1. International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation
- Author
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Tereza Martinu, Angela Koutsokera, Christian Benden, Edward Cantu, Daniel Chambers, Marcelo Cypel, Jeffrey Edelman, Amir Emtiazjoo, Andrew J. Fisher, John R. Greenland, Don Hayes, David Hwang, Brian C. Keller, Erika D. Lease, Michael Perch, Masaaki Sato, Jamie L. Todd, Stijn Verleden, Jan von der Thüsen, S. Samuel Weigt, Shaf Keshavjee, Cecilia Chaparro, David Wilson Roe, Frank D'Ovidio, George Chaux, Greg Snell, Laurent Godinas, Mohamed Al-Aloul, Steven Hays, Jamie Todd, Amy Rigby, Louis Clauden, Matthew Morrell, Puneet Garcha, Sanjeev Raman, Soma Jyothula, Michael Trotter, Erika Lease, Cassie Kennedy, Chadi A Hage, Saima Aslam, Shahid Husain, Katharina Wassilew, Reinaldo Rampolla-Selles, Siddhartha G Kapnadak, Umesh Goswami, John Greenland, Aric Gregson, Bart Vanaudenaerde, Tji Gan, Brian Keller, Laura K Frye, Margaret Hannan, Harish Seethamraju, Rade Tomic, Remzi Bag, Alicia Mitchell, Jorge Mallea, Maria Crespo, Sangeeta Bhorade, Cantu Edward, Cypel Marcelo, Gundeep Dhillon, Jason Christie, Jessica GY Luc, Keith M Wille, Olufemi Akindipe, Omar Mohamedaly, Christopher Wigfield, Ernestina Melicoff-Portillo, Marc Schecter, Shailendra Das, Ani Orchanian-Cheff, George Tomlinson, Pathology, bronchoalveolar lavage standardization workgroup, Martinu, T., Koutsokera, A., Keshavjee, S., Weigt, S.S., Sato, M., Chaparro, C., Roe, D.W., D'Ovidio, F., Chaux, G., Snell, G., Godinas, L., Al-Aloul, M., Hays, S., Todd, J., Perch, M., Rigby, A., Clauden, L., Morrell, M., Garcha, P., Raman, S., Jyothula, S., Trotter, M., Lease, E., Edelman, J., Kennedy, C., Hage, C.A., Aslam, S., Husain, S., von der Thüsen, J., Fisher, A.J., Wassilew, K., Rampolla-Selles, R., Kapnadak, S.G., Goswami, U., Greenland, J., Emtiazjoo, A., Gregson, A., Vanaudenaerde, B., Gan, T., Hwang, D., Keller, B., Frye, L.K., Hannan, M., Seethamraju, H., Tomic, R., Bag, R., Mitchell, A., Verleden, S., Chambers, D., Mallea, J., Crespo, M., Bhorade, S., Edward, C., Marcelo, C., Dhillon, G., Christie, J., Luc, J.G., Wille, K.M., Akindipe, O., Mohamedaly, O., Wigfield, C., Hayes, D., Benden, C., Melicoff-Portillo, E., Schecter, M., Das, S., Orchanian-Cheff, A., Tomlinson, G., and Bronchoalveolar Lavage Standardiza
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RCF, relative centrifugal force ,Standardization ,medicine.medical_treatment ,Sample processing ,IDSA, Infectious Disease Society of America ,Cardiorespiratory Medicine and Haematology ,ATS, American Thoracic Society ,030230 surgery ,Bronchoalveolar Lavage ,PCR, polymerase chain reaction ,0302 clinical medicine ,Bronchoscopy ,bronchoalveolar lavage standardization workgroup ,Medicine ,bronchoalveolar lavage ,Lung ,EVLP, ex-vivo lung perfusion ,Sample handling ,medicine.diagnostic_test ,VZV, varicella zoster virus (VZV) ,methodology ,LTx, lung transplantation ,respiratory system ,ERS, European Respiratory Society ,Bronchoalveolar Lavage/standards ,Consensus ,Heart Transplantation/standards ,Humans ,Lung Transplantation/standards ,bronchial wash ,donor bronchoscopy ,lung transplantation ,pediatric bronchoscopy ,standardization ,BAL, bronchoalveolar lavage ,Cardiology and Cardiovascular Medicine ,Lung Transplantation ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,AMR, antibody-mediated rejection ,CLAD, chronic lung allograft dysfunction ,Article ,RPM, revolutions per minute ,03 medical and health sciences ,Clinical Research ,Abbreviations: AFB, acid-fast bacilli ,Lung transplantation ,AR, acute rejection ,PJP, Pneumocystis jiroveci pneumonia ,Intensive care medicine ,CF, cystic fibrosis ,Transplantation ,business.industry ,Organ Transplantation ,CMV, cytomegalovirus ,respiratory tract diseases ,ISHLT, International Society for Heart and Lung Transplantation ,Bronchoalveolar lavage ,030228 respiratory system ,ML, middle lobe ,HSV, herpes simplex virus ,Heart Transplantation ,ASM, American Society for Microbiology ,Surgery ,Human medicine ,RSV, respiratory syncytial virus ,business ,BW, bronchial wash - Abstract
Bronchoalveolar lavage (BAL) is a key clinical and research tool in lung transplantation (LTx). However, BAL collection and processing are not standardized across LTx centers. This International Society for Heart and Lung Transplantation-supported consensus document on BAL standardization aims to clarify definitions and propose common approaches to improve clinical and research practice standards. The following 9 areas are covered: (1) bronchoscopy procedure and BAL collection, (2) sample handling, (3) sample processing for microbiology, (4) cytology, (5) research, (6) microbiome, (7) sample inventory/tracking, (8) donor bronchoscopy, and (9) pediatric considerations. This consensus document aims to harmonize clinical and research practices for BAL collection and processing in LTx. The overarching goal is to enhance standardization and multicenter collaboration within the international LTx community and enable improvement and development of new BAL-based diagnostics. ispartof: JOURNAL OF HEART AND LUNG TRANSPLANTATION vol:39 issue:11 pages:1171-1190 ispartof: location:United States status: published
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- 2020