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Background Real-world treatment of ulcerative colitis (UC) requires a patient-centric, holistic definition of ‘comprehensive remission' that goes beyond standard regulatory definitions. In an international initiative, we reviewed aspects of UC that affect patients and attempted to achieve consensus on which aspects should be considered in a definition of ‘comprehensive remission’, using a modified Delphi process. This initiative summarized expert consensus recommendations on aspects of UC that are important to patients and that affect their lives, how to measure and score these aspects, and objective markers of mucosal inflammation that are relevant to evaluate in remission, such as endoscopic and histological activity and inflammatory biomarkers. Methods The Delphi consensus panel comprised 10 physicians with expertise in UC and one patient advocate, and two additional physicians chaired the process. To inform the Delphi statements, we asked 18 patients about their experiences of living with UC in remission, asked panel members about their experience of treating patients and systematically reviewed associations between outcome measures in UC. Panel members voted on a 6-point Likert scale in three rounds of anonymous voting, the final round of which was preceded by a live discussion. Consensus was met if ≥ 67% of the panel agreed with the statement (4–6 on the 6-point Likert scale). Statements not meeting consensus in voting rounds 1 and 2 were revised and any not meeting consensus by the end of voting round 3 were discarded (Figure 1). Results The panel agreed that a definition of comprehensive remission should include aspects of UC that are currently measured in clinical trials (blood in stools, stool frequency, disease-related quality of life [QoL], endoscopic remission, histological inflammatory activity, inflammatory biomarkers and discontinuation of corticosteroids), but also additional patient-reported symptoms should be added. These were bowel urgency, abdominal pain, extra-intestinal manifestations, fatigue and sleep disturbance (Table 1). Suggestions for how the severity could be measured and thresholds for remission were agreed for each aspect, with the exception of extra-intestinal manifestations. Disease activity evaluated using ultrasound was voted as important to consider but was not recommended to be included in a measure of comprehensive remission at this stage. Conclusion We used a robust methodology to reach agreement and provide recommendations on the aspects of UC that can be used to define comprehensive remission and assessed in clinical practice. We plan to develop this as a combined measure which may also have applicability in clinical trials.

CO2GeoNet, Autumn webinar - online

Calcium Looping (CaL) is recognized as one of the most promising emerging technology for CO2 capture in cement plants. The highly integrated Calcium Looping process configuration enables CO2 capture with an efficiency target over 90% and high-energy efficiency. The core activity of the CLEANKER project is the design, construction and operation of a CaL demonstration system including the entrained-flow carbonator (the CO2 absorber) and the entrained-flow oxyfuel calciner (the sorbent regenerator). This demonstration system, connected to the Buzzi Unicem kiln of the Vernasca cement plant (Italy), will capture the CO2 from a portion of the flue gases of the kiln, using as CO2 sorbent the same raw meal that is used for clinker production. The CLEANKER implementation plan spans four years and half, from October 2017 to March 2022 (an extension of six months has been requested due to the pandemic situation). The first two years have been devoted to the (i) detailed design of the CaL demonstration system, the (ii) characterization of raw meals as CO2 sorbents and the (iii) erection of the demonstrator. The pilot plant has been commissioned in October 2020 and then will be demonstrated by means of several short and long steady-state tests (during spring and summer 2021), with the aim of optimizing the operational parameters governing the CO2 capture process and of bringing the integrated CaL technology at TRL7. The pilot plant and the conventional kiln operations will be deeply integrated: the CaL calciner will be fed by the same kind of raw meal used in the kiln for producing clinker, whereas the carbonator will treat the effluents coming from the cement plant. The CaL calciner will be fired in a recirculated oxy-fuel combustion mode, where a heavy fuel oil will be burnt with oxygen and a fraction of the CO2-rich exhausts will be recirculated to control the oxidant composition. Before being recycled to the CaL calciner inlet, this CO2-rich stream will be properly cooled in a regenerative riser-cyclone stage, designed to preheat the fresh raw meal-based sorbent fed to the pilot, minimizing the additional fuel supplied to run the calcium looping process. In the carbonator, the amount of sorbent (FCa/FCO2) will be tuned either by increasing the raw meal exchanged with the CaL calciner or by internally recycling a fraction of sorbent from the carbonator outlet to the inlet. First short campaigns will be carried out by specialized Buzzi Unicem operators (assisted by CLEANKER partners such as, Politecnico di Milano, Laboratorio Energia e Ambiente Piacenza, IKN, University of Stuttgart and VDZ) to test the process performances as a function of the type of raw meal, the amount of sorbent (solid to gas ratio in the carbonator) and the carbonation/calcination operating temperatures. The experimental activity will prove the stability and the effectiveness of the process by running over hundreds of hours the optimal experimental configuration, capable of achieving a constant carbon capture rate higher than 90%. Besides the continuous monitoring of process temperatures, flow rates and gas compositions, the experimental campaigns will be supported by post-processing sorbent analysis, in order to evaluate the capture capacity of the raw meal and the extent of side reactions. Test results will be exploited to validate simulation models and to improve the future scale-up and the design of an industrial size CaL plant

CLEANKER proceedings at 15th Greenhouse Gas Control Technologies Conference 15-18 March 2021 (GHGT-15)

Although the phenomenon has been known, and investigated, as early as the nineteenth century, the interest in understanding Alpine lee cyclogenesis (often called Genoa cyclogenesis) has grown since the middle twentieth century, when it was realized that the largest fraction of cyclones affecting the central-eastern Mediterranean and later Eastern Europe originated in the area south of the Alps, more often in the Gulf of Genoa. Forecasting this type of cyclogenesis remained a challenging task until at least the mid- late 1980s, even after the development of the earlier NWP models, which failed in predicting this phenomenon, lacking the ability to adequately represent the orographic forcing. Monitoring and understanding of cyclogenesis in the lee of the Alps was the main objective of field projects, the most important being GARP-ALPEX in 1982. The following years were full of ideas and theories about this phenomenon, which is representative of orographic cyclogenesis in other regions of the world. The main steps in understanding the complex phenomenon of lee cyclogenesis, with particular reference to the Alps, are outlined here, focusing on theoretical explanations.

Background Fetal smoke exposure is a common and key avoidable risk factor for birth complications and seems to influence later risk of overweight. It is unclear whether this increased risk is also present if mothers smoke during the first trimester only or reduce the number of cigarettes during pregnancy, or when only fathers smoke. We aimed to assess the associations of parental smoking during pregnancy, specifically of quitting or reducing smoking and maternal and paternal smoking combined, with preterm birth, small size for gestational age, and childhood overweight. Methods and findings We performed an individual participant data meta-analysis among 229,158 families from 28 pregnancy/birth cohorts from Europe and North America. All 28 cohorts had information on maternal smoking, and 16 also had information on paternal smoking. In total, 22 cohorts were population-based, with birth years ranging from 1991 to 2015. The mothers’ median age was 30.0 years, and most mothers were medium or highly educated. We used multilevel binary logistic regression models adjusted for maternal and paternal sociodemographic and lifestyle-related characteristics. Compared with nonsmoking mothers, maternal first trimester smoking only was not associated with adverse birth outcomes but was associated with a higher risk of childhood overweight (odds ratio [OR] 1.17 [95% CI 1.02–1.35], P value = 0.030). Children from mothers who continued smoking during pregnancy had higher risks of preterm birth (OR 1.08 [95% CI 1.02–1.15], P value = 0.012), small size for gestational age (OR 2.15 [95% CI 2.07–2.23], P value < 0.001), and childhood overweight (OR 1.42 [95% CI 1.35–1.48], P value < 0.001). Mothers who reduced the number of cigarettes between the first and third trimester, without quitting, still had a higher risk of small size for gestational age. However, the corresponding risk estimates were smaller than for women who continued the same amount of cigarettes throughout pregnancy (OR 1.89 [95% CI 1.52–2.34] instead of OR 2.20 [95% CI 2.02–2.42] when reducing from 5–9 to ≤4 cigarettes/day; OR 2.79 [95% CI 2.39–3.25] and OR 1.93 [95% CI 1.46–2.57] instead of OR 2.95 [95% CI 2.75–3.15] when reducing from ≥10 to 5–9 and ≤4 cigarettes/day, respectively [P values < 0.001]). Reducing the number of cigarettes during pregnancy did not affect the risks of preterm birth and childhood overweight. Among nonsmoking mothers, paternal smoking was associated with childhood overweight (OR 1.21 [95% CI 1.16–1.27], P value < 0.001) but not with adverse birth outcomes. Limitations of this study include the self-report of parental smoking information and the possibility of residual confounding. As this study only included participants from Europe and North America, results need to be carefully interpreted regarding other populations. Conclusions We observed that as compared to nonsmoking during pregnancy, quitting smoking in the first trimester is associated with the same risk of preterm birth and small size for gestational age, but with a higher risk of childhood overweight. Reducing the number of cigarettes, without quitting, has limited beneficial effects. Paternal smoking seems to be associated, independently of maternal smoking, with the risk of childhood overweight. Population strategies should focus on parental smoking prevention before or at the start, rather than during, pregnancy. © 2020 Philips et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Community-acquired pneumonia (CAP) is one of the major causes of morbidity, mortality and hospitalization, and S. pneumoniae is the most frequently isolated etiologic agent. The pneumococcal urinary antigen test (PUAT) is among the recommended methods to identify the causative agent in CAP patients. A novel PUAT (IMMUNOCATCH

The 14th CO2GeoNet Open Forum 2019has been held at San Servolo Island, Venice, Italy on 6-9 May 2019. Go to te conference website by clicking here to see the program, the Keynote Speech, CVs and photos of all the speakers, and to download the presentations.

The CLEANKER project got EC support from October 2017 to September 2021 under the Horizon 2020 call LCE 29 – 2017 . CLEANKER (www.cleanker.eu) aims at demonstrating at TRL7 the Calcium Looping (CaL) concept in a configuration highly integrated with the cement production process, making use of entrained flow reactors. The cement industry is a key-sector for the reduction of CO2 emissions. CO2 generation in cement production processes in fact, cannot be disregarded due to the calcination of limestone (CaCO3 dissociated to CaO and CO2), the most important raw material. Around 60% of the direct CO2 emissions from the clinker burning process are due to this reaction. In addition, there are the emissions from combustion of mostly fossil fuels, as well as the generation of electric power required by the process (e.g. grinding), as indirect CO2 emissions. Cement production is thus responsible for about 27% of global anthropogenic CO2 emissions from industrial sources worldwide and for 5% of anthropogenic global CO2 emissions . According to IEA and ZEP studies, cement industry should contribute to the largest CO2 emission reduction through CCS in Europe, in order to meet the target of 2°C of global temperature increase (IEA 2DS scenario).

Objective: To assess the separate and combined associations of maternal pre-pregnancy body mass index (BMI) and gestational weight gain with the risks of pregnancy complications and their population impact. Design: Individual participant data meta-analysis of 39 cohorts. Setting: Europe, North America, and Oceania. Population: 265 270 births. Methods: Information on maternal pre-pregnancy BMI, gestational weight gain, and pregnancy complications was obtained. Multilevel binary logistic regression models were used. Main outcome measures: Gestational hypertension, pre-eclampsia, gestational diabetes, preterm birth, small and large for gestational age at birth. Results: Higher maternal pre-pregnancy BMI and gestational weight gain were, across their full ranges, associated with higher risks of gestational hypertensive disorders, gestational diabetes, and large for gestational age at birth. Preterm birth risk was higher at lower and higher BMI and weight gain. Compared with normal weight mothers with medium gestational weight gain, obese mothers with high gestational weight gain had the highest risk of any pregnancy complication (odds ratio 2.51, 95% CI 2.31– 2.74). We estimated that 23.9% of any pregnancy complication was attributable to maternal overweight/obesity and 31.6% of large for gestational age infants was attributable to excessive gestational weight gain. Conclusions: Maternal pre-pregnancy BMI and gestational weight gain are, across their full ranges, associated with risks of pregnancy complications. Obese mothers with high gestational weight gain are at the highest risk of pregnancy complications. Promoting a healthy pre-pregnancy BMI and gestational weight gain may reduce the burden of pregnancy complications and ultimately the risk of maternal and neonatal morbidity. Tweetable abstract: Promoting a healthy body mass index and gestational weight gain might reduce the population burden of pregnancy complications. © 2019 Royal College of Obstetricians and Gynaecologists

Importance: Both low and high gestational weight gain have been associated with adverse maternal and infant outcomes, but optimal gestational weight gain remains uncertain and not well defined for all prepregnancy weight ranges. Objectives: To examine the association of ranges of gestational weight gain with risk of adverse maternal and infant outcomes and estimate optimal gestational weight gain ranges across prepregnancy body mass index categories. Design, Setting, and Participants: Individual participant-level meta-analysis using data from 196 670 participants within 25 cohort studies from Europe and North America (main study sample). Optimal gestational weight gain ranges were estimated for each prepregnancy body mass index (BMI) category by selecting the range of gestational weight gain that was associated with lower risk for any adverse outcome. Individual participant-level data from 3505 participants within 4 separate hospital-based cohorts were used as a validation sample. Data were collected between 1989 and 2015. The final date of follow-up was December 2015. Exposures: Gestational weight gain. Main Outcomes and Measures: The main outcome termed any adverse outcome was defined as the presence of 1 or more of the following outcomes: preeclampsia, gestational hypertension, gestational diabetes, cesarean delivery, preterm birth, and small or large size for gestational age at birth. Results: Of the 196 670 women (median age, 30.0 years [quartile 1 and 3, 27.0 and 33.0 years] and 40 937 were white) included in the main sample, 7809 (4.0%) were categorized at baseline as underweight (BMI

presentations and posters

Presentation given at R2B Expo (Bologna, Italy) - 2018

Poster presented at CO2GeoNet Open Forum - San Servolo, Venice and Innovation in Industrial carbon Capture Conference (LEILAC project) - Liege, Belgium &nbsp

Il cemento è un materiale antico: è stato inventato dai romani ma brevettato dai francesi e dagli inglesi solo 200 anni fa. È applicato in molte opere pubbliche (ponti, strade, edifici, …) con funzioni strutturali; recentemente è stato anche utilizzato per produzioni artistiche (basti pensare al padiglione Italia di Expo 2015 a Milano). Il cemento è quindi un materiale che, pur antico, grazie alla sua versatilità riesce sempre a risultare moderno. Spesso però se ne parla senza capire esattamente di cosa si tratti.

Background: Gestational weight gain differs according to pre-pregnancy body mass index and is related to the risks of adverse maternal and child health outcomes. Gestational weight gain charts for women in different pre-pregnancy body mass index groups enable identification of women and offspring at risk for adverse health outcomes. We aimed to construct gestational weight gain reference charts for underweight, normal weight, overweight, and grades 1, 2 and 3 obese women and to compare these charts with those obtained in women with uncomplicated term pregnancies. Methods: We used individual participant data from 218,216 pregnant women participating in 33 cohorts from Europe, North America, and Oceania. Of these women, 9065 (4.2%), 148,697 (68.1%), 42,678 (19.6%), 13,084 (6.0%), 3597 (1.6%), and 1095 (0.5%) were underweight, normal weight, overweight, and grades 1, 2, and 3 obese women, respectively. A total of 138, 517 women from 26 cohorts had pregnancies with no hypertensive or diabetic disorders and with term deliveries of appropriate for gestational age at birth infants. Gestational weight gain charts for underweight, normal weight, overweight, and grade 1, 2, and 3 obese women were derived by the Box-Cox t method using the generalized additive model for location, scale, and shape. Results: We observed that gestational weight gain strongly differed per maternal pre-pregnancy body mass index group. The median (interquartile range) gestational weight gain at 40 weeks was 14.2 kg (11.4-17.4) for underweight women, 14.5 kg (11.5-17.7) for normal weight women, 13.9 kg (10.1-17.9) for overweight women, and 11.2 kg (7.0-15.7), 8.7 kg (4.3-13.4) and 6.3 kg (1.9-11.1) for grades 1, 2, and 3 obese women, respectively. The rate of weight gain was lower in the first half than in the second half of pregnancy. No differences in the patterns of weight gain were observed between cohorts or countries. Similar weight gain patterns were observed in mothers without pregnancy complications. Conclusions: Gestational weight gain patterns are strongly related to pre-pregnancy body mass index. The derived charts can be used to assess gestational weight gain in etiological research and as a monitoring tool for weight gain during pregnancy in clinical practice. © 2018 The Author(s).

Biomass refers to any organic materials that are derived from plants (including algae, trees and crops) and comprises material which has an organic origin. This leads to a wide range of possible sources of biomass each with their own composition and to different possible classifications. In the energy field, “biomass” refers to the organic matter (living or residue) that can be used as combustible material or energy source for power generation, heat or biofuels. After a description of the main types of biomass used in the energy field, their composition is given and the main parameters to evaluate their energy potential are listed and commented. In particular, the energy potential of virgin biomass, both terrestrial and aquatic, and waste biomass is investigated. An analysis on the availability of the biomass is outlined together with its worldwide productivity. Finally, a list of limitation of energy production from this resource related to historical, technical, economic, environmental and social reasons is described.

When applied to a system of sizeable vertical extent that can undergo adiabatic expansion/compression, the Rayleigh-Benard treatment of convection between two parallel plates, kept at constant temperature, needs to be amended with the consideration of potential temperature as the conserved thermodynamic variable. The fixed-temperature boundary conditions are therefore expressed as a combination of potential temperature and pressure, and this causes the solutions to be a mixture of the odd and even modes of the classical problem. Here, solutions are presented for a rotating system, which supports both stationary and oscillatory modes. While the stationary modes are all stabilized by this mechanism, as was shown previously for a nonrotating system, the oscillatory modes can have a lower critical Rayleigh number than their traditional counterpart, when the Prandtl number is approximately between 0.2 and 1.0.When applied to a system of sizeable vertical extent that can undergo adiabatic expansion/compression, the Rayleigh-Benard treatment of convection between two parallel plates, kept at constant temperature, needs to be amended with the consideration of potential temperature as the conserved thermodynamic variable. The fixed-temperature boundary conditions are therefore expressed as a combination of potential temperature and pressure, and this causes the solutions to be a mixture of the odd and even modes of the classical problem. Here, solutions are presented for a rotating system, which supports both stationary and oscillatory modes. While the stationary modes are all stabilized by this mechanism, as was shown previously for a nonrotating system, the oscillatory modes can have a lower critical Rayleigh number than their traditional counterpart, when the Prandtl number is approximately between 0.2 and 1.0.

Gasification of pelletized sugar cane bagasse, the waste residue from sugar cane, was carried out using an atmospheric pressure 100 kWth steam-oxygen blown circulating fluidized bed gasifier (CFBG). The purification of the syngas produced was carried out using a high temperature filter unit which contains 3 rigid ceramic candles with an outer diameter of 60 mm and a length of 1500 mm. Keeping the gasification temperature in the range of 800°-860°C and using magnesite M85 as the bed material, the effects of operational conditions (e.g. steam to biomass ratio (SBR) and oxygen to biomass stoichiometric ratio (ER)) and of catalytic and non-catalytic filtration on the composition distribution of the product gas and tar formation were investigated. Higher temperature and SBR values were favorable for increasing the mole ratio H2 to CO and decreasing the tar compound (PAH) concentration on dry basis, measured via solid phase adsorption (SPA) sampling and subsequent GC analysis varying from approximately 2 to 6 g/mn 3. At the same operational conditions, in the downstream filter, the conversion of tar content obtained using catalytic filter candles increased by a factor of 2.8 compared to the one with non-catalytic filter elements. The specification and distribution of major ash forming elements were investigated by SEM-EDS. Experimental results showed that bagasse is an interesting fuel for syngas production via the gasification process, both from a gas composition and from a tar production point of view.

RSE's Distributed Energy Resources Test Facility has been included as active user in A2A Lambrate Smart Grid Project. The Test Facility control system makes possible to manage the various generation systems available, behaving as a unique controllable unit by the DSO. This activity allowed to test functions such as active and reactive power control, remote disconnection and fault detection, as well as to verify the interoperability thanks to the adoption of standards such as IEC61850.

The cellular basis of cardiac pacemaking is still debated. Reliable computationalmodels of the sinoatrial node (SAN) action potential (AP) may help gain a deeper understanding of the phenomenon. Recently, novel models incorporating detailed Ca2+-handling dynamics have been proposed, but they fail to reproduce a number of experimental data, and more specifically effects of ‘funny’ (If ) current modifications. We therefore developed a SAN AP model, based on available experimental data, in an attempt to reproduce physiological and pharmacological heart rate modulation. Cell compartmentalization and intracellular Ca2+-handling mechanisms were formulated as in the Maltsev–Lakatta model, focusing on Ca2+-cycling processes. Membrane current equations were revised on the basis of published experimental data.Modifications of the formulation of currents/pumps/exchangers to simulate If blockers, autonomic modulators and Ca2+-dependent mechanisms (ivabradine, caesium, acetylcholine, isoprenaline, BAPTA) were derived from experimental data. The model generates AP waveforms typical of rabbit SAN cells, whose parameters fall within the experimental ranges: 352 ms cycle length, 80 mV AP amplitude, −58 mV maximum diastolic potential (MDP), 108 ms APD50, and 7.1Vs−1 maximum upstroke velocity. Rate modulation by If -blocking drugs agrees with experimental findings: 20% and 22% caesium-induced (5mM) and ivabradine-induced (3 μM) rate reductions, respectively, due to changes in diastolic depolarization (DD) slope, with no changes in either MDP or take-off potential (TOP). The model consistently reproduces the effects of autonomic modulation: 20% rate decreasewith 10 nMacetylcholine and28%increasewith 1 μMisoprenaline, again entirely due C 2012 The Authors. The Journal of Physiology C 2012 The Physiological Society DOI: 10.1113/jphysiol.2012.229435 4484 S. Severi and others J Physiol 590.18 to increase in theDDslope,with no changes in eitherMDPorTOP.Model testing of BAPTAeffects showed slowing of rate, −26%, without cessation of beating. Our up-to-date model describes satisfactorily experimental data concerning autonomic stimulation, funny-channel blockade and inhibition of the Ca2+-related system by BAPTA, making it a useful tool for further investigation. Simulation results suggest that a detailed description of the intracellular Ca2+ fluxes is fully compatiblewith the observation that If is a major component of pacemaking and rate modulation.

Few tests have been carried out in order to evaluate the use of cardoon in gasification and combustion applications most of the researchers dealt with agglomeration problems. The aim of this work is to deal with the agglomeration problem and to present a solution for the utilization of this biofuel at a near industrial application scale. For this reason, two experiments were conducted, one in TU Delft and one in Centre for Research and Technology Hellas (CERTH), using fuel cardoon and 50% w/w cardoon blended with 50% w/w giant reed respectively. Both experimental campaigns were carried out in similar atmospheric circulating fluidized bed gasifiers. Apart from the feedstock, the other differences were the gasification medium and the bed material used in each trial. The oxidizing agent at TUD׳s run was O2/steam, whereas CERTH׳s tests used air. When experiments with the cardoon 50% w/w–giant reed 50% w/w blend were performed no agglomeration problems were presented. Consequently, gasification could be achieved in higher temperature than that of pure cardoon which led to the reduction of tar concentration.

Updated stellar rates for the reaction {sup 23}Mg(p,{gamma}){sup 24}Al are calculated by using all available experimental information on {sup 24}Al excitation energies. Proton and {gamma}-ray partial widths for astrophysically important resonances are derived from shell-model calculations. Correspondences of experimentally observed {sup 24}Al levels with shell-model states are based on application of the isobaric multiplet mass equation. Our new rates suggest that the {sup 23}Mg(p,{gamma}){sup 24}Al reaction influences the nucleosynthesis in the mass A{gt}20 region during thermonuclear runaways on massive white dwarfs. {copyright} {ital 1998} {ital The American Physical Society}

Intestinal aspergillosis is an infection with a very high death rate especially in leukemic patients. Here we describe a case of a 46 years old woman with acute myeloid leukemia (LAM M5) who developed intestinal primary aspergillosis. This patient was diagnosed with LAM M5 through bone marrow aspiration and bone biopsy in March 2004. Symptoms of the disease were slight persistent fever, weight loss, asthenia, anemia, thrombocytopenia,and leukocytosis with high number of blasts in peripheral blood. After induction chemotherapy with ICE (Ifosfamide, Carboplatin, Etoposide), she developed neutropenia and high fever without apparent infective foci. She was treated with empiric antibiotic therapy, nevertheless she developed an intense diarrhea and ileo-cecal distention. Diagnostic exams didn't show signs of a focal lesion. Despite the change in antibiotic treatment and the transfusions of granulocytes and blood cells, the patient developed extremely critical conditions with persistence of neutropenia and abdominal distention. A surgical treatment was decided at the time. We treated the patient with a two steps surgical procedure. The first step was a right abdominal ileostomy followed by improvement of general conditions and then the second step a right colectomy. The histological morphology confirmed necrotizing colitis with Aspergillus ife. At that time , treatment with voriconazole was started. The general conditions of the patient improved rapidly and we were able to treat the patient with other medical anti-leukemic therapies. The patient is now cured and in healthy state. We obtained a good clinical result as only in other few cases described in literature.

presentazione di un modello operazionale di storm surge per il Mediterraneo

Enlargement of paranasal sinuses with air is rare with less than 50 cases reported in the medical literature. This craniofacial malformation was first described by Meyes in 1898 and its aetiology still remains unknown. Local pain, ocular alterations, anosmia, headache and cosmetic disturbances are the most common symptoms. We present a case of pneumosinus dilatans diagnosed in a male, 8 years of age. He presented with left fronto-orbital bossing that enlarged slowly until he was 12 years old, at which point its growth appeared to increase dramatically. Computerized tomography revealed an enlargement of the frontal and ethmoidal sinuses, with marked deformation of the anterior wall and of the roof of the left frontal sinus, as well as the roof of the ethmoid and upper sinus medial orbital wall. The sinus walls were of normal thickness. Access was via a bicoronal incision and osteotomy of the deformed fronto-orbital bossing. Reconstruction was undertaken with a periosteal flap and hydroxyapatite bone cement (Norian R ) following sinus mucosal stripping and obliteration of the sinus with fat. Six months postoperatively, the patient was without recurrence and had a good cosmetic result. Copyright 2002 European Association for Cranio-Maxillofacial Surgery. Published by Elsevier Science Ltd. All rights reserved.

The MAGALI chip is a 65nm digital baseband dedicated to advanced telecommunication applications. Based on a 15-router mesh Network-on-Chip - NoC, it embeds 22 Processing Elements - PE performing the different functions of a complex baseband in a programmable manner. The NoC framework is based on asynchronous routers which provide a complete Globally Asynchronous Locally Synchronous -- GALS framework. Thanks to this structure, each PE is a synchronous island with a programmable frequency. On the architectural side, the NoC supports fast reconfiguration thanks to a distributed scheme. In this demonstration, we propose to show the reconfiguration capabilities of the MAGALI chip on three modes of a 3GPP-LTE receiver part, by switching on-the-fly between these three modes. The resulting transmission quality with different levels of upcoming signal noises is shown.