1. Efficacy of Tube Feeding in Binge-Eating/Vomiting Patients
- Author
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Marie-Claude Brindisi, Daniel Rigaud, Anne Roblot, Bruno Vergès, Véronique Brayer, Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Service d'endocrinologie et nutrition, Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Centre des Sciences du Goût et de l'Alimentation [Dijon] ( CSGA ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ), and Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand ( CHU Dijon )
- Subjects
Pediatrics ,Hamilton Anxiety Rating Scale ,[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutrition ,medicine.medical_treatment ,Medicine (miscellaneous) ,Anxiety ,Anorexia nervosa ,law.invention ,MESH : Anxiety ,Randomized controlled trial ,MESH : Depression ,MESH: Vomiting ,law ,MESH : Vomiting ,Bulimia ,MESH : Muscle, Skeletal ,MESH: Treatment Outcome ,media_common ,MESH: Muscle, Skeletal ,Nutrition and Dietetics ,MESH : Bulimia Nervosa ,Depression ,Bulimia nervosa ,Body Fluid Compartments ,MESH : Adult ,Cognitive behavioral therapy ,Eating disorders ,Treatment Outcome ,MESH: Young Adult ,MESH : Cognitive Therapy ,MESH : Bulimia ,Adult ,MESH: Enteral Nutrition ,medicine.medical_specialty ,MESH: Depression ,Vomiting ,media_common.quotation_subject ,MESH : Young Adult ,MESH : Treatment Outcome ,behavioral disciplines and activities ,Young Adult ,Enteral Nutrition ,MESH: Body Fluid Compartments ,mental disorders ,medicine ,Humans ,MESH : Body Fluid Compartments ,MESH: Bulimia ,Bulimia Nervosa ,Muscle, Skeletal ,MESH: Humans ,Cognitive Behavioral Therapy ,MESH: Anxiety ,business.industry ,MESH : Humans ,MESH: Biological Markers ,Beck Depression Inventory ,MESH: Quality of Life ,MESH: Adult ,MESH : Quality of Life ,Abstinence ,medicine.disease ,MESH: Cognitive Therapy ,Surgery ,MESH : Biological Markers ,MESH : Enteral Nutrition ,Quality of Life ,business ,MESH: Bulimia Nervosa ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,Biomarkers - Abstract
International audience; BACKGROUND: In many binge-eating/vomiting patients, abstinence could not be obtained from classical treatments. Since the authors showed that tube feeding (TF) reduced such episodes in anorexia nervosa (AN)-hospitalized patients, they carried out a randomized trial on the efficacy of TF plus cognitive behavioral therapy (CBT) vs CBT alone in AN and bulimia nervosa adult outpatients. METHODS: The authors randomly assigned 103 ambulatory patients to receive 16 sessions of CBT alone (n = 51) or CBT plus 2 months of TF (n = 52). The main goal was abstinence of binge-eating/vomiting episodes. Other criteria were gains in fat-free mass and muscle mass improvements in nutrition markers, and quality of life (SF-36 Health Survey), depression (Beck Depression Inventory), and anxiety (Hamilton Anxiety Rating Scale) scores. Evaluations were performed at 1, 2 (end of treatment), 5, 8, and 14 months (analysis of variance). RESULTS: TF patients were rapidly and more frequently abstinent at the end of treatment (2 months) than the CBT patients: 81% vs 29% (P < .001). Fat-free mass, biological markers, depressive state (-58% vs -26%), anxiety (-48% vs -15%), and quality of life (+42% vs +13%) were more improved in the TF group than in the CBT group (P < .05). One year later, more TF patients remained abstinent (68% vs 27%, P = .02); they were less anxious, were less depressed, and had better quality of life than the CBT patients (P < .05). CONCLUSION: TF combined with CBT offered better results than CBT alone.
- Published
- 2011
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