.1 +/- 2.7 and 15.3 +/- 2.8 at 80 W in the 10-W and 30-W trials, respectively (P > 0.05). The RPE at VT was 13.9 +/- 2.4 in the 10-W trial and 12.4 +/- 2.4 in the 30-W trial (P < 0.05). In that variations in submaximal RPE did not coincide with variations in central mediators of exertion, locals cues of exertion may have provided the dominate sensory signal.

Background: This study tested the hypothesis that the occurrence of a VO(2) plateau at maximal exercise would be greater in men versus boys. Secondary indicators of maximal effort also were examined., Methods: Sixteen boys (10.7+/-0.6 yrs) and 21 men (22.5+/-2.0 yrs) performed a graded exercise test on a treadmill at a constant speed of 8.04 km x hr(-1) with 2.5% increments in elevation. The men also performed a second test at 11.26 km x hr(-1) with similar increases in slope., Results: At 8.04 km x hr(-1) , VO(2) max was 52.3+/-6.0 and 52.5+/-5.1 ml x kg(-1) x min(-1) in boys and men, respectively (p>0.05). In the men, VO(2) max (53.3+/-5.4 ml x kg(-1) x min(-1) ) was higher (p<0.05) in the faster protocol. The percentage of men achieving the criterion was nearly double the percentage of boys (23.8 vs 12.5%), although the difference was not significant. Age-specific criteria heart rate (HR) and respiratory exchange ratio (RER) were achieved in a similar manner; however, more men (100%) than boys (86.7%) achieved an age-specific blood lactate (BLa) criterion (p<0.05). Plateau achievement increased to 33.0% in the 11.26 km x hr(-1) protocol, but was not significantly different from 8.04 km x hr(-1). HR, RER and BLa criteria achievement were comparable., Conclusions: Maturation may influence the achievement of a plateau and BLa criteria, but not age-specific criteria for RER or HR.

The purpose of this study was to examine overall, leg and chest ratings of perceived exertion (RPE) at ventilatory threshold (Thvent) in 16 children (mean age 10.9 years) and 17 adults (mean age 24.3 years). Thvent and maximum oxygen consumption (VO2max) were measured during a graded exercise test on a cycle ergometer. Overall, leg and chest RPE were obtained at the end of each exercise stage. VO2max was 49.9 (8.5) and 47.1 (6.1) ml x kg(-1) x min(-1) [mean (SD)] in the adults and children, respectively (P > 0.05). Relative to VO2max, Thvent was 61.7 (5.3)% in the adults and 64.7 (5.2)% in the children (P > 0.05). Overall, leg, and chest RPE values at Thvent for the adults were 11.5 (2.6), 11.9 (2.5), and 10.5 (2.5), while for the children these values were 13.6 (2.2), 14.1 (2.2), and 12.6 (2.3), respectively. All RPE values were higher for the children (P < 0.05). These results suggest that children are able to discriminate levels of exertion in different parts of their body during graded exercise. Furthermore, children rate an intensity corresponding to Thvent to require a greater overall, leg and chest effort than adults exercising at a similar intensity. This indicates that children experience more pronounced cardiorespiratory and muscular sensations during this type of exercise.

The purpose of this study was to examine the influence of body fatness, aerobic and anaerobic ability on 3-km running performance in 19 physically active boys (mean +/- SD, age = 10.4 +/- 0.9 yrs). The sum of six skinfolds, VO2 at 8.04 and 9.65 km.hr-1, and VO2max were measured in the laboratory. Run time for 3 km was assessed twice on separate days on a 200-meter indoor track. Prior to each run, every child performed two 55-meter sprints and two vertical jumps. Mean +/- SD values for the sum of skinfolds, %VO2max at each running speed, VO2max and 3-km run time were: 33.9 +/- 14.9 mm; 70.6 +/- 6.6% and 81.0 +/- 7.9%; 54.6 +/- 5.0 ml.kg-1.min-1; 16.41 +/- 2.58 min, respectively. Significant (p < 0.05) correlations were observed between the following variables and run time: sum of skinfolds (r = 0.72); vertical jump (r = 0.67); sprint time (r = 0.59); VO2max (r = 0.61); and, %VO2max at each treadmill speed (r = 0.79 and r = 0.75, respectively). Stepwise multiple regression analysis indicated that the combination of the %VO2max at 8.04 km.hr-1 and vertical jump accounted for 83% (adjusted R2) of the variance in running time (SEE = 1.06 min, p < 0.05). This study suggests that 3-km run time in physically active boys is influenced by aerobic and anaerobic indices as well as body fatness, supporting the notion that children, compared to adults, are not metabolic specialists.

The purpose of this study was to examine serum and salivary cortisol responses to cycling exercise in male children, 10.6 +/- 0.2 yr (mean +/- SE). Each child performed a graded exercise test on a cycle ergometer to determine VO2max. On a separate day, a 30-min bout of exercise at 70% of VO2max was performed. Blood, obtained from a venous catheter, and saliva samples were collected at rest, at 15 and 30 min of exercise, and 15 min post-exercise. The mean serum cortisol level at 15 min (7.94 +/- 1.43 micrograms.dl-1) and 30 min (8.72 +/- 1.77 micrograms.dl-1) of exercise and at 15 min post-exercise (8.21 +/- 1.59 micrograms.dl-1) were significantly greater than rest (5.54 +/- 0.86 micrograms.dl-1). The increase in salivary cortisol levels over time approached (P = 0.08), but did not reach significance. However, effect size analyses indicated that the increase in salivary cortisol at 30 min of exercise (0.64) and 15 min post-exercise (0.62) was similar to the change in serum cortisol at these same two time points (0.72 and 0.66, respectively). Serum and salivary cortisol were correlated (P < 0.05) at 15 min of exercise (r = 0.77), 30 min of exercise (r = 0.90), and 15 min post-exercise (r = 0.84), but not at rest (r = 0.46). In conclusion, 30 min of submaximal exercise at 70% of VO2max significantly increased serum cortisol level; and salivary and serum cortisol are correlated during and after exercise.

This study examined the effects of a 14-week running program on VO2max, as well as cardiac output (Q) and arterial-venous O2 difference (a-vO2 dif) at submaximal intensities corresponding to 50 and 75% of VO2max. Thirteen boys (mean age 10.6 +/- 1.2 yrs) served as experimental subjects while 13 other boys of similar age (mean age 10.2 +/- 1.2 yrs) served as controls. Mean VO2max in the runners increased 13%, from 44.2 +/- 7.0 to 49.9 +/- 6.3 ml.kg-1.min-1. Posttraining VO2 during submaximal and maximal exercise was significantly (p < 0.05) greater in the runners than in the controls. Q and SV exhibited an increase of 10% at each intensity, but posttraining differences between groups were not significant (p > 0.05). A-vO2 dif increased by 8% at 50% of VO2max and by 6% at 75% of VO2max, and was significantly greater in the runners following training. These results indicate that increases in submaximal relative VO2 in children are mediated by increases in a-vO2 dif and Q.

The purpose of this investigation was to assess the validity of a 500-yard shallow water run test to determine peak aerobic power (VO2peak) and to compare it with the commonly used 1.5-mile run test. Subjects included 15 men and 28 women who completed two trials each of a 500-yard shallow water run test and a 1.5-mile run and then completed a graded exercise test on a treadmill to determine VO2peak. Correlation coefficients with measured VO2peak were -0.89 and -0.80 for the 1.5-mile and 500-yard water runs, respectively. Multiple regression analyses revealed that prediction of VO2peak from 1.5-mile run time was significantly improved by including the 1.5-mile run peak HR (R2 = 0.82, SEE = 3.52 ml.kg-1.min-1). Similarly, for the 500-yard water run test, percent body fat and height were significant additional predictors of VO2peak (R2 = 0.86, SEE = 3.19 ml.kg-1.min-1). We conclude that the 500-yard shallow water run test, especially when used with the descriptive measures of percent body fat and height, can provide a reasonable estimate of an individuals' cardiorespiratory fitness classification. However, caution is advised when administering these tests in older populations or in those with multiple coronary risk factors.

The purpose of this study was to examine the reliability of the rating of perceived exertion (RPE), using the Borg 6-20 scale, at ventilatory threshold (VT) in children. Thirty children (19 male, 11 female) with a mean +/- SD age of 10.4 +/- 1.1 yrs performed two graded exercise tests for the assessment of VT and VO2max. RPE was recorded throughout each exercise test. There were no significant (p > 0.05) differences between the mean VO2max (50.9 +/- 6.0 vs 51.0 +/- 5.7 ml.kg-1.min-1; r = 0.95) or the mean VO2 at VT (36.2 +/- 4.4 vs 36.7 +/- 4.5 ml.kg-1.min-1; r = 0.87) between trials. The mean RPE at VT during trial 1 (12.4 +/- 2.7) was significantly higher than during trial 2 (11.4 +/- 3.3; p < 0.05). The test-retest reliability correlation for the RPE at VT was r = 0.78. The lower RPE in the second trial may have been due to a greater comfort and familiarity with the testing procedures. The reliability analysis indicates that the RPE at VT within a given child is fairly consistent from trial to trial. However, large inter-individual variability in the RPE at VT (range = 6 to 19) was noted and was not related to variations in the onset of VT. This raises some concern over the use of a given RPE value or range of RPE values in the regulation of exercise intensity for this age group. The test-retest reliability of VT and VO2max in this age group is similar to previous reports.

Twelve aerobically trained males (age 22 +/- 1.3 yr, range 18-31) were studied to determine the effects of VE and EMG feedback upon cardiorespiratory and muscular activity during one segment of a continuous 36-min bout of treadmill running just below ventilatory threshold (VT). Ventilatory, metabolic, cardiovascular, RPE, and EMG variables recorded during a 12-min feedback segment were compared with those observed during 12-min attentional distraction and control conditions. The three treatments were counterbalanced. Mean VO2 (2987 ml.min-1) remained constant across the three periods as did VCO2 (3102 ml.min-1), HR (168 bpm), RQ (0.95), and O2 pulse (18.5 ml.beat-1). However, VE was significantly reduced during feedback (Fb) as compared with both the distraction (D) and control (C) conditions (mean +/- SE: 83.2 +/- 3.6 vs 86.6 +/- 4.2 and 87.8 +/- 4.2 l.min-1, respectively). This effect was marked by a reduction in respiratory rate (RR) (41.1 +/- 2.1 vs 44.5 +/- 1.9 and 46.8 +/- 1.9 breaths.min-1 for Fb, D, and C, respectively) and an increase in tidal volume (TV) (2115 +/- 144 vs 1904 +/- 110 and 2020 +/- 102 ml.breath-1 for Fb, D, and C, respectively). These changes resulted in significant reductions in VE/VO2 (26.5 +/- 0.7 vs 28.9 +/- 1.0 and 28.3 +/- 0.9 ratio magnitudes), VE/VO2 (28.1 +/- 0.8 vs 30.2 +/- 1.0 and 29.7 +/- 1.0 ratio magnitudes), and PETO2 (105.5 +/- 1.0 vs 108.4 +/- 1.1 and 107.6 +/- 1.2 mm Hg) during Fb as compared with D and C, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

Whether the point of deflection from linearity of heart rate (HRD) coincides with ventilatory threshold (VT) has not been extensively examined in children. The purpose of this study was to assess the relationship between the VO 2 measured at VT and the VO 2 measured at HRD. Twenty-two boys with a mean age of 10.7 years (±1.0) performed a graded exercise test to determine VT, HRD, and VO 2 max. There was no significant difference between mean VO 2 (ml/kg/min) at VT and at HRD (33.5±3.5 vs. 34.1±4.4; p >0.05). Linear regression analysis revealed a correlation of r = 0.76 ( p <0.01) between the VO 2 measured at VT and the VO 2 measured at HRD. These results indicate that HRD may be an accurate predictor of VT in most but not all children, and caution should be used when interpreting the significance of HRD.

There are conflicting data with regard to the effect of endurance training in children. On the basis of this information, the effects of 8 wk of run training on ventilatory threshold (VT) and VO2max of eight male children were investigated. Children ranged in age from 10 to 14 yr, with a mean age of 12.4 yr. All subjects were previously untrained. Training consisted of running 4 d.wk-1 for a period of 8 wk. Continuous running was performed 2 d.wk-1 for 10-30 min at 70-80% of VO2max. Interval running was performed the remaining 2 d.wk-1. Repeated intervals of 100-800 m at 90-100% of VO2max were used in this phase of the training. The total distance run for this type of training was 1.5-2.5 km. Incremental treadmill testing prior to and after the training period indicated a 19.4% increase in VT from 30.5 to 36.4 ml.kg-1.min-1 (P less than 0.05). When VT was expressed as a percentage of VO2max, there was a significant (P less than 0.05) increase from 66.6% to 73.8%. VO2max increased 7.5% from 45.9 to 49.4 ml.kg-2.min-2 (P less than 0.05). None of these changes was noted in eight age- and size-matched children who served as control subjects. The results of this study indicate that 8 wk of endurance running training which is of sufficient frequency, intensity, and duration can significantly improve VT and aerobic capacity in male children.

Coronary heart disease (CHD) is now recognised as a paediatric problem despite the fact that clinical symptoms of this disease do not become apparent until much later in life. Epidemiological studies of risk factors in children have now been conducted. These studies suggest that the risk factors for cardiovascular disease in adults, which include a family history of heart disease, elevated blood lipids (serum cholesterol and triglycerides), obesity, hypertension, smoking, diabetes mellitus and inadequate physical activity, can be identified in children. Several investigators have reported the existence of one or more risk factors in more than 50% of the children they have examined. It is now clear that we can detect most children who are potentially at risk for CHD. The notion of 'tracking' some of the most common CHD risk factors in children has been used in several studies. Results from this type of research indicate that children who are at the extreme end of the distribution and have high levels of blood pressure, adverse lipid levels and are obese will continue to exhibit these coronary risk factors as they grow. The research completed at present does not answer the question of whether children who exhibit a coronary-prone risk factor profile will exhibit this same profile at an age when one is most likely to develop the clinical manifestations of CHD. It does make sense, however, to identify those children who may be at risk for developing premature CHD and to initiate safe interventions such as behaviour modification, changes in diet and increases in physical activity. These have all been shown to alter risk factors which are associated with increased relative risk of CHD in adults. It should be noted that in adults regular aerobic exercise often may alter all risk factors for CHD, including hypertension and diabetes. Whether regular aerobic exercise will induce similar changes in children is not fully understood.