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1. P673Improvement of arterial stiffness and myocardial deformation in patients with poorly controlled diabetes mellitus type 2 after optimization of antidiabetic medicationP674Clinical presentation, echocardiographic findings and complications in patients with typical and atypical form of takotsubo cardiomyopathyP675Left ventricular mass/end-diastolic volume ratio with tridimensional echocardiography in newly-diagnosed hypertensive patients: which relation between left ventricular geometry and stroke volume?P676Endothelial dysfunction: the link between arterial hypertension, diabetes mellitus and heart diseaseP677Dynamic of changes of arterial stiffness evaluated by cardio-ankle vascular index(CAVI) during the growth and development of children and adolescentsP678Peripheral arterial stiffness in pulmonary hypertension and pulmonary embolism: assessment with cardio ankle vascular index, noninvasive markers of vascular diseaseP679Early detection and prediction of CHOP-induced cardiotoxicity in nonHodgkin lymphoma by 4D echocardiography, vascular ultrasound, and cardiac biomarkersP680Right ventricular remodeling in children engaged in endurance sports: a longitudinal study in preadolescent athletesP681Electrocardiographic criteria for atria enlargement are not useful in the evaluation of junior high-dynamic high-static athletesP682Prognostic value of right ventricle, pulmonary arterial pressure and biomarkers in patients with acute heart failure: one year follow upP683One-point carotid stiffness parameters by echo-tracking method in a wide-age range of healthy population. A single center experienceP684Role of bidimensional speckle tracking longitudinal strain in the evaluation of right and left ventricular function in adult patients with transposition of the great arteriesP685Interfaces between FBN1 gene polymorphism and biomechanical parameters estimated by speckle-tracking echocardiography of dilative pathology of ascending aorta P686Layer-specific speckle tracking analysis for the detection of coronary artery disease during dipyridamole stress echoP687Stress echo in Italy: state-of-the art 2015P688The declining frequency of Inducible myocardial ischemia during stress echocardiography over 27 consecutive years (1983-2009)P689Global longitudinal strain can unmask inducible myocardial ischemia at submaximal heart rate during dobutamine stress echocardiography.P690Low risk syntax score predicted by wall motion score index during dobutamine stress echocardiographyP691Outdoor stress echo by lung ultrasound for subclinical detection of high altitude pulmonary edema with B-linesP692Predictors and consequences of infective endocarditis with perivalvular extension - a subgroup with worse short and medium-term prognosisP693Analysis of left atrial auricle morphology and function to detect considerable risk factors regarding the prevention of strokeP694LAA closure - does size really matter?P695Real assessment of mitral regurgitation by three-dimensional transesophageal echocardiographyP696Myocardial contrast dobutamine stress echocardiography for detection of coronary artery disease

Author: O. Tereshina, G. Perea, JM. Ribeiro, S. Stoebe, M. Coutinho Cruz, L. Pratali, HA. Zainal Abidin, CM. Van De Heyning, C. Carpeggiani, Q. Ciampi, M. Cameli, M. Bieseviciene, AT. Timoteo, O. Vriz, M. Deljanin Ilic, M. Konopka, F. D'ascenzi, D. Mihalcea, FL. Ciciarello, T. Jurko, A-M Vintila, M. Lembo, M. Budnik, I. Ikonomidis, G. Pavlidis, V. Lambadiari, F. Kousathana, H. Triantafyllidi, M. Varoudi, D. Vlastos, S. Vlachos, G. Dimitriadis, J. Lekakis, J. Kochanowski, R. Piatkowski, K. Wojtera, G. Opolski, F. Lo Iudice, R. Esposito, C. Santoro, D. Gerardi, G. De Simone, B. Trimarco, M. Galderisi, V. Vintila, I. Bruckner, AJR Jurko, A. Jurko, M. Mestanik, A. Mestanikova, I. Tonhajzerova, VS. Valeria Silvestri, RB. Roberto Badagliacca, DV. Dario Vizza, FF. Francesco Fedele, LA. Luciano Agati, M. Florescu, AM. Vladareanu, D. Vinereanu, M. Solari, BM. Natali, A. Malandrino, F. Valentini, M. Focardi, M. Bonifazi, A. Pelliccia, S. Mondillo, K. Burkhard-Jagodzinska, A. Jakubiak, W. Krol, A. Klusiewicz, R. Zdanowicz, D. Sitkowski, M. Dluzniewski, W. Braksator, D. Petrovic, S. Stojanovic, S. Ilic, G. Kocic, M. Pirisi, J. Magne, V. Aboyans, R. Minisini, E. Bossone, L. Moura Branco, SA. Rosa, A. Galrinho, L. Sousa, JA. Oliveira, A. Agapito, RC. Ferreira, V. Mizariene, JJ. Vaskelyte, V. Lesauskaite, R. Sepetiene, GE. Mandoli, D. Menci, E. Capitani, C. Albizzi, F. Crudele, R. Citro, S. Severino, G. Labanti, L. Cortigiani, R. Sicari, P. Colonna, E. Picano, P. Landi, C. Michelassi, B. Ectors, H. Heuten, B. Shivalkar, JOHAN Ismail, SAZZLI Kasim, G. Giardini, M. Cavana, R. Ilhao Moreira, L. Coutinho Miranda, J. Abreu, P. Modas Daniel, J. Fragata, R. Cruz Ferreira, G. Farese, A. Tarr, D. Jurisch, D. Pfeiffer, A. Hagendorff, R. Teixeira, L. Puga, M. Costa, J. Silva, L. Paiva, L. Goncalves, M. Lombardero, R. Henquin, C. Izurieta, and MC. Corneli
Subjects: medicine.medical_specialty, Aorta, business.industry, Diastole, General Medicine, Type 2 diabetes, medicine.disease, Blood pressure, medicine.artery, Internal medicine, medicine, Cardiology, Arterial stiffness, Radiology, Nuclear Medicine and imaging, Systole, Brachial artery, Cardiology and Cardiovascular Medicine, business, Pulse wave velocity
Abstract: Background Arterial stiffness is associated with increased risk for cardiovascular disease. The purpose of this study is to investigate the arterial stiffness and myocardial deformation in patients with poorly controlled diabetes mellitus type 2 before and after glycemic control by optimal medication. Methods In 50 patients with uncontrolled type 2 diabetes(age:52±10years)and 25 controls of similar age and sex and no atherosclerotic risk factors we measured at baseline and 6 months after glycemic control a) carotid-femoral pulse wave velocity(PWVc m/sec-Complior SP ALAM),central systolic blood pressure(cSBP -mmHg),augmentation index(AI%), of the aortic pulse wave(ArteriographTensioMed) b)S',E'(m/sec)andE'/A'of mitral annulus by Tissue Doppler c)LV longitudinal strain(GLS-%),systolic(LongSr-l/sec)and diastolic(LongSrE-l/sec)strain rate, twisting(Tw-deg),peak twisting(Tw)and untwisting(unTw-deg/sec)velocity using speckle tracking echocardiography.The degree of LV untwisting was calculated as the percentage difference between peak twisting and untwisting at MVO(%dp PeakTw-UntwMVO)and between peak twisting and untwisting at peak and end of the mitral inflow E wave d)perfusion boundary region(PBR- micrometers)of the sublingual arterial microvessels(ranged from 5-25 micrometers)using Sideview,Darkfield imaging(Microscan,Glycocheck).Increased PBR is considered an accurate index of reduced endothelial glucocalyx thickness because of a deeper RBC penetration in the glucocalyx e) Flow mediated dilatation(FMD) of the brachial artery and percentage difference of FMD (FMD%). Results Compared to controls,diabetics had higher PWVa(10.3±2.2 vs. 8.1±1.9), AI(27.9±15 vs. 19.4±14.7), PWVc(11.8±3.2 vs. 8.8±1.3),cSBP(136±20 vs. 119±18),PBR (2.1±0.2 vs 1.89±0.1)and lower GLS(-15±3 vs. -18±3),LongSr(-0.78±0.1 vs. -0.96±0.2),LongSrE(0.77±0.29 vs. 1.2±0.3),S',E' and E/A(p
Published: 2016
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2. Quality of Anticoagulation Control in Preventing Adverse Events in Patients With Heart Failure in Sinus Rhythm

Author: S. Shaw, Conrado J. Estol, Biykem Bozkurt, B. Donelly, R. Berkowitz, L. Berente, M. Jurczok, J. Simon, Sami Khella, A. Travis, M. Schoenauer, Ronald S. Freudenberger, Anikó Ilona Nagy, G. Marcinek, M. Hajkova, T. Siebert, R. Breedveld, W. Baker, P. Avellana, S. Kozhukhov, M. Diek, J. Jaros, R. Vicari, S. Timar, C. Schanz, J. Povolny, M. van Zagten, Shelley Zieroth, G. Rex, M. Apelian, M. Dzaiy, K. Hayward, A. Warner, L. Baliko, Piotr Ponikowski, S. Mathus, Arthur J. Labovitz, C. DeMers, E. Péterfai, Mariana Bolos, B. Stephens, F. Tito, Denise L. Janosik, N. Molakala, J. Dizes, R. van der Loo, A. van Bujisen-Nutters, K. Wolf, S. Nawaz, A. Boguschewski, D. Ferguson, A. McPhail, M. Rohwedder, M. Malkowski, R. Prodhan, P. Miekus, R. Pellegrino, M. Rossi, Michelle Bierig, E. Wirkowski, Zbigniew Gaciong, F. Guerlloy, D. Chupka, O. Kovtun, M. Padour, D. Horak, Elly M.C.J. Wajon, J. Carda, P. Gregor, M. Tilem, P. Kosolcharoen, R. Wensel, V. Garman, N. Torok, B. Benczur, E. Peña, G. Moe, B.M. Massie, S. Slomiak, C. Benesch, V. Orlyk, K. Greenan, M. Ogorek, I. Jedlinski, Shun Kohsaka, R. Haynes, Z. Lorenc, M. Kuchar, R. Pauer, T. Dugan, A. Juszczak, T. Schrader, A. Henriquez, K. Toth, M. Varga, J. Herman, M. Lee, M. Dunaj, L. Krizova, M. Bonora, P. Loviska, D. Aubin, M. Kokles, J. D. Easton, J. Meschia, A. Bruno, Steven Goldman, S. Voigt, D. Malchik, A. Tierney, Demetrios J. Sahlas, N. Elzebroek, Richard J. Hobbs, M. Charlet, B. Hattler, L. Regos, Dennis Wolf, A. Peljto, C. Lindsey, R. Winkler, J. Arredondo, B. Oze, C. Schuler, D. Bruck, E. Jones, G. Torre, S. Nabhan, G. Mallis, Jindřich Špinar, W. Graettinger, A. Ruiz, N. Holwerda, R. Katz, J. Gonzalez, Christine Gerula, P. Jansky, H. V. Anderson, B. Krizova, Andreas König, M. Moussavian, M. Konarzewski, G. Jakab, M. Liston, Elizabeth O. Ofili, L. Nikolaidis, Susan E. Ammon, Rebekka K. Schneider, M. Krauze-Wielicka, M. Zimmermann, J. Lynch, J. Minuk, F. Sokn, Douglas L. Mann, R. Sawyer, J. Partridge, D. Leifer, M. Bohdanowicz-Zazula, D. Barratt, C. Dewar, S. Kolomiets, T. Noonan, D. Beran, M. Jeserich, J. Wong, R. Bessoudo, M. Lichtenberger, E. Bednarova, R. Serafin, M. Scullin, I. Kosa, M. Hranai, E. Duverger, L. Joseph, A. M. Sindilar, I. Edes, E. Yakimenko, J. Hobbs-Williams, F. Novoa, A. Szczepanska, R. Wachter, P. A. de Milliano, L. Golan, Gregory W. Albers, K. Ammerman, Alexandra R. Sanford, W. Burgin, A. Richmond, A. Kleinrok, B. Dandapani, Laurie Gutmann, M. Houra, Udho Thadani, P. Schygiel, A. van Hessen, Christian Weber, S. Mehešová, P. Stein-Beal, E. Flanagan, R. Khadouri, P. Chang, Thomas P. Cappola, L. Konczarek, B. Mangariello, L. Atkins, C. McKay, J. Svoboda, O. Lesniak, L. Westbrook, S. J. Kim, C. Moy, M. Kuch, M. Nemec, M. Krobot, B. Kozlowski, M. Applegate, M. Kiorwantsi, J. Thierer, K. Craig, A. Slim, Y. Besaga, R. Kuba, P. Fulop, K. Crotto, R. Porcile, E. Falgout, E. Olgren, K. Kuc, Marcus F. Stoddard, W. Almeida, L. Pas, L. Williams, I. Sorokina, J. Rodl, S. Sparr, A. Coppes, E. Ronner, A. Jurczyk, S. Gass, John R. Teerlink, P. Kucera, H. J. Barnett, B. McGinnis, L. Wilson, Y. Tutov, R. MacFadyen, Gregory Y.H. Lip, V. Sorrell, T. Ochalek, J. Turner, M. Modzelewski, Matthew Wilson, A. Ogorodnichuk, C. Anderson, P. de Kort, B. Palossy, Alan B. Miller, T. Giles, H. Brown, Andrew H. Baker, P. Czaja, Roman Szełemej, J. Hanna, P. Gilbert, A. Metcalf, R. Piotrowski, D. Yip, B. Coull, P. Gitelman, Burkert Pieske, C. Rapallo, M. Morgil, M. Resch, A. Zachar, Jan Biegus, W. Watson, J. A. Hinchey, E. Polland, L. Caufield, D. Kopcik, E. Pechackova, M. Calderon, Stefan D. Anker, V. Virkud, R. Rothbart, L. Rudenko, W. Wicha, B. Jacques, Susan Graham, J. Donaldson, O. Girina, L. Guillory, S. Khoury, I. Padourova, Haissam Haddad, L. Kowalczyk, J. A. Swain, G. Prokop-Lewicka, R. Mattessich, K. Remmel, S. Tikhonova, S. Klochkov, J. Leppo, K. C. Johnston, D. Gohs, Peter K. Smith, Eric E. Smith, V. Hart, J. Vanyi, L. Voronkov, G. Allam, M. Klapholz, T. Varadyova, S. Daugherty, L. Witkin, K. Panizzon, B. Drachman, S. Locke, Ann‐Katrin Mojica Munoz, J. Love, T. Winder, P. Bailey, T. Huynh, G. A. Verheul, Tomasz J. Pasierski, J. Borbola, R. Liu, A. Elizalde, C. Walker, R. Kelley, Robert Côté, P. Frey, J. McGee, Peter E. Carson, T. Bator, Donald L. Patrick, K. Karsay, J. Plomp, O. Novikova, J. Vuijsters, Jay P. Mohr, A. Parkhomenko, A. Ducharme, C. Alteri, S. Borden, Siqin Ye, W. Felton, K. Peterson, M. Satori, N. Polenova, D. Karia, G. Turhan, R. Nagy, K. Amosova, J. Michalska, R. Libman, E. Frey, O. Najmanova, R. Yufe, O. Montaña, S. Bailey, M. Bodi, A. Ellis, J. Tarchalski, L. Sitwell, M. Del Valle, John P. Boehmer, J. Marler, P. Romia, K. Tea, E. Hartmann, R. Lebedova, V. Yurlov, O. Karpenko, Malcolm Arnold, P. Berkowski, J. Johnson, P. Ramappa, R. Ferkl, Dirk J. Lok, N. Bayer, S. Bezucha, A. Mercando, H. Tworek, R. Longaker, P. Jinkins, J. Kirmani, L. Svoboda, David Spence, Min Qian, John L.P. Thompson, N. Brodi, Y. Prokopovych, Sedat Sen, M. Nanna, S. T. Palmeri, M. Michalova, L. Giron, K. Wolkowska, D. Borts, K. Hamroui, G. Linssen, L. Arcement, A. McNulty, C. Jakobs, F. Bleyer, W. Lo, J. Bisognano, J. Kosits, Steven R. Levine, G. Berry, P. Heidrich, G. Kiss, G. Tullio, J. Yasen, G. Ortiz, B. O'Hare, P. Jackson, T. Rennie, Z. Davidovits, G. v Buchem-Damming, H. Dvorakova, W. Hermans, Zbigniew Kalarus, H. Morgil, C. Harris, M. Vissiennon, Shunichi Homma, André P. Gabriel, J. Aiub, I. Katzan, C. Zaidman, S. Sassone, A. Duszanska, J. Litvinova, P. Kralicek, M. Natour, E. Nagy, E. Nishime, M. J. Bos, S. Nowakowska, J. Beebe, B. Watson, N. Jacek, Ralph L. Sacco, A. Cwynar, S. Pezzella, B. George, B. Hott, T. Vegh, V. Mejia, E. Janzen, M. Eliasziw, Heribert Schunkert, L. Swydan, J. Gora, D. Drazek, C. Landau, L. Roffidal, L. Casazza, Andrew M Penn, Richard L. Hughes, V. Schumann, R. Santi, I. Sakharchuk, A. Adler, D. Taylor, C. F. Peerenboom-Fey, M. Dluzniewski, L. Cape, Attila Kovacs, E. Ziekenhuis, A. Bujdoso, L. Fischer, Richard Buchsbaum, Petr Arenberger, L. Pollak, J. Vosmerova, B. Donley, Patrick M. Pullicino, B. Darrow, A. Minagar, N. Jarmukli, J. Dissin, M. Daniels, L. Csuros, G. J. del Zoppo, E. Anthony, B. Metzkier-Wyrwa, A. Ronaszeki, I. Malek, R. Arbing, Gilberto Levy, D. Mauceri, Carlos J. Rodriguez, V. Kovalenko, J. Smith, O. Yaremenko, R. de Graaf Gasthuis, C. Donato, L. Spinarova, Martin M. Brown, F. Padour, O. Lovasz, Marco R. Di Tullio, K. Balaban, S. Donovan, S. Genth-Zotz, M. Maruskova, I. Varga, T. Drasnar, V. Berchou, R. Davies, Robert G. Hart, M. Lebedynska, G. Hageman, D. Disantis, W. Schneider, M. Frankel, A. Hajnalne, S. Baumann, P. Karpati, L. C. Pettigrew, Johnston Grier, A. Ellenberg, Bruce Levin, and Stephanie Hope Dunlap
Subjects: Intracerebral hemorrhage, medicine.medical_specialty, Aspirin, Ejection fraction, business.industry, Warfarin, 030204 cardiovascular system & hematology, medicine.disease, 3. Good health, Surgery, 03 medical and health sciences, 0302 clinical medicine, Interquartile range, Heart failure, Internal medicine, medicine, Cardiology, Sinus rhythm, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, business, Stroke, medicine.drug
Abstract: Background— The aim of this study is to examine the relationship between time in the therapeutic range (TTR) and clinical outcomes in heart failure patients in sinus rhythm treated with warfarin. Methods and Results— We used data from the Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) trial to assess the relationship of TTR with the WARCEF primary outcome (ischemic stroke, intracerebral hemorrhage, or death), with death alone, ischemic stroke alone, major hemorrhage alone, and net clinical benefit (primary outcome and major hemorrhage combined). Multivariable Cox models were used to examine how the event risk changed with TTR and to compare the high TTR, low TTR, and aspirin-treated patients, with TTR being treated as a time-dependent covariate. A total of 2217 patients were included in the analyses; among whom 1067 were randomized to warfarin and 1150 were randomized to aspirin. The median (interquartile range) follow-up duration was 3.6 (2.0–5.0) years. Mean (±SD) age was 61±11.3 years, with 80% being men. The mean (±SD) TTR was 57% (±28.5%). Increasing TTR was significantly associated with reduction in primary outcome (adjusted P P =0.001), and improved net clinical benefit (adjusted P P =0.082 for ischemic stroke and adjusted P =0.109 for major hemorrhage). Conclusions— In patients with heart failure in sinus rhythm, increasing TTR is associated with better outcome and improved net clinical benefit. Patients in whom good quality anticoagulation can be achieved may benefit from the use of anticoagulants. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00041938.
Published: 2015
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3. Club 35 Poster session 2: Thursday 4 December 2014, 08:30-18:00 * Location: Poster area

Author: M. Santos, J. Rivero, S. Mccullough, A. Opotowsky, A. Waxman, D. Systrom, A. Shah, C. Santoro, R. Esposito, V. Schiano Lomoriello, R. Raia, D. De Palma, R. Ippolito, P. Ierano, G. Arpino, G. De Simone, M. Galderisi, M. Cameli, M. Lisi, C. Di Tommaso, M. Solari, M. Focardi, M. Maccherini, M. Henein, S. Mondillo, I. Simova, T. Katova, B. Pauncheva, A. Vrettos, D. Dawson, C. Grigoratos, C. Papapolychroniou, P. Nihoyannopoulos, D. Voilliot, O. Huttin, T. Vaugrenard, C. Venner, N. Sadoul, E. Aliot, Y. Juilliere, C. Selton-Suty, I. Hamdi, H. Mahfoudhi, N. Ben Mansour, R. Dahmani, D. Lahidheb, W. Fehri, H. Haouala, H. Erken Pamukcu, D. Gerede, M. Sorgun, C. Akbostanci, S. Turhan, u. Erol, J. Magne, R. Dulgheru, S. Kou, C. Henri, L. Caballero, C. De Sousa, M. Sprynger, L. Pierard, P. Lancellotti, M. L. Panelo, A. Rodriguez-Fernandez, S. Escriba-Bori, W. Krol, M. Konopka, K. Burkhard, I. Jedrzejewska, A. Pokrywka, A. Klusiewicz, J. Chwalbinska, M. Dluzniewski, W. Braksator, A. Elmissiri, M. Eid, I. Sayed, H. Awadalla, V. Schiano-Lomoriello, F. Lo Iudice, P. Ibrahimi, F. Jashari, E. Johansson, C. Gronlund, G. Bajraktari, P. Wester, R. Potluri, A. Aziz, J. Hooper, S. Mummadi, H. Uppal, O. Asghar, S. Chandran, E. A. Surkova, O. V. Tereshina, U. V. Shchukin, A. O. Rubanenko, E. A. Medvedeva, L. Krapf, V. Nguyen, C. Cimadevilla, D. Himbert, E. Brochet, B. Iung, A. Vahanian, D. Messika-Zeitoun, C. M. Van De Heyning, P. Bruyere, L. Davin, C. De Maeyer, B. Paelinck, C. Vrints, P. Bertrand, Y. Groenendaels, V. Vertessen, W. Mullens, M. Pettinari, H. Gutermann, R. Dion, D. Verhaert, P. Vandervoort, S. Guven, T. Sen, O. Tufekcioglu, E. Gucuk, B. Uygur, E. Kahraman, Z. Valuckiene, R. Jurkevicius, R. Pranevicius, J. Marcinkeviciene, D. Zaliaduonyte-Peksiene, N. Stoskute, and R. Zaliunas
Subjects: medicine.medical_specialty, business.industry, Thursday, Medicine, Radiology, Nuclear Medicine and imaging, Medical physics, General Medicine, Club, Radiology, Session (computer science), Cardiology and Cardiovascular Medicine, business
Published: 2014
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4. Moderated Posters session: pulmonary hypertension and other conditionsP516Echocardiographic findings predicting mortality in pulmonary arterial hypertension: a systematic review and meta-analysisP517Impairment of endothelial-mediated coronary flow reserve in patients with Anderson Fabry diseaseP518Comparative evaluation of various echocardiography-based methods for the estimation of pulmonary vascular resistance in pulmonary hypertensionP519Detection of early radiotherapy-induced changes in myocardial cyclic variation in breast cancer patients - an ultrasound tissue characterization studyP520Right ventricle adaptation changes resulting from endurance training in the group of junior cyclists - sex is an important determinantP521Impact of pulmonary hypertension on the impairment of right ventricular longitudinal function in patients with obstructive sleep apnea syndromeP522Improvement of echocardiographic (TTE) estimation of pulmonary vascular resistance (PVR) in comparison with right heart catheter measurementsP523Assessment of left ventricular function in breast cancer patients with adjuvant treatment (combined anthracyclines and trastuzumab): two years follow upP5243D regional right ventricular function in pulmonary hypertensionP525Simple echocardiographic parameters to assess right ventricular systolic function in patients with precapillary pulmonary hypertension: a comparison with cardiac magnetic resonance imaging

Author: M L Handoko, N Duchateau, I Krstic, S Wahi, C Santoro, M Konopka, S Tuohinen, C Venner, L Spinelli, VJM Baggen, MMP Driessen, MC Post, AP Van Dijk, JW Roos-Hesselink, AE Van Den Bosch, JJM Takkenberg, GT Sieswerda, C A Giudice, D Castaldo, A Pisani, B Trimarco, O Huttin, D Mandry, D Voilliot, JF Chabot, PY Marie, Y Juilliere, A Chaouat, C Selton-Suty, T Skytta, V Virtanen, PL Kellokumpu-Lehtinen, P Raatikainen, K Burkhard-Jagodzinska, W Krol, R Zdanowicz, M Starczewski, K Aniol-Strzyzewska, A Jakubiak, D Sitkowski, M Dluzniewski, W Braksator, A Buonauro, ML Bocchino, R Esposito, A Canora, A Vaccaro, S Castaldo, A Sanduzzi Zamparelli, M Galderisi, A Chong, M Deljanin Ilic, S Vrbic, D Marinkovic, S Ilic, M Sermesant, P Gibelin, E Ferrari, P Moceri, MC Di Pasqua, OA Spruijt, FPT Oosterveer, JT Marcus, HJ Bogaard, and A Vonk Noordegraaf
Subjects: medicine.medical_specialty, Contraction (grammar), business.industry, Area strain, Severe disease, General Medicine, medicine.disease, Pulmonary hypertension, Nyha class, Surgery, medicine.anatomical_structure, Endurance training, Ventricle, Internal medicine, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, In patient, Cardiology and Cardiovascular Medicine, business
Abstract: Purpose: Pulmonary hypertension (PH) is a rare and severe disease for which right ventricular (RV) remodelling and function are associated with survival. The unique anatomy and structure of the RV limit 2D analysis, and its regional function has not been studied yet. We show the contribution of regional 3D deformation analysis for the study of RV remodelling in patients with PH, as compared to healthy controls. Methods: 3D RV echocardiographic sequences were prospectively obtained from 32 patients with PH (57±21y, 15 male) and 10 healthy controls (38±13y, 6 male). Myocardial tracking was performed by semi-automatic Tomtec 4D RV-Function 2.0 software. Volumes and EF were directly obtained from the software. Output RV meshes were post-processed to extract local deformation (area strain) and radial/circumferential/longitudinal displacement. Data were temporally realigned to allow inter-subject pattern comparison. Spatial correspondences were obtained from the software, and allowed statistical computation in 8 standard zones of the RV. Results: 19 patients (59%) were NYHA class III-IV at baseline. Over a mean FU of 49±41days, 5 patients died from cardiopulmonary causes. The highest contraction was at the RV lateral and inferior levels. Regional motion and deformation and global volume patterns for patients was significantly affected at the RV anterior, lateral, inferior, and trabecular and inlet septum. The first 4 segments were significantly associated with NYHA class and survival. Global area strain >-15% was a significant predictor of death (HR 411e12 [140 – 1.2e27]). Conclusion: Our study confirms that the segments into which RV contraction predominates are also the determinants of symptoms and survival in PH patients. This is of high relevance to establish the prognosis of such patients.
Published: 2015
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5. Poster session Wednesday 11 December all day display: 11/12/2013, 09:30-16:00 * Location: Poster area

Author: S. Bosi, K. Wierzbowska-Drabik, W. Mullens, C. Goh, M. Abdel Ghany, J. Monmeneu, M. Perez Guillen, B. Zaborska, A. Di Lenarda, H. Mueller, M. Dluzniewski, R. Del Pozo Contreras, E. Laraudogoitia Zaldumbide, S. Yurdakul, O. Bech-Hanssen, M. Fernandez Garcia, R. Ippolito, C. Torromeo, B. Popescu, M. Cameli, P. Gaudron, M. Salvetti, R. Amano, E. Osto, P. Cabeza Lainez, G. Generati, C.H. Attenhofer Jost, J. Rueda-Soriano, F. Negri, T. Zielinski, M. El Serafi, Y. Agmon, I. Losano, Y. Qin, I. Castiglione, G. Santambrogio, A. Farhati, P. Menasche, K. Wdowiak-Okrojek, R. Juneja, G. Di Sciascio, N. Gaibazzi, D. Shin, F. Romeo, O. Huttin, P. Puddu, I. Ikonomidis, T. Baran, G. Tinica, A. Bel Minguez, E. Erdogan, M. Herruzo Rojas, I. Ter Horst, J. Suarez De Lezo, P. Bertrand, B. Putnikovic, O. Kretschmar, M. Gigli, F. Scholz, M. Lainscak, O. Rifaie, E. Tahirovic, A. Svanadze, G. Makavos, L. Iliuta, L. G. T. Zacharias, M. Baldelli, A. Porto, C. Di Nora, O. Asghar, A. Ramalli, W. Krol, M. Ahmed Abdel-Rahman, R. Autschbach, R. Tripodi, A. Budaj, V. Velagic, J. Kurcz, J. Aguilar, V. V. Kochmasheva, O. Enescu, H. Triantafyllidi, J. Diago, J. Park, J. Breur, F. Tona, M. Cikes, C. Maurea, T. Edvardsen, B. Igual Munoz, B. Michalski, J. Separovic Hanzevacki, A. Hagege, L. Gullestad, P. Sogaard, T. Fritz-Hansen, M. Rosca, A. Kuch-Wocial, C. Gonzalez Canovas, H. Uyarel, M. Guazzi, E. Pigatto, M. Carminati, R. Soyka, P. Tortoli, D. Djordjevic-Radojkovic, D. De Palma, L. Yuan, E. Mazzotta, M. Henein, D. Botezatu, J. Feng, L. Casteilla, C. Vignati, I. Burazor, M. Krestjyaninov, E. Zhdanova, D. Milicic, H. Mahfoudhi, A. Aziz, P. Trivilou, R. Hoffmann, A. Mysiak, C. Martini, K. Haugaa, F J V M Francisco Jose Valera Martinez, J. Lessick, M. Maccherini, C. Olympios, D. Mutlak, B. Haugen, M. Martin, A. Santoro, A. Orda, B. Skoric, S. Mihaila, M. Jung, G. Leenders, A. Bozkurt, M. Greco, M. Muratori, A. Subinas Elorriaga, Z. Radunovic, A. Osa-Saez, Z. Suciu, M. Alloni, F. Alamanni, J. Choi, J. Schwartz, M. Mericskay, M. Gurzun, D. Leone, P. Omede, J. Sawicki, D. Saura Espin, E. W. Remme, M. Bando, M. Varoudi, J. Gonzalez Carrillo, G. F. Gjerdalen, S. Aakhus, T. Bombardini, F. Veglio, L. Baduena, A. Calin, B. Austin, C. Viacroze, S. Aytekin, C. Santoro, I. Benedek, S. Comenale Pinto, F. Verbrugge, G. Styczynski, M. Sunbul, N. Pandian, T. Forster, J. Hisdal, S. Mondillo, M. Mourali, L. Magda, A. Quesada-Carmona, E. Caiani, G. Pavlidis, S. Ojeda, W. Ding, S. Ramakrishnan, L. Stefanczyk, A. Voumbourakis, A. M. Maceira Gonzalez, B. Igual, C. Selton-Suty, O. B. Kerbikov, B. Karolko, P. Lipiec, F. Meijboom, T. Andersen, M. Pellegrino, M. Lopez-Lereu, J. Kasprzak, Y. Zhao, R. Lang, M. Valdés Chávarri, J. Muir, A. Goetzenich, J. Hooper, M. Driessen, M. Greutmann, S. Casablanca, V. Curci, P. Szymanski, M. Cramer, F. Tosello, C. Gronlund, M. Chiavarelli, A. Cuvelier, P. Mogutova, F. Bandera, G. Greil, P. Fernandez Garcia, E.R. Valsangiacomo Buechel, M. Sobczynska, M. Kennedy, S. Boitard, D. Voilliot, H. Bellsham-Revell, A. Casacalenda, M. Sata, P. J. Sanchez Millan, S. Nishio, C. Chrisochoou, S. Mirfeizi, C. Beladan, K. Steine, M. Lisi, N. Krylova, A. Vlahovic-Stipac, S. Carerj, A. Oxenius, B. Geloneze, R. Calabro, E. Occhetta, P. Caso, R. Massey, B. Cengiz, M. Palencia-Perez, X. Xu, S. Brili, A. Evangelista, D. Mesa, S. Abadi, V. Reskovic Luksic, G. De La Morena Valenzuela, M. Anzini, S. Iliceto, A. Saxena, D. Vinereanu, G. Ussia, M. Sikora-Frac, S. Censi, R. Razavi, T. Wakatsuki, M. Romero, L. Punzi, C. Stefanadis, M. Pepi, E. Chueca Gonzalez, D. Rea, R. Chistol, I. Michalowska, N. Hayes, J. D'hoge, H. Aloui, D. Verhaert, I. Lekuona Goya, O. Sklyanna, K. Taamallah, S. Urheim, B. Natali, G. Sieswerda, M. Casartelli, D. Czarnecka, K. Lagerstrand, T. Chamova, E. Solberg, L. Sabia, M. Vatankulu, M. Obremska, D. Stolfo, H. Haouala, G. Bajraktari, G. Oria Gonzalez, I. Tournev, N. Olsen, O. R. Coelho, F. Spano, J. Yip, M. Anastasiou-Nana, A. Montero Argudo, S. Poli, J.-M. Sellal, P. Kulakowski, K. Kawecka-Jaszcz, O. Sonmez, M. Merlo, A. Chiru, A. Moreo, A. Colombo, R. Dahmani, W. Fehri, V. Rameev, D. Liu, A. Olszanecka, G. Placha, N. Kouris, A. Zaroui, J. Ljubas, G. Famoso, A. Massoni, S. Gao, M. Delgado, I Rodriguez Sanchez, R. Vazquez Garcia, D. Peluso, V. Planat-Benard, J. Cosin-Sales, E. Avenatti, V. Karidas, G. Sinagra, B. Jako, E. Alfonzetti, C. Hernandez Acuna, H. Farouk, D. Foley, M. Chmiela, P. Gripari, G. Patti, J. C. Pareja, Y. Hwang, C. Polte, D. Damaskos, D. Aronson, T. Rechcinski, T. Soeki, D. Simon, D. Anderson, N. Maurea, A. Brunet, C. Florescu, M. Marchei, A. Safarova, F. Cozzi, A. Neskovic, S. Mega, V. Miro-Palau, K. Darahim, B. Bednarz, A. Bitto, F. De Stefano, E. Kostarska-Srokosz, A. Nemes, G. Vizzari, T. Leiner, N. E. Hasselberg, P. Maffei, F. Mezni, Z. Bogdanovic, S. Kul, W. Kosmala, M. Rivero-Ayerza, G. Piscopo, M. Schiariti, V. Cammalleri, V. Kostopoulos, S. Storve, S. Stoerk, I. Planinc, B. Mutlu, J. R. M. Souza, J. J. Onaindia Gandarias, V. Donghi, H. Hamdi, G. Bagadur, A. Mabrouk Salem Omar, M. Floria, A. Klisiewicz, G. Barbati, A. Akhundova, A. Cacicedo, M. Annabi, D. Domingo-Valero, J. Simpson, J. Suarez De Lezo Herreros De Tejada, F. Cesana, D. Sergi, G. Alongi, M. Coppola, L. Grieten, G. Woo, L. Badano, G. Ertl, L. Caballero Jimenez, E. Donal, A. Kalapos, A. Anna Klisiewicz, H. Duengen, F. Mazuelos, U. Aguirre Larracoechea, N. Hasselberg, P. Domsik, L. Fusini, Z. Rezine, M. Misailidou, M. Rodriguez Serrano, D. Waterhouse, K. Keramida, F. Procaccio, G. Dell'era, N. Popova, F. Musumeci, D. Presutti, S F de Marchi, J. Van 'T Sant, S. Moisseyev, K. Paraskevopoulos, L. Molano, J. Estornell Erill, M. Gaspari, Z. Kobalava, I. Jedrzejewska, M. Galderisi, S. Neubauer, Piotr Hoffman, U. Cucchini, O. Miller, W. Kong, A. Swiatowiec, M. Vrolix, C. Grattoni, K. Broch, P. Ibrahimi, M. Garcia Navarro, R. Sheahan, P. Hoffman, M. Boratynska, J. Castillo Ortiz, R. Jankovic-Tomasevic, S. Wijers, P. Lindqvist, C. Tiu, V De Francesco, C. Goffredo, P. Agostoni, H. Yamada, V. Varano, T. Al-Maimoony, P. Wester, P. Schoof, J. Son, P. Piotr Szymanski, F. Righini, O. Agbulut, P. Nardinocchi, A. Aljalloud, I. Stankovic, O. A. Smiseth, L. Halmai, A. Bacaksiz, S. Rayasamudra, D. Filipiak, D. Muraru, D. Zysko, S. Muscoli, O. Goktekin, M. Przewlocka-Kosmala, S. Ryu, Z. Baricevic, M. Meine, J. Monmeneu Menadas, L. Gheorghe, A. Cremonesi, M. Lipczynska, A. Chaim, M. K. Smedsrud, M.D. Espinosa García, S. Mbarki, I. Stamatopoulos, L. Ling, F. Jashari, Y. Juilliere, D. Lahidheb, B. Mcadam, B. Bijnens, B. Pezo Nikolic, V. Guergueltcheva, J.-P. Vallee, O. Erdogan, R. Muscariiello, R. Mincu, M. Deljanin Ilic, C. Coppola, F. Arenga, J. Walker, M. Bono, J. Segura, R. Mechmeche, H. Uppal, S. Hayashi, A. Alhadad, M. Klinger, S. Herrmann, S. Snare, J. Estornell, M. Grecu, L. Lukasz Mazurkiewicz, J. Hotchi, C. Cipresso, E. Esposito, T. Marwick, N. Poteshkina, C. Zito, A. Squeri, V. Razin, I. Paraskevaidis, M. Jemaa, R. Marcun, R. Potluri, A. Anton Ladislao, F. Buendia-Fuentes, M. Pavlovic, S. Salinger-Martinovic, B. Igual-Munoz, T. Seoane, K. Mischke, G. Tamborini, G. Kim, A. Kardos, G. Pizzino, C. Matei, N. Hatam, V. P. Dityatev, H. Torp, A. Degiovanni, F. Rigo, M. Janulewicz, M. Gospodinova, M. Pan, P. Vallerio, F. Gaita, X. Jin, M. Akkaya, B. Pinamonti, A. Javanbakht, B. Lamia, N. A. Yaroshchuk, L. Musial-Bright, W. J. Nadruz, I. Papadakis, G. Kunszt, Y. Hirata, A. Shim, P. Maciejewski, M. Oliva Sandoval, S. Kadivec, E. Pilichowska-Paszkiet, F. Ranocchi, H. Neametalla, K. Hu, I. Sari, F. Carrasco, R. Ancona, R. Weber, R. Ivanova, A. Bartorelli, K. Eskesen, L. Teresi, P. Lopez Lereu, A. Holmgren, M. Kosnik, M. Turfan, M. Sobieszczanska-Malek, E. Kongsgaard, A. Bell, G. Hong, S. Denchev, A. Tasal, D. Mihalcea, F. Weidemann, G. De Caridi, A. Haggui, N. Hajlaoui, P. Alonso-Fernandez, A. Quattrone, M. Massetti, W. Braksator, I. Lekakis, T. Sahin, S. Carasso, F. Dassie, C. Bucca, C. Ginghina, C. A. Szmigielski, J. Baran, Z. Li, E. Aliot, A. Milan, J. Farkas, C. Smeets, D. Stanojevic, H. Dalen, S. Apostolovic, C. Moretti, G. Bruno, X. Zhao, E. Christoforatou, C. Arra, H. Poorzand, J. Ruvira, R. Matasic, F. Maffessanti, T. Vaugrenard, E. Szymczyk, R. Gimaev, S. Tellatin, C. Magnino, S. Velasco Del Castillo, P. Vandervoort, P. Doevendans, A. Dragan, M. Florescu, D. Carballo, P. Marino, D. Lovric, J. Nilson, L. Tong, H. Khorshid, R. Enache, A. Ruck, T. Benedek, R. Winter, M. Ruiz Ortiz, and E. Johansson
Subjects: medicine.medical_specialty, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Medical physics, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business
Published: 2013
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6. Club 35 Poster Session Wednesday 5 December * Right ventricular systolic function

Author: T. Hugues, V. Lacroix-Hugues, K. Yaici, P. Gibelin, I. Cabrita, S. Pires, A. Nunes, C. Sousa, N. Cortez-Dias, F. Pinto, A. Hrynkiewicz-Szymanska, W. Braksator, F. Szymanski, M. Chmielewski, M. Dluzniewski, P. Alonso Fernandez, A. Andres Lahuerta, V. Miro Palau, F. Buendia Fuentes, B. Igual Munoz, A. Osa Saez, A. Quesada Carmona, D. Tejada Ponce, B. Munoz, A. Salvador Sanz, S. Imamura, K. H. Hirata, T. Kubo, M. Orii, T. Tanimono, K. Takemoto, Y. Ino, T. Yamaguchi, T. Imanishi, T. Akasaka, T. Kinoshita, T. Asai, T. Suzuki, M. Krestjyaninov, V. Ruzov, T. Tanimoto, T. Yamano, G. Junca Puig, E. F. Sistach, L. Delgado Ramis, J. Lopez Ayerbe, N. Vallejo Camazon, f. Gual Capllonch, A. Teis Soley, M. Camara Rosell, X. Ruyra Baliarda, A. Bayes-Genis, P. Alonso fernandez, A. Maceira Gonzalez, C. Hernandez, A. Bel Minguez, B. Munoz Igual, A. Montero Argudo, S. Antit, S. fennira, I. Zairi, S. Kamoun, S. Kraiem, A. Matsuyama, C. Van De Heyning, J. Magne, L. Pierard, L. Davin, P. Bruyere, C. De Maeyer, B. Paelinck, C. Vrints, P. Lancellotti, J. Wang, f. fang, M. Liu, Y. Liang, C. Yu, Y. Lam, C. Kenny, M. Monaghan, S. Ercan, S. Kervancioglu, V. Davutoglu, M. Cakici, A. Ozkur, M. Oylumlu, I. Sari, A. Sikora-Puz, M. Mizia, K. Gieszczyk-Strozik, K. Matyjaszczyk-Zbieg, M. Haberka, K. Mizia-Stec, Z. Gasior, S. Wos, M. Deja, M. Jasinski, O. Enescu, M. florescu, D. Mihalcea, R. Rimbas, M. Cinteza, and D. Vinereanu
Subjects: medicine.medical_specialty, business.industry, Physical therapy, medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Session (computer science), Systolic function, Club, Cardiology and Cardiovascular Medicine, business
Published: 2012
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7. Poster session II * Thursday 9 December 2010, 14:00-18:00

Author: P. A. Pabari, A. Kyriacou, M. Moraldo, B. Unsworth, R. Baruah, N. Sutaria, A. Hughes, J. Mayet, D. P. Francis, T. Uejima, K. Loboz, F. Antonini-Canterin, C. Polombo, S. Carerj, D. Vinereanu, A. Evangelista, G. Leftheriotis, A. G. Fraser, A. Kiotsekoglou, M. Govindan, S. C. Govind, S. K. Saha, A. J. Camm, P. M. Azcarate, S. Castano, M. Rodriguez-Manero, M. Arraiza, B. Levy, J. Barba, G. Rabago, G. Bastarrika, A. Nemes, R. Takacs, T. Varkonyi, H. Gavaller, I. Baczko, T. Forster, T. Wittmann, J. G. Papp, C. Lengyel, A. Varro, L. R. Tumasyan, K. G. Adamyan, O. Savu, T. Mieghem, P. Dekoninck, L. Gucciardo, R. Jurcut, S. Giusca, B. A. Popescu, C. Ginghina, J. Deprest, J. U. Voigt, M. Versiero, M. Galderisi, R. Esposito, A. Rapacciuolo, G. Esposito, R. Raia, T. Morgillo, F. Piscione, G. De Simone, M. A. Oraby, F. A. Maklady, E. M. Mohamed, A. Z. Eraki, D. Zaliaduonyte-Peksiene, E. Tamuleviciute, J. Janenaite, J. Marcinkeviciene, V. Mizariene, S. Bucyte, J. Vaskelyte, D. Trifunovic, I. Nedeljkovic, D. Popovic, M. Ostojic, B. Vujisic-Tesic, M. Petrovic, S. Stankovic, D. Sobic-Saranovic, M. Banovic, A. Dikic-Djordjevic, K. Savino, A. Lilli, E. Grikstaite, V. Giglio, E. Bordoni, G. Maragoni, C. Cavallini, G. Ambrosio, B. Jakovljevic, B. Beleslin, M. Nedeljkovic, O. Petrovic, S. Moral, J. Rodriguez-Palomares, M. Descalzo, G. Marti, V. Pineda, P. Mahia, L. Gutierrez, T. Gonzalez-Alujas, D. Garcia-Dorado, F. Schnell, E. Donal, C. Thebault, A. Bernard, H. Corbineau, H. Le Breton, J. Kochanowski, P. Scislo, R. Piatkowski, M. Roik, M. Marchel, D. Kosior, G. Opolski, A. M. Lesniak-Sobelga, E. Wicher-Muniak, M. Kostkiewicz, M. Olszowska, E. Suchon, P. Klimeczek, P. Banys, M. Pasowicz, W. Tracz, P. Podolec, A. Laynez, D. E. Hoefsten, B. B. Loegstrup, B. Norager, J. E. Moller, A. Flyvbjerg, K. Egstrup, W. Streb, M. Szulik, J. Nowak, E. Markowicz-Pawlus, A. Duszanska, A. Sedkowska, Z. Kalarus, T. Kukulski, L. Spinelli, C. Morisco, E. Assante Di Panzillo, F. Buono, S. Crispo, B. Trimarco, A. A. Hawary, G. M. Nasr, M. M. Fawzy, L. Faber, W. Scholtz, J. Boergermann, M. Wiemer, G. Kleikamp, N. Bogunovic, Z. Dimitriadis, J. Gummert, D. Hering, D. Horstkotte, F. Luca', S. Gelsomino, R. Lorusso, S. Caciolli, R. Carella, G. Bille', G. De Cicco, V. Pazzagli, G. F. Gensini, A. Borowiec, R. Dabrowski, J. Janas, A. Kraska, B. Firek, I. Kowalik, H. Szwed, K. A. Marcus, C. L. De Korte, T. Feuth, J. M. Thijssen, L. Kapusta, J. Dahl, L. Videbaek, M. K. Poulsen, P. A. Pellikka, K. Veien, L. I. Andersen, T. Haghfelt, M. Haberka, K. Mizia - Stec, T. Adamczyk, M. Mizia, A. Chmiel, P. Pysz, M. Sosnowski, Z. Gasior, M. Trusz - Gluza, M. Tendera, T. Niklewski, K. Wilczek, P. Chodor, T. Podolecki, A. Frycz-Kurek, M. Zembala, S. Yurdakul, O. Yildirimturk, Y. Tayyareci, K. Memic, I. C. C. Demiroglu, S. Aytekin, C. J. Garcia Alonso, E. Ferrer Sistach, L. Delgado, J. Lopez Ayerbe, N. Vallejo Camazon, F. Gual Capllonch, M. Espriu Simon, X. Ruyra, A. Caballero Parrilla, A. Bayes Genis, L. Lecuyer, A. Berrebi, E. Florens, M. Noghin, C. Huerre, P. Achouh, R. Zegdi, J. N. Fabiani, B. De Chiara, A. Moreo, F. Musca, F. De Marco, E. Lobiati, O. Belli, F. Mauri, S. Klugmann, A. Caballero, N. Vallejo, A. Gonzalez Guardia, R. Nunez Aragon, C. Bosch, E. Ferrer, M. L. Pedro Botet, F. Gual, M. Cusma-Piccione, C. Zito, G. Oreto, R. Giuffre, M. C. Todaro, C. M. Barbaro, S. Lanteri, C. Longordo, J. Salvia, A. Bensaid, R. Gallet, E. Fougeres, P. Lim, J. Nahum, J. F. Deux, P. Gueret, E. Teiger, J. L. Dubois-Rande, J. L. Monin, F. Behramoglu, Z. Colakoglu, V. Aytekin, C. Demiroglu, L. Gargani, E. Poggianti, R. Bucalo, M. Rizzo, F. Agrusta, P. Landi, R. Sicari, E. Picano, A. Sutandar, B. B. Siswanto, I. Irmalita, G. Harimurti, S. Y. Hayashi, M. M. Nascimento, B. Lindholm, B. Lind, A. Seeberger, M. A. Pachaly, M. C. Riella, A. Bjallmark, L. A. Brodin, L. Poanta, M. Porojan, D. L. Dumitrascu, I. Ikonomidis, S. Tzortzis, J. Lekakis, D. T. Kremastinos, I. Paraskevaidis, I. Andreadou, M. Nikolaou, P. Katsibri, M. Anastasiou-Nana, A. M. Maceira Gonzalez, C. Ripoll, J. Cosin-Sales, B. Igual, J. Salazar, V. Belloch, J. Cosin-Aguilar, D. J. Pennell, M. Masaki, J. N. Pulido, T. Yuasa, S. Gillespie, B. Afessa, D. R. Brown, S. V. Mankad, J. K. Oh, A. L. Gurghean, A. M. Mihailescu, I. Tudor, C. Homentcovschi, M. Muraru, I. V. Bruckner, C. E. Correia, B. Rodrigues, D. Moreira, L. F. Santos, P. Gama, O. Dionisio, C. Cabral, O. Santos, T. Bombardini, S. Gherardi, G. Arpesella, S. Valente, I. Calamai, E. Pasanisi, S. Sansoni, P. Szymanski, P. Dobrowolski, M. Lipczynska, A. Klisiewicz, P. Hoffman, D. Stepowski, B. Kurtz, G. Grezis-Soulie, A. Savoure, F. Anselme, F. Bauer, J. Castillo, N. Herszkowicz, C. Ferreira, A. Goscinska, K. Mizia-Stec, W. Poborski, O. Azevedo, I. Quelhas, J. Guardado, M. Fernandes, C. S. Miranda, P. Gaspar, A. Lourenco, R. Medeiros, J. Almeida, S. L Bennani, V. Algalarrondo, S. Dinanian, J. Guiader, C. Juin, D. Adams, M. S. Slama, J. J. Onaindia, O. Quintana, S. Velasco, E. Astigarraga, A. Cacicedo, J. Gonzalez, I. Rodriguez, M. Sadaba, M. Eneriz, E. Laraudogoitia Zaldumbide, I. Nunez-Gil, M. Luaces, J. Zamorano, J. C. Garcia Rubira, D. Vivas, B. Ibanez, P. Marcos Alberca, C. Fernandez Golfin, J. Alonso, C. Macaya, J. Silva Marques, A. G. Almeida, V. Carvalho, C. Jorge, D. Silva, M. Gato Varela, S. Martins, D. Brito, M. G. Lopes, E. Tripodi, B. Miserrafiti, V. Montemurro, R. Scali, P. Tripodi, A. Winkler, A. Madej, I. Hausmanowa-Petrusewicz, M. Fijalkowski, A. Koprowski, M. Jaguszewski, R. Galaska, M. Taszner, A. Rynkiewicz, R. Citro, F. Rigo, G. Provenza, Q. Ciampi, M. M. Patella, A. D'andrea, O. Vriz, C. Astarita, E. Bossone, F. Heggemann, T. H. Walter, T. H. Kaelsch, T. Sueselbeck, T. H. Papavassiliu, M. Borggrefe, D. Haghi, T. Monk-Hansen, C. Have Dall, S. Bisgaard Christensen, M. Snoer, F. Gustafsson, H. Rasmusen, E. Prescott, G. Finocchiaro, B. Pinamonti, M. Merlo, G. Barbati, A. Di Lenarda, R. Bussani, G. Sinagra, T. Butz, C. N. Lang, A. Meissner, G. Plehn, H. Yeni, C. Langer, H. J. Trappe, X. Gu, X. Y. Gu, Y. H. He, Z. A. Li, J. C. Han, J. Chen, P. Gaudron, M. Niemann, S. Herrmann, K. Hu, B. Bijnens, H. Hillenbrand, M. Beer, G. Ertl, F. Weidemann, A. Mazzone, M. Mariani, I. Foffa, A. Vianello, S. Del Ry, S. Bevilacqua, M. G. Andreassi, M. Glauber, S. Berti, M. Grabowski, M. Postula, A. Dragulescu, G. Van Arsdell, O. Al-Radi, C. Caldarone, L. Mertens, K. J. Lee, R. P. Casula, H. Yadav, A. Cherian, A. D. Hughes, A. Vitarelli, S. D'orazio, B. L. Nguyen, G. Iorio, D. Battaglia, F. Caranci, V. Padella, L. Capotosto, L. Alessandroni, F. Barilla, C. Cardin, S. Hascoet, M. Saudron, G. Caudron, B. Arnaudis, P. Acar, M. M. Sun, X. H. Shu, C. Z. Pan, X. Y. Fang, D. H. Kong, F. Fang, Q. Zhang, Y. S. Chan, J. M. Xie, W. K. Yip, Y. Y. Lam, J. E. Sanderson, C. M. Yu, M. Rosca, K. O' Connor, G. Romano, J. Magne, A. Calin, D. Muraru, L. Pierard, P. Lancellotti, A. Roushdy, I. Elfiky, G. El Shahid, A. Elfiky, M. El Sayed, K. Wierzbowska-Drabik, L. Chrzanowski, A. Kapusta, E. Plonska-Goscinak, M. Krzeminska-Pakula, M. Kurpesa, T. Rechcinski, E. Trzos, J. D. Kasprzak, M. K. Ersboll, N. Valeur, U. M. Mogensen, M. Andersen, C. Hassager, P. Sogaard, L. V. Kober, M. Kloeckner, D. Hayat, C. Dussault, N. Lellouche, N. Elbaz, A. Demopoulos, G. Hatzigeorgiou, E. Leontiades, A. Motsi, G. Karatasakis, G. Athanassopoulos, P. Zycinski, J. Kasprzak, M. C. Vazquez Alvarez, C. Medrano Lopez, M. Camino Lopez, S. Granja, J. L. Zunzunegui Martinez, E. Maroto Alvaro, W.-C. Tsai, J.-Y. Chen, Y.-W. Liu, C.-C. Lin, L.-M. Tsai, D. C. Gomes, S. Robalo Martins, M. R. Gois, S. Ribeiro, A. Nunes Diogo, P. Sengupta, G. Di Bella, G. Caracciolo, S. Lentini, E. Kinova, N. Zlatareva, A. Goudev, N. Papagiannis, M. Mpouki, A. Papagianni, M. Vorria, G. Mpenetos, D. Lytra, E. Papadopoulou, P. Sgourakis, J. Malakos, J. Kyriazis, V. Kodali, R. Toole, A. S. Gopal, J. Celutkiene, A. Rudys, V. Grabauskiene, S. Glaveckaite, E. Sadauskiene, Z. Lileikiene, N. Bickauskaite, E. Ciburiene, V. Skorniakov, A. Laucevicius, C. H. Attenhofer Jost, M. Pfyffer, R. Lindquist, J. L. F. Santos, O. R. C. Coelho, C. M. Mady, M. H. P. Picard, V. M. C. Salemi, L. Funk, M. W. Prull, J.-Y. Shih, Y.-Y. Huang, K. O'connor, M. Moonen, L. A. Pierard, D. C. Cozma, C. Mornos, A. Ionac, L. Petrescu, D. Dragulescu, R. Dan, I. Popescu, S. I. Dragulescu, T. G. Von Lueder, A. Hodt, G. F. Gjerdalen, T. E. Andersen, E. E. Solberg, K. Steine, T. Van Mieghem, M. Rostek, W. Pikto-Pietkiewicz, M. Dluzniewski, A. Antoniewicz, S. Poletajew, A. Borowka, T. Pasierski, S. K. Malyutina, M. Ryabikov, J. Ragino, A. Ryabikov, S. Sitia, L. Tomasoni, F. Atzeni, L. Gianturco, P. Sarzi-Puttini, V. De Gennaro Colonna, M. Turiel, F. R. Gutierrez, G. Lefhtheriotis, R. T. Hurst, M. R. Nelson, F. Mookadam, V. Thota, U. Emani, M. Al Harthi, J. Stepanek, S. Cha, S. J. Lester, E. M. M. Ho, L. Hemeryck, M. Hall, K. Scott, K. Bennett, A. Mahmud, C. Daly, G. King, R. T. Murphy, A. S. Brown, A. J. Teske, J. D'Hooge, P. Claus, F. Rademakers, L. Santos, N. Cortez-Dias, S. Goncalves, M. Almeida Ribeiro, A. Bordalo E Sa, C. Magnino, P. Marcos-Alberca, A. Milan, C. Almeria, V. Caniadas, J. L. Rodrigo, L. Perez De Isla, J. L. Zamorano, U. Gustafsson, M. Larsson, P. Lindqvist, L. Brodin, A. Waldenstrom, B. Roosens, S. Hernot, S. Droogmans, G. Van Camp, T. Lahoutte, B. Cosyns, C. M. Rao, D. Aguglia, G. Casciola, C. Imbesi, A. Marvelli, M. Sgro, D. Benedetto, R. Tripepi, C. Zoccali, F. A. Benedetto, L. P. Badano, M. Cardillo, L. Del Mestre, P. Gianfagna, A. Proclemer, H. D. Tschernich, B. Mora, E. Base, U. Weber, J. Dumfarth, C. Mukherjee, H. S. Skaltsiotis, A. K. Kaladaridis, D. B. Bramos, G. K. Kottis, A. A. Antoniou, I. A. Agrios, D. T. Takos, N. V. Vasiladiotis, K. P. Pamboucas, S. T. T. Toumanidis, A. Shim, P. Lipec, B. Michalski, B. Wozniakowski, L. Stefanczyk, A. Rotkiewicz, M. Cameli, M. Lisi, M. Padeletti, E. Bigio, S. Bernazzali, C. Tsoulpas, M. Maccherini, M. Henein, S. Mondillo, I. Garcia Lunar, S. Mingo Santos, V. Monivas Palomero, C. Mitroi, P. Beltran Correas, L. Ruiz Bautista, A. Muniz Lozano, M. Gonzalez Gonzalez, B. Stegemann, K. Willson, R. Zeppellini, A. Iavernaro, M. Zadro, M. Carasi, R. De Domenico, T. Rigo, E. Artuso, G. Erente, A. Ramondo, T. T. Le, F. Q. Huang, Y. Gu, and R. S. Tan
Subjects: Cardiac function curve, medicine.medical_specialty, medicine.anatomical_structure, business.industry, Ventricle, Internal medicine, medicine, Cardiology, Radiology, Nuclear Medicine and imaging, General Medicine, Cardiology and Cardiovascular Medicine, Rotation, business
Published: 2010
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8. Prognostic impact of ventricular indices: Systemic hypertension

Author: W. Zahid, K. Haugaa, D. Bergestuen, H. Skulstad, E. Thiis-Evensen, E. Fosse, T. Edvardsen, C. Magnino, P. Omede', W. Grosso Marra, M. Chiarlo, D. Presutti, C. Bucca, C. Moretti, F. Gaita, F. Veglio, A. Milan, B. Smith, G. Dobson, J. Grapsa, P. Nihoyannopoulos, J. Jaroch, K. Loboz-Grudzien, S. Magda, M. Florescu, Z. Bociaga, A. Ciobanu, E. Kruszynska, K. Dudek, D. Vinereanu, A. Ryabikov, S. Malyutina, S. Shakhmatov, G. Simonova, V. Gafarov, E. Veryovkin, W. Krol, W. Braksator, M. Konopka, M. Kuch, W. Gierlak, H. Krysztofiak, K. Burkhard-Jagodzinska, A. Mamcarz, M. Dluzniewski, B. Ciecierzynska, M. Loboz-Rudnicka, W. Rychard, J. Polanski, S.-O. Granstam, E. Bjorklund, M. Roos, D. Shah, G. Coghlan, E. Papadimitraki, A. Dellaportas, A. Kotrotsou, I. Mourouzis, I. Vlachodimitris, S. Spiropoulos, D. Karagiannakis, G. Anastasiadis, and C. Economou
Subjects: medicine.medical_specialty, business.industry, Internal medicine, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Cardiology and Cardiovascular Medicine, business
Published: 2012
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9. DC conductivity of metal/DLC/Si/metal heterostructures

Author: G. W. Bak, M. Dluzniewski, and E. Staryga
Subjects: Materials science, Diamond-like carbon, Silicon, business.industry, Transistor, chemistry.chemical_element, Heterojunction, Substrate (electronics), Conductivity, law.invention, chemistry, Electrical resistivity and conductivity, law, Electronic engineering, Optoelectronics, Electrical and Electronic Engineering, business, Diode
Abstract: Electrical conduction of metal/DLC/silicon/metal heterostructures has been investigated, Both DLC/p-Si and DLC/n-Si systems shows rectifying properties. The current-voltage (I-V) characteristics of the heterostructures can be described well by the simplified diode equation with the ideality factor between 21.2 and 3.25, decreasing with increasing temperature. The directive tendency of I-V characteristics is independent of the type of silicon substrate. A simple qualitative band model of DLC/Si junction is proposed.
Published: 2001
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10. Application of vibroacoustic method for viscosity measurements in nematic liquid crystals

Author: M. Dominiak, M. Dluzniewski, B. Zoltowski, and Andrzej Lipinski
Subjects: Viscosity, Optics, Materials science, Liquid crystal, business.industry, Optical engineering, Viscometer, Ultrasonic sensor, Composite material, business
Abstract: A computerized measuring setup based on ultrasonic vibratory viscometer is described. Measurements of temperature dependence of the viscosity in nonoriented samples of nematic liquid crystals are presented as examples of application of the equipment.© (1993) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Published: 1993
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11. P238 Efficacité et tolérance de l’association fénofibrate 160 mg/pravastatine 40 mg chez des patients diabétiques de type 2 en prévention primaire et avec hypercholestérolémie mixte

Author: K. Retterstol, M. Farnier, A. Csazar, A. Steinmetz, and M. Dluzniewski
Subjects: Endocrinology, Endocrinology, Diabetes and Metabolism, Internal Medicine, General Medicine
Abstract: Introduction Pour atteindre les objectifs recommandes sur les taux de LDL-cholesterol (LDL-C) et non HDL-cholesterol (non HDL-C) dans le diabete de type 2, il est souvent necessaire d’avoir recours a une association therapeutique. L’objectif de cette etude a ete d’evaluer l’efficacite et la tolerance d’une association fixe fenofibrate 160 mg/pravastatine 40 mg chez des patients avec diabete de type 2 sans antecedent cardiovasculaire et non aux objectifs sous simvastatine 20 mg. Patients et Methodes Il s’agit d’une etude multicentrique, randomisee, en double aveugle et groupes paralleles realisee dans 73 centres europeens. Apres une phase preliminaire de 6 semaines de stabilisation sous simvastatine 20 mg, 291 patients avec non HDL-C ≥ 1,30 g/l ou LDL-C ≥ 1,00 g/l et triglycerides (TG) ≥ 1,50 g/l et ≤ 6,00 g/l ont ete randomises pour recevoir pendant 12 semaines soit l’association fenofibrate 160 mg/pravastatine 40 mg, soit la simvastatine 20 mg. Le critere principal d’efficacite etait le pourcentage moyen de variation du non HDL-C et les criteres secondaires incluaient les evolutions des taux de HDL-C, TG, LDL-C, apoB et fibrinogene. Resultats Au terme des 12 semaines de traitement, le non HDL-C a ete plus reduit sous fenofibrate 160 mg/pravastatine 40 mg que sous simvastatine 20 mg (-12,9 % vs -6,8 %, p = 0,008). L’association fenofibrate 160 mg/pravastatine 40 mg a egalement ete plus efficace pour reduire le taux de TG (-28,6% vs 5,0 %, p Conclusion L’association fenofibrate 160 mg/pravastatine 40 mg est plus efficace que la simvastatine 20 mg pour ameliorer le profil lipidique de patients diabetiques de type 2 avec hypercholesterolemie mixte en prevention primaire.
Published: 2010
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12. Th-P15:181 Implications of low HDL-C and high homocysteine levels for left ventricular akinesis in patients with acute coronary syndrome

Author: W. Braksator, E. Burbicka, M. Dluzniewski, E. Kostarska-Srokosz, H. Bukowska, Kornel Chełstowski, and Naruszewicz Marek
Subjects: medicine.medical_specialty, Acute coronary syndrome, business.industry, Internal medicine, Internal Medicine, Cardiology, Medicine, In patient, General Medicine, Homocysteine levels, Cardiology and Cardiovascular Medicine, business, medicine.disease
Published: 2006
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13. Tu-P7:108 The systolic and diastolic function of the left ventricle in the patients WTH diabetes mellitus or metabolic syndrome

Author: A. Mamcarz, W. Braksator, Maciej Janiszewski, A. Cudnoch-Jedrzejewska, and M. Dluzniewski
Subjects: medicine.medical_specialty, E/A ratio, business.industry, General Medicine, medicine.disease, medicine.anatomical_structure, Ventricle, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Cardiology, Diastolic function, Metabolic syndrome, Cardiology and Cardiovascular Medicine, business
Published: 2006
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14. Tu-W27:7 Combination therapy of statin with flavonoids-rich extract from chokeberry fruits enhanced reduction in CAD risk markers in patients after MI

Author: B. Milo, M. Naruszewicz, M. Dluzniewski, and I. Laniewska
Subjects: medicine.medical_specialty, Statin, Combination therapy, business.industry, medicine.drug_class, CAD, General Medicine, Pharmacology, Gastroenterology, Reduction (complexity), Internal medicine, Internal Medicine, medicine, In patient, Cardiology and Cardiovascular Medicine, business
Published: 2006
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15. A12-6 Which factors determinate the efficacy of low energy transesophageal cardioversion of paroxysmal atrial fibrillation

Author: W. Braksator, M. Moszczenski, M. Dluzniewski, J. Krol, M. Tomaszewska-Kiecana, and W. Mojkowski
Subjects: medicine.medical_specialty, Low energy, business.industry, Paroxysmal atrial fibrillation, Physiology (medical), Internal medicine, medicine.medical_treatment, medicine, Cardiology, Electric countershock, Cardiology and Cardiovascular Medicine, Cardioversion, business
Published: 2003
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16. [Effect of polarizing mixture (potassium, insulin, glucose) on the concentration of free fatty acids in acute myocardial infarct]

Author: T, Zaleska, M, Dluzniewski, and L, Ceremuzynnski
Subjects: Adult, Glucose, Acute Disease, Myocardial Infarction, Potassium, Humans, Insulin, Fatty Acids, Nonesterified, Middle Aged, Aged
Published: 1977

17. Suppression of catecholamine excretion by low doses of clonidine in healthy subjects and feasibility study on clonidine application in angina pectoris

Author: L, Ceremuzyński, W, Lada, J, Maruchin, M, Dluzniewski, and K, Herbacyńska-Cedro
Subjects: Adult, Male, Catecholamines, Double-Blind Method, Heart Rate, Humans, Blood Pressure, Female, Middle Aged, Clonidine, Aged, Angina Pectoris
Abstract: The effect of low doses of clonidine (CL) (150 microgram/day p.o.) on catecholamine (CA) excretion, blood pressure (BP) and heart rate (HR) was investigated in a double-blind way on 9 healthy volunteers. CL administration for two consecutive days led to marked diminution of urinary CA, mainly of epinephrine, with only slight decrease in systolic BP and HR. The results show that this dose of CL is effective in suppressing adrenergic tone as reflected by the magnitude of CA excretion, without marked influence upon systemic BP. Subsequently, the same dose of the drug was administered for two weeks to 30 unselected patients with intractable angina known to be often associated with adrenergic overactivity. Clinical improvement manifested by complete disappearance of coronary pains or marked decrease in the incidence of anginal attacks was achieved in the majority (over 60%) of patients. Although best results were seen in patients with borderline hypertension, the drug was also effective in normotensive patients and no untoward hypotensive symptoms were noted throughout the trial. Blood CA and free fatty acids (FFA) measurements performed in 5 patients showed that favourable clinical effect of CL therapy coincides with lowering of CA and FFA levels. This study indicates that CL administered in a dose which does suppress adrenergic activity might be of value in the treatment of coronary patients. Favourable results of this preliminary trial incline to undertake well controlled clinical study.
Published: 1979

18. History of Lyme Disease as a Predictor of Atrial Fibrillation.

Author: Szymanska A, Platek AE, Dluzniewski M, and Szymanski FM
Subjects: Aged, Aged, 80 and over, Antibodies, Bacterial immunology, Borrelia burgdorferi Group immunology, Echocardiography, Female, Humans, Immunoglobulin G immunology, Lyme Disease immunology, Male, Multivariate Analysis, Risk Factors, Serologic Tests, Atrial Fibrillation epidemiology, Lyme Disease epidemiology
Abstract: In many cases, atrial fibrillation (AF) is associated with a history of cardiac inflammation. One of the potential pathogens responsible for atrial inflammation might be Borrelia burgdorferi - a pathogen involved in Lyme carditis. This study aimed to assess whether the serological history of Borrelia infection was associated with the risk of AF. The study included 113 AF patients and 109 patients in sinus rhythm. All patients underwent a clinical evaluation, echocardiography and had their blood taken for the assessment of anti-Borrelia IgG antibodies. Patients with AF compared with the non-AF group had more often serological signs of Borrelia infection (34.5% vs 6.4%; p <0.0001). The multivariate analysis showed that positive results for anti-Borrelia IgG antibodies were a strong independent predictor of AF (odds ratio 8.21; 95% confidence interval 3.08 to 21.88; p < 0.0001). In conclusion, presented data show that exposure to Borrelia spp. infection is associated with an increased risk of AF. Whether the early treatment of Lyme disease lowers the risk of AF development remains to be explored., (Copyright © 2020 Elsevier Inc. All rights reserved.)
Published: 2020
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19. Acute limb ischemia due to intracardiac myxoma in a patient with atrial fibrillation.

Author: Szymanska A, Syska-Suminska J, Rekosz J, Skrobisz A, Platek AE, and Dluzniewski M
Subjects: Acute Disease, Aged, 80 and over, Arterial Occlusive Diseases diagnostic imaging, Arterial Occlusive Diseases pathology, Arterial Occlusive Diseases therapy, Atrial Fibrillation diagnosis, Atrial Fibrillation physiopathology, Endovascular Procedures, Female, Heart Atria pathology, Heart Neoplasms diagnostic imaging, Heart Neoplasms pathology, Humans, Ischemia diagnostic imaging, Ischemia physiopathology, Ischemia therapy, Myxoma diagnostic imaging, Myxoma pathology, Treatment Outcome, Arterial Occlusive Diseases etiology, Atrial Fibrillation complications, Heart Neoplasms complications, Ischemia etiology, Lower Extremity blood supply, Myxoma complications, Neoplastic Cells, Circulating pathology
Published: 2019
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20. Circulating miR-30a-5p as a prognostic biomarker of left ventricular dysfunction after acute myocardial infarction.

Author: Maciejak A, Kostarska-Srokosz E, Gierlak W, Dluzniewski M, Kuch M, Marchel M, Opolski G, Kiliszek M, Matlak K, Dobrzycki S, Lukasik A, Segiet A, Sygitowicz G, Sitkiewicz D, Gora M, and Burzynska B
Subjects: Acute Disease, Aged, Biomarkers blood, Female, Gene Expression Regulation, Heart Failure complications, Humans, Male, MicroRNAs genetics, Middle Aged, Myocardial Infarction complications, Myocardial Infarction physiopathology, Prognosis, MicroRNAs blood, Myocardial Infarction blood, Myocardial Infarction diagnosis, Ventricular Dysfunction, Left complications
Abstract: Left ventricular (LV) dysfunction after acute myocardial infarction (AMI) is associated with an increased risk of heart failure (HF) development. Diverse microRNAs (miRNAs) have been shown to appear in the bloodstream following various cardiovascular events. The aim of this study was to identify prognostic miRNAs associated with LV dysfunction following AMI. Patients were divided into subgroups comprising patients who developed or not LV dysfunction within six months of the infarction. miRNA profiles were determined in plasma and serum samples of the patients on the first day of AMI. Levels of 14 plasma miRNAs and 16 serum miRNAs were significantly different in samples from AMI patients who later developed LV dysfunction compared to those who did not. Two miRNAs were up-regulated in both types of material. Validation in an independent group of patients, using droplet digital PCR (ddPCR) confirmed that miR-30a-5p was significantly elevated on admission in those patients who developed LV dysfunction and HF symptoms six months after AMI. A bioinformatics analysis indicated that miR-30a-5p may regulate genes involved in cardiovascular pathogenesis. This study demonstrates, for the first time, a prognostic value of circulating miR-30a-5p and its association with LV dysfunction and symptoms of HF after AMI.
Published: 2018
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21. Echocardiographic assessment of right ventricle adaptation to endurance training in young rowers - speckle tracking echocardiography.

Author: Konopka M, Krol W, Burkhard-Jagodzinska K, Jakubiak A, Klusiewicz A, Chwalbinska J, Pokrywka A, Sitkowski D, Dluzniewski M, and Braksator W
Abstract: The aim of this study was to determine the relationship between the degree of cardiorespiratory fitness and the function of the right ventricle (RV). 117 rowers, age 17.5±1.5 years. All subjects underwent cardiopulmonary exercise. Standard echocardiography and 2D speckle tracking echocardiography with evaluation of longitudinal strain in each segment of the RV (basal - RVLS-B; mid - RVLS-M, apical - RVLS-A) and global RV free-wall strain (RVLS-G) were performed. RVLS-B values were lower compared to the RVLS-M (-25.8±4.4 vs -29.3±3.5; p<0.001) and RVLS-A values (-25.8±4.4 vs -26.2±3.4; p=0.85). Correlations between VO 2 max and RVLS were observed in men: RVLS-G strain (r = 0.43; p <0.001); RVLS-B (r = 0.30; p = 0.02); RVLS-M (r = 0.38; p = 0.02). A similar relationship was not observed in the group of women. The strongest predictors corresponding to a change in global and basal strain were VO 2 max and training time: RVLS-G (VO 2 max: β = 0.18, p = 0.003; training time: β = -0.39; p = 0.02) and RVLS-B (VO 2 max: β = 0.23; p = 0.0001 training time: β = -1.16; p = 0.0001). The global and regional reduction of RV systolic function positively correlates with the level of fitness, and this relationship is observed already in young athletes. The character of the relationship between RV deformation parameters and the variables that determine the physical performance depend on gender. The dependencies apply to the proximal fragment of the RV inflow tract, which may be a response to the type of flow during exercise in endurance athletes., Competing Interests: Conflict of interests The authors declared no conflict of interests regarding the publication of this manuscript.
Published: 2016
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22. Association of the CHADS2 and CHA 2DS 2-VASc scores with left atrial enlargement: a prospective cohort study of unselected atrial fibrillation patients.

Author: Hrynkiewicz-Szymanska A, Dluzniewski M, Platek AE, Szymanski FM, Syska-Suminska J, Klos-Szadryn A, Glinka M, Strojek M, Kuciej A, and Tomaszewska-Kiecana M
Subjects: Aged, Aged, 80 and over, Female, Heart Atria physiopathology, Humans, Male, Middle Aged, Risk Factors, Atrial Fibrillation complications, Atrial Fibrillation physiopathology, Electrocardiography, Thromboembolism etiology, Thromboembolism physiopathology
Abstract: Assessment of thromboembolic risk is crucial for proper management of atrial fibrillation (AF) patients. Currently used risk score base only on scarce clinical data and do not take into consideration parameters including echocardiographic findings. The aim of this study was to evaluate if left atrium (LA) enlargement is associated with higher thromboembolic risk assessed by CHADS2 and CHA2DS2-VASc scores in a cohort of unselected non-valvular AF patients. Data from 582 AF hospitalizations occurring between November 2012 and January 2014 were analyzed. All patients underwent a standard transthoracic echocardiography and had their thromboembolic risk assessed in both CHADS2 and CHA2DS2-VASc scores. In 494 enrolled patients (48.5 % male; mean age 73.4 ± 11.5 years) AF was classified as paroxysmal in 233 (47.3 %), as persistent in 109 (22.1 %), and as permanent in 151 (30.6 %) patients. LA was enlarged in 426 (86.2 %) patients. Enlargement was classified as mild in 99 (20.0 %) patients, as moderate in 130 (26.3 %) patients, and as severe in 196 (39.7 %) patients. Patients with enlarged LA had higher mean CHADS2 score (2.0 ± 1.5 vs. 2.6 ± 1.3; p = 0.0005) and CHA2DS2-VASc (3.8 ± 2.0 vs. 4.4 ± 1.8; p = 0.02) score than patients with normal LA. The both mean scores rose along with rising LA diameter. LA enlargement is highly prevalent in AF patients. Higher thromboembolic risk assessed by both CHADS2 and CHA2DS2-VASc scores is associated with presence of LA enlargement. Echocardiographically assessed LA size may be an additional parameter useful in thromboembolic risk stratification of AF patients.
Published: 2015
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23. The influence of extreme mixed exertion load on the right ventricular dimensions and function in elite athletes: a tissue Doppler study.

Author: Krol W, Braksator W, Kasprzak JD, Kuch M, Mamcarz A, Chybowska B, Krysztofiak H, and Dluzniewski M
Subjects: Adult, Analysis of Variance, Case-Control Studies, Female, Humans, Male, Athletes, Echocardiography, Doppler methods, Heart Ventricles diagnostic imaging, Physical Exertion physiology, Ventricular Function, Right physiology
Abstract: Aims: The athlete's heart is a widely discussed topic regarding the adaptation of the left ventricle (LV) to regular training. The data on the morphology and-even more-the function of the right ventricle (RV) are less well studied. The aim of the study was to assess the influence of prolonged exertion on morphology and function of the RV., Methods and Results: We examined 38 elite athletes, members of the Polish Olympic Team and a control group of 41 age and sex-matched healthy volunteers. Specifically, we assessed the details of RV size and function including: RV enlargement, transtricuspid systolic gradient, and dilatation of main pulmonary artery (PA) as compared with the values derived from the control group. There was no significant difference in the function of the RV assessed using tissue Doppler echocardiography (TDE) between the athletes and controls (S': 15.0 cm/sec vs. 14.0 cm/sec; E': 15.8 cm/sec vs. 15.7 cm/sec; A': 9.9 cm/sec vs. 10.4 cm/sec), but the athletes had a higher transtricuspid systolic gradient (23.6 mm Hg vs. 19.0 mm Hg, P = 0.004). There were no significant differences in TDE velocities in athletes with dilated RV or PA. However, those with elevated tricuspid regurgitation velocity had lower systolic velocities of the tricuspid annulus then the rest (S': 12.3 cm/sec vs. 15.5 cm/sec, P = 0.01)., Conclusions: RV enlargement in professional athletes is not connected with deterioration of diastolic or systolic RV function. Athletes with elevated pulmonary systolic pressure at rest, however, present with lower longitudinal systolic velocities of RV assessed using TDE., (© 2011, Wiley Periodicals, Inc.)
Published: 2011
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24. [Noninvasive characterization of a case of Danon disease].

Author: Braksator W, Chybowska B, Kuch M, and Dluzniewski M
Subjects: Humans, Male, Young Adult, Glycogen Storage Disease Type IIb diagnosis
Published: 2010

25. Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.

Author: Patten M, Maas R, Bauer P, Lüderitz B, Sonntag F, Dluzniewski M, Hatala R, Opolski G, Müller HW, and Meinertz T
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Drug Therapy, Combination, Electrocardiography, Humans, Male, Middle Aged, Prospective Studies, Survival Analysis, Treatment Outcome, Anti-Arrhythmia Agents administration & dosage, Quinidine administration & dosage, Sotalol administration & dosage, Tachycardia drug therapy, Verapamil administration & dosage
Abstract: Aim: The indication to treat paroxysmal atrial fibrillation (PAF) is controversial. The Suppression of Paroxysmal Atrial Tachyarrhythmias (SOPAT) trial was designed to answer the following questions: (1) What is the average rate of spontaneous events of symptomatic PAF with and without anti-arrhythmic medication? (2) what is the prevalence of severe side-effects? and (3) is the fixed combination of Quinidine + Verapamil inferior to the efficacy of sotalol or not?, Methods and Results: Within 60 months 172 centres in Germany, Poland, and The Slovak Republic prospectively enrolled 1033 patients (mean age 60 years, 62% male) with documented frequent episodes of symptomatic PAF. Patients were randomised to either Quinidine + Verapamil 480/240 mg/d (high dose; 263 patients), Quinidine + Verapamil 320/160 mg/d (low dose; 255 patients), Sotalol 320 mg/d (264 patients) or placebo (251 patients), of which 1012 patients entered the intention-to-treat analysis. The primary endpoint was the time to first recurrence of symptomatic PAF or premature discontinuation. Secondary outcome parameters were the total number of symptomatic episodes and tolerability of the tested drugs. Patients were followed for a period of up to 12 months by daily and symptom-triggered trans-telephonic ECG-monitoring (Tele-ECG). The mean time under treatment was 233 +/- 152 days. Regarding the primary endpoint, all active treatments were superior to placebo and not different from each other. A total of 756 patients reached the primary endpoint within 105.7 +/- 8.7 d (mean +/- SEM) in the placebo group, vs. Quinidine + Verapamil (high dose) (150.4 +/- 10 d, p = 0.0061), vs. Quinidine + Verapamil (low dose) (148.9 +/- 10.6 d, p = 0.0006), vs. Sotalol (145.6 +/- 93 d, p = 0.0007). All three treatments were also effective in the reduction of AF burden (days with symptomatic AF [%] mean +/- SD, p vs. placebo): Quinidine + Verapamil (high dose) (3.4 +/- 12, p = 0.0001), Quinidine + Verapamil (low dose) (4.5 +/- 12.3, p = 0.008) and Sotalol (2.9 +/- 6.5, p = 0.026) compared to placebo (6.1 +/- 13.5). A total of four deaths, 13 syncopes, and one ventricular tachycardia (VT) occurred during the active study period, of which one death and one VT were related to Quinidine/Verapamil., Conclusion: Taken together, anti-arrhythmic therapy with the fixed combination of Quinidine + Verapamil is as effective as Sotalol in the reduction of the recurrence rate of symptomatic PAF with a low but definite risk of severe side-effects.
Published: 2004
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26. Increase of R-wave in pre-discharge ergometric test after myocardial infarction indicates advanced left ventricular injury, latent serious arrhythmias and worse prognosis.

Author: Bednarz B, Chamiec T, Budaj A, Dluzniewski M, and Ceremuzyński L
Subjects: Adult, Aged, Echocardiography, Follow-Up Studies, Heart Ventricles pathology, Humans, Male, Middle Aged, Prognosis, Arrhythmias, Cardiac diagnosis, Electrocardiography, Exercise Test, Myocardial Infarction mortality, Ventricular Function, Left physiology
Abstract: Changes in R-wave amplitude during exercise tests performed soon after myocardial infarction (15-31 days, mean 22) were analyzed in 78 men in relation to left ventricular injury (determined by 2-D echocardiography), ventricular arrhythmias (24-h Holter monitoring) and survival after myocardial infarction. It has been found that in patients with mild left ventricular injury (n = 51, Heger index < or = 3) the sum of the R-wave amplitude in 15 precordial leads recorded immediately after exercise decreased by 3.7 +/- 10% in comparison with resting values. In the patients with major left ventricular injury (n = 26, Heger Index > 3) the sum of R-wave amplitude after exercise increased by 12.9 +/- 17.5% (P < 0.001). Positive linear correlation (r = 0.35, P < 0.01) was observed between the level of left ventricular wall motion disturbances and R-wave amplitude changes. In patients with normal or slightly disturbed cardiac rhythm (n = 42, Lown scale 0-2) the sum of the R-wave amplitude after exercise decreased by 5 +/- 18% as compared to resting values, whereas in the patients with complex arrhythmias (n = 23, Lown scale 3-5) the sum of R-wave amplitude increased amounting to 9.9 +/- 17% (P < 0.001). Out of 17 patients who died during 5-year follow up, 16 displayed an increase or no change of the sum of R-wave amplitude. The same kind of relations between R-wave amplitude changes and left ventricular injury or cardiac arrhythmias were noted in patients with anterior and inferior myocardial infarction.(ABSTRACT TRUNCATED AT 250 WORDS)
Published: 1993
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27. The value of transesophageal atrial pacing in predicting the efficacy of antiarrhythmic drugs in patients with paroxysmal narrow QRS complex tachycardia.

Author: Kulakowski P, Dluzniewski M, O'Nunain S, Camm AJ, Wardzynska M, and Ceremuzynski L
Subjects: Adult, Evaluation Studies as Topic, Female, Humans, Male, Predictive Value of Tests, Recurrence, Sensitivity and Specificity, Tachycardia, Paroxysmal drug therapy, Tachycardia, Paroxysmal epidemiology, Tachycardia, Supraventricular drug therapy, Tachycardia, Supraventricular epidemiology, Anti-Arrhythmia Agents therapeutic use, Cardiac Pacing, Artificial methods, Electrocardiography, Tachycardia, Paroxysmal diagnosis, Tachycardia, Supraventricular diagnosis
Abstract: Transesophageal atrial pacing (TAP) is used in the diagnosis and treatment of paroxysmal narrow QRS complex tachycardia (NQT). The aim of this study was to assess the value of this technique in predicting the efficacy of antiarrhythmic therapy. The study group consisted of 30 consecutive patients with spontaneous NQT whose clinical tachycardia was inducible by TAP. Baseline TAP was performed off all antiarrhythmic medication and repeated during oral antiarrhythmic drug therapy. The pacing protocol consisted of three stages: a single extrastimulus introduced at progressively shorter coupling intervals during sinus rhythm, pacing at incremental rates to the point of second-degree AV block, and bursts of rapid pacing. On repeat stimulation while on oral antiarrhythmic therapy (37 pacing studies) NQT was still inducible in 12 cases. During the follow-up period ten patients developed a recurrence of NQT:nine cases out of 12 (75%), in whom NQT was inducible while on antiarrhythmic therapy, and one case out of 25 (4%), in whom NQT was not inducible (P less than 0.001). The sensitivity of TAP in predicting the outcome of the patients with NQT was 90%, and the specificity 89%. The negative predictive value of TAP (prediction of no recurrence of NQT) was 96%, and the positive predictive value (prediction of recurrence of NQT) was 75%. We conclude that TAP is a simple and accurate method for predicting the efficacy of antiarrhythmic treatment in patients with NQT.
Published: 1992
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28. Relationship between signal-averaged electrocardiography and dangerous ventricular arrhythmias in patients with left ventricular aneurysm after myocardial infarction.

Author: Kulakowski P, Dluzniewski M, Budaj A, and Ceremuzynski L
Subjects: Adult, Aged, Aged, 80 and over, Arrhythmias, Cardiac complications, Arrhythmias, Cardiac etiology, Death, Sudden, Cardiac etiology, Echocardiography, Electrocardiography, Ambulatory, Female, Follow-Up Studies, Heart Aneurysm diagnostic imaging, Heart Aneurysm etiology, Heart Ventricles, Humans, Logistic Models, Male, Middle Aged, Predictive Value of Tests, Prognosis, Sensitivity and Specificity, Signal Processing, Computer-Assisted, Tachycardia complications, Tachycardia diagnosis, Tachycardia etiology, Arrhythmias, Cardiac diagnosis, Electrocardiography instrumentation, Heart Aneurysm complications, Myocardial Infarction complications
Abstract: We performed signal-averaged electrocardiography (SAECG) and Holter monitoring, and subsequently followed-up 53 ambulatory patients with left ventricular aneurysm (LVA) after myocardial infarction (MI). A history of spontaneous episodes of sustained ventricular tachycardia (VT) was also analysed. Out of 53 patients, 25 (47%) had an abnormal SAECG. Abnormal SAECG correctly identified nine out of 10 cases with a history of sustained VT. Complex ventricular arrhythmias were detected on Holter monitoring in 23 patients: in five out of 28 with normal SAECG (18%) and in 18 out of 25 with abnormal SAECG (72%) (P less than 0.001). During follow-up (mean 19 months) sustained VT and/or sudden cardiac death (SCD) occurred in eight cases, out of which seven had an abnormal SAECG. The negative predictive value of SAECG (no VT or SCD during follow-up) was very high, 96%, similar to the negative predictive value of a history of sustained VT (93%). Using multivariate analysis only a history of sustained VT was an independent factor in predicting the outcome of patients in this study. We conclude that an abnormal SAECG identifies those post infarction patients with LVA who are prone to complex ventricular arrhythmias. A normal SAECG and an absence of a history of sustained VT strongly indicate that the risk of developing arrhythmic events is very low.
Published: 1991
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29. [Effect of polarizing mixture (potassium, insulin, glucose) on the concentration of free fatty acids in acute myocardial infarct].

Author: Zaleska T, Dluzniewski M, and Ceremuzynnski L
Subjects: Acute Disease, Adult, Aged, Humans, Middle Aged, Fatty Acids, Nonesterified blood, Glucose pharmacology, Insulin pharmacology, Myocardial Infarction blood, Potassium pharmacology
Published: 1977

30. Suppression of catecholamine excretion by low doses of clonidine in healthy subjects and feasibility study on clonidine application in angina pectoris.

Author: Ceremuzyński L, Lada W, Maruchin J, Dluzniewski M, and Herbacyńska-Cedro K
Subjects: Adult, Aged, Angina Pectoris blood, Angina Pectoris physiopathology, Blood Pressure drug effects, Catecholamines blood, Clonidine therapeutic use, Double-Blind Method, Female, Heart Rate drug effects, Humans, Male, Middle Aged, Angina Pectoris drug therapy, Catecholamines urine, Clonidine pharmacology
Abstract: The effect of low doses of clonidine (CL) (150 microgram/day p.o.) on catecholamine (CA) excretion, blood pressure (BP) and heart rate (HR) was investigated in a double-blind way on 9 healthy volunteers. CL administration for two consecutive days led to marked diminution of urinary CA, mainly of epinephrine, with only slight decrease in systolic BP and HR. The results show that this dose of CL is effective in suppressing adrenergic tone as reflected by the magnitude of CA excretion, without marked influence upon systemic BP. Subsequently, the same dose of the drug was administered for two weeks to 30 unselected patients with intractable angina known to be often associated with adrenergic overactivity. Clinical improvement manifested by complete disappearance of coronary pains or marked decrease in the incidence of anginal attacks was achieved in the majority (over 60%) of patients. Although best results were seen in patients with borderline hypertension, the drug was also effective in normotensive patients and no untoward hypotensive symptoms were noted throughout the trial. Blood CA and free fatty acids (FFA) measurements performed in 5 patients showed that favourable clinical effect of CL therapy coincides with lowering of CA and FFA levels. This study indicates that CL administered in a dose which does suppress adrenergic activity might be of value in the treatment of coronary patients. Favourable results of this preliminary trial incline to undertake well controlled clinical study.
Published: 1979

31. ST 567 compared with propranolol in stable angina.

Author: Ceremuzynski L, Nartowicz E, Dluzniewski M, Perkowicz J, Czarnecki W, Burduk P, Budaj A, Bednarz B, Chamiec T, and Jurgiel R
Subjects: Blood Pressure drug effects, Clinical Trials as Topic, Clonidine therapeutic use, Double-Blind Method, Exercise Test, Humans, Male, Middle Aged, Random Allocation, Angina Pectoris drug therapy, Anti-Arrhythmia Agents therapeutic use, Clonidine analogs & derivatives, Heart Rate drug effects, Propranolol therapeutic use
Abstract: Unlabelled: The aim of this study was to investigate the effectiveness of ST 567 in patients suffering from ischaemic heart disease and to compare the effects of this drug with those of propranolol. The study group consisted of 48 male patients, mean age 53, with stable, exercise-induced angina pectoris. After a two-week run-in-placebo period, the patients were randomized to treatment with ST 567 3 X 30 mg (N = 24) and propranolol, 3 X 40 mg (N = 24). The drugs were administered in a double blind fashion during four weeks. Heart rate at rest was decreased by ST 567 from 76 to 65 (P less than 0.005) by propranolol from 76 to 62 (P less than 0.001). Systolic blood pressure was lowered by ST 567 from 131 to 121 (NS) and by propranolol from 133 to 118 (P less than 0.05). Exercise tolerance was increased by ST 567 from 20 X 10(3) to 34 X 10(3) J (P less than 0.05), by propranolol from 26 X 10(3) to 32 X 10(3) J (P less than 0.01) (mean values). Anginal attacks (no. per week) were reduced by ST 567 from 14 to 7 (P less than 0.05) and by propranolol from 14 to 5 (P less than 0.01). Nitroglycerin consumption in no. of tablets per week decreased in ST 567 from 12 to 7 (P less than 0.01), in propranolol from 11 to 4 (P less than 0.0). There were 7 drop outs during treatment with ST 567:2 cases of myocardial infarction, exacerbation of angina in 2 patients, visual disturbances in 2 patients, vertigo in 1 patient. With propranolol we observed worsening of angina in 1 patient, with disturbances in sexual potency in 1., In Conclusion: ST 567 is an effective agent in chronic angina but slightly less effective than propranolol in the dosages studied.
Published: 1987
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31 results on '"M. Dluzniewski"'

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11. P238 Efficacité et tolérance de l’association fénofibrate 160 mg/pravastatine 40 mg chez des patients diabétiques de type 2 en prévention primaire et avec hypercholestérolémie mixte

12. Th-P15:181 Implications of low HDL-C and high homocysteine levels for left ventricular akinesis in patients with acute coronary syndrome

13. Tu-P7:108 The systolic and diastolic function of the left ventricle in the patients WTH diabetes mellitus or metabolic syndrome

14. Tu-W27:7 Combination therapy of statin with flavonoids-rich extract from chokeberry fruits enhanced reduction in CAD risk markers in patients after MI

15. A12-6 Which factors determinate the efficacy of low energy transesophageal cardioversion of paroxysmal atrial fibrillation

16. [Effect of polarizing mixture (potassium, insulin, glucose) on the concentration of free fatty acids in acute myocardial infarct]

17. Suppression of catecholamine excretion by low doses of clonidine in healthy subjects and feasibility study on clonidine application in angina pectoris

18. History of Lyme Disease as a Predictor of Atrial Fibrillation.

19. Acute limb ischemia due to intracardiac myxoma in a patient with atrial fibrillation.

20. Circulating miR-30a-5p as a prognostic biomarker of left ventricular dysfunction after acute myocardial infarction.

21. Echocardiographic assessment of right ventricle adaptation to endurance training in young rowers - speckle tracking echocardiography.

22. Association of the CHADS2 and CHA 2DS 2-VASc scores with left atrial enlargement: a prospective cohort study of unselected atrial fibrillation patients.

23. The influence of extreme mixed exertion load on the right ventricular dimensions and function in elite athletes: a tissue Doppler study.

24. [Noninvasive characterization of a case of Danon disease].

25. Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.

26. Increase of R-wave in pre-discharge ergometric test after myocardial infarction indicates advanced left ventricular injury, latent serious arrhythmias and worse prognosis.

27. The value of transesophageal atrial pacing in predicting the efficacy of antiarrhythmic drugs in patients with paroxysmal narrow QRS complex tachycardia.

28. Relationship between signal-averaged electrocardiography and dangerous ventricular arrhythmias in patients with left ventricular aneurysm after myocardial infarction.

29. [Effect of polarizing mixture (potassium, insulin, glucose) on the concentration of free fatty acids in acute myocardial infarct].

30. Suppression of catecholamine excretion by low doses of clonidine in healthy subjects and feasibility study on clonidine application in angina pectoris.

31. ST 567 compared with propranolol in stable angina.

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