5 results on '"M. Bulent Ozdemir"'
Number of results to display per page
Search Results
2. THE IMMUNOHISTOCHEMICAL, MORPHOMETRIC AND BIOCHEMICAL EVALUATION OF SYSTEMICALLY ADMINISTERED BORIC ACID ON LIPOPOLYSACCHARIDE-INDUCED PERIODONTITIS IN DIABETIC RATS
- Author
-
Havva Muge Balseven, Gulcin Mete, Nazli Cil, M. Bulent Ozdemir, Ergun Mete, Yasar Enli, Barbaros Sahin, Hande Senol, Sivge Kurgan, Meral Gunhan, Canan Onder, Havva Muge Balseven, Gulcin Mete, Nazli Cil, M. Bulent Ozdemir, Ergun Mete, Yasar Enli, Barbaros Sahin, Hande Senol, Sivge Kurgan, Meral Gunhan, and Canan Onder
- Abstract
Background: The aim of this study was to evaluate the effects of systemically administred boric acid (BA) on lipopolysaccharide-induced periodontitis, histopathological changes and antioxidant status in diabetic rats. Materials and Methods: 48 Wistar rats were divided into six experimental groups: 1) Control (C, n=8) 2) Lipopolysaccharide only group (LPS, n=8) 3) Streptozotocin only group (STZ, n=8) 4) STZ+LPS group (n=8) 5) STZ+LPS+20 mg/kg/day BA group (BA20, n=8) 6) STZ+LPS+30 mg/kg/day BAgroup (BA30, n=8). Diabetes mellitus was induced by a single injection of 55 mg/kg STZ. Experimental periodontitis was established by applied Escherichia coli (E. Coli) LPS injection into the palatal gingiva between the right maxillary first and second molars for 3 times every 48 hours. BA was given for 10 days. Animals were sacrificed on the 20th day. Alveolar bone loss was evaluated by morphometric analysis. Interleukin (IL)-1β, IL-6, and tumor necrosis factor-α (TNF-α) were evaluated immunohistochemically and serum malondialdehyde (MDA), glutathione (GSH) and superoxide dismutase (SOD) levels were evaluated by biochemical analysis. Results: The highest alveolar bone loss value was observed in the STZ+LPS group. BA groups showed significantly lower bone loss compared to STZ, and STZ+LPS groups (p<0,05). The inflammatory cell counts were found out to be significantly reduced in both BA groups, in comparison to the LPS, STZ, STZ+LPS groups (p<0,05). The osteoblast counts were found out to be significantly increased in both BA groups in comparison to LPS group (p<0,05). And it was found significantly higher in BA30 group compared to STZ group (p<0,05). The osteoclast counts of both BA groups were found out to be significantly decreased compared to STZ and STZ+LPS groups (p<0,05). IL-1, IL-6, and TNF-α levels were found out to be decreased in both BA groups compared to LPS and STZ+LPS groups (p<0,05). MDA levels in BA30 group were lower compared to the STZ+LPS group. SOD and G
- Published
- 2018
3. Platform presentations
- Author
-
Jaime Pereda, Gen Niimi, Jagat Mohini Kaul, Sabita Mishra, Babita Pangtey, Daniele Peri, Vincenza Cannella, Giovanni Peri, A. Valentino, Francesco Li Volsi, Rosaria Lo Verde, E. Russo, A. Sciuto, Annalisa Sunseri, Giuseppe Modica, Gianpiero Gravante, Seok Ling Ong, Matthew Metcalfe, David Lloyd, Ashley Dennison, Veronica Macchi, Andrea Porzionato, Anna Parenti, Raffaele De Caro, Kawthar I. F. Al-Harmni, Zohair I. F. Rahemo, Hussain I. A. Al-Khan, Vedat Bakan, Gulen Demirpolat, Mahmut Bozkurt, Yakup Gumusalan, Niyazi Acer, Mehmet Demir, Hulusi Taskoparan, Akcan Akkaya, Birdal Yildirim, Mehmet Camurdanoglu, Gul Guven, Hilmi Ozden, Sahin Kabay, Cengiz Ustuner, Dilek Burukoglu, Derya Ustuner, Irfan Degirmenci, Fahrettin Akyuz, Neslihan Tekin, Fulya Kucuk, Firdevs Gurer, M. Cengiz Ustuner, Davut Ozbag, Mesut Ozkaya, Harun Ciralik, Fatma Inanc Tolun, Fatih Yuzbasioglu, Seda Arslan, Ghazaleh Moshkdanian, Fatemeh Pouya, Amirmahdi Nematollahi-Mahani, Seyed Noureddin Nematollahi-Mahani, Ralph Ger, Jeremy Nikfarjam, Kathy Dooley, Shuwei Liu, Zhenping Li, Xiangtao Lin, Haiwei Meng, Cheng Liu, Lei Feng, Min Suk Chung, Dong Sun Shin, Eric Havet, Anne-Claire Dujardin, Fabrice Duparc, Pierre Freger, Anitha Oommen, Christoph Stosch, Jürgen Koebke, Stefan Herzig, Adam Jqbal, Paul Gazzani, Tim Rattay, Birgit Fruhstorfer, Anil Vohrah, Richard M. Wellings, Stephen Brydges, Gregory R. Smith, Jamie Roebuck, Peter H. Abrahams, Vaclav Baca, Michal Otcenasek, Filip Svatos, Tereza Smrzova, Robert Grill, David Kachlik, Jan Skubal, Valer Dzupa, Alena Doubkova, Ivo Klepacek, Josef Stingl, Muddathir Ali, Yahya Bedir, Günther Weber, Karim Malek, Amos Patrick, Brent Rochambeau, Phil Knickelbein, Da-Yae Choi, Mi-Sun Hur, Kwan-Hyun Youn, Kyung-Seok Hu, Hee-Jin Kim, Fadullah Aksoy, Yavuz Selim Yildirim, Orhan Ozturan, Hurtan Acar, Hasan Demirhan, Bayram Veyseller, Jean Michel Prades, Andrei Timoshenko, Alexander Asanau, Marie Gavid, Christian Martin, Benoit Ayestaray, Isabelle Auquit-Auckbur, Pierre-Yves Millez, Burcu Ercakmak, Alp Bayramoglu, Hakan Ozsoy, Deniz Demiryurek, Eray Tuccar, Keiichi Akita, Kumiko Yamaguchi, Atsuo Kato, Tomoyuki Mochizuki, Julien Beldame, Jean-Philippe Mure, Benjamin Lefebvre, David M. Lloyd, K. J. Karmand, M. G. Norwood, Aysin Kale, Ozcan Gayretli, Adnan Ozturk, Ilke Ali Gurses, Ahmet Usta, Kayihan Sahinoglu, Gokhan Kaynak, Mustafa Bilgili, Isik Akgun, Tahir Ogut, Mehmetcan Unlu, Ibrahim Uzun, Biagio Valentino, Elvira Farina, Tomoyasu Kato, Stoyan Pavlov, Maria Grosheva, Andrey Irintchev, Doychin Angelov, Tulin Sen, Ali Firat Esmer, S. Tuna Karahan, Benoit Delas, Jean Pierre Marie, Jean Christophe Sabourin, Anna Hebda, Rachel Claire Aland, Nihal Apaydin, Alparslan Apan, Aysun Uz, Ayhan Comert, Mehmet Arslan, Halil Ibrahim Acar, Mevci Ozdemir, Alaittin Elhan, Ibrahim Tekdemir, R. Shane Tubbs, Ayhan Attar, Hasan Caglar Ugur, Zeliha Fazliogullari, Ismihan Ilknur Uysal, Ahmet Kagan Karabulut, Nadire Unver Dogan, Muzaffer Seker, Neslihan Cankara, Mehmet Ali Malas, Emine Hilal Evcil, Aysegul Firat, Mine Erbil, Figen Kaymaz, Sinan Yuruker, Semiha Sen, Mina Tadjalli, Seid Reza Ghazi, Paria Parto, Seyed Reza Ghazi, Ceren Gunenc Beser, Musturay Karcaaltincaba, H. Hamdi Celik, Ruhgun Basar, Serpil Cilingiroglu, Cemal Ozbakir, Kenan Kose, Suleyman Tuna Karahan, Gulnur Ozguner, Osman Sulak, Irwin Best, Radovan Turyna, Ismail Malkoc, Huseyin Karagoz, Bilal Firat Alp, Cemal Gundogdu, Samih Diyarbakir, Firas Ghazi, Panagiotis Karanis, Sayee Rajangam, Preetha Tilak, Rema Devi, Bita Seifi, Naeem Earfani Majd, Mehran Dorstghol, Negar Niakan, Behpour Yousefi, Nooshin Bromand, Saeed Haghighi, Majid Malekzadeh Shafaroudi, Craig Daly, John Chris McGrath, Reza Ahadi, Mehrdad Bakhtiary, Mohammad Taghi Joghataei, Mehdi Mehdizadeh, Samideh Khoei, Mohsen Marzban, Parvin Salehinejad, Zahra Torshizi, Maryam Mohit, Nourjahan Banou Alithan, Ali Adulmanaf, Omar Abdulrahman, Seyed Adel Moallem, Bibi Ezzat Hosseini, Mohammad Afshar, Mohammad Mehdi Hasanzadeh Taheri, Javad Hami, Mohammad Hossein Davari, Saeid Kalbasi, Noroz Najafzade, Malihe Nobakht, Manoochehr Safari, Sara Asalgoo, Nahid Rahbar Roshandel, Mohamad Taghi Joghataeei, Mehrdad Bakhtiari, Farid Safar, Negin Salamat, Naeem Alboghobeish, Mahmood Hashemitabar, Mehrzad Mesbah, Ewa Biegaj, Tymon Skadorwa, Robert Kapolka, Bogdan Ciszek, Maria Piagkou, Giannoulis Piagkos, Vassiliki Kouki Aikaterini, Stergios Douvetzemis, Panagiotis Skandalakis, Sophia Anagnostopoulou, Mohamed Rashid Haffajee, Mohamed Adoobaker Ebrahim, J. W. Smith, Peter Osmotherly, Darren Rivett, Susan Mercer, Bin Yue, Dai-Soon Kwak, Yong-Seok Nam, Je-Hun Lee, U-Young Lee, Xiaochun An, Mi-Sun Lee, Seung-Ho Han, Ahmet Songur, Olcay Eser, Ozan Alkoc, Muhsin Toktas, Veli Caglar, Tuncay Kaner, Mehmet Tugrul Yilmaz, Serter Gumus, Isinman Ilknur Uysal, Yahya Paksoy, Mahinur Ulusoy, Mehmet Bulent Balioglu, Koray Savran, Gazi Zorer, Hitomi Fujishiro, Takeshi Muneta, Kenji Sato, Joël Vernois, Patrice Mertl, Bo Sun, Ge Haitao, Tang Yuchun, Zhonghe Zhang, Gaojun Teng, Hequn Geng, Taifei Yu, Umit S. Sehirli, Ural Verimli, Emel Ulupinar, Ferruh Yucel, Lia Neto, Edson Oliveira, Daniel Neto, Hugo Martins, Inácio Reis, Francisco Correia, António Goncalves Ferreira, Joana Regala, Paula Fernandes, Joana Teixeira, G. Nilufer Yonguc, M. Bulent Ozdemir, Vural Kucukatay, Melike Sahiner, Raziye Kursunluoglu, Esat Adiguzel, Ilgaz Akdogan, Yusuf Yilmaz, Melek Bor Kucukatay, Gulten Erken, M. Ayberk Kurt, Ilker M. Kafa, Murat Uysal, Sinan Bakirci, Suraj Prakash, Mahindra Kumar Anand, Meena Verma, Mohsen Basiri, Ronald Doucette, Yuchun Tang, Lingzhong Fan, Mehmet Dumlu Aydin, Canan Atalay, Sare Altas, Ednan Bayram, Bunyami Unal, Sahin Asian, Georg Feigl, Friedrich Anderhuber, Rainer Rienmuller, Jean Phillippe Guyot, Jean H. D. Fasel, Izabel Kos, Oguz Aslan Ozen, Mustafa Sarsilmaz, Gunnar Grant, Mohammad Reza Nourani, Zahra Jamali, Hamid Reza Taghipour, Yuji Owada, Mohammad Ali Khalili, Ben R. Clower, Morteza Anvari, Fatemeh Sadeghian, Farzaneh Fesahat, Seyd Mohsen Miresmaili, Bagher Pourheydar, Mohammad Taghi Joghataeei, Vahid Pirhajati, Abolfazl Faghihi, Fereshteh Mehraeen, S. Saeed Seyed Jafari, Abbas Aliaghaei, S. Noureddin Nematollahi-Mahani, Vahid Sheibani, Majid Asadi, Gholam Reza Kaka, Taki Tiraihi, Karol Budohoski, Jacek Kunicki, Ulrike Pilsl, Can Pelin, Baris Ozener, Ayla Kurkcuoglu, Ragiba Zagyapan, Anna Zurada, Jerzy Gielecki, Hakan Ay, Bruno Grignon, Frederic Walter, Toufik Batch, Horatiu Varlam, Iulian Iopincariu, Mehdi Benkhadra, Francois Lenfant, Pierre Trouilloud, Manuel Kastner, and Likar Rudolf
- Subjects
Entrapment ,business.industry ,Medicine ,Radiology, Nuclear Medicine and imaging ,Surgery ,Anatomy ,business ,Radial nerve ,Pathology and Forensic Medicine - Published
- 2009
- Full Text
- View/download PDF
4. Poster presentations
- Author
-
Funda Aksu, Hakan Topacoglu, Candan Arman, Aytul Atac, Suleyman Tetik, Aida Hasanovic, Amela Kulenovic, Zakira Mornjakovic, Branko Pikula, Aida Sarac-Hadzihalilovic, Alma Voljevica, Belgin Bamac, Tuncay Colak, Murat Alemdar, Gulmine Dundar, Macit Selekler, Ozgur Dincer, Enis Colak, Aydin Ozbek, Cenk Kilic, Kivanc Kamburoglu, Tuncer Ozen, Vatan Kavak, Yalcin Kirici, Emin Oztas, Handan Altinkaya Soysal, Erdogan Unur, Nihat Ekinci, Omur Karaca, Olga Malakhova, Murat Kocaoglu, Serdar Toker, Figen Taser, Volkan Kilincoglu, Mustafa Fahri Yurtgun, Cannur Dalcik, Ali Zeybek, Marc Baroncini, Johann Peltier, Patrice Jissendi, Jean-Pierre Pruvo, Jean-Paul Francke, Vincent Prevot, Rengin Kosif, Yasin Arifoglu, Murat Diramali, Mustafa Sarsilmaz, Evren Kose, Murat Ogeturk, Burhan Akpinar, Ilter Kus, Sedat Meydan, Alev Kara, Zeliha Kurtoglu, Ibrahim Tekdemir, Alaittin Elhan, Orhan Bas, Ersan Odaci, Hakan Mollaoglu, Kagan Ucok, Suleyman Kaplan, Mehmet Senoglu, Vedat Nacitarhan, Ergul Belge Kurutas, Nimet Senoglu, Idris Altun, Yalcin Atli, Davut Ozbag, Sacide Karakas, M. Dincer Bilgin, Ayfer Metin Tellioglu, Sercin Ozlem, Betul Akcanal, Yuksel Yildiz, Hakki Gunes, Hayrullah Kose, Ibrahim Uzum, Umit Naci Gundogmus, Cigdem Caglayan, Velichka Pavlova, Mashenka Dimitrova, Lilia Georgieva, Elena Nikolova, Deniz Uzmansel, Nail Can Ozturk, Canan Yurttas Saylam, Erkin Ozgiray, Mustafa Orhan, Sedat Cagli, Mehmet Zileli, Derya Ozkan, Taylan Akkaya, Ayhan Comert, Nilgun Balikci, Esra Ozdemir, Haluk Gumus, Zafer Ergul, Oskay Kaya, Serdar Altun, R. Erkin Unlu, Hakan Orbay, Deog-Im Kim, Seung-Ho Han, Yi-Suk Kim, Ho-Jeong Kim, Kyu-Seok Lee, Omur Elcioglu, Hilmi Ozden, Gul Guven, Nurcan Imre, Bulent Yalcin, Hasan Ozan, Pinar Akyer, Mustafa Guvencer, Vasfi Karatosun, Mandeep Gill Sagoo, Rachel Claire Aland, Derya Ustuner, M. Cengiz Ustuner, Jafar Ai, Seyed Reza Ghazi, Seyed Hadi Mansouri, Mehmet Cudi Tuncer, Mehmet Ufuk Aluclu, Ozlen Karabulut, Eyup Savas Hatipoglu, Hasan Nazaroglu, Cigdem Icke, Emrah Akbay, Turkan Gunay, Suleyman Icke, Selda Yildiz, Fatih Yazar, Barcin Orhan Barlas, Delia Elena Zahoi, Ahmet Kavakli, Ufuk Tas, Durrin Ozlem Dabak, Hilal Irmak Sapmaz, Necdet Kocabiyik, Cenk Murat Ozer, Ayhan Ozcan, Levent Elevli, Kadir Desdicioglu, Ibrahim Alanbay, Figen Govsa, Canan Y. Saylam, Ilgaz Akdogan, Yilmaz Kiroglu, Sule Onur, Emine Hilal Evcil, Neslihan Cankara, Mehmet Ali Malas, M. Tayyar Kalcioglu, Serdar Duman, Tufan Ulcay, Ahmet Uzun, Zulfu Karabulut, Cagatay Barut, Ozdemir Sevinc, Gamze Yurdakan, Dundar Kacar, Ali Riza Erdogan, Hulyam Kurt, Bunyamin Demir, Mustafa Saltan, Dilek Burukoglu, Mehmet Cengiz Ustuner, Irfan Degirmenci, Aliriza Erdogan, Ozlem Damar, Merih Is, Gokhan Bayramoglu, Sahin Kabay, Onur Uysal, Hakan Senturk, Aysegul Bayramoglu, Cansu Ozbayar, Ali Kutlu, Mediha Canbek, Salih Cenap Cevli, Oguz Hancerlioglu, Mustafa Koplay, Elif Aksakalli, Fatih Dikici, Aysin Kale, Ozcan Gayretli, Ilke Ali Gurses, Senem Turan Ozdemir, Ilker Ercan, Emel Bulbul Baskan, Mediha Yilmaz, Guven Ozkaya, Hayriye Saricaoglu, Mete Erturk, Gulgun Kayalioglu, Mehmet Uzel, Guler Kahraman, Ercan Tanyeli, Ali Ihsan Soyluoglu, Orhan Tacar, Ayda Demirant, Murat Bilgin, Aziz Karadede, Ayfer Aktas, E. Hilal Evcil, Esra Koyuncu, Osman Sulak, Soner Albay, Gulnur Ozguner, Ahmet Ozbek, Elvan Ozbek, A. Hakan Ozturk, Tuba Demirci, Engin Ciftcioglu, Mehmet Tevfik Demir, Cem Kopuz, Esra Eroglu, Semin Gedikli, Hamit Ozyurek, Mehmet Selim Nural, Lutfi Incesu, Gonul Ogur, Engin Kara, Baris Celebi, Altan Yildiz, B. Zuhal Altunkaynak, Samet Vasfi Kuvat, Suleyman Murat Tagil, Cumhur Ertekin, Hilmi Uysal, Fikret Bademkiran, Nural Albayrak, Ali Firat Esmer, Nigar Keles Coskun, Muzaffer Sindel, Ferah Kizilay, Sevket Yalin, Nevin Karapinar, Mehmet Tokdemir, Lokman Karakurt, Levent Tumkaya, Adnan Korkmaz, Bulent Ayas, Nusret Ciftci, Yuksel Terzi, Ozlem Baran, Yusuf Nergiz, Murat Akkus, Ufuk Aluclu, Askin Ender Topal, Dilek Yuksel, Halil Ibrahim Acar, Simel Kendir, Emre Hekimoglu, Deniz Basman, Sunay Duman, Baris Ozener, Can Pelin, Ragiba Zagyapan, Ayla Kurkcuoglu, Mustafa Koc, Meral Erdinc, Levent Erdinc, Ilker Kelle, Enver Sancakdar, Nil Cetin, Selcuk Tunik, Ayse Yildirim, Iskender Kaplanoglu, Ercan Ayaz, Necip Ilhan, Mehmet Okumus, Kasim Zafer Yuksel, Harun Ciralik, Zeki Yilmaz, Yakup Gumusalan, Mehmet Gamsizkan, Mustafa Kazkayasi, Nadire Unver Dogan, Ismihan Ilknur Uysal, Aylin Karalezli, Zeliha Fazliogullari, Mustafa Buyukmumcu, Mehmet Cem Bozkurt, Aynur Emine Cicekcibasi, Deniz Demiryurek, M. Hakan Ozsoy, Alp Bayramoglu, Eray Tuccar, Ozlem Pamukcu Baran, Sevda Soker, Selen Bahceci, Yasemin Nasir, Mehmet Tugrul Yilmaz, Emine Aynur Cicekcibasi, Mahinur Ulusoy, Pervin Gunaslan, Nuray Bilge, Muzaffer Akkaya, Abdurrahman Genc, Sezer Akcer, Yucel Gonul, Emine Cosar, Gulengul Koken, Ilknur Ari, Sinan Bakirci, Ilker Mustafa Kafa, Murat Uysal, Ahmet Kagan Karabulut, Bahar Keles, Dilek Emlik, Yavuz Uyar, Kayhan Ozturk, Neslihan Altuntas Yilmaz, Ahmet Salbacak, Burkay Kutluhan Kacira, Mehmet Arazi, Serafettin Demirci, Demet Kiresi, Serter Gumus, Muzaffer Seker, Mehmet Uyar, Mohammad Ebrahim Astaneh, Alireza Khorshid, Ramazan Uygur, Ahmet Songur, Osman Fikret Sonmez, Kamil Hakan Dogan, Giray Kolcu, Madalina Iliescu, Petru Bordei, Dan Iliescu, Camelia Ciobotaru, Viorel Lucescu, Anatoli Covaleov, Constantin Ionescu, Miguel Guirao, E. Páramo, R. Mutuberria, I. Sánchez-Montesinos, O. Roda, F. Girón, Miguel Lopez-Soler, Olga Roda, Raúl Campos-López, Miguel Guirao-Piñeiro, Maria Teresa Pascual-Morenilla, Indalecio Sanchez-Montesinos, Maria Teresa Pascual, I. Garzon, D. Serrato, R. Nieto-Aguilar, I. Sanchez-Montesinos, M. Sanchez-Quevedo, M. Bulent Ozdemir, R. Hakan Ozean, Dilek Bagdatli, Esat Adiguzel, Zumrut Dogan, Ozlem Aycan, Nigar Vardi, Haldun Sukru Erkal, Hakan Ozturk, S. Mocanu, C. Stefanescu, A. Ionescu, Raluca Talpes, Elena Sapte, Constantin Dina, Loredana Surdu, Ionut Bulbuc, M. T. Medina, J. Medina, M. López-Soler, Carlos Martin-Oviedo, Alejandro Lowy-Benoliel, Eva Maranillo, Tomas Martinez-Guirado, Jose Sañudo, Bartolome Scola, Teresa Vazquez, L. A. Arráez-Aybar, J. L. Conejo-Menor, C. C. Gonzáles-Gómez, A. J. Torres-García, Hisayo Nasu, Shoji Chiba, M. Gutierrez-Semillera, Yahya Paksoy, Ahmet Kalaycioglu, Mehmet Yildirim, Ali Ozyasar, Omer Ozdogmus, Yusuf Ozgur Cakmak, Ural Verimli, Safiye Cavdar, Begum Yildizhan, Z. Asli Aktan Ikiz, Hulya Ucerler, Zuhal Ozgur, Seher Yilmaz, Abdullah Demirtas, Ertugrul Mavili, Mehtap Hacialiogullari, Hatice Susar, Seda Arslan, Kenan Aycan, Vecihi Ozkaya, Mara Pilmane, Sarmite Boka, Gursel Ortug, Carlos Ramirez, Aran Pascual-Font, Francisco Valderrama-Canales, Abdulah Kucukalic, Eldan Kapur, Elvira Talovic, Vaclav Baca, Robert Grill, Zdenek Horak, David Kachlik, Valer Dzupa, Marek Konarik, Jakub Knize, Petr Veleminsky, Tereza Smrzova, Michal Otcenasek, Jana Chmelova, Michal Kheck, Tomas Cupka, Lukas Hnatek, Floris van der Meijs, Pavel Cech, Vladimir Musil, H. Mustafa Ozkan, S. Kivanc Muratli, Hamid Tayefi, Ipek Ergur, Amac Kiray, Muhsin Toktas, Ozan Alkoc, Tolgahan Acar, Ibrahim Uzun, Oguz Asian Ozen, Abdullah Aycicek, Ozan Alper Alkoc, Mehmet Unlu, Ufuk Corumlu, Ihsaniye Coskun Ikiz, I. Hakan Oygucu, Erdogan Sendemir, Tuncay Kaner, Veli Caglar, Olcay Eser, Mehmet T. Demir, Omer Iyigun, Gokhan Pirzirenli, Ahmet Hilmi Kaya, Mennan Ece Aydin, Fahrettin Celik, Hakan True, Sevket Ozkaya, Bekir Ugur Ergur, Gulsah Zeybek, Kadir Bacakoglu, Mina Tadjalli, Aghdas Poostpasand, Seid Hadi Mansouiri, Ozra Allahvaisi, Jafar Soleimanirad, Bahram Nikkhoo, Yasukazu Nagato, Yasuo Haruki, Komazo Yazawa, Tutomu Okazaki, Munetaka Haida, Yutaka Imai, Thmineh Peirouvi, Mehrzad Mahzad-Sadaghiani, Farahnaz Noroozinia, Salami Siamak, Gholamhosseine Farjah, Sima Mola, Ewa Biegaj, Tymon Skadorwa, Konrad Pawlewicz, Robert Kapolka, Agata Chachulska, Joanna Zabicka, Aleksandra Krasowska, Alicja Prusik, Grzegorz Jaczewski, Adam Kolesnik, M. Mohsen Taghavi, S. Hasan Alavi, S. Adel Moallem, Zahed Safikhani, Marzieh Panahi, Shahriar Dabiri, Majid Asadi Shekaari, Rafael Latorre, Federico Soria, Octavio Lopez-Albors, Ricardo Sarria, Inacio Ayala, Inma Serrano, Enrique Perez-Cuadrado, Vladimir Musienko, Dmitry Tkachenko, Neriman Colakoglu, Murat Abdulgani Kus, Mahdi Jalali, Mohammad Reza Nikravesh, Abbas Ali Moeen, Mohammad Hassan Karimfar, Houshang Rafighdoost, Shabnam Mohammadi, Marina Korneeva, Houshang Rafighdoust, Kvetuse Lovasova, Adriana Bolekova, Darina Kluchova, Igor Sulla, Marina Yurievna Kapitonova, Syed Baharom Syed Ahmad Fuad, Flossie Jayakaran, Ali Reza Shams, Fereshteh Aghaee, Zohreh Baqer, Mohamad Faroki, Srijit Das, Normadiah Kassim, Azian Latiff, Frihah Suhaimi, Norzana Ghafar, Khin Pa Pa Hlaing, Israa Maatoq, Faizah Othman, Muge Kiray, Husnu Alper Bagriyanik, Cetin Pekcetin, Candan Ozogul, Mustafa Fidan, Farihah Suhaimi, Fei Sun, Francisco Sanchez-Margallo, Francisco Gil, Verónica Crisostomo, Jesus Uson, Gegorio Ramirez, Ozan Turamanlar, Oguz Kirpiko, Alpay Haktanir, Salvador Climent, Sergio Losilla, Maria Climent, Levent Sarikcioglu, Yesim Senol, Fatos B. Yildirim, Arzu Utuk, Jacek Kunicki, Parichehr Pasbakhsh, Negar Omidi, Hamed Omidi, Fatemeh Dehghani Nazhvani, Seyed Razi Ghalebi, Nima Javan, Akrami Mohagery, Ali Reza Ebrahimzadeh Bideskan, Mohammad Mehdi Hassanzadeh Taheri, Ali Reza Fazel, Cesare Tiengo, Veronica Macchi, Carla Stecco, Andrea Porzionato, Franco Mazzoleni, Raffaele De Caro, Alberto Clemente, Aldo Morra, Pietro Greco, Piero Pavan, Arturo Natali, Mehmet Demir, Mehmet Dokur, Niyazi Acer, Ayfer Mavi, Niki Matveeva, Dobrila Lazarova, Kostandina Korneti, Svetlana Jovevska, Dragica Jurkovik, Meri Papazova, Masoumeh Havasi, Naeim Alboghobeish, Ahmad Savari, Negin Salamat, Mozafar Sharifi, Hyun-Ho Kwak, Kyung-Seok Hu, Gyoo-Cheon Kim, Bong-Soo Park, Hee-Jin Kim, Ahmet Sinav, Adarsh K. Gulati, Nidhi K. Gulati, Hussien Alshammary, Seifollah Dehghani Nazhvani, Amir Vafafar, Tahereh Esmaeilpour, Soghra Bahmanpour, Leila Elyasi, Ahmad Monabbati, M. Ghanadi, Mohammad Reza Paryani, Hassan Gilanpour, Banino Amirsam, Rodrigo Elizondo Omaña, Santos Guzmán López, Oscar De la Garza Castro, Edgar Urrutia Vega, Santos Guzman Lopez, Freshteh Talebpour, Rahim Golmohammadi, Golamreza Dashti, Mohammad Ali Atlasi, Mehdi Mehdizadeh, Mohammad Hadi Bahadori, Mohammad Taghi Joghataei, Leili Hatami, Mandana Beigi Boroujeni, Jasem Estakhr, Ebrahim Esfandiary, Mohsen Marzban, Mehrdad Bakhtiary, Navid Modiry, Mokhtar Jafarpur, Hassan Mofidpur, S. Hassan Alavi, Alareza Mahmoudian, Mohmmad Mohsen Taghavi, Mokhtar Jafarpour, Ali Reza Mahmoudian, Nasrin Sanjarmousavi, Ines Doassans, Natalia Sorrenti, German Decuadro, Andres Saibene, Marie Poumayrac, Sebastian Laza, Carina Almiron, Maria Elena Vergara, Victor Soria, Sebastian Lasa, Adolfo Perez, Gabriela Castro, Ana Santa Maria, Mansoureh Soleimani, Majid Katebi, Masoomeh Bakhshayesh, Mithat Oner, Mehmet Halici, Ali Yikilmaz, Ahmet Guney, Yildirim Turk, Mete Edizer, Umit Beden, Nihal Icten, Mohammad Afshar, Mohammad Mehdi Hasanzadeh Taheri, Adel Moalem, Mohammad Jafar Golalipour, Azadeh Tamizi, Mohammad Ahi, Shahram Mohammadpour, Ardeshir Maiery, Cengiz Acikel, Ersin Ulkur, Huseyin Karagoz, Bahattin Celikoz, Kuldip Bedi, Partadiredja Ginus, Mohammad Jafar Golalipoor, Mohammad Reza Mohammadi, Poya Jhand, Azad Reza Mansourian, Kanizreza Hosseinpoor, Abbas Ali Keshtkar, Raith Alsaffar, Babak Kabiri Balajadeh, Soraya Ghafari, Ramin Azarhosh, Seyyed Amirhossein Fazeli, Mehrdad Jahanshahi, Annen Mohammad Gharravi, Banu Alicioglu, Hakki Muammer Karakas, Ahmet Harma, Hun-Mu Yang, Sung-Yoon Won, Jae-Gi Lee, Ju-Young Lee, Jeong-Yong Lee, Yoo-Ri Kim, Wu-Chul Song, Ki-Seok Koh, Eu-Na Hwang, Hyun-Gon Choi, Soon-Heum Kim, Soo-Young Kim, Mi-Sun Hur, Enis Ulucam, Osman Celbis, Da-Hye Kim, Hee-Suk Hong, Hyun-Joo Kim, Jong-Hoon Choi, Jong-Tae Park, Hyeon-Cheol Kim, Hamed Abbasi, Seyed Mohammad Hosseinipanah, Mohammad Hosseini, A. Amani, H. R. Ashrafi, Mohsen Sadeghimehr, Hyun-Ju Kim, Vadim Sheverdin, Zahra Amani, Alireza Ashrafi, Ali Reza Ashrafi, Hami Javad, Mokhtar Jafarpoor Kachap, Sebastián Laza, Marie Catherine Poumayrac, Inés Doassans, María Elena Vergara, Carina Almirón, Víctor Soria, Alvaro Rivara, Angela Sirilo, Diego Freire, Angela Cirillo, Maria Elena Veragara, Vlado Krmek, Nikola Krmek, Ana Jo-Osvatic, Vasilije Nikolic, Radivoje Radic, R. Shane Tubbs, Marios Loukas, Quentin Fogg, Neil Ashwood, Serpil Cilingiroglu, Cemal Ozbakir, Tahereh Mazoochi, Vedat Sabanciogullari, Cesur Gumus, F. Hayat Erdil, Mehmet Cimen, Hesam Moodi, Fateme Ghiasi, Asghar Akbari, Javad Hami, Majid Khazei, Elham Haghparast, Ioannis Mitsakis, Aikaterini Anastasiou, Menelaos Mitsakis, Kyriaki Sianou, Roxani Hainoglou, Margarida Francisco, Charikleia Mitsaki, Maria Konstantinidi, Stamatia Prapa, Igor Leksan, Tomislav Mrcela, Robert Selthofer, Fatemeh Kermanian, Alireza Mahmoudian, Mahmood Erfanian Ahmadpoor, Naser Dalili, Amir Hossein Elian, Ardesheer Moaiery, Zahra Jamalpour, Mohammad Reza Nourani, Alireza Asgari, Alireza Ebrahimzadeh, Seyed Hasan Eftekharvaghefi, Abbas Mohammadi, Vahid Sheibani, Seyed Noureddin Nematollahi-Mahani, Mastafa Latifpour, Masood Deilami, Behzad Soroure-Azimzadeh, Fatemeh Nabipour, Hamid Najafipour, Nouzar Nakhaee, Mohammad Yaghoobi, Rana Eftekharvaghefi, Parvin Salehinejad, Hasan Azizi, Hamid Reza Riasi, Maliheh Nobakht, Sara Asalgoo, Roshanak Rahbar, Norooz Najafzadeh, Kazem Moosavizadeh, Massood Ezzatabadypour, Masoud Majidi, Reza Malekpor-Afshar, Fariba Karimzade, Mahmood Hoseini, Mohamad Bayat, Ali Gorgi, Akram Nezhadi, Mehrdad Bakhtiari, Homa Rasooli Jazi, Maryam Jafaryan, Hosein Haghir, Mahmood Hosseini, Sadegh Rahimi, Fatemeh Behnam Rassouli, Ali Gorji, Aliasghar Habibi, Fatemeh Pouya, Shahryar Dabiri, A. Mousavi, Saeed Rajabalian, A. Abolidokht, Neda Khanlarkhani, Homayoun Naderian, Nezamedin Berjis, Mohamad Reza Namavar, Tahereh Talaei, Zohreh Mazaheri, Ahmad Monabati, Mehmet Ilkay Kosar, Kezban Karacan, Hamidreza Chegini, Hossein Nikzad, Egemen Ayhan, Sinan Ustundag, Salih Murat Akkin, Tahir Ogut, Parviz Rayegan, Mohamad Ali Emami Meibodi, Reza Montazer Ghaem, Rosa Zargarpoor, Seyd Hasan Eftekhar Vaghefi, Ghazale Moshkdanian, Fateme Poya, Hamid Kohestani, Roozbeh Rayegan Abarghoeai, Parviz Rayegan Abarghoeai, Seyed Hasan Eftekhar Vaghefi, Abolghasem Amir Mahmodi, Ali Poraboli, Hamid Reza Kohestani, Raena Eftekhar Vaghefi, Seyed Hasan Eftekhar Vaghefy, Raena Eftekhar Vaghefy, Parviz Raygan Abarghoeai, Mohamad Saba, Anneh Mohammad Gharravi, Fatemeh Javadnia, Mohsen Zhaleh, Dariush Bijan Nezhad, Mohammad Reza Gholami, Maria Piagkou, Vassiliki Kouki Aikaterini, Giannoulis Piagkos, Stergios Douvetzemis, Panagiotis Skandalakis, Sophia Anagnostopoulou, Nikolaos Papadopoulos, H. Hamdi Celik, Ilkan Tatar, Emel Cadalli Tatar, Burce Ozgen Mocan, Mustafa F. Sargon, C. Cem Denk, Homa Rasoolijazi, Mohammad Taghi Joghataie, Mehrdad Roghani, Salin Murat Akkin, Gulten Dinc, Mustafa Kurklu, Sener Ozboluk, Mahmut Komurcu, Jürgen Koebke, Mehmet Bulent Balioglu, Mehmet Akif Kaygusuz, Ferdi Sefa Bozkus, Ozgur Korkmaz, Sule Biyik Bayram, Mehmet Ali Can, Ebrahim Nasiri, Koroush Jafar-Kazemi, Melina Hosseini, Shahin Maghoul, Mansooreh Soleimani, Abdollah Amini, Mohamad Mahdi Hassanzade, Mohammad Hossein Davari, Tom Van Hoof, Germano T. Gomes, Emmanuel Audenaert, Koenraad Verstraete, Ingrid Kerckaert, Katharina D’Herde, Brion Benninger, Gil Hedley, Florin Mihail Filipoiu, Eugen Tarta, Mihali Enyedi, Cosmin Pantu, Razvan Stanciulescu, Cezary Skobowiat, Jaroslaw Calka, Mariusz Majewski, Maryam Rezaian, Akbar Yaghoobfar, Somayeh Hamedi, and T. Shomali
- Subjects
Radiology, Nuclear Medicine and imaging ,Surgery ,Anatomy ,Pathology and Forensic Medicine - Published
- 2009
5. Penicillin-induced epilepsy model in rats: Dose-dependant effect on hippocampal volume and neuron number
- Author
-
Ilgaz Akdogan, Esat Adiguzel, A. Cevik Tufan, Ismail Yilmaz, M. Bulent Ozdemir, and Melike Şahiner
- Subjects
hippocampus ,Neuron number ,Hippocampus ,Cell Count ,Hippocampal formation ,Rats, Sprague-Dawley ,Epilepsy ,Random Allocation ,Status Epilepticus ,dose response ,rat ,Neurons ,General Neuroscience ,Pyramidal Cells ,article ,pyramidal nerve cell ,Electroencephalography ,Penicillin G ,Organ Size ,Dose–response relationship ,medicine.anatomical_structure ,female ,priority journal ,Anesthesia ,sodium chloride ,neuroprotection ,Epileptic seizure ,Pyramidal cell ,medicine.symptom ,nerve cell ,medicine.medical_specialty ,seizure ,animal experiment ,Neuroprotection ,animal tissue ,Internal medicine ,medicine ,Animals ,Experimental epilepsy ,controlled study ,nonhuman ,Dose-Response Relationship, Drug ,business.industry ,Volume ,animal model ,medicine.disease ,Penicillin ,Rats ,Disease Models, Animal ,Endocrinology ,Neuron ,business - Abstract
This study was designed to evaluate the penicillin-induced epilepsy model in terms of dose-response relationship of penicillin used to induce epilepsy seizure on hippocampal neuron number and hippocampal volume in Sprague-Dawley rats. Seizures were induced with 300, 500, 1500 and 2000 IU of penicillin-G injected intracortically in rats divided in four experimental groups, respectively. Control group was injected intracortically with saline. Animals were decapitated on day 7 of treatment and brains were removed. The total neuron number of pyramidal cell layer from rat hippocampus was estimated using the optical fractionator method. The volume of same hippocampal areas was estimated using the Cavalieri method. Dose-dependent decrease in hippocampal neuron number was observed in three experimental groups (300, 500 and 1500 IU of penicillin-G), and the effects were statistically significant when compared to the control group (P < 0.009). Dose-dependent decrease in hippocampal volume, on the other hand, was observed in all three of these groups; however, the difference compared to the control group was only statistically significant in 1500 IU of penicillin-G injected group (P < 0.009). At the dose of 2000 IU penicillin-G, all animals died due to status seizures. These results suggest that the appropriate dose of penicillin has to be selected for a given experimental epilepsy study in order to demonstrate the relevant epileptic seizure and its effects. Intracortical 1500 IU penicillin-induced epilepsy model may be a good choice to practice studies that investigate neuroprotective mechanisms of the anti-epileptic drugs. © 2008 Elsevier Inc. All rights reserved.
- Published
- 2008
- Full Text
- View/download PDF
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.