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7. Competing risk analysis of cardiovascular disease risk in breast cancer patients receiving a radiation boost

Author

Circulatory Health, Cancer, Cardiometabolic Health, Trialbureau Beeld, MS Radiotherapie, Koop, Yvonne, Atsma, Femke, Batenburg, Marilot C T, Meijer, Hanneke, van der Leij, Femke, Gal, Roxanne, van Velzen, Sanne G M, Išgum, Ivana, Vermeulen, Hester, Maas, Angela H E M, Messaoudi, Saloua El, Verkooijen, Helena M, Circulatory Health, Cancer, Cardiometabolic Health, Trialbureau Beeld, MS Radiotherapie, Koop, Yvonne, Atsma, Femke, Batenburg, Marilot C T, Meijer, Hanneke, van der Leij, Femke, Gal, Roxanne, van Velzen, Sanne G M, Išgum, Ivana, Vermeulen, Hester, Maas, Angela H E M, Messaoudi, Saloua El, and Verkooijen, Helena M

Published
2024

8. Urinary incontinence more than 15 years after premenopausal risk-reducing salpingo-oophorectomy: a multicentre cross-sectional study

Author

MS Gynaecologische Oncologie, Cancer, Genetica Klinische Genetica, Terra, Lara, Heemskerk-Gerritsen, Bernadette A M, Beekman, Maarten J, Engelhardt, Ellen, Mourits, Marian J E, van Doorn, Helena C, de Hullu, Joanna A, Mom, Constantijne H, Slangen, Brigitte F M, Gaarenstroom, Katja N, van Beurden, Marc, Roeters Van Lennep, Jeanine E, van Dorst, Eleonora B L, van der Kolk, Lizet E, Collée, J Margriet, Wevers, Marijke R, Ausems, Margreet G E M, van Engelen, Klaartje, van de Beek, Irma, Berger, Lieke P V, van Asperen, Christi J, Gomez Garcia, Encarna B, Maas, Angela H E M, Hooning, Maartje J, Steensma, Anneke B, van Leeuwen, Flora E, MS Gynaecologische Oncologie, Cancer, Genetica Klinische Genetica, Terra, Lara, Heemskerk-Gerritsen, Bernadette A M, Beekman, Maarten J, Engelhardt, Ellen, Mourits, Marian J E, van Doorn, Helena C, de Hullu, Joanna A, Mom, Constantijne H, Slangen, Brigitte F M, Gaarenstroom, Katja N, van Beurden, Marc, Roeters Van Lennep, Jeanine E, van Dorst, Eleonora B L, van der Kolk, Lizet E, Collée, J Margriet, Wevers, Marijke R, Ausems, Margreet G E M, van Engelen, Klaartje, van de Beek, Irma, Berger, Lieke P V, van Asperen, Christi J, Gomez Garcia, Encarna B, Maas, Angela H E M, Hooning, Maartje J, Steensma, Anneke B, and van Leeuwen, Flora E

Published
2024

9. Long-Term Morbidity and Health After Early Menopause Due to Oophorectomy in Women at Increased Risk of Ovarian Cancer: Protocol for a Nationwide Cross-Sectional Study With Prospective Follow-Up (HARMOny Study)

Author

Terra, Lara, Hooning, Maartje J, Heemskerk-Gerritsen, Bernadette A M, van Beurden, Marc, Roeters van Lennep, Jeanine E, van Doorn, Helena C, de Hullu, Joanne A, Mom, Constantijne, van Dorst, Eleonora B L, Mourits, Marian J E, Slangen, Brigitte F M, Gaarenstroom, Katja N, Zillikens, M Carola, Leiner, Tim, van der Kolk, Lizet, Collee, Margriet, Wevers, Marijke, Ausems, Margreet G E M, van Engelen, Klaartje, Berger, Lieke PV, van Asperen, Christi J, Gomez-Garcia, Encarna B, van de Beek, Irma, Rookus, Matti A, Hauptmann, Michael, Bleiker, Eveline M, Schagen, Sanne B, Aaronson, Neil K, Maas, Angela H E M, and van Leeuwen, Flora E

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundBRCA1/2 mutation carriers are recommended to undergo risk-reducing salpingo-oophorectomy (RRSO) at 35 to 45 years of age. RRSO substantially decreases ovarian cancer risk, but at the cost of immediate menopause. Knowledge about the potential adverse effects of premenopausal RRSO, such as increased risk of cardiovascular disease, osteoporosis, cognitive dysfunction, and reduced health-related quality of life (HRQoL), is limited. ObjectiveThe aim of this study is to assess the long-term health effects of premenopausal RRSO on cardiovascular disease, bone health, cognitive functioning, urological complaints, sexual functioning, and HRQoL in women with high familial risk of breast or ovarian cancer. MethodsWe will conduct a multicenter cross-sectional study with prospective follow-up, nested in a nationwide cohort of women at high familial risk of breast or ovarian cancer. A total of 500 women who have undergone RRSO before 45 years of age, with a follow-up period of at least 10 years, will be compared with 250 women (frequency matched on current age) who have not undergone RRSO or who have undergone RRSO at over 55 years of age. Participants will complete an online questionnaire on lifestyle, medical history, cardiovascular risk factors, osteoporosis, cognitive function, urological complaints, and HRQoL. A full cardiovascular assessment and assessment of bone mineral density will be performed. Blood samples will be obtained for marker analysis. Cognitive functioning will be assessed objectively with an online neuropsychological test battery. ResultsThis study was approved by the institutional review board in July 2018. In February 2019, we included our first participant. As of November 2020, we had enrolled 364 participants in our study. ConclusionsKnowledge from this study will contribute to counseling women with a high familial risk of breast/ovarian cancer about the long-term health effects of premenopausal RRSO. The results can also be used to offer health recommendations after RRSO. Trial RegistrationClinicalTrials.gov NCT03835793; https://clinicaltrials.gov/ct2/show/NCT03835793. International Registered Report Identifier (IRRID)DERR1-10.2196/24414

Published
2021
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16. Effect of Diltiazem Versus Placebo on Microvascular Dysfunction Assessed By Repeated Continuous Thermodilution Measurements: Results of the EDIT‐CMD Trial

Author

Jansen, Tijn P. J., primary, de Vos, Annemiek, additional, Elias‐Smale, Suzette E., additional, Paradies, Valeria, additional, Konst, Regina E., additional, Crooijmans, Caïa, additional, Dimitriu‐Leen, Aukelien C., additional, Rodwell, Laura, additional, Maas, Angela H. E. M., additional, Smits, Pieter C., additional, van Royen, Niels, additional, and Damman, Peter, additional

Published
2023
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17. Continuous Versus Bolus Thermodilution‐Derived Coronary Flow Reserve and Microvascular Resistance Reserve and Their Association With Angina and Quality of Life in Patients With Angina and Nonobstructive Coronaries: A Head‐to‐Head Comparison

Author

Jansen, Tijn P. J., primary, de Vos, Annemiek, additional, Paradies, Valeria, additional, Dimitriu‐Leen, Aukelien, additional, Crooijmans, Caïa, additional, Elias‐Smale, Suzette, additional, Rodwell, Laura, additional, Maas, Angela H. E. M., additional, Smits, Pieter C., additional, Pijls, Nico, additional, van Royen, Niels, additional, and Damman, Peter, additional

Published
2023
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20. Urinary incontinence more than 15 years after premenopausal risk‐reducing salpingo‐oophorectomy: a multicentre cross‐sectional study

Author

Terra, Lara, primary, Heemskerk‐Gerritsen, Bernadette A. M., additional, Beekman, Maarten J., additional, Engelhardt, Ellen, additional, Mourits, Marian J. E., additional, van Doorn, Helena C., additional, de Hullu, Joanna A., additional, Mom, Constantijne H., additional, Slangen, Brigitte F. M., additional, Gaarenstroom, Katja N., additional, van Beurden, Marc, additional, Roeters Van Lennep, Jeanine E., additional, van Dorst, Eleonora B. L., additional, van der Kolk, Lizet E., additional, Collée, J. Margriet, additional, Wevers, Marijke R., additional, Ausems, Margreet G .E. M., additional, van Engelen, Klaartje, additional, van de Beek, Irma, additional, Berger, Lieke P. V., additional, van Asperen, Christi J., additional, Gomez Garcia, Encarna B., additional, Maas, Angela H. E. M., additional, Hooning, Maartje J., additional, Steensma, Anneke B., additional, and van Leeuwen, Flora E., additional

Published
2023
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25. Sexual functioning more than 15 years after premenopausal risk-reducing salpingo-oophorectomy

Author

MS Gynaecologische Oncologie, Cancer, Genetica Klinische Genetica, Terra, Lara, Beekman, Maarten J, Engelhardt, Ellen G, Heemskerk-Gerritsen, Bernadette A M, Van Beurden, Marc, Roeters Van Lennep, Jeanine E, Van Doorn, Helena C, De Hullu, Joanne A, Van Dorst, Eleonora B L, Mom, Constantijne H, Slangen, Brigitte F M, Gaarenstroom, Katja N, van der Kolk, Lizet E, Margriet Collée, J, Wevers, Marijke R, Ausems, Margreet G E M, Van Engelen, K, Van De Beek, I, Berger, Lieke P V, Van Asperen, Christi J, Gomez Garcia, Encarna B, Maas, Angela H E M, Hooning, Maartje J, Aaronson, Neil K, Mourits, Marian J E, Van Leeuwen, Flora E, MS Gynaecologische Oncologie, Cancer, Genetica Klinische Genetica, Terra, Lara, Beekman, Maarten J, Engelhardt, Ellen G, Heemskerk-Gerritsen, Bernadette A M, Van Beurden, Marc, Roeters Van Lennep, Jeanine E, Van Doorn, Helena C, De Hullu, Joanne A, Van Dorst, Eleonora B L, Mom, Constantijne H, Slangen, Brigitte F M, Gaarenstroom, Katja N, van der Kolk, Lizet E, Margriet Collée, J, Wevers, Marijke R, Ausems, Margreet G E M, Van Engelen, K, Van De Beek, I, Berger, Lieke P V, Van Asperen, Christi J, Gomez Garcia, Encarna B, Maas, Angela H E M, Hooning, Maartje J, Aaronson, Neil K, Mourits, Marian J E, and Van Leeuwen, Flora E

Published
2023

27. Long‐term effects of premenopausal risk‐reducing salpingo‐oophorectomy on cognition in women with high familial risk of ovarian cancer: A cross‐sectional study

Author

Terra, Lara, primary, Lee Meeuw Kjoe, Philippe R., additional, Agelink Van Rentergem, Joost A., additional, Beekman, Maarten J., additional, Heemskerk‐Gerritsen, Bernadette A. M., additional, Van Beurden, Marc, additional, Roeters Van Lennep, Jeanine E., additional, Van Doorn, Helena C., additional, De Hullu, Joanna A., additional, Mourits, Marian J. E., additional, Van Dorst, Eleonora B. L., additional, Mom, Constantijne H., additional, Slangen, Brigitte F. M., additional, Gaarenstroom, Katja N., additional, van der Kolk, Lizet E., additional, Collée, J. Margriet, additional, Wevers, Marijke R., additional, Ausems, Margreet G. E. M., additional, Van Engelen, Klaartje, additional, Van De Beek, Irma, additional, Berger, Lieke P. V., additional, Van Asperen, Christi J., additional, Gomez Garcia, Encarna B., additional, Maas, Angela H. E. M., additional, Hooning, Maartje J., additional, Van Der Wall, Elsken, additional, Van Leeuwen, Flora E., additional, and Schagen, Sanne B., additional

Published
2023
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28. Sex differences in arterial hypertension A scientific statement from the ESC Council on Hypertension, the European Association of Preventive Cardiology, Association of Cardiovascular Nursing and Allied Professions, the ESC Council for Cardiology Practice, and the ESC Working Group on Cardiovascular Pharmacotherapy

Author

Gerdts, Eva, Sudano, Isabella, Brouwers, Sofie, Borghi, Claudio, Bruno, Rosa Maria, Ceconi, Claudio, Cornelissen, Veronique, Diévart, François, Ferrini, Marc, Kahan, Thomas, Løchen, Maja Lisa, Maas, Angela H E M, Mahfoud, Felix, Mihailidou, Anastasia S, Moholdt, Trine, Parati, Gianfranco, de Simone, Giovanni, Faculty of Medicine and Pharmacy, Brussels Heritage Lab, Pharmaceutical and Pharmacological Sciences, and Experimental Pharmacology

Subjects
hypertension, Cardiac & Cardiovascular Systems, CONSENSUS DOCUMENT, BLOOD-PRESSURE, END-POINT REDUCTION, Hypertension-mediated organ damage, ANTIHYPERTENSIVE TREATMENT, LOSARTAN INTERVENTION, sex hormones, pharmacological treatment, LEFT-VENTRICULAR HYPERTROPHY, Internal Medicine, Blood Pressure regulators, Sex hormones, GENDER-DIFFERENCES, Science & Technology, LEFT ATRIAL SIZE, Cardiovascular disease, adverse events, PULSE-WAVE VELOCITY, Adverse events, Hypertension, Cardiovascular System & Cardiology, RISK-FACTORS, Sex, pharmacology, Cardiology and Cardiovascular Medicine, Life Sciences & Biomedicine, Pharmacological treatment
Abstract

There is strong evidence that sex chromosomes and sex hormones influence blood pressure (BP) regulation, distribution of cardiovascular (CV) risk factors and co-morbidities differentially in females and males with essential arterial hypertension. The risk for CV disease increases at a lower BP level in females than in males, suggesting that sex-specific thresholds for diagnosis of hypertension may be reasonable. However, due to paucity of data, in particularly from specifically designed clinical trials, it is not yet known whether hypertension should be differently managed in females and males, including treatment goals and choice and dosages of antihypertensive drugs. Accordingly, this consensus document was conceived to provide a comprehensive overview of current knowledge on sex differences in essential hypertension including BP development over the life course, development of hypertension, pathophysiologic mechanisms regulating BP, interaction of BP with CV risk factors and co-morbidities, hypertension-mediated organ damage in the heart and the arteries, impact on incident CV disease, and differences in the effect of antihypertensive treatment. The consensus document also highlights areas where focused research is needed to advance sex-specific prevention and management of hypertension. ispartof: EUROPEAN HEART JOURNAL vol:43 issue:46 pages:4777-4788 ispartof: location:England status: published

Published
2022

30. Efficacy of Diltiazem to Improve Coronary Vasomotor Dysfunction in ANOCA: The EDIT-CMD Randomized Clinical Trial

Author

Jansen, Tijn P. J., Konst, Regina E., de Vos, Annemiek, Paradies, Valeria, Teerenstra, Steven, van den Oord, Stijn C. H., Dimitriu-Leen, Aukelien, Maas, Angela H. E. M., Smits, Pieter C., Damman, Peter, van Royen, Niels, Elias-Smale, Suzette E., and ACS - Atherosclerosis & ischemic syndromes

Abstract

Background: Diltiazem is recommended and frequently prescribed in patients with angina and nonobstructive coronary artery disease (ANOCA), suspected of coronary vasomotor dysfunction (CVDys). However, studies substantiating its effect is this patient group are lacking. Objectives: The randomized, placebo-controlled EDIT-CMD (Efficacy of Diltiazem to Improve Coronary Microvascular Dysfunction: A Randomized Clinical Trial) evaluated the effect of diltiazem on CVDys, as assessed by repeated coronary function testing (CFT), angina, and quality of life. Methods: A total of 126 patients with ANOCA were included and underwent CFT. CVDys, defined as the presence of vasospasm (after intracoronary acetylcholine provocation) and/or microvascular dysfunction (coronary flow reserve

Published
2022

31. Sex differences in arterial hypertension

Author

Gerdts, Eva, primary, Sudano, Isabella, additional, Brouwers, Sofie, additional, Borghi, Claudio, additional, Bruno, Rosa Maria, additional, Ceconi, Claudio, additional, Cornelissen, Véronique, additional, Diévart, François, additional, Ferrini, Marc, additional, Kahan, Thomas, additional, Løchen, Maja-Lisa, additional, Maas, Angela H E M, additional, Mahfoud, Felix, additional, Mihailidou, Anastasia S, additional, Moholdt, Trine, additional, Parati, Gianfranco, additional, and de Simone, Giovanni, additional

Published
2022
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32. Pregnancy and Spontaneous Coronary Artery Dissection : Lessons From Survivors and Nonsurvivors

Author

Chan, Nathan, Premawardhana, Diluka, Al-Hussaini, Abtehale, Wood, Alice, Bountziouka, Vasiliki, Kotecha, Deevia, Swahn, Eva, Palmefors, Henning, Pagonis, Christos, Sederholm Lawesson, Sofia, Kadziela, Jacek, Garcia-Guimaraes, Marcos, Alfonso, Fernando, Escaned, Javier, Macaya, Fernando, Santas, Melisa, Cerrato, Enrico, Maas, Angela H. E. M., Hlinomaz, Ota, Bogale, Nigussie, Cortese, Bernardo, Cheng, Mavis, Bolger, Aidan, Hussain, Shazia T., Samani, Nilesh J., Knight, Marian, Cauldwell, Matthew, Adlam, David, Chan, Nathan, Premawardhana, Diluka, Al-Hussaini, Abtehale, Wood, Alice, Bountziouka, Vasiliki, Kotecha, Deevia, Swahn, Eva, Palmefors, Henning, Pagonis, Christos, Sederholm Lawesson, Sofia, Kadziela, Jacek, Garcia-Guimaraes, Marcos, Alfonso, Fernando, Escaned, Javier, Macaya, Fernando, Santas, Melisa, Cerrato, Enrico, Maas, Angela H. E. M., Hlinomaz, Ota, Bogale, Nigussie, Cortese, Bernardo, Cheng, Mavis, Bolger, Aidan, Hussain, Shazia T., Samani, Nilesh J., Knight, Marian, Cauldwell, Matthew, and Adlam, David

Abstract

n/a, Funding Agencies|British Heart Foundation [PG/13/96/30608]; National Institute for Health and Care Research rare disease translational collaboration; Leicester National Institute for Health and Care Research Biomedical Research Center; Beat SCAD

Published
2022
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33. Sex differences in arterial hypertension

Author

Gerdts, Eva; https://orcid.org/0000-0003-4109-2311, Sudano, Isabella; https://orcid.org/0000-0001-8197-8892, Brouwers, Sofie; https://orcid.org/0000-0002-7081-4881, Borghi, Claudio; https://orcid.org/0000-0001-8039-8781, Bruno, Rosa Maria; https://orcid.org/0000-0002-6107-3356, Ceconi, Claudio; https://orcid.org/0000-0002-6381-1404, Cornelissen, Véronique; https://orcid.org/0000-0002-0578-4954, Diévart, François; https://orcid.org/0000-0001-6102-8494, Ferrini, Marc; https://orcid.org/0000-0002-2595-2433, Kahan, Thomas; https://orcid.org/0000-0001-9909-4956, Løchen, Maja-Lisa; https://orcid.org/0000-0002-8532-6573, Maas, Angela H E M; https://orcid.org/0000-0001-5782-9926, Mahfoud, Felix; https://orcid.org/0000-0002-4425-549X, Mihailidou, Anastasia S; https://orcid.org/0000-0001-6435-0411, Moholdt, Trine; https://orcid.org/0000-0003-1024-8088, Parati, Gianfranco; https://orcid.org/0000-0001-9402-7439, de Simone, Giovanni; https://orcid.org/0000-0001-8567-9881, Gerdts, Eva; https://orcid.org/0000-0003-4109-2311, Sudano, Isabella; https://orcid.org/0000-0001-8197-8892, Brouwers, Sofie; https://orcid.org/0000-0002-7081-4881, Borghi, Claudio; https://orcid.org/0000-0001-8039-8781, Bruno, Rosa Maria; https://orcid.org/0000-0002-6107-3356, Ceconi, Claudio; https://orcid.org/0000-0002-6381-1404, Cornelissen, Véronique; https://orcid.org/0000-0002-0578-4954, Diévart, François; https://orcid.org/0000-0001-6102-8494, Ferrini, Marc; https://orcid.org/0000-0002-2595-2433, Kahan, Thomas; https://orcid.org/0000-0001-9909-4956, Løchen, Maja-Lisa; https://orcid.org/0000-0002-8532-6573, Maas, Angela H E M; https://orcid.org/0000-0001-5782-9926, Mahfoud, Felix; https://orcid.org/0000-0002-4425-549X, Mihailidou, Anastasia S; https://orcid.org/0000-0001-6435-0411, Moholdt, Trine; https://orcid.org/0000-0003-1024-8088, Parati, Gianfranco; https://orcid.org/0000-0001-9402-7439, and de Simone, Giovanni; https://orcid.org/0000-0001-8567-9881

Abstract

There is strong evidence that sex chromosomes and sex hormones influence blood pressure (BP) regulation, distribution of cardiovascular (CV) risk factors and co-morbidities differentially in females and males with essential arterial hypertension. The risk for CV disease increases at a lower BP level in females than in males, suggesting that sex-specific thresholds for diagnosis of hypertension may be reasonable. However, due to paucity of data, in particularly from specifically designed clinical trials, it is not yet known whether hypertension should be differently managed in females and males, including treatment goals and choice and dosages of antihypertensive drugs. Accordingly, this consensus document was conceived to provide a comprehensive overview of current knowledge on sex differences in essential hypertension including BP development over the life course, development of hypertension, pathophysiologic mechanisms regulating BP, interaction of BP with CV risk factors and co-morbidities, hypertension-mediated organ damage in the heart and the arteries, impact on incident CV disease, and differences in the effect of antihypertensive treatment. The consensus document also highlights areas where focused research is needed to advance sex-specific prevention and management of hypertension.

Published
2022

34. Gender Differences in International Cardiology Guideline Authorship: A Comparison of the US, Canadian, and European Cardiology Guidelines From 2006 to 2020

Author

Rai, Devesh, primary, Kumar, Ashish, additional, Waheed, Syed Hamza, additional, Pandey, Ritambhara, additional, Guerriero, Miranda, additional, Kapoor, Ankita, additional, Tahir, Muhammad Waqas, additional, Zahid, Salman, additional, Hajra, Adrija, additional, Balmer‐Swain, Mallory, additional, Castelletti, Silvia, additional, Maas, Angela H. E. M., additional, Grapsa, Julia, additional, Mulvagh, Sharon, additional, Zieroth, Shelley, additional, Kalra, Ankur, additional, Michos, Erin D., additional, and Gulati, Martha, additional

Published
2022
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35. Future steps in cardio-oncology—a national multidisciplinary survey among healthcare professionals in the Netherlands

Author

Koop, Yvonne, primary, Teske, Arco J., additional, Wanders, Iris, additional, Meijer, Hanneke, additional, Kaanders, J. H. A. M., additional, Manintveld, Olivier C., additional, Hassing, H. Carlijne, additional, Vermeulen, Hester, additional, Maas, Angela H. E. M., additional, van Spronsen, Dick-Johan, additional, Atsma, Femke, additional, and El Messaoudi, Saloua, additional

Published
2022
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40. Association of Salpingectomy With Delayed Oophorectomy Versus Salpingo-oophorectomy With Quality of Life in BRCA1/2 Pathogenic Variant Carriers

Author

Steenbeek, Miranda P., primary, Harmsen, Marline G., additional, Hoogerbrugge, Nicoline, additional, de Jong, Marieke Arts, additional, Maas, Angela H. E. M., additional, Prins, Judith B., additional, Bulten, Johan, additional, Teerenstra, Steven, additional, van Bommel, Majke H. D., additional, van Doorn, Helena C., additional, Mourits, Marian J. E., additional, van Beurden, Marc, additional, Zweemer, Ronald P., additional, Gaarenstroom, Katja N., additional, Slangen, Brigitte F. M., additional, Brood-van Zanten, Monique M. A., additional, Vos, M. Caroline, additional, Piek, Jurgen M. J., additional, van Lonkhuijzen, Luc R. C. W., additional, Apperloo, Mirjam J. A., additional, Coppus, Sjors F. P. J., additional, Massuger, Leon F. A. G., additional, IntHout, Joanna, additional, Hermens, Rosella P. M. G., additional, and de Hullu, Joanne A., additional

Published
2021
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42. Risks and benefits of percutaneous coronary intervention in spontaneous coronary artery dissection

Author

Kotecha, Deevia, primary, Garcia-Guimaraes, Marcos, additional, Premawardhana, Diluka, additional, Pellegrini, Dario, additional, Oliver-Williams, Clare, additional, Bountziouka, Vasiliki, additional, Wood, Alice, additional, Natarajan, Nalin, additional, Jackson, Robert, additional, Chan, Nathan, additional, Ziaullah, Jan, additional, Rakhit, Roby D, additional, Hoole, Stephen P, additional, Johnson, Tom W, additional, Kadziela, Jacek, additional, Ludman, Peter, additional, Samani, Nilesh J, additional, Maas, Angela H E M, additional, van Geuns, Robert-Jan, additional, Alfonso, Fernando, additional, and Adlam, David, additional

Published
2021
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43. An EAPCI expert consensus document on ischaemia with non-obstructive coronary arteries in collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation endorsed by Coronary Vasomotor Disorders International Study Group

Author

Kunadian, Vijay, Chieffo, Alaide, Camici, Paolo G., Berry, Colin, Escaned, Javier, Maas, Angela H E M, Prescott, Eva, Karam, Nicole, Appelman, Yolande, Fraccaro, Chiara, Buchanan, Gill Louise, Manzo-Silberman, Stephane, Al-Lamee, Rasha, Regar, Evelyn, Lansky, Alexandra, Abbott, J. Dawn, Badimon, Lina, Duncker, Dirk J., Mehran, Roxana, Capodanno, Davide, Baumbach, Andreas, Kunadian, Vijay, Chieffo, Alaide, Camici, Paolo G., Berry, Colin, Escaned, Javier, Maas, Angela H E M, Prescott, Eva, Karam, Nicole, Appelman, Yolande, Fraccaro, Chiara, Buchanan, Gill Louise, Manzo-Silberman, Stephane, Al-Lamee, Rasha, Regar, Evelyn, Lansky, Alexandra, Abbott, J. Dawn, Badimon, Lina, Duncker, Dirk J., Mehran, Roxana, Capodanno, Davide, and Baumbach, Andreas

Abstract

This consensus document, a summary of the views of an expert panel organized by the European Association of Percutaneous Cardiovascular Interventions (EAPCI), appraises the importance of ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% of patients undergoing invasive angiography do not have obstructive coronary artery disease, more common in women than in men, and a large proportion have INOCA as a cause of their symptoms. INOCA patients present with a wide spectrum of symptoms and signs that are often misdiagnosed as non-cardiac leading to under-diagnosis/investigation and under-treatment. INOCA can result from heterogeneous mechanism including coronary vasospasm and microvascular dysfunction and is not a benign condition. Compared to asymptomatic individuals, INOCA is associated with increased incidence of cardiovascular events, repeated hospital admissions, as well as impaired quality of life and associated increased health care costs. This consensus document provides a definition of INOCA and guidance to the community on the diagnostic approach and management of INOCA based on existing evidence from research and best available clinical practice; noting gaps in knowledge and potential areas for further investigation.

Published
2021

44. Long-Term Morbidity and Health After Early Menopause Due to Oophorectomy in Women at Increased Risk of Ovarian Cancer: Protocol for a Nationwide Cross-Sectional Study With Prospective Follow-Up (HARMOny Study)

Author

MS Gynaecologische Oncologie, Cancer, Researchgr. Cardiovasculaire Radiologie, Circulatory Health, Genetica Klinische Genetica, Terra, Lara, Hooning, Maartje J, Heemskerk-Gerritsen, Bernadette A M, van Beurden, Marc, Roeters van Lennep, Jeanine E, van Doorn, Helena C, de Hullu, Joanne A, Mom, Constantijne, van Dorst, Eleonora B L, Mourits, Marian J E, Slangen, Brigitte F M, Gaarenstroom, Katja N, Zillikens, M Carola, Leiner, Tim, van der Kolk, Lizet, Collee, Margriet, Wevers, Marijke, Ausems, Margreet G E M, van Engelen, Klaartje, Berger, Lieke Pv, van Asperen, Christi J, Gomez-Garcia, Encarna B, van de Beek, Irma, Rookus, Matti A, Hauptmann, Michael, Bleiker, Eveline M, Schagen, Sanne B, Aaronson, Neil K, Maas, Angela H E M, van Leeuwen, Flora E, MS Gynaecologische Oncologie, Cancer, Researchgr. Cardiovasculaire Radiologie, Circulatory Health, Genetica Klinische Genetica, Terra, Lara, Hooning, Maartje J, Heemskerk-Gerritsen, Bernadette A M, van Beurden, Marc, Roeters van Lennep, Jeanine E, van Doorn, Helena C, de Hullu, Joanne A, Mom, Constantijne, van Dorst, Eleonora B L, Mourits, Marian J E, Slangen, Brigitte F M, Gaarenstroom, Katja N, Zillikens, M Carola, Leiner, Tim, van der Kolk, Lizet, Collee, Margriet, Wevers, Marijke, Ausems, Margreet G E M, van Engelen, Klaartje, Berger, Lieke Pv, van Asperen, Christi J, Gomez-Garcia, Encarna B, van de Beek, Irma, Rookus, Matti A, Hauptmann, Michael, Bleiker, Eveline M, Schagen, Sanne B, Aaronson, Neil K, Maas, Angela H E M, and van Leeuwen, Flora E

Published
2021

47. Cardiovascular health after menopause transition, pregnancy disorders, and other gynaecologic conditions: a consensus document from European cardiologists, gynaecologists, and endocrinologists

Author

Maas, Angela H E M, primary, Rosano, Giuseppe, additional, Cifkova, Renata, additional, Chieffo, Alaide, additional, van Dijken, Dorenda, additional, Hamoda, Haitham, additional, Kunadian, Vijay, additional, Laan, Ellen, additional, Lambrinoudaki, Irene, additional, Maclaran, Kate, additional, Panay, Nick, additional, Stevenson, John C, additional, van Trotsenburg, Mick, additional, and Collins, Peter, additional

Published
2021
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48. ESC Guidelines on the management of cardiovascular diseases during pregnancy: The Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC)

Author

Regitz-Zagrosek, Vera, Blomstrom Lundqvist, Carina, Borghi, Claudio, Cifkova, Renata, Ferreira, Rafael, Foidart, Jean-Michel, Gibbs, J. Simon R., Gohlke-Baerwolf, Christa, Gorenek, Bulent, Iung, Bernard, Kirby, Mike, Maas, Angela H. E. M., Morais, Joao, Nihoyannopoulos, Petros, Pieper, Petronella G., Presbitero, Patrizia, Roos-Hesselink, Jolien W., Schaufelberger, Maria, Seeland, Ute, Torracca, Lucia, Bax, Jeroen, Auricchio, Angelo, Baumgartner, Helmut, Ceconi, Claudio, Dean, Veronica, Deaton, Christi, Fagard, Robert, Funck-Brentano, Christian, Hasdai, David, Hoes, Arno, Knuuti, Juhani, Kolh, Philippe, McDonagh, Theresa, Moulin, Cyril, Poldermans, Don, Popescu, Bogdan A., Reiner, Zeljko, Sechtem, Udo, Sirnes, Per Anton, Torbicki, Adam, Vahanian, Alec, Windecker, Stephan, Baumgartner, Helmut, Deaton, Christi, Aguiar, Carlos, Al-Attar, Nawwar, Garcia, Angeles Alonso, Antoniou, Anna, Coman, Ioan, Elkayam, Uri, Gomez-Sanchez, Miguel Angel, Gotcheva, Nina, Hilfiker-Kleiner, Denise, Kiss, Robert Gabor, Kitsiou, Anastasia, Konings, Karen T. S., Lip, Gregory Y. H., Manolis, Athanasios, Mebaaza, Alexandre, Mintale, Iveta, Morice, Marie-Claude, Mulder, Barbara J., Pasquet, Agnès, Price, Susanna, Priori, Silvia G., Salvador, Maria J., Shotan, Avraham, Silversides, Candice K., Skouby, Sven O., Stein, Jörg-Ingolf, Tornos, Pilar, Vejlstrup, Niels, Walker, Fiona, and Warnes, Carole

Published
2011
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49. Long-Term Morbidity and Health After Early Menopause Due to Oophorectomy in Women at Increased Risk of Ovarian Cancer: Protocol for a Nationwide Cross-Sectional Study With Prospective Follow-Up (HARMOny Study) (Preprint)

Author

Terra, Lara, primary, Hooning, Maartje J, additional, Heemskerk-Gerritsen, Bernadette A M, additional, van Beurden, Marc, additional, Roeters van Lennep, Jeanine E, additional, van Doorn, Helena C, additional, de Hullu, Joanne A, additional, Mom, Constantijne, additional, van Dorst, Eleonora B L, additional, Mourits, Marian J E, additional, Slangen, Brigitte F M, additional, Gaarenstroom, Katja N, additional, Zillikens, M Carola, additional, Leiner, Tim, additional, van der Kolk, Lizet, additional, Collee, Margriet, additional, Wevers, Marijke, additional, Ausems, Margreet G E M, additional, van Engelen, Klaartje, additional, Berger, Lieke PV, additional, van Asperen, Christi J, additional, Gomez-Garcia, Encarna B, additional, van de Beek, Irma, additional, Rookus, Matti A, additional, Hauptmann, Michael, additional, Bleiker, Eveline M, additional, Schagen, Sanne B, additional, Aaronson, Neil K, additional, Maas, Angela H E M, additional, and van Leeuwen, Flora E, additional

Published
2020
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