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849 results on '"MEZQUITA, LAURA"'

1. CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Author

Skoulidis, Ferdinandos, Araujo, Haniel A., Do, Minh Truong, Qian, Yu, Sun, Xin, Cobo, Ana Galan, Le, John T., Montesion, Meagan, Palmer, Rachael, Jahchan, Nadine, Juan, Joseph M., Min, Chengyin, Yu, Yi, Pan, Xuewen, Arbour, Kathryn C., Vokes, Natalie, Schmidt, Stephanie T., Molkentine, David, Owen, Dwight H., Memmott, Regan, Patil, Pradnya D., Marmarelis, Melina E., Awad, Mark M., Murray, Joseph C., Hellyer, Jessica A., Gainor, Justin F., Dimou, Anastasios, Bestvina, Christine M., Shu, Catherine A., Riess, Jonathan W., Blakely, Collin M., Pecot, Chad V., Mezquita, Laura, Tabbó, Fabrizio, Scheffler, Matthias, Digumarthy, Subba, Mooradian, Meghan J., Sacher, Adrian G., Lau, Sally C. M., Saltos, Andreas N., Rotow, Julia, Johnson, Rocio Perez, Liu, Corinne, Stewart, Tyler, Goldberg, Sarah B., Killam, Jonathan, Walther, Zenta, Schalper, Kurt, Davies, Kurtis D., Woodcock, Mark G., Anagnostou, Valsamo, Marrone, Kristen A., Forde, Patrick M., Ricciuti, Biagio, Venkatraman, Deepti, Van Allen, Eliezer M., Cummings, Amy L., Goldman, Jonathan W., Shaish, Hiram, Kier, Melanie, Katz, Sharyn, Aggarwal, Charu, Ni, Ying, Azok, Joseph T., Segal, Jeremy, Ritterhouse, Lauren, Neal, Joel W., Lacroix, Ludovic, Elamin, Yasir Y., Negrao, Marcelo V., Le, Xiuning, Lam, Vincent K., Lewis, Whitney E., Kemp, Haley N., Carter, Brett, Roth, Jack A., Swisher, Stephen, Lee, Richard, Zhou, Teng, Poteete, Alissa, Kong, Yifan, Takehara, Tomohiro, Paula, Alvaro Guimaraes, Parra Cuentas, Edwin R., Behrens, Carmen, Wistuba, Ignacio I., Zhang, Jianjun, Blumenschein, George R., Gay, Carl, Byers, Lauren A., Gibbons, Don L., Tsao, Anne, Lee, J. Jack, Bivona, Trever G., Camidge, D. Ross, Gray, Jhannelle E., Lieghl, Natasha, Levy, Benjamin, Brahmer, Julie R., Garassino, Marina C., Gandara, David R., Garon, Edward B., Rizvi, Naiyer A., Scagliotti, Giorgio Vittorio, Wolf, Jürgen, Planchard, David, Besse, Benjamin, Herbst, Roy S., Wakelee, Heather A., Pennell, Nathan A., Shaw, Alice T., Jänne, Pasi A., Carbone, David P., Hellmann, Matthew D., Rudin, Charles M., Albacker, Lee, Mann, Helen, Zhu, Zhou, Lai, Zhongwu, Stewart, Ross, Peters, Solange, Johnson, Melissa L., Wong, Kwok K., Huang, Alan, Winslow, Monte M., Rosen, Michael J., Winters, Ian P., Papadimitrakopoulou, Vassiliki A., Cascone, Tina, Jewsbury, Philip, and Heymach, John V.

Published
2024
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9. Examination of the latent structure of the Ruminative Thoughts Style Questionnaire across countries, gender, and over time

Author

Vidal-Arenas, Verónica, Ibáñez, Manuel I., Ortet-Walker, Jordi, Ortet, Generós, Mezquita, Laura, Bravo, Adrian J., Henson, James M., Pearson, Matthew R., Pilatti, Angelina, Prince, Mark A., Read, Jennifer P., Roozen, Hendrik G., and Ruiz, Paul

Subjects
Psychological tests -- Evaluation, Rumination (Psychology) -- Evaluation, Psychology and mental health
Abstract

The present work aimed to extend the evidence of the structure validity of the Ruminative Thought Style Questionnaire (RTSQ) 15-item version testing: (1) the structure of two competing models (i.e., four-factor correlated model vs a second-order factor model); (2) the measurement invariance of the final model across four countries (U.S., Spain, Argentina, and the Netherlands) and gender groups (male and female); and (3) the invariance across three assessment waves in a subsample of Spanish youths. Participants were college students (mean age = 20.87, SD = 4.47) from the U.S. (n = 1875; 67.1% of females), Spain (T1, n = 732, 63.9% females; T2, n = 370, 71.6% females: T3, n = 307, 60.6% females), Argentina (n = 368, 65.6% females) and the Netherlands (n = 295, 74.8% females). Confirmatory Factor Analyses supported both correlated factors and second-order factor structure in the whole sample. Due to similar fit indices being observed for both models, and considering the theoretical and practical advantages, we kept the second-order model to examine its invariance across groups and time. Measurement invariance analyses showed that the second-order model was invariant across countries, gender, and over time. Comparisons of the total mean score and the subfacet mean scores (i.e., Repetitive Thoughts, Counterfactual Thoughts, Problem-focused Thoughts, and Anticipatory Thoughts) reveled only small differences across country and gender groups. The present work extends the structural validity evidence of the RTSQ, and provides the first evidence concerning its longitudinal stability across time., Author(s): Verónica Vidal-Arenas [sup.1] , Manuel I. Ibáñez [sup.1] [sup.2] , Jordi Ortet-Walker [sup.1] , Generós Ortet [sup.1] [sup.2] , Laura Mezquita [sup.1] [sup.2] , Adrian J. Bravo, James M. [...]

Published
2023
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10. Adverse childhood experiences and adulthood mental health: a cross-cultural examination among university students in seven countries

Author

Kaminer, Debra, Bravo, Adrian J., Mezquita, Laura, Pilatti, Angelina, Conway, Christopher C., Henson, James M., Hogarth, Lee, Ibanez, Manuel I., Keough, Matthew, Ortet, Generos, Pearson, Matthew R., Prince, Mark A., and Read, Jennifer P.

Subjects
College students -- Psychological aspects -- Social aspects -- Health aspects, Life change events -- Research, Mental health -- Social aspects, Psychological research, Ethnopsychology -- Research, Psychology and mental health
Abstract

While there is evidence that histories of adverse childhood experiences (ACEs) are common in university students and are associated with an increased risk of mental health difficulties, current research has limited geographic and cross-cultural representation. Comparing ACEs across diverse contexts using a standardized measure can illuminate geographic and sociocultural similarities or differences in exposure. The present study aimed to assess ACE exposure and its relationship with mental health symptoms in university students from seven countries. We sampled 5945 university students from the United States, Canada, England, South Africa, Spain, Argentina, and Uruguay. Participants completed the Adverse Childhood Experiences International Questionnaire (ACE-IQ) and the Inventory of Depression and Anxiety Symptoms (IDAS). Most participants (94.8%) reported exposure to at least one type of ACE and 61% reported exposure to four or more types. Repeated exposure to at least one ACE was reported by 70.2% and repeated exposure to at least four ACEs was reported by 21.2%. Spanish students had significantly lower ACE exposure than other students. Cumulative ACE exposure was significantly higher among students in lower income countries, but when repeated exposure was considered these differences fell away. For the total sample, cumulative ACE exposure was significantly associated with severity of depression symptoms, anxiety symptoms, and suicidality. Findings indicate that universities globally should be guided by a trauma-informed approach that recognizes students as a psychologically vulnerable group carrying a long-standing burden of childhood adversity., Author(s): Debra Kaminer [sup.1] , Adrian J. Bravo [sup.2] , Laura Mezquita [sup.3] [sup.4] , Angelina Pilatti [sup.5] [sup.6] , Adrian J. Bravo, Christopher C. Conway, James M. Henson, Lee [...]

Published
2023
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12. Determinants of activity and efficacy of anti-PD1/PD-L1 therapy in patients with advanced solid tumors recruited in a clinical trials unit: a longitudinal prospective biomarker-based study

Author

García-Corbacho, Javier, Indacochea, Alberto, González Navarro, Azucena E., Victoria, Iván, Moreno, Débora, Pesántez, David, Angelats, Laura, Modrego-Sanchez, Andrea, Sanfeliu, Esther, Castillo, Oleguer, Blasco, Paula, Mezquita, Laura, Viñolas, Nuria, Nogué, Miquel, Galván, Patricia, Adamo, Barbara, Basté, Neus, Sauri, Tamara, Juan, Manel, Prat, Aleix, and Schettini, Francesco

Published
2023
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13. Association Between Lung Immune Prognostic Index and Durvalumab Consolidation Outcomes in Patients With Locally Advanced Non‐Small‐Cell Lung Cancer

Author

Riudavets, Mariona, Auclin, Edouard, Mosteiro, Miguel, Dempsey, Naomi, Majem, Margarita, Prelaj, Arsela, López-Castro, Rafael, Bosch-Barrera, Joaquim, Pilotto, Sara, Escalera, Elena, Tagliamento, Marco, Mosquera, Joaquin, Zalcman, Gérard, Aboubakar Nana, Frank, Ponce, Santiago, Albarrán-Artahona, Víctor, Dal Maso, Alessandro, Spotti, Martina, Mielgo, Xabier, Mussat, Elodie, Reyes, Roxana, Benítez, Jose-Carlos, Lupinacci, Lorena, Duchemann, Boris, De Giglio, Andrea, Blaquier, Juan Bautista, Audigier-Valette, Clarisse, Scheffler, Matthias, Nadal, Ernest, Lopes, Gilberto, Signorelli, Diego, Garcia-Campelo, Rosario, Menis, Jessica, Bluthgen, Virginia, Campayo, Marc, Recondo, Gonzalo, Besse, Benjamin, Mezquita, Laura, and Planchard, David

Published
2024
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16. Validation of an abridged, 60-item form, of the Junior Spanish NEO inventory (JS NEO-A60)

Author

Ortet-Walker, Jordi, Mezquita, Laura, Vidal-Arenas, Verónica, Ortet, Generós, and Ibáñez, Manuel I.

Subjects
Satisfaction -- Evaluation, High school students -- Testing -- Psychological aspects, Psychological tests -- Evaluation, Psychology and mental health
Abstract

The aim of this study was to develop a 60-item, abridged form of the Junior Spanish version of the NEO-PI-R (JS NEO-A60), consisting of 12 items per dimension. A sample of 399 high school students completed two personality scales to examine the factor structure (Exploratory Structural Equation Model), reliability and convergent validity of the JS NEO-A60. Our sample also completed several consequential life outcome measures in order to examine criterion validity. The five-factor structure, along with representation of the majority of lower-order facets, was satisfactorily covered by the JS NEO-A60. Sources of reliability (internal consistency and test-retest) and validity (convergent) were adequate. The life outcome variables revealed links to personality traits in the expected direction. Namely, internalizing emotional symptoms (anxiety and depression) were mainly predicted by emotional instability. Symptoms of behavioral problems (aggression and antisocial behavior) were predicted by low scores in both agreeableness and conscientiousness. Life satisfaction was significantly predicted by emotional stability. Last, academic performance via students' grades was predicted by conscientiousness and openness. We conclude that the JS NEO-A60 is a sound inventory to assess the five broad personality domains in Spanish-speaking adolescents., Author(s): Jordi Ortet-Walker [sup.1] , Laura Mezquita [sup.1] [sup.2] , Verónica Vidal-Arenas [sup.1] , Generós Ortet [sup.1] [sup.2] , Manuel I. Ibáñez [sup.1] [sup.2] Author Affiliations: (1) grid.9612.c, 0000 0001 [...]

Published
2022
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18. RET-MAP: An International Multicenter Study on Clinicobiologic Features and Treatment Response in Patients With Lung Cancer Harboring a RET Fusion

Author

Aldea, Mihaela, Marinello, Arianna, Duruisseaux, Michael, Zrafi, Wael, Conci, Nicole, Massa, Giacomo, Metro, Giulio, Monnet, Isabelle, Gomez Iranzo, Patricia, Tabbo, Fabrizio, Bria, Emilio, Guisier, Florian, Vasseur, Damien, Lindsay, Colin R., Ponce-Aix, Santiago, Cousin, Sophie, Citarella, Fabrizio, Fallet, Vincent, Minatta, Jose Nicolas, Eisert, Anna, de Saint Basile, Hortense, Audigier-Valette, Clarisse, Mezquita, Laura, Calles, Antonio, Mountzios, Giannis, Tagliamento, Marco, Remon Masip, Jordi, Raimbourg, Judith, Terrisse, Safae, Russo, Alessandro, Cortinovis, Diego, Rochigneux, Philippe, Pinato, David James, Cortellini, Alessio, Leonce, Camille, Gazzah, Anas, Ghigna, Maria-Rosa, Ferrara, Roberto, Dall’Olio, Filippo Gustavo, Passiglia, Francesco, Ludovini, Vienna, Barlesi, Fabrice, Felip, Enriqueta, Planchard, David, and Besse, Benjamin

Published
2023
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20. Second-line treatment outcomes after progression from first-line chemotherapy plus immunotherapy in patients with advanced non-small cell lung cancer

Author

Auclin, Edouard, Benitez-Montanez, Jose, Tagliamento, Marco, Parisi, Francesca, Gorria, Teresa, Garcia-Campelo, Rosario, Dempsey, Naomi, Pinato, David J., Reyes, Roxana, Albarrán-Artahona, Víctor, Dall'Olio, Filippo, Soldato, Davide, Hendriks, Lizza, Nana, Frank Aboubakar, Tonneau, Marion, Lopez-Castro, Rafael, Nadal, Ernest, Kazandjian, Suzanne, Muanza, Thierry, Blanc-Durand, Félix, Fabre, Elizabeth, Castro, Natalia, Arasanz, Hugo, Rochand, Adrien, Besse, Benjamin, Routy, Bertrand, and Mezquita, Laura

Published
2023
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24. Cross-Cultural Examination of the Community Reinforcement Approach Happiness Scale (CRA-HS): Testing measurement invariance in five countries

Author

Roozen, Hendrik G., Bravo, Adrian J., Pilatti, Angelina, Mezquita, Laura, and Vingerhoets, Ad

Subjects
Happiness -- Research -- Social aspects -- Psychological aspects, Mental health -- Influence, Psychology and mental health
Abstract

The Community Reinforcement Approach Happiness Scale (CRA-HS) is widely used for assessing the quality of life in addiction treatment, but the amount of research on the psychometric properties has been scant. The present study sought to (a) test for measurement invariance of the CRA-HS across college students (n = 3388) in five countries (i.e., United States., Spain, Argentina, Uruguay, and the Netherlands); (b) evaluate differences on the CRA-HS (i.e., latent mean differences) as a function of sex and country, and (c) compare criterion-related validity. Using multi-group confirmatory factor analyses, we found a shortened 10-item version of the CRA-HS to be invariant across sex, but only configural and metric invariance was found across countries. Across all countries, criterion-related validity of the CRA-HS scores across different countries emerged. Our findings serve as a foundation for future cross-cultural work testing models in which subjective well-being (i.e., happiness) is an important clinical/routine outcome among college students., Author(s): Hendrik G. Roozen [sup.1] , Adrian J. Bravo [sup.1] , Angelina Pilatti [sup.2] , Laura Mezquita [sup.3] [sup.4] , Ad Vingerhoets [sup.5] Author Affiliations: (1) grid.266832.b, 0000 0001 2188 [...]

Published
2022
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27. Correction to: Determinants of activity and efficacy of anti-PD1/PD-L1 therapy in patients with advanced solid tumors recruited in a clinical trials unit: a longitudinal prospective biomarker-based study

Author

García-Corbacho, Javier, Indacochea, Alberto, González Navarro, Azucena E., Victoria, Iván, Moreno, Débora, Pesántez, David, Angelats, Laura, Modrego-Sanchez, Andrea, Sanfeliu, Esther, Castillo, Oleguer, Blasco, Paula, Mezquita, Laura, Viñolas, Nuria, Nogué, Miquel, Galván, Patricia, Adamo, Barbara, Basté, Neus, Sauri, Tamara, Juan, Manel, Prat, Aleix, and Schettini, Francesco

Published
2023
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30. Clinical Utility and Outcomes Impact of Crystal Digital PCR of Sensitizing and Resistance EGFR Mutations in Patients With Advanced Non-Small Cell Lung Cancer

Author

Riudavets, Mariona, Lamberts, Virginie, Vasseur, Damien, Auclin, Edouard, Aldea, Mihaela, Jovelet, Cécile, Naltet, Charles, Lavaud, Pernelle, Gazzah, Anas, Aboubakar, Frank, Dorta, Miriam, Remon, Jordi, Rouleau, Etienne, Ngocamus, Maud, Nicotra, Claudio, Lacroix, Ludovic, Besse, Benjamin, Mezquita, Laura, and Planchard, David

Published
2022
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41. Cost-Effectiveness of Next-Generation Sequencing Versus Single-Gene Testing for the Molecular Diagnosis of Patients With Metastatic Non–Small-Cell Lung Cancer From the Perspective of Spanish Reference Centers

Author

Arriola, Edurne, Bernabé, Reyes, Campelo, Rosario García, Biscuola, Michele, Enguita, Ana Belén, López-Ríos, Fernando, Martínez, Rafael, Mezquita, Laura, Palanca, Sarai, Pareja, María Jesús, Zugazagoitia, Jon, Arrabal, Natalia, García, J. Francisco, Carcedo, David, and de Álava, Enrique

Published
2023
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43. Cross-national examination of the Distress Tolerance Scale using Rasch methodology.

Author

Oorjitham, Shantini, Medvedev, Oleg N., Bravo, Adrian J., Conway, Christopher C., Henson, James M., Hogarth, Lee, Ibáñez, Manuel I., Kaminer, Debra, Keough, Matthew, Mezquita, Laura, Ortet, Generós, Pearson, Matthew R., Pilatti, Angelina, Prince, Mark A., Read, Jennifer P., Roozen, Hendrik G., and Ruiz, Paul

Subjects
PSYCHOMETRICS, LEGAL evidence, MEDITATION, ADULTS, ALGORITHMS, RASCH models
Abstract

The 15-item Distress Tolerance Scale (DTS) is a widely used psychometric measure with evidence generally supporting its reliability and validity. However, limitations related to its ordinal response format and lack of cross-cultural comparisons have yet to be investigated using appropriate methods. The Partial Credit Rasch model was used to evaluate and enhance the psychometric properties of the DTS using responses from 2550 adult participants from the United States of America (USA), England, Canada, South Africa, Spain, and Argentina. The initial poor fit of the DTS to the Rasch model was improved by removing one item and combining locally dependent items into three testlets. These modifications resulted in the best fit of the 14-item DTS to the Rasch model for all the countries in our study, providing evidence of unidimensionality, high reliability and invariance across countries, meditation practice, and gender. Meeting the expectations of the Rasch model permitted the development of ordinal-to-interval conversion algorithms derived from person estimates of the Rasch model. Using the ordinal-to-interval conversion algorithms published in this article, ordinal DTS scores can be transformed into interval-level data, enhancing the precision of this scale for future research and clinical use across people from the six countries in this study and across the English and Spanish versions of the 14-item DTS. [ABSTRACT FROM AUTHOR]

Published
2024
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44. CD103+CD8+ TRM Cells Accumulate in Tumors of Anti-PD-1-Responder Lung Cancer Patients and Are Tumor-Reactive Lymphocytes Enriched with Tc17

Author

Corgnac, Stéphanie, Malenica, Ines, Mezquita, Laura, Auclin, Edouard, Voilin, Elodie, Kacher, Jamila, Halse, Heloise, Grynszpan, Laetitia, Signolle, Nicolas, Dayris, Thibault, Leclerc, Marine, Droin, Nathalie, de Montpréville, Vincent, Mercier, Olaf, Validire, Pierre, Scoazec, Jean-Yves, Massard, Christophe, Chouaib, Salem, Planchard, David, Adam, Julien, Besse, Benjamin, and Mami-Chouaib, Fathia

Published
2020
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46. Immune Checkpoint Inhibitors Rechallenge Efficacy in Non–Small-Cell Lung Cancer Patients

Author

Gobbini, Elisa, Toffart, Anne Claire, Pérol, Maurice, Assié, Jean-Baptiste, Duruisseaux, Michaël, Coupez, Dahna, Dubos, Catherine, Westeel, Virginie, Delaunay, Myriam, Guisier, Florian, Veillon, Rémi, Gounant, Valérie, Giroux Leprieur, Etienne, Vanel, François-Roger, Chaabane, Nouha, Dansin, Eric, Babey, Hélène, Decroisette, Chantal, Barlesi, Fabrice, Daniel, Catherine, Fournel, Pierre, Mezquita, Laura, Oulkhouir, Youssef, Canellas, Anthony, Duchemann, Boris, Molinier, Olivier, Alcazer, Vincent, Moro-Sibilot, Denis, and Levra, Matteo Giaj

Published
2020
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47. Immune Checkpoint Inhibitors in Thoracic Malignancies: Review of the Existing Evidence by an IASLC Expert Panel and Recommendations

Author

Remon, Jordi, Passiglia, Francesco, Ahn, Myung-Ju, Barlesi, Fabrice, Forde, Patrick M., Garon, Edward B., Gettinger, Scott, Goldberg, Sarah B., Herbst, Roy S., Horn, Leora, Kubota, Kaoru, Lu, Shun, Mezquita, Laura, Paz-Ares, Luis, Popat, Sanjay, Schalper, Kurt A., Skoulidis, Ferdinandos, Reck, Martin, Adjei, Alex A., and Scagliotti, Giorgio V.

Published
2020
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49. Circulating Tumor DNA Analysis for Patients with Oncogene-Addicted NSCLC With Isolated Central Nervous System Progression

Author

Aldea, Mihaela, Hendriks, Lizza, Mezquita, Laura, Jovelet, Cécile, Planchard, David, Auclin, Edouard, Remon, Jordi, Howarth, Karen, Benitez, Jose Carlos, Gazzah, Anas, Lavaud, Pernelle, Naltet, Charles, Lacroix, Ludovic, de Kievit, Frank, Morris, Clive, Green, Emma, Ngo-Camus, Maud, Rouleau, Etienne, Massard, Christophe, Caramella, Caroline, Friboulet, Luc, and Besse, Benjamin

Published
2020
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