Author: "M.D. Cain" - Searchworks@Jio Institute Digital Library Search Results

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Author: G. Chieffi, D.H. Pemberton, J. Rivier, I.A. Cumming, Josephine Milner, K.B. Eik-Nes, M. Amoss, Marion Jackson, W.H. Rotsztejn, W.I.P. Mainwaring, S. Heller, Ghislaine Gallez, Christine Waelbroeck, J. Ghirlanda, G. Copinschi, R. Blackwell, G. Verhoeven, C. Kordon, R.S. Mical, S. Badawy, A.S. Goldman, R. Guillemin, J.-C. Heuson, A. Guitelman, R. Burgus, R. Johansson, L. Iela, M. Rajalakshmi, F.R. Mangan, W.A. Chamley, H.D. Schlumberger, R.E. Mancini, J.M. Brown, A. van den Ende, F. Neumann, J.C. Cerini, R.K. Rastogi, J.K. Findlay, A. Gillespie, F. Gogan, O.M. Cramer, G. Materazzi, R. Massa, H. Hassouna, P.R.K. Reddy, P. de Moor, rez Lloret, Denise E. Bu, Nicole Legros, C.C. Chang, M. Hery, K. Loewit, M. Monahan, Aliza Eshkol, Mildred E.D. Cerini, C. Robyn, R.S. Santti, J.R. Goding, M.D. Cain, L. Martini, W. Vale, K.A. Laurence, M.R.N. Prasad, R.G.A. van Wayjen, B. Scattolini, J.C. Porter, G. Grant, A. Jost, J.L. Pasteels, Shea, N. Ling, B. Lunenfeld, and Lupo di Prisco
Subjects: Reproductive Medicine, Obstetrics and Gynecology
Published: 1971

Author: Jack Hansky and M.D. Cain
Subjects: Blood Glucose, Male, medicine.medical_specialty, Anemia, Radioimmunoassay, digestive system, Antibodies, Secretin, Zollinger-Ellison Syndrome, Pernicious anaemia, Internal medicine, Anemia, Pernicious, Gastrins, Methods, medicine, Animals, Humans, Stomach Ulcer, Gastrin, medicine.diagnostic_test, biology, business.industry, digestive, oral, and skin physiology, General Medicine, Middle Aged, medicine.disease, Zollinger-Ellison syndrome, Endocrinology, Duodenal Ulcer, Immunoassay, biology.protein, Female, Rabbits, Antibody, business, hormones, hormone substitutes, and hormone antagonists
Abstract: Antibodies to human gastrin I have been produced in rabbits and formed the basis of a simple, precise, and specific immunoassay procedure for measuring gastrin concentration in human serum. Amounts as low as 5 pg. per ml. were detected, and fasting gastrin levels in subjects free of gastrointestinal disease ranged from 5 to 290 pg. per ml. with a mean of 113 pg. Patients with duodenal ulcer had a mean gastrin level of 53 pg. per ml., whereas gastric-ulcer patients had a value of 165 pg. per ml. High levels of up to 5000 pg. per ml. were found in patients with Zollinger-Ellison syndrome and pernicious anaemia. In several physiological studies on normal subjects, food and insulin hypoglycaemia were shown to stimulate gastrin secretion, and secretin produced a fall in serum-gastrin levels.
Published: 1969

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