25 results on '"Machado-Pinilla R"'
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2. MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer
3. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells
4. Uso de agentes inductores GSE24.2 para la elaboración de composiciones farmacéuticas para el tratamiento de enfermedades que cursan con senescencia celular
5. Secuencia de nucleótidos y péptidos GSE 24.2 de la disquerina inductores de la actividad telomerasa, procedimiento de obtención, composiciones terapéuticas y sus aplicaciones
6. Secuencias de nucleótidos y péptidos GSE 24.2 de disquerina que puede inducir actividad de la telomerasa, procedimiento para obtener la misma, composiciones terapéuticas y aplicaciones de la misma
7. Acid Ceramidase as a Chemotherapeutic Target to Overcome Resistance to the Antitumoral Effect of Choline Kinase α Inhibition
8. Structure of the SHQ1P-CBF5P complex
9. Structure of Shq1p C-terminal domain
10. 582 Expression of GSE24.2 prevents DNA damage in X-linked dyskeratosis congenita cells
11. 387 An internal domain of dyskerin as a gene therapy approach in X-linked dyskeratosis congenita
12. A combined strategy of serial analysis of gene expression (SAGE) and quantitative PCR (qPCR) to identify four genes that predict outcome in non-small cell lung cancer patients.
13. IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer
14. Identification of drug-sensitive prediction genes by an epigenetic reactivation screen of cisplatin-resistant NSCLC cell lines
15. Reactivation of telomerase activity in telomerase-deficient human cells by the pseudourydine synthase domain of dyskerin
16. Use of global expression profile from non-small cell lung carcinoma (NSCLC) surgical samples to predict response to pemetrexed (P)
17. Acid Ceramidase as a Chemotherapeutic Target to Overcome Resistance to the Antitumoral Effect of Choline Kinase Inhibition
18. MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer.
19. Mechanism of the AAA+ ATPases pontin and reptin in the biogenesis of H/ACA RNPs.
20. Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain.
21. Acid ceramidase as a chemotherapeutic target to overcome resistance to the antitumoral effect of choline kinase α inhibition.
22. The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic.
23. Telomerase deficiency and cancer susceptibility syndromes.
24. Role of CHK2 in cancer development.
25. A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells.
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