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1. Asthma management and control in children, adolescents, and adults in 25 countries: a Global Asthma Network Phase I cross-sectional study

Author

Ahmetaj, Luljeta N., Ajeagah, Gideon A., Alkhayer, Ghroob, Alomary, Shaker A., Ambriz-Moreno, Maria J., Arias-Cruz, Alfredo, Awasthi, Shally, Badellino, Hector, Behniafard, Nasrin, Bercedo-Sanz, Alberto, Brożek, Grzegorz, Bucaliu-Ismajli, Ibadete, Cabrera-Aguilar, Angela, Chinratanapisit, Sasawan, Del-Río-Navarro, Blanca E., Douros, Kostas, El Sadig, Hana, Escalante-Dominguez, Alberto J., Falade, Adegoke G., Gacaferri-Lumezi, Besa, García-Almaráz, Roberto, Garcia-Muñoz, Rosa, Ghashi, Valbona, Ghoshal, Aloke G., González-Díaz, Carlos, Hana-Lleshi, Leonora, Hernández-Mondragón, Luis O., Huang, Jing-Long, Jiménez-González, Carlos A., Juan-Pineda, M. Ángeles, Kochar, Sanjay K., Kuzmicheva, Kseniiay, Linares-Zapien, Francisco J., Lokaj-Berisha, Violeta, López-Silvarrey, Angel, Lozano-Sáenz, José S., Mahesh, Padukudru A., Mallol, Javier, Martinez-Torres, Antonia E., Masekela, Refiloe, Mérida-Palacio, J. Valente, Mohammad, Yousser, Moreno-Gardea, Héctor L., Navarrete-Rodriguez, Elsy M., Ndikum, Achiri E., Noor, Magde, Ochoa-Lopez, Georgina, Pajaziti, Laura, Pellegrini-Belinchon, Javier, Perez-Fernández, Virginia, Priftis, Kostas, Ramos-García, Beatriz C., Ranasinghe, Jagath C., Robertson, Steve, Rodriguez-Perez, Noel, Rutter, Charlotte E., Sacre-Hazouri, José A., Salvi, Sundeep, Sanchez, Javier F., Sánchez, José F., Sanchez-Coronel, Maria G., Saucedo-Ramirez, Omar J., Singh, Meenu, Singh, Nishtha, Singh, Virendra, Sinha, Sanjeev, Sit, Niranjan, Sosa-Ferrari, Suyapa M., Soto-Martínez, Manuel E., Urrutia-Pereira, Marylin, Yeh, Kuo-Wei, Zar, Heather J., Zhjeqi, Valbona, García-Marcos, Luis, Chiang, Chen-Yuan, Asher, M Innes, Marks, Guy B, El Sony, Asma, Bissell, Karen, Ellwood, Eamon, Ellwood, Philippa, Pearce, Neil, Strachan, David P, Mortimer, Kevin, and Morales, Eva

Published
2023
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2. Associated factors with recurrent wheezing in infants: is there difference between the sexes?

Author

Ferreira, Wellington Fernando da Silva, Carvalho, Denise Siqueira de, Wandalsen, Gustavo Falbo, Solé, Dirceu, Sarinho, Emanuel Sávio Cavalcante, Medeiros, Décio, Melo, Ana Carolina Cavalcanti Dela Bianca, Prestes, Elaine Xavier, Camargos, Paulo Augusto Moreira, Luhm, Karin Regina, Garcia-Marcos, Luis, Mallol, Javier, Rosário, Nelson Augusto, and Chong-Neto, Herberto José

Published
2021
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3. Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study

Author

Bissell, Karen, Chiang, Chen-Yuan, Ellwood, Eamon, Ellwood, Philippa, Marks, Guy B, Masekela, Refiloe, Morales, Eva, Mortimer, Kevin, Pearce, Neil, Strachan, David, Martinez-Torres, Antonela, Pérez-Fernández, Virginia, Robertson, Stephen, Rutter, Charlotte, Silverwood, Richard, Mallol, Javier, Soto-Martínez, Manuel, Cabrera Aguilar, Angelita, Douros, Konstantinos, Sabir, Mohammed, Singh, Meenu, Singh, Virendra, Sukumaran, Thevaruparambil Unny, Awasthi, Shally, Kabra, Sushil Kumar, Salvi, Sundeep, García-Almaráz, Roberto, Mérida-Palacio, J. Valente, Del Río Navarro, Blanca E, González-Díaz, Sandra Nora, Navarrete-Rodriguez, Elsy Maureen, Sánchez, José Félix, Falade, Adegoke G, Zar, Heather J, López-Silvarrey Varela, Angel, González Díaz, Carlos, Nour, Magde, Dib, Gazal, Mohammad, Yousser, Huang, Jing-Long, Chinratanapisit, Sasawan, Soto-Quirós, Manuel E, Vichyanond, Pakit, Aguilar, Pedro, Barba, Sergio, Kumar, Lata, Sharma, S K, Linares-Zapién, Francisco J, Onadeko, Babatunde O, Musa, Omer Abdel Aziz, Aguirre, Viviana, Baeza-Bacab, Manuel, Mohammad, Samira, Cortez, Eliana, Gratziou, Christina H, Chopra, Kamlesh, Hanumante, Neeta Milind, Nelson, Hugo, Rubio, Alfonso Delgado, Hsieh, Kue-Hsiung, Shah, Jayant, Asher, M Innes, Rutter, Charlotte E, El Sony, Asma, García-Marcos, Luis, Robertson, Steven, Silverwood, Richard J, and Strachan, David P

Published
2021
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4. Differences in percentage predicted spirometric values obtained with thirteen reference equations applied to healthy children.

Author

Aguirre-Camposano, Viviana and Mallol, Javier

Subjects
*POSTRACIALISM, *CHILD patients, *CHILEANS, *FORCED expiratory volume
Abstract

AbstractBackgroundObjectiveMethodsResultsConclusionsThere is limited information on the discrepancy between the spirometric values calculated with diverse spirometric prediction equations in normal children.To determine the differences in percentage predicted (PP) values calculated through thirteen prediction equations (PEs) in healthy Chilean children.We compared the PP values for FVC, FEV1, FEF25–75% and FEV1/FVC obtained by applying thirteen PEs, using GLI-2012 as a gold standard reference equation and including race neutral GLI-2022 in the analysis; PP values are from a group of 208 healthy Chilean children aged 7 to 17 years.In boys, the range of differences for FVC between PEs compared to the reference group went from −5.47% to 20.82% and from −6.4% to 19.74% in girls. For FEV1, in girls, the range of differences went from −5.96% to 18.01% and from −5,04% to 20.67% in boys. Significant differences between GLI-2012 PPs and the other PEs were observed more frequently in girls than in boys (p < 0.001).There is a wide difference between the spirometric PPs values by different PEs, including race neutral GLI-2022. Our findings, especially given the potential interpretative and clinical implications, might suggest the need for conducting standardized, multicenter studies in Latin America to determine which PEs would better fit pediatric populations in this region. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Asthma management and control in children, adolescents, and adults in 25 countries: a Global Asthma Network Phase I cross-sectional study

Author

García-Marcos, Luis, primary, Chiang, Chen-Yuan, additional, Asher, M Innes, additional, Marks, Guy B, additional, El Sony, Asma, additional, Masekela, Refiloe, additional, Bissell, Karen, additional, Ellwood, Eamon, additional, Ellwood, Philippa, additional, Pearce, Neil, additional, Strachan, David P, additional, Mortimer, Kevin, additional, Morales, Eva, additional, Ahmetaj, Luljeta N., additional, Ajeagah, Gideon A., additional, Alkhayer, Ghroob, additional, Alomary, Shaker A., additional, Ambriz-Moreno, Maria J., additional, Arias-Cruz, Alfredo, additional, Awasthi, Shally, additional, Badellino, Hector, additional, Behniafard, Nasrin, additional, Bercedo-Sanz, Alberto, additional, Brożek, Grzegorz, additional, Bucaliu-Ismajli, Ibadete, additional, Cabrera-Aguilar, Angela, additional, Chinratanapisit, Sasawan, additional, Del-Río-Navarro, Blanca E., additional, Douros, Kostas, additional, El Sadig, Hana, additional, Escalante-Dominguez, Alberto J., additional, Falade, Adegoke G., additional, Gacaferri-Lumezi, Besa, additional, García-Almaráz, Roberto, additional, Garcia-Muñoz, Rosa, additional, Ghashi, Valbona, additional, Ghoshal, Aloke G., additional, González-Díaz, Carlos, additional, Hana-Lleshi, Leonora, additional, Hernández-Mondragón, Luis O., additional, Huang, Jing-Long, additional, Jiménez-González, Carlos A., additional, Juan-Pineda, M. Ángeles, additional, Kochar, Sanjay K., additional, Kuzmicheva, Kseniiay, additional, Linares-Zapien, Francisco J., additional, Lokaj-Berisha, Violeta, additional, López-Silvarrey, Angel, additional, Lozano-Sáenz, José S., additional, Mahesh, Padukudru A., additional, Mallol, Javier, additional, Martinez-Torres, Antonia E., additional, Mérida-Palacio, J. Valente, additional, Mohammad, Yousser, additional, Moreno-Gardea, Héctor L., additional, Navarrete-Rodriguez, Elsy M., additional, Ndikum, Achiri E., additional, Noor, Magde, additional, Ochoa-Lopez, Georgina, additional, Pajaziti, Laura, additional, Pellegrini-Belinchon, Javier, additional, Perez-Fernández, Virginia, additional, Priftis, Kostas, additional, Ramos-García, Beatriz C., additional, Ranasinghe, Jagath C., additional, Robertson, Steve, additional, Rodriguez-Perez, Noel, additional, Rutter, Charlotte E., additional, Sacre-Hazouri, José A., additional, Salvi, Sundeep, additional, Sanchez, Javier F., additional, Sánchez, José F., additional, Sanchez-Coronel, Maria G., additional, Saucedo-Ramirez, Omar J., additional, Singh, Meenu, additional, Singh, Nishtha, additional, Singh, Virendra, additional, Sinha, Sanjeev, additional, Sit, Niranjan, additional, Sosa-Ferrari, Suyapa M., additional, Soto-Martínez, Manuel E., additional, Urrutia-Pereira, Marylin, additional, Yeh, Kuo-Wei, additional, Zar, Heather J., additional, and Zhjeqi, Valbona, additional

Published
2023
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15. Incendios forestales: ¿la punta del iceberg para la salud planetaria?

Author

Pereira, Marilyn Nilda Esther Urrutia de, primary, Fogelbach, Guillhermo Guidos, additional, Mallol, Javier, additional, Staffel, Patricia Latour, additional, Sarabia, Alfonso Mario Cepeda, additional, Ramirez, Maria Susana Repka, additional, Serrate, Mario Paz, additional, Llosa, Oscar Calderón, additional, Coello, Mabel, additional, Acosta, Veronica, additional, Wasenius, Silvina, additional, Chong Neto, Herberto Jose, additional, and Solé, Dirceu, additional

Published
2022
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22. Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study

Author

Asher, M Innes, primary, Rutter, Charlotte E, additional, Bissell, Karen, additional, Chiang, Chen-Yuan, additional, El Sony, Asma, additional, Ellwood, Eamon, additional, Ellwood, Philippa, additional, García-Marcos, Luis, additional, Marks, Guy B, additional, Morales, Eva, additional, Mortimer, Kevin, additional, Pérez-Fernández, Virginia, additional, Robertson, Steven, additional, Silverwood, Richard J, additional, Strachan, David P, additional, Pearce, Neil, additional, Masekela, Refiloe, additional, Strachan, David, additional, Martinez-Torres, Antonela, additional, Robertson, Stephen, additional, Rutter, Charlotte, additional, Silverwood, Richard, additional, Mallol, Javier, additional, Soto-Martínez, Manuel, additional, Cabrera Aguilar, Angelita, additional, Douros, Konstantinos, additional, Sabir, Mohammed, additional, Singh, Meenu, additional, Singh, Virendra, additional, Sukumaran, Thevaruparambil Unny, additional, Awasthi, Shally, additional, Kabra, Sushil Kumar, additional, Salvi, Sundeep, additional, García-Almaráz, Roberto, additional, Mérida-Palacio, J. Valente, additional, Del Río Navarro, Blanca E, additional, González-Díaz, Sandra Nora, additional, Navarrete-Rodriguez, Elsy Maureen, additional, Sánchez, José Félix, additional, Falade, Adegoke G, additional, Zar, Heather J, additional, López-Silvarrey Varela, Angel, additional, González Díaz, Carlos, additional, Nour, Magde, additional, Dib, Gazal, additional, Mohammad, Yousser, additional, Huang, Jing-Long, additional, Chinratanapisit, Sasawan, additional, Soto-Quirós, Manuel E, additional, Vichyanond, Pakit, additional, Aguilar, Pedro, additional, Barba, Sergio, additional, Kumar, Lata, additional, Sharma, S K, additional, Linares-Zapién, Francisco J, additional, Onadeko, Babatunde O, additional, Musa, Omer Abdel Aziz, additional, Aguirre, Viviana, additional, Baeza-Bacab, Manuel, additional, Mohammad, Samira, additional, Cortez, Eliana, additional, Gratziou, Christina H, additional, Chopra, Kamlesh, additional, Hanumante, Neeta Milind, additional, Nelson, Hugo, additional, Rubio, Alfonso Delgado, additional, Hsieh, Kue-Hsiung, additional, and Shah, Jayant, additional

Published
2021
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32. Author response

Author

Larenas-Linnemann, Désirée, primary, Romero-Tapia, Sergio, additional, Virgen, Cesar, additional, Mallol, Javier, additional, Baeza Bacab, Manuel Antonio, additional, and García-Marcos, Luis, additional

Published
2020
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35. TEMPORAL COMPARISON OF WHEEZING PREVALENCE IN THE FIRST YEAR OF LIFE IN SÃO PAULO: INTERNATIONAL STUDY OF WHEEZING IN INFANTS

Author

Aranda, Carolina Sanchez, Wandalsen, Gustavo Falbo, Bianca, Ana Caroline Cavalcanti Dela, Dantas, Ellen de Oliveira, Mallol, Javier, and Solé, Dirceu

Subjects
Male, Lactente, Sons respiratórios, Internationality, Time Factors, Infant, Respiratory sounds/wheezing, Severity of Illness Index, Prevalence, Humans, Original Article, Prevalência, Female, Asthma, Asma, Brazil, Respiratory Sounds
Abstract

To assess the prevalence and severity of wheezing in the first year of life of infants, using the standardized protocol of the Estudio Internacional de Sibilancias en Lactantes- phase 3, and compare the values obtained with those found in phase 1, conducted at the same center.Between 2009 and 2010, parents and guardians of infants answered the written questionnaire of the Estudio Internacional de Sibilancias en Lactantes - phase 3, and its results were compared to those of phase 1, performed between 2005 and 2006. We divided the infants into wheezing and non-wheezing. The wheezing group was stratified according to the frequency of episodes: occasional wheezing - less than three -, and recurrent wheezing - three or more.Wheezing prevalence was similar in both phases (44.6 versus 46%). Regarding frequency, the prevalence of occasional wheezing increased (19.4 versus 23%; p=0.03) and recurrent wheezing decreased (26.7 versus 21.6%; p=0.005). Also, diagnosis of asthma (7.5 versus 21.8%), use of inhaled corticosteroids (11.7 versus35%), and hospitalization for wheezing (19.7 versus 32.6%) grew significantly in phase 3. This period coincides with the Influenza A (H1N1) pandemic, which could have contributed to this outcome.Wheezing prevalence in the first year of life remains high. Despite the temporal assessment showing a decrease in the prevalence of recurrent wheezing, a significant increase in its morbidity was identified due to the higher number of hospitalizations. In addition, there were signs of improvement in the wheezing management of infants, reflected by an increase in the diagnosis of asthma and a greater indication of preventive treatments.Avaliar a prevalência e a gravidade da sibilância em lactentes no primeiro ano de vida, utilizando o protocolo padronizado do Estudio Internacional de Sibilancias en Lactantes- fase 3, e comparar os valores obtidos com os observados no Estudio Internacional de Sibilancias en Lactantes- fase 1, realizado no mesmo centro.Entre 2009 e 2010, pais e responsáveis de lactentes responderam ao questionário escrito do Estudio Internacional de Sibilancias en Lactantes- fase 3, e os resultados obtidos foram comparados aos do Estudio Internacional de Sibilancias en Lactantes- fase 1, realizado entre 2005 e 2006. Oslactentes foram separados em sibilantes e “não sibilantes”. Osprimeiros foram divididos de acordo com a frequência dos episódios: sibilância ocasional, quando apresentaram menos de três, e sibilância recorrente, quando manifestaram três ou mais.A prevalência de sibilantes foi similar nas duas fases (44,6 versus46%). Segundo a frequência, houve aumento na prevalência de sibilância ocasional (19,4 versus 23%; p=0,03) e redução na de sibilância recorrente (26,7 versus 21,6%; p=0,005). Observou-se, ainda, aumento expressivo no diagnóstico de asma (7,5 versus 21,8%) e no uso de corticosteroides inalatórios (11,7 versus 35%), como também na hospitalização por sibilância na fase 3 (19,7 versus 32,6%), período da pandemia Influenza A (H1N1), o que pode ter contribuído para este desfecho.A prevalência da sibilância no primeiro ano de vida permanece elevada. Apesar de a avaliação temporal mostrar queda na prevalência da sibilância recorrente, aumento significante de sua morbidade foi identificado pelo maior número de hospitalizações. Além disso, houve indícios de melhora no manejo da sibilância dos lactentes, refletido pelo aumento do diagnóstico de asma e maior indicação de tratamentos preventivos.

Published
2018

42. Associated factors with recurrent wheezing in infants: is there difference between the sexes?

Author

da Silva Ferreira, Wellington Fernando, Siqueira de Carvalho, Denise, Falbo Wandalsen, Gustavo, Solé, Dirceu, Cavalcante Sarinho, Emanuel Sávio, Med, Décio, Cavalcanti Dela Bianca Melo, Ana Carolina, Xavier Prestes, Elaine, Moreira Camargos, Paulo Augusto, Regina Luhm, Karin, Garcia-Marcos, Luis, Mallol, Javier, Augusto Rosário, Nelson, and José Chong-Neto, Herberto

Subjects
WHEEZE, NEWBORN infants, IMMUNIZATION, CORTICOSTEROIDS, BRONCHODILATOR agents, GENDER differences (Psychology)
Abstract

Objective: Identify associated factors for recurrent wheezing (RW) in male and female infants. Methods: Cross-sectional multicentric study using the standardized questionnaire from the Estudio Internacional sobre Sibilancias en Lactantes (EISL). The questionnaire was applied to parents of 9345 infants aged 12--15 months at the time of immunization/routine visits. Results: One thousand two hundred and sixty-one (13.5%) males and nine hundred sixty-three (10.3%) females have had RW (=3 episodes), respectively (p10 colds episodes (OR = 3.46; IC 95% 2.35--5.07), air pollution (OR = 1.33; IC 95% 1.12--1.59), molds at home (OR = 1.23; IC 95% 1.03--1.47), Afro-descendants (OR = 1.42; IC 95% 1.20--1.69), bronchopneumonia (OR = 1.41; IC; 1.11--1.78), severe episodes of wheezing in the first year (OR = 1.56; IC 95% 1.29--1.89), treatment with bronchodilators (OR = 1.60; IC 95% 1.22--2,1) and treatment with oral corticosteroids (OR = 1,23; IC 95% 0.99--1,52). Associated factors for RW for females were passive smoking (OR = 1.24; IC 95% 1.01-1,51), parents diagnosed with asthma (OR = 1.32; IC 95% 1,08-1,62), parents with allergic rhinitis (OR = 1.26; IC 95% 1.04--1.53), daycare attendance (OR = 1.48; IC 95% 1.17-1,88), colds in the first 6 months of life (OR = 2.19; IC 95% 1.69--2.82), personal diagnosis of asthma (OR = 1.84; IC 95% 1.39--2.44), emergency room visits (OR = 1.78; IC 95% 1.44--2.21), nighttime symptoms (OR = 2.89; IC 95% 2.34--3.53) and updated immunization (OR = 0.62; IC 95% 0.41-0.96). Conclusion: There are differences in associated factors for RW between genders. Identification of these differences could be useful to the approach and management of RW between boys and girls. [ABSTRACT FROM AUTHOR]

Published
2021
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44. Worldwide variations in the prevalence of symptoms of atopic eczema in the international study of asthma and allergies in childhood

Author

Williams, Hywel, Robertson, Colin, Stewart, Alistair, Aït-Khaled, Nadia, Anabwani, Gabriel, Anderson, Ross, Asher, Innes, Beasley, Richard, Björkstén, Bengt, Burr, Michael, Clayton, Tadd, Crane, Julian, Ellwood, Philippa, Keil, Ulrich, Lai, Chris, Mallol, Javier, Martinez, Fernando, Mitchell, Edwin, Montefort, Stephen, Pearce, Neil, Shah, Jayant, Sibbald, Bonnie, Strachan, David, von Mutius, Erika, and Weiland, Stephan K.

Published
1999

45. Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One

Author

Asher M Innes, Stewart Alistair W, Mallol Javier, Montefort Stephen, Lai Christopher KW, Aït-Khaled Nadia, and Odhiambo Joseph

Subjects
Diseases of the respiratory system, RC705-779
Abstract

Abstract The International Study of Asthma and Allergies in Childhood (ISAAC) Phase One showed large worldwide variations in the prevalence of symptoms of asthma, rhinoconjunctivitis and eczema, up to 10 to 20 fold between countries. Ecological analyses were undertaken with ISAAC Phase One data to explore factors that may have contributed to these variations, and are summarised and reviewed here. In ISAAC Phase One the prevalence of symptoms in the past 12 months of asthma, rhinoconjunctivitis and eczema were estimated from studies in 463,801 children aged 13 - 14 years in 155 centres in 56 countries, and in 257,800 children aged 6-7 years in 91 centres in 38 countries. Ecological analyses were undertaken between symptom prevalence and the following: Gross National Product per capita (GNP), food intake, immunisation rates, tuberculosis notifications, climatic factors, tobacco consumption, pollen, antibiotic sales, paracetamol sales, and outdoor air pollution. Symptom prevalence of all three conditions was positively associated with GNP, trans fatty acids, paracetamol, and women smoking, and inversely associated with food of plant origin, pollen, immunisations, tuberculosis notifications, air pollution, and men smoking. The magnitude of these associations was small, but consistent in direction between conditions. There were mixed associations of climate and antibiotic sales with symptom prevalence. The potential causality of these associations warrant further investigation. Factors which prevent the development of these conditions, or where there is an absence of a positive correlation at a population level may be as important from the policy viewpoint as a focus on the positive risk factors. Interventions based on small associations may have the potential for a large public health benefit.

Published
2010
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46. Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC)

Author

Strachan, David, Sibbald, Bonnie, Weiland, Stephan, Aït-Khaled, Nadia, Anabwani, Gabriel, Anderson, H. Ross, Asher, M. Innes, Beasley, Richard, Björkstén, Bengt, Burr, Michael, Clayton, Tadd, Crane, Julian, Ellwood, Philippa, Keil, Ulrich, Lai, Christopher, Mallol, Javier, Martinez, Fernando, Mitchell, Edwin, Montefort, Stephen, Pearce, Neil, Robertson, Colin, Shah, Jayant, Stewart, Alistair, von Mutius, Erika, and Williams, Hywel

Published
1997

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