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Dengue fever had been a global health problem for over five decades, especially in tropical and subtropical countries. It was caused by a viral infection that spread from mosquito to human. Natural sources had the potential to serve as an alternative therapy for dengue fever, such as Psidium guajava L. Its leaves contained several compounds and exhibited various bioactivities. This research aimed to explore the potential of Psidium guajava as an additional therapy for dengue fever patients. The method used was a narrative literature review that searched literature in primary data sources such as national and international journals through databases like PubMed and Scopus. The results reported that quercetin was one of the compounds found in Psidium guajava that affected dengue fever. It suppressed the intracellular replication of dengue virus type 2 (DENV-2) and inhibited ATPase in DENV-4. Additionally, quercetin also stimulated stem cell factors in bone marrow stromal cells to produce thrombopoietin, which functioned to regulate platelet production in the spinal cord. Thus, Psidium guajava had the potential and effectiveness to be used as an alternative therapy for dengue fever. [ABSTRACT FROM AUTHOR]

Stress is any kind of change that causes physical, emotional or psychological strain. Aromatherapy is one of the complementary therapies used as an alternative treatment to relax the body and influence emotional regulation, reduce stress and anxiety that can affect a person's sleep quality. This research was conducted to show that the use of aromatherapy is able to control anxiety and stress in a person at a productive age. Data of this research was obtained through an online questionnaire (Google Form) using the accidental sampling method. The questionnaire was tested for face and content validities on 15 respondents who met the inclusion criteria before being used to collect data. Construct validity and reliability using data from 110 respondents stated that all question items were valid and reliable. The population of this study was Surabaya residents and aged 15-64 years (productive age). The inclusion criteria for this research sample were being of productive age (aged 15-64 years), willing to fill out a questionnaire, and domiciled in Surabaya.The total number of respondents was 110. The scoring method used four answer options, with 4 differentscores. Aromatherapy was declared effective for reducing stress if the total score was 26-40 and ineffective if the total score was 10-25. The results of this study stated that aromatherapy was an alternative and complementary treatment to reduce mild stress, as evidenced by the 85 respondents who used aromatherapy, 78 respondents (91.78%) stated that aromatherapy played an effective role, while 7 other respondents (8.24%) stated that aromatherapy was not effective for reducing stress. Meanwhile, the level of knowledge related to the ability of aromatherapy to reduce stress in 25 respondents who had never used aromatherapy, 9 respondents (36%) had a good level of knowledge, 5 respondents (20%) had a sufficient level of knowledge, and 11 respondents (44%) had a poor level of knowledge. Therefore, there is a need for health promotion to the community regarding aromatherapy as an alternative treatment and complementary therapy in reducing stress. [ABSTRACT FROM AUTHOR]