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1. Registration of ‘NW13493’ hard white winter wheat

Author

P. S. Baenziger, K. A. Frels, J. Boehm, V. Belamkar, D. J. Rose, L. Xu, S. M. Finnie, S. N. Wegulo, T. Regassa, A. C. Easterly, C. F. Creech, D. K. Santra, R. N. Klein, Y. Jin, J. Kolmer, M.‐S. Chen, R. L. Bowden, M. J. Guttieri, G. Bai, I. El‐Basyoni Salah, S. D. Masterson, and J. Poland

Subjects
Genetics, Agronomy and Crop Science
Published
2022
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2. Registration of LCS ‘Valiant’ hard red winter wheat

Author

P. S. Baenziger, S. D. Masterson, J. D. Boehm, V. Belamkar, M. D. Barnett, D. J. Rose, L. Xu, S. N. Wegulo, T. Regassa, A. C. Easterly, C. F. Creech, D. K. Santra, G. R. Kruger, G. W. Hergert, R. N. Klein, Y. Jin, J. Kolmer, M.‐S. Chen, G. L. Hein, R. L. Bowden, M. J. Guttieri, G. Bai, I. El‐Basyoni Salah, and J. Poland

Subjects
Genetics, Agronomy and Crop Science
Published
2022
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3. Registration of ‘Epoch’ hard red winter wheat

Author

P. S. Baenziger, K. A. Frels, J. Boehm, V. Belamkar, D. J. Rose, L. Xu, S. N. Wegulo, T. Regassa, A. C. Easterly, C. F. Creech, D. K. Santra, R. N. Klein, Y. Jin, J. Kolmer, M.‐S. Chen, M. J. Guttieri, G. Bai, I. El‐Basyoni Salah, S. D. Masterson, and J. Poland

Subjects
Genetics, Agronomy and Crop Science
Published
2022
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4. Methicillin resistance gene diversity in staphylococci isolated from captive and free-ranging wallabies

Author

Michelle M. S. Chen, Wayne S. J. Boardman, and Melissa H. Brown

Subjects
macropods, wildlife, Staphylococcus, methicillin-resistance, SCCmec, Infectious and parasitic diseases, RC109-216
Abstract

Background: Infection with methicillin-resistant staphylococci (MRS) can be life-threatening in humans and its presence in animals is a cause for public health concern. The aim of this study was to measure the prevalence of MRS in captive and free-ranging wallabies over a 16-month period in South Australia, Australia. Materials and methods: Eighty-nine purified staphylococcal isolates recovered from 98 captive and free-ranging wallabies' anterior nasal swabs were used in this study. All isolates were tested for the presence of the mecA, mecA1, and mecC genes. Multiplex PCR-directed SCCmec-typing, ccrB-typing, and determination of the minimal inhibitory concentration of oxacillin were performed on mec-positive isolates. Results and discussion: In total, 11 non-Staphylococcus aureus MRS were isolated from 7 out of 98 animals, corresponding to a 7.1% carriage rate. The SCCmec types I, III, and V were identified by multiplex PCR and sequencing of the ccrB gene. This is the first report of MRS carriage in both captive and free-ranging wallabies in Australia. These data demonstrate a low prevalence of MRS and no association between wallaby captivity status and MRS carriage could be assigned. These animals may act as a reservoir for the exchange of genetic elements between staphylococci. Furthermore, the mecA genes of animal isolates were identical to that found in human MRS strains and thus the possibility of zoonotic transfer must be considered.

Published
2016
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7. Two Zn(II)/Cu(II) complexes based on flexible mixed ligands: syntheses, structural characterization, and luminescence sensing of nitrobenzene

Author

W. Li, M.-S. Chen, W.-W. Fu, Y.-Q. Yang, and Y. Liu

Subjects
Inorganic Chemistry, Nitrobenzene, chemistry.chemical_compound, chemistry, Polymer chemistry, Materials Chemistry, Physical and Theoretical Chemistry, Luminescence, Characterization (materials science)
Abstract

Two Zn(II) and Cu(II) complexes formulated as Zn(DMS)(bix)0.5 (1) and Cu(DMS)(bix)0.5 (2) (DMS = 2,2-dimethylsuccinate; bix = 1,4-bis(imidazol-1-ylmethyl)benzene) are successfully prepared under hydrothermal conditions. The single crystal X-ray diffraction (XRD) analysis shows that both complexes are isostructural, have the P2/c space group and a 2D layer architecture with the DMS bisbridged ribbon. The title complexes are characterized by single crystal XRD, IR spectroscopy, TG and elemental analyses, and photoluminescence sensing in the solid state. In addition, the sensing efficiency of nitrobenzene for 1 is evaluated.

Published
2021
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9. [Thinking and suggestion on the definition, classification and Chinese nomenclature of carcinoma of the bile ducts]

Author

M S, Chen

Subjects
Cholangiocarcinoma, China, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Humans, Bile Ducts, Prognosis, Neoplasm Staging
Abstract

At present, the classification, nomenclature, and definition of carcinoma of the bile ducts are controversial. Moreover, there is no uniformity between China and aboard, which has brought confusion to clinical practice. It needs to clarify regarding tumor naming principles, anatomical location, tumor origin, pathological classification, biological characteristics, clinical manifestations, treatment methods, etc. Additionally, the WHO tumor classification, UICC staging, ICD disease classification, relevant Chinese regulations, EASL, AJCC staging, and NCCN guidelines were also needed to be referred. After investigating the above-mentioned latest authoritative literature, based on the existing problems, combined with clinical practice in China, the author reevaluated the definition, classification, and nomenclature of cholangiocarcinoma, and proposes updated suggestions. Hoping to standardize and unify clinical practice for classification and nomenclature of cholangiocarcinoma in China.目前关于胆管癌的分类、命名和定义在国内外均存在较多争议，给临床工作的使用带来了混乱。此工作需要根据肿瘤命名原则、解剖部位、肿瘤起源、病理分类、生物学特征、临床表现、治疗方式等；还需要遵循：WHO肿瘤分类、UICC分期、ICD疾病分类、中国相关规范；并参考欧洲肝病学会指南、AJCC分期、NCCN指南。作者针对所存在的问题，结合我国临床实际，对胆管癌的定义、分类和中文命名进行思考，并提出更新建议，希望能够规范和统一临床实际工作中胆管癌的分类和中文命名。.

Published
2022

10. [Suggestions on the nomenclature of liver cancer]

Author

M S, Chen, L, Xu, Y J, Zhang, Z G, Zhou, R P, Guo, and Y F, Yuan

Subjects
Cholangiocarcinoma, Bile Ducts, Intrahepatic, Carcinoma, Hepatocellular, Bile Duct Neoplasms, Liver Neoplasms, Humans
Abstract

Currently, the systematized nomenclature of medicine (SNOMED) of liver cancer is confusing, and it is mixed with the SNOMED of cholangiocarcinoma. We hereby presented our own points, hoping to provide a reference for standardizing the nomenclatures and classifications of liver cancer in future clinical studies. The preface of Chinese Guidelines of Primary Liver Cancer Diagnosis and Treatment (2019 Edition) indicated that primary liver cancer mainly includes three different pathological types, hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC), and mixed-type carcinoma of both HCC and ICC. These three types of carcinoma show great differences in terms of pathogenesis, biological behavior, histological morphology, treatment methods, and prognosis, among which, HCC accounts for 85% to 90%. Therefore, this study is a detailed analysis of the above-mentioned related SNOMED and proposes suggestions for corrections.目前肝癌的命名很不规范，并与胆管癌命名混淆，作者在此提出自己的观点，希望能够为规范今后肝癌的命名与分类提供参考。我国“原发性肝癌诊疗规范（2019年版）”（以下简称“规范”）的前言部分指出：原发性肝癌主要包括肝细胞癌（HCC）、肝内胆管癌（ICC）和HCC-ICC混合型3种不同病理学类型，3者在发病机制、生物学行为、组织学形态、治疗方法以及预后等方面差异较大，其中HCC占85%~90%。本文就上述相关名称作详细分析并提出更正建议。.

Published
2021

14. Decrease in the effectiveness of valproic acid against the background of antibacterial therapy with imipenem/cilastatin in pediatric practice: A case report

Author

A. B. Strok, M. S. Chenkurov, M. N. Kostyleva, and D. A. Umutkuzina

Subjects
antiepileptic therapy, valproates, drug interaction, therapeutic drug monitoring, combination therapy, epilepsy, seizures, Medicine
Abstract

A clinical case of the co-medication of valproic acid and cilastatin/imipenem in a 17-year-old girl with generalized tonic-clonic seizures is described. As an antiepileptic therapy, the child was prescribed valproic acid, the concentration of which in the blood plasma was more than 80 µg/ml, and seizures were not observed during this therapy. At the same time, due to the developed pneumonia, the girl was imipenem/cilastatin prescribed. Co-medication of drugs led to a decrease in the concentration of valproic acid in the blood plasma less than 50 µg/ ml, relapse of epileptic seizures was noted. Correction of antiepileptic therapy with phenobarbital did not lead to the seizure control. The removal of imipenem/ cilastatin contributed to the increase in the concentration of valproic acid in blood plasma above 50 µg/ ml, which corresponds to the recommended therapeutic range. Within two weeks after discontinuation of imipenem/ cilastatin, the concentration of valproic acid reached values as close as possible to the values before the start of antibiotic therapy. The authors of the article concluded that it is necessary to conduct therapeutic drug monitoring in children receiving valproic acid and imipenem/ cilastatin (antibiotic of carbapenem group), based on the known mechanisms of pharmacokinetic interaction.

Published
2024
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16. Uranium speciation and in situ leaching of a sandstone-type deposit from China

Author

P. Liu, M. S. Chen, Xianke Lin, Z. G. Li, Q. Ma, and Zhiyuan Feng

Subjects
In situ leach, Health, Toxicology and Mutagenesis, Metallurgy, Public Health, Environmental and Occupational Health, chemistry.chemical_element, Sulfuric acid, Uranium, 010502 geochemistry & geophysics, 010403 inorganic & nuclear chemistry, Leaching rate, 01 natural sciences, Pollution, 0104 chemical sciences, Analytical Chemistry, chemistry.chemical_compound, Uranium ore, Nuclear Energy and Engineering, chemistry, Environmental science, Radiology, Nuclear Medicine and imaging, Leaching (metallurgy), Spectroscopy, 0105 earth and related environmental sciences
Abstract

In this paper, uranium ore samples collected from different hole depth and different numbered hole. The effects of uranium speciation to in situ leaching of uranium were analyzed by sequential chemical extraction and sulfuric acid leaching tests. These results imply that the distribution characteristics of uranium speciation are significantly different whether they are in the same numbered uranium ore sample or in the different numbered uranium ore samples. The residual uranium are the most component in primary mineral. The acidity has a great influence on the leaching rate of uranium ore in situ leaching of uranium.

Published
2016
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17. Correction: Pomalidomide, bortezomib, and low-dose dexamethasone in lenalidomide-refractory and proteasome inhibitor-exposed myeloma

Author

P. G. Richardson, C. C. Hofmeister, N. S. Raje, D. S. Siegel, S. Lonial, J. Laubach, Y. A. Efebera, D. H. Vesole, A. K. Nooka, J. Rosenblatt, D. Doss, M. H. Zaki, A. Bensmaine, J. Herring, Y. Li, L. Watkins, M. S. Chen, and K. C. Anderson

Subjects
Cancer Research, Oncology, hemic and lymphatic diseases, Original Article, Hematology, neoplasms
Abstract

This phase 1 dose-escalation study evaluated pomalidomide, bortezomib (subcutaneous (SC) or intravenous (IV)) and low-dose dexamethasone (LoDEX) in lenalidomide-refractory and proteasome inhibitor-exposed relapsed or relapsed and refractory multiple myeloma (RRMM). In 21-day cycles, patients received pomalidomide (1–4 mg days 1–14), bortezomib (1–1.3 mg/m2 days 1, 4, 8 and 11 for cycles 1–8; days 1 and 8 for cycle ⩾9) and LoDEX. Primary endpoint was to determine the maximum tolerated dose (MTD). Thirty-four patients enrolled: 12 during escalation, 10 in the MTD IV bortezomib cohort and 12 in the MTD SC bortezomib cohort. Patients received a median of 2 prior lines of therapy; 97% bortezomib exposed. With no dose-limiting toxicities, MTD was defined as the maximum planned dose: pomalidomide 4 mg, bortezomib 1.3 mg/m2 and LoDEX. All patients discontinued treatment by data cutoff (2 April 2015). The most common grade 3/4 treatment-emergent adverse events were neutropenia (44%) and thrombocytopenia (26%), which occurred more frequently with IV than SC bortezomib. No grade 3/4 peripheral neuropathy or deep vein thrombosis was reported. Overall response rate was 65%. Median duration of response was 7.4 months. Pomalidomide, bortezomib and LoDEX was well tolerated and effective in lenalidomide-refractory and bortezomib-exposed patients with RRMM.

Published
2018

18. L-butyl phthalein improves neural function of vascular dementia mice by regulating the PI3K/AKT signaling pathway

Author

D-P, Chen, S-H, Hou, Y-G, Chen, M-S, Chen, Z-Z, Hu, and Z-J, Zhang

Subjects
Male, Dementia, Vascular, Apoptosis, Hippocampus, Mice, Inbred C57BL, Mice, Reperfusion Injury, Animals, Phosphatidylinositol 3-Kinase, Phosphorylation, Reactive Oxygen Species, Proto-Oncogene Proteins c-akt, Benzofurans, Signal Transduction
Abstract

L-3-n-butylphthalide (L-NBP) is a type of anti-ischemic cranial nerve protective drug that may act on vascular dementia (VD). Phosphatidylinositol-3 kinase (PI3K)/protein kinase B (AKT/PKB) signaling pathway can up-regulate B-cell lymphoma 2 (Bcl-2) expression, reduce reactive oxygen species (ROS) production, and alleviate cell apoptosis. This study aimed at investigating the role of L-NBP on neurological function and cell apoptosis in VD mouse through regulating PI3K/AKT signaling pathway.The mice were divided into four groups, including Sham, VD, VD + solvent, and VD + L-NBP. HT22 cells were cultured in vitro and treated by ischemia/reperfusion (I/R). HT22 cells were divided into four groups, including I/R, VD + solvent, VD + L-NBP, and VD + L-NBP + LY294002 groups. Phosphorylated AKT (p-AKT) and Bcl-2 expressions were tested. ROS content in hippocampus tissue was detected by flow cytometry. Cell apoptosis was evaluated by transferase-mediated deoxyuridine triphosphate-biotin nick end labeling (TUNEL) assay.ROS content and cell apoptosis increased, while p-AKT and Bcl-2 expressions reduced in hippocampus tissue from VD group compared with sham group. L-NBP significantly up-regulated p-AKT and Bcl-2 expressions and decreased ROS content and cell apoptosis in hippocampus tissue. I/R treatment markedly induced HT22 cell apoptosis and ROS production, and reduced p-AKT and Bcl-2 expressions. L-NBP treatment markedly up-regulated p-AKT and Bcl-2 levels, restrained cell apoptosis, and reduced ROS content in TH22 cells intervened by I/R. LY294002 apparently attenuated the protective effect of L-NBP on HT22 cells.L-NBP protects VD by up-regulating PI3K/AKT signaling pathway, elevating Bcl-2 expression, reducing nerve cell apoptosis, and restraining ROS production.

Published
2018

22. [Multidisciplinary therapeutic strategies for recurrence and metastasis of liver cancer]

Author

J C, Chen and M S, Chen

Subjects
Liver Neoplasms, Humans, Neoplasm Metastasis, Neoplasm Recurrence, Local
Abstract

With the development of early diagnostic and surgical techniques, the postoperative outcome of patients with liver cancer is gradually improved, but long-term outcome remains unsatisfactory. The therapeutic methods for recurrent tumors include multidisciplinary therapeutic methods such as reoperation, local treatment, and systematic treatment. Multidisciplinary therapies can improve the overall response of recurrent liver cancer, and it can combine various therapies from different disciplines according to the patient's condition and take advantages of each therapy in order to achieve the best therapeutic effect.

Published
2016

23. Preclinical study on induction of pluripotent stem cells from urine of dilated cardiomyopathy patients

Author

Y-H, Lin, X-M, Chen, J-W, Zhang, X-Q, He, W-J, Dai, and M-S, Chen

Subjects
Cardiomyopathy, Dilated, Pluripotent Stem Cells, Kruppel-Like Factor 4, SOXB1 Transcription Factors, Induced Pluripotent Stem Cells, Humans, Cell Differentiation, Urine
Abstract

Dilated cardiomyopathy (DCM) is featured by left or bilateral ventricular dilation combined with systolic dysfunction. Its clinical manifestations include heart enlargement, cardiac failure, arrhythmia and cardiac arrest. Medication and heart transplantation have but only limited treatment effect on DCM.Induced pluripotent stem cell (iPSC) treatment provides a new solution for DCM treatment. Human renal epithelial cells were extracted from the urine of patients with DCM and transfected with Sendai virus carrying OCT3/4, Sox2, Klf4 and c-Myc gene to generate iPSCs by reprogramming.The morphology and pluripotency of iPSCs obtained from the renal epithelial cells from patients with DCM were confirmed, as well as the growth characteristics, immunohistochemical features and surface markers of embryonic stem cells. Teratoma was formed in vivo.We demonstrated that it was feasible to obtain iPSCs from the urine of patients with DCM. This technique lays down the cytological foundation for understanding the pathogenesis and for drug screening and gene therapy for DCM.

Published
2016

24. Fusarium proliferatum: A New Pathogen Causing Fruit Rot of Peach in Ningde, China

Author

Chong Zhang, Y. B. Jiang, S. H. Xie, Y. Q. Zheng, Z. P. Wei, X. Lin, and M. S. Chen

Subjects
0106 biological sciences, Fusarium, biology, Inoculation, food and beverages, Fusarium proliferatum, Plant Science, biology.organism_classification, 01 natural sciences, Conidium, Crop, 010602 entomology, Prunus, Horticulture, Potato dextrose agar, Agronomy and Crop Science, Mycelium, 010606 plant biology & botany
Abstract

Peach (Prunus persica L.) is an economically important tree fruit crop worldwide. China’s planting area and yield of peaches are the first in the world (Verde et al. 2013). During June to July 2017, losses of at least 20% associated with fruit rot of peaches (cv. Zhongtao No. 5) were observed in several commercial orchards of Ningde, Fujian Province (26.67°N, 119.52°E). Affected fruit showed water-soaked areas on the skin and extensive internal decay, with white mycelium on the surface of decayed areas. Fifteen diseased fruit were collected from three different orchards. Diseased fruit tissues were cut into 5-mm pieces, surface disinfested with 1% sodium hypochlorite for 1.5 min, and placed on 1.5% potato dextrose agar (PDA) amended with 0.02% streptomycin sulfate. A total of 12 pure cultures were collected by single-spore isolations. The isolates produced abundant, white, aerial mycelium and violet-to-dark (with age) pigments in the PDA. Based on observations of 1-week-old isolates, macroconidia were 2 to 5 septate and 21.4 to 46.8 × 2.7 to 4.5 μm in size, average 34.6 × 3.6 μm (n = 25), and microconidia were 6.0 to 13.3 × 2.2 to 4.6 μm in size, average 8.5 × 3.4 μm (n = 25). These morphological characteristics were consistent with previous descriptions of Fusarium (Mun et al. 2012; Summerell et al. 2003); therefore, we preliminarily identified the cultures as Fusarium spp. Genomic DNA was extracted from single conidial cultures of three representative isolates. The isolates were further identified by polymerase chain reaction (PCR) sequencing using two different primer sets: ITS1/ITS4 and EF1/EF2. Primers ITS1/ITS4 (White et al. 1990) resulted in a 508-bp amplicon (GenBank accession no. MF963046). The BLASTn analysis showed a 100% sequence identity with F. proliferatum (KU527804). Primers EF1/EF2 amplified translation elongation factor (TEF) (Geiser et al. 2004), and the resulting TEF sequence (MF963047) was 99% similar to that of F. proliferatum (AB674284). Pathogenicity was confirmed by inoculating 12 surface-sterilized peach fruit with a conidial suspension (1 × 10⁶ conidia/ml). The peaches were stab inoculated to a depth of 1 mm using a sterile needle. Controls were inoculated with sterile distilled water. The peaches were wrapped in plastic bags and stored in a growth chamber at 25°C, 90% relative humidity, and a daily 12-h photoperiod. After 5 days, symptoms of soft rot similar to those in the commercial fields were observed from all inoculated peaches. Controls displayed no symptoms. The pathogen was reisolated from the diseased fruit but not from the controls, and it was confirmed to be F. proliferatum by microscopy and PCR sequencing. To our knowledge, this is the first report of F. proliferatum causing rot disease on peach in China. Considering the economic importance of peach in China and throughout the world, further study of fruit decay of peach caused by F. proliferatum is warranted.

Published
2018
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25. Comparison of gel-forming properties of silver carp (Hypophthalmichthys molitrix) surimi prepared in different seasons

Author

C. Yuan; Fukuda, Y., Kaneniwa, M.; S. Chen, Y. Cheng, X. Wang, and Konno, K.

Subjects
Gelation -- Research, Carp -- Research, Surimi -- Research, Business, Food/cooking/nutrition
Abstract

The gel-forming properties of silver carp surimi prepared in different seasons are compared. It was found that surimi prepared in winter and spring formed gel at 30 degree Celsius, while autumn and summer surimi required a higher temperature of 40 degree Celsius for gel formation.

Published
2005

26. Clonal diversity of methicillin-sensitive

Author

Michelle M S, Chen, Stefan, Monecke, and Melissa H, Brown

Subjects
Healthy wildlife, Short Communication, StaphyType, DNA microarray, MSSA, Macropods
Abstract

Seven methicillin-sensitive Staphylococcus aureus nasal isolates from apparently healthy captive and wild wallabies were characterised by DNA microarray and antibiotic susceptibility assays. Isolates were found to belong to uncommon clonal complexes including those previously associated with birds, pigs and humans., Highlights • First study of commensal staphylococci in apparently healthy Australian macropods. • Resistance and virulence genes were rare in these MSSA isolates. • Recent transmission of MSSA-CC15 from humans to wallabies. • “Australian” S. aureus clones ST93 and ST1850 were not recovered.

Published
2015

28. Normalised quadratic controls for a class of bilinear systems

Author

Y.-Z. Chen and M.-S. Chen

Subjects
Mathematical analysis, Optimal control, Controllability, Definite quadratic form, Quadratic equation, Exponential stability, Exponential growth, Control and Systems Engineering, Control theory, Electrical and Electronic Engineering, Exponential decay, Instrumentation, Eigenvalues and eigenvectors, Mathematics
Abstract

Normalised quadratic control, a modification of the conventional quadratic control method, has recently been proposed to exponentially stabilise a homogeneous bilinear system whose open-loop eigenvalues all fall on the imaginary axis. The normalised quadratic control method is now extended to a broader class of bilinear systems whose open-loop eigenvalues may fall to the left or right of the imaginary axis. It is shown that for bilinear systems that are already open-loop stable, the normalised quadratic control can add to the system an extra exponential decay rate. For open-loop unstable bilinear systems, the normalised quadratic control can stabilise the system if the extra exponential decay rate provided by the control is larger than the open-loop system's growth rate.

Published
2002
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29. Performance Improvement of a Virtual-Ground Nonvolatile Charge-Trap Storage nor-Type Memory Cell With Optimized Junction Dosage for 45-nm Generation Node

Author

W.P. Lu, M. S. Chen, S W Huang, G D Lee, S.H. Ku, Chih-Yuan Lu, C H Tsai, N K Zous, W C Tzeng, Kuang-Chao Chen, K W Liu, T.F. Ou, and C H Liu

Subjects
Materials science, business.industry, Electrical engineering, Charge density, Integrated circuit, Flash memory, Electronic, Optical and Magnetic Materials, law.invention, Non-volatile memory, Impact ionization, law, Virtual ground, Logic gate, Optoelectronics, Electrical and Electronic Engineering, business, Leakage (electronics)
Abstract

A variety of cell performances, such as program speed, second-bit effect, program disturbance along the channel direction (X-disturbance), and random telegraph noise (RTN), are investigated extensively under different junction dosages in a virtual-ground charge-trap nor array of 45-nm technology. Junction profiles and the location of programmed charges are compared by means of a gate-induced drain leakage scheme. Experiments reveal that the source/drain dosage beneath gate edges affects the program speed, injected charge distribution, X-disturbance induced by secondary impact ionization, and RTN performance.

Published
2011
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30. Stress effect on Raman spectra of Ce-doped BaTiO3films

Author

Zhongjun Chen, Wensheng Shi, Dafu Cui, Zexiang Shen, M S Chen, and Sing Hai Tang

Subjects
Materials science, Annealing (metallurgy), business.industry, Analytical chemistry, Condensed Matter Physics, Grain size, Pulsed laser deposition, symbols.namesake, Lattice constant, Optics, symbols, General Materials Science, Thin film, Raman spectroscopy, Spectroscopy, business, Single crystal
Abstract

Ce-doped BaTiO3 (BTO:Ce) thin films prepared on MgO (100) substrates by pulsed laser deposition (PLD) at oxygen pressure of 1.2×10-3 and 17 Pa have been studied by micro-Raman spectroscopy, x-ray diffraction (XRD) and atomic force microscopy (AFM). The film deposited at lower oxygen pressure has a larger lattice parameter in the direction normal to the substrate surface, and the film has smaller grains and a smoother surface. The polarized Raman peaks of both as-deposited films show blue shifts and linewidth broadening in comparison to those of the BaTiO3 single crystal. The blue shifts are attributed to tensile stresses in the films. Our results indicate that the grain size increases and the tensile stress relaxes with annealing. We have shown that quantum confinement and oxygen vacancies are not the dominant factors for the observed Raman spectral changes.

Published
2000
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31. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

Author

Franziska Christ, Martin E. Schwab, M S Chen, Lisa Schnell, Adrian Spillmann, A B Huber, Martin Frank, and M E van der Haar

Subjects
Nogo Proteins, Multidisciplinary, Neurite, Nogo Receptor 1, Central nervous system, Biology, Cell biology, Oligodendrocyte-Myelin Glycoprotein, Myelin, medicine.anatomical_structure, Dorsal root ganglion, mental disorders, Immunology, medicine, psychological phenomena and processes, Reticulon 4
Abstract

The capacity of the adult brain and spinal cord to repair lesions by axonal regeneration or compensatory fibre growth is extremely limited. A monoclonal antibody (IN-1) raised against NI-220/250, a myelin protein that is a potent inhibitor of neurite growth, promoted axonal regeneration and compensatory plasticity following lesions of the central nervous system (CNS) in adult rats. Here we report the cloning of nogo A, the rat complementary DNA encoding NI-220/250. The nogo gene encodes at least three major protein products (Nogo-A, -B and -C). Recombinant Nogo-A is recognized by monoclonal antibody IN-1, and it inhibits neurite outgrowth from dorsal root ganglia and spreading of 3T3 fibroblasts in an IN-1-sensitive manner. Antibodies against Nogo-A stain CNS myelin and oligodendrocytes and allow dorsal root ganglion neurites to grow on CNS myelin and into optic nerve explants. These data show that Nogo-A is a potent inhibitor of neurite growth and an IN-1 antigen produced by oligodendrocytes, and may allow the generation of new reagents to enhance CNS regeneration and plasticity.

Published
2000
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32. Very short-term load forecasting using artificial neural networks

Author

M.-S. Chen and W. Charytoniuk

Subjects
Engineering, Training set, Artificial neural network, business.industry, Load forecasting, Training (meteorology), Energy Engineering and Power Technology, Machine learning, computer.software_genre, Reliability engineering, Term (time), Task (project management), Set (abstract data type), Operator (computer programming), Artificial intelligence, Electrical and Electronic Engineering, business, computer
Abstract

In a deregulated, competitive power market, utilities tend to maintain their generation reserve close to the minimum required by an independent system operator. This creates a need for an accurate instantaneous-load forecast for the next several dozen minutes. This paper presents a novel approach to very short-time load forecasting by the application of artificial neural networks to model load dynamics. The proposed algorithm is more robust as compared to the traditional approach when actual loads are forecasted and used as input variables. It provides more reliable forecasts, especially when the weather conditions are different from those represented in the training data. The proposed method has been successfully implemented and used for online load forecasting in a power utility in the United States. To assure robust performance and training times acceptable for online use, the forecasting system was implemented as a set of parsimoniously designed neural networks. Each network was assigned a task of forecasting load for a particular time lead and for a certain period of day with a unique pattern in load dynamics. Some details of this are presented in the paper.

Published
2000
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33. Nonlinear rivulet dynamics during unstable wetting flows

Author

George M. Homsy, David T Moyle, and M.-S Chen

Subjects
Fluid Flow and Transfer Processes, Physics, business.industry, Capillary action, Mechanical Engineering, General Physics and Astronomy, Mechanics, Slip (materials science), Lubrication theory, Capillary number, Physics::Fluid Dynamics, Viscous fingering, Contact angle, Nonlinear system, Optics, business, Dimensionless quantity
Abstract

The growth and propagation of nonlinear rivulets is studied. Lubrication theory and a Navier type slip model are used to establish the thin film equation for the nonlinear evolution of the height of liquid in the vicinity of a driven contact line. This equation is then solved using a semi-implicit numerical scheme, adapted to handle the moving boundary nature of the problem. The problem involves two parameters, α, a dimensionless slip parameter and the dimensionless contact slope C= 3Ca −1/3 tan θ , where θ is the contact angle and Ca is the capillary number, μU/σ. A parametric study establishes both the shapes and the dynamics of nonlinear rivulet propagation. The shapes are found to be relatively independent of the slip parameter and are primarily determined by the contact slope, while the rivulet speeds are dependent on the level of slip, as expected. The computed shapes, including the occurrence of a capillary bulge near the advancing front, are in excellent agreement with experiments. Chevron-shaped steady traveling wave solutions, and both chevron and straight-sided convectively propagating shapes are obtained, with the traveling wave solutions occurring for small contact slope and the straightsided solutions for large slope. Complete coating of the substrate in the presence of rivulet instabilities occurs only for C>1.0. The predictions are in excellent agreement with experiments and suggest that simple lubrication theory and slip models are all that is necessary to describe the observed shapes and dynamics.

Published
1999
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34. Pharmacokinetic analysis of meropenem therapeutic drug monitoring data (TDM) in critically ill adult patients

Author

I. B. Bondareva, S. K. Zyryanov, and M. S. Chenkurov

Subjects
meropenem, pharmacokinetic/pharmacodynamic modeling, therapeutic drug monitoring, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Meropenem is a carbapenem antibiotic widely used in treatment of severe infections in ICU. Critically ill patients’ pathophysiological features may cause changes in the pharmacokinetics of meropenem, such as augmented/impaired renal clearance, as well as an increase in the volume of distribution of the drug. Considerable variability in meropenem concentration for the same dosage regimen, severity of the diseases and the escalating antibiotic resistance support the need for an individualization of the dosing in critically ill patients. Estimation of meropenem pharmacokinetic (PK) parameters was performed using the NPAG (non-parametric adaptive grid) program from the Pmetrics package based on peak-trough TDM data. A one-compartment linear PK model with zero-order input and first-order elimination was used to analyze data of the 36 critically ill patients (66 measured meropenem concentrations totally) and to predict pharmacodynamic (PD) parameter values (%T>MIC) based on the time course of free meropenem concentration for empirically prescribed dosage regimens by MIC level. The estimated PK parameters of the meropenem model were in good agreement with those published in the literature earlier. A great interindividual variability for PK parameters from 44.5% up to 167% was revealed. Different regression lines between meropenem clearance and clearance creatinine (CLCr) were registered in patients with CLCr [1] 7 L/h versus > 7 L/h: statistically significant regression (n=30, p=0.015) versus no correlation (n=6, р=0.85), respectively. Bayesian feedback TDM-based meropenem dose personalization is the most practical approach to ensure adequate drug exposure in critically ill patients, especially in patients with augmented renal clearance.

Published
2022
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35. Orientation of thin YBa2Cu3O7-delta/YSZ films characterization by micro-Raman spectroscopy

Author

Choon Kiat Ong, W Z Zhou, S Y Xu, M S Chen, and Zexiang Shen

Subjects
Materials science, Scattering, Metals and Alloys, Analytical chemistry, Condensed Matter Physics, Crystallographic defect, Pulsed laser deposition, symbols.namesake, Carbon film, Materials Chemistry, Ceramics and Composites, symbols, Cubic zirconia, Electrical and Electronic Engineering, Thin film, Raman spectroscopy, Yttria-stabilized zirconia
Abstract

Micro-Raman scattering of thin YBa2Cu3O7- films of various thicknesses, deposited by pulsed laser deposition on the yttrium-stabilized zirconia (001) substrates, was carried out at different scattering geometries. The fraction of c-axis orientation of the films was calculated from the intensity ratio of the O(2,3)-B1g and O(4)-Ag modes. It is shown that it is strongly dependent on the film thickness and the highest fraction of c-axis orientation occurs for film thickness around 80 nm. The lower c-axis fraction for thinner films was explained by the simultaneous growth of a- and c-axis-oriented grains at the interface region, while the lower c-axis fraction for thicker films was due to the faults and voids in the films. Several a- and b-axis in-plane orientations have been identified using polarized Raman spectra.

Published
1999
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36. The distribution of Ag in Ag-doped YBa2Cu3O7-deltathin film prepared by dual-beam pulsed-laser deposition

Author

Y P Feng, D H C Chua, Choon Kiat Ong, S Y Xu, M S Chen, W Z Zhou, and T Osipowicz

Subjects
Auger electron spectroscopy, Materials science, Scanning electron microscope, Doping, Metals and Alloys, Oxide, Condensed Matter Physics, Microstructure, Pulsed laser deposition, chemistry.chemical_compound, chemistry, Materials Chemistry, Ceramics and Composites, Electrical and Electronic Engineering, Composite material, Thin film, Deposition (law)
Abstract

The Ag distribution in Ag-doped YBa2Cu3O7- (YBCO) thin films fabricated by dual-beam pulsed-laser deposition on SrTiO3 (100) substrates has been studied by Auger electron spectroscopy, microproton-induced x-ray emission, atomic force microscopy and scanning electron microscopy. All the results consistently show that Ag aggregated in the bar-like structures observed in the film. These bars are aligned along the a-b-axis or at 45° to the a-b-axis of the YBCO thin film. The main body of the long bars aligned with the a-b-axes of the film was found to be a combination of metallic Ag with other precipitates of YBCO film that may grow from the substrate surface to the YBCO film surface. There were other precipitates aggregating as well at the surface of these bars, such as oxides of Cu and Ba. The short bars that aligned along 45° to the a-b-axes of the film were found to be deficient in Ag but rich in Cu, Ba and O, which could be oxide precipitates of YBCO. The growth mechanisms of the two types of bars seem quite different.

Published
1999
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37. Energetics Of Bipedal Running II. Limb Design and Running Mechanics

Author

Charles R. Taylor, Thomas J. Roberts, and M S Chen

Subjects
Male, Force generation, Turkeys, Physiology, STRIDE, Aquatic Science, Biology, Muscle volume, Body weight, Models, Biological, Running, Dogs, Species Specificity, Relative Volume, Animals, Mechanical advantage, Muscle, Skeletal, Gait, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Body Weight, Energetics, Extremities, Anatomy, Biomechanical Phenomena, Insect Science, Fascicle length, Female, Animal Science and Zoology, Energy Metabolism, Muscle Contraction
Abstract

Compared with quadrupeds, bipedal runners of the same weight have longer legs, take longer steps and can presumably use slower, more economical muscle fibers. One might predict that bipedal running is less expensive, but it is not. We hypothesized that bipeds recruit a larger volume of muscle to support their weight, eliminating the potential economy of longer legs and slower steps. To test our hypothesis, we calculated the relative volume of muscle needed to support body weight over a stride in small dogs (Canis familiaris) and wild turkeys (Meleagris gallopavo) of the same weight. First, we confirmed that turkeys and dogs use approximately the same amount of energy to run at the same speed, and found that turkeys take 1.8-fold longer steps. Higher muscle forces and/or longer muscle fibers would require a greater volume of active muscle, since muscle volume is proportional to the product of force and fascicle length. We measured both mean fascicle length and mean mechanical advantage for limb extensor muscles. Turkeys generated approximately the same total muscle force to support their weight during running and used muscle fascicles that are on average 2.1 times as long as in dogs, thus requiring a 2.5-fold greater active muscle volume. The greater volume appears to offset the economy of slower rates of force generation, supporting our hypothesis and providing a simple explanation for why it costs the same to run on two and four legs.

Published
1998
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38. Video versus lecture: effective alternatives for orthodontic auxiliary training

Author

E N Horrocks, M S Chen, and R D Evans

Subjects
Attitude of Health Personnel, Orthodontic Brackets, Teaching method, Dental auxiliary, education.educational_degree, Dentistry, Orthodontics, Dental Assistants, Surveys and Questionnaires, Image Processing, Computer-Assisted, Humans, Medicine, Prospective Studies, education, Audiovisual Aids, business.industry, Teaching, Dental Assistant, Bracket, Significant difference, Dental Bonding, Videotape Recording, Dental Models, General Medicine, Models, Dental, Orthodontic brackets, Dental Auxiliaries, Dental Hygienists, business
Abstract

Many studies have compared the relative effectiveness of visually-aided lectures and videotapes, but methodological flaws have prevented definitive comparison of the techniques. This study assessed the relative effectiveness of the two approaches for orthodontic auxiliary training. This study was a prospective, randomised trial, conducted at the Eastman Dental Hospital and Institute. Two groups of 16 dental auxiliaries, selected at random, studied identification and positioning of orthodontic brackets: one group attended a lecture accompanied by slides and the other viewed a video. Subjects bonded brackets onto acrylic teeth and the results were assessed by computerised image analysis. The subjects completed a questionnaire on their attitudes to the respective teaching methods. Results were assessed for accuracy of bracket placement and variations in type of auxiliary. There was no significant difference between the teaching methods except for bracket positioning where video was slightly better (P < 0.05). There was no significant difference between the types of auxiliary. Generally, video teaching and lecturing were equally effective, with video achieving slightly better results. Both methods were effective at teaching bracket placement, and dental nurses and student hygienists proved equally adept at bracket positioning.

Published
1998
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39. Calculation of Electrohydrodynamic Flow in a Circular Cylindrical Conduit

Author

M. S. Chen, R. Watson, Sean McKee, J. Caldwell, and José Alberto Cuminato

Subjects
Shooting method, Flow velocity, Differential equation, Drag, Applied Mathematics, Ordinary differential equation, Numerical analysis, Mathematical analysis, Computational Mechanics, Finite difference method, Linear equation, Mathematics
Abstract

The electrohydrodynamic flow of a fluid in an “ion drag” configuration in a circular cylindrical conduit is governed by a non-linear second-order ordinary differential equation. The degree of non-linearity in this equation is determined by a nondimensional parameter α and the equation can be approximated by two different linear equations for very small or very large values of α respectively. Perturbation solutions of the fluid velocities for α ≪ 1 and α ≫ 1 are developed. A Gauss-Newton finite-difference solver combined with the continuation method and a Runge-Kutta shooting method are used to provide numerical results for the fluid velocity over a large range of values of α. Both numerical and analytical results are compared in order to establish the range of validity for the perturbation solutions. Die elektrohydrodynamische Stromung in einer „ion-drag”-Konfiguration in einem kreiszylindrischen Rohr wird durch eine nichtlineare gewohnliche Differentialgleichung 2. Ordnung beschrieben. Der Grad der Nichtlinearitat dieser Gleichung wird durch einen dimensionslosen Parameter a bestimmt, und die Gleichung kann durch zwei verschiedene lineare Gleichungen fur sehr kleine bzw. sehr grose Werte von α approximiert werden. Die Storungslosungen der Fluidgeschwindigkeiten fur α ≪ 1 und α ≫ 1 werden hergeleitet. Ein Gaus-Newton Finite-Differenz-Losungsverfahren, kombiniert mit der Fortsetzungsmethode und einem Runge-Kutta Shooting-Verfahren werden benutzt, um numerische Resultate fur die Stromungsgeschwindigkeit uber einen grosen α-Bereich herzuleiten. Die numerischen und analytischen Resultate werden verglichen, um den Gultigkeitsbereich der Storungslosungen festzustellen.

Published
1997
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40. Quantitative analysis of contrast-enhanced ultrasonography: differentiating focal nodular hyperplasia from hepatocellular carcinoma

Author

Mu Yan Cai, Anhua Li, Yong Hong Xiong, M. S. Chen, Xiao-qing Pei, Long Zhong Liu, and Ru Hai Zou

Subjects
Adult, Male, medicine.medical_specialty, Carcinoma, Hepatocellular, Sulfur Hexafluoride, Contrast Media, Sensitivity and Specificity, Diagnosis, Differential, Young Adult, Late phase, Carcinoma, Medicine, Humans, Radiology, Nuclear Medicine and imaging, Phospholipids, Retrospective Studies, Ultrasonography, Observer Variation, business.industry, Liver Neoplasms, Focal nodular hyperplasia, General Medicine, Full Papers, Middle Aged, medicine.disease, Image Enhancement, Focal Nodular Hyperplasia, Hepatocellular carcinoma, Injections, Intravenous, Time to peak, Female, Radiology, Differential diagnosis, business, Quantitative analysis (chemistry)
Abstract

To explore the potential of quantitative analysis of contrast-enhanced ultrasonography (CEUS) in differentiating focal nodular hyperplasia (FNH) from hepatocellular carcinoma (HCC).34 cases of FNH and 66 cases of HCC (all lesions5 cm) were studied using CEUS to evaluate enhancement patterns and using analytic software Sonoliver® (Image-Arena™ v.4.0, TomTec Imaging Systems, Munich, Germany) to obtain quantitative features of CEUS in the region of interest. The quantitative features of maximum of intensity (IMAX), rise slope (RS), rise time (RT) and time to peak (TTP) were compared between the two groups and applied to further characterise both FNH and HCC with hypoenhancing patterns in the late phase on CEUS.The sensitivity and specificity of CEUS for diagnosis of FNH were 67.6% and 93.9%, respectively. For quantitative analysis, IMAX and RS in FNHs were significantly higher than those in HCCs (p0.05), while RT and TTP in FNHs were significantly shorter (p0.05). Both the 11 FNHs and 62 HCCs with hypo-enhancing patterns in the late phase were further characterised with their quantitative features, and the sensitivity and specificity of IMAX for diagnosis of FNH were 90.9% and 43.5%, RS 81.8% and 80.6%, RT 90.9% and 71.0%, and TTP 90.9% and 71.0%, respectively.The quantitative features of CEUS in FNH and HCC were significantly different, and they could further differentiate FNH from HCC following conventional CEUS.Our findings suggest that quantitative analysis of CEUS can improve the accuracy of differentiating FNH from HCC.

Published
2013

41. Hepatocellular Carcinoma Screening Practices and Impact on Survival among Hepatitis B-Infected Asian Americans

Author

M, Sarkar, S, Stewart, A, Yu, M S, Chen, T T, Nguyen, and M, Khalili

Subjects
Adult, Aged, 80 and over, Male, Carcinoma, Hepatocellular, Asian, Middle Aged, Survival Analysis, digestive system diseases, Article, Cohort Studies, Hepatitis B, Chronic, Humans, Female, San Francisco, neoplasms, Early Detection of Cancer, Aged, Retrospective Studies
Abstract

Asians Americans have a high burden of hepatitis B virus (HBV) associated hepatocellular carcinoma (HCC). HCC screening practices in this population are unknown. We aimed to investigate predictors and patterns of HCC screening and its impact on survival in HBV-infected Asian Americans. Clinical data were obtained from a retrospective cohort of 1870 HBsAg-positive Asians in San Francisco's safety net clinics. In 824 patients at-risk for HCC, screening (≥1 imaging and/or AFP per year) decreased from 67% to 47% to 24% from the 1st to 2nd to 10th year after HBV diagnosis, respectively. AFP, imaging, and imaging plus AFP were used in 37%, 14%, and 49% during the first year after diagnosis, and imaging plus AFP increased to 64% by the 10th year. Among 1431 patients followed in 2007, age 40-64 years, female gender, cirrhosis, hepatologist evaluation, HBV diagnosis after 2003, and testing for HBeAg were associated with HCC screening. Of the 51 patients with HCC, more cirrhotics received screening and were diagnosed with early stage disease. Median survival following HCC diagnosis was higher in screened patients (1624 days vs. 111 days, P = 0.02). MELD score at HCC diagnosis (HR 1.2, 95% CI 1.1-1.3) and receipt of curative therapy (HR 0.3, 95% CI 0.08-0.94) were associated with survival. Screening rates in at-risk Asian Americans, particularly among noncirrhotics, were suboptimal and decreased over time. Among patients with HCC, receipt of prior screening improved survival, and this survival benefit was related to better liver function at HCC diagnosis and receipt of curative therapy.

Published
2012

42. 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo

Author

S A Lacy, M S Chen, Z H Li, K M Kent, William A. Lee, N Bischofberger, Dirk B. Mendel, K C Cundy, Michael J. M. Hitchcock, and D.B. Barkhimer

Subjects
Male, Organophosphonates, Biology, medicine.disease_cause, Antiviral Agents, Rats, Sprague-Dawley, Cytosine, Mice, chemistry.chemical_compound, Organophosphorus Compounds, Therapeutic index, Drug Stability, In vivo, medicine, Animals, Humans, Choline, Prodrugs, Pharmacology (medical), Cytotoxicity, Cells, Cultured, Pharmacology, virus diseases, Prodrug, Molecular biology, In vitro, Rats, Infectious Diseases, Herpes simplex virus, chemistry, Biochemistry, Female, Cidofovir, Research Article
Abstract

1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosi ne (cyclic [cHPMPC]) was evaluated as a novel antiviral agent in comparison with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). Evaluation for in vitro activity against herpes simplex virus type 2 in MA-104 and MRC-5 cells showed that both cHPMPC and HPMPC have comparable activities and cytotoxicities. cHPMPC was found to be stable on incubation in human plasma and human liver homogenates. Intracellular metabolism studies revealed that cHPMPC was converted inside of the cells to HPMPC and then to the monophosphate, the diphosphate, and the monophosphate choline metabolites. In a mouse herpes simplex virus type 2 encephalitis model, both cHPMPC and HPMPC exhibited similar potencies in vivo. Nephrotoxicity, which is the dose-limiting toxicity of HPMPC, was assessed in a 14-day repeated-dose toxicity study in rats; cHPMPC has an improved safety margin of > or = 13-fold over that of HPMPC.

Published
1994
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43. Fourth meeting of the European Neurological Society 25–29 June 1994 Barcelona, Spain

Author

H. Hattig, C. Delli Pizzi, M. C. Addonizio, Michelle Davis, A. R. Giovagnoli, L. Florensa, M. Roth, J. de Kruijk, Francisco Lacruz, Ph. Dewailly, A. Toygar, C. Avendano, P.P. De Deyn, J. F. Hurtevent, F. Lomeila, T. W. Wong, Gordon T. Plant, M. Bud, H. J. Willison, DH Miller, D. W. Langdon, R. Cioni, J. Servan, A. Kaygisiz, E. Racadot, D. B. Schens, E. Picciola, L. Falip, C. Bouchard, J. Jotova, A. Jorge-Santamaria, P. Misra, A. Dufour, C. P. Panagopoulos, A. Venneri, B. Sredni, B. Angelard, M. Janelidze, M. Carreno, J. Obenberger, J. Pouget, H. W. Moser, R. Kaufmann, J. A. Molina, D. Linden, A. Martin Urda, E. Uvestad, A. Krone, J. P. Cochin, J. Mallecourt, A. Cambon-Thomsen, K. Violleau, P. Osschmann, A. M. Durocher, E. Bussaglia, D. M. Danielle, H. Efendi, C. Van Broeckhoven, K. G. Jordan, W. Rautenberg, C. Iniguez, J. M. Delgado, Graham Watson, M. Lawden, Gareth J. Barker, K. Stiasny, James T. Becker, G. Campanella, E. Peghi, A. Poli, A. Haddad, T. Yamawaki, Giacomo P. Comi, S. Sotgiu, B. Ersmark, A. Pomes, M. Ziegler, P. Ferrante, P. Ruppi, H. KuÇukoglu, R. Bouton, U. K. Rinne, P. Vieregge, M. Dary, P. Giunti, Peter J. Goadsby, S. Jung, E. Secor, A. Steinberg, N. Vila, M. A. Hernandez, M. Cursi, A. Enqelhardt, A. Engelhardt, J. Veitch, F. Di Silverio, F. Arnaud, B. Neundörfer, R. Brucher, Dominique Caparros-Lefebvre, B. Meyer, Marianne Dieterich, M. H. Snidaro, R. Gomez, R. Cerbo, M. Ragno, J. M. Vance, S. Nemni, A. Caliskan, F. Barros, I. Velcheva, D. Ceballos-Baumann, V. Barak, A. Avila, N. Antonova, F. Resche, S. Pappata, L. Varela, S. R. Silveira Santos, A. Cammarota, L. Naccache, Y. Nara, E. Tournier-Lasserves, R. Mobner, T. Chase, A. Ensenyat, J. Ulrich, G. Giegerich, M. Rother, M. Revilla, N. Nitschke, K. Honczarenko, E. Basart Tarrats, J. Blin, B. Jacob, J. Santamaria, S. Knezevic, J. L. Castillo, M. Antem, J. Colomer, O. Busse, Didier Hannequin, S. Carrier, J. B. Ruidavets, C. Rozman, J. Bogoussslavsky, J. Pascual Calvet, E. Monros, J. M. Polo, M. Zucconl, Javier Muruzabal, R. R. Allen, R. Rivolta, K. Haugaard, A. Nespolo, K. Hoang-Xuang, G. Bussone, T. Avramidis, E. Corsini, Christiana Franke, T. Vinogradova, H. Boot, K. Vestergaard, G. H. Jansen, N. Argentino, M. Raltzig, W. Linssen, Mark B. Pepys, P. Roblot, L. Lauritzen, E. Fainardi, D. Morin, T. X. Arbizu Urdiain, J. Wollenhaupt, S. Bostantjopoulou, G. Pavesi, A. D. Forman, Giovanni Fabbrini, D. Jean, J. J. Archelos, M. I. Blanchs, M. Del Gobbo, Anna Carla Turconi, Ch. Derouesné, Elio Scarpini, A. Visbeck, P. Castejon, J. P. Renou, F. Mounier-Vehier, G. Potagas, Ch. Duyckaerts, A. Filla, R. Schneider, G. Ronen, K. Nagata, J. P. Vedel, A. Henneberg, G. van Melle, C. Baratti, H. Knott, M. C. Prevett, A. Bes, B. Metin, Jos V. Reempts, L. Martorell, Mefkure Eraksoy, H. O. Handwerker, D. S. Younger, O. Oktem, D. Frongillo, C. Soriano-Soriano, L. Niehaus, F. Zipp, A. Tartaro, S Newman, R. H. Browne, P. Davous, R. Sanchez, M. Muros, M. E. Kornhuber, A. Lavarone, M. Mohr, M. R. Garcia, S. Russell, H. Kellar-Wood, M. R. Tola, B. Ostermeyer, Ch. Tzekov, K. Sartor, E. B. Ringelstein, P. P. Gazzaniga, Paul Krack, H. Fidaner, H. Rico, T. Dbaiss, F. Alameda, E. Torchiana, L. Rumbach, I. Charques, J. M. Bogaard, C. D. Frith, L. J. Rappelle, R. Brenner, A. Joutel, K. Fuxe, G. HÄcker, M. J. Blaser, J. Valls-SolÇ, G. Ulm, M. Alberdi, A. Bock, F. W. Bertelsmann, U. Wieshmann, J. Visa, J. R. Lupski, D. D'Amico, L. M. P. Ramos, A. A. Vanderbark, R. Horn, M. Warmuth, Dietmar Kühne, Mark S. Palmer, C. Ehrenheim, E. Canga, S. Viola, O. Scarpino, P. Naldi, R. Almeida, A. A. Raymond, J. Gamez, Stephan Arnold, A. DiGiovanni, J. Dalmau, C. C. Chari, H. F. Beer, J. C. Koetsier, J. Iriarte, E. Yunis, J. Casadevall, E. Le Guern, E. Stenager, S. R. Benbadis, J. M. Warter, F. Burklin, I. Theodorou, L. Johannesen, G. A. Graveland, X. Leclerc, I. Vecchio, L. Ozelius, G. Nicoletti, R. K. Gherardi, E. Esperet, M. L. Delodovici, F. Cattin, F. Paiau, Giorgio Sacilotto, C. A. J. Broere, D. Chavdarov, J. P. Willmer, C. H. Hawkes, Th. Naegele, E. Ellie, E. Dartigues, M. J. Guardiola, S. Hesse, Z. Levic, Marco Rovaris, P. Saugeir-Veber, B. A. Yaqub, H. F. Durwen, R. Larumbe, J. Ballabrina, M. Sendtner, J. Röther, M. Horstink, C. Kluglein, M.P. Montesi, H. Apaydin, J. Montoya, E. Waubant, Ch. Verellen-Dunoulin, A. Nicolai, J. Lopez-Delval, R. Lemon, G. Cantinho, E. Granieri, A. Zeviani, Wolfgang H. Oertel, U. Ficola, V. Di Piero, V. Fragola, K. Sabev, M. V. Guitera, I. Turki, F. Bolgert, P. Ingrand, J. M. Gobernado, L. M. E. Grimaldi, S. Baybas, B. Eymard, Y. Rolland, Y. Robitaille, Ta. Pampols, P. J. Koehler, A. Carroacedo, J. Vilchez, S. Di Vittorio, I. R. Rise, T. Nagy, M. Kuffner, E. Palazzini, A. Ott, J. Pruim, T. X. Arbizu, E. Manetti, C. Cervera, S. Felber, G. Gursoy, J. Scholz, G. A. Buscaino, M. S. Chen, A. Pascual, J. Hazan, J. U. Gajda, J. G. Cea, G. Bottini, G. Damalik, F. Le Doze, G. Bonaldi, J. M. Hew, C. Messina, A. M. Kennedy, J. M. Carney, N. M. F. Murray, M. Parent, M. Koepp, V. Dimova, D. De Leo, K. Jellinger, G. Salemi, S. Mientus, M. L. Hansen, F. Mazzucchelli, J. Vieth, M. Mauri, E. Bartels, L. Johannsen, C. Humphreys, J. Emile, D. N. Landon, E. Kansu, R. Sanchez-Pernaute, Rsj Frackowiak, M. Gonzalez Torres, L. Oller, C. Machedo, J. Kother, M. Billiard, H. Durak, T. Schindler, A. Frank, A. Uncini, A. Sbriccoli, C. Farinas, D. W. Paty, N. Fast, A. T. Zangaladze, A. Kerkhofs, J. M. Pino Garcia, I. De la Fuente, B. Marini, L. Gomez, I. Rubio, Alessandra Bardoni, C. Brodie, P. Acin, U. Sliwka, S. A. Hawkins, S. Tardieu, F. Vitullo, J. M. Pereira Monteino, R. Gagliardi, T. Jezewski, A. Cano, T. Lempert, F. Abad Alegria, G. Rotondo, D. Ince, C. Martinez Parra, Y. Huang, H. Luders, Y. Steinvil, F. G. A. Van Der Meche, R. Bianchi, A. Sanchez, T. Sevilla, J. M. Ketelslegers, A. Domzal-Stryga, M. Pandolfo, M. O. Josse, K. W. Neff, I. Blanco, G. W. Bruyn, O. W. Witte, J. L. Thibault, G. Andersen, J. Pariset, A. Marcone, R. J. M. Lane, A. Hofman, M. Verin, T. Matilla, P. Bedoucha, J. Roche, M. Lai, M. Collard, A. Ugarte, F. Gallecho, D. Silbersweig, C. Kennard, J. P. Azulay, T. W. Ho, P. L. I. Dellemijn, R. Girardello, F. Baas, B. Voss, F. Rozenberg, E. M. Brocker, V. Stanev, A. A. J. Soeterboek, A. Marra, A. Rey, E. Ertem, M. Sawradewicz-Rybak, J. De Keyser, P. Cavallari, F. Proust, Y. Chevalier, H. C. Hansen, D. Leys, C. A. Davie, K. Hoang-Xuan, C. Bairati, H. van Crevel, Thomas T. Warner, B. Bompais, A. Dobbeleir, T Campbell, C. Macko, C. J. M. Klijn, M. Dussallant, T. P. Berlit, W. Rozenbaum, M. J. van den Bent, W. A. Rocca, M. Muller, H. Hundemer, U. Zifko, M. Campera, F. Drislane, D. Ranoux, T. M. Kloss, Anil Kumar, I. Ruolt, C. Bargnani, B. Marescau, N. A. Losseff, S. Notermans, B. Kint, E. T. Burke, C. Aykut, J. Matias Guiu, P. Maquet, T. Drogendijk, M. Leone, K. von Ammon, M. Pepeliarska, C. Prados, L. DiGiamberardino, T. Logtenberg, G. Lenoir, I. Castaldo, Damhaut, M. Radionova, G. Sirabian, R. 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Frigo, Leif Østergaard, J. L. Munoz Blanco, A. Cruz-Matinez, J. De Reuck, C. Theillet, T. Barroso, V. Oikonen, Florence Lebert, M. Kilinc, C. Cordon-Cardon, G. Stoll, E. Thiery, F. Pulcinelli, J. Solski, M. Schmiegelow, L. J. Polman, P. Fernandez-Calle, C. Wikkelso, M. Ben Hamida, M. Laska, E. Kott, W. Sulkowski, C. Lucas, N. M. Bornstein, D. Schmitz, M. W. Lammers, A. de Louw, R. J. S. Wise, P. A. van Darn, C. Antozzi, P. Villanueva, P. H. E. Hilkens, C. Constantin, W. Ricart, A. Wolf, M. Gamba, P. Maguire, Alessandro Padovani, B. M. Patten, Marie Sarazin, H. Ackermann, L. Durelli, S. Timsit, Sebastian Jander, B. W. Scheithauer, G. Demir, J. P. Neau, P. Barbanti, A. Brand, N. AraÇ, V. Fischer-Gagnepain, R. Marchioli, G. Serratrice, C. Maugard-Louboutin, G. T. Spencer, D. Lücke, G. Mainardi, K. Harmant Van Rijckevorsel, G. B. Creel, R. Manzanares, Francesco Fortunato, A. May, J. Workman, K. Johkura, E. Fernandez, Carlo Colosimo, L. Calliauw, L. Bet, Félix F. Cruz-Sánchez, M. Dhib, H. Meinardi, F. Carrara, J. Kuehnen, C. Peiro, H. Lassmann, K. Skovgaard Olsen, A. McDonald, L. Sciulli, A. Cobo, A. Monticelli, B. Conrad, J. Bagunya, J. Benitez, V. Desnizza, B. Dupont, O. Delrieu, D. Moraes, J. J. Heimans, F. Garcia Rio, M. Matsumto, A. Fernandez, R. Nermni, R. Chalmers, M. J. Marchau, F. Aguado, P. Velupillai, P. J. Martin, P. Tassan, V. Demarin, A. Engelien, T. Gerriets, Comar, J. L. Carrasco, J. P. Pruvo, A. Lopez de Munain, D. Pavitt, J. Alarcon, Chris H. Polman, B. Guldin, N. Yeni, Hartmut Brückmann, N. Wilczak, H. Szwed, R. Causaran, G. Kyriazis, M. E. Westarp, M. Gasparini, N. Pecora, J. M. Roda, E. Lang, V. Scaioli, David R. Fish, D. Caputo, O. Gratzl, R. Mercelis, A. Perretti, G. Steimetz, I. Link, C. Rigoletto, A. Catafau, G. Lucotte, M. Buti, G. Fagiolari, A. Piqueras, C. Godinot, J. C. Meurice, Erodriguez J. Dominigo, F. Lionnet, H. Grzelec, David J. Brooks, P. M. G. Munro, F. X. Weilbach, M. Maiwald, W. Split, B. Widjaja-Cramer, V. Ozturk, J. Colas, E. Brizioli, J. Calleja, L. Publio, M. Desi, R. Soffietti, P. Cortinovis-Tourniaire, E. F. Gonano, G. Cavaletti, S. Uselli, K. Westerlind, H. Betuel, C. O. Dhiver, H. Guggenheim, M. Hamon, R. Fazio, P. Lehikoinen, A. Esser, B. Sadzot, G. Fink, Angelo Antonini, D. Bendahan, V. Di Carlo, G. Galardi, A. F. Boller, M. Aksenova, Del Fiore, V. de la Sayette, H. Chabriat, A. Nicoletti, A. Dilouya, M. L. Harpin, E. Rouillet, J. Stam, A. Wolters, M. R. Delgado, Eduardo Tolosa, G. Said, A. J. Lees, L. Rinaldi, A. Schulze-Bonhage, MA Ron, C. Lefebvre, E. W. Radü, R. Alvarez, M. L. Bots, P. Reganati, S. Palazzi, A. Poggi, N. J. Scolding, V. Sazdovitch, T. Moreau, E. Maes, M. A. Estelies, P. Petkova, Jose-Felix Marti-Masso, G De La Meilleure, N. Mullatti, M. Rodegher, N. C. Notermans, T. A. T. Warner, S. Aktan, J. P. Louboutin, L. Volpe, C. Scheidt, W. Aust, C. M. Wiles, U. Schneider, S. K. Braekken, W. R. Willems, K. Usuku, Peter M. Rothwell, C. Talamon, M. L. Sacchetti, A. Codina, M. H. Marion, A. Santoro, J. Roda, A. Bordoni, D. J. Taylor, S. Ertas, H. H. Emmen, J. Vichez, V. BesanÇon, R. E. Passingham, M. L. Malosio, A. Vérier, M. Bamberg, A. W. Hansen, E. Mostacero, G. Gaudriault, Marie Vidailhet, B. Birebent, K. Strijckmans, F. Giannini, T. Kammer, I. Araujo, J. Nowicki, E. Nikolov, A. Hutzelmann, R. Gherardi, J. Verroust, L. Austoni, A. Scheller, A. Vazquez, S. Matheron, H. Holthausen, J. M. Gerard, M. Bataillard, S. Dethy, V. H. Patterson, V. Ivanez, N. P. Hirsch, F. Ozer, M. Sutter, C. Jacomet, M. Mora, Bruno Colombo, A. Sarropoulos, T. H. Papapetropoulos, M. Schwarz, D. S. Dinner, N. Acarin, B. Iandolo, J. O. Riis, P. R. J. Barnes, F. Taroni, J. Kazenwadel, L. Torre, A. Lugaresi, I. L. Henriques, S. Pauli, S. Alfonso, Pedro Quesada, A. S. T. Planting, J. M. Castilla, Thomas Gasser, M. Van der Linden, A. Alfaro, E. Nobile-Orazio, G. Popova, W. Vaalburg, F. G. A. van der Mech, L. Williams, F. Medina, J. P. Vernant, J. Yaouanq, B. Storch-Hagenlocher, A. Potemkowski, R. Riva, M. H. Mahagne, M. Ozturk, Ve. Drory, N. Konic, C. Jungreis, A. Pou Serradell, J. L. Gauvrit, G. J. Chelune, S. Hermandez, T. Dingus, L. Hewer, Ch. Koch, M. N. Metz-Lutz, G. Parlato, M. Sinaki, Charles Pierrot-Deseilligny, H. C. Diener, J. Broeckx, J. Weill-Fulazza, M. L. Villar, M. Rizzo, O. Ganslandt, C. Duran, N. A. Fletcher, G. Di Giovacchino, Susan T. Iannaccone, C. Kolig, N. Fabre, H. A. Crockard, Rita Bella, M. Tazir, E. Papagiannuli, K. Overgaard, Emma Ciafaloni, I. Lorenzetti, F. Viader, P. A. H. Millac, I. Montiel, L. H. Visser, M. Palomar, P. L. Murgia, H. Pedersen, Rafael Blesa, S. Seddigh, W. O. Renier, I. Lemahieu, H. M. L. Jansen, L. Rosin, J. Galofre, K. Mattos, M. Pondal, G. M. Hadjigeorgiou, D. Francis, L. Cantin, D. Stegeman, M. Rango, A. B. M. F. Karim, S. Schraff, B. Castellotti, I. Iriarte, E. Laborde, T. J. Tjan, R. Mutani, D. Toni, B. Bergaasco, J. G. Young, C. Klotzsch, A. Zincone, X. Ducrocq, M. Uchuya, O. J. Kolar, A. Quattrone, T. Bauermann, Nereo Bresolin, J. Vallée, B. C. Jacobs, A. Campos, Werner Poewe, J. A. Villanueva, A. W. Kornhuber, A. Malafosse, E. Diez-Tejedor, G. Jungreia, M. J. A. Puchner, A. Komiyama, O. Saribas, V. Volpini, L. Geremia, S. Bressi, A. Nibbio, Timothy E. Bates, T. z. Tzonev, E. Ideman, G. A. Damlacik, G. Martino, G. Crepaldi, T. Martino, Kjell Någren, E. Idiman, D. Samuel, J. M. Perez Trullen, Y. van der Graaf, J. O. Thorell, M. J. M. Dupuis, E. Sieber, R. D'Alessandro, C. Cazzaniga, J. Faiss, A. Tanguy, A. Schick, I. Hoksergen, A. Cardozo, R. Shakarishvili, G. K. Wennlng, J. L. Marti-Vilalta, J. Weissenbach, I. L. Simone, Amalia C. Bruni, Darius J. Adams, C. Weiller, A. Pietrangeli, F. Croria, C. Vigo-Pelfrey, Patricia Limousin, A. Ducros, G. Conti, O. Lindvall, E. Richter, M. Zuffi, A. Nappo, T. Riise, J. Wijdenes, M. J. Fernandez, J. Rosell, P. Vermersh, S. Servidei, M. S. C. Verdugo, F. Gouttiere, W. Solbach, M. Malbezin, I. S. Watanabe, A. Tumac, W. I. McDonald, D. A. Butterfield, P. P. Costa, F. deRino, F. Bamonti, J. M. Cesar, C. H. Lahoz, I. Mosely, M. Starck, M. H. Lemaitre, K. M. Stephan, S. Tex, R. Bokonjic, I. Mollee, L. Pastena, M. Gutierrez, F. Boiler, M. C. Martinez-Para, M. Velicogna, O. Obuz, A. Grinspan, M. Guarino, L. M. Cartier, E. Ruiz, D. Gambi, S. Messina, M. Villa, Michael G. Hanna, J. Valk, Leone Pascual, M. Clanet, Z. Argov, B. Ryniewicz, E. Magni, B. Berlanga, K. S. Wong, C. Gellera, C. Prevost, F. Gonzalez-Huix, R. Petraroli, J. E. G. Benedikz, I. Kojder, C. Bommelaer, L. Perusse, M. R. Bangioanni, Guy M. McKhann, A. Molina, C. Fresquet, E. Sindern, Florence Pasquier, M. J. Rosas, M. Altieri, O. Simoncini, M. Koutroumanidis, C. A. F. Tulleken, M. Dary-Auriol, S. Oueslati, H. Kruyer, I. Nishisho, C. R. Horning, A. Vital, G. V. Czettritz, J. Ph. Neau, B. Mihout, A. Ameri, M. Francis, S. Quasthoff, D. Taussig, S. Blunt, P. Valentin, C. Y. Gao, O. Heinzlef, H. d'Allens, C. Coudero, M. Erfas, G. Borghero, P. J. Modrego Pardo, M. C. Patrosso, N. L. Gershfeld, P. A. J. M. Boon, O. Sabouraud, M. Lara, J. Svennevig, G. L. Lenzi, A. Barrio, H. Villaroya, JosÇ M. Manubens, O. Boespflug-Tanguy, M. Carreras, D. A. Costiga, J. P. Breux, S. Lynn, C. Oliveras Ley, A. G. Herbaut, J. Nos, C. Tornali, Y. A. Hekster, J. L. Chopard, J. M. Manubens, P. Chemouilli, A. Jovicic, F. Dworzak, S. Smirne, S. E. Soudain, B. Gallano, D. Lubach, G. Masullo, G. Izquierdo, A. Pascual Leone Pascual, A. Sessa, V. Freitas, O. Crambes, L. Ouss, G. W. Van Dijk, P. Marchettini, P. Confalonieri, M. Donaghy, A. Munnich, M. Corbo, and M. E. L. van der Burg

Subjects
Neurology, business.industry, Media studies, Library science, Medicine, Neurology (clinical), business
Published
1994
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45. Application of Time-frequency Attributes Based on Generalized S-transform for Thin Bed Indication

Author

H. Y. Zhang, Z. H. Wan, R. D. Han, and M. S. Chen

Subjects
Regional geology, Channel (digital image), Engineering geology, Short-time Fourier transform, Economic geology, Petrology, Algorithm, Geology, Physics::Geophysics, Time–frequency analysis, Environmental geology, Matrix decomposition
Abstract

During the last decade, spectral decomposition technique has proven to be an excellent tool to describe thin beds associated with channel sands, alluvial fans, and the like. However, the traditional spectral decomposition method based on short time Fourier transform, is difficult to acquire the accurate time-frequency spectrum for non-stationary seismic signals. In addition, it generates dozens of unwieldy iso-frequency cubes, not amenable for interpretation. We propose two new time-frequency attributes based on generalized S-transform and apply them to an oilfield of western China to characterize the Triassic reservoir distribution of fluvial deposits. Compared with the traditional short time Fourier transform, the generalized S transform results in more accurate time-frequency spectrum, and generate two attributes which can directly map reservoir thickness.

Published
2011
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46. Characterization of junction dosage effect on NAND arrays with charge pumping method

Author

S.H. Ku, K. F. Chen, Chih-Yuan Lu, I. J. Huang, L. H. Chong, C. H. Lee, Tahui Wang, N.K. Zous, T. T. Han, C. H. Cheng, Chienying Lee, M. S. Chen, W. P. Lu, J. S. Huang, Kuang-Chao Chen, and Y. J. Chen

Subjects
Physics, Amplitude, Reliability (semiconductor), business.industry, Logic gate, Electrical engineering, NAND gate, Optoelectronics, High-pass filter, business, Noise (electronics), Hot-carrier injection, Threshold voltage
Abstract

Reliability issues including random telegraph noise (RTN) and program disturbance in floating gate (FG) NAND strings for different junction dosages are compared. Although the initial threshold voltage (V T ) distributions are similar for various source/drain (S/D) dosages, these samples exhibit different amplitudes on read current fluctuation. This current noise will induce inaccuracy in sensing level and the read margin is reduced especially for multi-level cell (MLC) operation. Moreover, the junction profile has a strong impact on program disturbance. Contrary to the behavior of global self-boosting (GSB), the V T of disturbed bits show an abnormal tail distribution under high pass gate voltage (V pass, pgm ) when junction dosage is reduced. Charge pumping technique is utilized to explore the local V T distribution around junctions. Based on our characterization results, the hot-carrier injection should be responsible for this tail distribution.

Published
2011
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47. The effects of memory cue and Memory Aid on prospective memory in older and younger adults

Author

M. S. Chen and C. N. Wang

Subjects
Time-Based Prospective Memory, medicine.medical_specialty, Hardware_MEMORYSTRUCTURES, Retrospective memory, Younger adults, Prospective memory, medicine, Cognition, Aging effect, Audiology, Psychology, Memory aid, Task (project management)
Abstract

Two experiments were conducted to examine the aging effect on prospective memory tasks and ongoing tasks. Experiment 1 was conducted to investigate the relationship between event-based prospective memory with different types of prospective cues and memory aid for both younger and older subjects. Experiment 2 was conducted to investigate the relationship between time-based prospective memory with different types of prospective cues and memory aid for younger and older subjects. Various prospective memory tasks and ongoing tasks were manipulated to examine the characteristics of the memory cues and memory aid to the target actions, the nature of the ongoing task, and age differences. The results showed that both performance of EBPM and TBPM was affected by the Memory Aid. The performance of older subjects improved with the use of memory aid compared to those not using memory aids. The performance of EBPM was also affected by memory cues, and a single memory cue was helpful for the older subjects.

Published
2010
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49. Fast frequency sweep analysis of RCS by accelerated asymptotic waveform evaluation method

Author

Xianliang Wu, Wei E. I. Sha, and M. S. Chen

Subjects
Signal processing, Computer simulation, Computer science, Linear system, Mathematical analysis, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, MathematicsofComputing_NUMERICALANALYSIS, Wavelet transform, Waveform, Method of moments (statistics), Sweep frequency response analysis, Sparse matrix
Abstract

The asymptotic waveform evaluation (AWE) technique is proposed with a preprocessing technique which is achieved by the arbitrarily dimensional fast lifting wavelet-like transform. With the new preprocessing technique, the sparse matrix equation in wavelet-domain is formed firstly. The wide band solution of this sparse linear system is obtained by application of AWE technique, and the actual induced surface current is computed by an inverse wavelet transform. Numerical simulation for differently shaped three dimensional objects has shown the efficiency of the present method.

Published
2010
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50. Adaptive Frequency sweep analysis for electromagnetic problems using the Thiele interpolating continued fractions

Author

Zhixiang Huang, Y. X. Sun, Xianliang Wu, Wei E. I. Sha, and M. S. Chen

Subjects
Mathematical optimization, Approximation theory, Adaptive algorithm, Computation, Computational electromagnetics, Applied mathematics, Method of moments (statistics), Impedance parameters, Sweep frequency response analysis, Interpolation, Mathematics
Abstract

A direct rational approximation method based on Thiele interpolating continued fractions theory is proposed for fast frequency sweep analysis of electromagnetic problems. And an adaptive algorithm is also formed. Compared with the conventional rational approximation method, the proposed method can get a rational approximation directly without a great number of matrix inverse computations and doesn't need to allocate much memory for high derivatives of the dense impedance matrix. Meanwhile, the computation of surface currents by continued fractions can be sped up as compared with the traditional rational approximation. Numerical simulations for broad band scattering analysis of different shaped objects are discussed to shown the effectiveness of the present method.

Published
2010
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