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RESUMO O objetivo desse estudo foi observar a ação da romã (Punica granatum L.) em estomatites induzidas por queimaduras no dorso da língua de ratos Wistar. Foram utilizados 24 ratos Wistar machos adultos, provenientes do Biotério da UNIVASF. Foram formados quatro grupos (G1: Polpa da romã por gavagem; G2: Polpa da romã por gavagem + aplicação local do chá da casca do fruto; G3: aplicação local do chá da casca do fruto e G4: Controle negativo). As queimaduras foram confeccionadas com instrumental odontológico padrão. Os tratamentos foram realizados duas vezes ao dia, durante 14 dias. Metade dos animais de cada grupo (n=3) foi eutanasiada no sétimo dia de experimentação, enquanto o restante foi eutanasiado no 14º dia. As línguas foram removidas e fixadas com formaldeído a 10% tamponado, processadas com cortes de 5 µm e coradas em HE. Clinicamente, os animais do grupo G2 tiveram melhores resultados. Na análise histológica qualitativa foi avaliada a reepitelização e os graus de inflamação numa escala de 0 a 4. Na análise estatística, utilizou-se o teste Qui-quadrado de Pearson. Houve significância estatística (p=0,026 e p=0,023) quando se comparou o tratamento com os graus de reepitelização e inflamação nos quatro grupos estudados. O grupo G2 apresentou cicatrização completa com 14 dias. Os piores escores obtidos foram atribuídos ao Grupo G4 nos dois parâmetros de avaliação qualitativa. Diante dos resultados obtidos, observa-se que a romã (Punica granatum L.) possui ação cicatrizante na mucosa lingual de ratos Wistar. ABSTRACT The objective of this study was to observe the action of pomegranate (Punica granatum L.) on stomatitis induced burns on the dorso-lingual musosa in Wistar rats. Twenty-four male, adult Wister albino rats were used, from the bioterium of UNIVASF. There were four groups (G1: Pomegranate juice by gavage; G2: Pomegranate juice by gavage + local application of fruit peel tea; G3: Local application of fruit peel tea only and G4: a negative control). The burns were made with standard dental instruments. The treatments were performed twice a day for 14 days. Half the animals in each group (n = 3) were euthanized on the seventh day of experimentation, while the remainder were euthanized on day 14. The tongues were removed and fixed with a 10% formaldehyde buffer, processed as 5µm sections and stained with HE. Clinically the animals treated with tea showed better healing. For statistical analysis the Pearson chi-squared test was used. There was a statistical significance (p = 0.026 and p = 0.023) when compared to treatment with the degree of re-epithelialization and inflammation of the four groups studied. The G2 group showed complete healing within 14 days. The worst scores were found in the G4 group in both qualitative assessment parameters. Based on these results, it was observed that pomegranate (Punica granatum L.) has a healing action on the lingual mucosa of Wistar rats.

We investigated the transmission of 4 WDM channels at 40 Gb/s, through different optical links of approximate equal lengths, around 50 km, but with different residual dispersions produced by various types of fibers, G. 652 (STD) + DCF (dispersion compensating fiber), G. 653 (DS) and G. 655 (NZD+). The experimental setup includes components usually employed in laboratory characterizations of WDM transmission systems at 10 Gb/s. The optical system behavior is analyzed theoretically and experimentally with bit-error-rate (BER) measurements at 40 Gb/s, in the back to back configuration and transmitted trough different optical fiber links. The results show the generation of BER floor by spontaneous emission and phase-intensity noises, as well as by the chirp of the external modulator at the transmitter. Different approaches are discussed to upgrade the 10 Gb/s legacy, and to prevent the combination of chromatic dispersion effects, that produce severe penalties in WDM transmissions at 40 Gb/s.

Distributed gain and spectral gain-saturation effects of erbium-doped fiber amplifier (EDFA) were measured using a coherent reflectrometry technique. We find that the spectral performance can be improved if the gain needs are relaxed. A hole in the spectral dependence of the gain depletion was also observed, which could be related to the Spectral Hole Burning (SHB) phenomenon.

The distributed-gain along erbium doped fibres was measured with coherent optical frequency-domain reflectometry. The optimum length for different amplifier specifications were measured and compared to the cutback technique.