29 results on '"MING-YUAN REN"'
Search Results
2. Damping analysis of micro-gyroscope with ball-disk rotor
- Author
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Sheng-Le Ren and Ming-Yuan Ren
- Subjects
Physics ,QC1-999 - Abstract
According to the structure of the micro-gyroscope with a ball-disk rotor, the corresponding Reynolds equation is solved by using the motion equation, continuity equation, and state equation. The damping coefficients of axial vibration, radial vibration, and rotation around the Z axis are derived theoretically. The damping theoretical model of the micro-gyroscope is constructed to analyze the gas film damping and oil film damping of the ball-disk rotor in three degrees of freedom motion.
- Published
- 2022
- Full Text
- View/download PDF
3. The influence of nonideal factors on the capacitance permittivity in a liquid-suspended rotor micro-gyroscope
- Author
-
Ming-Yuan Ren, Hai-Feng Zhang, Xiao-Wei Liu, and Zhi-Gang Mao
- Subjects
Physics ,QC1-999 - Abstract
The nonideal factors of a liquid-suspended rotor micro-gyroscope include the gas-liquid two-phase flow voids, medium temperature and its dielectric relaxation, in which the role of the nonideal factors on the capacitor dielectric constant is altered, thereby affecting the capacitance detection precision of the micro-gyroscope. By comparing four different liquid media, the experimental results reveal the nonideal character of the capacitor dielectric constant. The 7# white oil is suitable for use as the liquid-suspended gyro cavity liquid medium.
- Published
- 2014
- Full Text
- View/download PDF
4. High resolution capacitance detection circuit for rotor micro-gyroscope
- Author
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Ming-Yuan Ren, Hai-Feng Zhang, Xiao-Wei Liu, and Zhi-Gang Mao
- Subjects
Physics ,QC1-999 - Abstract
Conventional methods for rotor position detection of micro-gyroscopes include common exciting electrodes (single frequency) and common sensing electrodes (frequency multiplex), but they have encountered some problems. So we present a high resolution and low noise pick-off circuit for micro-gyroscopes which utilizes the time multiplex method. The detecting circuit adopts a continuous-time current sensing circuit for capacitance measurement, and its noise analysis of the charge amplifier is introduced. The equivalent output noise power spectral density of phase-sensitive demodulation is 120 nV/Hz1/2. Tests revealed that the whole circuitry has a relative capacitance resolution of 1 × 10−8.
- Published
- 2014
- Full Text
- View/download PDF
5. CMOS readout circuit for piezo-resistive accelerometer.
- Author
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Ming-Yuan Ren and Chun-Xiang Zhang
- Published
- 2012
- Full Text
- View/download PDF
6. A New Mechanism of Naming Topological Entities for Semantic Feature Operations.
- Author
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Xue-Yao Gao, Chun-Xiang Zhang, Ming-Yuan Ren, Shang-Min Gao, and Yong Liu
- Published
- 2012
- Full Text
- View/download PDF
7. Multiple Linear Regression for Extracting Phrase Translation Pairs.
- Author
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Chun-Xiang Zhang, Ming-Yuan Ren, Zhimao Lu, Ying-Hong Liang, Da-Song Sun, and Yong Liu
- Published
- 2011
- Full Text
- View/download PDF
8. Measuring optical vortices in a speckle pattern by means of dual shearing-type Sagnac interferometers
- Author
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Han-Tao Wang, Hua-Jun Zhang, Ming-Yuan Ren, Wen-Kai Yao, and Yu Zhang
- Subjects
Electrical and Electronic Engineering ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials - Published
- 2022
- Full Text
- View/download PDF
9. Oceanic non-Kolmogorov optical turbulence and spherical wave propagation
- Author
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Ming Yuan Ren, Han Tao Wang, Jian Dong Cai, Jin Ren Yao, Yu Zhang, Huajun Zhang, and Olga Korotkova
- Subjects
Wave propagation ,Scalar (mathematics) ,Temperature salinity diagrams ,FOS: Physical sciences ,02 engineering and technology ,01 natural sciences ,Power law ,010309 optics ,Physics::Fluid Dynamics ,Optics ,0103 physical sciences ,Statistical physics ,Physics ,Mutual coherence ,Turbulence ,business.industry ,Spectral density ,021001 nanoscience & nanotechnology ,Atomic and Molecular Physics, and Optics ,Nonlinear Sciences::Chaotic Dynamics ,Physics - Atmospheric and Oceanic Physics ,Atmospheric and Oceanic Physics (physics.ao-ph) ,0210 nano-technology ,business ,Coherence (physics) ,Optics (physics.optics) ,Physics - Optics - Abstract
Light propagation in turbulent media is conventionally studied with the help of the spatio-temporal power spectra of the refractive index fluctuations. In particular, for natural water turbulence several models for the spatial power spectra have been developed based on the classic, Kolmogorov postulates. However, as currently widely accepted, non-Kolmogorov turbulent regime is also common in the stratified flow fields, as suggested by recent developments in atmospheric optics. Until now all the models developed for the non-Kolmogorov optical turbulence were pertinent to atmospheric research and, hence, involved only one advected scalar, e.g., temperature. We generalize the oceanic spatial power spectrum, based on two advected scalars, temperature and salinity concentration, to the non-Kolmogorov turbulence regime, with the help of the so-called "Upper-Bound Limitation" and by adopting the concept of spectral correlation of two advected scalars. The proposed power spectrum can handle general non-Kolmogorov, anisotropic turbulence but reduces to Kolmogorov, isotropic case if the power law exponents of temperature and salinity are set to 11/3 and anisotropy coefficient is set to unity. To show the application of the new spectrum, we derive the expression for the second-order mutual coherence function of a spherical wave and examine its coherence radius (in both scalar and vector forms) to characterize the turbulent disturbance. Our numerical calculations show that the statistics of the spherical wave vary substantially with temperature and salinity non-Kolmogorov power law exponents and temperature-salinity spectral correlation coefficient. The introduced spectrum is envisioned to become of significance for theoretical analysis and experimental measurements of non-classic natural water double-diffusion turbulent regimes.
- Published
- 2021
10. Zerumbone inhibits melanoma cell proliferation and migration by altering mitochondrial functions
- Author
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Ming‑Yuan Ren, Si Li, Shi‑Jun Feng, Guoqiang Zhang, Yi Cheng, Shun‑Qiang Gao, Hua Yan, Zheng‑Xiang Wang, and Cai‑Xia Hu
- Subjects
0301 basic medicine ,Cancer Research ,Oncogene ,cell migration ,Cell growth ,Cell ,Cell migration ,Articles ,Cell cycle ,TFAM ,Biology ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,cell proliferation ,Oncology ,mitochondrial function ,Cell culture ,Apoptosis ,030220 oncology & carcinogenesis ,medicine ,Cancer research ,melanoma ,zerumbone - Abstract
It has been reported that zerumbone (ZER) has marked effects on the regulation of cell proliferation and migration in multiple types of cancer, and has anti-cancer effects on various types of malignant cell. However, the effects and underlying molecular mechanisms of treatment with ZER on melanoma cells remain unclear. In the present study, the effect of treatment with ZER on the proliferation, migration and mitochondrial function of the human melanoma cell line CHL-1 was investigated. The results of the present study indicated that treatment with ZER significantly inhibited CHL-1 cell proliferation (P
- Published
- 2017
11. A 4th-Order Wideband Sigma Delta Modulator Using Linear System Theory Technique
- Author
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Yong-sheng Zhang, Ming-yuan Ren, Wei-kun Wu, Zhen-xi Bao, Chao Li, Hong-guo Zhang, and Zi-wei Zhao
- Subjects
Coupling ,Engineering ,business.industry ,Noise (signal processing) ,020208 electrical & electronic engineering ,Linear system ,020206 networking & telecommunications ,02 engineering and technology ,Delta-sigma modulation ,Transfer function ,Signal ,Sampling (signal processing) ,Control theory ,Signal Processing ,0202 electrical engineering, electronic engineering, information engineering ,Electronic engineering ,Wideband ,business - Abstract
A 4th-Order Wideband Sigma Delta modulator structure is proposed in this paper, which uses linear system theory technique. There are many implementation techniques to improve the performance of Sigma Delta ADCs, such as noise coupling, differential sampling and dynamic elements matching. An extra loop delay is needed to be added in the system. This paper explains how to make the modulator stable with the addition of feed-forward and feed-back branches which are used to compensate the extra loop delay. Next, we restore the signal and noise transfer functions. A 4th-Order Wideband deltasigma modulator have been designed and simulated to verify the method.
- Published
- 2016
- Full Text
- View/download PDF
12. A 4th-Order Low-distortion Low-pass Modulator Using Timing-Sharing Technique
- Author
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Ming-yuan Ren, Hong-guo Zhang, and Ji-bao Zhang
- Subjects
Adder ,Effective number of bits ,Computer science ,Quantization (signal processing) ,Integrator ,Low-pass filter ,Signal Processing ,Bandwidth (signal processing) ,Electronic engineering ,Oversampling ,Delta-sigma modulation - Abstract
A 4th-Order low-distortion low-pass ΣΔ modulator structure is proposed in this paper, which uses the timing-sharing between the 3rd and 4th integrators during one clock phase. Compared with conventional cascade of integrators with distributed feed-forward (CIFF) sigma-delta modulator structure, the proposed structure not only solves the critical timing issue for the quantizer and feedback DAC path, but also eliminates an extra active adder to sum up the input feed-forward. By methods of delay redistribution structure, the time for quantization and feedback dynamic element match (DEM) operation can be extended from a non-overlapping interval for a conventional low-distortion structure to half of the sampling clock period. Capacitive input feed-forward (CIF) methodology eliminates the adder in front of the quantizer. Further, the op-amp of the last integrator is used as an active adder by op-amp sharing. Therefore, the power consumption can be reduced and the linearity of the feedback DAC is improved because of the increasing time which used for implementation of DEM algorism. The proposed 4th-Order low-distortion low-pass ΣΔ modulator with 4-bit quantizer is simulated in MATLAB. From the simulation results, the proposed structure can achieve a peak SNR (signal- to-noise ratio) of 87dB with 2.5MHz bandwidth under 32 oversampling ratio at 160MHz sampling frequency and the ENOB of 14.234bits in non-ideal condition.
- Published
- 2015
- Full Text
- View/download PDF
13. High Resolution Micro-Displacement Sensing Circuit for Rotor Micro-Gyroscope
- Author
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Xiao Wei Liu, Haifeng Zhang, Zhi Gang Mao, and Ming Yuan Ren
- Subjects
Noise power ,Engineering ,business.industry ,Rotor (electric) ,Mechanical Engineering ,Electrical engineering ,Gyroscope ,Diode-or circuit ,Hardware_PERFORMANCEANDRELIABILITY ,Discrete circuit ,Capacitance ,law.invention ,CMOS ,Parasitic capacitance ,Mechanics of Materials ,law ,Hardware_INTEGRATEDCIRCUITS ,General Materials Science ,business ,Hardware_LOGICDESIGN - Abstract
A novel CMOS interface circuit with high resolution is designed and realized to achieve the integration of interface circuit for liquid suspended rotor micro-gyroscope. The detecting circuit adopts continuous-time current sensing circuit for capacitance measurement. The equivalent output noise power spectral density of phase-sensitive demodulation is 120 nV/Hz1/2. The whole circuitry is realized with 0.5 μm 2P2M CMOS process and its testing results show the circuit has a relative capacitance resolution of 1×10-8, in which the power supply is 18 V and the power consumption is 30 mW. The area of the chip is merely 18.5 mm2.
- Published
- 2015
- Full Text
- View/download PDF
14. Optimized Technical Characteristics of Polysilicon Nanofilm
- Author
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Lin Hai Cui, Xue Bin Lu, and Ming Yuan Ren
- Subjects
Microelectromechanical systems ,Materials science ,Doping ,General Engineering ,Nanotechnology ,Point (geometry) ,Piezoresistive effect ,Engineering physics - Abstract
In order to take good advantage of polysilicon nanofilm, optimized technical characteristics of the polysilicon nanofilm are very necessary to investigated. In this paper, the polysilicon nanofilms were prepared under different technical parameters, including thickness and doping concentration, which are very important for preparation of the nanofilm. The experimental results of piezoresistive and temperature characteristics show that the optimized technical characteristics are followed, the thickness is about 90nm, and the doping concentration is about 4.1×?1019cm-3 or between 2.0×?1020cm-3 and 4.1×?1020cm-3 from different point of view. The investigations of optimized technical characteristics are very useful for application of the polysilicon nanofilm to piezoresistive sensor.
- Published
- 2014
- Full Text
- View/download PDF
15. A Bandgap Reference with Temperature Coefficient of 13.2 ppm/°C
- Author
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Ming Yuan Ren and En Ming Zhao
- Subjects
Materials science ,Bandgap voltage reference ,business.industry ,Band gap ,General Engineering ,Power (physics) ,CMOS ,Operating temperature ,Electronic engineering ,Optoelectronics ,Silicon bandgap temperature sensor ,business ,Temperature coefficient ,Voltage - Abstract
This paper presents a design and analysis method of a bandgap reference circuit. The Bandgap design is realized through the 0.18um CMOS process. Simulation results show that the bandgap circuit outputs 1.239V in the typical operation condition. The variance rate of output voltage is 0.016mV/°C? with the operating temperature varying from-60°C? to 160°C?. And it is 3.27mV/V with the power supply changes from 1.8V to 3.3V.
- Published
- 2014
- Full Text
- View/download PDF
16. Design of a Fourth-Order Sigma-Delta Modulator for Audio Application
- Author
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Tuo Li, Chang Chun Dong, and Ming Yuan Ren
- Subjects
Computer science ,business.industry ,Bandwidth (signal processing) ,Electrical engineering ,General Medicine ,Delta-sigma modulation ,Fourth order ,CMOS ,Sampling (signal processing) ,Modulation ,Electronic engineering ,business ,Cmos process ,Electronic circuit - Abstract
Based on requirements on high performance and high resolution of modulators, a fourth-order Sigma-Delta modulator for audio application is developed in this paper. The modulator is designed under the commercial 0.5μm CMOS process and the circuits are given simulations by Spectre. The sampling frequency of sigma-delta modulator is 11.264 MHz, and OSR is 256 within the 22 kHz signal bandwidth. Measure performance shows that Sigma-Delta modulator enables its maximum SNR to achieve 103.5dB, and the accuracy of Sigma-Delta modulator is up to 16 bit.
- Published
- 2013
- Full Text
- View/download PDF
17. Design of Pre-Amplifiers for Photoelectric Detector
- Author
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Li Tian, Ming Yuan Ren, Xiao Wei Liu, Zhi Gang Mao, and Wei Wang
- Subjects
Engineering ,Noise temperature ,Current-feedback operational amplifier ,business.industry ,Electrical engineering ,Y-factor ,Hardware_PERFORMANCEANDRELIABILITY ,General Medicine ,Low-noise amplifier ,law.invention ,Hardware_GENERAL ,law ,Hardware_INTEGRATEDCIRCUITS ,Electronic engineering ,Operational amplifier ,Effective input noise temperature ,Instrumentation amplifier ,business ,Direct-coupled amplifier ,Hardware_LOGICDESIGN - Abstract
This paper presents the design of low noise CMOS pre-amplifiers based on photoelectric detection systems, which can directly affect the detecting precision of the whole systems. The design of pre-amplifier circuit from photoelectric detector was introduced. The photoelectric conversion circuit, amplifier circuit bandwidth, amplifier circuit noise, amplifier circuit stabilization and other questions were mainly discussed, and an amplifier circuit capable of effectively decreasing the noise, the temperature drift and a large dynamic range was designed. This paper analyzes the sources of photoelectric detection circuit internal noise, and gives the formulas of internal noise, designs a variable equivalent load photoelectric conversion circuit, and is verified by experiments. Then the result is used to reduce the noise of CMOS based operational amplifiers and finally implement the design work of pre-amp using 0.5μm CMOS Technology.
- Published
- 2013
- Full Text
- View/download PDF
18. Design and Simulation of Photoelectric Detection Circuit for Microfluidics Chip
- Author
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Ming Yuan Ren, Wei Wang, Li Tian, Zhi Gang Mao, and Xiao Wei Liu
- Subjects
Engineering ,business.industry ,Microfluidics ,Electrical engineering ,Hardware_PERFORMANCEANDRELIABILITY ,General Medicine ,Photoelectric effect ,Chip ,Transfer function ,Noise (electronics) ,CMOS ,Filter (video) ,Hardware_INTEGRATEDCIRCUITS ,Electronic engineering ,business ,Sensitivity (electronics) - Abstract
This paper presents a photoelectric detection circuit for microfluidics chip. The proposed photoelectric detection system can reduce noise and increase sensitivity. It is consist of pre-amplifier, ac-amplifier and band-pass filter. The transfer function of photoelectric detection circuit is introduced. The circuit implementations and simulation results are given. The proposed photoelectric detection circuit is suitable for integrated microfluidics chip.
- Published
- 2013
- Full Text
- View/download PDF
19. Micro-Displacement Sensing Circuit for Gyroscope with Levitated Rotor
- Author
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Xiao Wei Liu, Zhi Gang Mao, Ming Yuan Ren, and Wen Zuo
- Subjects
Materials science ,Rotor (electric) ,Mechanical Engineering ,Acoustics ,High resolution ,Gyroscope ,Noise (electronics) ,Displacement (vector) ,law.invention ,Low noise ,Capacitor ,Mechanics of Materials ,law ,Electronic engineering ,General Materials Science - Abstract
This paper presents a micro-displacement sensing circuit, which can detect sensing capacitors of levitated rotor. To ensure the high resolution, noise analysis of pre-amplifier of micro-displacement sensing circuit is conducted. The results show that choosing low noise amp and decreasing Cf /C1 can reduce the electronic noise.
- Published
- 2013
- Full Text
- View/download PDF
20. The Method of Retrieving 3D Parts Based on Cellular Model
- Author
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MingGe Zhai, ShangMing Gao, Xue-Yao Gao, Ming-Yuan Ren, and Chun-Xiang Zhang
- Subjects
Computer Networks and Communications ,Computer science ,Distributed computing ,Cellular model ,Software - Published
- 2012
- Full Text
- View/download PDF
21. Analytical Model of Fluxgate System
- Author
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Xiao Wei Liu, Ming Yuan Ren, Hao Ran Li, and Zhi Gang Mao
- Subjects
Engineering ,Magnetometer ,business.industry ,Mechanical Engineering ,Fluxgate compass ,law.invention ,Amplitude ,Mechanics of Materials ,law ,Driving current ,Harmonic ,Electronic engineering ,General Materials Science ,business - Abstract
This paper presents a complete set of SIMULINK models, which allow exhaustive behavioral simulations of fluxgate system to be performed. The model construction is detailed and it is applied to the Vacquier-type fluxgate sensor. Well known characteristics of these sensors are confirmed through the simulations. In spite of this simplicity, the model has been successfully used to describe the variation of the output of a Vacquier-type fluxgate sensor with the amplitude and the frequency of the driving current. Using a previously developed 2nd harmonic fluxgate magnetometer, some preliminary experimental results are obtained confirming the appearance at its output.
- Published
- 2012
- Full Text
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22. Design of CMOS Instrumentation Amplifier
- Author
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Da-Song Sun, Ming-Yuan Ren, and Chun-Xiang Zhang
- Subjects
Power-added efficiency ,Engineering ,CMFC ,Current-feedback operational amplifier ,business.industry ,RF power amplifier ,Electrical engineering ,General Medicine ,CMOS integrated circuits, Instrumentation amplifier ,law.invention ,law ,Operational transconductance amplifier ,Operational amplifier ,Electronic engineering ,Linear amplifier ,Instrumentation amplifier ,business ,Direct-coupled amplifier ,Engineering(all) - Abstract
A low power CMOS instrumentation amplifier used for biomedical applications is presented in this paper. It consists of a low power operational amplifier with CMFC structure. By analysis and optimization of the parasitic effects and parameters, instrumentation amplifier has better performance in every aspect. This simulation result shows that, in the case of guaranteed bandwidth, the amplifier can suppress flicker noise interference effectively. The instrumentation amplifier designed in 0.5 μm CMOS technology with 3.3 V power supply shows a dynamic range of 70.1 dB and 23.48 ns settling time within 0.05% accuracy. The main amplifier dissipates 10.5mW power. It also includes a bias circuit that dissipates 2.2mW power.
- Published
- 2012
- Full Text
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23. Design and Simulation of Transconductance with Capacitances Feedback Compensation Amplifier
- Author
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Jing Ying Zhao, Hai Guo, Chun Xiang Zhang, and Ming Yuan Ren
- Subjects
Engineering ,FET amplifier ,business.industry ,Transconductance ,Slew rate ,General Medicine ,Fully differential amplifier ,law.invention ,law ,Operational transconductance amplifier ,Electronic engineering ,Operational amplifier ,Multistage amplifier ,business ,Direct-coupled amplifier - Abstract
This paper presents a low-power multistage amplifier with a novel Transconductance with Capacitances Feedback Compensation (TCFC) technique. A transconductance stage and two capacitors introduce negative feedback to a three-stage amplifier, which significantly improves the performance such as gain-bandwidth product, slew rate, stability and sensitivity. Implemented in a commercial 0.5-μm CMOS technology and driving 10pF capacitive load, a three-stage TCFC amplifier achieves over 120dB gain, 1.515MHz GBW and 1.3V/μS average slew rate, while only dissipating 380μW under 3.3V supply.
- Published
- 2011
- Full Text
- View/download PDF
24. Design and Simulation of Low-Power Multistage Amplifiers
- Author
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Ming Yuan Ren
- Subjects
Engineering ,business.industry ,Amplifier ,Capacitive sensing ,General Engineering ,Electrical engineering ,Phase margin ,Frequency compensation ,Slew rate ,Power factor ,Electronic engineering ,Multistage amplifier ,business ,Direct-coupled amplifier - Abstract
This paper presents a low-power multistage amplifier with a novel capacitor-multiplier frequency compensation (CMFC) technique. The proposed compensation strategy can allow the circuit to occupy less silicon area and to drive large capacitive loads more effectively. Moreover, smaller physical capacitance results in higher gain-bandwidth product (GBW) and improved transient responses. Furthermore, the capacitor multiplier stage (CMS) embedded in CMFC creates a left-half plane (LHP) zero, which boosts the phase margin and enhances the stability of the amplifier. Implemented in a commercial 0.5-μm CMOS technology and driving 500pF capacitive load, a three-stage CMFC amplifier achieves over 120dB gain, 1.699MHz GBW and 1.625V/μS average slew rate, while only dissipating 330μW under 3.3V supply.
- Published
- 2011
- Full Text
- View/download PDF
25. Analysis of electromechanical interface model for liquid floated micro-gyroscope
- Author
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Wen Zuo, Ming-Yuan Ren, Xiaowei Liu, and Zhigang Mao
- Subjects
Materials science ,Interface model ,Interface (computing) ,Mechanical engineering ,High resolution ,Gyroscope ,computer.software_genre ,Magnetic liquids ,law.invention ,Simulation software ,Nonlinear system ,Capacitor ,law ,computer - Abstract
This paper presents an electromechancial interface model of liquid floated micro-gyroscope, which can analyze sensing capacitors and resistance of gyroscope. The impacts of them are analyzed and simulated with the simulation software of circuit. The analytic results indicate that the reasonable interface circuit can substantially remove the impacts of these parasitic capacitances, increase the signal noise ratio. To ensure the high resolution, the model of liquid floated micro-gyroscope with ANSOFT conducted. The results show the transfer characteristics of the sensor and nonlinear error of transfer characteristics.
- Published
- 2013
- Full Text
- View/download PDF
26. Extraction of Chinese-English Phrase Translation Pairs
- Author
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Da-Song Sun, Ming-Yuan Ren, Chun-Xiang Zhang, Ying-Hong Liang, Yong Liu, and Zhi-Mao Lu
- Subjects
Parsing ,Phrase ,business.industry ,Computer science ,InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL ,computer.software_genre ,Translation (geometry) ,ComputingMethodologies_ARTIFICIALINTELLIGENCE ,Lexicography ,Tree (data structure) ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Machine translation system ,Artificial intelligence ,business ,computer ,Word (computer architecture) ,Sentence ,Natural language processing - Abstract
Phrase translation pairs are very useful for bilingual lexicography, machine translation system, cross-lingual information retrieval and many applications in natural language processing. In this paper, we align Chinese-English bilingual sentence pairs based on parsing tree of Chinese sentence and word alignment results, which is called as the tree-string alignment. From tree-string alignment, phrase translation pairs are extracted.
- Published
- 2011
- Full Text
- View/download PDF
27. Zerumbone inhibits melanoma cell proliferation and migration by altering mitochondrial functions.
- Author
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HUA YAN, MING-YUAN REN, ZHENG-XIANG WANG, SHI-JUN FENG, SI LI, YI CHENG, CAI-XIA HU, SHUN-QIANG GAO, and GUO-QIANG ZHANG
- Subjects
- *
MELANOMA treatment , *PHYTOCHEMICALS , *CANCER cell proliferation , *CANCER cell migration , *MITOCHONDRIAL physiology , *MITOCHONDRIAL DNA , *TRANSCRIPTION factors - Abstract
It has been reported that zerumbone (ZER) has marked effects on the regulation of cell proliferation and migration in multiple types of cancer, and has anti-cancer effects on various types of malignant cell. However, the effects and underlying molecular mechanisms of treatment with ZER on melanoma cells remain unclear. In the present study, the effect of treatment with ZER on the proliferation, migration and mitochondrial function of the human melanoma cell line CHL-1 was investigated. The results of the present study indicated that treatment with ZER significantly inhibited CHL-1 cell proliferation (P<0.001). Cell migration analysis further demonstrated that ZER inhibited the migration of CHL-1 cells (P<0.001). Treatment with ZER significantly increased cellular reactive oxygen species levels (P<0.001), reduced matrix membrane potential (P<0.001), decreased ATP (P<0.001) and mitochondrial DNA (P<0.001) levels, and decreased mitochondrial transcription factor A mRNA levels (P=0.002). The results of the present study suggested that the inhibition of proliferation and migration was mediated by altered mitochondrial function. In conclusion, the results of the present study suggested that ZER has chemotherapeutic effects on human melanoma cells by altering mitochondrial function. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
28. The influence of nonideal factors on the capacitance permittivity in a liquid-suspended rotor micro-gyroscope
- Author
-
Zhi-Gang Mao, Xiaowei Liu, Haifeng Zhang, and Ming-Yuan Ren
- Subjects
Permittivity ,Materials science ,Rotor (electric) ,General Physics and Astronomy ,Gyroscope ,Dielectric ,Capacitance ,lcsh:QC1-999 ,law.invention ,Capacitor ,law ,Relaxation (physics) ,Capacitance probe ,Composite material ,lcsh:Physics - Abstract
The nonideal factors of a liquid-suspended rotor micro-gyroscope include the gas-liquid two-phase flow voids, medium temperature and its dielectric relaxation, in which the role of the nonideal factors on the capacitor dielectric constant is altered, thereby affecting the capacitance detection precision of the micro-gyroscope. By comparing four different liquid media, the experimental results reveal the nonideal character of the capacitor dielectric constant. The 7# white oil is suitable for use as the liquid-suspended gyro cavity liquid medium.
- Published
- 2014
29. High resolution capacitance detection circuit for rotor micro-gyroscope
- Author
-
Zhi-Gang Mao, Ming-Yuan Ren, Xiaowei Liu, and Haifeng Zhang
- Subjects
Noise power ,Materials science ,Rotor (electric) ,business.industry ,Analytical chemistry ,General Physics and Astronomy ,Gyroscope ,Noise (electronics) ,Capacitance ,lcsh:QC1-999 ,law.invention ,Parasitic capacitance ,law ,Demodulation ,Optoelectronics ,business ,Charge amplifier ,lcsh:Physics - Abstract
Conventional methods for rotor position detection of micro-gyroscopes include common exciting electrodes (single frequency) and common sensing electrodes (frequency multiplex), but they have encountered some problems. So we present a high resolution and low noise pick-off circuit for micro-gyroscopes which utilizes the time multiplex method. The detecting circuit adopts a continuous-time current sensing circuit for capacitance measurement, and its noise analysis of the charge amplifier is introduced. The equivalent output noise power spectral density of phase-sensitive demodulation is 120 nV/Hz1/2. Tests revealed that the whole circuitry has a relative capacitance resolution of 1 × 10−8.
- Published
- 2014
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