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A wrist joint in upper limb prostheses significantly increases its handling capacity. However, current prostheses cannot reproduce the ability of torque combined with the volume and weight of the human wrist. Consequently, they do not provide high efficiency in handling and generate user dissatisfaction. In this context, this study aims to optimal design a wrist supination and pronation brake to improve the handling capacity of an upper limb prosthesis. The wrist actuator consists of an EC motor and harmonic drive parallel with a magnetorheological brake. The brake guarantees a fast response time, low energy consumption, controllability, and small dimensions. A particle swarm algorithm is applied to optimize design variables to minimize mass and energy consumption. As a result, the brake provided resistive torque of 7.4 N.m with dimensions close to a healthy member and weighing 0.1972 kg. Finally, a finite element analysis confirmed a satisfactory magnetic flux for the magnetorheological brake operating conditions. The designed brake addressed all the desired characteristics and is suitable to integrate the forearm prosthesis with wrist rotation.

In this paper we are considering a third-order three-point equation with nonhomogeneous conditions in the boundary. Using Krasnoselskii’s Theorem and Leray-Schauder Alternative we provide existence results of positive solutions for this problem. Nontrivials examples are given and a numerical method is introduced.

The aim of the present study was to examine the vaccine immune response in ewes supplemented with Bacillus toyonensis BCT-7112Ewes were vaccinated with 200 µg of rETX adjuvanted with 10% aluminium hydroxide. The treat group was orally supplemented with B. toyonensis BCT-7112We conclude that a 5 days of supplementation with B. toyonensis BCT-7112These findings open a new perspective in the utilization of B. toyonensis BCT-7112

The use of natural enemies represents an important strategy in programs of Integrated Pest Management (IPM). Asopinae predators are reared with alternative prey, but supplementary plant may enhance the fecundity and longevity of their females. The objective of this research was to evaluate the development and reproduction of the predator Brontocoris tabidus Signoret, 1852 (Heteroptera: Pentatomidae) fed with Tenebrio molitor L., 1785 (Coleoptera: Tenebrionidae) pupae in a Eucalyptus grandis Hill ex Maiden (Myrtaceae) plant in the field. The duration and survival of the nymphal stage of B. tabidus were 32.07 ± 8.95 days and 77.00 ± 0.42%, respectively with 15.55 ± 8.19 egg masses, 603.00 ± 379.20 eggs and 387.45 ± 291.40 nymphs per female of this predator while longevity of its males and females was 119.80 ± 32.80 and 160.20 ± 42.13 days, respectively. Better results with E. grandis plant in the field and the fact that B. tabidus will be adapted at release time show that this predator should be reared in these conditions.

The aim of this study was to obtain new vehicles for topical formulations based on the mixture of hydrogels (aqueous systems) with oleogels (lipophilic systems). Several formulations were prepared using different oleogels mixed with polyacrylic acid hydrogel without addition of other ingredients. The moisturizing effect of the bigels was assessed along with the hydrogel and oleogels used in their preparation by carrying out an in vivo study with 14 healthy volunteers. Corneometer measurements were taken each hour during a five-hour period after product's application. Stability tests (storage at 20 and 40 degrees C for six months) and mechanical characterization were also carried out. Stability tests showed no modifications of the textural properties and appearance over a six-month period at 20 degrees C. At accelerated conditions, modifications of colour and textural properties were detected after six months' storage. While retaining the mechanical and sensory properties of the hydrogel, the bigels showed simultaneously an enhanced moisturizing effect, making them promising candidates for topical formulations.

Diffuse reflectance and laser-induced techniques were used to access photochemical and photophysical processes of benzil in solid supports, namely p-tert-butylcalix[n]arenes with n = 4, 6, and 8. A comparative study was performed using these results and those obtained with another electronically inert support, silicalite, which is a hydrophobic zeolite. In the latter substrate, ground-state benzil has the two carbonyl groups in an s-trans planar conformation while in the calixarenes a distribution of conformers exists, largely dominated by skew conformations where the carbonyl groups are twisted one to the other. In all substrates, room-temperature phosphorescence was obtained in air-equilibrated samples. The decay times vary greatly and the largest lifetime was obtained for benzil/p-tert-butylcalix[6]arene, showing that this host cavity well accommodates benzil, enhancing its room-temperature phosphorescence. p-tert-Butylcalix[6] and [8]arene molecules provide larger hydrophobic cavities than silicalite, and inclusion complexes are formed with these hosts and benzil as guest; p-tert-butylcalix[4]arene does not include benzil. This probe is deposited outside the calix[41 cavity, in the form of microcrystals. Triplet-triplet absorption of benzil was detected in all cases and is predominant in the silicalite channel inclusion case. Benzil ketyl radical formation occurs with inclusion in calix[6]arene and calix[8]arene. In the three cases, benzoyl radical was detected at long times (in the millisecond time scale). Product analysis and identification clearly show that the main detected degradation photoproducts in all substrates are benzoyl radical derivatives. Calix[6] and [8]arenes are able to supply hydrogen atoms that allow also another reaction, the reduction to benzoin through benzil ketyl radical formation.

Diffuse reflectance and laser-induced techniques were used to access photochemical and photophysical processes in solid phases, namely calix[ n ]arenes ( n is the number of phenolic units in the ring), organic substances which are capable of forming inclusion complexes with several neutral organic substances and metal ions. We have used p - tert -butylcalix[4], p - tert -butylcalix[6] and p - tert -butylcalix[8]arenes as solid matrixes and benzophenone as probe. A comparative study is presented here, mainly using the results obtained with the calix[6]arene as host and those obtained with two other electronically inert supports: microcrystalline cellulose and silicalite, a hydrophobic zeolite. In all substrates, room temperature phosphorescence was obtained in air equilibrated samples. The decay times vary greatly and the largest lifetime was obtained for silicalite, where benzophenone is included into hydrophobic channels. Calix[6]arene and cellulose provide full protection against oxygen quenching while silicalite only protects the guest molecule partially. Calixarene molecules provide larger hydrophobic cavities than silicalite and also a better selectivity towards the guest size. This selectivity does not exist in the microcrystalline cellulose case. FTIR absorption spectra show that the distortion from planarity in the benzophenone molecule is larger in silicalite than in calix[6]arene, while in cellulose the distortion is slight. In spite of this, benzophenone exhibits the highest phosphorescence emission quantum yield in the case of silicalite. Benzophenone ketyl radical formation occurs with entrapment in cellulose and also with inclusion in calix[6]arene and calix[8]arene while in silicalite only triplet–triplet absorption is detected.

The formation of inclusion complexes of β-phenylpropiophenone and benzophenone with p-tert-butylcalix[4], [6] and [8]arenes (powdered solid samples) was studied with the use of diffuse reflectance techniques. Experimental evidence was obtained for inclusion in all cases. The benzophenone n → π* absorption band exhibits hypsochromic shifts with an increase of the calixarene ring aperture, providing evidence for an increase in cavity polarity. β-Phenylpropiophenone exhibits strong room temperature phosphorescence in contrast to its solution behaviour, and this is a clear evidence for the inclusion of this probe within the calixarene molecules. Calix[4]arene and calix[8]arene provide a more rigid environment to β-phenylpropiophenone whereas calix[6]arene appears to be more flexible. Transient absorption spectra of inclusion complexes with benzophenone (1 : 1 mol : mol, excited at 355 nm) show major triplet formation in the calix[4]arene case, while the ketyl radical of benzophenone is formed in the calix[6]arene case and is predominant in the calix[8]arene case. Phenoxyl radical transient absorption also becomes evident in the last two cases. For β-phenylpropiophenone (1 : 1 mol : mol) phenoxyl radicals are formed but no evidence was found for triplet or ketyl radical formation of this ketone in the calix[4]arene case. However, strong support for the ketyl radical of the aryl alkyl ketone was found for calix[6]arene and calix[8]arene inclusion complexes.

The aim of the present study was to classify pathological gamblers based on their psychopathology as related to the variable sensation-seeking, and to check possible differences between the groups on the sociodemographic variables. The sample was composed of 110 male pathological gamblers using slot machines who requested treatment at the Pathological Gambling Unit at the Ciutat Sanitària i Universitària de Bellvitge. It was observed that pathological gamblers comprise three clusters, differentiated with differing severity depression, psychoticism, somatization, impulsiveness, interpersonal sensitivity, and phobic anxiety. Cluster 1, representing 46.7% of the sample, showed mean scores higher than or equal to T = 63. On the subscales of Depression, Psychoticism, Interpersonal Sensidvity, Phobic Anxiety, and Obsessiveness–Compulsiveness the score was close to T = 63 (the clinical cut-off score). Cluster 2, representing 23.8% of the sample, scored higher than Cluster 1 on the following subscales: Depression, Phobic Anxiety, Interpersonal Sensitivity, Psychoticism, Obsessive–Compulsive, and Somatization. On Cluster 3 highest mean scores were observed on all SCL-90-R dimensions relative to the other two groups. What distinguished these subgroups is not symptomatology but the severity of the psychopathology. On the other hand, sensation seeking was similar for the three clusters, and the slight differences depended on the subjects' psychopathology.

Sangemil spa area is located 16 km south of Viseu, Central Portugal, near the Dão river. The productive wells, F1 and F2 are located in the alluvial plain of the river and have been threatened by the river floods (Fig. 1). In order to locate new production wells, out of the alluvial plain and close to the spa unit the surrounding geological structure was surveyed. The proposed structural model claimed for a geophysical survey with two profiles P1 and P2 (Fig. 1) using dipole-dipole array. Taking into account the results obtained, three new wells, HDN1, HDN2 and HDN3 (Fig. 1) have been drilled (85 to 112m deep). The field measurements of conductivity, temperature, pH and yield are discussed in conjunction with the geophysical results.

O controle biológico vem reduzindo o uso de produtos químicos no combate a insetos pragas, com destaque para pentatomídeos predadores, os quais apresentam variações em seu ciclo de vida, principalmente em função do regime alimentar a que são submetidos. Assim, o objetivo deste trabalho foi estudar o desenvolvimento ninfal e a produtividade de Podisus distinctus (Stäl, 1860) (Heteroptera: Pentatomidae) alimentado com larvas de Bombyx mori L., 1758 (Lepidoptera: Bombycidae) (T1), comparado com larvas de Tenebrio molitor L., 1758 (Coleoptera: Tenebrionidae) (T2) ou Musca domestica L., 1758 (Diptera: Muscidae) (T3) à temperatura de 25 ± 0,5ºC, umidade relativa de 70 ± 2% e fotoperíodo de 12 h. P. distinctus, alimentado com B. mori, apresentou semelhante duração da fase ninfal (18,68 ± 1,02) em relação à alimentação com T. molitor (18,32 ± 1,49). Os períodos de pré-oviposição e oviposição e os números de ovos postos e de ninfas por fêmea foram maiores com B. mori (5,83 ± 2,02; 15,00 ± 7,40; 8,42 ± 1,84; 296,69 ± 154,75; e 228,55 ± 141,04, respectivamente), enquanto a longevidade de fêmeas e machos foi de 25,76 ± 16,15 e 35,00 ± 16,15 dias com T. molitor e de 20,57 ± 13,60 e 23,46 ± 12,35 dias com B. mori, respectivamente. Biological control has been reducing the use of chemical products against insect pests, specially predatory Pentatomidae. Species of this group can present high variations in their life cycle as a result of their diet. Thus, the objective of this research was to study nymph development and reproduction of Podisus distinctus (Stäl, 1860) (Heteroptera: Pentatomidae) fed on Bombyx mori L., 1758 (Lepidoptera: Bombycidae) larvae (T1), compared to those fed on Tenebrio molitor L., 1758 (Coleoptera: Tenebrionidae) (T2) and Musca domestica L., 1758 (Diptera: Muscidae) larvae (T3) at a temperature of 25 ± 0.5ºC, relative humidity of 70 ± 2%, and photophase of 12 h. Predators fed on B. mori showed duration of the nymph phase (18.68 ± 1.02) similar to those fed on T. molitor (18.32 ± 1.49). Pre-oviposition and oviposition periods and number of egg masses, besides eggs and nymphs per female, were higher with B. mori (5.83 ± 2.02; 15.00 ± 7.40; 8.42 ± 1.84; 296.69 ± 154.75; and 228.55 ± 141.04, respectively) while longevity of males and females of P. distinctus was 25.76 ± 16.15 and 35.00 ± 16.15 days with T. molitor, and 20.57 ± 13.60 and 23.46 ± 12.35 days with B. mori, respectively.