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Metasurface has the ability to flexibly modulate the wavefront and detect the polarization states, thus receiving widespread research attention. The combination of polarization multiplexing techniques and focused beams with polarization information provides a new approach to compact polarization detection behavior. Here, an all-dielectric metasurface based on polarization multiplexing encoding technique is demonstrated and assigns the independent phase distributions to x- and y-polarized channels to separate different polarized components. Combining Stokes parameters and visualized polarization ellipses, realizing one-to-one mapping of the incident polarization states with far-field images. We obtain the Poincaré sphere and visualized polarization ellipses based on Stokes parameters to verify the polarization detection ability of the designed metasurface. The proposed scheme is expected to provide potential applications in fields such as full-Stokes polarization detection, high-resolution imaging, and terahertz communication. [ABSTRACT FROM AUTHOR]

Cosmic microwave background (CMB) experiments have deployed focal planes with O(104) transition edge sensor (TES) bolometers cooled to sub-Kelvin temperatures by multiplexing the readout of many TES channels onto a single pair of wires. Digital Frequency-domain Multiplexing (DfMux) is a multiplexing technique used in many CMB polarization experiments, such as the Simons Array, SPT-3 G, and EBEX. The DfMux system studied here uses LC filters with resonant frequencies ranging from 1.5 to 4.5 MHz connected to an array of TESs. Each detector has an amplitude-modulated carrier tone at the resonant frequency of its accompanying LC resonator. The signal is recovered via quadrature demodulation where the in-phase (I) component of the demodulated current is in phase with the complex admittance of the circuit and the quadrature (Q) component is orthogonal to I. Observed excess current noise in the Q component is consistent with fluctuations in the resonant frequency. This noise has been shown to be non-orthogonal to the phase of the detector's responsivity. We present a detailed analysis of the phase of responsivity of the TES and noise sources in our DfMux readout system. Further, we investigate how modifications to the TES operating resistance and bias frequency can affect the phase of noise relative to the phase of the detector responsivity, using data from Simons Array to evaluate our predictions. We find that both the phase of responsivity and phase of noise are functions of the two tuning parameters, which can be purposefully selected to maximize signal-to-noise (SNR) ratio.

Orbital angular momentum (OAM) multiplexing/demultiplexing technology is crucial in increasing the data transmission rate for acoustic communication. However, the existing acoustic OAM multiplexing/demultiplexing is still limited to eight channels, and its combination with other communication techniques has not been verified experimentally. Here, we experimentally demonstrate the demultiplexing of up to 40 data channels using OAM multiplexing combined with wavelength-division multiplexing (WDM). The proposed demultiplexing method is improved from the virtual rotating receiver method used to detect the rotational Doppler effect of the OAM waves by a static array of microphones. The improved method has overcome the challenges of insufficient response, cross-talk, and signal aliasing, which often hinder the existing demultiplexing methods in the low-frequency region. The proposed demultiplexing method can be used to quickly decode the massive information concealed in a large number of acoustic OAM-WDM channels. Our work also shows practical prospects in underwater communication applications, especially in long-range communication using acoustic waves at low frequencies. [ABSTRACT FROM AUTHOR]

The stochastic block model (SBM) is a probabilistic model aimed at clustering individuals within a simple network based on their social behavior. This network consists of individuals and edges representing the presence or absence of relationships between each pair of individuals. This paper aims to extend the traditional stochastic block model to accommodate multiplex weighted nodes networks. These networks are characterized by multiple relationship types occurring simultaneously among network individuals, with each individual associated with a weight representing its influence in the network. We introduce an inference method utilizing a variational expectation-maximization algorithm to estimate model parameters and classify individuals. Finally, we demonstrate the effectiveness of our approach through applications using simulated and real data, highlighting its main characteristics. [ABSTRACT FROM AUTHOR]

The peak-to-average power ratio (PAPR), commonly used to describe the amplitude variations of an OFDM (orthogonal frequency-division multiplex) signal, does not accurately reflect its impact on the system performance. This paper applies the mutual information as a metric to assess the effects of nonlinear PAPR reduction schemes on the performance of OFDM systems. Evaluation of the achieved mutual information shows that a significant capacity loss from clipping occurs only at high SNR (signal-to-noise ratio) and a simple compression/expansion technique is proposed to achieve close to optimal performance in this regime. The effectiveness of this method is validated through WER (word error rate) simulations with several modulation and coding schemes. [ABSTRACT FROM AUTHOR]

Core–periphery detection aims to separate the nodes of a complex network into two subsets: a core that is densely connected to the entire network and a periphery that is densely connected to the core but sparsely connected internally. The definition of core–periphery structure in multiplex networks that record different types of interactions between the same set of nodes on different layers is non-trivial since a node may belong to the core in some layers and to the periphery in others. We propose a nonlinear spectral method for multiplex networks that simultaneously optimizes a node and a layer coreness vector by maximizing a suitable non-convex homogeneous objective function by a provably convergent alternating fixed-point iteration. We derive a quantitative measure for the quality of a given multiplex core–periphery structure that allows the determination of the optimal core size. Numerical experiments on synthetic and real-world networks illustrate that our approach is robust against noisy layers and significantly outperforms baseline methods while improving the latter with our novel optimized layer coreness weights. As the runtime of our method depends linearly on the number of edges of the network, it is scalable to large-scale multiplex networks. [ABSTRACT FROM AUTHOR]

The waveguide‐integrated metasurface introduces a novel photonic chip capable of converting guided modes into free‐space light. This enables functions such as off‐chip beam focusing, steering, and imaging. The challenge lies in achieving hyper‐multiplexing across diverse parameters, including guided‐wave mode type, direction, polarization, and notably, multiple wavelengths. Here, a comprehensive end‐to‐end inverse design framework is introduced, rooted in a physical model, for the multifunctional design of on‐chip metasurfaces. This framework allows for metasurface optimization through a target‐field‐driven iteration process. A hypermultiplexed on‐chip metasurface capable of generating red‐green‐blue holograms at multiple target planes is demonstrated, with both independent and cooperative control over guided‐wave direction. Significantly, the proposed method streamlines the design process utilizing only the positions of meta‐atoms as the design variable. Nine independent holographic channels are demonstrated through a combination of wavelength and distance multiplexing. Moreover, by incorporating the excitation direction into the design, the metasurface produces a total of 36 distinct holograms. The robustness of these results against fabrication discrepancies is validated through 3D full‐wave electromagnetic simulations, aligning well with advanced manufacturing techniques. The research presents a universal design framework for the development of multifunctional on‐chip metasurfaces, opening up new avenues for a wide range of applications. [ABSTRACT FROM AUTHOR]

Fluorescence microscopy has long been a transformative technique in biological sciences. Nevertheless, most implementations are limited to a few targets, which have been revealed using primary antibodies and fluorescently conjugated secondary antibodies. Super-resolution techniques such as Exchange-PAINT and, more recently, SUM-PAINT have increased multiplexing capabilities, but they require specialized equipment, software, and knowledge. To enable multiplexing for any imaging technique in any laboratory, we developed NanoPlex, a streamlined method based on conventional antibodies revealed by engineered secondary nanobodies that allow the selective removal of fluorescence signals. We develop three complementary signal removal strategies: OptoPlex (light-induced), EnzyPlex (enzymatic), and ChemiPlex (chemical). We showcase NanoPlex reaching 21 targets for 3D confocal analyses and 5–8 targets for dSTORM and STED super-resolution imaging. NanoPlex has the potential to revolutionize multi-target fluorescent imaging methods, potentially redefining the multiplexing capabilities of antibody-based assays. Confocal and super-resolution tools used for multiplexed fluorescence imaging often demand specialized equipment and software. Here, the authors present NanoPlex, a universal method for high-plex labeling while preserving cellular ultrastructure. The approach relies on engineered secondary nanobodies that allow the selective removal of fluorescence signals. [ABSTRACT FROM AUTHOR]

A one-grating common-path phase-shifting interferometer for quantitative phase imaging is proposed as an improvement over the original interferometer design. In the original version, the setup is long, involving a grating pair, and requires precise mechanical translation of the grating, which poses difficulties for practical applications. The proposed interferometer utilizes grating multiplexing to reduce the length of the optical setup and uses a phase-only spatial light modulator to implement pinhole filtering and phase shifting simultaneously without any moving parts, making it more conducive for the realization of a practical version. [ABSTRACT FROM AUTHOR]

Computational imaging, as a novel technology utilizing encoded image acquisition, relies on intelligent decoding methods for effective image restoration and sensing. Optical computing‐based decoders can efficiently process and extract features from pre‐sensor information, reducing the computational burden on digital computers. However, mainstream parallel optical neural network (ONN) architectures based on wavefront propagation typically possess complex network structures and high‐precision parameters, which pose challenges in terms of precise fabrication and system calibration, as well as sensitivity to signal‐to‐noise ratios. In this work, a binary‐weighted optical computing engine is proposed with spatial multiplexing and aggregation (B‐OSMA), a large‐scale passive ONN implementation that achieves high‐efficiency image sensing. Employing B‐OSMA as an optical decoder, demonstrated image categorizing from 2% compressive is experimented sampling with 92.0% and 83.8% accuracy on MNIST and fashion‐MNIST datasets, respectively, approaching the performance of full‐precision electronic computing while reducing storage requirements by 97%. Compared to conventional ONNs with analog weights, the B‐OSMA exhibits enhanced resilience against systematic errors and ambient noise. This work represents a significant advancement towards practical applications of optical computing in image sensing. [ABSTRACT FROM AUTHOR]

Accurate full‐parameter construction of the Jones matrix is of great significance for encoding multiple functions in a single metasurface. Supercells composed of several elements are used for this purpose through coherent superposition. But all the elements in the reported studies should be lossless with near‐unity transmission, which limits the material system and restricts the Jones matrix construction in a unitary manner. Here a non‐unitary matrix decomposition method is proposed to build the supercell using a pair of 0°‐oriented rods and a pair of 45°‐oriented rods for on‐demand design of arbitrary symmetric Jones matrices. This method is applicable for lossy metasurfaces and offers straightforward physical guidance for structure design without optimization. The accuracy of the on‐demand Jones matrix generation is demonstrated by several 3D‐printed alumina metalenses with 3‐, 4‐, and 6‐channel polarization‐multiplexed focusing. The study opens a new pathway for non‐silicon meta‐optics and holds great potential for dynamic or switchable applications. [ABSTRACT FROM AUTHOR]

In the context of locomotive traction systems, the power electronic traction transformer (PETT) represents a pivotal component, fulfilling essential functions pertaining to electrical isolation and power control. The majority of existing PETT prototypes employ a combination of a cascade structure and an ISOP structure. The aforementioned scheme effectively reduces the voltage withstand level of the power devices on the input side, yet it also necessitates the utilisation of a greater number of power devices and passive components within the PETT. In order to further reduce the number of power devices used, this paper proposes a new cascaded PETT design. The proposed PETT will adopt a scheme combining a cascade structure and a hardware circuit multiplexing. This paper first analyses the operation principle of the new circuit under non-single frequency PWM control. It then derives the design equations for some hardware parameters and control circuits. Finally, it verifies the effectiveness of the proposed PETT through simulation analysis. [ABSTRACT FROM AUTHOR]

Although orbital angular momentum (OAM) is extensively explored and researched in various scientific domains, its practical application in wireless communications still faces numerous challenges. Notably, existing OAM beam generation technologies need to meet the diversified demands of modern wireless communication, such as miniaturization, cost‐effectiveness, and system integration. Driven by the immense potential of OAM in communication systems, in this work, an innovative method based on leaky cables capable of simultaneously generating multiple vortex beams, overcoming a series of implementation issues associated with multiplexing emitters, is introduced. A design prototype is fabricated and tested, and the measurement results align closely with the simulations, validating the multifunctionality and practicality of the method. Moreover, the proposed strategy can seamlessly extend to optical frequencies using the concept of leaky fibers. In this method, not only efficient spatial utilization and excellent isolation are realized but also high cost‐effectiveness is possessed. Compared to previous strategies, this technique may have an impact on simplifying the establishment of communication system platforms based on OAM multiplexing. [ABSTRACT FROM AUTHOR]

Radio over fiber (ROF) is a very attractive technology for the increasing demand for flexibility and transmission capacity and due to its high bandwidth and low attenuation, it offers an economic advantage. The wavelength division multiplexing (WDM) is used to multiplex the different wavelengths signals within a single optical fiber. In this paper, WDM-ROF system is analysed with different filters using an optisystem. Results were compared using max Q factor, min BER, and eye height parameters. [ABSTRACT FROM AUTHOR]

In this paper, we have designed and presented a simulation analysis of 96 × 40 Gbps CSRZ based DWDM long-haul transmission system under the influence of Kerr non-linearities using hybrid dispersion compensation technique. The proposed system performance is measured at 50 GHz channel spacing in terms of BER, Q-factor and eye-diagram for the varied launched power ranging from −4 dB m to 12 dB m of CW laser array and various transmission distances. We have implemented pre-filtering before multiplexing the modulated data of all the channels and post-filtering after de-multiplexing for avoiding co-channel interference and to suppress the cross-talk. By optimizing the system parameters, the transmission distance of 16,500 km is achieved for BER value of 1.48,875E-14 with corresponding Q-factor value of 7.55,989 at 6 dB m input power. The CSRZ modulated system has shown much robustness against the occurred linear and non-linear degradation factors due to its narrow spectrum. [ABSTRACT FROM AUTHOR]

In this paper, the proficiency of nonlinearity compensation studied on the polarization division multiplexing 0.3 return-to-zero quadrature phase-shift keying (PDM-0.3RZ-QAM) coherent optical system. The considerable nonlinear effect is the self-phase modulation (SPM) in the presence of chromatic dispersion. The nonlinearity mitigation technique based on the digital backpropagation (DBP) algorithm is implemented on the receiver side. The performance of the system was investigated in different terms as the optical signal-noise ratio, bit error rate, and the maximum transmission distance. The results demonstrated that the penalties were decreased by 3 dB. The maximum achievable distance was extended to 2000 km. [ABSTRACT FROM AUTHOR]

To achieve the best performance in terms of accuracy and complexity of massive multiple-input multiple-output (Massive MIMO) in wireless communication systems, hybrid beamforming (HBF) is a promising technique that provides high data rate multiplexing gains and enhances the spectral efficiency (SE) of the system. In this paper, a novel received signal strength indicator (RSSI) method is proposed to design an HBF for Massive MIMO BF via multitasking deep learning (DL) that minimizes the reliance on the channel state information (CSI) feedback. The trade-off between the enhancement SE of the system and the deep neural networks (DNNs) performance is optimized, and the results reveal that the proposed novel DL techniques achieve predicted spectral efficiencies with accuracy of 99.23% and 95.64% for Deep-HBF and Deep-AFP, respectively. The processing times for Deep-HBF and Deep-AFP are 709.2914 sec and 1425.864 sec, respectively. Notably, Deep-AFP exhibits a higher range of computational complexity compared to Deep-HBF. It is worth mentioning that the proposed techniques utilize the same DNN architecture. [ABSTRACT FROM AUTHOR]

Routing and multiplexing of the optical surface waves are critical for the ultra‐compact nano‐photonic systems. Given this background, traditional metal‐based systems, despite of the ability of supporting the surface plasmon polariton propagation, are constrained on manipulations due to the optical isotropy, and artificially designed structures are always required at the input or output to help attain the additional selectivity. Here, a spin‐dependent multi‐channel scheme is proposed based on the modulation ability of the hyperbolic metamaterial's anisotropy on Dyakonov Surface Waves. The input coupling, propagation direction, as well as the output coupling of the optical single are well determined by the certain spin feature carried by the light and the orientation of the interface's anisotropy because of the spin‐momentum locking. Specially, by constructing a twinning hyperbolic metamaterial, which contains the structural symmetry and materials symmetry, a photonic chip with 4 routing channels are demonstrated experimentally, where the spin of an incident beam can be maintained during the propagation on‐chip and then delivered back into the free space, offering a new planar scheme for metamaterial‐based spin‐controlled nano‐photonic applications. [ABSTRACT FROM AUTHOR]

Steganography is a technique that encrypts information by hiding it in another medium, such as video, audio, images, and text. The principal purpose of steganography is to conceal the existence of information so that it cannot be easily recognized by a third-party during transmission, which guarantees information security. Surface-enhanced Raman scattering (SERS) probes contain rich spectral information. With the increasing application of SERS in optical anticounterfeiting field, the development of SERS labels with superior encoding capacity has become research hotspot. In this study, we mixed Au nanostar SERS probes with ordinary commercial ink to obtain SERS ink for optical steganography and anticounterfeiting labels. Au nanostars have abundant tip "hotspots" and large specific surface area, and strong SERS signals can be manufactured by modifying Raman molecules on its surface. Fifteen different kinds of Raman molecules were chosen as a demonstration, and the signal molecules were tightly modified on the surface of Au nanostars by dopamine encapsulation and then mixed with ordinary ink to obtain SERS ink with different signals. Then, the information recorded by SERS ink was extracted and interpreted by a micro-Raman imaging system. In addition, SERS ink can also be used in barcodes and quick response (QR) codes, and the possibility of being cracked can be greatly reduced through Raman signal multiplexing. Due to the advantages of SERS ink, such as simple preparation, good photostability, long-term stability, multiplexing steganography, and convenient use, we believe that Au nanostar-based SERS ink has broad prospects in the application of optical steganography and anticounterfeiting. [ABSTRACT FROM AUTHOR]

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A multiplex, delay‐and‐sum (MDAS) architecture is proposed to implement a fixed‐focus receive beamformer such as the first stage of the synthetic aperture sequential beamforming (P‐SASB) and synthetic transmit beams combined with the P‐SASB (STB‐P‐SASB) beamforming methods. The output image of this architecture has a resolution and contrast‐to‐noise ratio (CNR) almost similar to that of the delay‐and‐sum (DAS) architecture. In the analog part of this architecture, there is no need to use any analog memory and in the digital part, the need to use high‐speed memories and interpolation filter is eliminated. In this architecture for each input channel, the power consumption in the mixed‐signal part is increased by approximately 1.14 mW in comparison to that of the DAS architecture. On the other hand, due to the elimination of the power consumption related to the interpolation filter in the digital part, the total power consumption of the MDAS architecture increases by a maximum of 9.2% compared to the DAS architecture. Also, the silicon area required to implement the mixed‐signal part of the MDAS architecture when implementing the first stage of P‐SASB and STB‐P‐SASB beamforming methods is reduced by about 3 times and increased by a maximum of 25%, respectively, compared to that of the DAS architecture. [ABSTRACT FROM AUTHOR]

Entangled multiphoton sources are essential for both fundamental tests of quantum foundations and building blocks of contemporary optical quantum technologies. While efforts over the past three decades have focused on creating multiphoton entanglement through multiplexing existing biphoton sources with linear optics and postselections, our work presents a groundbreaking approach. We observe genuine continuous-mode time-energy-entangled W-class triphotons with an unprecedented production rate directly generated through spontaneous six-wave mixing (SSWM) in a four-level triple-Λ atomic vapor cell. Using electromagnetically induced transparency and coherence control, our SSWM scheme allows versatile narrowband triphoton generation with advantageous properties, including long temporal coherence and controllable waveforms. This advancement is ideal for applications like long-distance quantum communications and information processing, bridging single photons and neutral atoms. Most importantly, our work establishes a reliable and efficient genuine triphoton source, facilitating accessible research on multiphoton entanglement. [ABSTRACT FROM AUTHOR]

Harmonic generation and utilization are significant topics in nonlinear science. Although the progress in the microwave region has been expedited by the development of time‐modulated metasurfaces, one major issue of these devices is the strong entanglement of multiple harmonics, leading to criticism of their use in frequency‐division multiplexing (FDM) applications. Previous studies have attempted to overcome this limitation, but they suffer from designing complexity or insufficient controlling capability. Here a new space‐time‐coding metasurface (STCM) is proposed to independently and precisely synthesize not only the phases but also the amplitudes of various harmonics. This promising feature is successfully demonstrated in wireless space‐ and frequency‐division multiplexing experiments, where modulated and unmodulated signals are simultaneously transmitted via different harmonics using a shared STCM. To illustrate the advantages, binary frequency shift keying (BFSK) and quadrature phase shift keying (QPSK) modulation schemes are respectively implemented. Behind the intriguing functionality, the mechanism of the space‐time coding strategy and the analytical designing method are elaborated, which are validated numerically and experimentally. It is believed that the achievements can potentially propel the time‐vary metasurfaces in the next‐generation wireless applications. [ABSTRACT FROM AUTHOR]

DNA methylation biomarkers have emerged as promising tools for cancer detection. Common methylation patterns across tumor types allow multi‐cancer detection. Droplet digital PCR (ddPCR) has gained considerable attention for methylation detection. However, multi‐cancer detection using multiple targets in ddPCR has never been performed before. Therefore, we developed a multiplex ddPCR assay for multi‐cancer detection. Based on previous data analyses using The Cancer Genome Atlas (TCGA), we selected differentially methylated targets for eight frequent tumor types (lung, breast, colorectal, prostate, pancreatic, head and neck, liver, and esophageal cancer). Three targets were validated using ddPCR in 103 tumor and 109 normal adjacent fresh frozen samples. Two distinct ddPCR assays were successfully developed. Output data from both assays is combined to obtain a read‐out from the three targets together. Our overall ddPCR assay has a cross‐validated area under the curve (cvAUC) of 0.948. Performance between distinct cancer types varies, with sensitivities ranging from 53.8% to 100% and specificities ranging from 80% to 100%. Compared to previously published single‐target parameters, we show that combining targets can drastically increase sensitivity and specificity, while lowering DNA input. In conclusion, we are the first to report a multi‐cancer methylation ddPCR assay, which allows for highly accurate tumor predictions. [ABSTRACT FROM AUTHOR]

Mode‐division multiplexing (MDM) technology, as a new way to increase the communication capacity of a single wavelength carrier, has attracted increasing attention. As a fundamental building block for MDM communication systems, multimode optical switch is playing an important role for routing the increasingly complex network. However, it is still very challenging to achieve a multimode optical switch with high flexibility and low power‐consumption in a large bandwidth. Here, a 1 × 2 dual‐mode optical switch is proposed and experimentally demonstrated, where the E11 and E21 modes can be switched output from either of the two output ports simultaneously or individually with low power‐consumption. For the proposed dual‐mode optical switch, three asymmetric Y‐junctions are used as mode (de)multiplexers, two Mach–Zehnder interferometers form a single‐mode switch matrix, and a 2 × 2 multimode interferometer is used as the waveguide crossing. The device is fabricated with simple photolithography and wet‐etching methods. The measurement results show that the driving powers of the device are lower than 8.4 mW, and the crosstalks are less than −12.4 dB in the wavelength range of 1500–1600 nm. By implementing the dynamic control of resources between the guided modes, the proposed device can greatly improve the flexibility and efficiency of reconfigurable MDM networks. [ABSTRACT FROM AUTHOR]

Optical wireless communication (OWC) stands out as one of the most promising technologies in the sixth-generation (6G) mobile networks. The establishment of high-quality optical links between transmitters and receivers plays a crucial role in OWC performances. Here, by a compact beam splitter composed of a metasurface and a fiber array, we proposed a wide-angle (~120°) OWC optical link scheme that can parallelly support up to 144 communication users. Utilizing high-speed optical module sources and wavelength division multiplexing technique, we demonstrated each user can achieve a communication speed of 200 Gbps which enables the entire system to support ultra-high communication capacity exceeding 28 Tbps. Furthermore, utilizing the metasurface polarization multiplexing, we implemented a full range wide-angle OWC without blind area nor crosstalk among users. Our OWC scheme simultaneously possesses the advantages of high-speed, wide communication area and multi-user parallel communications, paving the way for revolutionary high-performance OWC in the future. In this work, the authors present a metasurface-based wide-angle beam splitter designed for future applications in optical wireless communication. By leveraging the metasurface polarization multiplexing and wavelength division multiplexing properties, they achieved a high-performance optical wireless communication system, possessing a Tbps communication rate, more than 120° coverage range, and up to 144 users parallel communication capabilities. [ABSTRACT FROM AUTHOR]

Multiplexing technology creates several orthogonal data channels and dimensions for high‐density information encoding and is irreplaceable in large‐capacity information storage, and communication, etc. The multiplexing dimensions are constructed by light attributes and spatial dimensions. However, limited by the degree of freedom of interaction between light and material structure parameters, the multiplexing dimension exploitation method is still confused. Herein, a 7D Spin‐multiplexing technique is proposed. Spin structures with four independent attributes (color center type, spin axis, spatial distribution, and dipole direction) are constructed as coding basic units. Based on the four independent spin physical effects, the corresponding photoluminescence wavelength, magnetic field, microwave, and polarization are created into four orthogonal multiplexing dimensions. Combined with the 3D of space, a 7D multiplexing method is established, which possesses the highest dimension number compared with 6 dimensions in the previous study. The basic spin unit is prepared by a self‐developed laser‐induced manufacturing process. The free state information of spin is read out by four physical quantities. Based on the multiple dimensions, the information is highly dynamically multiplexed to enhance information storage efficiency. Moreover, the high‐dynamic in situ image encryption/marking is demonstrated. It implies a new paradigm for ultra‐high‐capacity storage and real‐time encryption. [ABSTRACT FROM AUTHOR]

Mode converters (MCs) play an essential role in mode-division multiplexing (MDM) systems. Numerous schemes have been developed on the silicon-on-insulator (SOI) platform, yet most of them focus solely on the conversion of fundamental mode to one or two specific higher-order modes. In this study, we introduce a hybrid shape optimization (HSO) method that combines particle swarm optimization (PSO) with adjoint methods to optimize the shape of the S-bend waveguide, facilitating the design of arbitrary-order MCs featuring compactness and high performance. Our approach was validated by designing a series of 13 μm-long MCs, enabling efficient conversion between various TE modes, ranging from TE0 to TE3. These devices can be fabricated in a single lithography step and exhibit robust fabrication tolerances. Experiment results indicate that these converters achieve low insertion losses under 1 dB and crosstalks below −15 dB across bandwidths of 80 nm (TE0–TE1), 62 nm (TE0–TE2), 70 nm (TE0–TE3), 80 nm (TE1–TE2), 55 nm (TE1–TE3), and 75 nm (TE2–TE3). This advancement paves the way for flexible mode conversion, significantly enhancing the versatility of on-chip MDM technologies. [ABSTRACT FROM AUTHOR]

The expression profiles of intracellular biomarkers hold significance for understanding cellular biological functions and tracking pathological activities. Due to its programmability and biocompatibility, extensive efforts have been devoted to design various kinds of nucleic acid probes for biomarker detection. However, pinpointing a single biomarker could end up in a false positive signal, delaying diagnosis. In this review, we present an overview of current advances in biomarker detection and signal amplification techniques. We highlight strategies for biomarker multiplexing and signal amplification with combination of isothermal approaches. High specificity and sensitivity are the two criteria for a desired probe, as are the challenges encountered by a probe that operates efficiently in biological systems. With higher biomarker identification accuracy, we may be able to move one step closer to precision medicine. [ABSTRACT FROM AUTHOR]

Polarization is the nature of optics. Exploiting metasurface's polarizations can enhance the multiplexing capacity but face a limited number of channels. For example, a single‐layer metasurface can offer three independent channels with six degrees of freedom (DoFs) including the amplitude and phase of Ex, Exy(yx), and Ey of the Jones matrix. In this work, it is theoretically demonstrated that the degrees of freedom of dual‐layer metasurfaces can reach eight, overcoming the polarization multiplexing constraints of single‐layer metasurfaces and that the cross‐talk can be largely reduced as compared with single‐layer metasurfaces when the channel number is larger than three. Numerical calculations manifest a decrease of 100%, 63%, and 50% for the cross‐talk of channels 4, 5, and 6, respectively. As a proof‐of‐concept demonstration of high‐capacity polarization multiplexing, an arbitrary‐polarization‐controlled 5‐channel dual‐layer metasurface exhibiting five nanoprintings and five holographic images with reduced cross‐talk under different incident and output polarizations is successfully designed. Thus, the research highlighting the high‐multiplexing‐capacity of dual‐layer metasurfaces can significantly advance multifunctional optical devices with high efficiency, simple integration, and ease of manipulation. [ABSTRACT FROM AUTHOR]

As a powerful platform for next‐generation display, planar liquid crystal (LC) optics exhibit attractive properties such as electro‐optical response, high efficiency, and broadband tunability. With planar LC optics applications taking off, multidimensional modulation and multiplexing capability of light wave is becoming crucial. Here, a Pancharatnam‐Berry phase LC hologram is demonstrated that enables the multidimensional modulation of amplitude, phase, and polarization of light, which increases the degree of freedom of multiplexing display to 4 at a single wavelength, realizing the simultaneous decoupling modulation in dual polarization channels in near and far fields. According to the quaternary degeneracy characteristics of the orientation angle of LC molecules implied in Malus' law, the LC holograms are designed using the optimized Gerchberg‐Saxton and annealing algorithms, and it is demonstrated that the spatial and polarization multiplexing of LC holograms have remarkable wavelength‐dependent electrical tunability. This LC hologram paves a promising pathway toward multifunctional LC optics for advanced display and imaging. [ABSTRACT FROM AUTHOR]

Integrated radiation‐type metasurfaces (RA‐M) have gained importance in the development of next‐generation wireless communications and integrated electronics. They facilitate advanced electromagnetic (EM) wave control with a single radiation aperture. However, most RA‐Ms fail to simultaneously decouple the amplitude, phase, and polarization information of the spatial radiation wavefront owing to the intrinsic restrictions of the meta‐radiator and limited design strategy. This study proposes and demonstrates a full‐space non‐interleaved RA‐M platform capable of precise complex‐vector‐field (CVF) Jones vector reconstruction of both near and far fields in the microwave region. The method is based on the global interaction of linear‐polarized (LP) meta‐radiators, which are organized via the LP‐basis inverse design methodology; thus, the near‐ and far‐field Jones vectors of the radiated wavefront can be subjected to customized reconstruction. The existing unidirectional meta‐radiators are further pushed to bidirectional spaces, facilitating diverse full‐space multiplexing integrated meta‐devices, such as bidirectional multi‐polarization routers and full‐space vectorial hologram modulators. The proposed RA‐M unlocks the unequaled potential of radiated CVF, thereby paving a promising pathway for integrated electronic device technologies. [ABSTRACT FROM AUTHOR]

Information storage and security are the building blocks of the information age. Optical information storage is a low‐cost, robust, and high‐capacity storage technique. Discovering new optical information storage media and techniques with beyond binary capacity and enhanced security is in demand. Here a beyond‐binary, "burn after read" and rewritable multiplexing optical information storage and encryption method is demonstrated via Ce:YAG trapping states. It is found that the thermo‐luminescence (TL) intensity of Ce:YAG trapping states is writing light power dependent, enabling multi‐gray‐level information storage and encoding.A new strategy to encode multiplexing information in a single pixel, increasing the storage capability is presented. Meanwhile, the burn after read feature protects the data from secondary leakage. This method has wide applications in data storage, anti‐counterfeiting, and encryption. [ABSTRACT FROM AUTHOR]

We describe the details of a digital holographic microscopy diagnostic capable of quantifying both the topography and velocity of a km/s object with adjustable temporal sensitivity. This technique involves spatially multiplexing a double pulse reflected from a target with reference beams of precisely known temporal separation. [ABSTRACT FROM AUTHOR]

The orthogonal frequency-division multiplexing (OFDM) mode with a linear frequency modulation (LFM) signal as the baseband waveform has been widely studied and applied in multiple-input multiple-output (MIMO) radar systems. However, its high sidelobe levels after pulse compression affect the target detection of radar systems. For this paper, theoretical analysis was performed, to investigate the causes of high sidelobe levels in OFDM-LFM waveforms, and a novel waveform optimization design method based on deep neural networks is proposed. This method utilizes the classic ResNeXt network to construct dual-channel neural networks, and a new loss function is employed to design the phase and bandwidth of the OFDM-LFM waveforms. Meanwhile, the optimization factor is exploited, to address the optimization problem of the peak sidelobe levels (PSLs) and integral sidelobe levels (ISLs). Our numerical results verified the correctness of the theoretical analysis and the effectiveness of the proposed method. The designed OFDM-LFM waveforms exhibited outstanding performance in pulse compression and improved the detection performance of the radar. [ABSTRACT FROM AUTHOR]

We propose a differential phase contrast microscopy that enables single‐shot phase imaging for unstained biological samples. The proposed approach employs a ring‐shaped LED array for polarisation multiplexing illumination and a polarisation camera for image acquisition. As such, multiple images of different polarisation angles can be simultaneously captured with a single shot. Through polarisation demultiplexing, the sample phase can therefore be recovered from the single‐shot measurement. Both simulations and experiments demonstrate the effectiveness of the approach. We also demonstrate that ring‐shaped illumination enables higher contrast and lower‐distortion imaging results than disk‐shaped illumination does. The proposed single‐shot approach potentially enables phase contrast imaging for live cell samples in vitro. Lay Description: We propose a microscopy that enables imaging of transparent samples, unstained cells, etc. We demonstrate that the proposed method enables higher contrast and lower‐distortion imaging results than conventional methods, and significantly improves imaging efficiency. The proposed method potentially enables dynamic imaging for live cell samples in vitro. [ABSTRACT FROM AUTHOR]

Quantum network coding (QNC) aims at alleviating quantum communication congestion in quantum networks. Although several QNC protocols have been presented, they cannot meet the practical requirements that part of source nodes intend to transmit their quantum states with same or different qubit numbers via the bottleneck network simultaneously. Here, the study presents a flexible QNC protocol by using quantum multiplexing. First, the entangled pairs are generated between adjacent nodes in a heralded way by using quantum multiplexing. Then the quantum memories of the source nodes and the ones of the corresponding target nodes are entangled when the intermediate nodes execute multiple rounds of entanglement swapping operations on their quantum memories. Finally, the quantum states are transmitted from the source nodes to their corresponding target nodes by means of quantum teleportation. Compared with the existing protocols, the protocol allows an arbitrary part of the source nodes to transmit their quantum states with same or different qubit numbers via the bottleneck network simultaneously, thereby exhibiting its flexibility. [ABSTRACT FROM AUTHOR]

Multimode silicon photonics, leveraging mode-division multiplexing technologies, offers significant potential to increase capacity of large-scale multiprocessing systems for on-chip optical interconnects. These technologies have implications not only for telecom and datacom applications, but also for cutting-edge fields such as quantum and nonlinear photonics. Thus, the development of compact, low-loss and low-crosstalk multimode devices, in particular mode exchangers, is crucial for effective on-chip mode manipulation. This work introduces a novel mode exchanger that exploits the properties of subwavelength grating metamaterials and symmetric Y-junctions, achieving low losses and crosstalk over a broad bandwidth and a compact size of only 6.5 µm × 2.6 µm. The integration of SWG nanostructures in our design enables precise control of mode exchange through different propagation constants in the arms and metamaterial, and takes advantage of dispersion engineering to broaden the operating bandwidth. Experimental characterization demonstrates, to the best of our knowledge, the broadest operational bandwidth covering from 1,420 nm to 1,620 nm, with measured losses as low as 0.5 dB and extinction ratios higher than 10 dB. Enhanced performance is achieved within a 149 nm bandwidth (1,471–1,620 nm), showing measured losses below 0.4 dB and extinction ratios greater than 18 dB. [ABSTRACT FROM AUTHOR]

An extremely large-scale antenna array (ELAA) can potentially provide significantly increased spatial multiplexing and beamforming gains, as well as enhanced localization capability. While presenting new potential, its near-field propagation and spatial non-stationary properties also impose a great challenge on the receiver design. This paper focuses on the receiver design in an uplink orthogonal frequency-division multiplexing system with a planar ELAA deployed at the base station. To solve the challenging problem of 3D user localization and channel estimation with the planar ELAA, a space-frequency user localization and channel reconstruction (SF-ULCR) receiver is proposed. Under the Bayesian framework, an extended probability model is first established, to capture the channel structural information comprehensively, based on which an iterative receiver consisting of three modules is derived: element-wise line spectrum estimation (ELSE), distance parameter estimation (DPE), and near-field localization (NFL). In particular, the ELSE module handles the line spectrum relationships among multiple subcarriers in the frequency domain, the DPE module extracts and integrates the distance information from the line spectrum parameters, and the NFL module utilizes the messages of distances for user localization based on near-field spatial characteristics. Our numerical results demonstrate that the proposed SF-ULCR algorithm outperforms existing baselines in terms of channel estimation and localization performance, and that it approaches the Cramèr–Rao bound. [ABSTRACT FROM AUTHOR]

This paper proposes a multiplexing multi-scale features network (MMF-Network) for salient target detection to tackle the issue of incomplete detection structures when identifying salient targets across different scales. The network, based on encoder–decoder architecture, integrates a multi-scale aggregation module and a multi-scale visual interaction module. Initially, a multi-scale aggregation module is constructed, which, despite potentially introducing a small amount of noise, significantly enhances the high-level semantic and geometric information of features. Subsequently, SimAM is employed to emphasize feature information, thereby highlighting the significant target. A multi-scale visual interaction module is designed to enable compatibility between low-resolution and high-resolution feature maps, with dilated convolutions utilized to expand the receptive field of high-resolution feature maps. Finally, the proposed MMF-Network is tested on three datasets: DUTS-Te, HUK-IS, and PSCAL-S, achieving scores of 0.887, 0.811, and 0.031 in terms of its F-value SSIM and MA, respectively. The experimental results demonstrate that the MMF-Network exhibits a superior performance in salient target detection. [ABSTRACT FROM AUTHOR]

This study re-introduces a protein-free rapid test method for nucleic acids on paper based lateral flow assays utilizing special multichannel nitrocellulose membranes and DNA-Gold conjugates, achieving significantly enhanced sensitivity, easier protocols, reduced time of detection, reduced costs of production and advanced multiplexing possibilities. A protein-free nucleic acid-based lateral flow assay (NALFA) with a limit of detection of 1 pmol of DNA is shown for the first time. The total production duration of such an assay was successfully reduced from the currently known several days to just a few hours. The simplification and acceleration of the protocol make the method more accessible and practical for various applications. The developed method supports multiplexing, enabling the simultaneous detection of up to six DNA targets. This multiplexing capability is a significant improvement over traditional line tests and offers more comprehensive diagnostic potential in a single assay. The approach significantly reduces the run time compared to traditional line tests, which enhances the efficiency of diagnostic procedures. The protein-free aspect of this assay minimizes the prevalent complications of cross-reactivity in immunoassays especially in cases of multiplexing. It is also demonstrated that the NALFA developed in this study is amplification-free and hence does not rely on specialized technicians, nor does it involve labour-intensive steps like DNA extraction and PCR processes. Overall, this study presents a robust, efficient, and highly sensitive platform for DNA or RNA detection, addressing several limitations of current methods documented in the literature. The advancements in sensitivity, cost reduction, production time, and multiplexing capabilities mark a substantial improvement, holding great potential for various applications in diagnostics, forensics, and molecular biology. [ABSTRACT FROM AUTHOR]

Purpose: To compare the performance of multi‐echo (ME) and time‐division multiplexing (TDM) sequences for accelerated relaxation‐diffusion MRI (rdMRI) acquisition and to examine their reliability in estimating accurate rdMRI microstructure measures. Method: The ME, TDM, and the reference single‐echo (SE) sequences with six TEs were implemented using Pulseq with single‐band (SB) and multi‐band 2 (MB2) acceleration factors. On a diffusion phantom, the image intensities of the three sequences were compared, and the differences were quantified using the normalized RMS error (NRMSE). Shinnar–Le Roux (SLR) pulses were implemented for the SB‐ME and SB‐SE sequences to investigate the impact of slice profiles on ME sequences. For the in‐vivo brain scan, besides the image intensity comparison and T2‐estimates, different methods were used to assess sequence‐related effects on microstructure estimation, including the relaxation diffusion imaging moment (REDIM) and the maximum‐entropy relaxation diffusion distribution (MaxEnt‐RDD). Results: TDM performance was similar to the gold standard SE acquisition, whereas ME showed greater biases (3–4× larger NRMSEs for phantom, 2× for in‐vivo). T2 values obtained from TDM closely matched SE, whereas ME sequences underestimated the T2 relaxation time. TDM provided similar diffusion and relaxation parameters as SE using REDIM, whereas SB‐ME exhibited a 60% larger bias in the map and on average 3.5× larger bias in the covariance between relaxation‐diffusion coefficients. Conclusion: Our analysis demonstrates that TDM provides a more accurate estimation of relaxation‐diffusion measurements while accelerating the acquisitions by a factor of 2 to 3. [ABSTRACT FROM AUTHOR]

Abstract The study of rapid and stochastic events that involve multiple species, such as chemical reactions and plasma dynamics, requires means to capture multispectral information in two dimensions at both high temporal- and spatial resolution. Commercially available cameras that provide high temporal resolution are based on either signal intensification or rapid data acquisition. Intensified cameras provide extremely short acquisition times using intensification by means of micro channel plates, but the conversion between electrons and photons makes these cameras inherently monochrome. In contrast, high-speed cameras can achieve color-sensitivity through integrated Bayer filters but suffer from a reduced light collection efficiency and a fixed spectral composition. In this article we present a non-integrated optical arrangement for instantaneous multispectral imaging based on FRAME image multiplexing. By spectrally separating the signal using lossless dichroic mirrors, a 16-fold increase in light-collection efficiency is gained (compared to past solutions), resulting in an equivalent increase in temporal resolution. This improvement provides new avenues for multispectral imaging of rapid events. We demonstrate the system’s versatility and suitability for studies of such processes by applying it for (i) temperature mapping using a high-resolution CCD camera, (ii) high-speed videography up to 10 kHz at four spectral channels and (iii) dual-species visualization in a plasma discharge using an intensified sCMOS camera.

Janus metasurfaces, offering versatile light manipulation contingent on incident direction, are explored across microwave to mid‐infrared spectra. Nonetheless, prior designs often resort to spatial multiplexing or vertical stacking, entailing complex fabrication. Metallic Janus metasurfaces, owing to material properties, suffer notable Ohmic losses in the visible spectrum. In this study, Single‐layer TiO2‐based Janus metasurfaces with arbitrary polarization control is experimentally demonstrated, exhibiting directionally asymmetric functionalities in spin and orbital angular momentum (OAM). A novel Jones matrix formulation tailored for Janus metasurfaces is presented, enabling efficient generation of two asymmetric, high‐purity OAM states of vortex beams at wavelength of 532 nm, contingent on incidence direction. This innovation facilitates compact and versatile phase manipulation, encompassing applications such as lasers and optical combiners, thereby expanding its utility across diverse domains. [ABSTRACT FROM AUTHOR]

Fluorescence lifetime imaging microscopy (FLIM) opens new dimensions for highly multiplexed imaging in live cells and organisms using differences in fluorescence lifetime to distinguish spectrally identical fluorescent probes. Here, a set of fluorescence‐activating and absorption‐shifting tags (FASTs) capable of modulating the fluorescence lifetime of embedded fluorogenic 4‐hydroxybenzylidene rhodanine (HBR) derivatives is described. It is shown that changes in the FAST protein sequence can vary the local environment of the chromophore and lead to significant changes in fluorescence lifetime. These fluorescence lifetime‐modulating tags enable multiplexed imaging of up to three targets in one spectral channel using a single HBR derivative in live cells and live zebrafish larvae. The combination of fluorescence lifetime multiplexing with spectral multiplexing allows to successfully image six targets in live cells, opening great prospects for multicolor fluorescence lifetime multiplexing. [ABSTRACT FROM AUTHOR]

Immunohistochemistry is a crucial method for detecting specific proteins within tissue samples, yet constrained to one biomarker per tissue section. Multiplexed immunofluorescence, while allowing simultaneous visualization of multiple proteins, faces limitations in the number of simultaneous fluorescent labels due to spectral overlap. Although cyclic immunofluorescence techniques have successfully broadened antibody staining capacities in a single tissue sample, they are plagued by time-consuming and labor-intensive procedures, sample degradation risks, and inability to scale beyond thin sections. In this study, we introduce the use of 3D confocal Fluorescence Lifetime Imaging Microscopy as a high-throughput, multiplexed immunofluorescence platform that can differentiate 11 or more biomarkers in 3D tissue volumes. Leveraging both spectral and lifetime information, this approach allows for practical spatial biology in thin sections that can readily scale to larger volumes of tissue. We believe that this highly multiplexed and versatile biomarker imaging platform will significantly expedite cancer research and enable new translational approaches in the future. Confocal Fluorescence Lifetime Imaging Microscopy is introduced for highly multiplexed immunofluorescence, enabling the differentiation of 11+ biomarkers in 3D tissue, a technique with potential for interpreting the spatial heterogeneity of thick tumor samples. [ABSTRACT FROM AUTHOR]

Holography is an ideal solution for truly 3D display. Complex‐amplitude hologram can realize high quality reconstructions compared to amplitude‐only hologram and phase‐only hologram. It is difficult for conventional spatial light modulators to achieve complex‐amplitude holographic display while ensuring temporal and spatial resolution, let alone color complex‐amplitude holographic display. Benefiting from the subwavelength pixel size and the powerful multi‐dimensional electromagnetic wave control capabilities, a few metasurface hologram with large viewing angle, high resolution, and no high‐order diffraction crosstalk based on complex‐amplitude control have been studied and realized. Nevertheless, colorful complex‐amplitude metasurface holography at visible frequency has not been implemented yet. Here a complex‐amplitude dual‐wavelength metasurface holography is proposed by using a single cross‐shaped meta‐atom. The polarization conversion efficiency of each wavelength channel is controlled by adjusting the geometric size, while the phase value from 0 to 2π is manipulated based on the Pancharatnam–Berry(PB) phase by rotating the meta‐atom. Without spatial multiplexing, the high‐resolution property of the metasurface is retained. The designed metasurface achieves dual‐color holographic display in the far‐field and the experimental results agree well with the simulation results. The proposed metasurface opens a pathway for high quality color holographic displays and other applications that require complex‐amplitude modulation at different wavelengths. [ABSTRACT FROM AUTHOR]

Artificial neuromorphic devices can emulate dendric integration, axonal parallel transmission, along with superior energy efficiency in facilitating efficient information processing, offering enormous potential for wearable electronics. However, integrating such circuits into textiles to achieve biomimetic information perception, processing, and control motion feedback remains a formidable challenge. Here, we engineer a quasi-solid-state iontronic synapse fiber (ISF) comprising photoresponsive TiO2, ion storage Co-MoS2, and an ion transport layer. The resulting ISF achieves inherent short-term synaptic plasticity, femtojoule-range energy consumption, and the ability to transduce chemical/optical signals. Multiple ISFs are interwoven into a synthetic neural fabric, allowing the simultaneous propagation of distinct optical signals for transmitting parallel information. Importantly, IFSs with multiple input electrodes exhibit spatiotemporal information integration. As a proof of concept, a textile-based multiplexing neuromorphic sensorimotor system is constructed to connect synaptic fibers with artificial fiber muscles, enabling preneuronal sensing information integration, parallel transmission, and postneuronal information output to control the coordinated motor of fiber muscles. The proposed fiber system holds enormous promise in wearable electronics, soft robotics, and biomedical engineering. [ABSTRACT FROM AUTHOR]

A green communication scheme using an orthogonal wavefront (WF) multiplexing (Muxing) scheme spatially combined with orthogonal frequency‐division multiplexing (OFDM) techniques is proposed. It forms a spatial WF OFDM transceiver. The WF Muxing technique serves as the preprocessing and postprocessing method of the WF OFDM transceiver. With coordinated multiple point forward transmission, this spatial WF OFDM system establishes a communication network. It can be applied to multiple base stations (BSs) with down links to single or multiple mobile units (MUs). Although signals are received non‐coherently due to different distances between BSs and MUs, they can be compensated and coherently combined via adaptive equalizers at MUs. This is achieved by using pilot signals with an optimization method at the receiver of MUs. Simulation results demonstrate that the WF OFDM scheme obtains the same bit error rate (BER) as predicted by theory in an additive white Gaussian noise (AWGN) channel. Moreover, the required effective equivalent isotropically radiated power (EIRP) from BSs to the MUs is significantly reduced due to multiple non‐coherent transmission. Accordingly, the interference to adjacent frequency bands’ signals will be low. This green communication network is achieved via the combination of WF Muxing, OFDM, and optimization at the receiver together. More investigations are needed to show that this WF OFDM transceiver can be applied to frequency selective mobile fading channels. [ABSTRACT FROM AUTHOR]