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1. Evaluating a novel model of hepatitis B care, Hep B PAST, in the Northern Territory of Australia: results from a prospective, population-based study

Author

Hosking, Kelly, Binks, Paula, De Santis, Teresa, Wilson, Phillip Merrdi, Gurruwiwi, George Garambaka, Bukulatjpi, Sarah Mariyalawuy, Vintour-Cesar, Emily, McKinnon, Melita, Nihill, Peter, Fernandes, Tammy-Allyn, Greenwood-Smith, Belinda, Batey, Robert, Ross, Cheryl, Tong, Steven Y.C., Stewart, Geoffrey, Marshall, Catherine, Gargan, Catherine, Manchikanti, Prashanti, Fuller, Karen, Tate-Baker, Jaclyn, Stewart, Sami, Cowie, Benjamin, Allard, Nicole, MacLachlan, Jennifer H., Qama, Ashleigh, Boettiger, David, Davis, Joshua S., Connors, Christine, and Davies, Jane

Published
2024
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4. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Sheena, Brittney S, Hiebert, Lindsey, Han, Hannah, Ippolito, Helen, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdoli, Amir, Abubaker Ali, Hiwa, Adane, Mesafint Molla, Adegboye, Oyelola A, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afzal, Muhammad Sohail, Afzal, Saira, Aghaie Meybodi, Mohamad, Ahadinezhad, Bahman, Ahinkorah, Bright Opoku, Ahmad, Sajjad, Ahmad, Tauseef, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Akalu, Gizachew Taddesse, Aklilu, Addis, Akram, Tayyaba, Al Hamad, Hanadi, Alahdab, Fares, Alem, Adugnaw Zeleke, Alem, Dejene Tsegaye, Alhalaiqa, Fadwa Alhalaiqa Naji, Alhassan, Robert Kaba, Ali, Liaqat, Ali, Muhammad Ashar, Alimohamadi, Yousef, Alipour, Vahid, Alkhayyat, Motasem, Almustanyir, Sami, Al-Raddadi, Rajaa M, Altawalah, Haya, Amini, Saeed, Amu, Hubert, Ancuceanu, Robert, Andrei, Catalina Liliana, Andrei, Tudorel, Anoushiravani, Amir, Ansar, Adnan, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-Zozani, Morteza, Argaw, Ayele Mamo, Argaw, Zeleke Gebru, Arshad, Muhammad, Artamonov, Anton A, Ashraf, Tahira, Atlaw, Daniel, Ausloos, Floriane, Ausloos, Marcel, Azadnajafabad, Sina, Azangou-Khyavy, Mohammadreza, Azari Jafari, Amirhossein, Azarian, Ghasem, Bagheri, Sayna, Bahadory, Saeed, Baig, Atif Amin, Banach, Maciej, Barati, Nastaran, Barrow, Amadou, Batiha, Abdul-Monim Mohammad, Bejarano Ramirez, Diana Fernanda, Belgaumi, Uzma Iqbal, Berhie, Alemshet Yirga, Bhagat, Devidas S, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhojaraja, Vijayalakshmi S, Bijani, Ali, Biondi, Antonio, Bodicha, Belay Boda Abule, Bojia, Hunduma Amensisa, Boloor, Archith, Bosetti, Cristina, Braithwaite, Dejana, Briko, Nikolay Ivanovich, Butt, Zahid A, Cámera, Luis Alberto, Chakinala, Raja Chandra, Chakraborty, Promit Ananyo, Charan, Jaykaran, Chen, Shu, Choi, Jee-Young Jasmine, Choudhari, Sonali Gajanan, Chowdhury, Fazle Rabbi, Chu, Dinh-Toi, Chung, Sheng-Chia, Cortesi, Paolo Angelo, Cowie, Benjamin C, Culbreth, Garland T, Dadras, Omid, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, De la Hoz, Fernando Pio, Debela, Sisay Abebe, Dedefo, Mohammed Gebre, Demeke, Feleke Mekonnen, Demie, Takele Gezahegn G, Demissie, Getu Debalkie, Derbew Molla, Meseret, Desta, Abebaw Alemayehu, Dhamnetiya, Deepak, Dhimal, Mandira Lamichhane, Dhimal, Meghnath, Didehdar, Mojtaba, Doan, Linh Phuong, Dorostkar, Fariba, Drake, Thomas M, Eghbalian, Fatemeh, Ekholuenetale, Michael, El Sayed, Iman, El Sayed Zaki, Maysaa, Elhadi, Muhammed, Elmonem, Mohamed A, Elsharkawy, Aisha, Enany, Shymaa, Enyew, Daniel Berhanie, Erkhembayar, Ryenchindorj, Eskandarieh, Sharareh, Esmaeilzadeh, Firooz, Ezzikouri, Sayeh, Farrokhpour, Hossein, Fetensa, Getahun, Fischer, Florian, Foroutan, Masoud, Gad, Mohamed M, Gaidhane, Abhay Motiramji, Gaidhane, Shilpa, Galles, Natalie C, Gallus, Silvano, Gebremeskel, Teferi Gebru, Gebreyohannes, Eyob Alemayehu, Ghadiri, Keyghobad, Ghaffari, Kazem, Ghafourifard, Mansour, Ghamari, Seyyed-Hadi, Ghashghaee, Ahmad, Gholami, Ali, Gholizadeh, Abdolmajid, Gilani, Aima, Goel, Amit, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Gorini, Giuseppe, Goshu, Yitayal Ayalew, Griswold, Max G, Gubari, Mohammed Ibrahim Mohialdeen, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Haddadi, Rasool, Halwani, Rabih, Hamid, Saeed S, Hamidi, Samer, Hanif, Asif, Haque, Shafiul, Harapan, Harapan, Hargono, Arief, Hariri, Sanam, Hasaballah, Ahmed I, Hasan, S M Mahmudul, Hassanipour, Soheil, Hassankhani, Hadi, Hay, Simon I, Hayat, Khezar, Heidari, Golnaz, Herteliu, Claudiu, Heyi, Demisu Zenbaba, Hezam, Kamal, Holla, Ramesh, Hosseini, Mohammad-Salar, Hosseini, Mostafa, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Househ, Mowafa, Huang, Junjie, Hussein, Nawfal R, Iavicoli, Ivo, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Irham, Lalu Muhammad, Islam, Jessica Y, Ismail, Nahlah Elkudssiah, Jacobsen, Kathryn H, Jadidi-Niaragh, Farhad, Javadi Mamaghani, Amirreza, Jayaram, Shubha, Jayawardena, Ranil, Jebai, Rime, Jha, Ravi Prakash, Joseph, Nitin, Joukar, Farahnaz, Kaambwa, Billingsley, Kabir, Ali, Kabir, Zubair, Kalhor, Rohollah, Kandel, Himal, Kanko, Tesfaye K Tesfaye, Kantar, Rami S, Karaye, Ibraheem M, Kassa, Bekalu Getnet, Kemp Bohan, Phillip M, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khan, Gulfaraz, Khan, Imteyaz A, Khan, Junaid, Khan, Moien AB, Khanali, Javad, Khater, Amir M, Khatib, Mahalaqua Nazli, Khodadost, Mahmoud, Khoja, Abdullah T, Khosravizadeh, Omid, Khubchandani, Jagdish, Kim, Gyu Ri, Kim, Hanna, Kim, Min Seo, Kim, Yun Jin, Kocarnik, Jonathan M, Kolahi, Ali-Asghar, Koteeswaran, Rajasekaran, Kumar, G Anil, La Vecchia, Carlo, Lal, Dharmesh Kumar, Landires, Iván, Lasrado, Savita, Lazarus, Jeffrey V, Ledda, Caterina, Lee, Doo Woong, Lee, Sang-woong, Lee, Yeong Yeh, Levi, Miriam, Li, Jiarui, Lim, Stephen S, Lobo, Stany W, Lopukhov, Platon D, Loureiro, Joana A, MacLachlan, Jennifer H, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Majeed, Azeem, Makki, Alaa, Malekpour, Mohammad-Reza, Malekzadeh, Reza, Malik, Ahmad Azam, Mansour-Ghanaei, Fariborz, Mansournia, Mohammad Ali, Martins-Melo, Francisco Rogerlândio, Matthews, Philippa C, Mendoza, Walter, Menezes, Ritesh G, Meretoja, Tuomo J, Mersha, Amanual Getnet, Mestrovic, Tomislav, Miller, Ted R, Minh, Le Huu Nhat, Mirica, Andreea, Mirmoeeni, Seyyedmohammadsadeq, Mirrakhimov, Erkin M, Misra, Sanjeev, Mithra, Prasanna, Moazen, Babak, Mohamadkhani, Ashraf, Mohammadi, Mokhtar, Mohammed, Shafiu, Moka, Nagabhishek, Mokdad, Ali H, Moludi, Jalal, Momtazmanesh, Sara, Monasta, Lorenzo, Moradi, Ghobad, Moradzadeh, Maliheh, Moradzadeh, Rahmatollah, Moraga, Paula, Mostafavi, Ebrahim, Mubarik, Sumaira, Muniyandi, Malaisamy, Murray, Christopher J L, Naghavi, Mohsen, Naimzada, Mukhammad David, Narasimha Swamy, Sreenivas, Natto, Zuhair S, Nayak, Biswa Prakash, Nazari, Javad, Negoi, Ionut, Negru, Serban Mircea, Nejadghaderi, Seyed Aria, Neupane Kandel, Sandhya, Nguyen, Huong Lan Thi, Ngwa, Che Henry, Niazi, Robina Khan, Nnaji, Chukwudi A, Noubiap, Jean Jacques, Nowroozi, Ali, Nuñez-Samudio, Virginia, Oancea, Bogdan, Ochir, Chimedsuren, Odukoya, Oluwakemi Ololade, Oh, In-Hwan, Olagunju, Andrew T, Olakunde, Babayemi Oluwaseun, Omar Bali, Ahmed, Omer, Emad, Otstavnov, Stanislav S, Oumer, Bilcha, Padubidri, Jagadish Rao, Pana, Adrian, Pandey, Anamika, Park, Eun-Cheol, Pashazadeh Kan, Fatemeh, Patel, Urvish K, Paudel, Uttam, Petcu, Ionela-Roxana, Piracha, Zahra Zahid, Pollok, Richard Charles G, Postma, Maarten J, Pourshams, Akram, Poustchi, Hossein, Rabiee, Mohammad, Rabiee, Navid, Rafiei, Alireza, Rafiei, Sima, Raghuram, Pavan Manibettu, Rahman, Mosiur, Rahmani, Amir Masoud, Rahmawaty, Setyaningrum, Rajesh, Aashish, Ranasinghe, Priyanga, Rao, Chythra R, Rao, Sowmya J, Rashidi, Mahsa, Rashidi, Mohammad-Mahdi, Rawaf, David Laith, Rawaf, Salman, Rawassizadeh, Reza, Rezaei, Negar, Rezapour, Aziz, Rezazadeh-Khadem, Sahba, Rodriguez, Jefferson Antonio Buendia, Rwegerera, Godfrey M, Sabour, Siamak, Saddik, Basema, Saeb, Mohammad Reza, Saeed, Umar, Sahebkar, Amirhossein, Saif-Ur-Rahman, KM, Salahi, Sarvenaz, Salimzadeh, Hamideh, Sampath, Chethan, Samy, Abdallah M, Sanabria, Juan, Sanmarchi, Francesco, Santric-Milicevic, Milena M, Sarveazad, Arash, Sathian, Brijesh, Sawhney, Monika, Seidu, Abdul-Aziz, Sepanlou, Sadaf G, Seylani, Allen, Shahabi, Saeed, Shaikh, Masood Ali, Shaker, Elaheh, Shakhmardanov, Murad Ziyaudinovich, Shannawaz, Mohammed, Shenoy, Suchitra M, Shetty, Jeevan K, Shetty, Pavanchand H, Shibuya, Kenji, Shin, Jae Il, Shobeiri, Parnian, Sibhat, Migbar Mekonnen, Singh, Achintya Dinesh, Singh, Jasvinder A, Singh, Surjit, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sohrabpour, Amir Ali, Song, Suhang, Tabaeian, Seidamir Pasha, Tadesse, Eyayou Girma, Taheri, Majid, Tampa, Mircea, Tan, Ker-Kan, Tavakoli, Ahmad, Tbakhi, Abdelghani, Tefera, Belay Negash, Tehrani-Banihashemi, Arash, Tesfaw, Habtamu Molla, Thapar, Rekha, Thavamani, Aravind, Tohidast, Seyed Abolfazl, Tollosa, Daniel Nigusse, Tosti, Maria Elena, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Mai Thi Ngoc, Trihandini, Indang, Tusa, Biruk Shalmeno, Ullah, Irfan, Vacante, Marco, Valadan Tahbaz, Sahel, Valdez, Pascual R, Varthya, Shoban Babu, Vo, Bay, Waheed, Yasir, Weldesenbet, Adisu Birhanu, Woldemariam, Melat, Xu, Suowen, Yahyazadeh Jabbari, Seyed Hossein, Yaseri, Mehdi, Yeshaw, Yigizie, Yiğit, Vahit, Yirdaw, Birhanu Wubale, Yonemoto, Naohiro, Yu, Chuanhua, Yunusa, Ismaeel, Zahir, Mazyar, Zaki, Leila, Zamani, Mohammad, Zamanian, Maryam, Zastrozhin, Mikhail Sergeevich, Vos, Theo, Ward, John W, and Dirac, M Ashworth

Published
2022
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5. Hepatitis B clinical care provision in pregnancy: A whole‐of‐population linkage study in Victoria, Australia.

Author

MacLachlan, Jennifer H, Romero, Nicole, Allard, Nicole, Rowe, Stacey L, and Cowie, Benjamin C

Subjects
*CHRONIC hepatitis B, *GENERAL practitioners, *VIRAL load, *CLINICAL medicine, *HEPATITIS B
Abstract

Background and Aim Methods Results Conclusions Pregnancy is a key setting for engagement in chronic hepatitis B (CHB) care, due to the implications for transmission to the infant and antenatal diagnosis representing an opportunity for ongoing follow‐up. This study aimed to identify the coverage and predictors of clinical care for women with CHB during and after pregnancy in a population‐level cohort.Notified CHB cases in Victoria, Australia, were linked with hospitalizations, medical services, and prescribing data, covering the period 1991–2018. Women with an admission for a live birth were identified and services provided during pregnancy were assessed, including general practitioner (GP) or specialist visits, viral load and serology testing, and antiviral treatment. Viral load and serology testing coverage ware also assessed for the 2‐year period following pregnancy. Demographic and clinical predictors of viral load testing during pregnancy were assessed.A total of 11 015 birth events occurred for 6090 women with CHB. During pregnancy most had a GP consultation (91.6%); however, only 39.5% had viral load testing and 41.4% had a gastroenterology or infectious diseases specialist consultation. Viral load testing and serology testing in the 2 years after pregnancy occurred in approximately half (47.9% and 52.2%, respectively) with increases over time. Viral load testing was more likely in those born overseas, those with more than one previous birth, and those living in Melbourne.Despite improvements over time, key gaps were identified in the provision of CHB clinical care during and after pregnancy, with implications for ongoing transmission and adverse outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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7. The cascade of care for hepatitis C in Victoria, Australia: a data linkage cohort study.

Author

Snow, Kathryn, MacLachlan, Jennifer H., Rowe, Stacey, Higgins, Nasra, and Cowie, Benjamin C.

Subjects
*RESEARCH funding, *HEPATITIS viruses, *MEDICAL care, *PATIENT care, *CONTINUUM of care, *RETROSPECTIVE studies, *DESCRIPTIVE statistics, *LONGITUDINAL method, *ANTIVIRAL agents, *MEDICAL records, *ACQUISITION of data, *VIREMIA, *INFORMATION retrieval, *HEPATITIS C, *CONFIDENCE intervals
Abstract

Background: Highly effective hepatitis C therapies are available in Australia. However, people living with hepatitis C face various barriers to accessing care and treatment. Aims: To identify gaps in the cascade of care for hepatitis C and generate estimates of the number living with untreated infection according to population group, using a representative longitudinal study population. Methods: We linked hepatitis C notification data from Victoria to national pathology, prescribing and death registry data. We assessed receipt of key clinical services in a large cohort who tested positive for hepatitis C from 1 January 2000 to 31 December 2016, with follow‐up to 30 June 2018. We estimated the number still living with hepatitis C, adjusting for spontaneous clearance and mortality. Results: The cohort comprised 45 391 people positive for hepatitis C. Of these, 13 346 (29%) received treatment and an estimated 28% (95% confidence interval (CI): 26–30%) were still living with chronic infection at 30 June 2018, with the remainder still living following spontaneous clearance (30%, 95% CI: 29–32%) or having died (12%, 95% CI: 12–12%). Half (50%) of those still living with hepatitis C were born from 1965 to 1980, and 74% first tested positive before 2011. Conclusions: Despite an enabling policy environment and subsidised therapy, many people in this cohort were not treated. Increased measures may be needed to engage people in care, including those who acquired hepatitis C more than 10 years ago. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Author

Wang, Haidong, Naghavi, Mohsen, Allen, Christine, Barber, Ryan M, Bhutta, Zulfiqar A, Carter, Austin, Casey, Daniel C, Charlson, Fiona J, Chen, Alan Zian, Coates, Matthew M, Coggeshall, Megan, Dandona, Lalit, Dicker, Daniel J, Erskine, Holly E, Ferrari, Alize J, Fitzmaurice, Christina, Foreman, Kyle, Forouzanfar, Mohammad H, Fraser, Maya S, Fullman, Nancy, Gething, Peter W, Goldberg, Ellen M, Graetz, Nicholas, Haagsma, Juanita A, Hay, Simon I, Huynh, Chantal, Johnson, Catherine O, Kassebaum, Nicholas J, Kinfu, Yohannes, Kulikoff, Xie Rachel, Kutz, Michael, Kyu, Hmwe H, Larson, Heidi J, Leung, Janni, Liang, Xiaofeng, Lim, Stephen S, Lind, Margaret, Lozano, Rafael, Marquez, Neal, Mensah, George A, Mikesell, Joe, Mokdad, Ali H, Mooney, Meghan D, Nguyen, Grant, Nsoesie, Elaine, Pigott, David M, Pinho, Christine, Roth, Gregory A, Salomon, Joshua A, Sandar, Logan, Silpakit, Naris, Sligar, Amber, Sorensen, Reed J D, Stanaway, Jeffrey, Steiner, Caitlyn, Teeple, Stephanie, Thomas, Bernadette A, Troeger, Christopher, VanderZanden, Amelia, Vollset, Stein Emil, Wanga, Valentine, Whiteford, Harvey A, Wolock, Timothy, Zoeckler, Leo, Abate, Kalkidan Hassen, Abbafati, Cristiana, Abbas, Kaja M, Abd-Allah, Foad, Abera, Semaw Ferede, Abreu, Daisy M X, Abu-Raddad, Laith J, Abyu, Gebre Yitayih, Achoki, Tom, Adelekan, Ademola Lukman, Ademi, Zanfina, Adou, Arsène Kouablan, Adsuar, José C, Afanvi, Kossivi Agbelenko, Afshin, Ashkan, Agardh, Emilie Elisabet, Agarwal, Arnav, Agrawal, Anurag, Kiadaliri, Aliasghar Ahmad, Ajala, Oluremi N, Akanda, Ali Shafqat, Akinyemi, Rufus Olusola, Akinyemiju, Tomi F, Akseer, Nadia, Lami, Faris Hasan Al, Alabed, Samer, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore K M, Alasfoor, Deena, Aldhahri, Saleh Fahed, Aldridge, Robert William, Alegretti, Miguel Angel, Aleman, Alicia V, Alemu, Zewdie Aderaw, Alexander, Lily T, Alhabib, Samia, Ali, Raghib, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Al-Raddadi, Rajaa, Alsharif, Ubai, Altirkawi, Khalid A, Martin, Elena Alvarez, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amegah, Adeladza Kofi, Ameh, Emmanuel A, Amini, Heresh, Ammar, Walid, Amrock, Stephen Marc, Andersen, Hjalte H, Anderson, Benjamin O, Anderson, Gregory M, Antonio, Carl Abelardo T, Aregay, Atsede Fantahun, Ärnlöv, Johan, Arsenijevic, Valentina S Arsic, Artaman, Al, Asayesh, Hamid, Asghar, Rana Jawad, Atique, Suleman, Avokpaho, Euripide Frinel G Arthur, Awasthi, Ashish, Azzopardi, Peter, Bacha, Umar, Badawi, Alaa, Bahit, Maria C, Balakrishnan, Kalpana, Banerjee, Amitava, Barac, Aleksandra, Barker-Collo, Suzanne L, Bärnighausen, Till, Barregard, Lars, Barrero, Lope H, Basu, Arindam, Basu, Sanjay, Bayou, Yibeltal Tebekaw, Bazargan-Hejazi, Shahrzad, Beardsley, Justin, Bedi, Neeraj, Beghi, Ettore, Belay, Haileeyesus Adamu, Bell, Brent, Bell, Michelle L, Bello, Aminu K, Bennett, Derrick A, Bensenor, Isabela M, Berhane, Adugnaw, Bernabé, Eduardo, Betsu, Balem Demtsu, Beyene, Addisu Shunu, Bhala, Neeraj, Bhalla, Ashish, Biadgilign, Sibhatu, Bikbov, Boris, Abdulhak, Aref A Bin, Biroscak, Brian J, Biryukov, Stan, Bjertness, Espen, Blore, Jed D, Blosser, Christopher D, Bohensky, Megan A, Borschmann, Rohan, Bose, Dipan, Bourne, Rupert R A, Brainin, Michael, Brayne, Carol E G, Brazinova, Alexandra, Breitborde, Nicholas J K, Brenner, Hermann, Brewer, Jerry D, Brown, Alexandria, Brown, Jonathan, Brugha, Traolach S, Buckle, Geoffrey Colin, Butt, Zahid A, Calabria, Bianca, Campos-Nonato, Ismael Ricardo, Campuzano, Julio Cesar, Carapetis, Jonathan R, Cárdenas, Rosario, Carpenter, David O, Carrero, Juan Jesus, Castañeda-Orjuela, Carlos A, Rivas, Jacqueline Castillo, Catalá-López, Ferrán, Cavalleri, Fiorella, Cercy, Kelly, Cerda, Jorge, Chen, Wanqing, Chew, Adrienne, Chiang, Peggy Pei-Chia, Chibalabala, Mirriam, Chibueze, Chioma Ezinne, Chimed-Ochir, Odgerel, Chisumpa, Vesper Hichilombwe, Choi, Jee-Young Jasmine, Chowdhury, Rajiv, Christensen, Hanne, Christopher, Devasahayam Jesudas, Ciobanu, Liliana G, Cirillo, Massimo, Cohen, Aaron J, Colistro, Valentina, Colomar, Mercedes, Colquhoun, Samantha M, Cooper, Cyrus, Cooper, Leslie Trumbull, Cortinovis, Monica, Cowie, Benjamin C, Crump, John A, Damsere-Derry, James, Danawi, Hadi, Dandona, Rakhi, Daoud, Farah, Darby, Sarah C, Dargan, Paul I, das Neves, José, Davey, Gail, Davis, Adrian C, Davitoiu, Dragos V, de Castro, E Filipa, de Jager, Pieter, Leo, Diego De, Degenhardt, Louisa, Dellavalle, Robert P, Deribe, Kebede, Deribew, Amare, Dharmaratne, Samath D, Dhillon, Preet K, Diaz-Torné, Cesar, Ding, Eric L, dos Santos, Kadine Priscila Bender, Dossou, Edem, Driscoll, Tim R, Duan, Leilei, Dubey, Manisha, Duncan, Bruce Bartholow, Ellenbogen, Richard G, Ellingsen, Christian Lycke, Elyazar, Iqbal, Endries, Aman Yesuf, Ermakov, Sergey Petrovich, Eshrati, Babak, Esteghamati, Alireza, Estep, Kara, Faghmous, Imad D A, Fahimi, Saman, Faraon, Emerito Jose Aquino, Farid, Talha A, Farinha, Carla Sofia e Sa, Faro, André, Farvid, Maryam S, Farzadfar, Farshad, Feigin, Valery L, Fereshtehnejad, Seyed-Mohammad, Fernandes, Jefferson G, Fernandes, Joao C, Fischer, Florian, Fitchett, Joseph R A, Flaxman, Abraham, Foigt, Nataliya, Fowkes, F Gerry R, Franca, Elisabeth Barboza, Franklin, Richard C, Friedman, Joseph, Frostad, Joseph, Fürst, Thomas, Futran, Neal D, Gall, Seana L, Gambashidze, Ketevan, Gamkrelidze, Amiran, Ganguly, Parthasarathi, Gankpé, Fortuné Gbètoho, Gebre, Teshome, Gebrehiwot, Tsegaye Tsewelde, Gebremedhin, Amanuel Tesfay, Gebru, Alemseged Aregay, Geleijnse, Johanna M, Gessner, Bradford D, Ghoshal, Aloke Gopal, Gibney, Katherine B, Gillum, Richard F, Gilmour, Stuart, Giref, Ababi Zergaw, Giroud, Maurice, Gishu, Melkamu Dedefo, Giussani, Giorgia, Glaser, Elizabeth, Godwin, William W, Gomez-Dantes, Hector, Gona, Philimon, Goodridge, Amador, Gopalani, Sameer Vali, Gosselin, Richard A, Gotay, Carolyn C, Goto, Atsushi, Gouda, Hebe N, Greaves, Felix, Gugnani, Harish Chander, Gupta, Rahul, Gupta, Rajeev, Gupta, Vipin, Gutiérrez, Reyna A, Hafezi-Nejad, Nima, Haile, Demewoz, Hailu, Alemayehu Desalegne, Hailu, Gessessew Bugssa, Halasa, Yara A, Hamadeh, Randah Ribhi, Hamidi, Samer, Hancock, Jamie, Handal, Alexis J, Hankey, Graeme J, Hao, Yuantao, Harb, Hilda L, Harikrishnan, Sivadasanpillai, Haro, Josep Maria, Havmoeller, Rasmus, Heckbert, Susan R, Heredia-Pi, Ileana Beatriz, Heydarpour, Pouria, Hilderink, Henk B M, Hoek, Hans W, Hogg, Robert S, Horino, Masako, Horita, Nobuyuki, Hosgood, H Dean, Hotez, Peter J, Hoy, Damian G, Hsairi, Mohamed, Htet, Aung Soe, Htike, Maung Maung Than, Hu, Guoqing, Huang, Cheng, Huang, Hsiang, Huiart, Laetitia, Husseini, Abdullatif, Huybrechts, Inge, Huynh, Grace, Iburg, Kim Moesgaard, Innos, Kaire, Inoue, Manami, Iyer, Veena J, Jacobs, Troy A, Jacobsen, Kathryn H, Jahanmehr, Nader, Jakovljevic, Mihajlo B, James, Peter, Javanbakht, Mehdi, Jayaraman, Sudha P, Jayatilleke, Achala Upendra, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jiang, Ying, Jibat, Tariku, Jimenez-Corona, Aida, Jonas, Jost B, Joshi, Tushar Kant, Kabir, Zubair, Kamal, Ritul, Kan, Haidong, Kant, Surya, Karch, André, Karema, Corine Kakizi, Karimkhani, Chante, Karletsos, Dimitris, Karthikeyan, Ganesan, Kasaeian, Amir, Katibeh, Marzieh, Kaul, Anil, Kawakami, Norito, Kayibanda, Jeanne Françoise, Keiyoro, Peter Njenga, Kemmer, Laura, Kemp, Andrew Haddon, Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Kesavachandran, Chandrasekharan Nair, Khader, Yousef Saleh, Khalil, Ibrahim A, Khan, Abdur Rahman, Khan, Ejaz Ahmad, Khang, Young-Ho, Khera, Sahil, Khoja, Tawfik Ahmed Muthafer, Kieling, Christian, Kim, Daniel, Kim, Yun Jin, Kissela, Brett M, Kissoon, Niranjan, Knibbs, Luke D, Knudsen, Ann Kristin, Kokubo, Yoshihiro, Kolte, Dhaval, Kopec, Jacek A, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Krog, Norun Hjertager, Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kudom, Andreas A, Kuipers, Ernst J, Kulkarni, Veena S, Kumar, G Anil, Kwan, Gene F, Lal, Aparna, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lallukka, Tea, Lam, Hilton, Lam, Jennifer O, Langan, Sinead M, Lansingh, Van C, Larsson, Anders, Laryea, Dennis Odai, Latif, Asma Abdul, Lawrynowicz, Alicia Elena Beatriz, Leigh, James, Levi, Miriam, Li, Yongmei, Lindsay, M Patrice, Lipshultz, Steven E, Liu, Patrick Y, Liu, Shiwei, Liu, Yang, Lo, Loon-Tzian, Logroscino, Giancarlo, Lotufo, Paulo A, Lucas, Robyn M, Lunevicius, Raimundas, Lyons, Ronan A, Ma, Stefan, Machado, Vasco Manuel Pedro, Mackay, Mark T, MacLachlan, Jennifer H, Razek, Hassan Magdy Abd El, Magdy, Mohammed, Razek, Abd El, Majdan, Marek, Majeed, Azeem, Malekzadeh, Reza, Manamo, Wondimu Ayele Ayele, Mandisarisa, John, Mangalam, Srikanth, Mapoma, Chabila C, Marcenes, Wagner, Margolis, David Joel, Martin, Gerard Robert, Martinez-Raga, Jose, Marzan, Melvin Barrientos, Masiye, Felix, Mason-Jones, Amanda J, Massano, João, Matzopoulos, Richard, Mayosi, Bongani M, McGarvey, Stephen Theodore, McGrath, John J, McKee, Martin, McMahon, Brian J, Meaney, Peter A, Mehari, Alem, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Mekonnen, Alemayehu B, Melaku, Yohannes Adama, Memiah, Peter, Memish, Ziad A, Mendoza, Walter, Meretoja, Atte, Meretoja, Tuomo J, Mhimbira, Francis Apolinary, Micha, Renata, Millear, Anoushka, Miller, Ted R, Mirarefin, Mojde, Misganaw, Awoke, Mock, Charles N, Mohammad, Karzan Abdulmuhsin, Mohammadi, Alireza, Mohammed, Shafiu, Mohan, Viswanathan, Mola, Glen Liddell D, Monasta, Lorenzo, Hernandez, Julio Cesar Montañez, Montero, Pablo, Montico, Marcella, Montine, Thomas J, Moradi-Lakeh, Maziar, Morawska, Lidia, Morgan, Katherine, Mori, Rintaro, Mozaffarian, Dariush, Mueller, Ulrich O, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Srinivas, Musa, Kamarul Imran, Nachega, Jean B, Nagel, Gabriele, Naidoo, Kovin S, Naik, Nitish, Naldi, Luigi, Nangia, Vinay, Nash, Denis, Nejjari, Chakib, Neupane, Subas, Newton, Charles R, Newton, John N, Ng, Marie, Ngalesoni, Frida Namnyak, de Dieu Ngirabega, Jean, Nguyen, Quyen Le, Nisar, Muhammad Imran, Pete, Patrick Martial Nkamedjie, Nomura, Marika, Norheim, Ole F, Norman, Paul E, Norrving, Bo, Nyakarahuka, Luke, Ogbo, Felix Akpojene, Ohkubo, Takayoshi, Ojelabi, Foluke Adetola, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Opio, John Nelson, Oren, Eyal, Ortiz, Alberto, Osman, Majdi, Ota, Erika, Ozdemir, Raziye, PA, Mahesh, Pain, Amanda, Pandian, Jeyaraj D, Pant, Puspa Raj, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Parry, Charles D, Parsaeian, Mahboubeh, Caicedo, Angel J Paternina, Patten, Scott B, Patton, George C, Paul, Vinod K, Pearce, Neil, Pedro, João Mário, Stokic, Ljiljana Pejin, Pereira, David M, Perico, Norberto, Pesudovs, Konrad, Petzold, Max, Phillips, Michael Robert, Piel, Frédéric B, Pillay, Julian David, Plass, Dietrich, Platts-Mills, James A, Polinder, Suzanne, Pope, C Arden, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Quame-Amaglo, Justice, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahman, Sajjad Ur, Rai, Rajesh Kumar, Rajavi, Zhale, Rajsic, Sasa, Raju, Murugesan, Rakovac, Ivo, Rana, Saleem M, Ranabhat, Chhabi L, Rangaswamy, Thara, Rao, Puja, Rao, Sowmya R, Refaat, Amany H, Rehm, Jürgen, Reitsma, Marissa B, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Ricci, Stefano, Blancas, Maria Jesus Rios, Roberts, Bayard, Roca, Anna, Rojas-Rueda, David, Ronfani, Luca, Roshandel, Gholamreza, Rothenbacher, Dietrich, Roy, Ambuj, Roy, Nawal K, Ruhago, George Mugambage, Sagar, Rajesh, Saha, Sukanta, Sahathevan, Ramesh, Saleh, Muhammad Muhammad, Sanabria, Juan R, Sanchez-Niño, Maria Dolores, Sanchez-Riera, Lidia, Santos, Itamar S, Sarmiento-Suarez, Rodrigo, Sartorius, Benn, Satpathy, Maheswar, Savic, Miloje, Sawhney, Monika, Schaub, Michael P, Schmidt, Maria Inês, Schneider, Ione J C, Schöttker, Ben, Schutte, Aletta E, Schwebel, David C, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Shackelford, Katya A, Shaddick, Gavin, Shaheen, Amira, Shahraz, Saeid, Shaikh, Masood Ali, Shakh-Nazarova, Marina, Sharma, Rajesh, She, Jun, Sheikhbahaei, Sara, Shen, Jiabin, Shen, Ziyan, Shepard, Donald S, Sheth, Kevin N, Shetty, Balakrishna P, Shi, Peilin, Shibuya, Kenji, Shin, Min-Jeong, Shiri, Rahman, Shiue, Ivy, Shrime, Mark G, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Diego Augusto Santos, Silveira, Dayane Gabriele Alves, Silverberg, Jonathan I, Simard, Edgar P, Singh, Abhishek, Singh, Gitanjali M, Singh, Jasvinder A, Singh, Om Prakash, Singh, Prashant Kumar, Singh, Virendra, Soneji, Samir, Søreide, Kjetil, Soriano, Joan B, Sposato, Luciano A, Sreeramareddy, Chandrashekhar T, Stathopoulou, Vasiliki, Stein, Dan J, Stein, Murray B, Stranges, Saverio, Stroumpoulis, Konstantinos, Sunguya, Bruno F, Sur, Patrick, Swaminathan, Soumya, Sykes, Bryan L, Szoeke, Cassandra E I, Tabarés-Seisdedos, Rafael, Tabb, Karen M, Takahashi, Ken, Takala, Jukka S, Talongwa, Roberto Tchio, Tandon, Nikhil, Tavakkoli, Mohammad, Taye, Bineyam, Taylor, Hugh R, Ao, Braden J Te, Tedla, Bemnet Amare, Tefera, Worku Mekonnen, Have, Margreet Ten, Terkawi, Abdullah Sulieman, Tesfay, Fisaha Haile, Tessema, Gizachew Assefa, Thomson, Alan J, Thorne-Lyman, Andrew L, Thrift, Amanda G, Thurston, George D, Tillmann, Taavi, Tirschwell, David L, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Fotis, Towbin, Jeffrey Allen, Traebert, Jefferson, Tran, Bach Xuan, Truelsen, Thomas, Trujillo, Ulises, Tura, Abera Kenay, Tuzcu, Emin Murat, Uchendu, Uche S, Ukwaja, Kingsley N, Undurraga, Eduardo A, Uthman, Olalekan A, Dingenen, Rita Van, van Donkelaar, Aaron, Vasankari, Tommi, Vasconcelos, Ana Maria Nogales, Venketasubramanian, Narayanaswamy, Vidavalur, Ramesh, Vijayakumar, Lakshmi, Villalpando, Salvador, Violante, Francesco S, Vlassov, Vasiliy Victorovich, Wagner, Joseph A, Wagner, Gregory R, Wallin, Mitchell T, Wang, Linhong, Watkins, David A, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Werdecker, Andrea, Westerman, Ronny, White, Richard A, Wijeratne, Tissa, Wilkinson, James D, Williams, Hywel C, Wiysonge, Charles Shey, Woldeyohannes, Solomon Meseret, Wolfe, Charles D A, Won, Sungho, Wong, John Q, Woolf, Anthony D, Xavier, Denis, Xiao, Qingyang, Xu, Gelin, Yakob, Bereket, Yalew, Ayalnesh Zemene, Yan, Lijing L, Yano, Yuichiro, Yaseri, Mehdi, Ye, Pengpeng, Yebyo, Henock Gebremedhin, Yip, Paul, Yirsaw, Biruck Desalegn, Yonemoto, Naohiro, Yonga, Gerald, Younis, Mustafa Z, Yu, Shicheng, Zaidi, Zoubida, Zaki, Maysaa El Sayed, Zannad, Faiez, Zavala, Diego E, Zeeb, Hajo, Zeleke, Berihun M, Zhang, Hao, Zodpey, Sanjay, Zonies, David, Zuhlke, Liesl Joanna, Vos, Theo, Lopez, Alan D, and Murray, Christopher J L

Published
2016
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15. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Murray, Christopher J L, Ortblad, Katrina F, Guinovart, Caterina, Lim, Stephen S, Wolock, Timothy M, Roberts, D Allen, Dansereau, Emily A, Graetz, Nicholas, Barber, Ryan M, Brown, Jonathan C, Wang, Haidong, Duber, Herbert C, Naghavi, Mohsen, Dicker, Daniel, Dandona, Lalit, Salomon, Joshua A, Heuton, Kyle R, Foreman, Kyle, Phillips, David E, Fleming, Thomas D, Flaxman, Abraham D, Phillips, Bryan K, Johnson, Elizabeth K, Coggeshall, Megan S, Abd-Allah, Foad, Abera, Semaw Ferede, Abraham, Jerry P, Abubakar, Ibrahim, Abu-Raddad, Laith J, Abu-Rmeileh, Niveen Me, Achoki, Tom, Adeyemo, Austine Olufemi, Adou, Arsène Kouablan, Adsuar, José C, Agardh, Emilie Elisabet, Akena, Dickens, Al Kahbouri, Mazin J, Alasfoor, Deena, Albittar, Mohammed I, Alcalá-Cerra, Gabriel, Alegretti, Miguel Angel, Alemu, Zewdie Aderaw, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, Francois, Allen, Peter J, Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amankwaa, Adansi A, Amare, Azmeraw T, Amini, Hassan, Ammar, Walid, Anderson, Benjamin O, Antonio, Carl Abelardo T, Anwari, Palwasha, Ärnlöv, Johan, Arsenijevic, Valentina S Arsic, Artaman, Ali, Asghar, Rana J, Assadi, Reza, Atkins, Lydia S, Badawi, Alaa, Balakrishnan, Kalpana, Banerjee, Amitava, Basu, Sanjay, Beardsley, Justin, Bekele, Tolesa, Bell, Michelle L, Bernabe, Eduardo, Beyene, Tariku Jibat, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A, Abdulhak, Aref Bin, Binagwaho, Agnes, Blore, Jed D, Basara, Berrak Bora, Bose, Dipan, Brainin, Michael, Breitborde, Nicholas, Castañeda-Orjuela, Carlos A, Catalá-López, Ferrán, Chadha, Vineet K, Chang, Jung-Chen, Chiang, Peggy Pei-Chia, Chuang, Ting-Wu, Colomar, Mercedes, Cooper, Leslie Trumbull, Cooper, Cyrus, Courville, Karen J, Cowie, Benjamin C, Criqui, Michael H, Dandona, Rakhi, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Deribe, Kebede, Des Jarlais, Don C, Dessalegn, Muluken, Dharmaratne, Samath D, Dilmen, Uğur, Ding, Eric L, Driscoll, Tim R, Durrani, Adnan M, Ellenbogen, Richard G, Ermakov, Sergey Petrovich, Esteghamati, Alireza, Faraon, Emerito Jose A, Farzadfar, Farshad, Fereshtehnejad, Seyed-Mohammad, Fijabi, Daniel Obadare, Forouzanfar, Mohammad H, Fra.Paleo, Urbano, Gaffikin, Lynne, Gamkrelidze, Amiran, Gankpé, Fortuné Gbètoho, Geleijnse, Johanna M, Gessner, Bradford D, Gibney, Katherine B, Ginawi, Ibrahim Abdelmageem Mohamed, Glaser, Elizabeth L, Gona, Philimon, Goto, Atsushi, Gouda, Hebe N, Gugnani, Harish Chander, Gupta, Rajeev, Gupta, Rahul, Hafezi-Nejad, Nima, Hamadeh, Randah Ribhi, Hammami, Mouhanad, Hankey, Graeme J, Harb, Hilda L, Haro, Josep Maria, Havmoeller, Rasmus, Hay, Simon I, Hedayati, Mohammad T, Pi, Ileana B Heredia, Hoek, Hans W, Hornberger, John C, Hosgood, H Dean, Hotez, Peter J, Hoy, Damian G, Huang, John J, Iburg, Kim M, Idrisov, Bulat T, Innos, Kaire, Jacobsen, Kathryn H, Jeemon, Panniyammakal, Jensen, Paul N, Jha, Vivekanand, Jiang, Guohong, Jonas, Jost B, Juel, Knud, Kan, Haidong, Kankindi, Ida, Karam, Nadim E, Karch, André, Karema, Corine Kakizi, Kaul, Anil, Kawakami, Norito, Kazi, Dhruv S, Kemp, Andrew H, Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Khader, Yousef Saleh, Khalifa, Shams Eldin Ali Hassan, Khan, Ejaz Ahmed, Khang, Young-Ho, Khonelidze, Irma, Kinfu, Yohannes, Kinge, Jonas M, Knibbs, Luke, Kokubo, Yoshihiro, Kosen, S, Defo, Barthelemy Kuate, Kulkarni, Veena S, Kulkarni, Chanda, Kumar, Kaushalendra, Kumar, Ravi B, Kumar, G Anil, Kwan, Gene F, Lai, Taavi, Balaji, Arjun Lakshmana, Lam, Hilton, Lan, Qing, Lansingh, Van C, Larson, Heidi J, Larsson, Anders, Lee, Jong-Tae, Leigh, James, Leinsalu, Mall, Leung, Ricky, Li, Yichong, Li, Yongmei, De Lima, Graça Maria Ferreira, Lin, Hsien-Ho, Lipshultz, Steven E, Liu, Shiwei, Liu, Yang, Lloyd, Belinda K, Lotufo, Paulo A, Machado, Vasco Manuel Pedro, Maclachlan, Jennifer H, Magis-Rodriguez, Carlos, Majdan, Marek, Mapoma, Christopher Chabila, Marcenes, Wagner, Marzan, Melvin Barrientos, Masci, Joseph R, Mashal, Mohammad Taufiq, Mason-Jones, Amanda J, Mayosi, Bongani M, Mazorodze, Tasara T, Mckay, Abigail Cecilia, Meaney, Peter A, Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Melaku, Yohannes Adama, Memish, Ziad A, Mendoza, Walter, Miller, Ted R, Mills, Edward J, Mohammad, Karzan Abdulmuhsin, Mokdad, Ali H, Mola, Glen Liddell, Monasta, Lorenzo, Montico, Marcella, Moore, Ami R, Mori, Rintaro, Moturi, Wilkister Nyaora, Mukaigawara, Mitsuru, Murthy, Kinnari S, Naheed, Aliya, Naidoo, Kovin S, Naldi, Luigi, Nangia, Vinay, Narayan, K M Venkat, Nash, Denis, Nejjari, Chakib, Nelson, Robert G, Neupane, Sudan Prasad, Newton, Charles R, Ng, Marie, Nisar, Muhammad Imran, Nolte, Sandra, Norheim, Ole F, Nowaseb, Vincent, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Olusanya, Bolajoko O, Omer, Saad B, Opio, John Nelson, Orisakwe, Orish Ebere, Pandian, Jeyaraj D, Papachristou, Christina, Caicedo, Angel J Paternina, Patten, Scott B, Paul, Vinod K, Pavlin, Boris Igor, Pearce, Neil, Pereira, David M, Pervaiz, Aslam, Pesudovs, Konrad, Petzold, Max, Pourmalek, Farshad, Qato, Dima, Quezada, Amado D, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Sajjad Ur, Raju, Murugesan, Rana, Saleem M, Razavi, Homie, Reilly, Robert Quentin, Remuzzi, Giuseppe, Richardus, Jan Hendrik, Ronfani, Luca, Roy, Nobhojit, Sabin, Nsanzimana, Saeedi, Mohammad Yahya, Sahraian, Mohammad Ali, Samonte, Genesis May J, Sawhney, Monika, Schneider, Ione J C, Schwebel, David C, Seedat, Soraya, Sepanlou, Sadaf G, Servan-Mori, Edson E, Sheikhbahaei, Sara, Shibuya, Kenji, Shin, Hwashin Hyun, Shiue, Ivy, Shivakoti, Rupak, Sigfusdottir, Inga Dora, Silberberg, Donald H, Silva, Andrea P, Simard, Edgar P, Singh, Jasvinder A, Skirbekk, Vegard, Sliwa, Karen, Soneji, Samir, Soshnikov, Sergey S, Sreeramareddy, Chandrashekhar T, Stathopoulou, Vasiliki Kalliopi, Stroumpoulis, Konstantinos, Swaminathan, Soumya, Sykes, Bryan L, Tabb, Karen M, Talongwa, Roberto Tchio, Tenkorang, Eric Yeboah, Terkawi, Abdullah Sulieman, Thomson, Alan J, Thorne-Lyman, Andrew L, Towbin, Jeffrey A, Traebert, Jefferson, Tran, Bach X, Dimbuene, Zacharie Tsala, Tsilimbaris, Miltiadis, Uchendu, Uche S, Ukwaja, Kingsley N, Uzun, Selen Begüm, Vallely, Andrew J, Vasankari, Tommi J, Venketasubramanian, N, Violante, Francesco S, Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Waller, Stephen, Wallin, Mitchell T, Wang, Linhong, Wang, XiaoRong, Wang, Yanping, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G, Westerman, Ronny, White, Richard A, Wilkinson, James D, Williams, Thomas Neil, Woldeyohannes, Solomon Meseret, Wong, John Q, Xu, Gelin, Yang, Yang C, Yano, Yuichiro, Yentur, Gokalp Kadri, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa, Yu, Chuanhua, Jin, Kim Yun, El Sayed Zaki, Maysaa, Zhao, Yong, Zheng, Yingfeng, Zhou, Maigeng, Zhu, Jun, Zou, Xiao Nong, Lopez, Alan D, and Vos, Theo

Published
2014
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21. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

Author

Roth, Gregory A., Collaborotors, G. B. D.Causes Death, Abate, Degu, Abate, Kalkidan Hassen, Abay, Solomon M., Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Load, Abdela, Jemal, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Haftom Temesgen, Abebe, Molla, Abebe, Zegeye, Abejie, Ayenew Negesse, Abera, Semaw F., Abil, Olifan Zewdie, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Adamu, Abdu A., Adebayo, Oladimeji, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adookunboh, Olatunii, Adhena, Beyene Meressa, Adib, Mina G., Admasie, Aniha, Afshin, Ashkan, Agarwal, Gina, Agesa, Karelia M., Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Melidi, Ahmed, Muktar Beshir, Ahmed, Sayent, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Fddine, Akbari, Mohammad Esmaeil, Akinyeniti, Rufus Olusola, Akseer, Nadia, Al-Aly, Ziyad, Al-Eyadhy, Ayman, Al-Raddadi, Rajaa M., Alandab, Fares, Alam, Khurshid, Alam, Tahiya, Alebel, Animut, Alene, Kefyalew Addis, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, Francois, Allebeck, Peter, Alonso, Jordi, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T., Aminde, Leopold N., Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampern, Anber, Nahla Hamed, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansari, Hossein, Aniha, Mustafa Geleto, Antonio, Carl Abelardo T., Anwari, Palwasha, Aremu, Olatunde, Arnlov, Johan, Arora, Amit, Arora, Monika, Artaman, Al, Aryal, Krishna K., Asayesh, Hamid, Asfaw, Ephremi Tsegay, Ataro, Zerihun, Atique, Suleman, Atre, Sachin R., Ausloos, Marcel, Avokpaho, Euripide F. G. A., Awasthi, Ashish, Quintattilla, Beatriz Paulina Ayala, Ayele, Yohanes, Ayer, Rakesh, Azzopardi, Peter S., Babazadeh, Arefeh, Bacha, Umar, Badali, Hamid, Badawi, Alaa, Bali, Ayele Geleto, Ballesteros, Katherine E., Banach, Maciej, Banerjee, Kajori, Bannick, Marlena S., Banoub, Joseph Adel Mattar, Barboza, Miguel A., Barker-Collo, Suzanne Lyu, Barnighausen, Till Winfried, Barquera, Simon, Barrero, Lope, Bassat, Quique, Base, Sanjay, Baune, Bernhard T., Baynes, Habtamu Wondifraw, Bazargan-Hejazi, Shahrzad, Beth, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Behzadifar, Mcysam, Bejot, Yannick, Bekele, Bayu Begashaw, Belacliew, Abate Bekele, Belay, Ezra, Belay, Yihalem Abebe, Bell, Michelle L., Bello, Aminu K., Bennett, Derrick A., Bensenor, Isabela M., Berman, Adam F., Bernabe, Eduardo, Bernstein, Robert S., Bertolacci, Gregory J., Beuran, Mircea, Beyranvand, Tina, Bhalla, Ashish, Bhattarai, Suraj, Bhaumik, Sounayadeeep, Bhutta, Zulfiqar A., Biadgo, Belete, Biehl, Molly H., Bijani, Ali, Bikbov, Boris, Bilano, Ver, Bililign, Nigus, Bin Sayeed, Muhammad Shandaat, Bisanzio, Donal, Biswas, Tuhin, Blacker, Brigitte F., Basara, Berrak Bora, Borschmann, Rohan, Bosetti, Cristina, Bozorgmehr, Kayvan, Brady, Oliver J., Brant, Luisa C., Brayne, Carol, Brazinova, Alexandra, Breitborde, Nicholas J. K., Brenner, Hermann, Briant, Paul Svitil, Britton, Gabrielle, Brugha, Traolach, Busse, Reinhard, Butt, Zahid A., Callender, Charlton S. K. H., Campos-Nonato, Ismael R., Rincon, Julio Cesar Canapuzano, Cano, Jorge, Car, Mate, Cardenas, Rosario, Carreras, Giulia, Carrero, Juan J., Carter, Austin, Carvalho, Felix, Castaneda-Orjuela, Carlos A., Rivas, Jacqueline Castillo, Castle, Chris D., Castro, Clara, Castro, Franz, Catala-Lopez, Ferran, Cerin, Ester, Chaiah, Yazan, Chang, Jung -Chen, Chanson, Fiona J., Chaturvedi, Pankaj, Chiang, Peggy Pei-Chia, Chimed-Ochir, Odgerel, Chisumpa, Vesper Hichilombwe, Chitheet, Abdulaal, Chowdhury, Rajiv, Christensen, Hanne, Christopher, Devasahayam J., Chiang, Sheng-Chia, Cicuttini, Flavia M., Ciobanu, Liliana G., Cirillo, Massimo, Cohen, Aaron J., Cooper, Leslie Trumbull, Cortesi, Paolo Angelo, Cortinovis, Monica, Cousin, Ewerton, Cowie, Benjamin C., Criqui, Michael H., Cromwell, Elizabeth A., Crowe, Christopher Stephen, Crump, John A., Cunningham, Matthew, Daba, Alemneh Kabeta, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Dang, Anh Kim, Dargan, Paul I., Daryani, Ahmad, Das, Siddharth K., Das Gupta, Rajat, Das Neves, Jose, Dasa, Tamirat Tesfaye, Dash, Aditya Prasad, Davis, Adrian C., Weaver, Nicole Davis, Davitoiu, Dragos Virgil, Davletov, Kairat, De La Hoz, Fernando Pio, De Neve, Jan-Walter, Degefa, Meaza Girma, Degenhardt, Louisa, Degfie, Tizta T., Deiparine, Selina, Demoz, Gebre Teklemariam, Demtsu, Baleen Betsu, Denova-Gutierrez, Edgar, Deribe, Kebede, Dervenis, Nikolaos, Jarlais, Don C. 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Jc, Ferrari, Aj, Feyissa, Gt, Foigt, Na, Foreman, Kj, Frank, Td, Fuller, Je, Fürst, T, Furtado, Jm, Futran, Nd, Garcia-Basteiro, Al, Garcia-Gordillo, Ma, Gardner, Wm, Gebre, Ak, Gebrehiwot, Tt, Gebremedhin, At, Gebremichael, Tg, Gelano, Tf, Geleijnse, Jm, Geramo, Ycd, Gething, Pw, Gezae, Ke, Ghadami, Mr, Gibney, Kb, Gill, Tk, Gillum, Rf, Ginawi, Ia, Goldberg, Em, Gómez-Dantés, H, Gona, Pn, Gopalani, Sv, Gorman, Tm, Goulart, Ac, Gnedovskaya, Ev, Gugnani, Hc, Guimaraes, Al, Gupta, Pc, Gutiérrez, Ra, Haagsma, Ja, Hagos, Tb, Hailegiyorgis, Tt, Hailu, Gb, Hamadeh, Rr, Handal, Aj, Hankey, Gj, Harb, Hl, Haro, Jm, Hassen, Hy, Hay, Rj, Hay, Si, Hegazy, Mi, Henry, Nj, Hibstu, Dt, Hoek, Hw, Hole, Mk, Hosgood, Hd, Hosseini, Sm, Hotez, Pj, Hoy, Dg, Huang, Jj, Hussen, Mm, Irvani, Ssn, Irvine, Cm, Islam, Sm, Jacobsen, Kh, Jain, Sk, Jalu, Mt, James, Sl, Jayatilleke, Au, Jenkins, Kj, Jha, Rp, Johnson, Co, Johnson, Sc, Jonas, Jb, Jozwiak, Jj, Jungari, Sb, Jürisson, M, Kassa, Dh, Kassa, Gm, Kassa, Td, Kassebaum, Nj, Katikireddi, Sv, Karyani, Ak, Kefale, At, Keiyoro, Pn, Kemp, Gr, Kengne, Ap, Kesavachandran, Cn, Khafaie, Ma, Khalil, Ia, Khan, Ea, Khan, Ma, Khang, Yh, Khater, Mm, Khoja, At, Khosravi, Mh, Kiadaliri, Aa, Kibret, Gd, Kidanemariam, Zt, Kiirithio, Dn, Kim, Ye, Kim, Yj, Kimokoti, Rw, Kivimäki, M, Knudsen, Ak, Kocarnik, Jm, Kopec, Ja, Koul, Pa, Kravchenko, Ma, Kumar, Ga, Kutz, Mj, Kyu, Hh, Lad, Dp, Lad, Sd, Lal, Dk, Lam, Jo, Lami, Fh, Lansingh, Vc, Larson, Hj, Lau, Km, Lazarus, Jv, Lee, Ph, Leshargie, Ct, Lim, Ll, Limenih, Ma, Lopez, Ad, Lotufo, Pa, Macarayan, Erk, Mackay, Mt, Maclachlan, Jh, Maddison, Er, Maghavani, Dp, Malta, Dc, Manda, Al, Mandarano-Filho, Lg, Mansournia, Ma, Mapoma, Cc, Maravilla, Jc, Marks, Gb, Martins-Melo, Fr, März, W, Marzan, Mb, Masci, Jr, Massenburg, Bb, Mathur, Mr, Maulik, Pk, Mcgrath, Jj, Mcmahon, Bj, Mehndiratta, Mm, Mehta, Km, Mekonnen, Tc, Memiah, Ptn, Memish, Za, Mengistu, Dt, Mensah, Ga, Mereta, St, Meretoja, Tj, Mezgebe, Hb, Millear, Ai, Miller, Tr, Miller-Petrie, Mk, Mini, Gk, Mirrakhimov, Em, Misganaw, At, Mohammad, Ka, Mohammed, Ma, Mokdad, Ah, Moreno Velásquez, I, Morrison, Sd, Moschos, Mm, Mousavi, Sm, Muchie, Kf, Mueller, Uo, Mumford, Je, Musa, Ki, Nachega, Jb, Nansseu, Jr, Nascimento, Br, Negoi, Ri, Newton, Crj, Ngalesoni, Fn, Ngunjiri, Jw, Nguyen, Aq, Nguyen, Ht, Nguyen, Lh, Nguyen, Th, Ningrum, Dna, Nirayo, Yl, Nixon, Mr, Norheim, Of, Noubiap, Jj, Nouri, Hr, Nourollahpour Shiadeh, M, Nowroozi, Mr, Odell, Cm, Ogbo, Fa, Oh, Ih, Olagunju, At, Olivares, Pr, Olsen, He, Olusanya, Bo, Olusanya, Jo, Ong, Kl, Ong, Sk, Orpana, Hm, Ortiz, Jr, Øverland, S, Owolabi, Mo, Özdemir, R, P A, M, Pakhare, Ap, Pakpour, Ah, Pandian, Jd, Park, Ek, Parry, Cdh, Patton, Gc, Paturi, Vr, Paulson, Kr, Pereira, Dm, Phillips, Mr, Piel, Fb, Pigott, Dm, Pillay, Jd, Postma, Mj, Purcell, Ca, Quistberg, Da, Rade, Kw, Radfar, A, Rafay, A, Rafiei, A, Rahim, F, Rahman, Mhu, Rahman, Ma, Rai, Rk, Ranabhat, Cl, Rao, Pc, Rawaf, Dl, Razo-García, C, Reiner, Rc, Reitsma, Mb, Renzaho, Amn, Riahi, Sm, Ribeiro, Alp, Rios-Blancas, Mj, Roba, Kt, Roberts, Nl, Robinson, Sr, Sahraian, Ma, Saldanha, Rf, Sambala, Ez, Samy, Am, Sanchez-Niño, Md, Santomauro, Df, Santos, Jv, Milicevic, Mm, Sao Jose, Bp, Sarker, Ar, Sarmiento-Suárez, R, Sawant, Ar, Schmidt, Mi, Schneider, Ijc, Schöttker, B, Schutte, Ae, Schwebel, Dc, Scott, Jg, Sepanlou, Sg, Serván-Mori, E, Shackelford, Ka, Shaheen, Aa, Shaikh, Ma, Shrime, Mg, Siddiqi, Tj, Sigfusdottir, Id, Silberberg, Dh, Silva, Da, Silva, Jp, Silva, Ntd, Silveira, Dga, Singh, Ja, Singh, Np, Singh, Pk, Sinha, Dn, Sobaih, Bh, Sorensen, Rjd, Soriano, Jb, Soyiri, In, Sposato, La, Sreeramareddy, Ct, Stanaway, Jd, Starodubov, Vi, Stein, Dj, Stewart, Lg, Stokes, Ma, Subart, Ml, Sufiyan, Mb, Sur, Pj, Sykes, Bl, Sylaja, Pn, Sylte, Do, Szoeke, Cei, Tabarés-Seisdedos, R, Tadakamadla, Sk, Tassew, Sg, Tekalign, Tg, Tekle, Mg, Temsah, Mh, Teshale, My, Tessema, Ga, Thankappan, Kr, Thrift, Ag, Thurston, Gd, To, Qg, Torre, Ae, Tortajada-Girbés, M, Tovani-Palone, Mr, Tran, Bx, Tran, Kb, Troeger, Ce, Truelsen, Tc, Truong, Nt, Tsadik, Ag, Tuzcu, Em, Ukwaja, Kn, Undurraga, Ea, Updike, Rl, Uthman, Oa, Uzun, Sb, Valdez, Pr, Vasankari, Tj, Vladimirov, Sk, Vollset, Se, Wagner, Gr, Wallin, Mt, Walson, Jl, Wang, Yp, Wassie, Mm, Weintraub, Rg, Weldegwergs, Kg, Werkneh, Aa, West, Te, Whiteford, Ha, Wilner, Lb, Wolfe, Cda, Wu, Yc, Wyper, Gma, Yahyazadeh Jabbari, Sh, Yan, Ll, Yasin, Yj, Yentür, Gk, Yimer, Em, Yirsaw, Bd, Yoon, Sj, Younis, Mz, Zaman, Sb, Zeleke, Aj, Zenebe, Zm, Zhang, Al, Zuhlke, Lj, and Murray, Cjl.

Subjects
Adult, Male, Adolescent, national age-sex-specific mortality, UNITED-STATES, Global Health, Socioeconomic Factor, Global Burden of Disease, GBD, causes of death, Young Adult, Age Distribution, Life Expectancy, General & Internal Medicine, Cause of Death, PUBLIC-HEALTH PROBLEM, mortality, 282 causes global burden of disease, Sex Distribution, Child, Aged, Aged, 80 and over, BARRIERS, DEMENTIA, Medicine (all), Infant, Newborn, Infant, 11 Medical And Health Sciences, Middle Aged, TRENDS, PREVENTION, PREVALENCE, ALZHEIMERS-DISEASE, INDIVIDUALS, 3121 General medicine, internal medicine and other clinical medicine, Child, Preschool, REGISTRATION, Female, Human medicine, Human
Abstract

Background Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD 2017 provides a comprehensive assessment of cause-specific mortality for 282 causes in 195 countries and territories from 1980 to 2017. Methods The causes of death database is composed of vital registration (VR), verbal autopsy (VA), registry, survey, police, and surveillance data. GBD 2017 added ten VA studies, 127 country-years of VR data, 502 cancer-registry country-years, and an additional surveillance country-year. Expansions of the GBD cause of death hierarchy resulted in 18 additional causes estimated for GBD 2017. Newly available data led to subnational estimates for five additional countries Ethiopia, Iran, New Zealand, Norway, and Russia. Deaths assigned International Classification of Diseases (ICD) codes for non-specific, implausible, or intermediate causes of death were reassigned to underlying causes by redistribution algorithms that were incorporated into uncertainty estimation. We used statistical modelling tools developed for GBD, including the Cause of Death Ensemble model (CODErn), to generate cause fractions and cause specific death rates for each location, year, age, and sex. Instead of using UN estimates as in previous versions, GBD 2017 independently estimated population size and fertility rate for all locations. Years of life lost (YLLs) were then calculated as the sum of each death multiplied by the standard life expectancy at each age. All rates reported here are age-standardised. Findings At the broadest grouping of causes of death (Level 1), non-communicable diseases (NC Ds) comprised the greatest fraction of deaths, contributing to 73.4% (95% uncertainty interval [UI] 72.5-74.1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional (CMNN) causes accounted for 186% (17.9-19.6), and injuries 8.0% (7.7-8.2). Total numbers of deaths from NCD causes increased from 2007 to 2017 by 22.7% (21.5-23.9), representing an additional 7.61 million (7. 20-8.01) deaths estimated in 2017 versus 2007. The death rate from NCDs decreased globally by 7.9% (7.08.8). The number of deaths for CMNN causes decreased by 222% (20.0-24.0) and the death rate by 31.8% (30.1-33.3). Total deaths from injuries increased by 2.3% (0-5-4-0) between 2007 and 2017, and the death rate from injuries decreased by 13.7% (12.2-15.1) to 57.9 deaths (55.9-59.2) per 100 000 in 2017. Deaths from substance use disorders also increased, rising from 284 000 deaths (268 000-289 000) globally in 2007 to 352 000 (334 000-363 000) in 2017. Between 2007 and 2017, total deaths from conflict and terrorism increased by 118.0% (88.8-148.6). A greater reduction in total deaths and death rates was observed for some CMNN causes among children younger than 5 years than for older adults, such as a 36.4% (32.2-40.6) reduction in deaths from lower respiratory infections for children younger than 5 years compared with a 33.6% (31.2-36.1) increase in adults older than 70 years. Globally, the number of deaths was greater for men than for women at most ages in 2017, except at ages older than 85 years. Trends in global YLLs reflect an epidemiological transition, with decreases in total YLLs from enteric infections, respirator}, infections and tuberculosis, and maternal and neonatal disorders between 1990 and 2017; these were generally greater in magnitude at the lowest levels of the Socio-demographic Index (SDI). At the same time, there were large increases in YLLs from neoplasms and cardiovascular diseases. YLL rates decreased across the five leading Level 2 causes in all SDI quintiles. The leading causes of YLLs in 1990 neonatal disorders, lower respiratory infections, and diarrhoeal diseases were ranked second, fourth, and fifth, in 2017. Meanwhile, estimated YLLs increased for ischaemic heart disease (ranked first in 2017) and stroke (ranked third), even though YLL rates decreased. Population growth contributed to increased total deaths across the 20 leading Level 2 causes of mortality between 2007 and 2017. Decreases in the cause-specific mortality rate reduced the effect of population growth for all but three causes: substance use disorders, neurological disorders, and skin and subcutaneous diseases. Interpretation Improvements in global health have been unevenly distributed among populations. Deaths due to injuries, substance use disorders, armed conflict and terrorism, neoplasms, and cardiovascular disease are expanding threats to global health. For causes of death such as lower respiratory and enteric infections, more rapid progress occurred for children than for the oldest adults, and there is continuing disparity in mortality rates by sex across age groups. Reductions in the death rate of some common diseases are themselves slowing or have ceased, primarily for NCDs, and the death rate for selected causes has increased in the past decade. Copyright (C) 2018 The Author(s). Published by Elsevier Ltd.

Published
2018

22. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019 : a systematic analysis for the Global Burden of Disease Study 2019

Author

Abbafati, Cristiana, Abbas, Kaja M., Abbasi, Mohammad, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abbastabar, Hedayat, Abd-Allah, Foad, Abdelalim, Ahmed, Abdollahi, Mohammad, Abdollahpour, Ibrahim, Abedi, Aidin, Abedi, Parisa, Abegaz, Kedir Hussein, Abolhassani, Hassan, Abosetugn, Akine Eshete, Aboyans, Victor, Abrams, Elissa M., Abreu, Lucas Guimaraes, Abrigo, Michael R. M., Abu Haimed, Abdulaziz Khalid, Abualhasan, Ahmed, Abu-Gharbieh, Eman, Abu-Raddad, Laith Jamal, Abushouk, Abdelrahman I., Acebedo, Alyssa, Ackerman, Ilana N., Adabi, Maryam, Adair, Tim, Adamu, Abdu A., Adebayo, Oladimeji M., Adedeji, Isaac Akinkunmi, Adekanmbi, Victor, Adelson, Jaimie D., Adeoye, Abiodun Moshood, Adetokunboh, Olatunji O., Adham, Davoud, Advani, Shailesh M., Afarideh, Mohsen, Afshari, Mahdi, Afshin, Ashkan, Agardh, Emilie E., Agarwal, Gina, Agasthi, Pradyumna, Agesa, Kareha M., Aghaali, Mohammad, Aghamir, Seyed Mohammad Kazem, Agrawal, Anurag, Ahmad, Tauseef, Ahmadi, Alireza, Ahmadi, Keivan, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmadpour, Ehsan, Ahmed, Muktar Beshir, Aji, Budi, Akalu, Temesgen Yihunie, Akinyemi, Rufus Olusola, Akinyemiju, Tomi, Akombi, Blessing, Akunna, Chisom Joyqueenet, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Samiah, Alam, Tahiya, Alanezi, Fahad Mashhour, Alanzi, Turki M., Albertson, Samuel B., Alcalde-Rabanal, Jacqueline Elizabeth, Alema, Niguse Meles, Alemu, Biresaw Wassihun, Alemu, Yihun Mulugeta, Alhabib, Khalid F., Alhassan, Robert Kaba, Ali, Muhammad, Ali, Saqib, Alicandro, Gianfranco, Alijanzadeh, Mehran, Alinia, Cyrus, Alipour, Vahid, Alizade, Hesam, Aljunid, Syed Mohamed, Alla, Francois, Allebeck, Peter, Almadi, Majid Abdulrahman Hamad, Almasi, Ali, Almasi-Hashiani, Amir, Almasri, Nihad A., Al-Mekhlafi, Hesham M., Almulhim, Abdulaziz M., Alonso, Jordi, Al-Raddadi, Rajaa M., Altirkawi, Khalid A., Alumran, Arwa Khalid, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J., Amare, Azmeraw T., Amare, Bekalu, Amini, Saeed, Amini-Rarani, Mostafa, Aminorroaya, Arya, Amiri, Fatemeh, Amit, Arianna Maever L., Amugsi, Dickson A., Amul, Gianna Gayle Herrera, Anbesu, Etsay Woldu, Ancuceanu, Robert, Anderlini, Deanna, Anderson, Jason A., Andrei, Catalina Liliana, Andrei, Tudorel, Androudi, Sofia, Angus, Colin, Anjomshoa, Mina, Ansari, Fereshteh, Ansari, Iman, Ansari-Moghaddam, Alireza, Antonazzo, Ippazio Cosimo, Antonio, Carl Abelardo T., Antony, Catherine M., Antriyandarti, Ernoiz, Anvari, Davood, Anwer, Razique, Appiah, Seth Christopher Yaw, Arabloo, Jalal, Arab-Zozani, Morteza, Aravkin, Aleksandr Y., Arba, Aseb Arba Kinfe, Aremu, Olatunde, Ariani, Filippo, Aripov, Timur, Armoon, Bahram, Arnlov, Johan, Arowosegbe, Oluwaseyi Olalekan, Aryal, Krishna K., Arzani, Afsaneh, Asaad, Malke, Asadi-Aliabadi, Mehran, Asadi-Pooya, Ali A., Asgari, Samaneh, Asghari, Babak, Jafarabadi, Mohammad Asghari, Ashbaugh, Charlie, Assmus, Michael, Atafar, Zahra, Athari, Seyyed Shamsadin, Atnafu, Desta Debalkie, Atout, Maha Moh'd Wahbi, Atre, Sachin R., Atteraya, Madhu Sudhan, Ausloos, Floriane, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel Gbenato Arthur, Quintanilla, Beatriz Paulina Ayala, Ayano, Getinet, Ayanore, Martin Amogre, Aynalem, Getie Lake, Aynalem, Yared Asmare, Ayza, Muluken Altaye, Azari, Samad, Azarian, Ghasem, Azene, Zelalem Nigussie, Azhar, Gulrez, Azzopardi, Peter S., Darshan, B. B., Babaee, Ebrahim, Badawi, Alaa, Badiye, Ashish D., Bagherzadeh, Mojtaba, Bagli, Eleni, Bahrami, Mohammad Amin, Baig, Atif Amin, Bairwa, Mohan, Bakhshaei, Mohammad Hossein, Bakhtiari, Ahad, Bakkannavar, Shankar M., Balachandran, Arun, Balakrishnan, Senthilkumar, Balalla, Shivanthi, Balassyano, Shelly, Baldasseroni, Alberto, Ball, Kylie, Ballew, Shoshana H., Balzi, Daniela, Banach, Maciej, Banerjee, Srikanta K., Banik, Palash Chandra, Bannick, Marlena S., Bante, Agegnehu Bante, Bante, Simachew Animen, Baraki, Adhanom Gebreegziabher, Barboza, Miguel A., Barker-Collo, Suzanne Lyn, Barnighausen, Till Winfried, Barrero, Lope H., Barthelemy, Celine M., Barua, Lingkan, Barzegar, Akbar, Basaleem, Huda, Bassat, Quique, Basu, Sanjay, Baune, Bernhard T., Bayati, Mohsen, Baye, Bayisa Abdissa, Bazmandegan, Gholamreza, Becker, Jacob S., Bedi, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Bejot, Yannick, Bekuma, Tariku Tesfaye Tesfaye, Bell, Michelle L., Bello, Aminu K., Bender, Rose G., Bennett, Derrick A., Bennitt, Fiona B., Bensenor, Isabela M., Benziger, Catherine P., Berhe, Kidanemaryam, Berman, Adam E., Bernabe, Eduardo, Bernstein, Robert S., Bertolacci, Gregory J., Bhagavathula, Akshaya Srikanth, Bhageerathy, Reshmi, Bhala, Neeraj, Bhandari, Dinesh, Bhardwaj, Pankaj, Bhat, Anusha Ganapati, Bhattacharyya, Krittika, Bhattarai, Suraj, Bhutta, Zulfiqar A., Bibi, Sadia, Biehl, Molly H., Bijani, Ali, Bikbov, Boris, Bilano, Ver, Bin Sayeed, Muhammad Shahdaat, Biondi, Antonio, Birihane, Binyam Minuye, Bisanzio, Donal, Bisignano, Catherine, Biswas, Raaj Kishore, Bitew, Helen, Bjorge, Tone, Bockarie, Moses John, Bohlouli, Somayeh, Bohluli, Mehdi, Bojia, Hunduma Amensisa, Bolla, Srinivasa Rao, Boloor, Archith, Boon-Dooley, Alexandra S., Borges, Guilherme, Borzi, Antonio Maria, Borzouei, Shiva, Bose, Dipan, Bosetti, Cristina, Boufous, Soufiane, Bourne, Rupert, Brady, Oliver J., Braithwaite, Dejana, Brauer, Michael, Brayne, Carol, Breitborde, Nicholas J. K., Breitner, Susanne, Brenner, Hermann, Breusov, Alexey V., Briant, Paul Svitil, Briggs, Andrew M., Briko, Andrey Nikolaevich, Briko, Nikolay Ivanovich, Britton, Gabrielle B., Brugha, Traolach, Bryazka, Dana, Buchbinder, Rachelle, Bumgarner, Blair R., Burkart, Katrin, Burnett, Richard Thomas, Nagaraja, Sharath Burugina, Busse, Reinhard, Butt, Zahid A., Caetano dos Santos, Florentino Luciano, Cahill, Leah E., Cahuana-Hurtado, Lucero, Cai, Tianji, Callender, Charlton S. K. H., Camera, Luis Alberto, Campos-Nonato, Ismael R., Rincon, Julio Cesar Campuzano, Cao, Jackie, Car, Josip, Cardenas, Rosario, Carreras, Giulia, Carrero, Juan J., Carvalho, Felix, Castaldelli-Maia, Joao Mauricio, Castaneda-Orjuela, Carlos A., Castelpietra, Giulio, Castle, Chris D., Castro, Emma, Castro, Franz, Catala-Lopez, Ferran, Causey, Kate, Cederroth, Christopher R., Cercy, Kelly M., Cerin, Ester, Chalek, Julian, Chandan, Joht Singh, Chang, Alex R., Chang, Angela Y., Chang, Jung-Chen, Chang, Kai-Lan, Charan, Jaykaran, Charlson, Fiona J., Chattu, Vijay Kumar, Chaturvedi, Sarika, Cherbuin, Nicolas, Chimed-Ochir, Odgerel, Chin, Ken Lee, Chirinos-Caceres, Jesus Lorenzo, Cho, Daniel Youngwhan, Choi, Jee-Young Jasmine, Christensen, Hanne, Chu, Dinh-Toi, Chung, Michael T., Chung, Sheng-Chia, Cicuttini, Flavia M., Ciobanu, Liliana G., Cirillo, Massimo, Cislaghi, Beniamino, Classen, Thomas Khaled Dwayne, Cohen, Aaron J., Collins, Emma L., Comfort, Haley, Compton, Kelly, Conti, Sara, Cooper, Owen R., Corso, Barbara, Cortesi, Paolo Angelo, Costa, Vera Marisa, Cousin, Ewerton, Cowden, Richard G., Cowie, Benjamin C., Cromwell, Elizabeth A., Croneberger, Andrew J., Cross, Di H., Cross, Marita, Crowe, Christopher Stephen, Cruz, Jessica A., Cummins, Steven, Cunningham, Matthew, Dahlawi, Saad M. A., Dai, Haijiang, Dai, Hancheng, Damasceno, Albertino Antonio Moura, Damiani, Giovanni, D'Amico, Emanuele, Dandona, Lalit, Dandona, Rakhi, Daneshpajouhnejad, Parnaz, Dangel, William James, Danielsson, Anna-Karin, Gela, Jiregna Darega, Dargan, Paul I., Darwesh, Aso Mohammad, Daryani, Ahmad, Das, Jai K., Das Gupta, Rajat, Das Neves, Jose, Dash, Aditya Prasad, Davey, Gail, Davila-Cervantes, Claudio Alberto, Davis, Adrian C., Davitoiu, Dragos Virgil, Davletov, Kairat, De Leo, Diego, De Neve, Jan-Walter, Dean, Frances E., DeCleene, Nicole K., Deen, Amanda, Degenhardt, Louisa, DeLang, Marissa, Dellavalle, Robert Paul, Demeke, Feleke Mekonnen, Demoz, Gebre Teklemariam, Demsie, Desalegn Getnet, Denova-Gutierrez, Edgar, Dereje, Nebiyu Dereje, Deribe, Kebede, Dervenis, Nikolaos, Desai, Rupak, Desalew, Assefa, Dessie, Getenet Ayalew, Deuba, Keshab, Dharmaratne, Samath Dhamminda, Dhungana, Govinda Prasad, Dianatinasab, Mostafa, da Silva, Diana Dias, Diaz, Daniel, Forooshani, Zahra Sadat Dibaji, Dichgans, Martin, Didarloo, Alireza, Dingels, Zachary V., Dippenaar, Ilse N., Dirac, M. Ashworth, Djalalinia, Shirin, Do, Hoa Thi, Dokova, Klara, Doku, David Teye, Dolecek, Christiane, Dolgert, Andrew J., Dorostkar, Fariba, Doshi, Chirag P., Doshi, Pratik P., Doshmangir, Leila, Douiri, Abdel, Doxey, Matthew C., Doyle, Kerrie E., Driscoll, Tim Robert, Dubljanin, Eleonora, Dunachie, Susanna J., Duncan, Bruce B., Duraes, Andre Rodrigues, Eagan, Arielle Wilder, Ebrahimi, Hedyeh, Kalan, Mohammad Ebrahimi, Edvardsson, David, Effiong, Andem, Ehrlich, Joshua R., El Nahas, Nevine, El Sayed, Iman, Zaki, Maysaa El Sayed, El Tantawi, Maha, Elbarazi, Iffat, Elgendy, Islam Y., Elhabashy, Hala Rashad, El-Jaafary, Shaimaa I., Elsharkawy, Aisha, Elyazar, Iqbal R. 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F., Emamian, Mohammad Hassan, Emmons-Bell, Sophia, Erskine, Holly E., Eshrati, Babak, Eskandari, Khalil, Eskandarieh, Sharareh, Esmaeilnejad, Saman, Esmaeilzadeh, Firooz, Esteghamati, Alireza, Esteghamati, Sadaf, Estep, Kara, Etemadi, Arash, Etisso, Atkilt Esaiyas, Ezekannagha, Oluchi, Fanzo, Jessica, Farag, Tamer, Farahmand, Mohammad, Faraj, Anwar, Faraon, Emerito Jose A., Fareed, Mohammad, Faridnia, Roghiyeh, Farinha, Carla Sofia e Sa, Farioli, Andrea, Faris, Pawan Sirwan, Faro, Andre, Faruque, Mithila, Farzadfar, Farshad, Fattahi, Nazir, Fazaeli, Ali Akbar, Fazlzadeh, Mehdi, Feigin, Valery L., Feldman, Rachel, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Ferrara, Giannina, Ferrara, Pietro, Ferrari, Alize J., Ferreira, Manuela L., Feyissa, Garumma Tolu, Filip, Irina, Fischer, Florian, Fisher, James L., Fitzgerald, Ryan, Flohr, Carsten, Flor, Luisa Sorio, Foigt, Nataliya A., Folayan, Morenike Oluwatoyin, Fomenkov, Artem Alekseevich, Force, Lisa M., Fornari, Carla, Foroutan, Masoud, Fox, Jack T., Francis, Joel Msafiri, Frank, Tahvi D., Franklin, Richard Charles, Freitas, Marisa, Fu, Weijia, Fukumoto, Takeshi, Fukutaki, Kai, Fuller, John E., Fullman, Nancy, Furtado, Joao M., Gad, Mohamed M., Gaidhane, Abhay Motiramji, Gakidou, Emmanuela, Galles, Natalie C., Gallus, Silvano, Gamkrelidze, Amiran, Garcia-Basteiro, Alberto L., Gardner, William M., Geberemariyam, Biniyam Sahiledengle, Gebrehiwot, Abiyu Mekonnen, Gebremedhin, Ketema Bizuwork, Gebremeskel, Gebreamlak Gebremedhn, Gebremeskel, Leake G., Gebresillassie, Begashaw Melaku, Gebreslassie, Assefa Ayalew Ayalew Ayalew, Geramo, Yilma Chisha Dea, Geremew, Abraham, Hayoon, Anna Gershberg, Gesesew, Hailay Abrha, Gething, Peter W., Gezae, Kebede Embaye, Ghadimi, Maryam, Ghadiri, Keyghobad, Ghaffarifar, Fatemeh, Ghafourifard, Mansour, Ghajar, Alireza, Ghamari, Farhad, Ghashghaee, Ahmad, Ghiasvand, Hesam, Ghith, Nermin, Gholamian, Asadollah, Ghosh, Rakesh, Giampaoli, Simona, Gilani, Syed Amir, Gill, Paramjit Singh, Gill, Tiffany K., Gillum, Richard F., Ginawi, Ibrahim Abdelmageed, Ginindza, Themba G., Gitimoghaddam, Mojgan, Giussani, Giorgia, Glagn, Mustefa, Glushkova, Ekaterina Vladimirovna, Gnedovskaya, Elena V., Godinho, Myron Anthony, Goharinezhad, Salime, Golechha, Mahaveer, Goli, Srinivas, Gomez, Ricardo Santiago, Gona, Philimon N., Gopalani, Sameer Vali, Goren, Emily, Gorini, Giuseppe, Gorman, Taren M., Gottlich, Harrison Chase, Goudarzi, Houman, Goudarzian, Amir Hossein, Goulart, Alessandra C., Goulart, Barbara Niegia Garcia, Grada, Ayman, Greaves, Felix, Grivna, Michal, Grosso, Giuseppe, Gubari, Mohammed Ibrahim Mohialdeen, Gudi, Nachiket, Gugnani, Harish Chander, Guimaraes, Andre Luiz Sena, Guimaraes, Rafael Alves, Guled, Rashid Abdi, Gultie, Teklemariam, Guo, Gaorui, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Sharan, Subodh, Gupta, Tarun, Haagsma, Juanita A., Hachinski, Vladimir, Haddock, Beatrix, Hafezi-Nejad, Nima, Hafiz, Abdul, Hagins, Hailey, Haile, Lydia M., Haile, Teklehaimanot Gereziher, Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Hall, Brian J., Halvaei, Iman, Hamadeh, Randah R., Abdullah, Kanaan Hamagharib, Hameed, Sajid, Hamidi, Samer, Hamilton, Erin B., Hammer, Melanie S., Han, Chieh, Han, Hannah, Handiso, Demelash Woldeyohannes, Hanif, Asif, Hankey, Graeme J., Haririan, Hamidreza, Haro, Josep Maria, Harvey, James D., Hasaballah, Ahmed I., Hasan, Md Mehedi, Hasanpoor, Edris, Hasanzadeh, Amir, Hashemian, Maryam, Hashi, Abdiwahab, Hassan, Amr, Hassan, Shoaib, Hassanipour, Soheil, Hassankhani, Hadi, Havmoeller, Rasmus J., Hay, Roderick J., Hay, Simon I., Hayat, Khezar, Heibati, Behzad, Heidari, Behnam, Heidari, Golnaz, Heidari-Soureshjani, Reza, Hendrie, Delia, Henny, Kiana, Henok, Andualem, Henrikson, Hannah J., Henry, Nathaniel J., Herbert, Molly E., Herteliu, Claudiu, Heydarpour, Fatemeh, Hird, Thomas R., Ho, Hung Chak, Hoek, Hans W., Hole, Michael K., Holla, Ramesh, Hollingsworth, Bruce, Hoogar, Praveen, Hopf, Kathleen Pillsbury, Horita, Nobuyuki, Hosgood, H. Dean, Hossain, Naznin, Hosseini, Mostafa, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Hoy, Damian G., Hsairi, Mohamed, Hsiao, Thomas, Hsieh, Vivian Chia-Rong, Hu, Guoqing, Hu, Kejia, Huda, Tanvir M., Hugo, Fernando N., Humayun, Ayesha, Hussain, Rabia, Huynh, Chantal K., Hwang, Bing-Fang, Iannucci, Vincent C., Iavicoli, Ivo, Ibeneme, Charles Ugochukwu, Ibitoye, Segun Emmanuel, Ikeda, Nayu, Ikuta, Kevin S., Ilesanmi, Olayinka Stephen, Ilic, Irena M., Ilic, Milena D., Imani-Nasab, Mohammad Hasan, Inbaraj, Leeberk Raja, Ippolito, Helen, Iqbal, Usman, Irvani, Seyed Sina Naghibi, Irvine, Caleb Mackay Salpeter, Islam, M. Mofizul, Islam, MdMohaimenul, Islam, Sheikh Mohammed Shariful, Islami, Farhad, Iso, Hiroyasu, Ivers, Rebecca Q., Iwu, Chidozie C. 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Q., Kohler, Stefan, Kolola, Tufa, Komaki, Hamidreza, Kopec, Jacek A., Korotkova, Anna V., Korshunov, Vladimir Andreevich, Kosen, Soewarta, Kotlo, Anirudh, Koul, Parvaiz A., Koyanagi, Ai, Kraemer, Moritz U. G., Kravchenko, Michael A., Krishan, Kewal, Krohn, Kris J., Kromhout, Hans, Shaji, K. S., Defo, Barthelemy Kuate, Bicer, Burcu Kucuk, Kugbey, Nuworza, Kulkarni, Vaman, Kumar, G. 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N., Memish, Ziad A., Mendoza, Walter, Menezes, Ritesh G., Mengesha, Endalkachew Worku, Mengesha, Meresa Berwo, Mensah, George A., Mereke, Alibek, Mereta, Seid Tiku, Meretoja, Atte, Meretoja, Tuomo J., Mestrovic, Tomislav, Miazgowski, Bartosz, Miazgowski, Tomasz, Michalek, Irmina Maria, Mihretie, Kebadnew Mulatu, Miller, Ted R., Mills, Edward J., Milne, George J., Mini, G. K., Miri, Mohammad, Mirica, Andreea, Mirrakhimov, Erkin M., Mirzaei, Hamed, Mirzaei, Maryam, Mirzaei, Roya, Mirzaei-Alavijeh, Mehdi, Misganaw, Awoke Temesgen, Mitchell, Philip B., Mithra, Prasanna, Moazen, Babak, Moghadaszadeh, Masoud, Mohajer, Bahram, Mohamad, Osama, Mohamadi, Efat, Mohammad, Dara K., Mohammad, Yousef, Mezerji, Naser Mohammad Gholi, Mohammadbeigi, Abolfazl, Mohammadian-Hafshejani, Abdollah, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohammed, Ammas Siraj, Mohammed, Hussen, Mohammed, Jemal Abdu, Mohammed, Shafiu, Mohebi, Farnam, Bandpei, Mohammad A. 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H., Pasovic, Maja, Pasupula, Deepak Kumar, Patel, Jenil R., Patel, Sangram Kishor, Paternina-Caicedo, Angel J., Pathak, Ashish, Pathak, Mona, Patten, Scott B., Patton, George C., Paudel, Deepak, Paudel, Sagun, Paulson, Katherine R., Toroudi, Hamidreza Pazoki, Pease, Spencer A., Peden, Amy E., Pennini, Alyssa, Pepito, Veincent Christian Filipino, Peprah, Emmanuel K., Pereira, Alexandre, Pereira, David M., Pereira, Jeevan, Perico, Norberto, Pescarini, Julia Moreira, Pesudovs, Konrad, Pham, Hai Quang, Phillips, Michael R., Piccinelli, Cristiano, Pierce, Maxwell, Pigott, David M., Pilgrim, Thomas, Pilz, Tessa M., Pinheiro, Marina, Piradov, Michael A., Pirsaheb, Meghdad, Pishgar, Farhad, Plana-Ripoll, Oleguer, Plass, Dietrich, Pletcher, Martin, Pokhrel, Khem Narayan, Polibin, Roman V., Polinder, Suzanne, Polkinghorne, Kevan R., Pond, Constance Dimity, Postma, Maarten J., Pottoo, Faheem Hyder, Pourjafar, Hadi, Pourmalek, Farshad, Kalhori, Reza Pourmirza, Pourshams, Akram, Poznanska, Anna, Prada, Sergio I., Prakash, Sanjay, Prakash, V., Prasad, Narayan, Preotescu, Liliana, Pribadi, Dimas Ria Angga, Pupillo, Elisabetta, Quazi Syed, Zahiruddin, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Rafiee, Ata, Rafiei, Alireza, Raggi, Alberto, Rahim, Fakher, Rahimi-Movaghar, Afarin, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rajabpour-Sanati, Ali, Rajati, Fatemeh, Rakovac, Ivo, Ram, Pradhum, Ramezanzadeh, Kiana, Rana, Saleem Muhammad, Ranabhat, Chhabi Lal, Ranta, Annemarei, Rao, Puja C., Rao, Sowmya J., Rasella, Davide, Rashedi, Vahid, Rastogi, Prateek, Rath, Goura Kishor, Rathi, Priya, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Rawat, Ramu, Razo, Christian, Boston, Sofia, Regassa, Lemma Demissie, Reiner, Robert C., Jr., Reinig, Nickolas, Reitsma, Marissa Bettay, Remuzzi, Giuseppe, Renjith, Vishnu, Renzaho, Andre M. N., Resnikoff, Serge, Rezaei, Negar, Rezaei, Nima, Rezai, Mohammad Sadegh, Rezapour, Aziz, Rhinehart, Phoebe-Anne, Riahi, Seyed Mohammad, Ribeiro, Antonio Luiz P., Ribeiro, Daniel Cury, Ribeiro, Daniela, Rickard, Jennifer, Rivera, Juan A., Robalik, Toshana, Roberts, Nicholas L. S., Roberts, Shaun, Robinson, Stephen R., Rodriguez-Ramirez, Sonia, Roever, Leonardo, Rolfe, Sam, Romoli, Michele, Ronfani, Luca, Room, Robin, Roshandel, Gholamreza, Rostamian, Morteza, Roth, Gregory A., Rothenbacher, Dietrich, Rubagotti, Enrico, Rumisha, Susan Fred, Rwegerera, Godfrey M., Saadatagah, Seyedmohammad, Sabour, Siamak, Sachdev, Perminder S., Saddik, Basema, Sadeghi, Ehsan, Sadeghi, Masoumeh, Saeedi, Reza, Moghaddam, Sahar Saeedi, Saeidi, Shahram, Safari, Yahya, Safi, Sare, Safiri, Saeid, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, S. 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M., Zlavog, Bianca S., Zodpey, Sanjay, Lim, Stephen S., and Murray, Christopher J. L.

Abstract

In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the post

Published
2020
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23. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019:a systematic analysis for the Global Burden of Disease Study 2019

Author

Vos, Theo, Lim, Stephen S, Abbafati, Cristiana, Abbas, Kaja M, Abbasi, Mohammad, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abbastabar, Hedayat, Abd-Allah, Foad, Abdelalim, Ahmed, Abdollahi, Mohammad, Abdollahpour, Ibrahim, Abolhassani, Hassan, Aboyans, Victor, Abrams, Elissa M, Abreu, Lucas Guimarães, Abrigo, Michael R M, Abu-Raddad, Laith Jamal, Abushouk, Abdelrahman I, Acebedo, Alyssa, Ackerman, Ilana N, Adabi, Maryam, Adamu, Abdu A, Adebayo, Oladimeji M, Adekanmbi, Victor, Adelson, Jaimie D, Adetokunboh, Olatunji O, Adham, Davoud, Afshari, Mahdi, Afshin, Ashkan, Agardh, Emilie E, Agarwal, Gina, Agesa, Kareha M, Aghaali, Mohammad, Aghamir, Seyed Mohammad Kazem, Agrawal, Anurag, Ahmad, Tauseef, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmadpour, Ehsan, Akalu, Temesgen Yihunie, Akinyemi, Rufus Olusola, Akinyemiju, Tomi, Akombi, Blessing, Al-Aly, Ziyad, Alam, Khurshid, Alam, Noore, Alam, Samiah, Alam, Tahiya, Alanzi, Turki M, Albertson, Samuel B, Alcalde-Rabanal, Jacqueline Elizabeth, Alema, Niguse Meles, Ali, Muhammad, Ali, Saqib, Alicandro, Gianfranco, Alijanzadeh, Mehran, Alinia, Cyrus, Alipour, Vahid, Aljunid, Syed Mohamed, Alla, François, Allebeck, Peter, Almasi-Hashiani, Amir, Alonso, Jordi, Al-Raddadi, Rajaa M, Altirkawi, Khalid A, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J, Amini, Saeed, Amini-Rarani, Mostafa, Aminorroaya, Arya, Amiri, Fatemeh, Amit, Arianna Maever L, Amugsi, Dickson A, Amul, Gianna Gayle Herrera, Anderlini, Deanna, Andrei, Catalina Liliana, Andrei, Tudorel, Anjomshoa, Mina, Ansari, Fereshteh, Ansari, Iman, Ansari-Moghaddam, Alireza, Antonio, Carl Abelardo T, Antony, Catherine M, Antriyandarti, Ernoiz, Anvari, Davood, Anwer, Razique, Arabloo, Jalal, Arab-Zozani, Morteza, Aravkin, Aleksandr Y, Ariani, Filippo, Ärnlöv, Johan, Aryal, Krishna K, Arzani, Afsaneh, Asadi-Aliabadi, Mehran, Asadi-Pooya, Ali A, Asghari, Babak, Ashbaugh, Charlie, Atnafu, Desta Debalkie, Atre, Sachin R, Ausloos, Floriane, Ausloos, Marcel, Quintanilla, Beatriz Paulina Ayala, Ayano, Getinet, Ayanore, Martin Amogre, Aynalem, Yared Asmare, Azari, Samad, Azarian, Ghasem, Azene, Zelalem Nigussie, Babaee, Ebrahim, Badawi, Alaa, Bagherzadeh, Mojtaba, Bakhshaei, Mohammad Hossein, Bakhtiari, Ahad, Balakrishnan, Senthilkumar, Balalla, Shivanthi, Balassyano, Shelly, Banach, Maciej, Banik, Palash Chandra, Bannick, Marlena S, Bante, Agegnehu Bante, Baraki, Adhanom Gebreegziabher, Barboza, Miguel A, Barker-Collo, Suzanne Lyn, Barthelemy, Celine M, Barua, Lingkan, Barzegar, Akbar, Basu, Sanjay, Baune, Bernhard T, Bayati, Mohsen, Bazmandegan, Gholamreza, Bedi, Neeraj, Beghi, Ettore, Béjot, Yannick, Bello, Aminu K, Bender, Rose G, Bennett, Derrick A, Bennitt, Fiona B, Bensenor, Isabela M, Benziger, Catherine P, Berhe, Kidanemaryam, Bernabe, Eduardo, Bertolacci, Gregory J, Bhageerathy, Reshmi, Bhala, Neeraj, Bhandari, Dinesh, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhutta, Zulfiqar A, Bibi, Sadia, Biehl, Molly H, Bikbov, Boris, Sayeed, Muhammad 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Alemayehu, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhao, Jeff T, Zhao, Yingxi, Zheng, Peng, Zhou, Maigeng, Ziapour, Arash, Zimsen, Stephanie R M, Naghavi, Mohsen, and Murray, Christopher J L

Abstract

Background In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th a

Published
2020

24. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Vos, Theo, primary, Lim, Stephen S, additional, Abbafati, Cristiana, additional, Abbas, Kaja M, additional, Abbasi, Mohammad, additional, Abbasifard, Mitra, additional, Abbasi-Kangevari, Mohsen, additional, Abbastabar, Hedayat, additional, Abd-Allah, Foad, additional, Abdelalim, Ahmed, additional, Abdollahi, Mohammad, additional, Abdollahpour, Ibrahim, additional, Abolhassani, Hassan, additional, Aboyans, Victor, additional, Abrams, Elissa M, additional, Abreu, Lucas Guimarães, additional, Abrigo, Michael R M, additional, Abu-Raddad, Laith Jamal, additional, Abushouk, Abdelrahman I, additional, Acebedo, Alyssa, additional, Ackerman, Ilana N, additional, Adabi, Maryam, additional, Adamu, Abdu A, additional, Adebayo, Oladimeji M, additional, Adekanmbi, Victor, additional, Adelson, Jaimie D, additional, Adetokunboh, Olatunji O, additional, Adham, Davoud, additional, Afshari, Mahdi, additional, Afshin, Ashkan, additional, Agardh, Emilie E, additional, Agarwal, Gina, additional, Agesa, Kareha M, additional, Aghaali, Mohammad, additional, Aghamir, Seyed Mohammad Kazem, additional, Agrawal, Anurag, additional, Ahmad, Tauseef, additional, Ahmadi, Alireza, additional, Ahmadi, Mehdi, additional, Ahmadieh, Hamid, additional, Ahmadpour, Ehsan, additional, Akalu, Temesgen Yihunie, additional, Akinyemi, Rufus Olusola, additional, Akinyemiju, Tomi, additional, Akombi, Blessing, additional, Al-Aly, Ziyad, additional, Alam, Khurshid, additional, Alam, Noore, additional, Alam, Samiah, additional, Alam, Tahiya, additional, Alanzi, Turki M, additional, Albertson, Samuel B, additional, Alcalde-Rabanal, Jacqueline Elizabeth, additional, Alema, Niguse Meles, additional, Ali, Muhammad, additional, Ali, Saqib, additional, Alicandro, Gianfranco, additional, Alijanzadeh, Mehran, additional, Alinia, Cyrus, additional, Alipour, Vahid, additional, Aljunid, Syed Mohamed, additional, Alla, François, additional, Allebeck, Peter, additional, Almasi-Hashiani, Amir, additional, Alonso, Jordi, additional, Al-Raddadi, Rajaa M, additional, Altirkawi, Khalid A, additional, Alvis-Guzman, Nelson, additional, Alvis-Zakzuk, Nelson J, additional, Amini, Saeed, additional, Amini-Rarani, Mostafa, additional, Aminorroaya, Arya, additional, Amiri, Fatemeh, additional, Amit, Arianna Maever L, additional, Amugsi, Dickson A, additional, Amul, Gianna Gayle Herrera, additional, Anderlini, Deanna, additional, Andrei, Catalina Liliana, additional, Andrei, Tudorel, additional, Anjomshoa, Mina, additional, Ansari, Fereshteh, additional, Ansari, Iman, additional, Ansari-Moghaddam, Alireza, additional, Antonio, Carl Abelardo T, additional, Antony, Catherine M, additional, Antriyandarti, Ernoiz, additional, Anvari, Davood, additional, Anwer, Razique, additional, Arabloo, Jalal, additional, Arab-Zozani, Morteza, additional, Aravkin, Aleksandr Y, additional, Ariani, Filippo, additional, Ärnlöv, Johan, additional, Aryal, Krishna K, additional, Arzani, Afsaneh, additional, Asadi-Aliabadi, Mehran, additional, Asadi-Pooya, Ali A, additional, Asghari, Babak, additional, Ashbaugh, Charlie, additional, Atnafu, Desta Debalkie, additional, Atre, Sachin R, additional, Ausloos, Floriane, additional, Ausloos, Marcel, additional, Ayala Quintanilla, Beatriz Paulina, additional, Ayano, Getinet, additional, Ayanore, Martin Amogre, additional, Aynalem, Yared Asmare, additional, Azari, Samad, additional, Azarian, Ghasem, additional, Azene, Zelalem Nigussie, additional, Babaee, Ebrahim, additional, Badawi, Alaa, additional, Bagherzadeh, Mojtaba, additional, Bakhshaei, Mohammad Hossein, additional, Bakhtiari, Ahad, additional, Balakrishnan, Senthilkumar, additional, Balalla, Shivanthi, additional, Balassyano, Shelly, additional, Banach, Maciej, additional, Banik, Palash Chandra, additional, Bannick, Marlena S, additional, Bante, Agegnehu Bante, additional, Baraki, Adhanom Gebreegziabher, additional, Barboza, Miguel A, additional, Barker-Collo, Suzanne Lyn, additional, Barthelemy, Celine M, additional, Barua, Lingkan, additional, Barzegar, Akbar, additional, Basu, Sanjay, additional, Baune, Bernhard T, additional, Bayati, Mohsen, additional, Bazmandegan, Gholamreza, additional, Bedi, Neeraj, additional, Beghi, Ettore, additional, Béjot, Yannick, additional, Bello, Aminu K, additional, Bender, Rose G, additional, Bennett, Derrick A, additional, Bennitt, Fiona B, additional, Bensenor, Isabela M, additional, Benziger, Catherine P, additional, Berhe, Kidanemaryam, additional, Bernabe, Eduardo, additional, Bertolacci, Gregory J, additional, Bhageerathy, Reshmi, additional, Bhala, Neeraj, additional, Bhandari, Dinesh, additional, Bhardwaj, Pankaj, additional, Bhattacharyya, Krittika, additional, Bhutta, Zulfiqar A, additional, Bibi, Sadia, additional, Biehl, Molly H, additional, Bikbov, Boris, additional, Bin Sayeed, Muhammad Shahdaat, additional, Biondi, Antonio, additional, Birihane, Binyam Minuye, additional, Bisanzio, Donal, additional, Bisignano, Catherine, additional, Biswas, Raaj Kishore, additional, Bohlouli, Somayeh, additional, Bohluli, Mehdi, additional, Bolla, Srinivasa Rao Rao, additional, Boloor, Archith, additional, Boon-Dooley, Alexandra S, additional, Borges, Guilherme, additional, Borzì, Antonio Maria, additional, Bourne, Rupert, additional, Brady, Oliver J, additional, Brauer, Michael, additional, Brayne, Carol, additional, Breitborde, Nicholas J K, additional, Brenner, Hermann, additional, Briant, Paul Svitil, additional, Briggs, Andrew M, additional, Briko, Nikolay Ivanovich, additional, Britton, Gabrielle B, additional, Bryazka, Dana, additional, Buchbinder, Rachelle, additional, Bumgarner, Blair R, additional, Busse, Reinhard, additional, Butt, Zahid A, additional, Caetano dos Santos, Florentino Luciano, additional, Cámera, Luis LA Alberto, additional, Campos-Nonato, Ismael R, additional, Car, Josip, additional, Cárdenas, Rosario, additional, Carreras, Giulia, additional, Carrero, Juan J, additional, Carvalho, Felix, additional, Castaldelli-Maia, Joao Mauricio, additional, Castañeda-Orjuela, Carlos A, additional, Castelpietra, Giulio, additional, Castle, Chris D, additional, Castro, Franz, additional, Catalá-López, Ferrán, additional, Causey, Kate, additional, Cederroth, Christopher R, additional, Cercy, Kelly M, additional, Cerin, Ester, additional, Chandan, Joht Singh, additional, Chang, Alex R, additional, Charlson, Fiona J, additional, Chattu, Vijay Kumar, additional, Chaturvedi, Sarika, additional, Chimed-Ochir, Odgerel, additional, Chin, Ken Lee, additional, Cho, Daniel Youngwhan, additional, Christensen, Hanne, additional, Chu, Dinh-Toi, additional, Chung, Michael T, additional, Cicuttini, Flavia M, additional, Ciobanu, Liliana G, additional, Cirillo, Massimo, additional, Collins, Emma L, additional, Compton, Kelly, additional, Conti, Sara, additional, Cortesi, Paolo Angelo, additional, Costa, Vera Marisa, additional, Cousin, Ewerton, additional, Cowden, Richard G, additional, Cowie, Benjamin C, 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additional, Dhungana, Govinda Prasad, additional, Dianatinasab, Mostafa, additional, Diaz, Daniel, additional, Dibaji Forooshani, Zahra Sadat, additional, Dingels, Zachary V, additional, Dirac, M Ashworth, additional, Djalalinia, Shirin, additional, Do, Hoa Thi, additional, Dokova, Klara, additional, Dorostkar, Fariba, additional, Doshi, Chirag P, additional, Doshmangir, Leila, additional, Douiri, Abdel, additional, Doxey, Matthew C, additional, Driscoll, Tim Robert, additional, Dunachie, Susanna J, additional, Duncan, Bruce B, additional, Duraes, Andre Rodrigues, additional, Eagan, Arielle Wilder, additional, Ebrahimi Kalan, Mohammad, additional, Edvardsson, David, additional, Ehrlich, Joshua R, additional, El Nahas, Nevine, additional, El Sayed, Iman, additional, El Tantawi, Maha, additional, Elbarazi, Iffat, additional, Elgendy, Islam Y, additional, Elhabashy, Hala Rashad, additional, El-Jaafary, Shaimaa I, additional, Elyazar, Iqbal RF, additional, Emamian, Mohammad Hassan, 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Published
2020
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25. Effect of latitude on seasonality of tuberculosis, Australia, 2002-2011

Author

MacLachlan, Jennifer H., Lavender, Caroline J., and Cowie, Benjamin C.

Subjects
Alfacalcidol, Calcifediol, Vitamin D, Tuberculosis -- Care and treatment, Health, World Health Organization
Abstract

Tuberculosis profoundly affects human health, with 5.7 million new or recurrent cases reported and >1 million deaths attributed to the infection by the World Health Organization in 2010 (1). Tuberculosis [...]

Published
2012
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29. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

Author

Roth, G, Abate, D, Abate, K, Abay, S, Abbafati, C, Abbasi, N, Abbastabar, H, Abd-Allah, F, Abdela, J, Abdelalim, A, Abdollahpour, I, Abdulkader, R, Abebe, H, Abebe, M, Abebe, Z, Abejie, A, Abera, S, Abil, O, Abraha, H, Abrham, A, Abu-Raddad, L, Accrombessi, M, Acharya, D, Adamu, A, Adebayo, O, Adedoyin, R, Adekanmbi, V, Adetokunboh, O, Adhena, B, Adib, M, Admasie, A, Afshin, A, Agarwal, G, Agesa, K, Agrawal, A, Agrawal, S, Ahmadi, A, Ahmadi, M, Ahmed, M, Ahmed, S, Aichour, A, Aichour, I, Aichour, M, Akbari, M, Akinyemi, R, Akseer, N, Al-Aly, Z, Al-Eyadhy, A, Al-Raddadi, R, Alahdab, F, Alam, K, Alam, T, Alebel, A, Alene, K, Alijanzadeh, M, Alizadeh-Navaei, R, Aljunid, S, Alkerwi, A, Alla, F, Allebeck, P, Alonso, J, Altirkawi, K, Alvis-Guzman, N, Amare, A, Aminde, L, Amini, E, Ammar, W, Amoako, Y, Anber, N, Andrei, C, Androudi, S, Animut, M, Anjomshoa, M, Ansari, H, Ansha, M, Antonio, C, Anwari, P, Aremu, O, Arnlov, J, Arora, A, Arora, M, Artaman, A, Aryal, K, Asayesh, H, Asfaw, E, Ataro, Z, Atique, S, Atre, S, Ausloos, M, Avokpaho, E, Awasthi, A, Ayala Quintanilla, B, Ayele, Y, Ayer, R, Azzopardi, P, Babazadeh, A, Bacha, U, Badali, H, Badawi, A, Bali, A, Ballesteros, K, Banach, M, Banerjee, K, Bannick, M, Banoub, J, Barboza, M, Barker-Collo, S, Barnighausen, T, Barquera, S, Barrero, L, Bassat, Q, Basu, S, Baune, B, Baynes, H, Bazargan-Hejazi, S, Bedi, N, Beghi, E, Behzadifar, M, Bejot, Y, Bekele, B, Belachew, A, Belay, E, Belay, Y, Bell, M, Bello, A, Bennett, D, Bensenor, I, Berman, A, Bernabe, E, Bernstein, R, Bertolacci, G, Beuran, M, Beyranvand, T, Bhalla, A, Bhattarai, S, Bhaumik, S, Bhutta, Z, Biadgo, B, Biehl, M, Bijani, A, Bikbov, B, Bilano, V, Bililign, N, Bin Sayeed, M, Bisanzio, D, Biswas, T, Blacker, B, Basara, B, Borschmann, R, Bosetti, C, Bozorgmehr, K, Brady, O, Brant, L, Brayne, C, Brazinova, A, Breitborde, N, Brenner, H, Briant, P, Britton, G, Brugha, T, Busse, R, Butt, Z, Callender, C, Campos-Nonato, I, Campuzano Rincon, J, Cano, J, Car, M, Cardenas, R, Carreras, G, Carrero, J, Carter, A, Carvalho, F, Castaneda-Orjuela, C, Castillo Rivas, J, Castle, C, Castro, C, Castro, F, Catala-Lopez, F, Cerin, E, Chaiah, Y, Chang, J, Charlson, F, Chaturvedi, P, Chiang, P, Chimed-Ochir, O, Chisumpa, V, Chitheer, A, Chowdhury, R, Christensen, H, Christopher, D, Chung, S, Cicuttini, F, Ciobanu, L, Cirillo, M, Cohen, A, Cooper, L, Cortesi, P, Cortinovis, M, Cousin, E, Cowie, B, Criqui, M, Cromwell, E, Crowe, C, Crump, J, Cunningham, M, Daba, A, Dadi, A, Dandona, L, Dandona, R, Dang, A, Dargan, P, Daryani, A, Das, S, Gupta, R, Neves, J, Dasa, T, Dash, A, Davis, A, Davis Weaver, N, Davitoiu, D, Davletov, K, De La Hoz, F, De Neve, J, Degefa, M, Degenhardt, L, Degfie, T, Deiparine, S, Demoz, G, Demtsu, B, Denova-Gutierrez, E, Deribe, K, Dervenis, N, Des Jarlais, D, Dessie, G, Dey, S, Dharmaratne, S, Dicker, D, Dinberu, M, Ding, E, Dirac, M, Djalalinia, S, Dokova, K, Doku, D, Donnelly, C, Dorsey, E, Doshi, P, Douwes-Schultz, D, Doyle, K, Driscoll, T, Dubey, M, Dubljanin, E, Duken, E, Duncan, B, Duraes, A, Ebrahimi, H, Ebrahimpour, S, Edessa, D, Edvardsson, D, Eggen, A, El Bcheraoui, C, El Sayed Zaki, M, El-Khatib, Z, Elkout, H, Ellingsen, C, Endres, M, Endries, A, Er, B, Erskine, H, Eshrati, B, Eskandarieh, S, Esmaeili, R, Esteghamati, A, Fakhar, M, Fakhim, H, Faramarzi, M, Fareed, M, Farhadi, F, Farinha, C, Faro, A, Farvid, M, Farzadfar, F, Farzaei, M, Feigin, V, Feigl, A, Fentahun, N, Fereshtehnejad, S, Fernandes, E, Fernandes, J, Ferrari, A, Feyissa, G, Filip, I, Finegold, S, Fischer, F, Fitzmaurice, C, Foigt, N, Foreman, K, Fornari, C, Frank, T, Fukumoto, T, Fuller, J, Fullman, N, Furst, T, Furtado, J, Futran, N, Gallus, S, Garcia-Basteiro, A, Garcia-Gordillo, M, Gardner, W, Gebre, A, Gebrehiwot, T, Gebremedhin, A, Gebremichael, B, Gebremichael, T, Gelano, T, Geleijnse, J, Genova-Maleras, R, Geramo, Y, Gething, P, Gezae, K, Ghadami, M, Ghadimi, R, Ghasemi Falavarjani, K, Ghasemi-Kasman, M, Ghimire, M, Gibney, K, Gill, P, Gill, T, Gillum, R, Ginawi, I, Giroud, M, Giussani, G, Goenka, S, Goldberg, E, Goli, S, Gomez-Dantes, H, Gona, P, Gopalani, S, Gorman, T, Goto, A, Goulart, A, Gnedovskaya, E, Grada, A, Grosso, G, Gugnani, H, Guimaraes, A, Guo, Y, Gupta, P, Gupta, T, Gutierrez, R, Gyawali, B, Haagsma, J, Hafezi-Nejad, N, Hagos, T, Hailegiyorgis, T, Hailu, G, Haj-Mirzaian, A, Hamadeh, R, Hamidi, S, Handal, A, Hankey, G, Harb, H, Harikrishnan, S, Haro, J, Hasan, M, Hassankhani, H, Hassen, H, Havmoeller, R, Hay, R, Hay, S, He, Y, Hedayatizadeh-Omran, A, Hegazy, M, Heibati, B, Heidari, M, Hendrie, D, Henok, A, Henry, N, Herteliu, C, Heydarpour, F, Heydarpour, P, Heydarpour, S, Hibstu, D, Hoek, H, Hole, M, Homaie Rad, E, Hoogar, P, Hosgood, H, Hosseini, S, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Hotez, P, Hoy, D, Hsiao, T, Hu, G, Huang, J, Husseini, A, Hussen, M, Hutfless, S, Idrisov, B, Ilesanmi, O, Iqbal, U, Irvani, S, Irvine, C, Islam, N, Islam, S, Islami, F, Jacobsen, K, Jahangiry, L, Jahanmehr, N, Jain, S, Jakovljevic, M, Jalu, M, James, S, Javanbakht, M, Jayatilleke, A, Jeemon, P, Jenkins, K, Jha, R, Jha, V, Johnson, C, Johnson, S, Jonas, J, Joshi, A, Jozwiak, J, Jungari, S, Jurisson, M, Kabir, Z, Kadel, R, Kahsay, A, Kalani, R, Karami, M, Karami Matin, B, Karch, A, Karema, C, Karimi-Sari, H, Kasaeian, A, Kassa, D, Kassa, G, Kassa, T, Kassebaum, N, Katikireddi, S, Kaul, A, Kazemi, Z, Kazemi Karyani, A, Kazi, D, Kefale, A, Keiyoro, P, Kemp, G, Kengne, A, Keren, A, Kesavachandran, C, Khader, Y, Khafaei, B, Khafaie, M, Khajavi, A, Khalid, N, Khalil, I, Khan, E, Khan, M, Khang, Y, Khater, M, Khoja, A, Khosravi, A, Khosravi, M, Khubchandani, J, Kiadaliri, A, Kibret, G, Kidanemariam, Z, Kiirithio, D, Kim, D, Kim, Y, Kimokoti, R, Kinfu, Y, Kisa, A, Kissimova-Skarbek, K, Kivimaki, M, Knudsen, A, Kocarnik, J, Kochhar, S, Kokubo, Y, Kolola, T, Kopec, J, Koul, P, Koyanagi, A, Kravchenko, M, Krishan, K, Kuate Defo, B, Kucuk Bicer, B, Kumar, G, Kumar, M, Kumar, P, Kutz, M, Kuzin, I, Kyu, H, Lad, D, Lad, S, Lafranconi, A, Lal, D, Lalloo, R, Lallukka, T, Lam, J, Lami, F, Lansingh, V, Lansky, S, Larson, H, Latifi, A, Lau, K, Lazarus, J, Lebedev, G, Lee, P, Leigh, J, Leili, M, Leshargie, C, Li, S, Li, Y, Liang, J, Lim, L, Lim, S, Limenih, M, Linn, S, Liu, S, Liu, Y, Lodha, R, Lonsdale, C, Lopez, A, Lorkowski, S, Lotufo, P, Lozano, R, Lunevicius, R, Ma, S, Macarayan, E, Mackay, M, Maclachlan, J, Maddison, E, Madotto, F, Magdy Abd El Razek, H, Magdy Abd El Razek, M, Maghavani, D, Majdan, M, Majdzadeh, R, Majeed, A, Malekzadeh, R, Malta, D, Manda, A, Mandarano-Filho, L, Manguerra, H, Mansournia, M, Mapoma, C, Marami, D, Maravilla, J, Marcenes, W, Marczak, L, Marks, A, Marks, G, Martinez, G, Martins-Melo, F, Martopullo, I, Marz, W, Marzan, M, Masci, J, Massenburg, B, Mathur, M, Mathur, P, Matzopoulos, R, Maulik, P, Mazidi, M, Mcalinden, C, Mcgrath, J, Mckee, M, Mcmahon, B, Mehata, S, Mehndiratta, M, Mehrotra, R, Mehta, K, Mehta, V, Mekonnen, T, Melese, A, Melku, M, Memiah, P, Memish, Z, Mendoza, W, Mengistu, D, Mengistu, G, Mensah, G, Mereta, S, Meretoja, A, Meretoja, T, Mestrovic, T, Mezgebe, H, Miazgowski, B, Miazgowski, T, Millear, A, Miller, T, Miller-Petrie, M, Mini, G, Mirabi, P, Mirarefin, M, Mirica, A, Mirrakhimov, E, Misganaw, A, Mitiku, H, Moazen, B, Mohammad, K, Mohammadi, M, Mohammadifard, N, Mohammed, M, Mohammed, S, Mohan, V, Mokdad, A, Molokhia, M, Monasta, L, Moradi, G, Moradi-Lakeh, M, Moradinazar, M, Moraga, P, Morawska, L, Velasquez, I, Morgado-Da-Costa, J, Morrison, S, Moschos, M, Mouodi, S, Mousavi, S, Muchie, K, Mueller, U, Mukhopadhyay, S, Muller, K, Mumford, J, Musa, J, Musa, K, Mustafa, G, Muthupandian, S, Nachega, J, Nagel, G, Naheed, A, Nahvijou, A, Naik, G, Nair, S, Najafi, F, Naldi, L, Nam, H, Nangia, V, Nansseu, J, Nascimento, B, Natarajan, G, Neamati, N, Negoi, I, Negoi, R, Neupane, S, Newton, C, Ngalesoni, F, Ngunjiri, J, Nguyen, A, Nguyen, G, Nguyen, H, Nguyen, L, Nguyen, M, Nguyen, T, Nichols, E, Ningrum, D, Nirayo, Y, Nixon, M, Nolutshungu, N, Nomura, S, Norheim, O, Noroozi, M, Norrving, B, Noubiap, J, Nouri, H, Shiadeh, M, Nowroozi, M, Nyasulu, P, Odell, C, Ofori-Asenso, R, Ogbo, F, Oh, I, Oladimeji, O, Olagunju, A, Olivares, P, Olsen, H, Olusanya, B, Olusanya, J, Ong, K, Ong, S, Oren, E, Orpana, H, Ortiz, A, Ortiz, J, Otstavnov, S, Overland, S, Owolabi, M, Ozdemir, R, Mahesh, P, Pacella, R, Pakhale, S, Pakhare, A, Pakpour, A, Pana, A, Panda-Jonas, S, Pandian, J, Parisi, A, Park, E, Parry, C, Parsian, H, Patel, S, Pati, S, Patton, G, Paturi, V, Paulson, K, Pereira, A, Pereira, D, Perico, N, Pesudovs, K, Petzold, M, Phillips, M, Piel, F, Pigott, D, Pillay, J, Pirsaheb, M, Pishgar, F, Polinder, S, Postma, M, Pourshams, A, Poustchi, H, Pujar, A, Prakash, S, Prasad, N, Purcell, C, Qorbani, M, Quintana, H, Quistberg, D, Rade, K, Anwar Rafay, A, Rahim, A, Rahimi, K, Rahimi-Movaghar, A, Rahman, M, Rai, R, Rajsic, S, Ram, U, Ranabhat, C, Ranjan, P, Rao, P, Rawaf, D, Rawaf, S, Razo-Garcia, C, Reddy, K, Reiner, R, Reitsma, M, Remuzzi, G, Renzaho, A, Resnikoff, S, Rezaei, S, Rezaeian, S, Rezai, M, Riahi, S, Ribeiro, A, Rios-Blancas, M, Roba, K, Roberts, N, Robinson, S, Roever, L, Ronfani, L, Roshandel, G, Rostami, A, Rothenbacher, D, Roy, A, Rubagotti, E, Sachdev, P, Saddik, B, Sadeghi, E, Safari, H, Safdarian, M, Safi, S, Safiri, S, Sagar, R, Sahebkar, A, Sahraian, M, Salam, N, Salama, J, Salamati, P, De Freitas Saldanha, R, Saleem, Z, Salimi, Y, Salvi, S, Salz, I, Sambala, E, Samy, A, Sanabria, J, Dolores Sanchez-Nino, M, Santomauro, D, Santos, I, Santos, J, Santric Milicevic, M, Jose, B, Sarker, A, Sarmiento-Suarez, R, Sarrafzadegan, N, Sartorius, B, Sarvi, S, Sathian, B, Satpathy, M, Sawant, A, Sawhney, M, Saxena, S, Sayyah, M, Schaeffner, E, Schmidt, M, Schneider, I, Schottker, B, Schutte, A, Schwebel, D, Schwendicke, F, Scott, J, Sekerija, M, Sepanlou, S, Servan-Mori, E, Seyedmousavi, S, Shabaninejad, H, Shackelford, K, Shafieesabet, A, Shahbazi, M, Shaheen, A, Shaikh, M, Shams-Beyranvand, M, Shamsi, M, Shamsizadeh, M, Sharafi, K, Sharif, M, Sharif-Alhoseini, M, Sharma, R, She, J, Sheikh, A, Shi, P, Shiferaw, M, Shigematsu, M, Shiri, R, Shirkoohi, R, Shiue, I, Shokraneh, F, Shrime, M, Si, S, Siabani, S, Siddiqi, T, Sigfusdottir, I, Sigurvinsdottir, R, Silberberg, D, Santos Silva, D, Silva, J, Da Silva, N, Silveira, D, Singh, J, Singh, N, Singh, P, Singh, V, Sinha, D, Sliwa, K, Smith, M, Sobaih, B, Sobhani, S, Sobngwi, E, Soneji, S, Soofi, M, Sorensen, R, Soriano, J, Soyiri, I, Sposato, L, Sreeramareddy, C, Srinivasan, V, Stanaway, J, Starodubov, V, Stathopoulou, V, Stein, D, Steiner, C, Stewart, L, Stokes, M, Subart, M, Sudaryanto, A, Sufiyan, M, Sur, P, Sutradhar, I, Sykes, B, Sylaja, P, Sylte, D, Szoeke, C, Tabares-Seisdedos, R, Tabuchi, T, Tadakamadla, S, Takahashi, K, Tandon, N, Tassew, S, Taveira, N, Tehrani-Banihashemi, A, Tekalign, T, Tekle, M, Temsah, M, Temsah, O, Terkawi, A, Teshale, M, Tessema, B, Tessema, G, Thankappan, K, Thirunavukkarasu, S, Thomas, N, Thrift, A, Thurston, G, Tilahun, B, To, Q, Tobe-Gai, R, Tonelli, M, Topor-Madry, R, Torre, A, Tortajada-Girbes, M, Touvier, M, Tovani-Palone, M, Tran, B, Tran, K, Tripathi, S, Troeger, C, Truelsen, T, Truong, N, Tsadik, A, Tsoi, D, Tudor Car, L, Murat Tuzcu, E, Tyrovolas, S, Ukwaja, K, Ullah, I, Undurraga, E, Updike, R, Usman, M, Uthman, O, Uzun, S, Vaduganathan, M, Vaezi, A, Vaidya, G, Valdez, P, Varavikova, E, Vasankari, T, Venketasubramanian, N, Villafaina, S, Violante, F, Vladimirov, S, Vlassov, V, Vollset, S, Vos, T, Wagner, G, Wagnew, F, Waheed, Y, Wallin, M, Walson, J, Wang, Y, Wassie, M, Weiderpass, E, Weintraub, R, Weldegebreal, F, Weldegwergs, K, Werdecker, A, Werkneh, A, West, T, Westerman, R, Whiteford, H, Widecka, J, Wilner, L, Wilson, S, Winkler, A, Wiysonge, C, Wolfe, C, Wu, S, Wu, Y, Wyper, G, Xavier, D, Xu, G, Yadgir, S, Yadollahpour, A, Yahyazadeh Jabbari, S, Yakob, B, Yan, L, Yano, Y, Yaseri, M, Yasin, Y, Yentur, G, Yeshaneh, A, Yimer, E, Yip, P, Yirsaw, B, Yisma, E, Yonemoto, N, Yonga, G, Yoon, S, Yotebieng, M, Younis, M, Yousefifard, M, Yu, C, Zadnik, V, Zaidi, Z, Zaman, S, Zamani, M, Zare, Z, Zeleke, A, Zenebe, Z, Zhang, A, Zhang, K, Zhou, M, Zodpey, S, Zuhlke, L, Naghavi, M, Murray, C, Roth, Gregory A., Abate, Degu, Abate, Kalkidan Hassen, Abay, Solomon M., Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Haftom Temesgen, Abebe, Molla, Abebe, Zegeye, Abejie, Ayenew Negesse, Abera, Semaw F., Abil, Olifan Zewdie, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Adamu, Abdu A., Adebayo, Oladimeji M., Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adetokunboh, Olatunji O., Adhena, Beyene Meressa, Adib, Mina G., Admasie, Amha, Afshin, Ashkan, Agarwal, Gina, Agesa, Kareha M., Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmed, Muktar Beshir, Ahmed, Sayem, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Eddine, Akbari, Mohammad Esmaeil, Akinyemi, Rufus Olusola, Akseer, Nadia, Al-Aly, Ziyad, Al-Eyadhy, Ayman, Al-Raddadi, Rajaa M., Alahdab, Fares, Alam, Khurshid, Alam, Tahiya, Alebel, Animut, Alene, Kefyalew Addis, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, Francois, Allebeck, Peter, Alonso, Jordi, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T., Aminde, Leopold N., Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla Hamed, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansari, Hossein, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T., Anwari, Palwasha, Aremu, Olatunde, Arnlov, Johan, Arora, Amit, Arora, Monika, Artaman, Al, Aryal, Krishna K., Asayesh, Hamid, Asfaw, Ephrem Tsegay, Ataro, Zerihun, Atique, Suleman, Atre, Sachin R., Ausloos, Marcel, Avokpaho, Euripide F. G. A., Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Ayele, Yohanes, Ayer, Rakesh, Azzopardi, Peter S., Babazadeh, Arefeh, Bacha, Umar, Badali, Hamid, Badawi, Alaa, Bali, Ayele Geleto, Ballesteros, Katherine E., Banach, Maciej, Banerjee, Kajori, Bannick, Marlena S., Banoub, Joseph Adel Mattar, Barboza, Miguel A., Barker-Collo, Suzanne Lyn, Barnighausen, Till Winfried, Barquera, Simon, Barrero, Lope H., Bassat, Quique, Basu, Sanjay, Baune, Bernhard T., Baynes, Habtamu Wondifraw, Bazargan-Hejazi, Shahrzad, Bedi, Neeraj, Beghi, Ettore, Behzadifar, Masoud, Behzadifar, Meysam, Bejot, Yannick, Bekele, Bayu Begashaw, Belachew, Abate Bekele, Belay, Ezra, Belay, Yihalem Abebe, Bell, Michelle L., Bello, Aminu K., Bennett, Derrick A., Bensenor, Isabela M., Berman, Adam E., Bernabe, Eduardo, Bernstein, Robert S., Bertolacci, Gregory J., Beuran, Mircea, Beyranvand, Tina, Bhalla, Ashish, Bhattarai, Suraj, Bhaumik, Soumyadeeep, Bhutta, Zulfiqar A., Biadgo, Belete, Biehl, Molly H., Bijani, Ali, Bikbov, Boris, Bilano, Ver, Bililign, Nigus, Bin Sayeed, Muhammad Shahdaat, Bisanzio, Donal, Biswas, Tuhin, Blacker, Brigette F., Basara, Berrak Bora, Borschmann, Rohan, Bosetti, Cristina, Bozorgmehr, Kayvan, Brady, Oliver J., Brant, Luisa C., Brayne, Carol, Brazinova, Alexandra, Breitborde, Nicholas J. K., Brenner, Hermann, Briant, Paul Svitil, Britton, Gabrielle, Brugha, Traolach, Busse, Reinhard, Butt, Zahid A., Callender, Charlton S. K. H., Campos-Nonato, Ismael R., Campuzano Rincon, Julio Cesar, Cano, Jorge, Car, Mate, Cardenas, Rosario, Carreras, Giulia, Carrero, Juan J., Carter, Austin, Carvalho, Felix, Castaneda-Orjuela, Carlos A., Castillo Rivas, Jacqueline, Castle, Chris D., Castro, Clara, Castro, Franz, Catala-Lopez, Ferran, Cerin, Ester, Chaiah, Yazan, Chang, Jung-Chen, Charlson, Fiona J., Chaturvedi, Pankaj, Chiang, Peggy Pei-Chia, Chimed-Ochir, Odgerel, Chisumpa, Vesper Hichilombwe, Chitheer, Abdulaal, Chowdhury, Rajiv, Christensen, Hanne, Christopher, Devasahayam J., Chung, Sheng-Chia, Cicuttini, Flavia M., Ciobanu, Liliana G., Cirillo, Massimo, Cohen, Aaron J., Cooper, Leslie Trumbull, Cortesi, Paolo Angelo, Cortinovis, Monica, Cousin, Ewerton, Cowie, Benjamin C., Criqui, Michael H., Cromwell, Elizabeth A., Crowe, Christopher Stephen, Crump, John A., Cunningham, Matthew, Daba, Alemneh Kabeta, Dadi, Abel Fekadu, Dandona, Lalit, Dandona, Rakhi, Dang, Anh Kim, Dargan, Paul I., Daryani, Ahmad, Das, Siddharth K., Gupta, Rajat Das, Neves, Jose Das, Dasa, Tamirat Tesfaye, Dash, Aditya Prasad, Davis, Adrian C., Davis Weaver, Nicole, Davitoiu, Dragos Virgil, Davletov, Kairat, De La Hoz, Fernando Pio, De Neve, Jan-Walter, Degefa, Meaza Girma, Degenhardt, Louisa, Degfie, Tizta T., Deiparine, Selina, Demoz, Gebre Teklemariam, Demtsu, Balem Betsu, Denova-Gutierrez, Edgar, Deribe, Kebede, Dervenis, Nikolaos, Des Jarlais, Don C., Dessie, Getenet Ayalew, Dey, Subhojit, Dharmaratne, Samath D., Dicker, Daniel, Dinberu, Mesfin Tadese, Ding, Eric L., Dirac, M. Ashworth, Djalalinia, Shirin, Dokova, Klara, Doku, David Teye, Donnelly, Christl A., Dorsey, E. 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Abstract

Background: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD 2017 provides a comprehensive assessment of cause-specific mortality for 282 causes in 195 countries and territories from 1980 to 2017. Methods: The causes of death database is composed of vital registration (VR), verbal autopsy (VA), registry, survey, police, and surveillance data. GBD 2017 added ten VA studies, 127 country-years of VR data, 502 cancer-registry country-years, and an additional surveillance country-year. Expansions of the GBD cause of death hierarchy resulted in 18 additional causes estimated for GBD 2017. Newly available data led to subnational estimates for five additional countries—Ethiopia, Iran, New Zealand, Norway, and Russia. Deaths assigned International Classification of Diseases (ICD) codes for non-specific, implausible, or intermediate causes of death were reassigned to underlying causes by redistribution algorithms that were incorporated into uncertainty estimation. We used statistical modelling tools developed for GBD, including the Cause of Death Ensemble model (CODEm), to generate cause fractions and cause-specific death rates for each location, year, age, and sex. Instead of using UN estimates as in previous versions, GBD 2017 independently estimated population size and fertility rate for all locations. Years of life lost (YLLs) were then calculated as the sum of each death multiplied by the standard life expectancy at each age. All rates reported here are age-standardised. Findings: At the broadest grouping of causes of death (Level 1), non-communicable diseases (NCDs) comprised the greatest

Published
2018

41. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Author

Roth, Gregory A, Abate, Degu, Abate, Kalkidan Hassen, Abay, Solomon M, Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Haftom Temesgen, Abebe, Molla, Abebe, Zegeye, Abejie, Ayenew Negesse, Abera, Semaw F, Abil, Olifan Zewdie, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Adamu, Abdu A, Adebayo, Oladimeji M, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adetokunboh, Olatunji O, Adhena, Beyene Meressa, Adib, Mina G, Admasie, Amha, Afshin, Ashkan, Agarwal, Gina, Agesa, Kareha M, Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmed, Muktar Beshir, Ahmed, Sayem, Aichour, Amani Nidhal, Aichour, Ibtihel, Aichour, Miloud Taki Eddine, Akbari, Mohammad Esmaeil, Akinyemi, Rufus Olusola, Akseer, Nadia, Al-Aly, Ziyad, Al-Eyadhy, Ayman, Al-Raddadi, Rajaa M, Alahdab, Fares, Alam, Khurshid, Alam, Tahiya, Alebel, Animut, Alene, Kefyalew Addis, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Alonso, Jordi, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T, Aminde, Leopold N, Amini, Erfan, Ammar, Walid, Amoako, Yaw Ampem, Anber, Nahla Hamed, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansari, Hossein, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Aremu, Olatunde, Ärnlöv, Johan, Arora, Amit, Arora, Monika, Artaman, Al, Aryal, Krishna K, Asayesh, Hamid, Asfaw, Ephrem Tsegay, Ataro, Zerihun, Atique, Suleman, Atre, Sachin R, Ausloos, Marcel, Avokpaho, Euripide F G A, Awasthi, Ashish, Quintanilla, Beatriz Paulina Ayala, Ayele, Yohanes, Ayer, Rakesh, Azzopardi, Peter S, Babazadeh, Arefeh, Bacha, Umar, Badali, Hamid, Badawi, Alaa, Bali, Ayele Geleto, Ballesteros, Katherine E, Banach, Maciej, Banerjee, Kajori, Bannick, Marlena S, 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Subjects
1. No poverty, 16. Peace & justice, 3. Good health

42. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author

Brittney S Sheena, Lindsey Hiebert, Hannah Han, Helen Ippolito, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Amir Abdoli, Hiwa Abubaker Ali, Mesafint Molla Adane, Oyelola A Adegboye, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Muhammad Sohail Afzal, Saira Afzal, Mohamad Aghaie Meybodi, Bahman Ahadinezhad, Bright Opoku Ahinkorah, Sajjad Ahmad, Tauseef Ahmad, Sepideh Ahmadi, Haroon Ahmed, Muktar Beshir Ahmed, Tarik Ahmed Rashid, Gizachew Taddesse Akalu, Addis Aklilu, Tayyaba Akram, Hanadi Al Hamad, Fares Alahdab, Adugnaw Zeleke Alem, Dejene Tsegaye Alem, Fadwa Alhalaiqa Naji Alhalaiqa, Robert Kaba Alhassan, Liaqat Ali, Muhammad Ashar Ali, Yousef Alimohamadi, Vahid Alipour, Motasem Alkhayyat, Sami Almustanyir, Rajaa M Al-Raddadi, Haya Altawalah, Saeed Amini, Hubert Amu, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Amir Anoushiravani, Adnan Ansar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Morteza Arab-Zozani, Ayele Mamo Argaw, Zeleke Gebru Argaw, Muhammad Arshad, Anton A Artamonov, Tahira Ashraf, Daniel Atlaw, Floriane Ausloos, Marcel Ausloos, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Amirhossein Azari Jafari, Ghasem Azarian, Sayna Bagheri, Saeed Bahadory, Atif Amin Baig, Maciej Banach, Nastaran Barati, Amadou Barrow, Abdul-Monim Mohammad Batiha, Diana Fernanda Bejarano Ramirez, Uzma Iqbal Belgaumi, Alemshet Yirga Berhie, Devidas S Bhagat, Nikha Bhardwaj, Pankaj Bhardwaj, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Ali Bijani, Antonio Biondi, Belay Boda Abule Bodicha, Hunduma Amensisa Bojia, Archith Boloor, Cristina Bosetti, Dejana Braithwaite, Nikolay Ivanovich Briko, Zahid A Butt, Luis Alberto Cámera, Raja Chandra Chakinala, Promit Ananyo Chakraborty, Jaykaran Charan, Shu Chen, Jee-Young Jasmine Choi, Sonali Gajanan Choudhari, Fazle Rabbi Chowdhury, Dinh-Toi Chu, Sheng-Chia Chung, Paolo Angelo Cortesi, Benjamin C Cowie, Garland T Culbreth, Omid Dadras, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Fernando Pio De la Hoz, Sisay Abebe Debela, Mohammed Gebre Dedefo, Feleke Mekonnen Demeke, Takele Gezahegn G Demie, Getu Debalkie Demissie, Meseret Derbew Molla, Abebaw Alemayehu Desta, Deepak Dhamnetiya, Mandira Lamichhane Dhimal, Meghnath Dhimal, Mojtaba Didehdar, Linh Phuong Doan, Fariba Dorostkar, Thomas M Drake, Fatemeh Eghbalian, Michael Ekholuenetale, Iman El Sayed, Maysaa El Sayed Zaki, Muhammed Elhadi, Mohamed A Elmonem, Aisha Elsharkawy, Shymaa Enany, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Sharareh Eskandarieh, Firooz Esmaeilzadeh, Sayeh Ezzikouri, Hossein Farrokhpour, Getahun Fetensa, Florian Fischer, Masoud Foroutan, Mohamed M Gad, Abhay Motiramji Gaidhane, Shilpa Gaidhane, Natalie C Galles, Silvano Gallus, Teferi Gebru Gebremeskel, Eyob Alemayehu Gebreyohannes, Keyghobad Ghadiri, Kazem Ghaffari, Mansour Ghafourifard, Seyyed-Hadi Ghamari, Ahmad Ghashghaee, Ali Gholami, Abdolmajid Gholizadeh, Aima Gilani, Amit Goel, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Giuseppe Gorini, Yitayal Ayalew Goshu, Max G Griswold, Mohammed Ibrahim Mohialdeen Gubari, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Rasool Haddadi, Rabih Halwani, Saeed S Hamid, Samer Hamidi, Asif Hanif, Shafiul Haque, Harapan Harapan, Arief Hargono, Sanam Hariri, Ahmed I Hasaballah, S M Mahmudul Hasan, Soheil Hassanipour, Hadi Hassankhani, Simon I Hay, Khezar Hayat, Golnaz Heidari, Claudiu Herteliu, Demisu Zenbaba Heyi, Kamal Hezam, Ramesh Holla, Mohammad-Salar Hosseini, Mostafa Hosseini, Mehdi Hosseinzadeh, Mihaela Hostiuc, Mowafa Househ, Junjie Huang, Nawfal R Hussein, Ivo Iavicoli, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Lalu Muhammad Irham, Jessica Y Islam, Nahlah Elkudssiah Ismail, Kathryn H Jacobsen, Farhad Jadidi-Niaragh, Amirreza Javadi Mamaghani, Shubha Jayaram, Ranil Jayawardena, Rime Jebai, Ravi Prakash Jha, Nitin Joseph, Farahnaz Joukar, Billingsley Kaambwa, Ali Kabir, Zubair Kabir, Rohollah Kalhor, Himal Kandel, Tesfaye K Tesfaye Kanko, Rami S Kantar, Ibraheem M Karaye, Bekalu Getnet Kassa, Phillip M Kemp Bohan, Mohammad Keykhaei, Yousef Saleh Khader, Himanshu Khajuria, Gulfaraz Khan, Imteyaz A Khan, Junaid Khan, Moien AB Khan, Javad Khanali, Amir M Khater, Mahalaqua Nazli Khatib, Mahmoud Khodadost, Abdullah T Khoja, Omid Khosravizadeh, Jagdish Khubchandani, Gyu Ri Kim, Hanna Kim, Min Seo Kim, Yun Jin Kim, Jonathan M Kocarnik, Ali-Asghar Kolahi, Rajasekaran Koteeswaran, G Anil Kumar, Carlo La Vecchia, Dharmesh Kumar Lal, Iván Landires, Savita Lasrado, Jeffrey V Lazarus, Caterina Ledda, Doo Woong Lee, Sang-woong Lee, Yeong Yeh Lee, Miriam Levi, Jiarui Li, Stephen S Lim, Stany W Lobo, Platon D Lopukhov, Joana A Loureiro, Jennifer H MacLachlan, Hassan Magdy Abd El Razek, Muhammed Magdy Abd El Razek, Azeem Majeed, Alaa Makki, Mohammad-Reza Malekpour, Reza Malekzadeh, Ahmad Azam Malik, Fariborz Mansour-Ghanaei, Mohammad Ali Mansournia, Francisco Rogerlândio Martins-Melo, Philippa C Matthews, Walter Mendoza, Ritesh G Menezes, Tuomo J Meretoja, Amanual Getnet Mersha, Tomislav Mestrovic, Ted R Miller, Le Huu Nhat Minh, Andreea Mirica, Seyyedmohammadsadeq Mirmoeeni, Erkin M Mirrakhimov, Sanjeev Misra, Prasanna Mithra, Babak Moazen, Ashraf Mohamadkhani, Mokhtar Mohammadi, Shafiu Mohammed, Nagabhishek Moka, Ali H Mokdad, Jalal Moludi, Sara Momtazmanesh, Lorenzo Monasta, Ghobad Moradi, Maliheh Moradzadeh, Rahmatollah Moradzadeh, Paula Moraga, Ebrahim Mostafavi, Sumaira Mubarik, Malaisamy Muniyandi, Christopher J L Murray, Mohsen Naghavi, Mukhammad David Naimzada, Sreenivas Narasimha Swamy, Zuhair S Natto, Biswa Prakash Nayak, Javad Nazari, Ionut Negoi, Serban Mircea Negru, Seyed Aria Nejadghaderi, Sandhya Neupane Kandel, Huong Lan Thi Nguyen, Che Henry Ngwa, Robina Khan Niazi, Chukwudi A Nnaji, Jean Jacques Noubiap, Ali Nowroozi, Virginia Nuñez-Samudio, Bogdan Oancea, Chimedsuren Ochir, Oluwakemi Ololade Odukoya, In-Hwan Oh, Andrew T Olagunju, Babayemi Oluwaseun Olakunde, Ahmed Omar Bali, Emad Omer, Stanislav S Otstavnov, Bilcha Oumer, Jagadish Rao Padubidri, Adrian Pana, Anamika Pandey, Eun-Cheol Park, Fatemeh Pashazadeh Kan, Urvish K Patel, Uttam Paudel, Ionela-Roxana Petcu, Zahra Zahid Piracha, Richard Charles G Pollok, Maarten J Postma, Akram Pourshams, Hossein Poustchi, Mohammad Rabiee, Navid Rabiee, Alireza Rafiei, Sima Rafiei, Pavan Manibettu Raghuram, Mosiur Rahman, Amir Masoud Rahmani, Setyaningrum Rahmawaty, Aashish Rajesh, Priyanga Ranasinghe, Chythra R Rao, Sowmya J Rao, Mahsa Rashidi, Mohammad-Mahdi Rashidi, David Laith Rawaf, Salman Rawaf, Reza Rawassizadeh, Negar Rezaei, Aziz Rezapour, Sahba Rezazadeh-Khadem, Jefferson Antonio Buendia Rodriguez, Godfrey M Rwegerera, Siamak Sabour, Basema Saddik, Mohammad Reza Saeb, Umar Saeed, Amirhossein Sahebkar, KM Saif-Ur-Rahman, Sarvenaz Salahi, Hamideh Salimzadeh, Chethan Sampath, Abdallah M Samy, Juan Sanabria, Francesco Sanmarchi, Milena M Santric-Milicevic, Arash Sarveazad, Brijesh Sathian, Monika Sawhney, Abdul-Aziz Seidu, Sadaf G Sepanlou, Allen Seylani, Saeed Shahabi, Masood Ali Shaikh, Elaheh Shaker, Murad Ziyaudinovich Shakhmardanov, Mohammed Shannawaz, Suchitra M Shenoy, Jeevan K Shetty, Pavanchand H Shetty, Kenji Shibuya, Jae Il Shin, Parnian Shobeiri, Migbar Mekonnen Sibhat, Achintya Dinesh Singh, Jasvinder A Singh, Surjit Singh, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Amir Ali Sohrabpour, Suhang Song, Seidamir Pasha Tabaeian, Eyayou Girma Tadesse, Majid Taheri, Mircea Tampa, Ker-Kan Tan, Ahmad Tavakoli, Abdelghani Tbakhi, Belay Negash Tefera, Arash Tehrani-Banihashemi, Habtamu Molla Tesfaw, Rekha Thapar, Aravind Thavamani, Seyed Abolfazl Tohidast, Daniel Nigusse Tollosa, Maria Elena Tosti, Marcos Roberto Tovani-Palone, Eugenio Traini, Mai Thi Ngoc Tran, Indang Trihandini, Biruk Shalmeno Tusa, Irfan Ullah, Marco Vacante, Sahel Valadan Tahbaz, Pascual R Valdez, Shoban Babu Varthya, Bay Vo, Yasir Waheed, Adisu Birhanu Weldesenbet, Melat Woldemariam, Suowen Xu, Seyed Hossein Yahyazadeh Jabbari, Mehdi Yaseri, Yigizie Yeshaw, Vahit Yiğit, Birhanu Wubale Yirdaw, Naohiro Yonemoto, Chuanhua Yu, Ismaeel Yunusa, Mazyar Zahir, Leila Zaki, Mohammad Zamani, Maryam Zamanian, Mikhail Sergeevich Zastrozhin, Theo Vos, John W Ward, M Ashworth Dirac, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Sheena, Brittney S, Hiebert, Lindsey, Han, Hannah, Ippolito, Helen, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdoli, Amir, Abubaker Ali, Hiwa, Adane, Mesafint Molla, Adegboye, Oyelola A, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afzal, Muhammad Sohail, Afzal, Saira, Aghaie Meybodi, Mohamad, Ahadinezhad, Bahman, Ahinkorah, Bright Opoku, Ahmad, Sajjad, Ahmad, Tauseef, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Akalu, Gizachew Taddesse, 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Subjects
Liver Cirrhosis, Hepatology, Seroepidemiologic Studies, 3121 General medicine, internal medicine and other clinical medicine, Liver Neoplasms, Gastroenterology, Humans, Bayes Theorem, HBV, Global burden of diseases, HCC, Cirrhosis, Child, Hepatitis B, Global Burden of Disease
Abstract

Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Combating viral hepatitis is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector Strategy on Viral Hepatitis (WHO-GHSS) and Interim Guidance for Country Validation of Viral Hepatitis Elimination (WHO Interim Guidance). We estimated the global, regional, and national prevalence of hepatitis B virus (HBV), as well as mortality and disability-adjusted life-years (DALYs) due to HBV, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This included estimates for 194 WHO member states, for which we compared our estimates to WHO elimination targets. Methods: The primary data sources were population-based serosurveys, claims and hospital discharges, cancer registries, vital registration systems, and published case series. We estimated chronic HBV infection and the burden of HBV-related diseases, defined as an aggregate of cirrhosis due to hepatitis B, liver cancer due to hepatitis B, and acute hepatitis B. We used DisMod-MR 2.1, a Bayesian mixed-effects meta-regression tool, to estimate the prevalence of chronic HBV infection, cirrhosis, and aetiological proportions of cirrhosis. We used mortality-to-incidence ratios modelled with spatiotemporal Gaussian process regression to estimate the incidence of liver cancer. We used the Cause of Death Ensemble modelling (CODEm) model, a tool that selects models and covariates on the basis of out-of-sample performance, to estimate mortality due to cirrhosis, liver cancer, and acute hepatitis B. Findings: In 2019, the estimated global, all-age prevalence of chronic HBV infection was 4·1% (95% uncertainty interval [UI] 3·7 to 4·5), corresponding to 316 million (284 to 351) infected people. There was a 31·3% (29·0 to 33·9) decline in all-age prevalence between 1990 and 2019, with a more marked decline of 76·8% (76·2 to 77·5) in prevalence in children younger than 5 years. HBV-related diseases resulted in 555 000 global deaths (487 000 to 630 000) in 2019. The number of HBV-related deaths increased between 1990 and 2019 (by 5·9% [–5·6 to 19·2]) and between 2015 and 2019 (by 2·9% [–5·9 to 11·3]). By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. We compared estimates for 2019 in 194 WHO locations to WHO-GHSS 2020 targets, and found that four countries achieved a 10% reduction in deaths, 15 countries achieved a 30% reduction in new cases, and 147 countries achieved a 1% prevalence in children younger than 5 years. As of 2019, 68 of 194 countries had already achieved the 2030 target proposed in WHO Interim Guidance of an all-age HBV-related death rate of four per 100 000. Interpretation: The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of hepatitis B vaccination. HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and cohort effects. By 2019, many countries had met the interim seroprevalence target for children younger than 5 years, but few countries had met the WHO-GHSS interim targets for deaths and new cases. Progress according to all indicators must be accelerated to meet 2030 targets, and there are marked disparities in burden and progress across the world. HBV interventions, such as vaccination, testing, and treatment, must be strategically supported and scaled up to achieve elimination. Funding: Bill & Melinda Gates Foundation.

Published
2022

43. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015

Author

Haidong, Wang, Mohsen, Naghavi, Christine, Allen, Ryan M, Barber Zulfi, qar A, Bhutta, Austin, Carter, Daniel C, Casey Fiona, J Charlson, Alan Zian, Chen Matthew, M Coates, Megan, Coggeshall, Lalit, Dandona, Daniel J, Dicker Holly, E Erskine, Alize J, Ferrari, Christina, Fitzmaurice, Kyle, Foreman, Mohammad H, Forouzanfar Maya, S Fraser, Nancy, Fullman, Peter W, Gething Ellen, M Goldberg, Nicholas, Graetz, Juanita A, Haagsma Simon, I Hay, Chantal, Huynh, Catherine O, Johnson Nicholas, J Kassebaum, Yohannes, Kinfu, Xie Rachel, Kulikoff, Michael, Kutz, Hmwe H, Kyu Heidi, J Larson, Janni, Leung, Xiaofeng, Liang, Stephen S, Lim, Margaret, Lind, Rafael, Lozano, Neal, Marquez, George A, Mensah, Joe, Mikesell, Ali H, Mokdad Meghan, D Mooney, Grant, Nguyen, Elaine, Nsoesie, David M, Pigott, Christine, Pinho, Gregory A, Roth Joshua, A Salomon, Logan, Sandar, Naris, Silpakit, Amber, Sligar, Reed J, D Sorensen, Jeff rey, Stanaway, Caitlyn, Steiner, Stephanie, Teeple, Bernadette A, Thomas, 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Hernandez, Julio Cesar Montañez, Montero, Pablo, Montico, Marcella, Montine, Thomas J, Moradi-Lakeh, Maziar, Morawska, Lidia, Morgan, Katherine, Mori, Rintaro, Mozaffarian, Dariush, Mueller, Ulrich O, Murthy, Gudlavalleti Venkata Satyanarayana, Murthy, Sriniva, Musa, Kamarul Imran, Nachega, Jean B, Nagel, Gabriele, Naidoo, Kovin S, Naik, Nitish, Naldi, Luigi, Nangia, Vinay, Nash, Deni, Nejjari, Chakib, Neupane, Suba, Newton, Charles R, Newton, John N, Ng, Marie, Ngalesoni, Frida Namnyak, de Dieu Ngirabega, Jean, Nguyen, Quyen Le, Nisar, Muhammad Imran, Pete, Patrick Martial Nkamedjie, Nomura, Marika, Norheim, Ole F, Norman, Paul E, Norrving, Bo, Nyakarahuka, Luke, Ogbo, Felix Akpojene, Ohkubo, Takayoshi, Ojelabi, Foluke Adetola, Olivares, Pedro R, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Opio, John Nelson, Oren, Eyal, Ortiz, Alberto, Osman, Majdi, Ota, Erika, Ozdemir, Raziye, Pa, Mahesh, Pandian, Jeyaraj D, Pant, Puspa Raj, Papachristou, Christina, Park, Eun-Kee, Park, Jae-Hyun, Parry, Charles D, Parsaeian, Mahboubeh, Caicedo, Angel J Paternina, Patten, Scott B, Patton, George C, Paul, Vinod K, Pearce, Neil, Pedro, João Mário, Stokic, Ljiljana Pejin, Pereira, David M, Perico, Norberto, Pesudovs, Konrad, Petzold, Max, Phillips, Michael Robert, Piel, Frédéric B, Pillay, Julian David, Plass, Dietrich, Platts-Mills, James A, Polinder, Suzanne, Pope, C Arden, Popova, Svetlana, Poulton, Richie G, Pourmalek, Farshad, Prabhakaran, Dorairaj, Qorbani, Mostafa, Quame-Amaglo, Justice, Quistberg, D Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahman, Sajjad Ur, Rai, Rajesh Kumar, Rajavi, Zhale, Rajsic, Sasa, Raju, Murugesan, Rakovac, Ivo, Rana, Saleem M, Ranabhat, Chhabi L, Rangaswamy, Thara, Rao, Puja, Rao, Sowmya R, Refaat, Amany H, Rehm, Jürgen, Reitsma, Marissa B, Remuzzi, Giuseppe, Resnikoff, Serge, Ribeiro, Antonio L, Ricci, Stefano, Blancas, Maria Jesus Rio, Roberts, Bayard, Roca, Anna, Rojas-Rueda, 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Subjects
VITAL-STATISTICS, INTEGRATED APPROACH, ECONOMIC-DEVELOPMENT, DEVELOPMENT ASSISTANCE, UNITED-STATES, Global Health, Communicable Disease, Communicable Diseases, cause of death, Medicine, General & Internal, Life Expectancy, General & Internal Medicine, Humans, Mortality, Medicine(all), Science & Technology, Mortality, Premature, Medicine (all), EPIDEMIOLOGIC TRANSITION, GBD 2015 Mortality and Causes of Death Collaborators, CIVIL REGISTRATION, Public Health, Global Health, Social Medicine and Epidemiology, Articles, 11 Medical And Health Sciences, ROAD TRAFFIC INJURIES, ALZHEIMERS-DISEASE, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, VERBAL AUTOPSY, Life Sciences & Biomedicine, Human
Abstract

Background Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns based on sociodemographic measures. Methods We estimated all-cause mortality by age, sex, geography, and year using an improved analytical approach originally developed for GBD 2013 and GBD 2010. Improvements included refinements to the estimation of child and adult mortality and corresponding uncertainty, parameter selection for under-5 mortality synthesis by spatiotemporal Gaussian process regression, and sibling history data processing. We also expanded the database of vital registration, survey, and census data to 14 294 geography-year datapoints. For GBD 2015, eight causes, including Ebola virus disease, were added to the previous GBD cause list for mortality. We used six modelling approaches to assess cause-specific mortality, with the Cause of Death Ensemble Model (CODEm) generating estimates for most causes. We used a series of novel analyses to systematically quantify the drivers of trends in mortality across geographies. First, we assessed observed and expected levels and trends of cause-specific mortality as they relate to the Socio-demographic Index (SDI), a summary indicator derived from measures of income per capita, educational attainment, and fertility. Second, we examined factors affecting total mortality patterns through a series of counterfactual scenarios, testing the magnitude by which population growth, population age structures, and epidemiological changes contributed to shifts in mortality. Finally, we attributed changes in life expectancy to changes in cause of death. We documented each step of the GBD 2015 estimation processes, as well as data sources, in accordance with Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER). Findings Globally, life expectancy from birth increased from 61.7 years (95% uncertainty interval 61.4-61.9) in 1980 to 71.8 years (71.5-72.2) in 2015. Several countries in sub-Saharan Africa had very large gains in life expectancy from 2005 to 2015, rebounding from an era of exceedingly high loss of life due to HIV/AIDS. At the same time, many geographies saw life expectancy stagnate or decline, particularly for men and in countries with rising mortality from war or interpersonal violence. From 2005 to 2015, male life expectancy in Syria dropped by 11.3 years (3.7-17.4), to 62.6 years (56.5-70.2). Total deaths increased by 4.1% (2.6-5.6) from 2005 to 2015, rising to 55.8 million (54.9 million to 56.6 million) in 2015, but age-standardised death rates fell by 17.0% (15.8-18.1) during this time, underscoring changes in population growth and shifts in global age structures. The result was similar for non-communicable diseases (NCDs), with total deaths from these causes increasing by 14.1% (12.6-16.0) to 39.8 million (39.2 million to 40.5 million) in 2015, whereas age-standardised rates decreased by 13.1% (11.9-14.3). Globally, this mortality pattern emerged for several NCDs, including several types of cancer, ischaemic heart disease, cirrhosis, and Alzheimer's disease and other dementias. By contrast, both total deaths and age-standardised death rates due to communicable, maternal, neonatal, and nutritional conditions significantly declined from 2005 to 2015, gains largely attributable to decreases in mortality rates due to HIV/AIDS (42.1%, 39.1-44.6), malaria (43.1%, 34.7-51.8), neonatal preterm birth complications (29.8%, 24.8-34.9), and maternal disorders (29.1%, 19.3-37.1). Progress was slower for several causes, such as lower respiratory infections and nutritional deficiencies, whereas deaths increased for others, including dengue and drug use disorders. Age-standardised death rates due to injuries significantly declined from 2005 to 2015, yet interpersonal violence and war claimed increasingly more lives in some regions, particularly in the Middle East. In 2015, rotaviral enteritis (rotavirus) was the leading cause of under-5 deaths due to diarrhoea (146 000 deaths, 118 000-183 000) and pneumococcal pneumonia was the leading cause of under-5 deaths due to lower respiratory infections (393 000 deaths, 228 000-532 000), although pathogen-specific mortality varied by region. Globally, the effects of population growth, ageing, and changes in age-standardised death rates substantially differed by cause. Our analyses on the expected associations between cause-specific mortality and SDI show the regular shifts in cause of death composition and population age structure with rising SDI. Country patterns of premature mortality (measured as years of life lost [YLLs]) and how they differ from the level expected on the basis of SDI alone revealed distinct but highly heterogeneous patterns by region and country or territory. Ischaemic heart disease, stroke, and diabetes were among the leading causes of YLLs in most regions, but in many cases, intraregional results sharply diverged for ratios of observed and expected YLLs based on SDI. Communicable, maternal, neonatal, and nutritional diseases caused the most YLLs throughout sub-Saharan Africa, with observed YLLs far exceeding expected YLLs for countries in which malaria or HIV/AIDS remained the leading causes of early death. Interpretation At the global scale, age-specific mortality has steadily improved over the past 35 years; this pattern of general progress continued in the past decade. Progress has been faster in most countries than expected on the basis of development measured by the SDI. Against this background of progress, some countries have seen falls in life expectancy, and age-standardised death rates for some causes are increasing. Despite progress in reducing age-standardised death rates, population growth and ageing mean that the number of deaths from most non-communicable causes are increasing in most countries, putting increased demands on health systems. Copyright (C) The Author(s). Published by Elsevier Ltd.

Published
2016

44. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

Author

Soumya Swaminathan, Berrak Bora Basara, Niveen M E Abu-Rmeileh, Shams Eldin Ali Hassan Khalifa, Nadim E. Karam, Jongmin Lee, Roberto Tchio Talongwa, Inga Dora Sigfusdottir, Yang Yang, Stein Emil Vollset, Joseph R. Masci, Daniel Dicker, Maysaa El Sayed Zaki, Shiwei Liu, Valentina Arsić Arsenijević, Ting Wu Chuang, Linhong Wang, Xiao Rong Wang, Bryan K. Phillips, Don C. Des Jarlais, Vasco Manuel Pedro Machado, Vasiliki Stathopoulou, David Phillips, Luke Nyakarahuka, Leslie T. Cooper, Sandra Nolte, Charles R. Newton, Christina Papachristou, Stephen G. Waller, Carlos Magis-Rodriguez, D. Allen Roberts, Elisabete Weiderpass, Aliya Naheed, Andre Keren, Amanda J. Mason-Jones, Karen J. Courville, Ted R. Miller, Kinnari S. Murthy, Bolajoko O. Olusanya, Tommi Vasankari, Kyle J Foreman, Gabriel Alcalá-Cerra, Yousef Khader, Lorenzo Monasta, Austine Olufemi Adeyemo, Rakhi Dandona, Sanjay Basu, Samir Soneji, Rana J. Asghar, Yohannes Adama Melaku, Rafael Alfonso-Cristancho, John Q. Wong, Yoshihiro Kokubo, Young-Ho Khang, Dhruv S. Kazi, Tom Achoki, Homie Razavi, Uche S. Uchendu, Ashish Bhalla, Ferrán Catalá-López, Peggy Pei-Chia Chiang, Kim Moesgaard Iburg, Kaire Innos, Nicholas J K Breitborde, Zacharie Tsala Dimbuene, Elena Alvarez, Vafa Rahimi-Movaghar, Qing Lan, Simon I. Hay, Kaushalendra Kumar, Ubai Alsharif, Scott B. Patten, Gelin Xu, Theo Vos, Kalpana Balakrishnan, Raghib Ali, Marcella Montico, Andrea P. Silva, Robert G. Weintraub, Timothy M. Wolock, Mohammad Ali Sahraian, Heidi J. Larson, Kingsley N. Ukwaja, Saad B. Omer, Scott Weichenthal, D. Alex Quistberg, Justin Beardsley, Chandrashekhar T Sreeramareddy, Jennifer H MacLachlan, Hsien-Ho Lin, H. Dean Hosgood, Karzan Abdulmuhsin Mohammad, Ryan M Barber, Ibrahim Abubakar, Irma Khonelidze, Ileana B. Heredia Pi, Cyrus Cooper, Hilton Lam, Urbano Fra Paleo, Joshua A. Salomon, Ricky Leung, Farshad Pourmalek, Robert G. Nelson, Konstantinos Stroumpoulis, Megan Coggeshall, Mazin J. Al Kahbouri, Richard G. 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Venkat Narayan, Luca Ronfani, Kazem Rahimi, Vivekanand Jha, Gokalp Kadri Yentur, Wagner Marcenes, Giuseppe Remuzzi, Anwar Rafay, Anand Dayama, Robert Quentin Reilly, Alaa Badawi, Selen Begüm Uzun, James Leigh, Vinay Nangia, Ivy Shiue, J Brown, Nobhojit Roy, Genesis May J. Samonte, Edward J Mills, Soewarta Kosen, Atsushi Goto, Sajjad Ur Rahman, Jose C. Adsuar, Semaw Ferede Abera, Jefferson Traebert, Amiran Gamkrelidze, Andrew H. Kemp, Vasiliy Victorovich Vlassov, André Karch, Edgar P. Simard, Aref A. Bin Abdulhak, Samath D Dharmaratne, Ione Jayce Ceola Schneider, Andre Pascal Kengne, Corine Karema, Harish Chander Gugnani, Reza Assadi, Glen Mola, Paulo A. Lotufo, Christopher J L Murray, Rajeev Gupta, Philimon Gona, Mustafa Z. Younis, Herbert C. Duber, Mitchell T. Wallin, Arjun Lakshmana Balaji, Max Petzold, Francesco Saverio Violante, Monika Sawhney, Kovin Naidoo, Mercedes Colomar, Chuanhua Yu, Mitsuru Mukaigawara, Emerito Jose A. Faraon, Jung-Chen Chang, A Artaman, Muhammad Imran Nisar, Dickens Akena, Xiao Nong Zou, Knud Juel, Mohammed I. Albittar, Mohammad Yahya Saeedi, Sergey Petrovich Ermakov, Ole Frithjof Norheim, Graeme J. Hankey, Jerry Puthenpurakal Abraham, Mouhanad Hammami, Zulfiqar A Bhutta, Rintaro Mori, Maia Kereselidze, Josep Maria Haro, Emily Dansereau, Michael Brainin, Elizabeth Glaser, Ziad A. Memish, Anders Larsson, Solomon Meseret Woldeyohannes, Azmeraw T. Amare, Louisa Degenhardt, Yuichiro Yano, Luke D. Knibbs, Sadaf G. Sepanlou, Hilda L Harb, In-Hwan Oh, Katherine B Gibney, Abdullah Sulieman Terkawi, Adansi A. Amankwaa, Nicholas Graetz, Fortuné Gbètoho Gankpé, Vincent Nowaseb, David M. Pereira, Alan J Thomson, Miguel Angel Alegretti, Rupak Shivakoti, Adnan M. Durrani, Dipan Bose, Saleem M Rana, Mohammad Taghi Hedayati, Mohsen Naghavi, Vegard Skirbekk, Walter Mendoza, Ali H. Mokdad, Soraya Seedat, Zewdie Aderaw Alemu, Edson Serván-Mori, Anil Kaul, Foad Abd-Allah, Paul S. F. 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Silberberg, Yingfeng Zheng, Lydia S. Atkins, Hans W. Hoek, Muluken Dessalegn, David C. Schwebel, Christopher C. Mapoma, Jost B. Jonas, Tolesa Bekele, Ibrahim Abdelmageem Mohamed Ginawi, Bulat Idrisov, Man Mohan Mehndiratta, Thomas N. Williams, Jeffrey A. Towbin, Caterina Guinovart, Jeyaraj D Pandian, Panniyammakal Jeemon, Taavi Lai, Haidong Kan, Tasara T. Mazorodze, Murugesan Raju, Randah R. Hamadeh, Neil Pearce, Melvin Barrientos Marzan, Nima Hafezi-Nejad, John Nelson Opio, Deena Alasfoor, Peter J. Hotez, Jonas Minet Kinge, Peter J. Allen, Eric Y. Tenkorang, Sudan Prasad Neupane, Laith J. Abu-Raddad, Katrina F Ortblad, Arsène Kouablan Adou, Farshad Farzadfar, Sergey Soshnikov, Neeraj Bhala, Sara Sheikhbahaei, Kyle R. Heuton, Michelle L. Bell, Yohannes Kinfu, Takayoshi Ohkubo, Belinda K Lloyd, R. Kumar, Jan Hendrik Richardus, Benjamin O. Anderson, Cell biology, Epidemiology, Public Health, Erasmus MC other, Pathology, Cardiothoracic Surgery, Murray, Christopher J.L, Ortblad, Katrina F., Guinovart, Caterina, Lim, Stephen S., Wolock, Timothy M., Roberts, D. Allen, Dansereau, Emily A., Graetz, Nichola, Barber, Ryan M., Brown, Jonathan C., Wang, Haidong, Duber, Herbert C., Naghavi, Mohsen, Dicker, Daniel, Dandona, Lalit, Salomon, Joshua A., Heuton, Kyle R., Foreman, Kyle, Phillips, David E., Fleming, Thomas D., Flaxman, Abraham D., Phillips, Bryan K., Johnson, Elizabeth K., Coggeshall, Megan S., Abd-Allah, Foad, Abera, Semaw Ferede, Abraham, Jerry P., Abubakar, Ibrahim, Abu-Raddad, Laith J., Abu-Rmeileh, Niveen Me, Achoki, Tom, Adeyemo, Austine Olufemi, Adou, Arsène Kouablan, Adsuar, José C., Agardh, Emilie Elisabet, Akena, Dicken, Al Kahbouri, Mazin J., Alasfoor, Deena, Albittar, Mohammed I., Alcalá-Cerra, Gabriel, Alegretti, Miguel Angel, Alemu, Zewdie Aderaw, Alfonso-Cristancho, Rafael, Alhabib, Samia, Ali, Raghib, Alla, Francoi, Allen, Peter J., Alsharif, Ubai, Alvarez, Elena, Alvis-Guzman, Nelson, Amankwaa, Adansi A., Amare, Azmeraw T., Amini, Hassan, Ammar, Walid, Anderson, Benjamin O., Antonio, Carl Abelardo T., Anwari, Palwasha, Ärnlöv, Johan, Arsic Arsenijevic, Valentina S., Artaman, Ali, Asghar, Rana J., Assadi, Reza, Atkins, Lydia S., Badawi, Alaa, Balakrishnan, Kalpana, Banerjee, Amitava, Basu, Sanjay, Beardsley, Justin, Bekele, Tolesa, Bell, Michelle L., Bernabe, Eduardo, Beyene, Tariku Jibat, Bhala, Neeraj, Bhalla, Ashish, Bhutta, Zulfiqar A., Bin Abdulhak, Aref, Binagwaho, Agne, Blore, Jed D., Bora Basara, Berrak, Bose, Dipan, Brainin, Michael, Breitborde, Nichola, Castañeda-Orjuela, Carlos A., Catalá-López, Ferrán, Chadha, Vineet K., Chang, Jung-Chen, Chiang, Peggy Pei-Chia, Chuang, Ting-Wu, Colomar, Mercede, Cooper, Leslie Trumbull, Cooper, Cyru, Courville, Karen J., Cowie, Benjamin C., Criqui, Michael H., Dandona, Rakhi, Dayama, Anand, De Leo, Diego, Degenhardt, Louisa, Del Pozo-Cruz, Borja, Deribe, Kebede, Des Jarlais, Don C., Dessalegn, Muluken, Dharmaratne, Samath D., Dilmen, Uur, Ding, Eric L., Driscoll, Tim R., Durrani, Adnan M., Ellenbogen, Richard G., Ermakov, Sergey Petrovich, Esteghamati, Alireza, Faraon, Emerito Jose A., Farzadfar, Farshad, Fereshtehnejad, Seyed-Mohammad, Fijabi, Daniel Obadare, Forouzanfar, Mohammad H., Paleo, Urbano Fra., Gaffikin, Lynne, Gamkrelidze, Amiran, Gankpé, Fortuné Gbètoho, Geleijnse, Johanna M., Gessner, Bradford D., Gibney, Katherine B., Ginawi, Ibrahim Abdelmageem Mohamed, Glaser, Elizabeth L., Gona, Philimon, Goto, Atsushi, Gouda, Hebe N., Gugnani, Harish Chander, Gupta, Rajeev, Gupta, Rahul, Hafezi-Nejad, Nima, Hamadeh, Randah Ribhi, Hammami, Mouhanad, Hankey, Graeme J., Harb, Hilda L., Haro, Josep Maria, Havmoeller, Rasmu, Hay, Simon I., Hedayati, Mohammad T., Heredia Pi, Ileana B., Hoek, Hans W., Hornberger, John C., Hosgood, H. Dean, Hotez, Peter J., Hoy, Damian G., Huang, John J., Iburg, Kim M., Idrisov, Bulat T., Innos, Kaire, Jacobsen, Kathryn H., Jeemon, Panniyammakal, Jensen, Paul N., Jha, Vivekanand, Jiang, Guohong, Jonas, Jost B., Juel, Knud, Kan, Haidong, Kankindi, Ida, Karam, Nadim E., Karch, André, Karema, Corine Kakizi, Kaul, Anil, Kawakami, Norito, Kazi, Dhruv S., Kemp, Andrew H., Kengne, Andre Pascal, Keren, Andre, Kereselidze, Maia, Khader, Yousef Saleh, Khalifa, Shams Eldin Ali Hassan, Khan, Ejaz Ahmed, Khang, Young-Ho, Khonelidze, Irma, Kinfu, Yohanne, Kinge, Jonas M., Knibbs, Luke, Kokubo, Yoshihiro, Kosen, S., Kuate Defo, Barthelemy, Kulkarni, Veena S., Kulkarni, Chanda, Kumar, Kaushalendra, Kumar, Ravi B., Kumar, G. Anil, Kwan, Gene F., Lai, Taavi, Lakshmana Balaji, Arjun, Lam, Hilton, Lan, Qing, Lansingh, Van C., Larson, Heidi J., Larsson, Ander, Lee, Jong-Tae, Leigh, Jame, Leinsalu, Mall, Leung, Ricky, Li, Yichong, Li, Yongmei, De Lima, Graça Maria Ferreira, Lin, Hsien-Ho, Lipshultz, Steven E., Liu, Shiwei, Liu, Yang, Lloyd, Belinda K., Lotufo, Paulo A., Machado, Vasco Manuel Pedro, Maclachlan, Jennifer H., Magis-Rodriguez, Carlo, Majdan, Marek, Mapoma, Christopher Chabila, Marcenes, Wagner, Marzan, Melvin Barriento, Masci, Joseph R., Mashal, Mohammad Taufiq, Mason-Jones, Amanda J., Mayosi, Bongani M., Mazorodze, Tasara T., Mckay, Abigail Cecilia, Meaney, Peter A., Mehndiratta, Man Mohan, Mejia-Rodriguez, Fabiola, Melaku, Yohannes Adama, Memish, Ziad A., Mendoza, Walter, Miller, Ted R., Mills, Edward J., Mohammad, Karzan Abdulmuhsin, Mokdad, Ali H., Mola, Glen Liddell, Monasta, Lorenzo, Montico, Marcella, Moore, Ami R., Mori, Rintaro, Moturi, Wilkister Nyaora, Mukaigawara, Mitsuru, Murthy, Kinnari S., Naheed, Aliya, Naidoo, Kovin S., Naldi, Luigi, Nangia, Vinay, Narayan, K.M. Venkat, Nash, Deni, Nejjari, Chakib, Nelson, Robert G., Neupane, Sudan Prasad, Newton, Charles R., Ng, Marie, Nisar, Muhammad Imran, Nolte, Sandra, Norheim, Ole F., Nowaseb, Vincent, Nyakarahuka, Luke, Oh, In-Hwan, Ohkubo, Takayoshi, Olusanya, Bolajoko O., Omer, Saad B., Opio, John Nelson, Orisakwe, Orish Ebere, Pandian, Jeyaraj D., Papachristou, Christina, Paternina Caicedo, Angel J., Patten, Scott B., Paul, Vinod K., Pavlin, Boris Igor, Pearce, Neil, Pereira, David M., Pervaiz, Aslam, Pesudovs, Konrad, Petzold, Max, Pourmalek, Farshad, Qato, Dima, Quezada, Amado D., Quistberg, D. Alex, Rafay, Anwar, Rahimi, Kazem, Rahimi-Movaghar, Vafa, Rahman, Sajjad Ur, Raju, Murugesan, Rana, Saleem M., Razavi, Homie, Reilly, Robert Quentin, Remuzzi, Giuseppe, Richardus, Jan Hendrik, Ronfani, Luca, Roy, Nobhojit, Sabin, Nsanzimana, Saeedi, Mohammad Yahya, Sahraian, Mohammad Ali, Samonte, Genesis May J., Sawhney, Monika, Schneider, Ione J.C., Schwebel, David C., Seedat, Soraya, Sepanlou, Sadaf G., Servan-Mori, Edson E., Sheikhbahaei, Sara, Shibuya, Kenji, Shin, Hwashin Hyun, Shiue, Ivy, Shivakoti, Rupak, Sigfusdottir, Inga Dora, Silberberg, Donald H., Silva, Andrea P., Simard, Edgar P., Singh, Jasvinder A., Skirbekk, Vegard, Sliwa, Karen, Soneji, Samir, Soshnikov, Sergey S., Sreeramareddy, Chandrashekhar T., Stathopoulou, Vasiliki Kalliopi, Stroumpoulis, Konstantino, Swaminathan, Soumya, Sykes, Bryan L., Tabb, Karen M., Talongwa, Roberto Tchio, Tenkorang, Eric Yeboah, Terkawi, Abdullah Sulieman, Thomson, Alan J., Thorne-Lyman, Andrew L., Towbin, Jeffrey A., Traebert, Jefferson, Tran, Bach X., Tsala Dimbuene, Zacharie, Tsilimbaris, Miltiadi, Uchendu, Uche S., Ukwaja, Kingsley N., Uzun, Selen Begüm, Vallely, Andrew J., Vasankari, Tommi J., Venketasubramanian, N., Violante, Francesco S., Vlassov, Vasiliy Victorovich, Vollset, Stein Emil, Waller, Stephen, Wallin, Mitchell T., Wang, Linhong, Wang, Xiao Rong, Wang, Yanping, Weichenthal, Scott, Weiderpass, Elisabete, Weintraub, Robert G., Westerman, Ronny, White, Richard A., Wilkinson, James D., Williams, Thomas Neil, Woldeyohannes, Solomon Meseret, Wong, John Q., Xu, Gelin, Yang, Yang C., Yano, Yuichiro, Yentur, Gokalp Kadri, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa, Yu, Chuanhua, Jin, Kim Yun, El Sayed Zaki, Maysaa, Zhao, Yong, Zheng, Yingfeng, Zhou, Maigeng, Zhu, Jun, Zou, Xiao Nong, Lopez, Alan D., and Vos, Theo

Subjects
Gerontology, SEVERE FEBRILE ILLNESS, Male, verbal autopsy, Nutrition and Disease, Cost effectiveness, MILLENNIUM DEVELOPMENT GOALS, HIV Infections, active antiretroviral therapy, Global Health, COST-EFFECTIVENESS, 0302 clinical medicine, Voeding en Ziekte, Global health, HIV Infection, 030212 general & internal medicine, 0303 health sciences, ACTIVE ANTIRETROVIRAL THERAPY, Incidence (epidemiology), Medicine (all), Incidence, General Medicine, Millennium Development Goals, 3. Good health, middle-income countries, projection package, World Health, VERBAL AUTOPSY, Female, Human, Tuberculosis, Tuberculosi, PROJECTION PACKAGE, prospective cohort, Epidemic, millennium development goals, 03 medical and health sciences, Age Distribution, Acquired immunodeficiency syndrome (AIDS), SDG 3 - Good Health and Well-being, MIDDLE-INCOME COUNTRIES, medicine, Organizational Objective, Humans, Organizational Objectives, FEMALE SEX WORKERS, Mortality, Sex Distribution, Epidemics, cost-effectiveness, female sex workers, 030304 developmental biology, VLAG, business.industry, plasmodium-falciparum malaria, PLASMODIUM-FALCIPARUM MALARIA, medicine.disease, Verbal autopsy, Malaria, PROSPECTIVE COHORT, severe febrile illness, business, Demography
Abstract

BACKGROUND: The Millennium Declaration in 2000 brought special global attention to HIV, tuberculosis, and malaria through the formulation of Millennium Development Goal (MDG) 6. The Global Burden of Disease 2013 study provides a consistent and comprehensive approach to disease estimation for between 1990 and 2013, and an opportunity to assess whether accelerated progress has occured since the Millennium Declaration.METHODS: To estimate incidence and mortality for HIV, we used the UNAIDS Spectrum model appropriately modified based on a systematic review of available studies of mortality with and without antiretroviral therapy (ART). For concentrated epidemics, we calibrated Spectrum models to fit vital registration data corrected for misclassification of HIV deaths. In generalised epidemics, we minimised a loss function to select epidemic curves most consistent with prevalence data and demographic data for all-cause mortality. We analysed counterfactual scenarios for HIV to assess years of life saved through prevention of mother-to-child transmission (PMTCT) and ART. For tuberculosis, we analysed vital registration and verbal autopsy data to estimate mortality using cause of death ensemble modelling. We analysed data for corrected case-notifications, expert opinions on the case-detection rate, prevalence surveys, and estimated cause-specific mortality using Bayesian meta-regression to generate consistent trends in all parameters. We analysed malaria mortality and incidence using an updated cause of death database, a systematic analysis of verbal autopsy validation studies for malaria, and recent studies (2010-13) of incidence, drug resistance, and coverage of insecticide-treated bednets.FINDINGS: Globally in 2013, there were 1·8 million new HIV infections (95% uncertainty interval 1·7 million to 2·1 million), 29·2 million prevalent HIV cases (28·1 to 31·7), and 1·3 million HIV deaths (1·3 to 1·5). At the peak of the epidemic in 2005, HIV caused 1·7 million deaths (1·6 million to 1·9 million). Concentrated epidemics in Latin America and eastern Europe are substantially smaller than previously estimated. Through interventions including PMTCT and ART, 19·1 million life-years (16·6 million to 21·5 million) have been saved, 70·3% (65·4 to 76·1) in developing countries. From 2000 to 2011, the ratio of development assistance for health for HIV to years of life saved through intervention was US$4498 in developing countries. Including in HIV-positive individuals, all-form tuberculosis incidence was 7·5 million (7·4 million to 7·7 million), prevalence was 11·9 million (11·6 million to 12·2 million), and number of deaths was 1·4 million (1·3 million to 1·5 million) in 2013. In the same year and in only individuals who were HIV-negative, all-form tuberculosis incidence was 7·1 million (6·9 million to 7·3 million), prevalence was 11·2 million (10·8 million to 11·6 million), and number of deaths was 1·3 million (1·2 million to 1·4 million). Annualised rates of change (ARC) for incidence, prevalence, and death became negative after 2000. Tuberculosis in HIV-negative individuals disproportionately occurs in men and boys (versus women and girls); 64·0% of cases (63·6 to 64·3) and 64·7% of deaths (60·8 to 70·3). Globally, malaria cases and deaths grew rapidly from 1990 reaching a peak of 232 million cases (143 million to 387 million) in 2003 and 1·2 million deaths (1·1 million to 1·4 million) in 2004. Since 2004, child deaths from malaria in sub-Saharan Africa have decreased by 31·5% (15·7 to 44·1). Outside of Africa, malaria mortality has been steadily decreasing since 1990.INTERPRETATION: Our estimates of the number of people living with HIV are 18·7% smaller than UNAIDS's estimates in 2012. The number of people living with malaria is larger than estimated by WHO. The number of people living with HIV, tuberculosis, or malaria have all decreased since 2000. At the global level, upward trends for malaria and HIV deaths have been reversed and declines in tuberculosis deaths have accelerated. 101 countries (74 of which are developing) still have increasing HIV incidence. Substantial progress since the Millennium Declaration is an encouraging sign of the effect of global action.FUNDING: Bill & Melinda Gates Foundation.

Published
2014

45. A pilot project harnessing surveillance systems to support clinicians providing clinical care for people diagnosed with hepatitis C in Victoria, Australia, September 2021 to 31 March 2022.

Author

Abbott M, MacLachlan JH, Romero N, Matthews N, Higgins N, Lee A, Stoove M, Marukutira T, Quinn B, Allard NL, and Cowie BC

Subjects
Humans, Pilot Projects, Male, Female, Middle Aged, Adult, Victoria, Disease Notification, Aged, Hepacivirus isolation & purification, Hepacivirus genetics, Population Surveillance methods, Contact Tracing methods, Hepatitis C, Chronic diagnosis, Hepatitis C diagnosis
Abstract

BackgroundActive follow-up of chronic hepatitis C notifications to promote linkage to care is a promising strategy to support elimination.AimThis pilot study in Victoria, Australia, explored if the Department of Health could follow-up on hepatitis C cases through their diagnosing clinicians, to assess and support linkage to care and complete data missing from the notification.MethodsFor notifications received between 1 September 2021 and 31 March 2022 of unspecified hepatitis C cases (i.e. acquired > 24 months ago or of unknown duration), contact with diagnosing clinicians was attempted. Data were collected on risk exposures, clinical and demographic characteristics and follow-up care (i.e. HCV RNA test; referral or ascertainment of previous negative testing or treatment history). Reasons for unsuccessful doctor contact and gaps in care provision were investigated. Advice to clinicians on care and resources for clinical support were given on demand.ResultsOf 513 cases where information was sought, this was able to be obtained for 356 (69.4%). Reasons for unsuccessful contact included incomplete contact details or difficulties getting in touch across three attempts, particularly for hospital diagnoses. Among the 356 cases, 307 (86.2%) had received follow-up care. Patient-management resources were requested by 100 of 286 contacted diagnosing clinicians.ConclusionsMost doctors successfully contacted had provided follow-up care. Missing contact information and the time taken to reach clinicians significantly impeded the feasibility of the intervention. Enhancing system automation, such as integration of laboratory results, could improve completeness of notifications and support further linkage to care where needed.

Published
2024
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46. Hepatitis B virus epidemiology.

Author

MacLachlan JH and Cowie BC

Subjects
DNA, Viral genetics, Hepatitis B virus genetics, Humans, Risk Factors, Carcinoma, Hepatocellular virology, Hepatitis B, Chronic complications, Hepatitis B, Chronic epidemiology, Liver Cirrhosis virology, Liver Neoplasms virology
Abstract

The epidemiology of hepatitis B virus (HBV) infection is geographically diverse, with population prevalence, age and mode of acquisition, and likelihood of progression to chronic infection mutually interdependent. The burden of chronic HBV infection is increasingly being recognized, with cirrhosis and liver cancer attributable to HBV continuing to increase. The outcomes of chronic HBV infection are affected by a range of factors, including viral genotype, the presence of coinfections with other blood-borne viruses, and the impact of other causes of liver disease. The increased recognition of HBV infection as a leading cause of death globally has resulted in the development of new structures and policies at the international level; immediate attention to implementing these strategies is now required., (Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.)

Published
2015
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47. Mortality due to viral hepatitis in the Global Burden of Disease Study 2010: new evidence of an urgent global public health priority demanding action.

Author

Cowie BC, Carville KS, and MacLachlan JH

Subjects
Adenine analogs & derivatives, Adenine therapeutic use, Global Health, Hepatitis, Viral, Human drug therapy, Humans, Organophosphonates therapeutic use, Public Health, Reverse Transcriptase Inhibitors therapeutic use, Tenofovir, Healthy People Programs, Hepatitis, Viral, Human epidemiology, Hepatitis, Viral, Human mortality
Abstract

The recently published Global Burden of Disease Study 2010 (GBD 2010) contains accurate, contemporary estimates of human morbidity and mortality, with substantial changes in the patterns of illness observed over the last two decades. One of the most significant alterations to these estimates has been the recognition that viral hepatitis is a leading cause of human mortality, with an estimated 1.29 million deaths worldwide in 2010. The global community must act to address emerging health priorities identified by GBD 2010, including the need to provide treatment and care to people living with viral hepatitis, especially in resource-poor settings.

Published
2013
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