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Stafne cyst, named after Edward Stafne, was first described in 1942 when he noticed asymptomatic radiolucent cavities in intraoral radiographs of 35 different patients. It is usually a well-defined, round, ovoid or occasionally lobulated radiolucency of size 1–3 cm typically located in the submandibular gland fossa. In this paper, we present two cases of Stafne cyst, one with an unusual presentation having trapezoid-shaped radiolucency with scalloped margin involving the inferior border of the mandible and another with the usual presentation. In both the cases, diagnosis was based on clinical and radiological features alone without any surgical exploration. With the condition remaining static throughout the follow-up period, it is proven that noninvasive diagnostic radiography such as computed tomography scan with three-dimensional reconstruction and cone beam computed tomography can be very helpful for the definite diagnosis of Stafne cyst, rather than invasive procedures.

Crouzon syndrome is the most common syndrome among the craniosynostosis group. Crouzon syndrome accounts for about 4.8% of all of them. It commonly has autosomal dominant inheritance with complete penetrance and variable expressivity from subtle to severe forms and characterized by craniosynostosis, exophthalmos, and hypoplastic maxilla with relative mandibular prognathism. Mutation of the fibroblast growth factor receptor-2 gene is responsible for the occurrence of this rare genetic disorder. Our paper reports the diagnosis of this rare syndrome in a young female patient based on clinical and radiographical features. Prompt and timely management of the syndrome has enabled this patient to lead a normal life despite the syndrome.

Langerhans cell histiocytosis (LCH) is characterized histologically by a monoclonal proliferation of large mononuclear cells accompanied by a prominent eosinophil infiltrate. The pathogenesis of LCH is unknown. Hand–Schuller–Christian (HSC) disease is a rare proliferative disorder in which pathological Langerhans cells (LCs) accumulate in various organs. The clinical manifestations arise as a result of accumulation and infiltration of the Langerhans cells in organs and tissues. HSC is characterized by a classic triad of exophthalmos, diabetes insipidus, and lytic lesions in the skull. It is usually manifested in children but can also affect adults. Here, we present a case of HSC disease in a 12-year-old boy with oral manifestations.