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1. Autophagy

2. Modulators of 14-3-3 protein-protein interactions

3. A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

4. Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

5. GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

6. Molecular Mechanisms of Stem Cell Pluripotency and Cell Fate Specification

7. Synthesis, Pim kinase inhibitory potencies and in vitro antiproliferative activities of diversely substituted pyrrolo[2,3-a]carbazoles

8. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

9. Proteomic and functional comparison between human induced and embryonic stem cells.

10. Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons.

11. The R1441C-Lrrk2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner in mice.

12. Opposing roles for AMPK in regulating distinct mitophagy pathways.

13. Unraveling the Bivalent and Rapid Interactions Between a Multivalent RNA Recognition Motif and RNA: A Kinetic Approach.

14. Suppression of non-muscle myosin II boosts T cell cytotoxicity against tumors.

16. Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial.

18. Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response.

19. Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer.

20. Artificial targeting of autophagy components to mitochondria reveals both conventional and unconventional mitophagy pathways.

21. PROTAC-mediated conditional degradation of the WRN helicase as a potential strategy for selective killing of cancer cells with microsatellite instability.

22. Enhanced Effects of Intermittent Fasting by Magnetic Fields in Severe Diabetes.

23. An acidic loop in the forkhead-associated domain of the yeast meiosis-specific kinase Mek1 interacts with a specific motif in a subset of Mek1 substrates.

24. Additional feedforward mechanism of Parkin activation via binding of phospho-UBL and RING0 in trans .

25. PIEZO1 mechanically regulates the antitumour cytotoxicity of T lymphocytes.

26. CMG helicase disassembly is essential and driven by two pathways in budding yeast.

27. Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue.

28. Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection.

29. Chemo-Phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response Regulators.

30. Reframing the clinical phenotype and management of cryptococcal meningitis.

31. VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.

32. Targeted dephosphorylation of SMAD3 as an approach to impede TGF-β signaling.

34. DEGRONOPEDIA: a web server for proteome-wide inspection of degrons.

35. Targeted dephosphorylation of TFEB promotes its nuclear translocation.

36. PSMF1 variants cause a phenotypic spectrum from early-onset Parkinson's disease to perinatal lethality by disrupting mitochondrial pathways.

37. Mechanism of human PINK1 activation at the TOM complex in a reconstituted system.

38. RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses.

39. An acidic loop in the FHA domain of the yeast meiosis-specific kinase Mek1 interacts with a specific motif in a subset of Mek1 substrates.

40. Deletion of CD44 promotes adipogenesis by regulating PPARγ and cell cycle-related pathways.

41. Next questions in autophagy.

42. Retromer-dependent lysosomal stress in Parkinson's disease.

43. PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons.

44. Discovery and characterization of noncanonical E2-conjugating enzymes.

45. PINK1 regulated mitophagy is evident in skeletal muscles.

46. Art, Intuition, and Identity in Ramón y Cajal.

47. The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.

48. UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.

49. Targeted protein degradation via intramolecular bivalent glues.

50. The histone chaperone SPT2 regulates chromatin structure and function in Metazoa.

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