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2. Efficacy and safety of mechanical thrombectomy in acute ischaemic stroke secondary to infective endocarditis

Author

Miró, Jose M., Hernández-Meneses, Marta, Cuervo, Guillermo, Téllez, Adrian, Pericàs, Juan M., Dahl, Anders, García, Delia, Moreno, Asuncion, Ambrosioni, Juan, García de la Mària, Cristina, Cañas, María Alexandra, García-González, Javier, Marco, Francesc, Casals, Climent, Vila, Jordi, Quintana, Eduard, Sandoval, Elena, Falces, Carlos, Pereda, Daniel, Sitges, Marta, Vidal, Barbara, Castella, Manuel, Ortiz, José, Tolosana, José M., Rovira, Irene, Fuster, David, Perissinotti, Andres, Ramírez, Jose, Brunet, Mercè, Soy, Dolors, Castro, Pedro, Llopis, Jaume, Fernández-Hidalgo, Nuria, Escolà-Vergé, Laura, Maisterra, Olga, Fernández, Rubén, Gonzàlez-Alujas, Maria Teresa, Pizzi, María Nazarena, Rello, Pau, Soriano, Toni, Pijuan, Antònia, Sambola, Antonia, Ríos, Remedios, Vigil, Carlota, Roque, Albert, Escrihuela-Vidal, Francesc, Carratalà, Jordi, Grau, Inmaculada, Ardanuy, Carmen, Berbel, Dámaris, Sánchez Salado, Jose Carlos, Alegre, Oriol, Majoral, Alejandro Ruiz, Sbraga, Fabrizio, Blasco, Arnau, Sánchez, Laura Gràcia, Sánchez-Rodríguez, Iván, Pedro-Botet, María Luisa, Sopena, Nieves, Prats-Sánchez, Luis, de Benito, Natividad, Horcajada, Juan Pablo, Roquer, Jaume, Sáez, Carmen, Sanz, Marta, Ramos, Carmen, Ximénez-Carrillo, Álvaro, Vega, Juan, Vilacosta, Isidre, Cardona, Pere, Quesada, Helena, Lara, Blanca, Paipa, Andrés, Nuñez Guillen, Ana, Barranco, Roger, Aja, Lucia, Mora, Paloma, Chirife, Oscar, Aixut, Sonia, Angeles de Miquel, Maria, Martínez-Yelamos, Toni, Molina, Carlos, Rubiera, Marta, Pagola, Jorge, Rodríguez-Luna, David, Boned, Sandra, Muchada, Marian, Tomasello, Alejandro, Ribó, Marc, Piñana, Carlos, Requena, Manuel, Deck, Matías, Garcia-Tornel, Alvaro, Olivé, Marta, Rodriguez, Noelia, Juega, Jesus, Chamorro, Ángel, Amaro, Sergio, Urra, Xabier, Llull, Laura, Renú, Arturo, Rudiloso, Salvatore, Macho, Juan M., Blasco, Jordi, San Roman Manzanera, Luis, López, Antonio, Zarco, Federico, Torné, Ramón, Valero, Ricard, Obach, Víctor, Vera, Víctor, Rodriguez, Alejandro, Vargas, Martha, Laredo, Carlos, Millán, Mònica, Pérez de la Ossa, Natalia, Gomis, Meritxell, Dorado, Laura, Hernández-Pérez, María, Ramos, Anna, Bustamante, Alejandro, Remollo, Sebastià, Castaño, Carlos, Werner, Mariano, Martí-Fàbregas, Joan, Pachón, Anna Ramos, Martínez-Domeño, Alejandro, Camps-Renom, Pol, Lambea, Álvaro, Ezcurra, Garbiñe, Guasch-Jiménez, Marina, Bueno, Rebeca Marín, Pujol, Jordi Branera, Martínez, José Pablo, Dinia, Lavinia, Pellisé, Anna, Ustrell, Xavier, Flores, Alan, Seró, Laia, Serena, Joaquín, Silva, Yolanda, Terceño, Mikel, Bashir, Saima, Murillo, Alan, Krupinski, Jerzy, Huertas, Sonia, Molina, Jessica, Figueras, Georgina, Besora, Sarah, Rodríguez-Campello, Ana, Ois, Ángel, Giralt-Steinhauer, Eva, Cuadrado-Godia, Elisa, Jiménez-Conde, Jordi, Vivas, Elio, Guimaraens, Polo, Cánovas, David, del Carmen Garcia, Maria, Estela, Jordi, Perendreu, Joan, Romero, Nicolas, Correa, Roberto Eduardo, Barrachina, Oriol, Gómez-Choco, Manuel, García, Sonia M., Font Padrós, Maria Àngels, Mengual Chirife, Juan José, Romo, Luis Mena, Palomeras, Ernest, Casado, Virginia, Guanyabens, Nicolau, Álvarez, Marta, Catena, Esther, Camacho Velásquez, José Luis, Purroy, Francisco, Capdevila, Gerard Mauri, Garcia, Cristina, Alhama, Jessica García, Trigo, Irene Bragado, Monedero, Jordi, Perecaula, Mònica, Casanovas, Luis Guillermo, Colom, Carla, Cocho, Dolores, González, Adela Rios, Baiges, Juanjo, Zaragoza, Josep, Escalante, Sonia, Esteve, Patricia, Aragonés, Josep Maria, Saura, Júlia, Soler-Insa, Josep Maria, Mas, Natalia, Diaz, Glòria, Vergés, Margarida, Costa, Xavier, Molina, Liseth, Alemendros, M Cruz, Pérez, Marc, Cabanelas, Ana, Belchi, Olga, Rybyeba, Maria, Barceló, Miquel, Carrión, Dolors, Repullo, Carmen, Sanjurjo, Eduard, Salvat-Plana, Mercè, Roig, Josep, Hidalgo, Verònica, Fagúndez, Olga, Sala, Victòria, Alonso, Anabel, Querol, Marisol, Gorchs, Montse, Jiménez, Xavier, Àngels Mora, Maria, Lapeña, Pau, Olmos, Carmen, Hernández-Fernández, Francisco, Moreno, Asunción, and Chamorro, Angel

Published
2025
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3. Virtual Coiling of Intracranial Aneurysms Based on Dynamic Path Planning

Author

Morales, Hernán G., Larrabide, Ignacio, Kim, Minsuok, Villa-Uriol, Maria-Cruz, Macho, Juan M., Blasco, Jordi, Roman, Luis San, Frangi, Alejandro F., Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Fichtinger, Gabor, editor, Martel, Anne, editor, and Peters, Terry, editor

Published
2011
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6. Outcomes of a Contemporary Cohort of 536 Consecutive Patients With Acute Ischemic Stroke Treated With Endovascular Therapy

Author

Abilleira, Sònia, Cardona, Pere, Ribó, Marc, Millán, Mònica, Obach, Víctor, Roquer, Jaume, Cánovas, David, Martí-Fàbregas, Joan, Rubio, Francisco, Álvarez-Sabín, José, Dávalos, Antoni, Chamorro, Ángel, de Miquel, Maria Angeles, Tomasello, Alejandro, Castaño, Carlos, Macho, Juan M., Ribera, Aida, Gallofré, Miquel, Sanahuja, Jordi, Purroy, Francisco, Serena, Joaquín, Castellanos, Mar, Silva, Yolanda, van Eendenburg, Cecile, Pellisé, Anna, Ustrell, Xavier, Marés, Rafael, Baiges, Juanjo, Garcés, Moisés, Saura, Júlia, Soler Insa, Josep Maria, Aragonés, Josep Maria, Otermín, Pilar, Cocho, Dolores, Palomeras, Ernest, Pérez de la Ossa, Natalia, Gomis, Meritxell, López-Cancio, Elena, Dorado, Laura, Aleu, Aitzíber, García-Bermejo, Pablo, Rubiera, Marta, Santamarina, Esteban, Pagola, Jorge, Molina, Carlos, Coscojuela, Pilar, Quesada, Helena, Cano, Lluis, Aja, Lucia, Mora, Paloma, Cervera, Álvaro, Amaro, Sergio, Urra, Xabier, Blasco-Andaluz, Jordi, San Roman, Luis, Delgado-Mederos, Raquel, Dinia, Lavinia, Carrera-Giraldo, David, Rodríguez-Campello, Ana, Ois, Ángel, Cuadrado-Godia, Elisa, Vivas, Elio, del Carmen Garcia, Maria, Estela, Jordi, Perendreu, Joan, Krupinski, Jerzy, Huertas-Folch, Sonia, Nicolás-Herrerias, M. Carme, Gómez-Choco, Manuel, García, Sonia, and Martínez, Raul

Published
2014
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7. Cerebral Aneurysm Occlusion at 12-Month Follow-Up After Flow-Diverter Treatment: Statistical Modeling for V&V With Real-World Data

Author

Narata, Ana Paula, primary, Obradó, Laura, additional, Moyano, Raquel Kalé, additional, Macho, Juan M., additional, Blasco, Jordi, additional, Rueda, Antonio López, additional, Roman, Luis San, additional, Remollo, Sebastian, additional, Marinelli, Claudia, additional, Cepeda, Rosana, additional, Fernández, Héctor, additional, and Larrabide, Ignacio, additional

Published
2021
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11. Endovascular treatment of intracraneal aneurysm with pipeline embolization device: experience in four centres in Barcelona

Author

Tomasello, Alejandro, primary, Romero, Nicolas, additional, Aixut, Sonia, additional, Miquel, Maria A., additional, Macho, Juan M., additional, Castaño, Carlos, additional, Coscojuela, Pilar, additional, Lemus, Miguel, additional, Aja, Lucia, additional, San Roman, Luis, additional, Blasco, Jordi, additional, and Rovira, Alex, additional

Published
2016
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13. Dynamic estimation of three-dimensional cerebrovascular deformation from rotational angiography

Author

Zhang, Chong, Villa-Uriol, Maria-Cruz, De Craene, Mathieu, Pozo Soler, José Ma. (José María), Macho, Juan M., Frangi Caregnato, Alejandro, and Universitat Pompeu Fabra

Subjects
Diagnòstic per la imatge, Cerebral vasculature, Rotational angiography, Angiografia, Motion estimation, Image registration, Malalties cerebrovasculars
Abstract

Purpose: The objective of this study is to investigate the feasibility of detecting and quantifying 3D cerebrovascular wall motion from a single 3D rotational x-ray angiography (3DRA) acquisition within a clinically acceptable time and computing from the estimated motion field for the further biomechanical modeling of the cerebrovascular wall. Methods: The whole motion cycle of the cerebral vasculature is modeled using a 4D B-spline transformation, which is estimated from a 4D to 2D + t image registration framework. The registration is performed by optimizing a single similarity metric between the entire 2D + t measured projection sequence and the corresponding forward projections of the deformed volume at their exact time instants. The joint use of two acceleration strategies, together with their implementation on graphics processing units, is also proposed so as to reach computation times close to clinical requirements. For further characterizing vessel wall properties, an approximation of the wall thickness changes is obtained through a strain calculation. Results: Evaluation on in silico and in vitro pulsating phantom aneurysms demonstrated an accurate estimation of wall motion curves. In general, the error was below 10% of the maximum pulsation, even in the situation when substantial inhomogeneous intensity pattern was present. Experiments on in vivo data provided realistic aneurysm and vessel wall motion estimates, whereas in regions where motion was neither visible nor anatomically possible, no motion was detected. The use of the acceleration strategies enabled completing the estimation process for one entire cycle in 5-10 min without degrading the overall performance. The strain map extracted from our motion estimation provided a realistic deformation measure of the vessel wall. Conclusions: The authors' technique has demonstrated that it can provide accurate and robust 4D estimates of cerebrovascular wall motion within a clinically acceptable time, although it has to be applied to a larger patient population prior to possible wide application to routine endovascular procedures. In particular, for the first time, this feasibility study has shown that in vivo cerebrovascular motion can be obtained intraprocedurally from a 3DRA acquisition. Results have also shown the potential of performing strain analysis using this imaging modality, thus making possible for the future modeling of biomechanical properties of the vascular wall. This work was partially supported by the CENIT-CDTEAM grant funded by the Spanish Ministry of Science and Innovation, partially generated in the framework of the @neurIST Integrated Project, which is cofinanced by the European Commission (Grant No. IST-027703), and partially supported by the Spanish Ministry of Science and Innovation (Ref. No. TIN2009-14536-C02-01), Plan E, and FEDER.

Published
2011

14. Automated segmentation of cerebral vasculature with aneurysms in 3DRA and TOF-MRA using geodesic active regions: An evaluation study

Author

Bogunovic, Hrvoje, Pozo Soler, José Ma. (José María), Villa-Uriol, Maria-Cruz, Majoie, Charles B. L. M., van den Berg, Rene, Gratama van Andel, Hugo A. F., Macho, Juan M., Blasco, Jordi, San Román, Luis, Frangi Caregnato, Alejandro, ACS - Amsterdam Cardiovascular Sciences, ANS - Amsterdam Neuroscience, Radiology and Nuclear Medicine, and Universitat Pompeu Fabra

Subjects
Quantitative evaluation, Cerebral angiography, Geodesic active regions, Aneurismes cerebrals, Cerebral aneurysms, Vessel segmentation, Angiografia - Tècniques digitals
Abstract

Purpose: To evaluate the suitability of an improved version of an automatic segmentation method based on geodesic active regions (GAR) for segmenting cerebral vasculature with aneurysms from 3D X-ray reconstruc-/ntion angiography (3DRA) and time of °ight magnetic resonance angiography (TOF-MRA) images available in the clinical routine./nMethods: Three aspects of the GAR method have been improved: execution time, robustness to variability in imaging protocols and robustness to variability in image spatial resolutions. The improved GAR was retrospectively evaluated on images from patients containing intracranial aneurysms in the area of the Circle of Willis and imaged with two modalities: 3DRA and TOF-MRA. Images were obtained from two clinical centers, each using di®erent imaging equipment. Evaluation included qualitative and quantitative analyses of/nthe segmentation results on 20 images from 10 patients. The gold standard was built from 660 cross-sections (33 per image) of vessels and aneurysms, manually measured by interventional neuroradiologists. GAR has also been compared to an interactive segmentation method: iso-intensity surface extraction (ISE). In addition, since patients had been imaged with the two modalities, we performed an inter-modality agreement analysis with respect to both the manual measurements and each of the two segmentation methods. Results: Both GAR and ISE di®ered from the gold standard within acceptable limits compared to the imaging resolution. GAR (ISE, respectively) had an average accuracy of 0.20 (0.24) mm for 3DRA and 0.27 (0.30) mm for TOF-MRA, and had a repeatability of 0.05 (0.20) mm. Compared to ISE, GAR had a lower qualitative error in the vessel region and a lower quantitative error in the aneurysm region. The repeatability/nof GAR was superior to manual measurements and ISE. The inter-modality agreement was similar between GAR and the manual measurements. Conclusions: The improved GAR method outperformed ISE qualitatively as well as quantitatively and is suitable for segmenting 3DRA and TOF-MRA images from clinical routine. The authors would like to acknowledge J. Schneiders for providing part of the TOF-MRA imaging data. The authors would like to thank also A. G. Radaelli, M. Nieber, and X. Planes for the help in implementing some of the methods. This work was partially supported by the @neurIST Integrated Project (co-financed by the European Commission through Contract No. IST-027703), the CDTI CENIT-CDTEAM grant funded by the Spanish Ministry of Science and Innovation (MICINN-CDTI), the AGAUR-FI fellowship from Generalitat de Catalunya, and Philips Healthcare (Best, The Netherlands).

Published
2011

18. Automated segmentation of cerebral vasculature with aneurysms in 3DRA and TOF-MRA using geodesic active regions: An evaluation study

Author

Bogunović, Hrvoje, primary, Pozo, José María, additional, Villa-Uriol, María Cruz, additional, Majoie, Charles B. L. M., additional, van den Berg, Rene, additional, Gratama van Andel, Hugo A. F., additional, Macho, Juan M., additional, Blasco, Jordi, additional, San Román, Luis, additional, and Frangi, Alejandro F., additional

Published
2010
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20. A Virtual Coiling Technique for Image-Based Aneurysm Models by Dynamic Path Planning.

Author

Morales, Hernán G., Larrabide, Ignacio, Geers, Arjan J., San Roman, Luis, Blasco, Jordi, Macho, Juan M., and Frangi, Alejandro F.

Subjects
INTRACRANIAL aneurysm diagnosis, ENDOVASCULAR surgery, HEMODYNAMICS, HEURISTIC algorithms, MEDICAL imaging systems, COMPUTATIONAL fluid dynamics, CONTRAST media
Abstract

Computational algorithms modeling the insertion of endovascular devices, such as coil or stents, have gained an increasing interest in recent years. This scientific enthusiasm is due to the potential impact that these techniques have to support clinicians by understanding the intravascular hemodynamics and predicting treatment outcomes. In this work, a virtual coiling technique for treating image-based aneurysm models is proposed. A dynamic path planning was used to mimic the structure and distribution of coils inside aneurysm cavities, and to reach high packing densities, which is desirable by clinicians when treating with coils. Several tests were done to evaluate the performance on idealized and image-based aneurysm models. The proposed technique was validated using clinical information of real coiled aneurysms. The virtual coiling technique reproduces the macroscopic behavior of inserted coils and properly captures the densities, shapes and coil distributions inside aneurysm cavities. A practical application was performed by assessing the local hemodynamic after coiling using computational fluid dynamics (CFD). Wall shear stress and intra-aneurysmal velocities were reduced after coiling. Additionally, CFD simulations show that coils decrease the amount of contrast entering the aneurysm and increase its residence time. [ABSTRACT FROM PUBLISHER]

Published
2013
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21. Abstract 185.

Author

Abilleira, Sònia, Dávalos, Antoni, Chamorro, Ángel, Ribó, Marc, Cardona, Pere, Serena, Joaquín, Krupinski, Jerzy, Martí-Fàbregas, Joan, Roquer, Jaume, Martínez-Yélamos, Antonio, Álvarez-Sabín, José, Cánovas, David, Ustrell, Xavier, Purroy, Francisco, Gómez-Choco, Manuel, Garcés, Moisés, De Miquel, Maria Angels, Tomasello, Alejandro, Macho, Juan M, and Ribera, Aida

Published
2014

22. Abstract 3.

Author

Liebeskind, David S, Sanossian, Nerses, Scalzo, Fabien, Xiang, Bin, Johnson, Mark S, Gupta, Rishi, Jovin, Tudor G, Albers, Gregory W, Lutsep, Helmi L, Smith, Wade S, Killer-Oberpfalzer, Monika, Macho, Juan M, Jansen, Olav, Wahlgren, Nils, and Nogueira, Raul G

Published
2014

23. New insights of the adaptation of flow diverters to the local geometry of vessel in the treatment of intracranial aneurysms.

Author

Jaimejuan A, Estevez-Areco S, Obradó L, Fernandez H, Blasco J, San Román L, Macho JM, Lopes D, Castaño C, Remollo S, and Larrabide I

Abstract

Purpose: It is unclear how flow diverters (FD) and vessels interact in the treatment of intracranial aneurysms. In this study, we examine the local changes in artery and device morphology caused by their mutual interaction., Methods: Pre-treatment 3DRA and post-treatment XperCT or DynaCT images were collected retrospectively from 25 patients. Vessel anatomies and FDs models were obtained by segmenting the corresponding images. Perpendicular cross-sections of vessels and FDs were extracted and described in terms of area, perimeter, and circularity. The geometrical parameters from each vessel were paired point-by-point with those from FDs., Results: FDs cross-sections are typically circular, regardless of the vessel's morphology. The area and perimeter of FD cross-sections were smaller than the vessel in 66.8% of the data; however, they were larger in 30.1%, suggesting that the vessel is radially stretching to accommodate the FD expansion. In 3.1% of the slices, the FD area was larger than the vessel but its perimeter was smaller, indicating a change in the shape of the artery., Conclusions: Expansion of FD is generally restricted by the morphology of the vessel, but the vessel is also able to adapt to the device by changing its shape or stretching.

Published
2025
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