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Noyori-Ikariya type [(arene)RuCl(TsDPEN)] (TsDPEN, sulfonated diphenyl ethylenediamine) complexes are widely used C=O and C=N reduction catalysts that produce chiral alcohols and amines via a key ruthenium-hydride intermediate that determines the stereochemistry of the product. Whereas many details about the interactions of the pro-chiral substrate with the hydride complex and the nature of the hydrogen transfer from the latter to the former have been investigated over the past 25 years, the role of the stereochemical configuration at the stereogenic ruthenium center in the catalysis has not been elucidated so far. Using operando FlowNMR spectroscopy and nuclear Overhauser effect spectroscopy, we show the existence of two diastereomeric hydride complexes under reaction conditions, assign their absolute configurations in solution, and monitor their interconversion during transfer hydrogenation catalysis. Configurational analysis and multifunctional density functional theory (DFT) calculations show the λ-(R,R)SRu configured [(mesitylene)RuH(TsDPEN)] complex to be both thermodynamically and kinetically favored over its λ-(R,R)RRu isomer with the opposite configuration at the metal. Computational analysis of both diastereomeric catalytic manifolds show the major λ-(R,R)SRu configured [(mesitylene)RuH(TsDPEN)] complex to dominate asymmetric ketone reduction catalysis with the minor λ-(R,R)RRu [(mesitylene)RuH(TsDPEN)] stereoisomer being both less active and less enantioselective. These findings also hold true for a tethered catalyst derivative with a propyl linker between the arene and TsDPEN ligands and thus show enantioselective transfer hydrogenation catalysis with Noyori-Ikariya complexes to proceed via a lock-and-key mechanism.

In-situ NMR spectroscopic analysis of homogeneous reactions is an essential tool for mechanistic analysis in organic and organometallic chemistry. However, rapid non-equilibrium reactions, that are initiated by mixing, require specialized approaches. We report herein on a study of the factors that ensure quantitative results in a recently-developed technique for stopped-flow NMR spectroscopy. The influence of some of the key parameters on quantitation is studied by 19F NMR spectroscopic analysis of the kinetics and activation parameters for the base-catalyzed protodeboronation of highly-reactive polyfluorinated arylboronic acids, with half-lives as low as 0.1 seconds. The effects of spin relaxation, pre-magnetization, heat-transfer versus reaction enthalpy, and mixing-efficiency are analyzed in detail. We also compare and contrast choice of pulse angle, interscan delay, and use of pseudo real-time by interleaving, as means to achieve an optimal balance between temporal resolution and sensitivity.

Absolute cross sections for the addition of $s$- and $d$-wave neutrons to $^{14}$C and $^{14}$N have been determined simultaneously via the ($d$,$p$) reaction at 10 MeV/u. The difference between the neutron and proton separation energies, $\Delta S$, is around $-20$ MeV for the $^{14}$C$+$$n$ system and $+8$ MeV for $^{14}$N$+$$n$. The population of the $1s_{1/2}$ and $0d_{5/2}$ orbitals for both systems is reduced by a factor of approximately 0.5 compared to the independent single-particle model, or about 0.6 when compared to the shell model. This finding strongly contrasts with results deduced from intermediate-energy knockout reactions between similar nuclei on targets of $^{9}$Be and $^{12}$C. The simultaneous technique used removes many systematic uncertainties., Comment: 6 pages, 4 figures

CD4+CD25+Foxp3+T cell population is heterogenous and contains three major sub-groups. First, thymus derived T regulatory cells (tTreg) that are naïve/resting. Second, activated/memory Treg that are produced by activation of tTreg by antigen and cytokines. Third, effector lineage CD4+CD25+T cells generated from CD4+CD25-T cells’ activation by antigen to transiently express CD25 and Foxp3. We have shown that freshly isolated CD4+CD25+T cells are activated by specific alloantigen and IL-4, not IL-2, to Ts2 cells that express the IL-5 receptor alpha. Ts2 cells are more potent than naïve/resting tTreg in suppressing specific alloimmunity. Here, we showed rIL-5 promoted further activation of Ts2 cells to Th2-like Treg, that expressedfoxp3, irf4, gata3andil5. In vivo, we studied the effects of rIL-5 treatment on Lewis heart allograft survival in F344 rats. Host CD4+CD25+T cells were assessed by FACS, in mixed lymphocyte culture and by RT-PCR to examine mRNA of Ts2 or Th2-like Treg markers. rIL-5 treatment given 7 days after transplantation reduced the severity of rejection and all grafts survived ≥60d whereas sham treated rats fully rejected by day 31 (p+CD25+cells expressed moreIl5raand responded to specific donor Lewis but not self. Enriched CD4+CD25+cells from rIL-5 treated rats with allografts surviving >60 days proliferated to specific donor only when rIL-5 was present and did not proliferate to self or third party. These cells had more mRNA for molecules expressed by Th2-like Treg including Irf4, gata3andIl5.These findings were consistent with IL-5 treatment preventing rejection by activation of Ts2 cells and Th2-like Treg.

Recurring outbreaks of crown-of-thorns starfish (COTS) severely damage healthy corals in the Western Pacific Ocean. To determine the source of outbreaking COTS larvae and their dispersal routes across the Western Pacific, complete mitochondrial genomes were sequenced from 243 individuals collected in 11 reef regions. Our results indicate that Pacific COTS comprise two major clades, an East-Central Pacific clade (ECP-C) and a Pan-Pacific clade (PP-C). The ECP-C consists of COTS from French Polynesia (FP), Fiji, Vanuatu and the Great Barrier Reef (GBR), and does not appear prone to outbreaks. In contrast, the PP-C, which repeatedly spawns outbreaks, is a large clade comprising COTS from FP, Fiji, Vanuatu, GBR, Papua New Guinea, Vietnam, the Philippines, Japan, Micronesia, and the Marshall Islands. Given the nature of Pacific Ocean currents, the vast area encompassing FP, Fiji, Vanuatu, and the GBR likely supplies larvae for repeated outbreaks, exacerbated by anthropogenic environmental changes, such as eutrophication.

Hyperpolarization techniques can enormously enhance the NMR signal thus allowing the exploitation of hyperpolarized substrates for in-vivo MRI applications. The short lifetime of hyperpolarized spin order poses significant limitations in such applications. Spin order storage can be prolonged through the use of long-lived spin states. Additionally, the storage of spin polarization–either in the form of longitudinal or singlet order–can be prolonged in low viscosity solutions. Here, we report the use of low viscosity liquid-CO2 solutions to store nuclear spin polarization in the form of longitudinal and singlet order for extended periods. Our results demonstrate that this storage time can be considerably sustained in liquid-CO2 solutions in comparison to other low viscosity solvents, opening up the possibility of new, exciting storage experiments in the future.

Type-I x-ray bursts can reveal the properties of an accreting neutron star system when compared with astrophysics model calculations. However, model results are sensitive to a handful of uncertain nuclear reaction rates, such as ^{22}Mg(α,p). We report the first direct measurement of ^{22}Mg(α,p), performed with the Active Target Time Projection Chamber. The corresponding astrophysical reaction rate is orders of magnitude larger than determined from a previous indirect measurement in a broad temperature range. Our new measurement suggests a less-compact neutron star in the source GS1826-24.

Proton capture on the excited isomeric state of ^{26}Al strongly influences the abundance of ^{26}Mg ejected in explosive astronomical events and, as such, plays a critical role in determining the initial content of radiogenic ^{26}Al in presolar grains. This reaction also affects the temperature range for thermal equilibrium between the ground and isomeric levels. We present a novel technique, which exploits the isospin symmetry of the nuclear force, to address the long-standing challenge of determining proton-capture rates on excited nuclear levels. Such a technique has in-built tests that strongly support its veracity and, for the first time, we have experimentally constrained the strengths of resonances that dominate the astrophysical ^{26m}Al(p,γ)^{27}Si reaction. These constraints demonstrate that the rate is at least a factor ∼8 lower than previously expected, indicating an increase in the stellar production of ^{26}Mg and a possible need to reinvestigate sensitivity studies involving the thermal equilibration of ^{26}Al.

We present a design for a temperature-controlled sample shuttle for use in NMR measurements at variable magnetic field strength. Accurate temperature control was achieved using a mixture of water-ethylene glycol as a heat transfer fluid, reducing temperature gradients across the sample to < 0.05 °C and minimising convection. Using the sample shuttle, we show how the longitudinal (T 1) and singlet order (T S) relaxation time constants were measured for two molecules capable of supporting long-lived states, with new record lifetimes observed at low field and above ambient temperatures.

Nuclear reactions play a key role in the framework of the Big Bang Nucleosynthesis. A network of 12 principal reactions has been identified as the main path that drove the elemental nucleosynthesis in the first 20 min of the history of the Universe. Among them an important role is played by neutron-induced reactions, which, from an experimental point of view, are usually a difficult task to be measured directly. Nevertheless big efforts in the last decades have led to a better understanding of their role in the primordial nucleosynthesis network. In this work we apply the Trojan Horse Method to extract the cross section at astrophysical energies for the $$^3\text {He}$$ (n,p) $$^3\text {H}$$ reaction after a detailed study of the $$^2\hbox {H}$$ ( $$^3\text {He}$$ ,pt)H three-body process. Data extracted from the present measurement are compared with other published sets.

Quasi-elastic scattering measurements have been performed using 16O and 24Mg projectiles off 90Zr at energies around the Coulomb barrier. Experimental data have been analyzed in the framework of coupled channels (CC) calculations using the code CCFULL. The quasi-elastic scattering excitation function and derived barrier distribution for 16O + 90Zr reaction are well reproduced by the CC calculations using the vibrational coupling strengths for 90Zr reported in the literature. Using these vibrational coupling strengths, a Bayesian analysis is carried out for 24Mg + 90Zr reaction. The β 2 and β 4 values for 24Mg are determined to be + 0.43 ± 0.02 and − 0.11 ± 0.02 , respectively. The β 2 parameter determined in the present work is in good agreement with results obtained using inelastic scattering probes. The hexadecapole deformation of 24Mg has been measured very precisely for the first time. Present results establish that quasi-elastic scattering could provide a useful probe to determine the ground state deformation of atomic nuclei.

In the network of reactions present in the Big Bang nucleosynthesis, the 3He(n, p)3H has an important role which impacts the final 7Li abundance. The Trojan Horse Method (THM) has been applied to the 3He(d, pt)H reaction in order to extract the astrophysical S(E)-factor of the 3He(n, p)3H in the Gamow energy range. The experiment will be described in the present work together with the first preliminary results.

Certain astrophysical environments such as thermonuclear outbursts on accreting neutron stars (Type-I X-ray bursts) are hot enough to allow for breakout from the Hot CNO hydrogen burning cycles to the rapid proton capture (rp) process. An important breakout reaction sequence is 15O(α,γ)19Ne(p,γ)20Na and the 19Ne(p,γ)20Na reaction rate is expected to be dominated by a single resonance at 457 keV above the proton threshold in 20Na. The resonance strength and, hence, reaction rate depends strongly on whether this 20Na state at an excitation energy of 2647 keV has spin and parity of 1 + or 3 + . Previous 20Mg ( J π = 0 + ) β + decay experiments have relied almost entirely on searches for β-delayed proton emission from this resonance in 20Na to limit the log ft value and, hence, J π . However there is a non-negligible γ-ray branch expected that must also be limited experimentally to determine the log ft value and constrain J π . We have measured the β-delayed γ decay of 20Mg to complement previous β-delayed proton decay work and provide the first complete limit based on all energetically allowed decay channels through the 2647 keV state. Our limit confirms that a 1 + assignment for this state is highly unlikely.

GODDESS is a coupling of the charged-particle detection system ORRUBA to the gamma-ray detector array Gammasphere. This coupling has been developed in order to facilitate the high-resolution measurement of direct reactions in normal and inverse kinematics with stable and radioactive beams. GODDESS has been commissioned using a beam of 134 Xe at 10 MeV/A, in a campaign of stable beam measurements. The measurement demonstrates the capabilities of GODDESS under radioactive beam conditions, and provides the first data on the single-neutron states in 135 Xe, including previously unobserved states based on the orbitals above the N=82 shell closure.

The 14O(α,p)17F reaction is an important trigger reaction to the α-p process in X-ray bursts. The most stringent experimental constraints on its astrophysical rate come from measurements of the time-inverse reaction, 17F(p,α)14O. Previous studies of this inverse reaction have sufficiently characterized the high-energy dependence of the cross section but there are still significant uncertainties at lower energies. A new measurement of the 17F(p,α)14O cross section is underway at the Twin Solenoid (TwinSol) facility at the University of Notre Dame using an in-flight secondary 17F beam. The initial results are promising but improvements are needed to complete the measurement. The initial data and plans for an improved measurement are presented in this manuscript.

Electromagnetic observables are able to give insight into collective and emergent features in nuclei, including nuclear clustering. These observables also provide strong constraints for ab initio theory, but comparison of these observables between theory and experiment can be difficult due to the lack of convergence for relevant calculated values, such as $E2$ transition strengths. By comparing the ratios of $E2$ transition strengths for mirror transitions, we find that a wide range of ab initio calculations give robust and consistent predictions for this ratio. To experimentally test the validity of these ab initio predictions, we performed a Coulomb excitation experiment to measure the $B(E2;3/{2}^{\ensuremath{-}}\ensuremath{\rightarrow}1/{2}^{\ensuremath{-}})$ transition strength in $^{7}\mathrm{Be}$ for the first time. A $B(E2;3/{2}^{\ensuremath{-}}\ensuremath{\rightarrow}1/{2}^{\ensuremath{-}})$ value of $26{(6)}_{\mathrm{stat}}{(3)}_{\mathrm{syst}}\phantom{\rule{0.16em}{0ex}}{e}^{2}{\mathrm{fm}}^{4}$ was deduced from the measured Coulomb excitation cross section. This result is used with the experimentally known $^{7}\mathrm{Li}\phantom{\rule{4pt}{0ex}}B(E2;3/{2}^{\ensuremath{-}}\ensuremath{\rightarrow}1/{2}^{\ensuremath{-}})$ value to provide an experimental ratio to compare with the ab initio predictions. Our experimental value is consistent with the theoretical ratios within $1\ensuremath{\sigma}$ uncertainty, giving experimental support for the value of these ratios. Further work in both theory and experiment can give insight into the robustness of these ratios and their physical meaning.

Background: The $^{15}\mathrm{O}(\ensuremath{\alpha},\ensuremath{\gamma})^{19}\mathrm{Ne}$ bottleneck reaction in Type I x-ray bursts is the most important thermonuclear reaction rate to constrain experimentally, to improve the accuracy of burst light-curve simulations. A proposed technique to determine the thermonuclear rate of this reaction employs the $^{20}\mathrm{Mg}(\ensuremath{\beta}p\ensuremath{\alpha})^{15}\mathrm{O}$ decay sequence. The key $^{15}\mathrm{O}(\ensuremath{\alpha},\ensuremath{\gamma})^{19}\mathrm{Ne}$ resonance at an excitation of 4.03 MeV is now known to be fed in $^{20}\mathrm{Mg}(\ensuremath{\beta}p\ensuremath{\gamma})^{19}\mathrm{Ne}$; however, the energies of the protons feeding the 4.03 MeV state are unknown. Knowledge of the proton energies will facilitate future $^{20}\mathrm{Mg}(\ensuremath{\beta}p\ensuremath{\alpha})^{15}\mathrm{O}$ measurements.Purpose: To determine the energy of the proton transition feeding the 4.03 MeV state in $^{19}\mathrm{Ne}$.Method: A fast beam of $^{20}\mathrm{Mg}$ was implanted into a plastic scintillator, which was used to detect $\ensuremath{\beta}$ particles. 16 high purity germanium detectors were used to detect $\ensuremath{\gamma}$ rays emitted following $\ensuremath{\beta}p$ decay. A Monte Carlo method was used to simulate the Doppler broadening of $^{19}\mathrm{Ne}\phantom{\rule{4pt}{0ex}}\ensuremath{\gamma}$-ray lines and compare to the experimental data.Results: The center of mass energy between the proton and $^{19}\mathrm{Ne}$, feeding the 4.03 MeV state, is measured to be $1.21{}_{\ensuremath{-}0.22}^{+0.25}\phantom{\rule{0.16em}{0ex}}\mathrm{MeV}$, corresponding to a $^{20}\mathrm{Na}$ excitation energy of $7.44{}_{\ensuremath{-}0.22}^{+0.25}\phantom{\rule{0.16em}{0ex}}\mathrm{MeV}$. Absolute feeding intensities and $\ensuremath{\gamma}$-decay branching ratios of $^{19}\mathrm{Ne}$ states were determined including the 1615 keV state, which has not been observed before in this decay. A new $\ensuremath{\gamma}$ decay branch from the 1536 keV state in $^{19}\mathrm{Ne}$ to the ground state is reported. The lifetime of the 1507 keV state in $^{19}\mathrm{Ne}$ is measured to be $4.3{}_{\ensuremath{-}1.1}^{+1.3}$ ps resolving discrepancies in the literature. Conflicting $^{20}\mathrm{Mg}(\ensuremath{\beta}p$) decay schemes in published literature are clarified.Conclusions: The utility of this Doppler broadening technique to provide information on $\ensuremath{\beta}$-delayed nucleon emission and excited-state lifetimes has been further demonstrated. In particular, knowledge of the proton energies feeding the 4.03 MeV $^{19}\mathrm{Ne}$ state in $^{20}\mathrm{Mg}\phantom{\rule{4pt}{0ex}}\ensuremath{\beta}$ decay will facilitate future measurements of the $\ensuremath{\alpha}$-particle branching ratio.

Proper understanding of the stellar nucleosynthesis processes requires information on a variety of capture reaction cross sections. Since these cross sections are typically very low, they require efficient measurement techniques. The High Efficiency Total Absorption Spectrometer (HECTOR) was designed to measure capture cross sections relevant for astrophysical processes. HECTOR is a $ \gamma$ -summing detector comprised of 16 separate NaI(Tl) segments. The detector design is presented, as well as a detailed study of the detector's summing efficiency and analysis procedure. The results of the commissioning of HECTOR are presented. The resonance strengths of the well-known resonances in the 27Al $ (\mathrm{p},\gamma)$28Si reaction measured with HECTOR are compared with the literature values.

The $^{15}$O($\alpha$,$\gamma$)$^{19}$Ne reaction is responsible for breakout from the hot CNO cycle in Type I x-ray bursts. Understanding the properties of resonances between $E_x = 4$ and 5 MeV in $^{19}$Ne is crucial in the calculation of this reaction rate. The spins and parities of these states are well known, with the exception of the 4.14- and 4.20-MeV states, which have adopted spin-parities of 9/2$^-$ and 7/2$^-$, respectively. Gamma-ray transitions from these states were studied using triton-$\gamma$-$\gamma$ coincidences from the $^{19}$F($^{3}$He,$t\gamma$)$^{19}$Ne reaction measured with GODDESS (Gammasphere ORRUBA Dual Detectors for Experimental Structure Studies) at Argonne National Laboratory. The observed transitions from the 4.14- and 4.20-MeV states provide strong evidence that the $J^\pi$ values are actually 7/2$^-$ and 9/2$^-$, respectively. These assignments are consistent with the values in the $^{19}$F mirror nucleus and in contrast to previously accepted assignments.

We report a new precision half-life measurement of $^{20}\mathrm{F}$, performed using the $\ensuremath{\beta}$-counting station of the University of Notre Dame's Nuclear Science Laboratory. The measured half-life of $11.0160{(41)}_{\text{stat}}{(155)}_{\text{sys}}$ s resulting from this work will help resolve the longstanding discrepancy between two earlier sets of high-precision half-life measurements.

A direct test of nova explosion models comes from the observation of γ rays created in the decay of radioactive isotopes produced in the nova. One such isotope, 18F, is believed to be the main source of observable γ rays at and below 511 keV. The main destruction mechanism of 18F is thought to be the 18F(p,α)15O reaction, and uncertainties in the reaction rate arise from uncertainties in the energies, spins, and parities of the nuclear levels in 19Ne above the 18F+p threshold. To measure the properties of these levels, the 19F(3He,t)19Ne∗(γ) reaction was studied at Argonne National Laboratory and the Nuclear Science Laboratory at the University of Notre Dame.A direct test of nova explosion models comes from the observation of γ rays created in the decay of radioactive isotopes produced in the nova. One such isotope, 18F, is believed to be the main source of observable γ rays at and below 511 keV. The main destruction mechanism of 18F is thought to be the 18F(p,α)15O reaction, and uncertainties in the reaction rate arise from uncertainties in the energies, spins, and parities of the nuclear levels in 19Ne above the 18F+p threshold. To measure the properties of these levels, the 19F(3He,t)19Ne∗(γ) reaction was studied at Argonne National Laboratory and the Nuclear Science Laboratory at the University of Notre Dame.

Much effort has been made to understand the origins of 18F in novae. Due to its relatively long half-life (~2 hours), 18F can survive until the nova envelope is transparent, and therefore can provide a sensitive diagnostic of nova nucleosynthesis. It is likely produced through the beta decay of 18Ne, which is itself produced (primarily) through the 17F(p,γ) reaction. Understanding the direct capture contribution to the 17F(p,γ) reaction is important to accurately calculate it. As such, the proton spectroscopic strengths of low-lying states in 18Ne are needed. At the University of Notre Dame a measurement of the 17F(d,n) reaction has been performed using a beam produced by the TwinSol low energy radioactive beam facility. Preliminary data analysis is presented.

In the network of reactions present in the Big Bang nucleosynthesis, the 3He(n, p)3H reaction has an important role which impacts the final 7Li abundance. The Trojan Horse Method (THM) has been applied to the 3He(d, pt)H reaction in order to extract the astrophysical S(E)-factor of the 3He(n, p)3H reaction in the Gamow energy range. The experiment will be described in the present work together with the first preliminary results.

Helical spectrometers, such as the HELIOS device at Argonne National Laboratory, have proven to be a powerful tool for the study of nuclear spectroscopy (Lighthall, 2010). However, due to the expense in procuring a large bohr solenoid, relatively few of these devices exist. However, at the University of Notre Dame, TwinSol , is composed of two such magnets. The availability of intense light-ion beams from the Notre Dame Nuclear Science Laboratory (NSL) in combination with a large-bore superconducting solenoids provides an excellent opportunity to develop a new solenoid spectrometer at the University of Notre Dame, one optimized for measurements in normal kinematics.

Detection of nuclear-decay γ rays provides a sensitive thermometer of nova nucleosynthesis. The most intense γ-ray flux is thought to be annihilation radiation from the β^{+} decay of ^{18}F, which is destroyed prior to decay by the ^{18}F(p,α)^{15}O reaction. Estimates of ^{18}F production had been uncertain, however, because key near-threshold levels in the compound nucleus, ^{19}Ne, had yet to be identified. We report the first measurement of the ^{19}F(^{3}He,tγ)^{19}Ne reaction, in which the placement of two long-sought 3/2^{+} levels is suggested via triton-γ-γ coincidences. The precise determination of their resonance energies reduces the upper limit of the rate by a factor of 1.5-17 at nova temperatures and reduces the average uncertainty on the nova detection probability by a factor of 2.1.

Background: The precise determination of the $\mathcal{F}t$ value in $T=1/2$ mixed mirror decays is an important avenue for testing the standard model of the electroweak interaction through the determination of ${V}_{ud}$ in nuclear $\ensuremath{\beta}$ decays. $^{11}\mathrm{C}$ is an interesting case, as its low mass and small ${Q}_{EC}$ value make it particularly sensitive to violations of the conserved vector current hypothesis. The present dominant source of uncertainty in the $^{11}\mathrm{C}\phantom{\rule{4pt}{0ex}}\mathcal{F}t$ value is the half-life.Purpose: A high-precision measurement of the $^{11}\mathrm{C}$ half-life was performed, and a new world average half-life was calculated.Method: $^{11}\mathrm{C}$ was created by transfer reactions and separated using the TwinSol facility at the Nuclear Science Laboratory at the University of Notre Dame. It was then implanted into a tantalum foil, and $\ensuremath{\beta}$ counting was used to determine the half-life.Results: The new half-life, ${t}_{1/2}=1220.27(26)$ s, is consistent with the previous values but significantly more precise. A new world average was calculated, ${t}_{1/2}^{\text{world}}=1220.41(32)$ s, and a new estimate for the Gamow-Teller to Fermi mixing ratio $\ensuremath{\rho}$ is presented along with standard model correlation parameters.Conclusions: The new $^{11}\mathrm{C}$ world average half-life allows the calculation of a $\mathcal{F}{t}^{\text{mirror}}$ value that is now the most precise value for all superallowed mixed mirror transitions. This gives a strong impetus for an experimental determination of $\ensuremath{\rho}$, to allow for the determination of ${V}_{ud}$ from this decay.

Ab-initio calculations have been able to reproduce emergent phenomena such as the formation of clusters in nuclei, a prominent feature in light nuclei. A number of ab-initio methods have made predictions for the B(E2; 3/2− → 1/2−) transition strength in the radioactive nucleus 7Be where a prominent α-3 He structure is expected. In order to test and guide these ab-inito methods, we have performed a Coulomb excitation experiment to measure the B(E2; 3/2− → 1/2−) in 7Be. Our current results point to the importance of reproducing cluster features in our nuclear models.Ab-initio calculations have been able to reproduce emergent phenomena such as the formation of clusters in nuclei, a prominent feature in light nuclei. A number of ab-initio methods have made predictions for the B(E2; 3/2− → 1/2−) transition strength in the radioactive nucleus 7Be where a prominent α-3 He structure is expected. In order to test and guide these ab-inito methods, we have performed a Coulomb excitation experiment to measure the B(E2; 3/2− → 1/2−) in 7Be. Our current results point to the importance of reproducing cluster features in our nuclear models.

Transfer reactions have provided exciting opportunities to study the structure of exotic nuclei and are often used to inform studies relating to nucleosynthesis and applications. In order to benefit from these reactions and their application to rare ion beams (RIBs) it is necessary to develop the tools and techniques to perform and analyze the data from reactions performed in inverse kinematics, that is with targets of light nuclei and heavier beams. We are continuing to expand the transfer reaction toolbox in preparation for the next generation of facilities, such as the Facility for Rare Ion Beams (FRIB), which is scheduled for completion in 2022. An important step in this process is to perform the (d,n) reaction in inverse kinematics, with analyses that include Q-value spectra and differential cross sections. In this way, proton-transfer reactions can be placed on the same level as the more commonly used neutron-transfer reactions, such as (d,p), (9Be,8Be), and (13C,12C). Here we present an overview of the techniques used in (d,p) and (d,n), and some recent data from (d,n) reactions in inverse kinematics using stable beams of 12C and 16O., 9 pages, 4 figures, presented at the XXXV Mazurian Lakes Conference on Physics, Piaski, Poland

TwinSol , a pair of coupled, superconducting solenoids, was one of the first devices capable of producing beams of radioactive nuclei at energies near the Coulomb barrier. A primary beam from University of Notre Dame (UND) tandem accelerator is used to bombard a primary target producing a secondary beam in flight. TwinSol is used to gather, separate, and focus the recoils. Since it was commissioned at the UND in 1997, at least 58 publications have reported data from its use and there have been hundreds of collaborators from many different countries that use this device. Currently, plans are in place at the UND to provide several upgrades to TwinSol , including a multi-cell gas production target and the possible addition of a third solenoid. Upgrades currently in progress will be discussed along with future plans.

We demonstrate how FlowNMR spectroscopy can readily be applied to investigate photochemical reactions that require sustained input of light and air to yield mechanistic insight under realistic conditions. The Eosin Y mediated photo-oxidation of N-allylbenzylamine is shown to produce imines as primary reaction products from which undesired aldehydes form after longer reaction times. Facile variation of reaction conditions during the reaction in flow allows for probe experiments that give information about the mode of action of the photocatalyst.

The $^{15}\mathrm{O}(\ensuremath{\alpha},\ensuremath{\gamma})^{19}\mathrm{Ne}$ reaction is expected to trigger the initial path for breakout from the CNO hydrogen-burning cycles to the rapid proton capture $(rp)$ process in type I x-ray bursts on accreting neutron stars. The thermonuclear reaction rate has a major impact on models of type I x-ray burst observables and it depends on the small $\ensuremath{\alpha}$-particle branching ratio, ${\mathrm{\ensuremath{\Gamma}}}_{\ensuremath{\alpha}}/\mathrm{\ensuremath{\Gamma}}$, of the 4.03 MeV state in $^{19}\mathrm{Ne}$. Attempts to measure ${\mathrm{\ensuremath{\Gamma}}}_{\ensuremath{\alpha}}/\mathrm{\ensuremath{\Gamma}}$ by populating the 4.03 MeV state using nuclear reactions have only led to strong upper limits. In the present work, we report the first experimental evidence that the 4.03 MeV $^{19}\mathrm{Ne}$ state is populated in $^{20}\mathrm{Mg} \ensuremath{\beta}$-delayed proton emission. This new channel has the potential to provide the necessary sensitivity to detect a finite value of ${\mathrm{\ensuremath{\Gamma}}}_{\ensuremath{\alpha}}/\mathrm{\ensuremath{\Gamma}}$.

A new precision half-life measurement of $^{25}\mathrm{Al}$ was conducted using the TwinSol $\ensuremath{\beta}$-counting station at the University of Notre Dame. The new measured value of ${t}_{1/2}^{\mathrm{new}}=7.1657(24)$ s is in good agreement with the most recent measurement, while being 3 times more precise. Using these new measurements, an evaluation of the $^{25}\mathrm{Al}$ half-life has been performed, leading to an average half-life of ${t}_{1/2}^{\mathrm{world}}=7.1665(26)$ s, which is 5 times more precise than it's predecessor and has a more satisfactory Birge ratio of 1.1. To aid in future measurements of correlation parameters, a new Fermi to Gamow-Teller mixing ratio $\ensuremath{\rho}$ and correlation parameters for this mixed transition have been calculated assuming the standard model validity using the new world half-life.

When a neutron star accretes hydrogen and helium from the outer layers of its companion star, thermonuclear burning enables the α p-process as a break out mechanism from the hot CNO cycle. Model calculations predict ( α , p) reaction rates significantly affect both the light curves and elemental abundances in the burst ashes. The Jet Experiments in Nuclear Structure and Astrophysics (JENSA) gas jet target enables the direct measurement of previously inaccessible ( α ,p) reactions with radioactive beams provided by the rare isotope re-accelerator ReA3 at the National Superconducting Cyclotron Laboratory (NSCL), USA. JENSA is going to be the main target for the Recoil Separator for Capture Reactions (SECAR) at the Facility for Rare Isotope Beams (FRIB). Commissioning of JENSA and first experiments at Oak Ridge National Laboratory (ORNL) showed a highly localized, pure gas target with a density of ∼10 19 atoms per square centimeter. Preliminary results are presented from the first direct cross section measurement of the 34 Ar( α , p) 37 K reaction at NSCL.

FlowNMR spectroscopy is an excellent technique for non-invasive real-time reaction monitoring under relevant conditions that avoids many of the limitations that bedevil other reaction monitoring techniques. With the recent commercial availability of FlowNMR hard- and software solutions for high resolution spectrometers it is enjoying increased popularity in both academia and industry. We present an account on practical aspects of high field multi-nuclear FlowNMR for reaction monitoring including apparatus design, flow effects, acquisition parameters and data treatment, which are important to consider if accurate kinetic data are to be obtained from FlowNMR experiments. Flow effects on NMR peak areas are particularly important as they can lead to large quantification errors if overlooked, but can easily be corrected for and even used to increase temporal resolution with suitably adjusted instrument settings.

An unexpected breakdown of the isobaric multiplet mass equation in the $A=20$, $T=2$ quintet was recently reported, presenting a challenge to modern theories of nuclear structure. In the present work, the excitation energy of the lowest $T = 2$ state in $^{20}$Na has been measured to be $6498.4 \pm 0.2_{\textrm{stat}} \pm 0.4_{\textrm{syst}}$ keV by using the superallowed $0^+ \rightarrow 0^+$ beta decay of $^{20}$Mg to access it and an array of high-purity germanium detectors to detect its $\gamma$-ray deexcitation. This value differs by 27 keV (1.9 standard deviations) from the recommended value of $6525 \pm 14$ keV and is a factor of 28 more precise. The isobaric multiplet mass equation is shown to be revalidated when the new value is adopted., Comment: 5 pages, 5 figures

The study of low-energy reactions with radioactive-ion beams has been greatly enhanced by the recent use of active-target detectors, which have high efficiency and low thresholds to detect low-energy charged-particle decays. Both of these features have been used in experiments with the Prototype Active-Target Time-Projection Chamber to study α -cluster structure in unstable nuclei and 3-body charged-particle decays after implantation. Predicted α -cluster structures in 14 C were probed using resonant α scattering and the nature of the 3- α breakup of the 0 2 + Hoyle state in 12 C after the beta decay of 12 N and 12 B was studied. These experiments used in-flight radioactive-ion beams that were produced using the dual superconducting solenoid magnets TwinSol at the University of Notre Dame. Preliminary results from these experiments as well as the development of future radioactive beams to be used in conjunction with the PAT-TPC are presented.

Preliminary results for the elastic scattering of the Super-Borromean nucleus10C on27Al are presented, at E lab = 29 MeV. Taking the Sao Paulo potential as the bare potential, possible polarization potentials are investigated by adding a volume and a surface complex term to account for fusion and direct couplings, respectively. Besides an imaginary short-range potential to simulate the bulk of fusion, the best-fit polarization potential turns out to be real and has the effect of shifting the barrier radius up by 0.6 fm, thus suggesting a fusion enhancement.

Objective To determine the relationship between persistently raised anticardiolipin antibody (aCL) levels and neuropsychological performance in patients with systemic lupus erythematosus (SLE). Methods Forty-five patients with SLE underwent a detailed neuropsychological assessment on 2 occasions 12–18 months apart. Serum samples stored since the time of previous assessments as well as samples obtained 6 months to 2 years before the first neuropsychological assessment were tested for IgG aCL levels. Patients were divided into 4 groups according to the number of times their aCL levels were elevated (never, once, twice, 3 times). A wide-ranging battery of new neuropsychological tests was utilized, and the results were compared with double-stranded DNA (dsDNA) antibody levels, C3 levels, and results of magnetic resonance imaging (MRI). Results Analysis of variance revealed that the group with persistently elevated aCL levels performed less well than the other groups. At the first neuropsychological assessment, poorer performance by this group was noted for letter cancellation (P = 0.02), trail making task B (P = 0.04), and digit span (P = 0.03). At the second assessment, letter cancellation (P = 0.01), trail making task A (P = 0.03), trail making task B (P = 0.01), word fluency (P = 0.01), and reaction time (P = 0.05) were impaired. In contrast, no significant differences in neuropsychological test results were identified with respect to DNA antibody or C3 levels. MRI abnormalities were associated with both persistent elevation of aCL levels and low C3 levels. Conclusion Levels of IgG aCL that were persistently elevated over a 2–3-year period (as opposed to never or occasionally elevated) were associated with significantly poorer performance in cognitive function by patients with SLE. Tasks requiring speed of attention and concentration appear to be particularly affected.

As part of a bioassay approach to investigate ovarian development and function, primary cell cultures were derived from Penaeus monodon ovaries at various stages of maturation. These cultures were established in modified Grace's or modified 2x L-15 media. Various supplements including growth factors, vitamins and minerals were trailed. Four morphologically different types of cells (epithelioid, fibroblastic, rounded, and epithelioid with large nuclei) were maintained for up to 17 months. Epithelioid cells grew best in modified Grace's medium but were generally short-lived (less than two months). Fibroblast-like cells formed confluent monolayers in modified 2x L-15 medium, were passaged three times and survived for 17 months. In other cultures, millions of rounded cells migrated from tissue. They survived for prolonged periods (up to ten months), either loosely attached to the flask or suspended in the medium. A change in dominant cell type from fibroblastic to epithelioid was observed in some cultures after three or nine months incubation. These epithelioid cells which had very large nuclei, grew to confluence but could not be sub-cultured. It is noteworthy that the rounded cells and the epithelioid cells with the large nuclei both produced vitellogenin in protein-free media.