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1. Adolescent body mass index and changes in pre-pregnancy body mass index in relation to risk of gestational diabetes

Author

Gabriel Chodick, Maayan Omer-Gilon, Estela Derazne, Gal Puris, Ran Rotem, Dorit Tzur, Orit Pinhas-Hamiel, Tali Cukierman-Yaffe, Avi Shina, Inbar Zucker, Amir Tirosh, Arnon Afek, Varda Shalev, and Gilad Twig

Subjects
gestational, diabetes, GDM, BMI, Adolescent, pregnancy, Medicine (General), R5-920
Abstract

Background: Pregestational excessive body mass index (BMI) is linked to an increased risk for gestational diabetes mellitus (GDM), but less is known on the effect of adolescent BMI on GDM occurrence. The study aimed to investigate possible associations of adolescent BMI and changes in BMI experienced before first pregnancy, with gestational diabetes risk. Methods: This retrospective study was based on linkage of a military screening database of adolescent health status (Israel Defence Forces) including measured height and weight, with medical records (Maccabi Healthcare Services, MHS) of a state-mandated health provider. The latter covers about 25% of the Israeli population; about 90% of pregnant women undergo screening by the two-step Carpenter-Coustan method. Adolescent BMI was categorized according to Center of Disease Control and Prevention percentiles. Only first documented pregnanies were analyzed and GDM was the outcome. Findings: Of 190,905 nulliparous women, 10,265 (5.4%) developed GDM. Incidence proportions of GDM were 5.1%, 6.1%, 7.3%, and 8.9% among women with adolescent normal BMI, underweight, overweight, and obesity (p

Published
2021
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2. Adolescent body mass index and changes in pre-pregnancy body mass index in relation to risk of gestational diabetes

Author

Maayan Omer-Gilon, Orit Pinhas-Hamiel, Estela Derazne, Dorit Tzur, Gilad Twig, Amir Tirosh, Varda Shalev, Inbar Zucker, Ran S Rotem, Gal Puris, Arnon Afek, Avi Shina, Gabriel Chodick, and Tali Cukierman-Yaffe

Subjects
Medicine (General), medicine.medical_specialty, GAM, generalized additive model, GDM, Adolescent, BMI, body mass index, Population, Overweight, BMI, R5-920, medicine, education, Original Research, education.field_of_study, Pregnancy, diabetes, GDM, gestational diabetes mellitus, business.industry, Obstetrics, GCT, glucose challenge test, SES, socioeconomic status, nutritional and metabolic diseases, General Medicine, medicine.disease, Obesity, OR, odds ratio, Gestational diabetes, CI, confidence intervals, MHS, Maccabi Healthcare Services, pregnancy, women, Underweight, medicine.symptom, gestational, SD, standard deviation, business, Body mass index, Adolescent health
Abstract

Background: Pregestational excessive body mass index (BMI) is linked to an increased risk for gestational diabetes mellitus (GDM), but less is known on the effect of adolescent BMI on GDM occurrence. The study aimed to investigate possible associations of adolescent BMI and changes in BMI experienced before first pregnancy, with gestational diabetes risk. Methods: This retrospective study was based on linkage of a military screening database of adolescent health status (Israel Defence Forces) including measured height and weight, with medical records (Maccabi Healthcare Services, MHS) of a state-mandated health provider. The latter covers about 25% of the Israeli population; about 90% of pregnant women undergo screening by the two-step Carpenter-Coustan method. Adolescent BMI was categorized according to Center of Disease Control and Prevention percentiles. Only first documented pregnanies were analyzed and GDM was the outcome. Findings: Of 190,905 nulliparous women, 10,265 (5.4%) developed GDM. Incidence proportions of GDM were 5.1%, 6.1%, 7.3%, and 8.9% among women with adolescent normal BMI, underweight, overweight, and obesity (p

Published
2021
Full Text
View/download PDF

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