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Digital twin is a revolutionizing technology. It involves sophisticated models such as real-time data, history data, simulation, machine learning, sensor updates which can reflect almost every detail of the physical objects, procedures, and services. Digital twin technology would be replicated the physical world into a virtual world in the future. Digital twin technology is considered state-of-the-art, but full implementation has yet to occur due to technical challenges and delays. The researchers have to create all the unique and specialized components of the thing or system and collect and combine a massive amount of diverse data. Since, many researchers and employees from some industries such as architecture, health care and engineering are still not completely understood about the technologies and tools used in digital twin technology. This paper illustrates scoping reviews of the characterization, implementation processes of digital twin in business information technology within 5 years period from 2018 to 2022. Furthermore, Digital Twin current applications in three different territories are also outlined in this paper. The purpose of the paper is to understand systematically about the digital twin technology process in different fields.

This research conducted by background of “X” Agency East Java Province as one of the biggest agencies with the highest number of employees in East Java and has a very broad work scope because it is a merged from some sub agencies before. Various social issues of East Java governance in 2015 became the main task of “X” Agency East Java Province to be completed. In order to fulfill their roles, responsibilities, and functions as the government agencies that serve people, all employees in “X” Agency East Java Province are required to be able to have optimal performance. This study aimed to analyze factors that can affect the performance of employees so can provide feedback to “X” Agency East Java Province in terms of corrective measures to be taken in the future in order to always have optimal performance. This study used partial least squares analysis through SmartPLS 3.0 program. Independent variables analyzed in this study were competence, motivation, leadership, and work environment towards dependent variable thus stress management and employee performance. Random sampling taken at 160 employees of “X” Agency East Java Province. Data collection process conducted by questionnaires distribution. The result showed that only competence and work environment has a significant effects on stress management, while stress management itself and competence also have a significant effects on employee performance. Other variables that is motivation and leadership does not have a significant effects on the dependent variable stress management and employee performance. Suggestion for improvement are given to the “X” Agency East Java Province at the end of the study in order to further improve their performance.

Means of rail transport in developing countries became major commodities integrated transportation solutions, rail transport is efficient for the number of mass transit. It opens the market potential procurement of railway facilities by PT INKA, both in the domestic market or abroad. As a make to order-based manufacturing started in 2008 with a lot of project exports to developing countries, such as Bangladesh, Malaysia and Singapore. PT INKA export market opportunities potentially enough ahead to 2020, but delays in delivery schedule of the train is the main problem is always the case in recent years. Methods of lean manufacturing focuses on identifying and eliminating activities that do not have added value, the first step was the elaboration of a method VSM (value stream mapping) as tools to determine mapping the entire process of production, then weighted 7 waste via a questionnaire and the results of the ranking of waste are translated through the method of RCA (root cause analysis) and then do an analysis matrix mapping tools with value stream analysis tools (VALSAT) and there is a value added value ratio of 60.17% of the 84 activities of production and the total cycle time 29,905 minutes. As a tool to mitigate the improvement of waste carried out the translation of failure mode and effect analysis (FMEA) and of design improvements value stream mapping - future state map can raise the value added ratio to 67.16% consists of 74 processes and production activities 26 795 minutes total cycle time. So this research can increase the productivity and know the activities that do not add value (Non Value Added) in line car body processes and eliminating waste (Waste) as one of the causes of train delays in delivery.

There are five telecommunications operators in Indonesia, including Telkomsel, Indosat Ooredoo, XL Axiata, Tri (3), and Smart Telecom compete to bring the latest 4G technologies as part of corporate strategy into the forefront of mobile communications services. PT XYZ is a multinational company engaged in the field of telecommunications services. The management of PT XYZ Surabaya targeting employee reporting can be increased up to 100%. This study aims to determine how much influence the intrinsic and extrinsic motivation on employee performance PT XYZ Surabaya with SEM-PLS method. The results of this study are extrinsic motivation variable that is most dominant supervision directly affects the performance of employees. Besides the variable performance of employees able to be explained by 0.655 or 65.5% by variable intrinsic motivation and extrinsic motivation, while 34.5% is explained by other variables.

PT PAL Indonesia is one of the largest company engaged in the maritime field, the existence of competition at national and international very tight then the company should always have a good strategy in the field of technology and human resources, so in this study focused on the performance of employees in the engineering division general. The study is aim to determine the effect of environment, facilities, incentives and motivation to employees performance in PT PAL Indonesia general engineering division. Using the technique of analysis Structural Equation Modelling (SEM) - Partial Least Square (PLS). The result of this study is performance variable explained by environmental, facilities, incentives and motivation only 64,4%, while 35,6% explained by other variables, significant effect on the environment of motivation with the value of t statistic 3,412, significant effect on environment of performance variable with the value of t statistic 1,97, and significant effect on motivation of performance variable with the value of t statistic 1,82.

Despite the importance of T 2 -weighted image in clinical practice, artifacts can significantly degrade image quality and affect diagnosis. This study quantitatively analyzed uterine displacement and surveyed the relationship between the image quality of fast-spin-echo-T 2 -weighted image of the female pelvis and quantitative value of uterine displacement. Overall, 147 women (mean age, 46.0 ± 12.8 years; age range, 22-84 years) who had undergone pelvic magnetic resonance imaging examination using a 3 T- magnetic resonance imaging scanner were included. Two radiologists performed a visual assessment of the fast-spin-echo-T 2 -weighted image in the sagittal plane in terms of ghosts and motion blur, and classified the image quality into the following three groups: poor, moderate, and excellent. Uterine displacement on half-Fourier acquisition single-shot turbo spin-echo-cine images was calculated, and the maximum amplitude of uterine displacement and summation of uterine displacement were calculated from the displacement map images. The Kruskal-Wallis and Steel-Dwass tests were performed to compare the maximum amplitude of uterine displacement and summation of uterine displacement among the three groups. Poor, moderate, and excellent image qualities were observed in 48, 71, and 28 patients, respectively. The quality of fast-spin-echo-T 2 -weighted images degraded statistically significantly with P < 0.01 as the maximum amplitude of uterine displacement increased. The summation of uterine displacement in the poor and moderate groups had greater statistical significance with P < 0.01 than that in the excellent group., Competing Interests: Declarations. Conflicts of interest: The authors have no potential conflicts of interest to declare. Ethics approval: This was a cross-sectional retrospective study. The study protocol was approved by the Institutional Ethics Committee (file number: REC2023-067). Considering data anonymization and retrospective study design, the requirement for written informed consent was waived. All procedures involving human participants adhered to the ethical standards of the institutional and/or national research committee and the 1964 Helsinki Declaration and its subsequent amendments or comparable ethical standards., (© 2024. The Author(s), under exclusive licence to Japanese Society of Radiological Technology and Japan Society of Medical Physics.)

The side effects of kwao keur dietary supplements (obtained from the tuberous root of Pueraria mirifica) have recently been reported by the Ministry of Health, Labour and Welfare, Japan. To control the quality of kwao keur products, its ingredients need to be maintained by characteristic marker compounds, such as miroestrol, deoxymiroestrol, and kwakhurin (KWA). In this study, we described the facile synthesis of KWA, a marker compound of P. mirifica. Our revised synthetic method produced KWA with shorter steps and higher yield than the reported method. Furthermore, the absolute purity of KWA was determined by quantitative NMR analysis for standardization as a reagent, and its purity was 92.62 ± 0.12%.

Under the irradiation of red light (690 nm), quinones were converted to hydroquinones by thiols in the presence of metallophthalocyanines. The reaction proceeded via the charge separation between the triplet state of phthalocyanine and the quinone. The product determining step was protonation of the quinone anion radical, as indicated by the fact that the reaction was accelerated by the use of more acidic thiols or addition of an acid.

2SS[6-127,64-80] variant of lysozyme which has two disulfide bridges, Cys6-Cys127 and Cys64-Cys80, and lacks the other two disulfide bridges, Cys30-Cys115 and Cys76-Cys94, was quite unstructured in water, but a part of the polypeptide chain was gradually frozen into a native-like conformation with increasing glycerol concentration. It was monitored from the protection factors of amide hydrogens against H/D exchange. In solution containing various concentrations of glycerol, H/D exchange reactions were carried out at pH* 3.0 and 4 degrees C. Then, (1)H-(15)N-HSQC spectra of partially deuterated protein were measured in a quenching buffer for H/D exchange (95% DMSO/5% D(2)O mixture at pH* 5.5 adjusted with dichloroacetate). In a solution of 10% glycerol, the protection factors were nearly equal to 10 at most of residues. With increasing glycerol concentration, some selected regions were further protected, and their protection factors reached about a 1000 in 30% glycerol solution. The highly protected residues were included in A-, B-, and C-helices and beta3-strand, and especially centered on Ile 55 and Leu 56. In 2SS[6-127,64-80], long-range interactions were recovered due to the preferential hydration by glycerol in the hydrophobic box of the alpha-domain. Glycerol-induced recovering of the native-like structure is discussed from the viewpoint of molten globules growing with the protein folding. (c) 2009 Wiley Periodicals, Inc. Biopolymers 91: 665-675, 2009.This article was originally published online as an accepted preprint. The "Published Online" date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com.

At this sanatorium, the number of foot bottom ulcer patients was 13 and the tenure of the foot bottom ulcer was average 11 years. According to the treatment that was not unified, we thought about the cause of the prolongation. Therefore, we made evaluation and care method sheet ("foot care sheet") of the ulcer for the unification. We used the foot pressure measurement system (F-scan) to 4 patients for the pressure dispersion of the ulcer. We devised the protection law of the ulcer, and an ulcer did not require pressure more than 5 kilos/cm2. We recorded the size of the ulcer, weight of the liquid from ulcer, a photograph to care sheet once a week. I performed ulcer protection law and management with the foot care sheet to 4 patients for average 4 months. As a result, the ulcers of 3 patients out of 4 patients became small.

This is the report of phase III study to evaluate the safety and utility of 111In-DTPA-IgG in patients with strongly suspected inflammation/infection. One hundred and forty five patients with suspected sites of inflammation/infection were enrolled in the study. Only a few adverse experiences in one patient were reported, which were interpreted as having a possible relationship to the agent. A total of 171 suspected sites (12 in head and neck, 39 in thorax, 44 in abdomen and pelvis, 62 in musculoskeletal system, and 14 in other regions) were evaluated by investigators at each institute. Out of 171 sites, 18 were determined to be unevaluable, and 12 false negative and 5 false positive cases were observed. Overall sensitivity and specificity was 89.8% and 85.7%, respectively, and the agent proved to be effective in detecting lesions anywhere throughout the body. The analysis of data from this Phase III study indicates that 111In-DTPA-IgG is well-tolerated in patients and effective in determining focal sites of inflammation/infection although the physiological accumulation in some tissues such as the sinus or liver and possible excretion into the gastrointestinal tract may make it difficult to localize lesions.

Recently it has become clear that venous impotents account for a high percentage of all impotents. In venous impotents a decrease in outflow resistance is seen. We have aggressively performed operations on venous impotents to produce artificial outflow resistance. In this study, we performed ligations of the crura penis in 6 venous impotents. Five patients recovered from erectile dysfunction and 1 patient showed papaverine-induced full erection. There were few severe complications and the duration of operation was very short. This operation is thought to be a simple and effective treatment for venous impotence.