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Your search keyword '"Ma, Qianquan"' showing total 30 results
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30 results on '"Ma, Qianquan"'

7. Accurate diagnosis and treatment of sacral meningeal cysts without spinal nerve root fibres: identifying leakage orificium using high-resolution spherical arbitrary-dimensional reconstructing magnetic resonance imaging

Author

Yang, Chenlong, primary, Lou, Xiaohui, additional, Huang, Lina, additional, Ma, Qianquan, additional, Yin, Xiaoliang, additional, Zhao, Qiang, additional, Wu, Chao, additional, Wu, Haibo, additional, and Sun, Jianjun, additional

Published
2024
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8. A mathematical model to predict "low-lying" posterior communicating artery aneurysms in neurosurgical practice.

Author

Ma, Qianquan, Liu, Lei, Song, Zhihao, Wen, Hongbo, Li, Kaihuan, Chen, Jingqi, Zhang, Weixin, Huang, Tao, Xu, Yufeng, Li, Haoyu, Lei, Ting, and Sun, Xuezhi

Abstract

"Low-lying" posterior communicating artery (PCoA) aneurysms require great attention in surgical clipping due to their distinct anatomical characteristics. In this study, we propose an easy method to immediately recognize "low-lying" PCoA aneurysms in neurosurgical practice. A total of 89 cases with "low-lying" PCoA aneurysms were retrospectively analyzed. All patients underwent preoperative digital subtraction angiography (DSA) examinations and microsurgical clipping. Cases were classified into the "low-lying" and regular groups based on intraoperative findings. The distance- and angle-relevant parameters that reflected the relative location of the aneurysms and tortuosity of the internal carotid artery were measured using 3D-DSA images. The data were sequentially integrated into a mathematical analysis to obtain the prediction model. Finally, we proposed a novel mathematical formula to preoperatively predict the existence of "low-lying" PCoA aneurysms with great accuracy. Neurosurgeons might benefit from this model, which enables them to directly identify "low-lying" PCoA aneurysms and make appropriate surgical decisions accordingly. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Feasibility and safety of one-stage sacral laminoplasty with autologous sacral laminar reimplantation fixed by absorbable fixation clamps in direct microsurgical treatment of symptomatic sacral extradural spinal meningeal cysts

Author

Yin, Xiaoliang, primary, Zhang, Jia, additional, Ma, Qianquan, additional, Chen, Suhua, additional, Wu, Chao, additional, Yang, Chenlong, additional, Si, Yu, additional, Jiang, Haihui, additional, Guo, Wei, additional, Liu, Ying, additional, Yuan, Huishu, additional, Yang, Jun, additional, and Sun, Jianjun, additional

Published
2023
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18. PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma

Author

Li,Haoyu, Liu,Qing, Xiao,Kai, He,Zhengxi, Wu,Chao, Sun,Jianjun, Chen,Xin, Chen,Suhua, Yang,Jun, Ma,Qianquan, Su,Jun, Li,Haoyu, Liu,Qing, Xiao,Kai, He,Zhengxi, Wu,Chao, Sun,Jianjun, Chen,Xin, Chen,Suhua, Yang,Jun, Ma,Qianquan, and Su,Jun

Abstract

Haoyu Li,1 Qing Liu,1 Kai Xiao,1 Zhengxi He,2 Chao Wu,3 Jianjun Sun,3 Xin Chen,3 Suhua Chen,3 Jun Yang,3 Qianquan Ma,3 Jun Su4 1Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People’s Republic of China; 2Department of Oncology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People’s Republic of China; 3Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing 100191, People’s Republic of China; 4Department of Neurosurgery, Hunan Children’s Hospital, Changsha 410007, Hunan, People’s Republic of ChinaCorrespondence: Qianquan Ma; Jun Su Email mqq0716@live.com; neurodoc_su@126.comPurpose: Gliomas, characterized by aggressiveness and invasiveness, remain incurable after conventional therapies. The molecular mechanisms driving the progression and maintenance of glioma are still poorly understood.Methods: The TCGA and CGGA databases were chosen for bioinformatics analysis. Gene expression profiling interactive analysis (GEPIA) was performed for differential analysis. The Kaplan–Meier method was chosen for survival analysis. Analysis of stromal and immune infiltration was performed using the ESTIMATE algorithm and xCell package. qPCR and Western blotting were performed to measure the expression of PDIA4 at the mRNA and protein levels. IHC was performed to detect the expression of PDIA4 in glioma tissues. The viability of glioma cells was evaluated by the CCK8 assay.Results: In this study, we identified high PDIA4 expression in gliomas that correlated with poor prognosis. The association between IDH1 and different glioma patterns also indicated the potential biological role of PDIA4 in tumor development. Mechanistically, PDIA4 interacted with multiple immunological components to promote an immunosuppressive tumor microenvironment (TME). Knockdown of PDIA4 significantly impaired the proliferation of GBM cells.Conclusi

Published
2021

25. PHF20 Promotes Glioblastoma Cell Malignancies Through a WISP1 / BGN -Dependent Pathway.

Author

Ma, Qianquan, Long, Wenyong, Xing, Changsheng, Jiang, Chongming, Su, Jun, Wang, Helen Y., Liu, Qing, and Wang, Rong-Fu

Subjects
HOMEOBOX proteins, GLIOBLASTOMA multiforme, CANCER invasiveness, STEM cells, CELL proliferation, OLIGODENDROGLIOMAS
Abstract

Glioblastoma (GBM) stem cells are resistant to cancer therapy, and therefore responsible for tumor progression and recurrence after conventional therapy. However, the molecular mechanisms driving the maintenance of stemness and dedifferentiation are poorly understood. In this study, we identified plant homeodomain finger-containing protein 20 (PHF20) as a crucial epigenetic regulator for sustaining the stem cell-like phenotype of GBM. It is highly expressed in GBM and tightly associated with high levels of aggressiveness of tumors and potential poor prognosis in GBM patients. Knockout of PHF20 inhibits GBM cell proliferation, as well as its invasiveness and stem cell-like traits. Mechanistically, PHF20 interacts with WDR5 and binds to the promoter regions of WISP1 for its expression. Subsequently, WISP1 and BGN act in concert to regulate the degradation of β-Catenin. Our findings have identified PHF20 as a key driver of GBM malignant behaviors, and provided a potential target for developing prognosis and therapy. [ABSTRACT FROM AUTHOR]

Published
2020
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29. Analysis on Development Potential of Millettia Specisoa Champ Industry in Guangdong Province

Author

Ma, Shuaipeng, Li, Jing, Long, Weiping, Wei, Shouxing, Tan, Xindao, Ma, Qianquan, and Huang, Bilan

Subjects
Guangdong Province, Development potential, Agribusiness, Millettia specisoa Champ
Abstract

In recent years, Millettia specisoa Champ has attracted extensive attention because of its high medicinal and edible value. This paper will summarize the composition and application of Millettia specisoa Champ, analyze the advantages and existing problems in developing Millettia specisoa Champ industry in Guangdong Province according to the demand for Millettia specisoa Champ and the present situation in Guangdong Province, and put forward reasonable countermeasures and suggestions.

Published
2014
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