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Your search keyword '"Mahlknecht, Jürgen"' showing total 343 results
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343 results on '"Mahlknecht, Jürgen"'

1. Optical Biosensors and Their Applications for the Detection of Water Pollutants

Author

Herrera-Domínguez, Marcela, Morales-Luna, Gesuri, Mahlknecht, Jürgen, Cheng, Quan, Aguilar-Hernández, Iris, and Ornelas-Soto, Nancy

Subjects
Analytical Chemistry, Chemical Sciences, Water Pollutants, Biosensing Techniques, Surface Plasmon Resonance, Molecularly Imprinted Polymers, Environmental Pollutants, optical biosensors, water pollutants, water monitoring, interferometers, resonators, SPR biosensor, fiber optic biosensors, emerging contaminants, heavy metals in water, waterborne pathogens, Biochemistry and Cell Biology, Biochemistry and cell biology, Analytical chemistry
Abstract

The correct detection and quantification of pollutants in water is key to regulating their presence in the environment. Biosensors offer several advantages, such as minimal sample preparation, short measurement times, high specificity and sensibility and low detection limits. The purpose of this review is to explore the different types of optical biosensors, focusing on their biological elements and their principle of operation, as well as recent applications in the detection of pollutants in water. According to our literature review, 33% of the publications used fluorescence-based biosensors, followed by surface plasmon resonance (SPR) with 28%. So far, SPR biosensors have achieved the best results in terms of detection limits. Although less common (22%), interferometers and resonators (4%) are also highly promising due to the low detection limits that can be reached using these techniques. In terms of biological recognition elements, 43% of the published works focused on antibodies due to their high affinity and stability, although they could be replaced with molecularly imprinted polymers. This review offers a unique compilation of the most recent work in the specific area of optical biosensing for water monitoring, focusing on both the biological element and the transducer used, as well as the type of target contaminant. Recent technological advances are discussed.

Published
2023

10. Acquired insights from the long-term surveillance of SARS-CoV-2 RNA for COVID-19 monitoring: The case of Monterrey Metropolitan Area (Mexico)

Author

Padilla-Reyes, Diego A, Álvarez, Mario Moises, Mora, Abrahan, Cervantes-Avilés, Pabel A, Kumar, Manish, Loge, Frank J, and Mahlknecht, Jürgen

Subjects
Biological Sciences, Environmental Sciences, Chemical Sciences, Prevention, Infectious Diseases, Emerging Infectious Diseases, Infection, Good Health and Well Being, COVID-19, Humans, Mexico, RNA, Viral, SARS-CoV-2, Wastewater, Surveillance, Epidemiology, RT-qPCR, Toxicology, Biological sciences, Chemical sciences, Environmental sciences
Abstract

Wastewater-based epidemiology offers a time- and cost-effective way to monitor SARS-CoV-2 spread in communities and therefore represents a complement to clinical testing. WBE applicability has been demonstrated in a number of cases over short-term periods as a method for tracking the prevalence of SARS-CoV-2 and an early-warning tool for predicting outbreaks in the population. This study reports SARS-CoV-2 viral loads from wastewater treatment plants (WWTPs) and hospitals over a 6-month period (June to December 2020). Results show that the overall range of viral load in positive tested samples was between 1.2 × 103 and 3.5 × 106 gene copies/l, unveiling that secondary-treated wastewaters mirrored the viral load of influents. The interpretation suggests that the viral titers found in three out of four WWTPs were associated to clinical COVID-19 surveillance indicators preceding 2-7 days the rise of reported clinical cases. The median wastewater detection rate of SARS-CoV-2 was one out of 14,300 reported new cases. Preliminary model estimates of prevalence ranged from 0.02 to 4.6% for the studied period. This comprehensive statistical and epidemiological analysis demonstrates that the applied wastewater-based approach to COVID-19 surveillance is in general consistent and feasible, although there is room for improvements.

Published
2022

20. Prevalence of pharmaceuticals and personal care products, microplastics and co-infecting microbes in the post-COVID-19 era and its implications on antimicrobial resistance and potential endocrine disruptive effects

Author

Kumar, Manish, Mazumder, Payal, Silori, Rahul, Manna, Suvendu, Panday, Durga Prasad, Das, Nilotpal, Sethy, Susanta Kumar, Kuroda, Keisuke, Mahapatra, Durga Madhab, Mahlknecht, Jürgen, Tyagi, Vinay Kumar, Singh, Rajesh, Zang, Jian, and Barceló, Damià

Published
2023
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27. Land-Use Optimization for Sustainable Agricultural Water Management in Pajaro Valley, California

Author

Garza-Díaz, Laura E, DeVincentis, Alyssa J, Sandoval-Solis, Samuel, Azizipour, Mohamad, Ortiz-Partida, J Pablo, Mahlknecht, Jürgen, Cahn, Michael, Medellín-Azuara, Josué, Zaccaria, Daniele, and Kisekka, Isaya

Subjects
Life on Land, Zero Hunger, Water management, Groundwater, Agriculture, Simulation-optimization model, Aquifer storage, Sustainability, Civil Engineering, Environmental Engineering, Applied Economics
Abstract

The uncertainty of water resources availability is a growing problem in California as agricultural industrialization, population growth, and climate change affect water resources. The intense manipulation of the hydrological regime has led to the depletion of the water resources in the state and the subsequent use of various adaptive management strategies to cope with environmental conditions and social concerns. The historical imbalance between water pumping and replenishment in Pajaro Valley has led to overdrafted aquifers, seawater intrusion, and salinization. The objective of this study is to estimate the sustainable carrying capacity of agricultural land in Pajaro Valley while preventing groundwater overdraft. A groundwater box model was built and calibrated using historical data to represent current and future hydrology and water management strategies. An optimization model maximized the economic profit using the agricultural acreage as the decision variable with a set of constraints aimed at determining the sustainable carrying capacity of the groundwater basin. Model constraints include total land and water availability, crop acreage, agricultural water use, and historical demand. In the Pajaro Valley, agricultural operations must use less water more efficiently, which means changes in crop types, size of activities, and fallowing land in parts of the basin. Results of the optimal scenario over 25 years show a 15% reduction of total agricultural acreage, 8.5% reduction in food production, average profit loss of 4%, and a 79% reduction in aquifer depletion. This study provides an overall vision of what can be accomplished with coordinated land use planning using strategies that harmonize individual decisions and shared natural resources.

Published
2019

45. Desarrollo sostenible a través del nexo agua-energía-alimentos: avances y perspectivas para México

Author

Mahlknecht, Jürgen and Mahlknecht, Jürgen

Abstract

The Water-Energy-Food Nexus and its outlook for Mexico are being assessed. To achieve this goal, a literature review of recent advancements is conducted, and the fundamental interrelationships in the country are quantified and illustrated. The results demonstrate that the Nexus serves as a valuable framework for implementing strategies and actions related to achieving the Sustainable Development Goals. There are some local studies focused on generating optimization models and performance indices to evaluate the current state and project future scenarios. However, to implement the nexus successfully, this country requires a redesign of public policies, as well as coordinated planning across the involved sectors, including the active participation of stakeholders from society, business, and academia, Se evalúa el nexo agua-energía-alimentos y su perspectiva para México. Para este propósito, se emplea una revisión bibliográfica de los últimos avances y se cuantifican e ilustran las interrelaciones fundamentales en el país. Los resultados muestran que el nexo es un marco útil para aplicar estrategias y acciones referentes al cumplimiento de los Objetivos de Desarrollo Sustentable. Existen algunos estudios locales orientados a la generación de modelos de optimización e índices de desempeño para evaluar el estado actual y proyectar escenarios futuros. Sin embargo, para poder implementar el nexo, este país requiere un rediseño de las políticas públicas, así como una planificación coordenada de los sectores involucrados, incluida la participación de las partes interesadas de la sociedad, las empresas y la academia.

Published
2024

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