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26 results on '"Maher, Eslam"'

5. Plasma miRNA expression profile in pediatric pineal pure germinomas

Author

Fakhry, Mona, primary, Elayadi, Moatasem, additional, Elzayat, Mariam G., additional, Samir, Omar, additional, Maher, Eslam, additional, Taha, Hala, additional, El-Beltagy, Mohamed, additional, Refaat, Amal, additional, Zamzam, Manal, additional, Abdelbaki, Mohamed S., additional, Sayed, Ahmed A., additional, Kieran, Mark, additional, and Elhaddad, Alaa, additional

Published
2024
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11. Prognostic factors affecting infantile medulloblastoma outcomes in the molecular era: a 12-year single-center experience from Egypt

Author

El-Hemaly, Ahmed, primary, El-Ayadi, Moatasem, additional, Ahmed, Soha, additional, Taha, Hala, additional, Magdy, Marwa, additional, Refaat, Amal, additional, Ammar, Hany, additional, Maher, Eslam, additional, Badawy, Eman, additional, Rady, Mohamed, additional, El-Beltagy, Mohamed, additional, Zaghloul, Mohamed S, additional, and El-Haddad, Alaa, additional

Published
2023
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13. miRNA Expression Profile in Pediatric Pineal Pure Germinomas

Author

Fakhry, Mona, primary, Elayadi, Moatasem, additional, Elzayat, Mariam, additional, Samir, Omar, additional, Maher, Eslam, additional, Taha, Hala, additional, El-Beltagy, Mohamed, additional, Refaat, Amal, additional, Zamzam, Manal, additional, Abdelbaki, Mohamed S, additional, Sayed, Ahmed, additional, Kieran, Mark, additional, and Elhaddad, Alaa, additional

Published
2022
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19. EPEN-50. THE MANAGEMENT AND TREATMENT OF PEDIATRIC SPINAL CORD EPENDYMOMA: RESULTS FROM A COLLABORATIVE INTERNATIONAL MULTI-INSTITUTIONAL REVIEW

Author

Lucas, John, primary, Kumirova, Ella, additional, Tsang, Derek, additional, Vinitsky, Anna, additional, Chiang, Jason, additional, Hazrati, Lili-Naz, additional, Lane, Shelby, additional, Agbahiwe, Harold, additional, Upadhyay, Santhosh, additional, Tinkle, Christopher, additional, Konovalov, Dmitry, additional, El-Ayadi, Moatasem, additional, Maher, Eslam, additional, Emtsova, Victoria, additional, Nechesnyuk, Alexey, additional, Sarhan, Nasim, additional, Loginova, Anna, additional, Hsu, Chih-Yang, additional, Ladra, Matthew, additional, Terezakis, Stephanie, additional, Boop, Frederick, additional, Klimo, Paul, additional, Ahmed, Soha, additional, Laperriere, Normand, additional, Ramaswamy, Vijay, additional, and Merchant, Thomas, additional

Published
2020
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25. THE MANAGEMENT AND TREATMENT OF PEDIATRIC SPINAL CORD EPENDYMOMA: RESULTS FROM A COLLABORATIVE INTERNATIONAL MULTI-INSTITUTIONAL REVIEW

Author

John Lucas Jr., Kumirova, Ella, Tsang, Derek, Vinitsky, Anna, Chiang, Jason, Hazrati, Lili-Naz, Lane, Shelby, Agbahiwe, Harold, Upadhyay, Santhosh, Tinkle, Christopher, Konovalov, Dmitry, El-Ayadi, Moatasem, Maher, Eslam, Emtsova, Victoria, Nechesnyuk, Alexey, Sarhan, Nasim, Loginova, Anna, Hsu, Chih-Yang, Ladra, Matthew, Terezakis, Stephanie, Boop, Frederick, Klimo, Paul, Ahmed, Soha, Laperriere, Normand, Ramaswamy, Vijay, and Merchant, Thomas

26. Epidemiology and clinical outcomes of childhood central nervous system cancers in a large low-middle income country pediatric oncology center: a report on 5051 kids.

Author

Maher E, Kamal M, El-Ayadi M, Refaat A, Enayet A, El-Beltagy M, Eldebawy E, Taha H, Awad M, and Zaghloul MS

Abstract

Background: Central nervous system (CNS) tumors are the leading cause of cancer-related deaths in children. While most cases come from low-middle income countries (LMIC) where their prognosis is worse, few epidemiological studies are conducted in these regions., Methods: We conducted a registry-based cohort study for childhood CNS tumors at Children's Cancer Hospital, Egypt (CCHE) over 15 years. Unified treatment protocols are implemented. Survival analyses were conducted using the Kaplan-Meier function. Cases were additionally annotated using the ICCC-3 classification., Results: In total, 5051 children ≤ 18 years old were identified, accounting for 20% of all childhood cancers treated at CCHE. The most common tumor sites were the posterior fossa (36.8%) and the brainstem (17.7%). Pathologies were predominantly astrocytic (n=1360; 26.9%) and embryonal (n=1003; 19.9%) in origin. The 5yr OS and EFS for all cases were 64.6% and 51.8%, respectively. More specifically, 1421 low-grade gliomas were identified, with 5yr OS = 91.1%. Medulloblastoma (n=801) recorded a 5yr OS of 66%. The entity with the worst prognosis was DIPG (n=633) with 5yr OS = 3.2%., Conclusions: We report on a large number of childhood CNS tumors from a LMIC. This study underscores the need to understand the burden of childhood brain tumors and its outcomes in resource-constrained settings., Impact: This study reports on the epidemiology and clinical outcomes of 5000+ children with CNS tumors from a specialized LMIC center. Despite the lack of many sophisticated and advanced facilities, LMIC can improve the clinical end results with experience and augmented efforts.

Published
2024
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