18 results on '"M. Laihosalo"'
Search Results
2. Is Persistent Visual Neglect Associated with Poor Survival?
- Author
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M. Jehkonen, M. Laihosalo, T. Saunamäki, A-M. Koivisto, P. Dastidar, and J-P. Ahonen
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2010
3. Anosognosia after stroke: assessment, occurrence, subtypes and impact on functional outcome reviewed
- Author
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Jani E Kettunen, Mervi Jehkonen, and M. Laihosalo
- Subjects
media_common.quotation_subject ,MEDLINE ,Neuropsychological Tests ,Outcome (game theory) ,Functional Laterality ,Neglect ,Developmental psychology ,Perceptual Disorders ,Disability Evaluation ,Predictive Value of Tests ,medicine ,Humans ,Generalizability theory ,Stroke ,media_common ,Cerebral Cortex ,Neurologic Examination ,Anosognosia ,General Medicine ,Prognosis ,medicine.disease ,Neurology ,Predictive value of tests ,Assessment methods ,Agnosia ,Neurology (clinical) ,Psychology ,Clinical psychology - Abstract
Purpose – This review provides an update on recent research findings concerning the methods used in the assessment of anosognosia, the occurrence and subtypes of anosognosia, the association between anosognosia and neglect, and the impact of anosognosias on functional outcome. Methods – A systematic review covering the period from 1995 to 2005 was carried out on reports drawn from electronic databases (MEDLINE, PSYCHLIT) and identified from the references in these reports. Twenty-seven articles met the selection criteria. Results – The results of this review are in line with previous findings in the following respects: anosognosia was more often associated with right hemisphere damage, neglect and anosognosia co-occurred, and anosognosia had predictive value on poor functional outcome. The variation in the methods used in the assessment of anosognosia, patient samples and assessment times influence the occurrence rates and the predictive value of anosognosia, which might undermine the generalizability of the results. Conclusions – More homogeneous patient samples and consistency in the assessment methods and evaluation times would facilitate comparisons of the occurrence and the impact of anosognosia on functional outcome. New methods need to be developed for the assessment of anosognosia. These new methods should take account of the subtypes of anosognosia both at verbal and at non-verbal levels.
- Published
- 2006
- Full Text
- View/download PDF
4. Fluctuation in spontaneous recovery of left visual neglect: a 1-year follow-up
- Author
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Mervi Jehkonen, Anna-Maija Koivisto, Jukka-Pekka Ahonen, Prasun Dastidar, and M. Laihosalo
- Subjects
Adult ,Male ,medicine.medical_specialty ,Activities of daily living ,Time Factors ,Spontaneous recovery ,Stroke severity ,1 year follow up ,Severity of Illness Index ,Functional Laterality ,Physical medicine and rehabilitation ,medicine ,Humans ,Aged ,Neurologic Examination ,Chi-Square Distribution ,Visual neglect ,Recovery of Function ,Middle Aged ,humanities ,Neurology ,Physical therapy ,Hemianopsia ,Female ,Neurology (clinical) ,Psychology ,human activities ,Follow-Up Studies - Abstract
Spontaneous recovery and possible fluctuation in left visual neglect, and its relation to stroke severity, basic activities of daily living (ADL) and extended ADL were examined at 10 days, at 3, 6, and 12 months after onset. Twenty-one of 56 right hemisphere stroke patients had visual neglect. Three visual neglect recovery groups were identified: continuous, fluctuating and poor recovery. We concentrated on the comparison of the continuous and the fluctuating recovery groups. At the acute phase the fluctuating recovery group had larger infarcts, more severe neglect and stroke, and a lower level of basic ADL compared to the continuous recovery group. In the continuous recovery group stable recovery was detected up to 6 months, whereas in the fluctuating recovery group recovery was incoherent in neglect and in extended ADL. A minimum follow-up period of 6 months including the evaluation of extended ADL is recommended for neglect patients due to possible fluctuation in visual neglect.
- Published
- 2007
5. Impact of neglect on functional outcome after stroke: a review of methodological issues and recent research findings
- Author
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M, Jehkonen, M, Laihosalo, and J E, Kettunen
- Subjects
Male ,Perceptual Disorders ,Stroke ,Treatment Outcome ,Terminology as Topic ,Stroke Rehabilitation ,Humans ,Female ,Middle Aged ,Aged ,Follow-Up Studies - Abstract
This study provides an update on recent research findings concerning neglect and its impact on functional outcome. The review covers studies published during the past ten years.A systematic review was carried out on reports drawn from electronic databases (MEDLINE and PSYCHLIT, January 1996 - August 2005) and identified from the lists of references in these reports. Unpublished reports, articles in other than the English language, and studies with non-human and non-adult subjects were excluded. The selection criteria were met by 26 articles.15 of the 26 studies recruited heterogeneous patient groups (patients with right and left and/or unspecified lesions). The results from homogeneous groups (right hemisphere patients) were more consistent, emphasizing neglect as an independent predictor of functional outcome. Studies with homogeneous patient groups used consecutive series of patients, standardized measures of neglect, and a broader concept of functional outcome (both motor and cognitive items) than those with heterogeneous patient groups. Follow-ups longer than one year were very rare.Neglect has a significant negative impact on functional outcome, either as an independent predictive factor or in connection with other variables. The results, however, are inevitably affected by differences in patient samples and in the methods used in assessing neglect and functional outcome. Research focusing on homogeneous patient groups and especially on left hemisphere patients is needed. Neglect should be assessed with a standardized test battery rather than a single test, and functional outcome should be measured with scales consisting of cognitive, social and motor items. Also longer follow-ups are needed to verify the long-term functional outcome of neglect patients.
- Published
- 2006
6. Neuropsychological functioning in right hemisphere infarct patients—Does thrombolytic treatment matter?
- Author
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Mervi Jehkonen, J. Ollikainen, Anna-Maija Koivisto, M. Laihosalo, Jani E Kettunen, and Prasun Dastidar
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medicine.medical_specialty ,Thrombolytic treatment ,Working memory ,Neuropsychology ,Cognition ,Audiology ,Executive functions ,Boston Naming Test ,Neurology ,Wisconsin Card Sorting Test ,medicine ,Verbal fluency test ,Neurology (clinical) ,Psychology - Abstract
the Screening Tests. (MMSE 291, ACE 926). Significant differences were found betweenpatients andnormal controls in the following tests: a) FrontalAssessment Battery (p=0.19); b) Conceptualization Subscale (p=0.006); c) Differ Memory Reys List (p=0.03), Boston Naming Test (p=0.019), Semantic Verbal Fluency (p=0.021); d) Letters and Numbers (p=0.033); e) Wisconsin Card Sorting Test (p=0.032); f) Hotel task deviation of time (p=0.018); g) Met-hv total failures (p=0.001), Aim Interpretation Subscale (p=0.003), Fulfillment of tasks Subscale (p=0.001), Inefficiencies Subscale (p=0.000) and h) Test of Attentional Performance, Flexibility Subscale (p=0.045). Conclusions: This study supports previous reports showing that there is a pattern of cognitive abnormalities after focal cerebellar damage that especially includes impairments of executive functions (planning, setshifting, abstract reasoning, verbal fluency, working memory). Moreover, it suggests that the ecological executive battery used in this investigation might be much more sensitive for the detection of deficits in real life executive functions in these patients.
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- 2009
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7. Contents Vol. 58, 2007
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M. Rosso, Simona Sacco, Pietro Lanzafame, J.-P. Ahonen, Paul-André Despland, L. Lopiano, Yin-Chen Huang, Karl-Olof Lövblad, Andrea O. Rossetti, A. Cinquepalmi, J.M.S. Pearce, A. Ducati, Gabriella Scullica, Alessia Bramanti, M. Jehkonen, Min Cheng, Giancarlo Iannizzotto, Francesco La Rosa, P. Dastidar, Yafeng Zhao, Carmine Marini, Marc Augsburger, Edoardo Sessa, E.K. Tan, Adam Szczuciński, Huailian Guo, Pierre-Yves Dietrich, Antonio Carota, Trygve Holmøy, Shun-Tai Yang, Nicolas de Tribolet, Yang-Lan Lo, Jacqueline Delavelle, François Lazeyras, Giuseppe Di Lorenzo, E. Torre, Tao-Chieh Yang, L.L. Chan, Denis Cerimagic, Xin Jin, Alessandro Alimenti, Clemens Bloetzer, B. Bergamasco, Luigi Olivieri, Francesca Pistoia, Li Huang, M. Lanotte, Alicja Kalinowska, Placido Bramanti, Jacek Losy, Arijana Lovrencic-Huzjan, F. Cankat Tulunay, M. Laihosalo, Hakan Ergün, M. Zibetti, Silvia Marino, A.-M. Koivisto, Vida Demarin, Hasan Yilmaz, Paolo Di Bella, Josip Glavic, Antonio Carolei, and Sinem Ezgi Gulmez
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Neurology ,Neurology (clinical) - Published
- 2007
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8. Starting point as an indicator of neglect in right hemisphere infarct patients
- Author
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Mervi Jehkonen, Prasun Dastidar, Jani E Kettunen, J. Ollikainen, Anna-Maija Koivisto, and M. Laihosalo
- Subjects
medicine.medical_specialty ,Neurology ,media_common.quotation_subject ,medicine ,Point (geometry) ,Neurology (clinical) ,Right hemisphere ,Audiology ,Psychology ,Neglect ,media_common - Published
- 2009
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9. Subject Index Vol. 58, 2007
- Author
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Marc Augsburger, Gabriella Scullica, Edoardo Sessa, Antonio Carota, J.-P. Ahonen, Jacqueline Delavelle, François Lazeyras, Adam Szczuciński, Huailian Guo, Shun-Tai Yang, Giuseppe Di Lorenzo, Paul-André Despland, Simona Sacco, Hasan Yilmaz, Placido Bramanti, M. Lanotte, M. Jehkonen, Andrea O. Rossetti, Yang-Lan Lo, Francesca Pistoia, Antonio Carolei, Sinem Ezgi Gulmez, Karl-Olof Lövblad, E.K. Tan, A. Cinquepalmi, Pietro Lanzafame, L.L. Chan, A.-M. Koivisto, Min Cheng, Yin-Chen Huang, P. Dastidar, Alessia Bramanti, Giancarlo Iannizzotto, Xin Jin, Yafeng Zhao, Pierre-Yves Dietrich, E. Torre, Paolo Di Bella, Francesco La Rosa, Hakan Ergün, Tao-Chieh Yang, M. Zibetti, Jacek Losy, Trygve Holmøy, Josip Glavic, Clemens Bloetzer, Arijana Lovrencic-Huzjan, A. Ducati, Silvia Marino, F. Cankat Tulunay, M. Laihosalo, Li Huang, Nicolas de Tribolet, Carmine Marini, Vida Demarin, B. Bergamasco, Luigi Olivieri, Alicja Kalinowska, Denis Cerimagic, L. Lopiano, M. Rosso, Alessandro Alimenti, and J.M.S. Pearce
- Subjects
Gerontology ,Index (economics) ,Neurology ,Subject (documents) ,Neurology (clinical) ,Psychology - Published
- 2007
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10. Rightward bias in right hemisphere infarct patients with or without thrombolytic treatment and in healthy controls.
- Author
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Kettunen JE, Laihosalo M, Ollikainen J, Dastidar P, Nurmi L, Koivisto AM, and Jehkonen M
- Subjects
- Adult, Aged, Brain Infarction complications, Brain Infarction drug therapy, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Orientation physiology, Perceptual Disorders etiology, Stroke complications, Stroke drug therapy, Treatment Outcome, Attention physiology, Brain physiopathology, Brain Infarction physiopathology, Functional Laterality physiology, Perceptual Disorders physiopathology, Stroke physiopathology, Thrombolytic Therapy
- Abstract
Right hemisphere (RH) infarct patients have a tendency to begin visual scanning from the right side of a given stimulus. Our aim was to find out whether RH patients with (T+) or without (T-) thrombolytic treatment and healthy controls differ in their starting points in three cancellation tasks. Our sample comprised of 77 patients and 62 controls. Thirty-four patients received thrombolysis. Rightward orientation bias was more evident in the T- group than in the T+ group. The T+ group showed a robust tendency to start all cancellation tasks more often on the right side than the controls. Regardless of whether they had visual neglect, patients in the T+ group showed still defective rightward orienting, possibly indicating residual attentional problems. The analyses of starting points in visual cancellation tasks provide additional information on residual symptoms of attention difficulties after stroke.
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- 2012
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11. Predictors of functional outcome after right hemisphere stroke in patients with or without thrombolytic treatment.
- Author
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Losoi H, Kettunen JE, Laihosalo M, Ruuskanen EI, Dastidar P, Koivisto AM, and Jehkonen M
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- Adult, Age Factors, Aged, Brain Ischemia complications, Brain Ischemia drug therapy, Disability Evaluation, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Perceptual Disorders etiology, Predictive Value of Tests, Severity of Illness Index, Stroke complications, Stroke drug therapy, Treatment Outcome, Activities of Daily Living, Brain Ischemia psychology, Perceptual Disorders psychology, Recovery of Function physiology, Stroke psychology, Thrombolytic Therapy
- Abstract
The purpose of this study was to assess the predictors of functional outcome after right hemisphere stroke at 6-month follow up in patients with or without thrombolytic treatment. Thrombolysis did not predict functional outcome in instrumental activities of daily living (IADL). Lower acute phase basic activities of daily living (ADL) measured by the Barthel Index was a statistically significant predictor of IADL when adjusted for age and education (p = .015) and had borderline significance (p = .076) as a predictor of functional outcome when adjusted for severity of stroke at admission. When stroke severity was taken into account also higher age became a statistically significant (p = .039) predictor of functional outcome. The acute phase neuropsychological symptoms predicted the functional outcome in unadjusted analyses but when adjusted for age, education, and severity of stroke no independent association was found.
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- 2012
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12. Driving ability in stroke patients with residual visual inattention: a case study.
- Author
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Jehkonen M, Saunamäki T, Alzamora AK, Laihosalo M, and Kuikka P
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- Adult, Aged, Humans, Male, Middle Aged, Neuropsychological Tests, Visual Fields, Attention, Automobile Driving psychology, Perceptual Disorders psychology, Stroke psychology, Visual Perception
- Abstract
Driving ability of three patients having a right hemisphere infarct and residual visual inattention was examined. The neuropsychological examination included the Peripheral Perception Test and the Signal Detection Test from the Vienna Test System, and the Behavioural Inattention Test (BIT). Driving ability was assessed with an on-road evaluation. The patients had no neglect based on the BIT and had normal visual fields, but they showed slightly poorer visual search on the left side. All patients passed the official on-road driving test and were considered capable of driving. This study raises the question if acute neglect can recover to a degree in which driving may be possible.
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- 2012
- Full Text
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13. Thrombolytic therapy and visuoperceptual functions in right hemisphere infarct patients.
- Author
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Laihosalo M, Kettunen JE, Koivisto AM, Dastidar P, Ollikainen J, and Jehkonen M
- Subjects
- Aged, Brain Infarction etiology, Case-Control Studies, Female, Humans, Male, Middle Aged, Neurologic Examination, Neuropsychological Tests, Photic Stimulation methods, Retrospective Studies, Severity of Illness Index, Stroke complications, Stroke drug therapy, Visual Perception physiology, Brain Infarction drug therapy, Brain Infarction physiopathology, Functional Laterality, Thrombolytic Therapy methods, Visual Perception drug effects
- Abstract
This study examines the association between thrombolysis and visuoperceptual functions in right hemisphere (RH) infarct patients. Fifty-six consecutive patients with first acute RH infarct were matched for age, years of education and stroke severity at the time of admission to the emergency department (baseline NIHSS; National Institute of Health Stroke Scale), compared according to whether (T+) or not (T-) they received thrombolysis. Neurological (NIHSS at hospital ward; Barthel index; BI) and neuropsychological examinations were conducted 4 days after onset. Visuoconstructive abilities were assessed with the block design and visual search and reasoning with the picture completion subtests of the Wechsler Adult Intelligence Scale revised. Visual neglect was assessed with the conventional subtests of the Behavioural Inattention test and visual memory with the visual reproduction subtest of the Wechsler Memory Scale Revised. T+ and T- patients did not differ in baseline NIHSS, age, years of education, hemianopia, hemiparesis, or in basic ADL (BI). T- patients had more severe strokes (NIHSS at hospital ward) and poorer visuoconstructive abilities than T+ patients. Our results indicate that thrombolysis has a favourable effect on visuoperceptual functions in acute stroke.
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- 2011
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14. Is persistent visual neglect associated with poor survival?
- Author
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Jehkonen M, Laihosalo M, Saunamäki T, Koivisto AM, Dastidar P, and Ahonen JP
- Abstract
Background: The association of visual neglect with survival after right hemisphere (RH) stroke has received only limited attention., Objective: This study explores the relationship of visual neglect and its spontaneous recovery to survival in a homogenous patient group with first-ever RH stroke., Methods: Fifty-one RH stroke patients who suffered an infarct between 1994 and 1997 were retrospectively followed for survival until August 31, 2009. Acute-phase neurological, neuropsychological and neuroradiological data were studied to identify predictors of survival., Results: Twenty-eight patients died during the follow-up. Age, education, and poor recovery of visual neglect emerged as significant single predictors of death. The best set of predictors for poor survival in the multivariate model was poor recovery of visual neglect and low education., Conclusions: Poor recovery of visual neglect is associated with long-term mortality in RH infarct patients. The follow-up of RH patients' neuropsychological performance gives additional information about the prognosis.
- Published
- 2010
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15. Right hemisphere infarct patients and healthy controls: evaluation of starting points in cancellation tasks.
- Author
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Nurmi L, Kettunen J, Laihosalo M, Ruuskanen EI, Koivisto AM, and Jehkonen M
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- Adult, Aged, Female, Humans, Male, Middle Aged, Neuropsychological Tests, ROC Curve, Retrospective Studies, Statistics, Nonparametric, Stroke complications, Brain Infarction pathology, Brain Infarction physiopathology, Functional Laterality physiology, Perceptual Disorders complications, Perceptual Disorders etiology, Visual Perception
- Abstract
Patients with visual neglect (VN) tend to start cancellation tasks from the right. This exceptional initial rightward bias is also seen in some right hemisphere (RH) stroke patients who do not meet the criteria of VN in conventional tests. The present study compared RH infarct patients' (examined on average 4 days post-stroke) and healthy controls' starting points (SPs) in three cancellation tasks of the Behavioural Inattention Test (BIT). Furthermore, task-specific guideline values were defined for a normal SP to differentiate the performance of healthy subjects from that of patients with subclinical inattention. Conventional tests indicated that 15 of the 70 RH infarct patients had VN. The control group comprised 44 healthy volunteers. In each task, the VN group started the cancellations mainly from the right. The non-neglect and healthy groups initiated most cancellations from the left, more so in the healthy group. Starting more than one BIT task outside the guideline value indicated pathological inattention, as this was typical among the VN patients, but exceptional among the healthy subjects. One-third of the non-neglect patients showed pathological inattention by starting more than one task outside the guideline value. Clinical assessment of VN should, therefore, include an evaluation of the SPs to detect this subtle form of neglect.
- Published
- 2010
- Full Text
- View/download PDF
16. [Not Available].
- Author
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Jehkonen M, Kettunen JE, Laihosalo M, and Saunamäki T
- Published
- 2007
17. Fluctuation in spontaneous recovery of left visual neglect: a 1-year follow-up.
- Author
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Jehkonen M, Laihosalo M, Koivisto AM, Dastidar P, and Ahonen JP
- Subjects
- Adult, Aged, Chi-Square Distribution, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neurologic Examination methods, Severity of Illness Index, Time Factors, Functional Laterality, Hemianopsia physiopathology, Recovery of Function physiology
- Abstract
Spontaneous recovery and possible fluctuation in left visual neglect, and its relation to stroke severity, basic activities of daily living (ADL) and extended ADL were examined at 10 days, at 3, 6, and 12 months after onset. Twenty-one of 56 right hemisphere stroke patients had visual neglect. Three visual neglect recovery groups were identified: continuous, fluctuating and poor recovery. We concentrated on the comparison of the continuous and the fluctuating recovery groups. At the acute phase the fluctuating recovery group had larger infarcts, more severe neglect and stroke, and a lower level of basic ADL compared to the continuous recovery group. In the continuous recovery group stable recovery was detected up to 6 months, whereas in the fluctuating recovery group recovery was incoherent in neglect and in extended ADL. A minimum follow-up period of 6 months including the evaluation of extended ADL is recommended for neglect patients due to possible fluctuation in visual neglect., ((c) 2007 S. Karger AG, Basel.)
- Published
- 2007
- Full Text
- View/download PDF
18. Impact of neglect on functional outcome after stroke: a review of methodological issues and recent research findings.
- Author
-
Jehkonen M, Laihosalo M, and Kettunen JE
- Subjects
- Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Perceptual Disorders diagnosis, Perceptual Disorders etiology, Stroke complications, Stroke diagnosis, Terminology as Topic, Treatment Outcome, Perceptual Disorders physiopathology, Perceptual Disorders rehabilitation, Stroke Rehabilitation
- Abstract
Purpose: This study provides an update on recent research findings concerning neglect and its impact on functional outcome. The review covers studies published during the past ten years., Methods: A systematic review was carried out on reports drawn from electronic databases (MEDLINE and PSYCHLIT, January 1996 - August 2005) and identified from the lists of references in these reports. Unpublished reports, articles in other than the English language, and studies with non-human and non-adult subjects were excluded. The selection criteria were met by 26 articles., Results: 15 of the 26 studies recruited heterogeneous patient groups (patients with right and left and/or unspecified lesions). The results from homogeneous groups (right hemisphere patients) were more consistent, emphasizing neglect as an independent predictor of functional outcome. Studies with homogeneous patient groups used consecutive series of patients, standardized measures of neglect, and a broader concept of functional outcome (both motor and cognitive items) than those with heterogeneous patient groups. Follow-ups longer than one year were very rare., Conclusions: Neglect has a significant negative impact on functional outcome, either as an independent predictive factor or in connection with other variables. The results, however, are inevitably affected by differences in patient samples and in the methods used in assessing neglect and functional outcome. Research focusing on homogeneous patient groups and especially on left hemisphere patients is needed. Neglect should be assessed with a standardized test battery rather than a single test, and functional outcome should be measured with scales consisting of cognitive, social and motor items. Also longer follow-ups are needed to verify the long-term functional outcome of neglect patients.
- Published
- 2006
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