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[Abstract]: Background Femoroacetabular impingement (FAI) is considered one of the main causes of hip osteoarthritis in young adults, especially in athletes. In recent years, morphological changes in FAI in the hip have been linked to early and intense sports participation, but studying top-level athlete samples is not easy. This paper presents the prevalence of FAI radiological markers in 120 active white male professional football players in the Spanish First Division League (La Liga) and compares the morphological changes with those of a control group of healthy individu‑ als without signifcant sport activity. Methods The precontract medical evaluation hip X-rays of 120 white male professional football players from four diferent First Division Spanish football teams were prospectively fled and retrospectively reviewed by a dedicated skeletal radiologist. The footballers’ hip X-rays were compared with those of a control group of 80 healthy individuals (age-sex matched) without signifcant sport activity (obtained from routine work medical checks). Results The femoral head-neck deformity associated with the Cam type of femoroacetabular impingement was observed in 61.6% of professional football players and only in 11.6% of the control group (p <0.01). The presence of“herniation pit” (11.6%) and os acetabuli (13.3%) also reached statistical signifcance in the professional football play‑ ers group. In the other analyzed parameters, no statistically signifcant diferences between the groups were observed. Conclusions White professional top-level football players have an increased incidence of abnormal lateral epiphyseal extension ("pistol grip deformity"), os acetabuli and herniation pits

The genetic profile that is needed to identify talents has been studied extensively in recent years. The main objective of this investigation was to approach, for the first time, the study of genetic variants in several polygenic profiles and their role in elite endurance and professional football performance by comparing the allelic and genotypic frequencies to the non-athlete population. In this study, genotypic and allelic frequencies were determined in 452 subjects: 292 professional athletes (160 elite endurance athletes and 132 professional football players) and 160 non-athlete subjects. Genotyping of polymorphisms in liver metabolisers (CYP2D6, GSTM1, GSTP and GSTT), iron metabolism and energy efficiency (HFE, AMPD1 and PGC1a), cardiorespiratory fitness (ACE, NOS3, ADRA2A, ADRB2 and BDKRB2) and muscle injuries (ACE, ACTN3, AMPD1, CKM and MLCK) was performed by Polymerase Chain Reaction-Single Nucleotide Primer Extension (PCR-SNPE). The combination of the polymorphisms for the “optimal” polygenic profile was quantified using the genotype score (GS) and total genotype score (TGS). Statistical differences were found in the genetic distributions between professional athletes and the non-athlete population in liver metabolism, iron metabolism and energy efficiency, and muscle injuries (p<0.001). The binary logistic regression model showed a favourable OR (odds ratio) of being a professional athlete against a non-athlete in liver metabolism (OR: 1.96; 95% CI: 1.28–3.01; p = 0.002), iron metabolism and energy efficiency (OR: 2.21; 95% CI: 1.42–3.43; p < 0.001), and muscle injuries (OR: 2.70; 95% CI: 1.75–4.16; p < 0.001) in the polymorphisms studied. Genetic distribution in professional athletes as regards endurance (professional cyclists and elite runners) and professional football players shows genetic selection in these sports disciplines.

Saint John the Baptist was Christ's greatest prophet. Pointing to his staff, he is depicted as "the voice in the wilderness" who prepared the way for the Lord, as described in the New Testament. His primitive garment of camel's skin and his bony appearance speak to his ascetic life in the desert, where he preached repentance to prepare for the coming of Christ. His eyes appear large, as the flesh of his face is sunken. The saint's bodily neglect has contributed to his sanctity, symbolized by the splendidly tooled gold background. His name is written in his halo, and on his scroll can be read in Latin the words that he exclaimed upon seeing Jesus: "Behold the Lamb of God." The panel was originally one of the side panels of a polyptych (altarpiece made of several panels).; [Translation] Behold the Lamb of God, Please note that if this image is under copyright, you may need to contact one or more copyright owners for any use that is not permitted under the ARTstor Terms and Conditions of Use or not otherwise permitted by law. While ARTstor tries to update contact information, it cannot guarantee that such information is always accurate. Determining whether those permissions are necessary, and obtaining such permissions, is your sole responsibility.

Dos cartas de Antonio Maestro, fechadas en Villalonso en 1765, la primera el 19 de julio (h. 264r-265v) y el 9 de agosto (h. 266r/v) y un informe de Diego Rafael Pinto, del 26 de noviembre de 1797 (h. 267r-268r), en respuesta a la solicitud de Tomás López, V.a. descripción del mapa en Mss/7312(H.269R), Autógrafos con firma, Biblioteca Nacional (España). Gabinete de Manuscritos, Índice de las relaciones geográficas enviadas a Tomás López que se conservan en el Gabinete de Manuscritos de la Biblioteca Nacional; introducción y elaboración de Clotilde Olarán Múgica. Madrid, 2004, Dos cartas de Antonio Maestro, fechadas en Villalonso en 1765, la primera el 19 de julio (h. 264r-265v) y el 9 de agosto (h. 266r/v) y un informe de Diego Rafael Pinto, del 26 de noviembre de 1797 (h. 267r-268r), en respuesta a la solicitud de Tomás López, Forma parte de las Relaciones geográficas de Tomás López, El informe en papel timbrado, En blanco la h. 268v