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Regarding the rheological properties of fluids, certain nanoparticles can markedly modify the rheological behavior of low surface tension solutions by interacting with surfactant molecules. In this work, a low surface tension fluid with cetyltrimethylammonium chloride was prepared, and the silica nanoparticles were uniformly dispersed into it by ultrasonic dispersion. By adjusting the size, shape, and concentration of nanoparticles, the fluid behavior can be changed from Newtonian to non-Newtonian with finely tuned viscosity and characterized by a shear-thinning rheological behavior. In addition, this work explored how variations in environmental temperature and solution pH affect the rheological responses of the low surface tension suspension system. The experimental findings revealed that increasing the temperature substantially decreases the system's viscosity and induces a shear-thickening behavior. It is particularly significant that, under extreme pH conditions (either strongly acidic or alkaline), the viscosity of the nanoparticle suspensions was markedly enhanced at a particle concentration of 10 000 ppm. This interesting result coincided with a notable reduction in the zeta potential and an increase in the average particle size, suggesting an intensified aggregation of particles within the suspension system. A mechanism detailing the interaction between silica nanoparticles and surfactant micelles was proposed. This work indicates that the incorporation of nanoparticles into surfactant solutions offers a powerful approach to modulating fluid rheology across various conditions. [ABSTRACT FROM AUTHOR]

Aims/Introduction: To investigated the association between serum asprosin and metabolic characteristics in type 2 diabetes mellitus patients with different durations. Materials and Methods: A total of 436 patients with type 2 diabetes mellitus were enrolled in this study from the community health service center in southeastern Shanxi Province. All the patients were divided into two groups according to their diabetes duration: diabetes duration ≤5 years group (n = 132) and diabetes duration ≥10 years group (n = 304). Fasting blood samples were gathered and serum asprosin was tested. Pearson/Spearman correlation analysis was carried out. Results: Asprosin was comparable between the two groups. Asprosin was positively correlated with systolic blood pressure (SBP), triglycerides, creatinine, serum uric acid and low‐density lipoprotein cholesterol in the diabetes duration ≤5 years group (P < 0.05). In the diabetes duration ≥10 years group, asprosin was independently correlated with SBP, diastolic blood pressure, body mass index, total cholesterol, triglycerides, low‐density lipoprotein cholesterol, creatinine, serum uric acid, fasting plasma glucose and glycosylated hemoglobin (P < 0.05). Asprosin was associated with alanine aminotransferase and estimated glomerular filtration rate (P < 0.05). Multiple linear regression analysis found that SBP and diastolic blood pressure is an independent factor related to serum asprosin in the group with diabetes duration ≤5 years (P < 0.05). Fasting plasma glucose, SBP, total cholesterol and serum uric acid is an independent factor related to serum asprosin in the group with diabetes duration ≥10 years (P < 0.05). Conclusions: Serum asprosin was significantly increased in the group with diabetes duration ≥10 years, and glycosylated hemoglobin, blood pressure and estimated glomerular filtration rate were independent risk factors in long‐duration type 2 diabetes mellitus. [ABSTRACT FROM AUTHOR]

Bubbles generated during electrochemical water splitting could adhere to the electrode surface and therefore impede the reaction. Thus, understanding and manipulating the evolution dynamics of bubbles is crucial for enhancing electrolysis efficiency. In this study, we investigated the evolution mechanism and forces acting on individual hydrogen bubble on Pt microelectrode surface by employing different H2SO4 electrolyte concentrations (0.2–1.0 M) under various applied voltages [−2 to −6 V vs saturated calomel electrode (SCE)]. We focused on bubble detachment diameter, average current, and bubble lifetime and subsequently established relational equations over these variables. At −6 V vs SCE, the growth coefficient has a maximum value of 14.42 × 10−4 m/s0.333 when the concentration of electrolyte is around 0.6 M. Gas production at 0.6 M increased by 63.4% compared to 0.2 M and by 11.2% compared to 1.0 M. Therefore, choosing the appropriate electrolyte concentration can maximize gas production and bubble detachment efficiency. Additionally, a force balance model incorporating the Marangoni force for single bubbles on the microelectrode surface was established across varying concentrations of H2SO4 electrolyte. At −4 V vs SCE, the solutal Marangoni force starts to dominate when electrolyte concentrations above 0.4 M. The results demonstrate the critical role of the solutal Marangoni force beyond a certain value of electrolyte concentration. [ABSTRACT FROM AUTHOR]

Enhancing the efficiency of hydrogen production by optimizing gas product transfer within water electrolysis systems is essential. Employing high-speed photography and electrochemical techniques, the entire process of single hydrogen bubble evolution on a Pt microelectrode surface was measured. Results reveal a notable reduction in both bubble detachment radius and growth time with decreasing absolute potential (from −7 to −3 V) and increasing reaction temperature (from 30 °C to 50 °C). Additionally, a comprehensive model estimating bubble coverage on the microelectrode is presented, incorporating bubble radius and current as key influencing factors. This enables an accurate evaluation of mass transfer coefficients during bubble evolution in the absence of forced flow. Furthermore, findings reveal the dominance of bubble-induced micro-convection as the primary mass-transfer mechanism for gas products at high current densities [O (105–106 A/m2)]. The results also indicate that the mass transfer coefficient increases during the inertia-controlled growth stage of bubbles and decreases during the stage controlled by chemical reactions. [ABSTRACT FROM AUTHOR]

Objectives: The lesion distribution of juvenile-onset recurrent respiratory papillomatosis (JORRP) during first-time surgery has been rarely reported. The purpose of this study was to describe the anatomical distribution of papilloma across 25 Derkay sites during initial surgery and to assess the impact of the lesion distribution on disease severity. Methods: Surgical videos and medical records of 106 patients with JORRP (27 aggressive and 79 nonaggressive cases) were retrospectively reviewed. Lesion locations were recorded using Derkay anatomical sites. Logistic regression was used to analyze the effect of the lesion distribution on disease severity. Results: Among the 106 patients, the true vocal cords (90.6% left, 84.0% right) were the most frequently involved site, followed by the false vocal cords (39.6% left, 35.8% right) and the anterior commissure (26.4%). Two patients (1.9%) had tracheal involvement. Patients with false vocal cord involvement (odds ratio [OR] = 3.425, 95% confidence interval [CI] [1.285, 9.132], P =.014) and a younger age at diagnosis (OR =.698, 95% CI [.539,.905], P =.007) were more likely to require more than 4 procedures in the year following first-time surgery. Conclusions: Lesions were most common on the true vocal cords. False vocal cord involvement and a younger age at diagnosis were risk factors for disease severity. [ABSTRACT FROM AUTHOR]

Purpose: To explore the mechanism of insulin secretion dysfunction in pancreatic beta cells induced by N-glycosylation mediated by an infection from the hepatitis C virus (HCV). Methods: Min6 cell models infected with HCV and stimulated with glucose were constructed. Meanwhile, an HCV-infected animal model and a type 2 diabetes mellitus (T2DM) rat model were constructed. Glucose uptake in the Min6 cells was detected, and insulin secretion was detected by ELISA. Flow cytometry, immunofluorescence staining, Western blotting, RT-qPCR, and lectin blotting were used to detect the expression levels of related proteins and mRNA, as well as the level of N-glycosylation. HE staining was used to observe the pathological changes in the pancreatic tissue, and an oral glucose tolerance test (OGTT) was used to evaluate the glucose tolerance of the rats. Results: Compared with the NC group, the expression levels of GnT-IVa, GLUT2, galectin-9, and voltage-dependent calcium channel 1.2 (Cav1.2) were significantly downregulated in the HCV-infected group. The ATP-sensitive potassium channel (KATP) component proteins SUR1 and Kir6.2 were significantly upregulated, while intracellular glucose intake and insulin secretion decreased, N-glycosylation levels and ATP levels significantly decreased, and the overexpression of GnT-IVa reversed the effect of the HCV infection. However, treatment with the glycosylation inhibitor kifunensine (KIF) or the KATP channel activator diazine (Dia) reversed the effects of the overexpression of GnT-IVa. In the animal experiments, HE staining revealed serious pathological injuries in the pancreatic tissue of the HCV-infected rats, with decreased glucose tolerance and glycosylation levels, decreased insulin secretion, downregulated expression of GnT-IVa, GLUT2, and Cav1.2, and upregulated expression of SUR1 and Kir6.2. The overexpression treatment of GnT-IVa or the KATP channel antagonist miglinide reversed the effects of HCV. Conclusion: HCV infection inhibits GLUT2 N-glycosylation on the pancreatic β cell surface by downregulating the expression of GnT-IVa and then activates the KATP pathway, which ultimately leads to disturbances in insulin secretion. [ABSTRACT FROM AUTHOR]

Past research on the Investment Model of Commitment suggests that satisfaction, quality of alternatives, and investment consistently predict commitment levels in romantic relationships. Previous research examining the Investment Model has focused on allosexual and alloromantic populations – i.e. individuals who experience sexual and romantic attraction, respectively. We extended this research to asexual and aromantic individuals. Asexual and aromantic participants in relationships completed the four Investment Model subscales (i.e. satisfaction, investments, quality of alternatives, commitment). A confirmatory factor analysis (CFA) showed that the model fit to the original Investment Model factors was poor. An exploratory factor analysis (EFA) revealed that the investments and quality of alternatives items mostly loaded on the original factors; however, satisfaction items and commitment items mostly loaded on the same factor. These results suggest that asexual and aromantic individuals may not distinguish between relationship satisfaction and commitment, or individuals may have relatively equal amounts of satisfaction and commitment in their relationships. In addition, many asexual and aromantic individuals practice non-monogamous relationships, and have a higher quality of alternatives than those who practice monogamous relationships. Ultimately, the findings could guide practitioners when working with asexual and aromantic individuals as well as future research focusing on these populations. [ABSTRACT FROM AUTHOR]

Disclosing personal feelings could reduce stress during a difficult time, such as the COVID‐19 pandemic. The current study examined the linear and curvilinear relationships between willingness to self‐disclose to a romantic partner and COVID stress. Participants completed questionnaires online regarding willingness to self‐disclose, COVID stress, relationship factors, and self‐esteem. Results showed a marginally significant inverted U‐shaped curvilinear relationship between willingness to self‐disclose and COVID stress, suggesting the trend that individuals who were willing to self‐disclose at a low or high level had lower COVID stress compared to individuals who were willing to self‐disclose at a medium level. This relationship was mediated by commitment and self‐esteem. Future research could examine the impact of self‐disclosure on COVID stress using an experimental or longitudinal design. [ABSTRACT FROM AUTHOR]

The Two-Dimensional Model of Relational Self-change (TDM) suggests four types of self-change that may be elicited by romantic relationships: self-expansion, self-adulteration, self-pruning, and self-contraction. Previous research has shown that these four types of relational self-change were associated with relational outcomes. Prior research has also shown that positive illusions and expectations in romantic relationships can lead to positive relational outcomes. The current study used a longitudinal design to investigate how the four types of expected relational self-change affect future relationship satisfaction and commitment. Results indicated that participants had higher expected self-changes than their actual self-changes after three months, but their expected self-changes and actual self-changes were correlated. At Time 1 of their relationship, participants' relationship satisfaction and commitment were related to their expected self-changes. However, controlling for Time 1 relationship satisfaction and commitment, expected self-changes predicted commitment, but not relationship satisfaction, three months later. [ABSTRACT FROM AUTHOR]

Understanding and controlling hydrogen bubble growth and detachment during water electrolysis is crucial for improving its efficiency. This study investigates bubble dynamics for hydrogen evolution on a platinum microelectrode in an acidic electrolyte with different gas/electrolyte surface tensions by adding varying surfactant concentrations. Three hydrogen bubble evolution patterns were observed: periodic detachment of individual bubbles at low surfactant concentrations of 0 and 1 × 10−7 M, respectively; one or two small bubbles are formed at the foot of the bubble during the evolution of single main bubble at intermediate surfactant concentrations of 1 × 10−6 and 1 × 10−5 M; and periodic detachment of large bubbles with aperiodic release of tiny bubbles at higher surfactant concentrations of 1 × 10−4 M. The concentration Marangoni force on individual H2 bubbles decreases significantly with surfactant concentration. This results in shorter evolution cycles from 138.12 to 6.98 s at −0.6 V vs the saturated calomel electrode, reduced detachment radii from 765.95 to 359.54 μm at −0.6 VSCE, and accelerated hydrogen bubble growth. This finding offers a new way to control bubble dynamics during electrochemical bubble formation. [ABSTRACT FROM AUTHOR]