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This paper presents a review of the working principle, the development and the research progress of the quartz tuning fork micromachined gyroscopes. Then, the fabrication process, the performance parameters and the application fields of the QRS are illustrated. Next, the development trends and the existing problems are analyzed, including the uneven crystal edges of the quartz sidewall caused by the fabrication process, the confined etchant layer technology and the electrode fabrication technique. In summary, the QRSs are widely applied in many fields, including military and commercial applications, because of its small size, lightweight, low power consumption, high resistance to overload and availability in harsh environments. Keywords-Coriolis acceleration; piezoelectric effect; quartz tuning fork; micromachined gyroscope; anisotropic etching

Every function of product comes from the demand of user.Designers can use UCD philosophy get more effective information and true requirements from users. This paper first discusses the characteristics of UCD, and why it should be used in design. After comparing Android devices and desktop computers, this paper listed outconsiderations for Android devices in design. Then it gives some suggestions on steps and tools for design Android app in UCD. Keywords-UCD; android; App; design

Carcinoembryonic antigen (CEA) and CEA family member CEACAM6 are glycophosphatidyl inositol (GPI)-anchored, intercellular adhesion molecules that are up-regulated in a wide variety of human cancers, including colon, breast, and lung. When over-expressed in a number of cellular systems, these molecules are capable of inhibiting cellular differentiation and anoikis, as well as disrupting cell polarization and tissue architecture, thus increasing tumorigenicity. The present study shows that perturbation of the major fibronectin receptor, integrin α5β1, underlies some of these biological effects. Using confocal microscopy and specific antibodies, CEA and CEACAM6 were demonstrated to co-cluster with integrin α5β1 on the cell surface. The presence of CEA and CEACAM6 was shown to lead to an increase in the binding of the integrin α5β1 receptor to its ligand fibronectin, without changing its cell surface levels, resulting in increased adhesion of CEA/CEACAM6-expressing cells to fibronectin. More tenacious binding of free fibronectin to cells led to enhanced fibronectin matrix assembly and the formation of a polymerized fibronectin “cocoon” around the cells. Disruption of this process with specific monoclonal antibodies against either fibronectin or integrin α5β1 led to the restoration of cellular differentiation and anoikis in CEA/CEACAM6 producing cells. J. Cell. Physiol. 210: 757–765, 2007. © 2006 Wiley-Liss, Inc.

The small 11-kDa proteins of B19 parvovirus contain three proline-rich regions which conform to consensus Src homology 3 (SH3) ligand sequences present in signaling molecules within the cell. We have shown that the B19 11-kDa proteins specifically interact with the growth factor receptor-binding protein 2 (Grb2) in vitro. Mutation of prolines within one of the three SH3 ligand-like sequences decreases the binding of B19 11-kDa proteins to Grb2, suggesting that the proline-rich region is involved in the B19 11-kDa/Grb2 interaction. Therefore, the B19 11-kDa proteins may function to alter Grb2-mediated signaling by disrupting SH3 domain/ligand interactions. These results implicate the 11-kDa proteins in B19 pathogenesis through perturbation of normal cellular signaling pathways.

System errors (such as sensor response, location, or gain/phase errors between channels) would greatly degrade the DBF performance because the array data did not match with the ideal model assumed. Dogan, Gonen, and Mendel (see IEEE Trans. on AES. vol.30, no.3, p.722-41, 1994, IEEE Trans. on SP, vol.43, no.5, p.1200-16, 1995 and Proc. of IEEE Interl. Conf. on ASSP, p.1908-11, 1995) proposed the blind beamforming method, it provided a new idea to obtain a better DBF performance. Liao, Guisheng et al. (see Journal of China Institute of Communications, vol.17, no.4, p.9-14, 1996) proposed a cumulant-based method to estimate the supperresolution DOA of the desired signals. This paper refers to the method to solve the blind DBF problem, and uses it in an experimental bistatic radar to achieve pulse chasing. Some results are showed, and compared with a conventional method GSO (Gram-Schmidt orthogonalization).