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143 results on '"Magner D"'

5. A new system of training horses;

Author

Magner, D. (Dennis), 1833, Library of Congress, and Magner, D. (Dennis), 1833

Subjects
Horses, Training
Published
1863

10. The new system of educating horses;

Author

Magner, D. (Dennis), 1833, Library of Congress, and Magner, D. (Dennis), 1833

Subjects
Diseases, Horses, Training
Published
1877

14. The art of taming and educating the horse : a system that makes easy and practical the subjection of wild and vicious horses ... : the simplest, most humane and effective in the world : with details of management in the subjection of over forty representative vicious horses, and the story of the author's personal experience : together with chapters on feeding, stabling, shoeing ... /

Author

Magner, D. (Dennis), 1833, University of Pennsylvania Libraries (archive.org), and Magner, D. (Dennis), 1833

Subjects
CHR 1887, Diseases, Horses, PRO Smith, James Somers, Jr. (donor), Training
Published
1887

18. The art of taming and educating the horse : with details of management in the subjection of over forty representative vicious horses, and the story of the author's personal experience : together with chapters on feeding, stabling, shoeing, and the practical treatment for sickness, lameness, etc. : with a large number of recipes /

Author

Magner, D. (Dennis), 1833, Webster Family Library of Veterinary Medicine (archive.org), and Magner, D. (Dennis), 1833

Subjects
Diseases, Horses
Published
1886

32. Hydrostatic transmissions are evolving: manufacturers of HSTs are embracing the efficiency of electrohydraulic controls, as machines become more versatile

Author

Rodgers, R., Horvat, B., Sturtz, A., and Magner, D.

Subjects
Business, Engineering and manufacturing industries
Abstract

Hydrostatic transmission (HST) is a term referring to a closed-circuit pump and motor system where the pump is generally of variable-displacement, axial-piston design. The motor, or motors, can be fixed [...]

Published
2005

34. A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity

Author

Wollam, J., Magner, D., Magomedova, L., Rass, E., Shen, Y., Rottiers, V., Habermann, B., Cummins, C., and Antebi, A.

Subjects
QH301-705.5, Biology (General)
Abstract

Endogenous small molecule metabolites that regulate animal longevity are emerging as a novel means to influence health and life span. In C. elegans, bile acid-like steroids called the dafachronic acids (DAs) regulate developmental timing and longevity through the conserved nuclear hormone receptor DAF-12, a homolog of mammalian sterol-regulated receptors LXR and FXR. Using metabolic genetics, mass spectrometry, and biochemical approaches, we identify new activities in DA biosynthesis and characterize an evolutionarily conserved short chain dehydrogenase, DHS-16, as a novel 3-hydroxysteroid dehydrogenase. Through regulation of DA production, DHS-16 controls DAF-12 activity governing longevity in response to signals from the gonad. Our elucidation of C. elegans bile acid biosynthetic pathways reveals the possibility of novel ligands as well as striking biochemical conservation to other animals, which could illuminate new targets for manipulating longevity in metazoans.

Published
2012

35. The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity

Author

Wollam, J., Magomedova, L., Magner, D., Shen, Y., Rottiers, V., Motola, D., Mangelsdorf, D., Cummins, C., and Antebi, A.

Abstract

Bile acids are cholesterol-derived signaling molecules that regulate mammalian metabolism through sterol-sensing nuclear receptor transcription factors. In C. elegans, bile acid-like steroids called dafachronic acids (DAs) control developmental timing and longevity by activating the nuclear receptor DAF-12. However, little is known about the biosynthesis of these molecules. Here, we show that the DAF-36/Rieske oxygenase works at the first committed step, converting cholesterol to 7-dehydrocholesterol. Its elucidation as a cholesterol 7-desaturase provides crucial biochemical evidence that such oxygenases are key steroidogenic enzymes. By controlling DA production, DAF-36 regulates DAF-12 activities for reproductive development and longevity and may illuminate related pathways in metazoans.

Published
2011

38. Esomeprazole 40mg Capsules are Bioequivalent when Administered Intact or as the Contents Mixed with Applesauce.

Author

Andersson, T., Magner, D., Patel, J., Rogers, P., and Levine, J.G.

Subjects
*DRUGS, *APPLESAUCE
Abstract

Objective: This study was conducted to determine whether administration of the contents of an open capsule of esomeprazole (enteric-coated pellets) 40mg with applesauce is bioequivalent to administration of an intact capsule in healthy volunteers. Participants and Study Design: 45 adult male and female volunteers participated in this randomised, single-dose, nonblinded, two-way crossover study conducted at a single centre. Results: 41 volunteers completed the trial. Time to maximum plasma concentration (C) for esomeprazole (t) was approximately 2.4 hours and elimination half-life (t) was approximately 0.9 hours by either mode of administration. The ratios of the geometric means for C and area under the plasma concentration-time curve (AUC) for capsule contents with applesauce relative to intact capsule were 0.93 (90% confidence interval [CI]: 0.86 to 1.01) and 0.99 (90% CI: 0.94 to 1.04), respectively. The finding that the 90% CIs were within 0.80 to 1.25 for both parameters indicates bioequivalence. Esomeprazole was well tolerated by the study group irrespective of mode of administration. Conclusions: Esomeprazole is bioequivalent when administered either as an intact capsule or as the contents of a capsule mixed with applesauce in healthy volunteers. This latter alternative mode of administration may provide benefits to patients who have difficulty swallowing. [ABSTRACT FROM AUTHOR]

Published
2001
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39. The new system of educating horses, including instructions on feeding, watering, etc. Also how shoeing should be done: with simple practical treatment for diseases. Illustrated. Including a large number of valuable recipes not before published. By D. Magner ...

Author

Magner, D. (Dennis), b. 1833., Magner, D. (Dennis), b. 1833., Magner, D. (Dennis), b. 1833., and Magner, D. (Dennis), b. 1833.

Abstract

156 p. illus. 19cm., Making of America (MOA), (dlps) AJS0492.0001.001, (lccallno) SF 287 .M2 1870, http://quod.lib.umich.edu/t/text/accesspolicy.html

40. The new system of educating horses, including instructions on feeding, watering, etc. Also how shoeing should be done: with simple practical treatment for diseases. Illustrated. Including a large number of valuable recipes not before published. By D. Magner ...

Author

Magner, D. (Dennis), b. 1833., Magner, D. (Dennis), b. 1833., Magner, D. (Dennis), b. 1833., and Magner, D. (Dennis), b. 1833.

Abstract

156 p. illus. 19cm., Making of America (MOA), (dlps) AJS0492.0001.001, (lccallno) SF 287 .M2 1870, http://quod.lib.umich.edu/t/text/accesspolicy.html

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