1. Fatal Toxic Leukoencephalopathy Secondary to Overdose of a New Psychoactive Designer Drug 2C-E ('Europa')
- Author
-
Justin Sacks, M. Jordan Ray, Sue Williams, and Michael J. Opatowsky
- Subjects
Hallucinogen ,medicine.medical_specialty ,Recreational Drug ,medicine.drug_class ,business.industry ,Cerebral white matter ,General Medicine ,030204 cardiovascular system & hematology ,Pharmacology ,medicine.disease ,Designer drug ,Toxic leukoencephalopathy ,03 medical and health sciences ,Case Studies ,0302 clinical medicine ,Toxic injury ,030225 pediatrics ,medicine ,business ,Intensive care medicine - Abstract
We present a case of a fatal toxic leukoencephalopathy following ingestion of a new psychoactive designer drug known as 2C-E or "Europa." Recreational drugs, particularly hallucinogenic substances, appear to be growing in popularity, with increasing amounts of information available via the Internet to entice potential users. In addition, some newer "designer" psychoactive substances are available for purchase online without adverse legal consequences, therefore adding to their popularity. We describe magnetic resonance imaging (MRI) findings to include selective diffuse toxic injury of the cerebral white matter with sparing of the cortex and most of the deep gray nuclei. To our knowledge, this is the first reported description of cerebral findings on MRI that are likely related to a lethal ingestion of 2C-E.
- Published
- 2012
- Full Text
- View/download PDF