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p. 246-250 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-05-13T13:29:36Z No. of bitstreams: 1 1417-15570-1-PB.pdf: 207340 bytes, checksum: 56a41fee5029c0c65d214f0b942072a9 (MD5) Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-07-09T12:11:04Z (GMT) No. of bitstreams: 1 1417-15570-1-PB.pdf: 207340 bytes, checksum: 56a41fee5029c0c65d214f0b942072a9 (MD5) Made available in DSpace on 2014-07-09T12:11:04Z (GMT). No. of bitstreams: 1 1417-15570-1-PB.pdf: 207340 bytes, checksum: 56a41fee5029c0c65d214f0b942072a9 (MD5) Previous issue date: 2013 Introducción: La insuficiencia cardíaca con función sistólica preservada es un síndrome clínico con los mismos signos y síntomas de la insuficiencia cardíaca clásica. La enfermedad de Chagas es una causa importante de insuficiencia cardíaca en América Latina, que se asocia con miocardiopatía dilatada y deterioro progresivo de la función sistólica. No existen estudios previos que hayan evaluado pacientes con insuficiencia cardíaca y función sistólica preservada de una zona endémica en la cual la enfermedad de Chagas es la causa principal de insuficiencia cardíaca. Objetivo: Comparar las características clínicas y la evolución de la insuficiencia cardíaca en pacientes con disfunción sistólica y con función sistólica preservada en una población con alta prevalencia de enfermedad de Chagas. Material y métodos: Se realizó una evaluación prospectiva de los pacientes con diagnóstico clínico de insuficiencia cardíaca que ingresaron a un centro de referencia en Salvador, Bahía (Brasil). Se consideró función sistólica preservada a una fracción de eyección del ventrículo izquierdo mayor del 45% por ecocardiograma. Se realizó seguimiento al año a través de contacto telefónico o entrevista personal en el consultorio de insuficiencia cardíaca. Resultados: Se incluyeron 383 pacientes durante un período de 16 meses; el 52,5% eran hombres y la edad media fue de 54,2 años. La función sistólica estuvo preservada en 138 pacientes (36%). La enfermedad de Chagas fue la principal etiología de ambos tipos de insuficiencia cardíaca (45,3% con disfunción sistólica y 44,2% con función sistólica preservada). El 93,5% (358) de los pacientes completaron un año de seguimiento. Los pacientes con enfermedad de Chagas y función sistólica preservada tuvieron menor mortalidad que los pacientes con disfunción sistólica (10% vs. 23,6%; p = 0,039). En los pacientes sin enfermedad de Chagas y función sistólica preservada, la mortalidad fue similar a la de aquellos con disfunción sistólica (10,4% vs. 15,8%; p = 0,307). Conclusiones: La función sistólica preservada fue muy frecuente en nuestra población. La enfermedad de Chagas es la principal etiología de insuficiencia cardíaca independientemente de la fracción de eyección del ventrículo izquierdo. Los pacientes con enfermedad de Chagas y función sistólica preservada tienen mejor pronóstico que aquellos con disfunción sistólica, probablemente porque se encuentran en la fase inicial del compromiso cardíaco.

INTRODUÇÃO: A doença cardíaca valvar é um grave problema de saúde pública, mais frequente em países em desenvolvimento, acometendo indivíduos em idade laboralmente produtiva. OBJETIVO: Avaliar o perfil socioeconômico e epidemiológico dos pacientes submetidos a cirurgia valvar e a sua relação com os tipos de próteses utilizadas em um centro de referência público de Salvador, BA, Brasil. MÉTODOS: Estudo de corte transversal descritivo de prevalência, no qual foram analisados retrospectivamente idade, sexo, procedência, tipo de valvopatia, cirurgia a qual o paciente foi submetido e o tipo de prótese utilizada em casos de trocas, em centro de referência público de cardiologia. RESULTADOS: Foram revisados 366 prontuários, de todos os pacientes submetidos a cirurgia de valva cardíaca, de janeiro de 2007 a dezembro de 2009. Em relação ao sexo, 52% dos pacientes eram do sexo feminino. A idade média ± DP foi de 41,70 ± 17,85 anos. Dentre os pacientes, 37,7% eram procedentes da capital e 62,3%, do interior do estado da Bahia (Brasil). A troca valvar foi realizada em 73% dos pacientes, enquanto que 7,38% realizaram plastia valvar e 18,3% realizaram tanto plastia quanto troca. Dos pacientes que realizaram troca valvar, 70% receberam bioprótese e 30% do tipo metálica, com predominância do uso bioprótese nas faixas etárias jovens (P

p. 1-7 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-12T16:36:07Z No. of bitstreams: 1 Ronaldo L. Oliveira.pdf: 700877 bytes, checksum: b4bfdf34c0cb2047c8f1ffc8d0aadacb (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-08-13T16:11:16Z (GMT) No. of bitstreams: 1 Ronaldo L. Oliveira.pdf: 700877 bytes, checksum: b4bfdf34c0cb2047c8f1ffc8d0aadacb (MD5) Made available in DSpace on 2014-08-13T16:11:16Z (GMT). No. of bitstreams: 1 Ronaldo L. Oliveira.pdf: 700877 bytes, checksum: b4bfdf34c0cb2047c8f1ffc8d0aadacb (MD5) Previous issue date: 2012-04 Background Aging and migration have brought changes to the epidemiology and stroke has been shown to be independently associated with Chagas disease. We studied stroke correlates in cardiomyopathy patients with focus on the chagasic etiology. Methodology/Principal Findings We performed a cross-sectional review of medical records of 790 patients with a cardiomyopathy. Patients with chagasic (329) and non-chagasic (461) cardiomyopathies were compared. There were 108 stroke cases, significantly more frequent in the Chagas group (17.3% versus 11.1%; p

p.328-331 Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-06-29T19:40:29Z No. of bitstreams: 1 Macedo, Cristiano Ricardo Bastos de.pdf: 1890586 bytes, checksum: 8587af29f6b3df1cab439013e3b27e4c (MD5) Made available in DSpace on 2012-06-29T19:40:29Z (GMT). No. of bitstreams: 1 Macedo, Cristiano Ricardo Bastos de.pdf: 1890586 bytes, checksum: 8587af29f6b3df1cab439013e3b27e4c (MD5) Previous issue date: 2011-10 Objective - To evaluate the frequency of oral antihypertensive medication preceding the increase in blood pressure in patients in a university hospital, the drug of choice, and the maintained use of antihypertensive medication. Methods - Data from January to June 1997 from the University Hospital Professor Edgard Santos Pharmacy concerning the prescriptions of all inpatients were used. Variables included in the analysis were: antihypertensive medication prescription preceding increase in blood pressure, type of antihypertensive medication, gender, clinical or surgical wards, and the presence of maintained antihypertensive medication. Results - The hospital admitted 2,532 patients, 1,468 in surgical wards and 818 in medical wards. Antihypertensive medication prescription preceding pressure increase was observed in 578 patients (22.8%). Nifedipine was used in 553(95.7%) and captopril in 25 (4.3%). In 50.7% of patients, prescription of antihypertensive medication was not associated with maintained antihypertensive medication. Prescription of antihypertensive drugs preceding elevation of blood pressure was significantly (p

FUNDAMENTOS: Insuficiência cardíaca (IC) é uma doença comum com alta taxa de mortalidade. Anemia e insuficiência renal (IR) são frequentemente encontradas em portadores de IC associadas com maior gravidade da doença cardíaca e pior prognóstico. OBJETIVO: Avaliar a prevalência de anemia e insuficiência renal, bem como a associação entre esses dois quadros, em portadores de IC não hospitalizados. MÉTODOS: Foram observados pacientes acompanhandos na clínica de IC de um hospital universitário de julho de 2003 a novembro de 2006. Anemia foi definida como níveis de hemoglobina abaixo de 13 mg/dl para homens e de 12 mg/dl para mulheres. A função renal foi avaliada por meio da taxa de filtração glomerular (TFG), calculada pela fórmula simplificada do estudo MDRD (Modification of Diet in Renal Disease). RESULTADOS: Dos trezentos e quarenta e cinco pacientes incluídos neste estudo, 26,4% (n = 91) tinham anemia e 29,6% tinham insuficiência renal moderada a grave (TFG < 60 ml/min). A associação entre anemia e maior prevalência de insuficiência renal foi estatisticamente significante (41,8% vs. 25,2%; p = 0,005). Os pacientes em classe funcional III e IV apresentaram maior incidência de anemia (39,0% vs. 19,4%; p

p.249-254 Submitted by Texeira Ana (atanateixeira@gmail.com) on 2012-06-21T12:48:41Z No. of bitstreams: 1 Reis, Francisco José Farias Borges dos.pdf: 486859 bytes, checksum: 9ba08b4e18dac6831ae35a77f0f87268 (MD5) Made available in DSpace on 2012-06-21T12:48:41Z (GMT). No. of bitstreams: 1 Reis, Francisco José Farias Borges dos.pdf: 486859 bytes, checksum: 9ba08b4e18dac6831ae35a77f0f87268 (MD5) Previous issue date: 2009 Background: Heart Failure (HF) is a common disease with a high rate of mortality. Anemia and renal failure (RF) are often found in patients with HF associated with higher severity of the heart disease and a worse prognosis. Objective: To evaluate the prevalence of anemia and RF, as well as the association between these two conditions, in non-hospitalized patients with HF. Methods: Patients treated at the HF Outpatient Clinic of a university hospital were followed from July 2003 to November 2006. Anemia was defined as hemoglobin levels < 13 mg/dl for men and 12 mg/dl for women. Renal function was assessed by the glomerular filtration rate (GFR), calculated by the simplified formula of the MDRD (Modification of Diet in Renal Disease) study. Results: Of the 345 patients included in this study, 26.4% (n = 91) had anemia and 29.6% had moderate to severe renal failure (GFR < 60 ml/min). The association between anemia and a higher prevalence of renal failure was statistically significant (41.8% vs. 25.2%; p = 0.005). The patients at functional class III and IV presented a higher incidence of anemia (39.0% vs. 19.4%; p

Texto completo: acesso restrito. p.345–352 Submitted by Suelen Reis (suelen_suzane@hotmail.com) on 2013-01-28T14:57:07Z No. of bitstreams: 1 Macedo.pdf: 322808 bytes, checksum: f572799517326422635af7118e8aca98 (MD5) Made available in DSpace on 2013-01-28T14:57:07Z (GMT). No. of bitstreams: 1 Macedo.pdf: 322808 bytes, checksum: f572799517326422635af7118e8aca98 (MD5) Previous issue date: 1998 Objective: The purpose of this study was to compare the effect of three groups of anti-resorptive drugs in post-menopausal osteoporosis. Data sources: We collected data covering the period between 1983 and 1995, by first using MEDLINE. References retrieved were scanned further to identify additional papers. Study selection: Only randomized studies evaluating bone mass by means of dual-photon or dual energy densitometry over a period of 1 year were accepted. Data extraction: Studies were arranged into three drug groups. We used densitometry results after 1 year in all treatment or control groups. Factors which might interfere with the results were recorded for subsequent separate analysis. Data synthesis: The MEDLINE search identified almost 25,000 studies. On reading the abstracts, 275 trials appeared to be controlled trials and original copies were retrieved for detailed analysis. A total of 31 articles which satisfied the inclusion criteria were identified. The first meta-analysis included studies which compared oestrogens and placebo, and the global effect-size was 0·54 (95% CI 0·34, 0·73). The second meta-analysis compared calcitonins with placebo and produced an effect-size of 0·41 (95% CI 0·21, 0·61) The third analysis compared bisphosphonates and placebo and showed an effect-size of 0·87 (95% CI 0·68, 1·07). Only oestrogen dose affected the results found. Conclusions: Bisphosphonates had the greatest effect on bone mass in post-menopausal osteoporosis.