517 results on '"Maekawa, Tsuyoshi"'
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2. Prognostic Significance of the Difference Between Mixed and Jugular Venous Oxygen Saturation After Severe Traumatic Brain Injury: A Post Hoc Analysis of the Brain Hypothermia Study
3. Discovery of novel 5-oxa-2,6-diazaspiro[3.4]oct-6-ene derivatives as potent, selective, and orally available somatostatin receptor subtype 5 (SSTR5) antagonists for treatment of type 2 diabetes mellitus
4. Discovery of novel somatostatin receptor subtype 5 (SSTR5) antagonists: Pharmacological studies and design to improve pharmacokinetic profiles and human Ether-a-go-go-related gene (hERG) inhibition
5. Post-hepatectomy tolvaptan-induced hypernatremia in a hepatocellular carcinoma patient with cirrhosis: a case report
6. Improvement of nursing workload by a novel user- aimed assessment software in a tertiary care hospital
7. Temperature difference between jugular bulb and pulmonary artery is associated with neurological outcome in patients with severe traumatic brain injury: A post hoc analysis of a brain hypothermia study
8. Plasma Potassium Concentration on Admission Correlates with Neurologic Outcome in Traumatic Brain Injury Patients Treated with Targeted Temperature Management: A Post Hoc Analysis of a Multicenter Randomized Controlled Trial
9. Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel non-basic 1-(2H-indazole-5-yl)pyridin-2(1H)-one derivatives and mitigation of mutagenicity in Ames test
10. Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel 1-(1H-benzimidazol-6-yl)pyridin-2(1H)-one derivatives and design to avoid CYP3A4 time-dependent inhibition
11. Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities
12. A Randomized Controlled Trial of Therapeutic Hypothermia in Severe Head-Injured Patients in Japan: Overview of the Protocol
13. Management of Patients with Traumatic Brain Injury: Hypothermia Therapy and the Importance of Temperature Management
14. Hypothermia May Attenuate Not Only Interleukin-6 but also Matrix Metalloproteinase-9 of Systemic and Internal Jugular Blood from the Inflammatory Response to Traumatic Brain Injury in Humans
15. Hypothermia Prolongs Survival Time of Severely Septic Rats: A Study Using a Computer-Supported Multichannel Thermoregulatory System
16. Mild decrease in heart rate during early phase of targeted temperature management following tachycardia on admission is associated with unfavorable neurological outcomes after severe traumatic brain injury: a post hoc analysis of a multicenter randomized controlled trial
17. Slow rewarming improved the neurological outcomes of prolonged mild therapeutic hypothermia in patients with severe traumatic brain injury and an evacuated hematoma
18. Hemodynamic Efficacy of Neuroleptanesthesia for Therapeutic Hypothermia in Acute Brain Injury
19. Mild Hypothermia Therapy for Severe Acute Brain Insults in Clinical Practice
20. Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims: A pilot study
21. A new class of non-thiazolidinedione, non-carboxylic-acid-based highly selective peroxisome proliferator-activated receptor (PPAR) γ agonists: Design and synthesis of benzylpyrazole acylsulfonamides
22. A Survey on Power Outage-related Information Use Cases in the Event of a Disaster
23. Design, Synthesis, and Biological Evaluation of a Novel Series of 4-Guanidinobenzoate Derivatives as Enteropeptidase Inhibitors with Low Systemic Exposure for the Treatment of Obesity
24. Peak value of blood myoglobin predicts acute renal failure induced by rhabdomyolysis
25. Real-time monitoring of heart rate variability in critically ill patients
26. Increase in plasma glucagon, a factor in hyperglycemia, is related to neurological outcome in postcardiac-arrest patients
27. Prevalence and associated factors for delirium in critically ill patients at a Japanese intensive care unit
28. Cholinergic agonist physostigmine suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in rats with forebrain ischemia/reperfusion
29. Moderate hypothermia suppresses jugular venous superoxide anion radical, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats
30. Hyperglycemia enhances excessive superoxide anion radical generation, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats
31. Effects of Dichloroacetate on Survival Rate, Brain ATP, Lactate, and Water Content Following Cerebral Ischemia in Spontaneously Hypertensive Rats
32. Elevation of jugular venous superoxide anion radical is associated with early inflammation, oxidative stress, and endothelial injury in forebrain ischemia–reperfusion rats
33. In vivo real-time measurement of superoxide anion radical with a novel electrochemical sensor
34. Serum glial fibrillary acidic protein as a predictive biomarker of neurological outcome after cardiac arrest
35. The cutoff values of intrathecal interleukin 8 and 6 for predicting the neurological outcome in cardiac arrest victims
36. Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion
37. Safety and Influence of Molecular Hydrogen/Carbon Dioxide Contained Drinking Water on Common Anthropometric and Laboratory Parameters.
38. Urinary trypsin inhibitor suppresses excessive generation of superoxide anion radical, systemic inflammation, oxidative stress, and endothelial injury in endotoxemic rats
39. Comparison of the Predictability of Neurological Outcome by Serum Procalcitonin and Glial Fibrillary Acidic Protein in Postcardiac-Arrest Patients
40. PATIENT-RELATED FACTORS IN THE DECISION TO FORGO LIFE-SUSTAINING TREATMENT IN COMATOSE PATIENTS RESUSCITATED FROM OUT-OF-HOSPITAL CARDIAC ARREST IN JAPAN
41. Global end-diastolic volume, serum osmolarity, and albumin are risk factors for increased extravascular lung water
42. High-Mobility Group Box 1 Protein in CSF of Patients with Subarachnoid Hemorrhage
43. Successful treatment with hydrocortisone for heat stroke with critical illness-related corticosteroid insufficiency: transitional changes in serum cytokine and cortisol concentrations
44. High early phase hemoglobin level is associated with favorable neurological outcome in patients with severe traumatic brain injury
45. Effect of physical restraint on glucose tolerance in cynomolgus monkeys
46. Efficacy and safety of intrapulmonary percussive ventilation superimposed on conventional ventilation in obese patients with compression atelectasis
47. An integrated model of thermodynamic–hemodynamic–pharmacokinetic system and its application on decoupling control of intracranial temperature and pressure in brain hypothermia treatment
48. Nitric Oxide Release from Coronary Vasculature before, during, and following Cardioplegic Arrest
49. Design and Identification of a GPR40 Full Agonist (SCO-267) Possessing a 2-Carbamoylphenyl Piperidine Moiety
50. Activation of Synoviolin Promoter in Rheumatoid Synovial Cells by a Novel Transcription Complex of Interleukin Enhancer Binding Factor 3 and GA Binding Protein α
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