323 results on '"Machacek, M."'
Search Results
2. The Infall of the Virgo Elliptical Galaxy M60 toward M87 and the Gaseous Structures Produced by Kelvin-Helmholtz Instabilities
- Author
-
Wood, R. A., Jones, C., Machacek, M. E., Forman, W. R., Bogdan, A., Andrade-Santos, F., Kraft, R. P., Paggi, A., and Roediger, E.
- Subjects
Astrophysics - Astrophysics of Galaxies - Abstract
We present Chandra observations of hot gas structures, characteristic of gas stripping during infall, in the Virgo cluster elliptical galaxy M60 (NGC4649) located $1$ Mpc east of M87. $0.5-2$ keV Chandra X-ray images show a sharp leading edge in the surface brightness $12.4 \pm 0.1$ kpc north and west of the galaxy center in the direction of M87 characteristic of a merger cold front due to M60's motion through the Virgo ICM. We measured a temperature of $1.00 \pm 0.02$ keV for abundance $0.5 Z_\odot$ inside the edge and $1.37^{+0.35}_{-0.19}$ keV for abundance $0.1 Z_\odot$ in the Virgo ICM free stream region. We find that the observed jump in surface brightness yields a density ratio of $6.44^{+1.04}_{-0.67}$ between gas inside the edge and in the cluster free stream region. If the edge is a cold front due solely to the infall of M60 in the direction of M87, we find a pressure ratio of $4.7^{+1.7}_{-1.4}$ and Mach number $1.7 \pm 0.3$. For 1.37 keV Virgo gas we find a total infall velocity for M60 of $1030 \pm 180$ kms$^{-1}$. We calculate the motion in the plane of the sky to be $1012^{+183}_{-192}$ km$^{-1}$ implying an inclination angle $\xi = 11 \pm 3$ degrees. Surface brightness profiles show the presence of a faint diffuse gaseous tail. We identify filamentary, gaseous wing structures caused by the galaxy's motion through the ICM. The structure and dimensions of these wings are consistent with simulations of Kelvin-Helmholtz instabilities as expected if the gas stripping is close to inviscid., Comment: 12 pages, 7 figures, added references, discussion of magnetic fields and other minor text changes to conform to published version, results unchanged
- Published
- 2017
- Full Text
- View/download PDF
3. Merger Hydrodynamics of the Luminous Cluster RXJ1347.5-1145
- Author
-
Kreisch, C. D., Machacek, M. E., Jones, C., and Randall, S. W.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We present an analysis of the complex gas hydrodynamics in the X-ray luminous galaxy cluster RXJ1347.5-1145 caught in the act of merging with a subcluster to its southeast using a combined $186$ ks Chandra exposure, $2.5$ times greater than previous analyses. The primary cluster hosts a sloshing cold front spiral traced by four surface brightness edges $5.^{\prime \prime}85^{+0.04}_{-0.03}$ west, $7.^{\prime \prime}10^{+0.07}_{-0.03}$ southeast, $11.^{\prime \prime}5^{+1.3}_{-1.2}$ east, and $16.^{\prime \prime}7^{+0.3}_{-0.5}$ northeast from the primary central dominant galaxy, suggesting the merger is in the plane of the sky. We measure temperature and density ratios across these edges, confirming they are sloshing cold fronts. We observe the eastern edge of the subcluster infall shock, confirming the observed subcluster is traveling from the southwest to the northeast in a clockwise orbit. We measure a shock density contrast of $1.38^{+0.16}_{-0.15}$ and infer a Mach number $1.25\pm0.08$ and a shock velocity of $2810^{+210}_{-240}$ km s$^{-1}$. Temperature and entropy maps show cool, low entropy gas trailing the subcluster in a southwestern tail, consistent with core shredding. Simulations suggest a perturber in the plane of the sky on a clockwise orbit would produce a sloshing spiral winding counterclockwise, opposite to that observed. The most compelling solution to this discrepancy is that the observed southeastern subcluster is on its first passage, shock heating gas during its clockwise infall, while the main cluster's clockwise cold front spiral formed from earlier encounters with a second perturber orbiting counterclockwise., Comment: 17 pages, 14 figures
- Published
- 2016
- Full Text
- View/download PDF
4. Self-excited Vibrations of a Bridge Deck with Single and Double Wind Barriers
- Author
-
Buljac, A., Kozmar, H., Macháček, M., Pospíšil, S., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Ricciardelli, Francesco, editor, and Avossa, Alberto Maria, editor
- Published
- 2019
- Full Text
- View/download PDF
5. Stripped elliptical galaxies as probes of ICM physics: II. Stirred, but mixed? Viscous and inviscid gas stripping of the Virgo elliptical M89
- Author
-
Roediger, E., Kraft, R. P., Nulsen, P. E. J., Forman, W. R., Machacek, M., Randall, S., Jones, C., Churazov, E., and Kokotanekova, R.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Elliptical galaxies moving through the intra-cluster medium (ICM) are progressively stripped of their gaseous atmospheres. X-ray observations reveal the structure of galactic tails, wakes, and the interface between the galactic gas and the ICM. This fine-structure depends on dynamic conditions (galaxy potential, initial gas contents, orbit in the host cluster), orbital stage (early infall, pre-/post-pericenter passage), as well as on the still ill-constrained ICM plasma properties (thermal conductivity, viscosity, magnetic field structure). Paper I describes flow patterns and stages of inviscid gas stripping. Here we study the effect of a Spitzer-like temperature dependent viscosity corresponding to Reynolds numbers, Re, of 50 to 5000 with respect to the ICM flow around the remnant atmosphere. Global flow patterns are independent of viscosity in this Reynolds number range. Viscosity influences two aspects: In inviscid stripping, Kelvin-Helmholtz instabilities (KHIs) at the sides of the remnant atmosphere lead to observable horns or wings. Increasing viscosity suppresses KHIs of increasing length scale, and thus observable horns and wings. Furthermore, in inviscid stripping, stripped galactic gas can mix with the ambient ICM in the galaxy's wake. This mixing is suppressed increasingly with increasing viscosity, such that viscously stripped galaxies have long X-ray bright, cool wakes. We provide mock X-ray images for different stripping stages and conditions. While these qualitative results are generic, we tailor our simulations to the Virgo galaxy M89 (NGC 4552), where Re~ 50 corresponds to a viscosity of 10% of the Spitzer level. Paper III compares new deep Chandra and archival XMM-Newton data to our simulations., Comment: ApJ in press. 16 pages, 16 figures. Text clarified, conclusions unchanged
- Published
- 2014
- Full Text
- View/download PDF
6. Stripped elliptical galaxies as probes of ICM physics: I. Tails, wakes, and flow patterns in and around stripped ellipticals
- Author
-
Roediger, E., Kraft, R. P., Nulsen, P. E. J., Forman, W. R., Machacek, M., Randall, S., Jones, C., Churazov, E., and Kokotanekova, R.
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Elliptical cluster galaxies are progressively stripped of their atmospheres due to their motion through the intra-cluster medium (ICM). Deep X-ray observations reveal the fine-structure of the galaxy's remnant atmosphere and its gas tail and wake. This fine-structure depends on dynamic conditions (galaxy potential, initial gas contents, orbit through the host cluster), orbital stage (early infall, pre-/post-pericenter passage), and ICM plasma properties (thermal conductivity, viscosity, magnetic field structure). We aim to disentangle dynamic and plasma effects in order to use stripped ellipticals as probes of ICM plasma properties. This first paper of a series investigates the hydrodynamics of progressive gas stripping by means of inviscid hydrodynamical simulations. We distinguish a long-lasting initial relaxation phase and a quasi-steady stripping phase. During quasi-steady stripping, the ICM flow around the remnant atmosphere resembles the flow around solid bodies, including a `deadwater' region in the near wake. Gas is stripped from the remnant atmosphere predominantly at its sides via Kelvin-Helmholtz instabilities. The downstream atmosphere is largely shielded from the ICM wind and thus shaped into a tail. Observationally, both, this `remnant tail' and the stripped gas in the wake can appear as a `tail', but only in the wake can galactic gas mix with the ambient ICM. While the qualitative results are generic, the simulations presented here are tailored to the Virgo elliptical galaxy M89 (NGC 4552) for the most direct comparison to observations. Papers II and III of this series describe the effect of viscosity and compare to Chandra and XMM-Newton observations, respectively., Comment: ApJ, in press. 19 pages, 13 figures. Clarifications added, text restructured. Conclusions unchanged
- Published
- 2014
- Full Text
- View/download PDF
7. Irregular sloshing cold fronts in the nearby merging groups NGC 7618 and UGC 12491: evidence for Kelvin-Helmholtz instabilities
- Author
-
Roediger, E., Kraft, R. P., Machacek, M. E., Forman, W. R., Nulsen, P. E. J., Jones, C., and Murray, S. S.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We present results from two \sim30 ks Chandra observations of the hot atmospheres of the merging galaxy groups centered around NGC 7618 and UGC 12491. Our images show the presence of arc-like sloshing cold fronts wrapped around each group center and \sim100 kpc long spiral tails in both groups. Most interestingly, the cold fronts are highly distorted in both groups, exhibiting 'wings' along the fronts. These features resemble the structures predicted from non-viscous hydrodynamic simulations of gas sloshing, where Kelvin-Helmholtz instabilities (KHIs) distort the cold fronts. This is in contrast to the structure seen in many other sloshing and merger cold fronts, which are smooth and featureless at the current observational resolution. Both magnetic fields and viscosity have been invoked to explain the absence of KHIs in these smooth cold fronts, but the NGC 7618/UGC 12491 pair are two in a growing number of both sloshing and merger cold fronts that appear distorted. Magnetic fields and/or viscosity may be able to suppress the growth of KHIs at the cold fronts in some clusters and groups, but clearly not in all. We propose that the presence or absence of KHI-distortions in cold fronts can be used as a measure of the effective viscosity and/or magnetic field strengths in the ICM., Comment: ApJ, accepted. Uses emulateapj style
- Published
- 2012
- Full Text
- View/download PDF
8. Gas sloshing, cold fronts, Kelvin-Helmholtz instabilities and the merger history of the cluster of galaxies Abell 496
- Author
-
Roediger, E., Lovisari, L., Dupke, R., Ghizzardi, S., Brüggen, M., Kraft, R. P., and Machacek, M. E.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We investigate the origin and nature of the multiple sloshing cold fronts in the core of Abell 496 by direct comparison between observations and dedicated hydrodynamical simulations. Our simulations model a minor merger with a 4{\times}10^13M{\circ} subcluster crossing A496 from the south-west to the north-north-east, passing the cluster core in the south-east at a pericentre distance 100 to a few 100 kpc about 0.6 to 0.8 Gyr ago. The gas sloshing triggered by the merger can reproduce almost all observed features, e.g. the characteristic spiral-like brightness residual distribution in the cluster centre and its asymmetry out to 500 kpc, also the positions of and contrasts across the cold fronts. If the subcluster passes close (100 kpc) to the cluster core, the resulting shear flows are strong enough to trigger Kelvin-Helmholtz instabilities that in projection resemble the peculiar kinks in the cold fronts of Abell 496. Finally, we show that sloshing does not lead to a significant modification of the global ICM profiles but a mild oscillation around the initial profiles., Comment: MNRAS, accepted, 19 pages
- Published
- 2011
- Full Text
- View/download PDF
9. Deep Chandra Observations of Edges and Bubbles in the NGC 5846 Galaxy Group
- Author
-
Machacek, M. E., Jerius, D., Kraft, R. P., Forman, W. R., Jones, C., Randall, S., Giancintucci, S., and Sun, M.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We use a combined 120 ks Chandra exposure to analyze X-ray edges produced by non-hydrostatic gas motions (sloshing) from galaxy collisions, and cavities formed by AGN activity. Evidence for gas sloshing is seen in the spiral morphology and multiple cold front edges in NGC 5846's X-ray surface brightness distribution, while lack of spiral structure in the temperature map suggests the perturbing interaction was not in the plane of the sky. Density and spectral modeling across the edges indicate the relative motion of gas in the cold fronts is at most transonic. Evidence for AGN activity is seen in two inner bubbles at 0.6 kpc, filled with 5 GHz and 1.5 GHz radio plasma and coincident with Halpha emission, and in a ghost bubble at 5.2 kpc west of NGC 5846's nucleus. The outburst energy and ages for the inner (ghost) bubbles are ~10^{55} ergs and ~2 Myr (~ 5 x 10^{55} ergs and 12 Myr), respectively, implying an AGN duty cycle of 10 Myr. The inner bubble rims are threaded with 9 knots, whose total 0.5-2 keV X-ray luminosity is 0.3 x10^{40} ergs, a factor ~2-3 less than that of the surrounding rims, and 0.7 keV mean temperature is indistinguishable from that of the rims. We suggest that the knots may be transient clouds heated by the recent passage of a shock from the last AGN outburst. We also observe gas stripping from a cE galaxy, NGC 5846A, in a 0.5 kpc long (~10^5 Msolar) hot gas tail, as it falls towards NGC 5846., Comment: 18 pages, 26 figures, ApJ, in press
- Published
- 2011
- Full Text
- View/download PDF
10. The Mysterious Merger of NGC6868 and NGC6861 in the Telescopium Group
- Author
-
Machacek, M. E., O'Sullivan, E., Randall, S. W., Jones, C., and Forman, W. R.
- Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
We use Chandra X-ray observations of the hot gas in and around NGC6868 and NGC6861 in the Telescopium galaxy group (AS0851) to probe the interaction history between these galaxies. Mean surface brightness profiles for NGC6868 and NGC6861 are each well described by double beta-models, suggesting that they are each the dominant galaxy in a galaxy subgroup about to merge. Surface brightness and temperature maps of the brightest group galaxy NGC6868 show a cold front edge ~23 kpc to the north, and a cool 0.62 keV spiral-shaped tail to the south. Analysis of the temperature and density across the cold front constrains the relative motion between NGC6868 and the ambient group gas to be at most transonic; while the spiral morphology of the tail strongly suggests that the cold front edge and tail are the result of gas sloshing due to the subgroup merger. The cooler central region of NGC6861 is surrounded by a sheath of hot gas to the east and hot, bifurcated tails of X-ray emission to the west and northwest. We discuss supersonic infall of the NGC6861 subroup, sloshing from the NGC6868 and NGC6861 subgroup merger, and AGN heating as possible explanations for these features, and discuss possible scenarios that may contribute to the order of magnitude discrepancy between the Margorrian and black hole mass - sigma predictions for its central black hole., Comment: 17 pages, 23 figures, submitted to ApJ
- Published
- 2010
- Full Text
- View/download PDF
11. A Chandra Study of the NGC 7618/UGC 12491 Major Group Merger at Apogee: Multiple Cold Fronts, Boxy Wings, Filaments, and Arc-shaped Slingshot Tails
- Author
-
Machacek, M. E., primary, Jones, C., additional, Kraft, R. P., additional, Forman, W. R., additional, Roediger, E., additional, Sheardown, A., additional, and Wan, J. T., additional
- Published
- 2023
- Full Text
- View/download PDF
12. A Multiwavelength View of Star Formation in Interacting Galaxies in the Pavo Group
- Author
-
Machacek, M., Ashby, M. L. N., Jones, C., Forman, W. R., and Bastian, N.
- Subjects
Astrophysics - Abstract
We combine Spitzer IRAC mid-infrared (MIR) and Chandra X-ray observations of the dominant galaxies NGC6872 and NGC6876 in the Pavo group with archival optical and HI data to study interaction-induced star formation. In spiral galaxy NGC6872, 8.0 and 5.8 micron nonstellar emission having colors consistent with polycyclic aromatic hydrocarbons (PAHs) is concentrated in clumps in three regions: in a 5 kpc radius outer ring about the center of the spiral galaxy, in a bridge of emission connecting NGC6872's northern spiral arm to IC4970, and along the full extent of NGC6872's tidal arms. PAH emission is correlated with young star clusters and dense HI regions. We find no strong differences in the MIR colors of star-forming regions in the spiral galaxy NGC6872 as a function of position relative to the tidally interacting companion galaxy IC4970. We find 11 very luminous X-ray sources (>~ (0.5 - 5) x 10^{39} ergs/s) clustered to the southwest in NGC6872, near bright star-forming regions. In NGC6872's tidal features, young star clusters form at the boundaries of diffuse X-ray gas, suggesting that stars form as gas stripped by the interactions cools. The nucleus of NGC6872 is a weak X-ray point source (0.5-8 keV luminosity of 8.5 x 10^{39} ergs/s), but there is little evidence in the inner 1 kpc of NGC6872 for PAH emission from recent star formation or nuclear activity. However, a 4 kpc `stream', leading from the outer ring of NGC6872 to the nucleus, may signal transport of interstellar matter into NGC6872's nuclear region. Nonstellar emission, consistent with PAH emission, is also found in the central region of elliptical galaxy NGC6877, companion to dominant Pavo group elliptical NGC6876. However, in the central region of NGC6876, the dust emission is more likely due to silicate emission from old AGB stars., Comment: 17 pages, 24 figures, ApJ, accepted
- Published
- 2008
- Full Text
- View/download PDF
13. Chandra's View of the Ram Pressure Stripped Galaxy M86
- Author
-
Randall, S., Nulsen, P., Forman, W. R., Jones, C., Machacek, M., Murray, S. S., and Maughan, B.
- Subjects
Astrophysics - Abstract
We present results from a mosaic of nine Chandra observations of M86 and the surrounding field. We detect three main diffuse components: the Virgo ICM at ~2.4 keV, the extended halo of M86 at ~1.2 keV, and the cooler central and stripped gas of M86 at ~0.8 keV. The most striking feature is a long tail of emission, which consists of a plume ~ 4' north of M86 and two main extensions emanating from the plume. Based on the morphology and temperature structure of the tail, we conclude that it is formed by ram pressure stripping of M86 as it falls into the Virgo cluster and interacts with the Virgo ICM, in agreement with earlier work. The tail is 150 kpc in projection, and a simple estimate gives a lower limit on the true length of the tail of 380 kpc, making this the longest ram pressure stripped tail presently known. The total gas mass in the plume (7x10^8 M_sun) and tail (1x10^9 M_sun) is about three times that in the core of M86, which supports the scenario where most of the gas was stripped rapidly and recently. The projected position of the plume can be understood if M86 has an aspherical potential, as suggested by optical isophotes. Ram pressure stripping from an aspherical potential can also explain the split "double tails" seen in M86 and in other Virgo cluster galaxies in the field. The large line-of-sight velocity of M86 (1550 km/s with respect to M87), its position relative to the Virgo cluster, and the orientation of the tail tightly constrain its orbital parameters. The data are inconsistent with a radial orbit, and imply inner and outer turning radii of r_i ~ 300 kpc and r_o > 8.8 Mpc, indicating that M86 is, at best, only weakly bound to the Virgo cluster., Comment: 24 pages, 15 figures, submitted to ApJ. Version with high-resolution figures available at http://hea-www.harvard.edu/~srandall/M86/
- Published
- 2008
- Full Text
- View/download PDF
14. The Active Nucleus of IC4970: A Nearby Example of Merger-Induced Cold-Gas Accretion
- Author
-
Machacek, M. E., Kraft, R. P., Ashby, M. L. N., Evans, D. A., Jones, C., and Forman, W. R.
- Subjects
Astrophysics - Abstract
We present results from Chandra X-ray and Spitzer mid-infrared observations of the interacting galaxy pair NGC6872/IC4970 in the Pavo galaxy group and show that the smaller companion galaxy IC4970 hosts a highly obscured active galactic nucleus (AGN). The 0.5-10 keV X-ray luminosity of the nucleus is variable, increasing by a factor 2.9 to 1.7 x 10^{42} erg/s (bright state) on ~100 ks timescales. The X-ray spectrum of the is heavily absorbed (N_H = 3 x 10^{23} cm^{-2}) for power law models with Gamma = 1.5-2.0 and shows a clear 6.4 keV Fe Kalpha line with equivalent width of 144-195 eV. Limits on the diffuse emission in IC4970 from Chandra X-ray data suggest that the available power from Bondi accretion of hot interstellar gas may be an order of magnitude too small to power the AGN. Spitzer images show that 8 micron nonstellar emission is concentrated in the central 1 kpc of IC4970, consistent with high obscuration in this region. The mid-infrared colors of the nucleus are consistent with those expected for a highly obscured AGN. Taken together these data suggest that the nucleus of IC4970 is a Seyfert 2, triggered and fueled by cold material supplied to the central supermassive black hole as a result of the off-axis collision of IC4970 with the cold-gas rich spiral galaxy NGC6872., Comment: 10 pages, 9 figures, submitted to ApJ, MIR flux conversion error corrected in Table 4, MIR colors and paper text unchanged
- Published
- 2007
- Full Text
- View/download PDF
15. X-ray Constraints on Galaxy-Gas-Jet Interactions in the Dumbbell Galaxies NGC4782 and NGC4783 in the LGG316 Group
- Author
-
Machacek, M. E., Kraft, R. P., Jones, C., Forman, W. R., and Hardcastle, M. J.
- Subjects
Astrophysics - Abstract
We present results from a 49.3 ks Chandra X-ray observation of the strongly interacting dumbbell galaxies NGC4782(3C278) and NGC4783 that constrain the kinematics of the interaction and models for bending the radio jets associated with NGC4782. The galaxies are embedded in an approximately spherical distribution of group gas, centered on NGC4782,that is nearly isothermal with mean kT ~ 1.4+/- 0.4 keV. The X-ray morphology suggests that NGC4783 is infalling into a single, massive galaxy group (LGG316) with NGC4782 nearly at rest at the center of the group potential.NGC4783 shows a sharp X-ray surface brightness edge (cold front) to the east and a ~15 kpc ram-pressure-stripped tail to the west. Analysis of this cold front indicates NGC4783 is moving east with a total velocity ~870+270-400 km/s (Mach ~1.4+0.5-0.7) at an inclination angle ~46 deg.(>33 deg.)towards us with respect to theplane of the sky. A ~45Myr old X-ray cavity, with enthalpy of 4.4 x 10^{57}ergs, coincides with the eastern radio lobe of 3C278. X-ray knots are found on both the radio jet and counter-jet, coincident with peaks in the radio emission. Assuming a light, mildly relativistic jet in 3C278, ram pressure velocities of 100-200 km/s impacting the eastern jet and ~170 km/s acting on the western radio lobe are sufficient to produce their observed bending. These velocities may be caused by bulk motions established in the IGM by the high velocity interaction between the galaxies, by the motion of NGC4782 relative to the IGM, or both., Comment: 18 pages, 15 figures, ApJ accepted, revisions to conform to published version, new figures,revised tables, improved discussion of backgrounds and uncertainties
- Published
- 2006
- Full Text
- View/download PDF
16. Chandra Observations of Nuclear Outflows in the Elliptical Galaxy NGC4552 in the Virgo Cluster
- Author
-
Machacek, M., Nulsen, P. E. J., Jones, C., and Forman, W. R.
- Subjects
Astrophysics - Abstract
We use a 54.4 ks Chandra observation to study nuclear outflow activity in NGC4552 (M89), an elliptical galaxy in the Virgo Cluster. Chandra images in the 0.5-2 keV band show two ring-like features ~1.7 kpc in diameter in the core of NGC4552, as reported previously by Filho et al. We use spherically symmetric point explosion shock models to argue that the shape of the surface brightness profile across the rims of the rings and the temperature of hot gas in the rings are consistent with a Mach 1.7 shock carrying mean mechanical power L_shock ~ 3 x 10^{41} ergs/s produced by a ~1.4 x 10^{55} ergs nuclear outburst \~1 - 2 Myr ago. We find the gas temperature in the central ~100 pc of the galaxy to be 1.0 +/- 0.2 keV, hotter than elsewhere in the galaxy, suggesting that we may be observing directly the reheating of the galaxy ISM by the outburst., Comment: second part (sec. 4) of astroph/0508588v1 with expanded intro and discussion; 16 pages, 8 figs., ApJ, submitted
- Published
- 2006
- Full Text
- View/download PDF
17. Chandra Observations of Gas Stripping in the Elliptical Galaxy NGC 4552 in the Virgo Cluster
- Author
-
Machacek, M., Jones, C., Forman, W. R., and Nulsen, P. E. J.
- Subjects
Astrophysics - Abstract
We use a 54.4 ks Chandra observation to study ram-pressure stripping in NGC4552 (M89), an elliptical galaxy in the Virgo Cluster. Chandra images in the 0.5-2 keV band show a sharp leading edge in the surface brightness 3.1 kpc north of the galaxy center, a cool (kT =0.51^{+0.09}_{-0.06} keV) tail with mean density n_e ~5.4 +/- 1.7 x 10^{-3} cm^{-3} extending ~10 kpc to the south of the galaxy, and two 3-4 kpc horns of emission extending southward away from the leading edge. These are all features characteristic of supersonic ram-pressure stripping of galaxy gas, due to NGC4552's motion through the surrounding Virgo ICM. Fitting the surface brightness profile and spectra across the leading edge, we find the galaxy gas inside the edge is cooler (kT = 0.43^{+0.03}_{-0.02} keV) and denser (n_e ~ 0.010 cm^{-3}) than the surrounding Virgo ICM (kT = 2.2^{+0.7}_{-0.4} keV and n_e = 3.0 +/- 0.3 x 10^{-4} cm^{-3}). The resulting pressure ratio between the free-streaming ICM and cluster gas at the stagnation point is ~7.6^{+3.4}_{-2.0} for galaxy gas metallicities of 0.5^{+0.5}_{-0.3} Zsolar, which suggests that NGC4552 is moving supersonically through the cluster with a velocity v ~ 1680^{+390}_{-220} km/s (Mach 2.2^{+0.5}_{-0.3}) at an angle xi ~ 35 +/- 7 degrees towards us with respect to the plane of the sky., Comment: 31 pages, 12 figures, ApJ, in press; paper split into 2 parts, Paper I(sec 1-3) here, added figs and discussion to conform to published version; Paper II (sec. 4) in astro-ph/0604406
- Published
- 2005
- Full Text
- View/download PDF
18. XMM-Newton Observation of an X-ray Trail Between the Spiral Galaxy NGC6872 and the Central Elliptical NGC6876 in the Pavo Group
- Author
-
Machacek, M., Nulsen, P., Stirbat, L., Jones, C., and Forman, W.
- Subjects
Astrophysics - Abstract
We present XMM-Newton observations of a trail of enhanced X-rayemission extending along the 8'.7 X 4' region between the spiral NGC6872 and the dominant elliptical NGC6876 in the Pavo Group,the first known X-ray trail associated with a spiral galaxy in a poor galaxy group and, with projected length of 90 kpc, one of the longest X-ray trails observed in any system. The X-ray surface brightness in the trail region is roughly constant beyond ~20 kpc of NGC6876 in the direction of NGC6872. The trail is hotter (~ 1 keV) than the undisturbed Pavo IGM (~0.5 keV) and has low metal abundances (0.2 Zsolar). The 0.5-2 keV luminosity of the trail, measured using a 67 X 90 kpc rectangular region, is 6.6 X 10^{40} erg/s. We compare the properties of gas in the trail to the spectral properties of gas in the spiral NGC6872 and in the elliptical NGC6876 to constrain its origin. We suggest that the X-ray trail is either IGM gas gravitationally focused into a Bondi-Hoyle wake, a thermal mixture of ~64% Pavo IGM gas with ~36% galaxy gas that has been removed from the spiral NGC6872 by turbulent viscous stripping, or both, due to the spiral's supersonic motion at angle xi ~ 40 degrees with respect to the plane of the sky, past the Pavo group center (NGC6876) through the densest region of the Pavo IGM. Assuming xi = 40 degrees and a filling factor eta in a cylindrical volume with radius 33 kpc and projected length 90 kpc, the mean electron density and total hot gas mass in the trail is 9.5 X 10^{-4}*eta^{-1/2} cm^{-3} and 1.1 X 10^{10}*eta^{1/2} Msolar, respectively., Comment: typos corrected in Eq. 7 & 8, figures and discussion unchanged, 39 pages, 11 postscript figures, submitted to ApJ
- Published
- 2004
- Full Text
- View/download PDF
19. Infall of the Elliptical Galaxy NGC 1404 into the Fornax Cluster
- Author
-
Machacek, M., Dosaj, A., Forman, W., Jones, C., Markevitch, M., Vikhlinin, A., Warmflash, A., and Kraft, R.
- Subjects
Astrophysics - Abstract
We use three Chandra observations, totalling 134.3 ks, to constrain the dynamical motion of NGC1404 falling towards the dominant elliptical NGC1399 through the Fornax ICM. NGC1404's surface brightness profile shows a sharp edge \~8 kpc from its center in the direction of NGC 1399, characteristic of jump-like temperature and density discontinuities from ram-pressure stripping of the galaxy gas. We find the temperature of the galaxy gas inside the edge is \~2.8 times cooler (kT=0.55^{+0.01}_{-0.02} keV; abundance A = 0.73^{+0.65}_{-0.16} solar) than the cluster gas (kT,A = 1.53^{+0.10}_{-0.13} keV, 0.42^{+0.2}_{-0.13} solar). We use the shape of the surface brightness profile to fit the edge position, power law index of the density distribution inside the edge, and density discontinuity at the edge. The electron density inside the edge (3.9-4.3 x 10^{-3} cm^{-3}) depends strongly on the gas abundance; while the density of the ICM (7-8 x10^{-4} cm^{-3}) depends strongly on the assumed relative distance between NGC1404 and NGC1399. The pressure jump (1.7-2.1) across the edge and the cluster free-stream region implies a Mach number 0.83-1.03 and velocity 531-657 km/s for NGC1404 relative to the ICM. The inclination angle of the motion inferred using the relative radial velocity between NGC1404 and NGC1399 as representative of that between NGC1404 and the ICM, is uncomfortably large (>40 deg.) given the sharpness of the edge, suggesting either a non-zero impact parameter between the galaxies, or that NGC1399 is moving radially with respect to the cluster ICM., Comment: 20 pages, 7 postscript figures, submitted to ApJ
- Published
- 2004
- Full Text
- View/download PDF
20. Chandra Observations of Galaxy Cluster Abell 2218
- Author
-
Machacek, M. E., Bautz, M. W., Canizares, C. R., and Garmire, G. P.
- Subjects
Astrophysics - Abstract
We present results from two observations (combined exposure of ~17 ks) of galaxy cluster A2218 using the Advanced CCD Imaging Spectrometer on board the Chandra X-ray Observatory that were taken on October 19, 1999. Using a Raymond-Smith single temperature plasma model corrected for galactic absorption we find a mean cluster temperature of kT = 6.9+/-0.5 keV, metallicity of 0.20+/-0.13 (errors are 90 % CL) and rest-frame luminosity in the 2-10 keV energy band of 6.2x10^{44} erg/s in a LambdaCDM cosmology with H_0=65 km/s/Mpc. The brightness distribution within 4'.2 of the cluster center is well fit by a simple spherical beta model with core radius 66".4 and beta = 0.705 . High resolution Chandra data of the inner 2' of the cluster show the x-ray brightness centroid displaced ~22" from the dominant cD galaxy and the presence of azimuthally asymmetric temperature variations along the direction of the cluster mass elongation. X-ray and weak lensing mass estimates are in good agreement for the outer parts (r > 200h^{-1}) of the cluster; however, in the core the observed temperature distribution cannot reconcile the x-ray and strong lensing mass estimates in any model in which the intracluster gas is in thermal hydrostatic equilibrium. Our x-ray data are consistent with a scenario in which recent merger activity in A2218 has produced both significant non-thermal pressure in the core and substructure along the line of sight; each of these phenomena probably contributes to the difference between lensing and x-ray core mass estimates., Comment: 33 pages, 6 figures, uses AASTeX 5.02, ApJ submitted
- Published
- 2001
- Full Text
- View/download PDF
21. Hydrodynamical simulations of the Lyman-Alpha forest: data comparisons
- Author
-
Meiksin, A., Bryan, G., and Machacek, M.
- Subjects
Astrophysics - Abstract
Numerical hydrodynamical simulations are used to predict the expected absorption properties of the Lyman-Alpha forest for a variety of Cold Dark Matter dominated cosmological scenarios: CHDM, OCDM, LCDM, SCDM, and tCDM. Synthetic spectra are constructed duplicating the resolution, signal-to-noise ratio, and wavelength coverage of several published high resolution spectra, and their statistical properties compared on the basis of the flux distribution of the spectra, the distribution of coefficients in a wavelet decomposition of the spectra, and the distributions of absorption line profile parameters. Agreement between the measured and predicted cumulative distributions is found at the few to several percent level. The best-fitting models to the flux distribution correspond to normalizations on the scale of the cosmological Jeans length of 1.3 < sigma_J < 1.7 at z=3. No single model provides an acceptable match to all the distributions. Larger median Doppler parameters are found in the measured spectra than predicted by all but the lowest normalization models (CHDM and tCDM), which provide poor fits to the flux distributions. The discrepancy in Doppler parameters is particularly large for absorption systems optically thin at the Lyman-Alpha line-centre. This may indicate the need to introduce additional energy injection throughout the IGM, as may be provided by late HeII reionization (z_HeII~3.5) or supernovae-driven winds from young galaxies. The models require a hydrogen ionization rate at redshifts 1.7
3.5 than predicted from current QSO counts., Comment: Major Revision. 29 pages, 26 figures. Accepted for publication in MNRAS - Published
- 2001
- Full Text
- View/download PDF
22. Hydrodynamical Simulations of the Lyman Alpha Forest: Model Comparisons
- Author
-
Machacek, M. E., Bryan, G. L., Meiksin, A., Anninos, P., Thayer, D., Norman, M. L., and Zhang, Y.
- Subjects
Astrophysics - Abstract
We investigate the properties of the Lyman alpha forest as predicted by numerical simulations for a range of currently viable cosmological models. This is done in order to understand the dependencies of the forest on cosmological parameters. Focusing on the redshift range from two to four, we show that: (1) most of the evolution in the distributions of optical depth, flux and column density can be understood by simple scaling relations, (2) the shape of optical depth distribution is a sensitive probe of the amplitude of density fluctuations on scales of a few hundred kpc, (3) the mean of the b distribution (a measure of the width of the absorption lines) is also very sensitive to fluctuations on these scales, and decreases as they increase. We perform a preliminary comparison to observations, where available. A number of other properties are also examined, including the evolution in the number of lines, the two-point flux distribution and the HeII opacity., Comment: 37 pages, 21 figures, submitted to ApJ
- Published
- 1999
- Full Text
- View/download PDF
23. The Lyman Alpha Forest in Hierarchical Cosmologies
- Author
-
Machacek, M., Bryan, G., Anninos, P., Meiksin, A., Norman, M. L., and Zhang, Y.
- Subjects
Astrophysics - Abstract
The comparison of quasar absorption spectra with numerically simulated spectra from hierarchical cosmological models of structure formation promises to be a valuable tool to discriminate among these models. We present simulation results for the column density, Doppler b parameter, and optical depth probability distributions for five popular cosmological models., Comment: 4 pages, 3 figures, uses aipproc.sty, to appear in the Proceedings of the 9th Annual October Astrophysics Conference in Maryland, "After the Dark Ages: When Galaxies Were Young (the Universe at 2
- Published
- 1999
- Full Text
- View/download PDF
24. Two Distinct Actin Networks Drive the Protrusion of Migrating Cells
- Author
-
Ponti, A., Machacek, M., Gupton, S. L., Waterman-Storer, C. M., and Danuser, G.
- Published
- 2004
25. First-in-man dose escalation and pharmacokinetic study of CAP7.1, a novel prodrug of etoposide, in adults with refractory solid tumours
- Author
-
Keilholz, U., Rohde, L., Mehlitz, P., Knoedler, M., Schmittel, A., Kümmerlen, V., Klinghammer, K., Treasure, P., Lassus, M., Steventon, G., Machacek, M., and Utku, N.
- Published
- 2017
- Full Text
- View/download PDF
26. Dynamics of the Hot Intracluster Medium
- Author
-
Jones, C., Forman, W., Vikhlinin, A., Markevitch, M., Machacek, M., Churazov, E., Beig, R., editor, Beiglböck, W., editor, Domcke, W., editor, Englert, B.-G., editor, Frisch, U., editor, Hänggi, P., editor, Hasinger, G., editor, Hepp, K., editor, Hillebrandt, W., editor, Imboden, D., editor, Jaffe, R. L., editor, Lipowsky, R., editor, Löhneysen, H. v., editor, Ojima, I., editor, Sornette, D., editor, Theisen, S., editor, Weise, W., editor, Wess, J., editor, Zittartz, J., editor, Plionis, Manolis, editor, Hughes, David, editor, and López-Cruz, Omar, editor
- Published
- 2008
- Full Text
- View/download PDF
27. Quantitative Flow Visualization for Large Scale Wind Tunnels
- Author
-
Bömmels, R., Machacek, M., Landolt, A., Rösgen, T., Pfeiffer, Friedrich, editor, Wriggers, Peter, editor, McCallen, Rose, editor, Browand, Fred, editor, and Ross, James, editor
- Published
- 2004
- Full Text
- View/download PDF
28. Peripherally Crowded Cationic Phthalocyanines as Efficient Photosensitizers for Photodynamic Therapy
- Author
-
Halaskova M., Rahali A., Almeida-Marrero V., Machacek M., Kucera R., Jamoussi B., Torres T., Novakova V., De La Escosura A., Zimcik P.
- Published
- 2021
29. Subphthalocyanines as Efficient Photosensitizers with Nanomolar Photodynamic Activity against Cancer Cells
- Author
-
Demuth J., Gallego L., Kozlikova M., Machacek M., Kucera R., Torres, Tomás, Martinez-Diaz M.V., Novakova V., Demuth J., Gallego L., Kozlikova M., Machacek M., Kucera R., Torres, Tomás, Martinez-Diaz M.V., and Novakova V.
- Published
- 2021
30. Peripherally Crowded Cationic Phthalocyanines as Efficient Photosensitizers for Photodynamic Therapy
- Author
-
Halaskova M., Rahali A., Almeida-Marrero V., Machacek M., Kucera R., Jamoussi B., Torres, Tomás, Novakova V., De La Escosura A., Zimcik P., Halaskova M., Rahali A., Almeida-Marrero V., Machacek M., Kucera R., Jamoussi B., Torres, Tomás, Novakova V., De La Escosura A., and Zimcik P.
- Published
- 2021
31. The pharmacokinetic and pharmacodynamic relationship between apraglutide and citrulline: a randomized, placebo-controlled, double-blind study in healthy volunteers
- Author
-
Bolognani, F., primary, Gal, P., additional, Moerland, M., additional, Kruithof, A., additional, van Gent, M., additional, Schulthess, P., additional, Machacek, M., additional, Greig, G., additional, Santarelli, L., additional, and Meyer, C., additional
- Published
- 2020
- Full Text
- View/download PDF
32. Fluid flow visualization by three-dimensionally reconstructed tracer path lines
- Author
-
Machacek M. and Rösgen T.
- Published
- 2003
- Full Text
- View/download PDF
33. Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled, phase II regimen-finding study
- Author
-
Rich, P., Sigurgeirsson, B., Thaci, D., Ortonne, J.-P., Paul, C., Schopf, R. E., Morita, A., Roseau, K., Harfst, E., Guettner, A., Machacek, M., and Papavassilis, C.
- Published
- 2013
- Full Text
- View/download PDF
34. Efficacy and safety results of secukinumab, a fully human monoclonal anti-interleukin-17a antibody, in the treatment of moderate-to-severe plaque psoriasis: A phase II regimen-finding trial
- Author
-
Rich, P. A., Guettner, A., Sigurgeirsson, B., Papavassilis, C., and Machacek, M.
- Published
- 2012
- Full Text
- View/download PDF
35. Quantitative Flow Visualization for Large Scale Wind Tunnels
- Author
-
Bömmels, R., primary, Machacek, M., additional, Landolt, A., additional, and Rösgen, T., additional
- Published
- 2004
- Full Text
- View/download PDF
36. PREDICTING INTRADIALYTIC HYPOTENSION FROM EXPERIENCE, STATISTICAL MODELS AND ARTIFICIAL NEURAL NETWORKS
- Author
-
Gabutti, L, Machacek, M, Marone, C, and Ferrari, P
- Published
- 2004
37. Selected blood biochemical indicators of Cherry Valley ducks undergoing fattening in relation to their diet and sex
- Author
-
Jerabek, M., primary, Suchy, P., additional, Strakova, E., additional, Kudelkova, L., additional, Simek, V., additional, Jakesova, P., additional, Machacek, M., additional, and Zapletal, D., additional
- Published
- 2018
- Full Text
- View/download PDF
38. Endoglin plays crucial role in the monocyte adhesion and transmigration via endothelial cells
- Author
-
Vicen, M., Havelek, R., Macháček, M., Tripská, K., Vitverová, B., and Nachtigal, P.
- Published
- 2020
- Full Text
- View/download PDF
39. Program and abstracts for the 2011 Meeting of the Society for Glycobiology
- Author
-
Hollingsworth, MT, Hart, GW, Paulson, JC, Stansell, E, Canis, K, Huang, IC, Panico, M, Morris, H, Haslam, S, Farzan, M, Dell, A, Desrosiers, R, von Itzstein, M, Matroscovich, M, Luther, KB, Hülsmeier, AJ, Schegg, B, Hennet, T, Nycholat, C, McBride, R, Ekiert, D, Xu, R, Peng, W, Razi, N, Gilbert, M, Wakarchuk, W, Wilson, IA, Gahlay, G, Geisler, C, Aumiller, JJ, Moremen, K, Steel, J, Labaer, J, Jarvis, DL, Drickamer, K, Taylor, M, Nizet, V, Rabinovich, G, Lewis, C, Cobb, B, Kawasaki, N, Rademacher, C, Chen, W, Vela, J, Maricic, I, Crocker, P, Kumar, V, Kronenberg, M, Paulson, J, Glenn, K, Mallinger, A, Wen, H, Srivastava, L, Tundup, S, Harn, D, Menon, AK, Yamaguchi, Y, Mkhikian, H, Grigorian, A, Li, C, Chen, HL, Newton, B, Zhou, RW, Beeton, C, Torossian, S, Tatarian, GG, Lee, SU, Lau, K, Walker, E, Siminovitch, KA, Chandy, KG, Yu, Z, Dennis, JW, Demetriou, M, Pandey, MS, Baggenstoss, BA, Washburn, JL, Weigel, PH, Chen, CI, Keusch, JJ, Klein, D, Hofsteenge, J, Gut, H, Szymanski, C, Feldman, M, Schaffer, C, Gao, Y, Strum, S, Liu, B, Schutzbach, JS, Druzhinina, TN, Utkina, NS, Torgov, VI, Szarek, WA, Wang, L, Brockhausen, I, Hitchen, P, Peyfoon, E, Meyer, B, Albers, SV, Chen, C, Newburg, DS, Jin, C, Dinglasan, RD, Beverley, SM, Guo, H, Novozhilova, N, Hickerson, S, Elnaiem, DE, Sacks, D, Turco, SJ, McKay, D, Castro, E, Takahashi, H, Straus, AH, Stalnaker, SH, Live, D, Boons, GJ, Wells, L, Stuart, R, Aoki, K, Boccuto, L, Zhang, Q, Wang, H, Bartel, F, Fan, X, Saul, R, Chaubey, A, Yang, X, Steet, R, Schwartz, C, Tiemeyer, M, Pierce, M, Kraushaar, DC, Condac, E, Nakato, H, Nishihara, S, Sasaki, N, Hirano, K, Nasirikenari, M, Collins, CC, Lau, JT, Devarapu, SK, Jeyaweerasinkam, S, Albiez, RS, Kiessling, L, Gu, J, Clark, GF, Gagneux, P, Ulm, C, Mahavadi, P, Müller, S, Rinné, S, Geyer, H, Gerardy-Schahn, R, Mühlenhoff, M, Günther, A, Geyer, R, Galuska, SP, Shibata, T, Sugihara, K, Nakayama, J, Fukuda, M, Fukuda, MN, Ishikawa, A, Terao, M, Kimura, A, Kato, A, Katayama, I, Taniguchi, N, Miyoshi, E, Aderem, A, Yoneyama, T, Angata, K, Bao, X, Chanda, S, Lowe, J, Sonon, R, Ishihara, M, Talabnin, K, Wang, Z, Black, I, Naran, R, Heiss, C, Azadi, P, Hurum, D, Rohrer, J, Balland, A, Valliere-Douglass, J, Kodama, P, Mujacic, M, Eakin, C, Brady, L, Wang, WC, Wallace, A, Treuheit, M, Reddy, P, Schuman, B, Fisher, S, Borisova, S, Coates, L, Langan, P, Evans, S, Yang, SJ, Zhang, H, Hizal, DB, Tian, Y, Sarkaria, V, Betenbaugh, M, Lütteke, T, Agravat, S, Cholleti, S, Morris, T, Saltz, J, Song, X, Cummings, R, Smith, D, Hofhine, T, Nishida, C, Mialy, R, Sophie, D, Sebastien, F, Patricia, C, Eric, S, Stephane, H, Mokros, D, Joosten, RP, Dominik, A, Vriend, G, Nguyen, LD, Martinez, J, Hinderlich, S, Reissig, HU, Reutter, W, Fan, H, Saenger, W, Moniot, S, Asada, H, Nakahara, T, Miura, Y, Stevenson, T, Yamazaki, T, De Castro, C, Burr, T, Lanzetta, R, Molinaro, A, Parrilli, M, Sule, S, Gerken, TA, Revpredo, L, Thome, J, Cardenas, G, Almeida, I, Leung, MY, Yan, S, Paschinger, K, Bleuler-Martinez, S, Jantsch, V, Wilson, I, Yoshimura, Y, Adlercreutz, D, Mannerstedt, K, Wakarchuk, WW, Dovichi, NJ, Hindsgaul, O, Palcic, MM, Chandrasekaran, A, Bharadwaj, R, Deng, K, Adams, P, Singh, A, Datta, A, Konasani, V, Imamura, A, Lowry, T, Scaman, C, Zhao, Y, Zhou, YD, Yang, K, Zhang, XL, Leymarie, N, Hartshorn, K, White, M, Cafarella, T, Seaton, B, Rynkiewicz, M, Zaia, J, Acosta-Blanco, I, Ortega-Francisco, S, Dionisio-Vicuña, M, Hernandez-Flores, M, Fuentes-Romero, L, Newburg, D, Soto-Ramirez, LE, Ruiz-Palacios, G, Viveros-Rogel, M, Tong, C, Li, W, Kong, L, Qu, M, Jin, Q, Lukyanov, P, Zhang, W, Chicalovets, I, Molchanova, V, Wu, AM, Liu, JH, Yang, WH, Nussbaum, C, Grewal, PK, Sperandio, M, Marth, JD, Yu, R, Usuki, S, Wu, HC, O'Brien, D, Piskarev, V, Ramadugu, SK, Kashyap, HK, Ghirlanda, G, Margulis, C, Brewer, C, Gomery, K, Müller-Loennies, S, Brooks, CL, Brade, L, Kosma, P, Di Padova, F, Brade, H, Evans, SV, Asakawa, K, Kawakami, K, Kushi, Y, Suzuki, Y, Nozaki, H, Itonori, S, Malik, S, Lebeer, S, Petrova, M, Balzarini, J, Vanderleyden, J, Naito-Matsui, Y, Takematsu, H, Murata, K, Kozutsumi, Y, Subedi, GP, Satoh, T, Hanashima, S, Ikeda, A, Nakada, H, Sato, R, Mizuno, M, Yuasa, N, Fujita-Yamaguchi, Y, Vlahakis, J, Nair, DG, Wang, Y, Allingham, J, Anastassiades, T, Strachan, H, Johnson, D, Orlando, R, Harenberg, J, Haji-Ghassemi, O, Mackenzie, R, Lacerda, T, Toledo, M, Straus, A, Takahashi, HK, Woodrum, B, Ruben, M, O'Keefe, B, Samli, KN, Yang, L, Woods, RJ, Jones, MB, Maxwell, J, Song, EH, Manganiello, M, Chow, YH, Convertine, AJ, Schnapp, LM, Stayton, PS, Ratner, DM, Yegorova, S, Rodriguez, MC, Minond, D, Jiménez-Barbero, J, Calle, L, Ardá, A, Gabius, HJ, André, S, Martinez-Mayorga, K, Yongye, AB, Cudic, M, Ali, MF, Chachadi, VB, Cheng, PW, Kiwamoto, T, Na, HJ, Brummet, M, Finn, MG, Hong, V, Polonskaya, Z, Bovin, NV, Hudson, S, Bochner, B, Gallogly, S, Krüger, A, Hanley, S, Gerlach, J, Hogan, M, Ward, C, Joshi, L, Griffin, M, Demarco, C, Deveny, R, Aggeler, R, Hart, C, Nyberg, T, Agnew, B, Akçay, G, Ramphal, J, Calabretta, P, Nguyen, AD, Kumar, K, Eggers, D, Terrill, R, d'Alarcao, M, Ito, Y, Vela, JL, Matsumura, F, Hoshino, H, Lee, H, Kobayashi, M, Borén, T, Jin, R, Seeberger, PH, Pitteloud, JP, Cudic, P, Von Muhlinen, N, Thurston, T, von Muhlinen, N, Wandel, M, Akutsu, M, Foeglein, AÁ, Komander, D, Randow, F, Maupin, K, Liden, D, Haab, B, Dam, TK, Brown, RK, Wiltzius, M, Jokinen, M, Andre, S, Kaltner, H, Bullen, J, Balsbaugh, J, Neumann, D, Hardie, G, Shabanowitz, J, Hunt, D, Hart, G, Mi, R, Ding, X, Van Die, I, Chapman, AB, Cummings, RD, Ju, T, Aryal, R, Ashley, J, Feng, X, Hanover, JA, Wang, P, Keembiyehetty, C, Ghosh, S, Bond, M, Krause, M, Love, D, Radhakrishnan, P, Grandgenet, PM, Mohr, AM, Bunt, SK, Yu, F, Hollingsworth, MA, Ethen, C, Machacek, M, Prather, B, Wu, Z, Kotu, V, Zhao, P, Zhang, D, van der Wel, H, Johnson, JM, West, CM, Abdulkhalek, S, Amith, SR, Jayanth, P, Guo, M, Szewczuk, M, Ohtsubo, K, Chen, M, Olefsky, J, Marth, J, Zapater, J, Foley, D, Colley, K, Kawashima, N, Fujitani, N, Tsuji, D, Itoh, K, Shinohara, Y, Nakayama, K, Zhang, L, Ten Hagen, K, Koren, S, Yehezkel, G, Cohen, L, Kliger, A, Khalaila, I, Finkelstein, E, Parker, R, Kohler, J, Sacoman, J, Badish, L, Hollingsworth, R, Tian, E, Hoffman, M, Hou, X, Tashima, Y, Stanley, P, Kizuka, Y, Kitazume, S, Yoshida, M, Kunze, A, Nasir, W, Bally, M, Hook, F, Larson, G, Mahan, A, Alter, G, Zeidan, Q, Copeland, R, Pokrovskaya, I, Willett, R, Smith, R, Morelle, W, Kudlyk, T, Lupashin, V, Vasudevan, D, Takeuchi, H, Majerus, E, Haltiwanger, RS, Boufala, S, Lee, YA, Min, D, Kim, SH, Shin, MH, Gesteira, T, Pol-Fachin, L, Coulson-Thomas, VJ, Verli, H, Nader, H, Liu, X, Yang, P, Thoden, J, Holden, H, Tytgat, H, Sánchez-Rodríguez, A, Schoofs, G, Verhoeven, T, De Keersmaecker, S, Marchal, K, Ventura, V, Sarah, N, Joann, P, Ding, Y, Jarrell, K, Cook, MC, Gibeault, S, Filippenko, V, Ye, Q, Wang, J, Kunkel, JP, Arteaga-Cabello, FJ, Arciniega-Fuentes, MT, McCoy, J, Ruiz-Palacios, GM, Francoleon, D, Loo, RO, Loo, J, Ytterberg, AJ, Kim, U, Gunsalus, R, Costello, C, Soares, R, Assis, R, Ibraim, I, Noronha, F, De Godoy, AP, Bale, MS, Xu, Y, Brown, K, Blader, I, West, C, Chen, S, Ye, X, Xue, C, Li, G, Yu, G, Yin, L, Chai, W, Gutierrez-Magdaleno, G, Tan, C, Wu, D, Li, Q, Hu, H, Ye, M, Liu, D, Mink, W, Kaese, P, Fujiwara, M, Uchimura, K, Sakai, Y, Nakada, T, Mabashi-Asazuma, H, Toth, AM, Scott, DW, Chacko, BK, Patel, RP, Batista, F, Mercer, N, Ramakrishnan, B, Pasek, M, Boeggeman, E, Verdi, L, Qasba, PK, Tran, D, Lim, JM, Liu, M, Mo, KF, Kirby, P, Yu, X, Lin, C, Costello, CE, Akama, TO, Nakamura, T, Huang, Y, Shi, X, Han, L, Yu, SH, Zhang, Z, Knappe, S, Till, S, Nadia, I, Catarello, J, Quinn, C, Julia, N, Ray, J, Tran, T, Scheiflinger, F, Szabo, C, Dockal, M, Niimi, S, Hosono, T, Michikawa, M, Kannagi, R, Takashima, S, Amano, J, Nakamura, N, Kaneda, E, Nakayama, Y, Kurosaka, A, Takada, W, Matsushita, T, Hinou, H, Nishimura, S, Igarashi, K, Abe, H, Mothere, M, Leonhard-Melief, C, Johnson, H, Nagy, T, Nairn, A, Rosa, MD, Porterfield, M, Kulik, M, Dalton, S, Pierce, JM, Hansen, SF, McAndrew, R, Degiovanni, A, McInerney, P, Pereira, JH, Hadi, M, Scheller, HV, Barb, A, Prestegard, J, Zhang, S, Jiang, J, Tharmalingam, T, Pluta, K, McGettigan, P, Gough, R, Struwe, W, Fitzpatrick, E, Gallagher, ME, Rudd, PM, Karlsson, NG, Carrington, SD, Katoh, T, Panin, V, Gelfenbeyn, K, Freire-de-Lima, L, Handa, K, Hakomori, SI, Bielik, AM, McLeod, E, Landry, D, Mendoza, V, Guthrie, EP, Mao, Y, Wang, X, Moremen, KW, Meng, L, Ramiah, AP, Gao, Z, Johnson, R, Xiang, Y, Rosa, MDEL, Wu, SC, Gilbert, HJ, Karaveg, K, Chen, L, Wang, BC, Mast, S, Sun, B, Fulton, S, Kimzey, M, Pourkaveh, S, Minalla, A, Haxo, T, Wegstein, J, Murray, AK, Nichols, RL, Giannini, S, Grozovsky, R, Begonja, AJ, Hoffmeister, KM, Suzuki-Anekoji, M, Suzuki, A, Yu, SY, Khoo, KH, van Alphen, L, Fodor, C, Wenzel, C, Ashmus, R, Miller, W, Stahl, M, Stintzi, A, Lowary, T, Wiederschain, G, Saba, J, Zumwalt, A, Meitei, NS, Apte, A, Viner, R, Gandy, M, Debowski, A, Stubbs, K, Witzenman, H, Pandey, D, Repnikova, E, Nakamura, M, Islam, R, Kc, N, Caster, C, Chaubard, JL, Krishnamurthy, C, Hsieh-Wilson, L, Pranskevich, J, Rangarajan, J, Guttman, A, Szabo, Z, Karger, B, Chapman, J, Chavaroche, A, Bionda, N, Fields, G, Jacob, F, Tse, BW, Guertler, R, Nixdorf, S, Hacker, NF, Heinzelmann-Schwarz, V, Yang, F, Kohler, JJ, Losfeld, ME, Ng, B, Freeze, HH, He, P, Wondimu, A, Liu, Y, Zhang, Y, Su, Y, Ladisch, S, Grewal, P, Mann, C, Ditto, D, Lardone, R, Le, D, Varki, N, Kulinich, A, Kostjuk, O, Maslak, G, Pismenetskaya, I, Shevtsova, A, Takeishi, S, Okudo, K, Moriwaki, K, Terao, N, Kamada, Y, Kuroda, S, Li, Y, Peiris, D, Markiv, A, Dwek, M, Adamczyk, B, Thanabalasingham, G, Huffman, J, Kattla, J, Novokmet, M, Rudan, I, Gloyn, A, Hayward, C, Reynolds, R, Hansen, T, Klimes, I, Njolstad, P, Wilson, J, Hastie, N, Campbell, H, McCarthy, M, Rudd, P, Owen, K, Lauc, G, Wright, A, Goletz, S, Stahn, R, Danielczyk, A, Baumeister, H, Hillemann, A, Löffler, A, Stöckl, L, Jahn, D, Bahrke, S, Flechner, A, Schlangstedt, M, Karsten, U, Goletz, C, Mikolajczyk, S, Ulsemer, P, Gao, N, Cline, A, Flanagan-Steet, H, Sadler, KC, Lehrman, MA, Coulson-Thomas, YM, Gesteira, TF, Mader, AM, Waisberg, J, Pinhal, MA, Friedl, A, Toma, L, Nader, HB, Mbua, EN, Johnson, S, Wolfert, M, Dimitrievska, S, Huizing, M, Niklason, L, Perdivara, I, Petrovich, R, Tokar, EJ, Waalkes, M, Fraser, P, Tomer, K, Chu, J, Rosa, S, Mir, A, Lehrman, M, Sadler, K, Lauer, M, Hascall, V, Calabro, A, Cheng, G, Swaidani, S, Abaddi, A, Aronica, M, Yuzwa, S, Shan, X, Macauley, M, Clark, T, Skorobogatko, Y, Vosseller, K, Vocadlo, D, Banerjee, A, Baksi, K, Banerjee, D, Melcher, R, Kraus, I, Moeller, D, Demmig, S, Rogoll, D, Kudlich, T, Scheppach, W, Scheurlen, M, Hasilik, A, Steirer, L, Lee, J, Moe, G, Troy, FA, Wang, F, Xia, B, Wang, B, Yi, S, Yu, H, Suzuki, M, Kobayashi, T, Sato, Y, Zhou, H, Briscoe, A, Lee, R, Wolfert, MA, Matsumoto, Y, Hamamura, K, Yoshida, T, Akita, K, Okajima, T, Furukawa, K, Urano, T, Ruhaak, LR, Miyamoto, S, and Lebrilla, CB
- Subjects
Embryogenesis ,Cancer screening ,Cancer research ,medicine ,Cell migration ,Neural cell adhesion molecule ,Biology ,medicine.disease ,Biochemistry ,Metastasis - Abstract
Cell surface mucins configure the cell surface by presenting extended protein backbones that are heavily O-glycosylated. The glycopeptide structures establish physicochemical properties at the cell surface that enable and block the formation of biologically important molecular complexes. Some mucins, such as MUC1, associate with receptor tyrosine kinases and other cell surface receptors, and engage in signal transduction in order to communicate information regarding conditions at the cell surface to the nucleus. In that context, the MUC1 cytoplasmic tail (MUC1CT) receives phosphorylation signals from receptor tyrosine kinases and serine/threonine kinases, which enables its association with different signaling complexes that conduct these signals to the nucleus and perhaps other subcellular organelles. We have detected the MUC1CT at promoters of over 500 genes, in association with several different transcription factors, and have shown that promoter occupancy can vary under different growth factor conditions. However, the full biochemical nature of the nuclear forms of MUC1 and its function at these promoter regions remain undefined. I will present evidence that nuclear forms of the MUC1CT include extracellular and cytoplasmic tail domains. In addition, I will discuss evidence for a hypothesis that the MUC1CT possesses a novel catalytic function that enables remodeling of the transcription factor occupancy of promoters, and thereby engages in regulation of gene expression.
- Published
- 2016
40. Stripped Elliptical Galaxies as Probes of ICM Physics. III. DeepChandraObservations of NGC 4552: Measuring the Viscosity of the Intracluster Medium
- Author
-
Kraft, R. P., primary, Roediger, E., additional, Machacek, M., additional, Forman, W. R., additional, Nulsen, P. E. J., additional, Jones, C., additional, Churazov, E., additional, Randall, S., additional, Su, Y., additional, and Sheardown, A., additional
- Published
- 2017
- Full Text
- View/download PDF
41. The Infall of the Virgo Elliptical Galaxy M60 toward M87 and the Gaseous Structures Produced by Kelvin–Helmholtz Instabilities
- Author
-
Wood, R. A., primary, Jones, C., additional, Machacek, M. E., additional, Forman, W. R., additional, Bogdan, A., additional, Andrade-Santos, F., additional, Kraft, R. P., additional, Paggi, A., additional, and Roediger, E., additional
- Published
- 2017
- Full Text
- View/download PDF
42. Population Modeling of Selexipag Pharmacokinetics and Clinical Response Parameters in Patients With Pulmonary Arterial Hypertension
- Author
-
Krause, A, primary, Machacek, M, additional, Lott, D, additional, Hurst, N, additional, Bruderer, S, additional, and Dingemanse, J, additional
- Published
- 2017
- Full Text
- View/download PDF
43. Endoglin Plays Role In Cholesterol-Induced Endothelial Dysfunction And Monocyte Trafficking In Human Aortic Endothelial Cells
- Author
-
Vicen, M., Havelek, R., Macháček, M., Tripská, K., Vitverová, B., and Nachtigal, P.
- Published
- 2019
- Full Text
- View/download PDF
44. MERGER HYDRODYNAMICS OF THE LUMINOUS CLUSTER RX J1347.5–1145
- Author
-
Kreisch, C. D., primary, Machacek, M. E., additional, Jones, C., additional, and Randall, S. W., additional
- Published
- 2016
- Full Text
- View/download PDF
45. NGC 5195 IN M51: FEEDBACK “BURPS” AFTER A MASSIVE MEAL?
- Author
-
Schlegel, E. M., primary, Jones, C., additional, Machacek, M., additional, and Vega, L. D., additional
- Published
- 2016
- Full Text
- View/download PDF
46. Levels of nitrogenous substances and amino acids in bodies of Ross 308 hybrid cocks and hens over the course of rearing
- Author
-
Strakova, E., primary, Suchy, P., additional, Navratil, P., additional, Herzig, I., additional, and Machacek, M., additional
- Published
- 2015
- Full Text
- View/download PDF
47. STRIPPED ELLIPTICAL GALAXIES AS PROBES OF ICM PHYSICS. I. TAILS, WAKES, AND FLOW PATTERNS IN AND AROUND STRIPPED ELLIPTICALS
- Author
-
Roediger, E., primary, Kraft, R. P., additional, Nulsen, P. E. J., additional, Forman, W. R., additional, Machacek, M., additional, Randall, S., additional, Jones, C., additional, Churazov, E., additional, and Kokotanekova, R., additional
- Published
- 2015
- Full Text
- View/download PDF
48. STRIPPED ELLIPTICAL GALAXIES AS PROBES OF ICM PHYSICS. II. STIRRED, BUT MIXED? VISCOUS AND INVISCID GAS STRIPPING OF THE VIRGO ELLIPTICAL M89
- Author
-
Roediger, E., primary, Kraft, R. P., additional, Nulsen, P. E. J., additional, Forman, W. R., additional, Machacek, M., additional, Randall, S., additional, Jones, C., additional, Churazov, E., additional, and Kokotanekova, R., additional
- Published
- 2015
- Full Text
- View/download PDF
49. Application of the Printable Etching Paste for Production of Crystalline Silicon Solar Cells with Selective Emitter by One-Step Diffusion Process
- Author
-
Cech, P., Barinka, R., Poruba, A., Machacek, M., Frantik, O., Barinkova, P., Wostry, P., Stockum, W., and Doll, O.
- Subjects
Mono- and Multicrystalline Silicon Materials and Cells ,Wafer-Based Silicon Solar Cells and Materials Technology - Abstract
25th European Photovoltaic Solar Energy Conference and Exhibition / 5th World Conference on Photovoltaic Energy Conversion, 6-10 September 2010, Valencia, Spain; 2321-2324, Standard solar cells from p-type crystalline silicon are produced with homogeneously doped n-type emitter with typical sheet resistance 40-60W/sq. Cell structures with selective emitter achieve better performances due to decreasing front recombination velocity (Auger and surface recombination). More complicated process technology with two phosphorus diffusion and masking steps is disadvantageous of cell structures with selective emitter. This paper is presented with the aim to achieve a simplified process for selective emitter structures in only one phosphorus diffusion step and subsequent local application of printable etching paste.
- Published
- 2010
- Full Text
- View/download PDF
50. Influence of Rapid Thermal Annealing on Silicon Wafers with Swirls
- Author
-
Frantik, O., Barinka, R., Wostry, P., and Machacek, M.
- Subjects
Mono- and Multicrystalline Silicon Materials and Cells ,Wafer-Based Silicon Solar Cells and Materials Technology - Abstract
25th European Photovoltaic Solar Energy Conference and Exhibition / 5th World Conference on Photovoltaic Energy Conversion, 6-10 September 2010, Valencia, Spain; 2525-2527, We can use Rapid Thermal Annealing (RTA) for silicon wafers treatment to achieve better bulk properties. Rapid change of temperature has specific influence on different wafers behavior in RTP technology in the contrast to the standard heating technology. Rapid temperature change can be followed besides positive effects by creation of stresses and defects in the silicon substrate. This paper is focused on annealing by RTP. Wafers were p-type monocrystalline CZ silicon with different bulk minority carrier lifetime and with swirls. Minority carrier lifetime was measured by MW-PCD (Microwave Photoconductance Decay) before and after thermal processing. The influence of key RTP parameterson minority carrier lifetime was investigated. These parameters are maximum temperature, rate of ramp up/down temperature and plateau time. The influence RTP parameters was investigated with the aid of factor analyse. The maximum annealing temperature is the key parameter for high minority carrier lifetime. The other experiment was designed for evaluation of obtained experiences. Seven thermal profiles with different peak temperature were investigated within the experiment. We find out that minority carrier lifetime decreases after annealing at 1020°C from initial value of 66 μs to the level of 9 μs. On the other hand annealing at temperature of 310°C was the cause of minority carrier lifetime increase from initial value of 29 μs to the 285 μs. Thermal profile with the lowest temperature was the best for increasing of minority carrier lifetime. These effects depends also on high bulk minority carrier lifetime before annealing. Influence of heat treatment at different temperatures and under different processing conditions on substrates behavior will be discussed.
- Published
- 2010
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.