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Background: Sentinel Lymph Node Biopsy is a technique developed to predict lymphatic involvement in patients with early endometrial cancer, decreasing the morbimortality associated with routine systematic lymphadenectomy and improving quality of life. Main Objective: To determine the detection rate and negative predictive value of the Sentinel Lymph Node Biopsy by Immunofluorescence in patients with early endometrial cancer. Methods: A descriptive observational study in patients with early endometrial cancer (FIGO stage I-II) for all histological types and grades, who underwent the Sentinel Lymph Node by immunofluorescence Technique, between June 2019 and March 2020 at the Fundación Jiménez Díaz University Hospital. We used indocyanine green powder for injection, with a concentration of 25 milligrams (mg). We proceeded to dissolve it in 10 cubic centimeters (cc) of distilled water to. After which, we injected 2 cc of the prepared solution into the cervix at the 3 and 9 o’clock positions at a depth of 1 centimeter. Results: Eighteen patients were included, analysing a total of 26 sentinel nodes: 24 pelvic and 2 paraortic; and a total of 273 lymph nodes (sentinel and non-sentinel nodes): 83 right pelvic, 86 left pelvic and 104 paraortic. All nodes were negative for metastasis. Global and bilateral detection rates were 77.78% and 50% respectively. The Negative Predictive Value and sensitivity were 100%. No significant difference in morbimortality was found between performing only Sentinel Lymph Node technique or systematic lymphadenectomy, but the association with quality of life was significant, with better results for those who only underwent the sentinel lymph node technique versus systematic lymphadenectomy (0% vs 77%). Conclusion: The global and bilateral detection rates of the Sentinel Lymph Node Technique by immunofluorescence were 77.78% and 50% respectively, obtaining a Negative Predictive Value and Sensitivity of 100%. Sentinel Node Biopsy is a valid technique to predict lymphatic affectation in early endometrial cancer, with lower morbimortality than systematic lymphadenectomy.

Situasi pertumbuhan kasus Covid-19 sangat cepat di Indonesia. Upaya pencegahan yang dilakukan oleh tim Kuliah Kerja Nyata dari Sekolah Tinggi Teknologi Garut menjadi salah satu solusi dalam upaya pencegahan karena sampai saat ini belum ada obat untuk penyakit ini. Pencegahan yang dapat dilakukan berupa sosialisasi yang dilakukan dengan menerapkan etika batuk serta melalui perlindungan khusus yang dilakukan dengan cara menggunakan dan bagi bagi masker, membersihkan tangan dan social distancing. Pada masa pandemi covid-19 juga, setiap individu perlu menguasai bahwa literasi digital merupakan hal penting yang dibutuhkan untuk dapat berpartisipasi di dunia modern dan mengantisipasi penyebaran informasi negatif pada masa pandemi covid-19. Literasi digital akan menciptakan tatanan masyarakat dengan pola pikir dan pandangan yang kritis dan kreatif. Artikel ini hasil dari gerakan literasi digital yang dapat dilakukan pada masa pandemi covid-19 adalah gerakan literasi digital bagi pelajar dan masyarakat. Gerakan literasi tersebut bertujuan untuk meningkatkan kemampuan berpikir kritis, kreatif dan positif dalam menggunakan media digital dalam kehidupan sehari-hari. Artikel ini juga menawarkan konsep antisipasi berita hoaks pada masa pandemi covid-19. Literasi teknologi mencakup segala pengetahuan dan keterampilan dalam memanfaatkan teknologi, mulai dari mengenal perangkatnya, mengoperasikannya, mengolah dan mengkomunikasikan informasi sehingga masyarakat memiliki pengetahuan yang lebih baik akan hal tersebut.

Introduction/Background* Sentinel Lymph Node Biopsy is a technique developed to predict lymphatic involvement in patients with early endometrial cancer, decreasing the morbimortality associated with routine systematic lymphadenectomy and improving quality of life. Methodology Main Objective To determine the detection rate and negative predictive value of the Sentinel Lymph Node Biopsy by Immunofluorescence in patients with early endometrial cancer. Method A descriptive observational study in patients with early endometrial cancer (FIGO stage I-II) for all histological types and grades, who underwent the Sentinel Lymph Node by immunofluorescence Technique and/or systematic lymphadenectomy between June 2019 and March 2020 at the Fundacion Jimenez Diaz University Hospital. We used indocyanine green powder. We proceeded to dissolve it in 10 cubic centimeters of distilled water. After which, we injected 2 cc of the prepared solution into the cervix at the 3 and 9 o’clock positions at a depth of 1 cm. Result(s)* Eighteen patients were included, analyzing a total of 26 sentinel nodes: 24 pelvic and 2 paraortic; and a total of 273 lymph nodes (sentinel and non-sentinel nodes): 83 right pelvic, 86 left pelvic and 104 paraortic. All nodes were negative for metastasis. Global and bilateral detection rates were 77.78% and 50% respectively. The Negative Predictive Value and sensitivity were 100%. No significant difference in morbimortality was found between performing only Sentinel Lymph Node technique or systematic lymphadenectomy; but the association with quality of life was significant, with better results for those who only underwent the sentinel lymph node technique versus systematic lymphadenectomy (0% vs 77%). However, we observed at the beginning of the study, bilateral detection was very limited. This could be due to a failure in the tracer injection technique in our first 10 patients. Because since from the standardization of the technique we obtained a considerable improvement in bilateral detection; 87.5% (before technical standardization 20%). This supports the theory that technique is the most important factor in detection (Rossi, 2019). Conclusion* The global and bilateral detection rates of the Sentinel Lymph Node Technique by immunofluorescence were 77.78% and 50% respectively, obtaining a Negative Predictive Value and Sensitivity of 100%. Sentinel Node Biopsy is a valid technique to predict lymphatic affectation in early endometrial cancer, with lower morbimortality than systematic lymphadenectomy

Resumen El linfoma anaplasico de celulas grandes asociado a implantes mamarios (BIA-ALCL segun sus siglas en ingles) es un tipo raro de linfoma no Hodgkin que se ha descrito en el contexto de la cirugia reconstructiva y estetica de mama mediante implantes. Este segundo articulo presenta la parte del consenso de la Sociedad Espanola de Senologia y Patologia Mamaria (SESPM) sobre el tratamiento quirurgico, medico, radioterapico, pronostico y seguimiento.

Resumen El linfoma anaplasico de celulas grandes asociado a implantes mamarios (BIA-ALCL segun sus siglas en ingles) es un tipo raro de linfoma no Hodgkin que se ha descrito en el contexto de la cirugia reconstructiva y estetica de mama mediante implantes. Estos articulos presentan un consenso de la Sociedad Espanola de Senologia y Patologia Mamaria (SESPM) con la idea de unificar, en esta primera parte, los criterios de diagnostico de esta enfermedad describiendo asimismo la epidemiologia y la etiopatogenia.

This paper examines how the views of Joseph Schacht is an orientalist scholar in the field of Islamic law who has done a lot of hadith criticism. Through his work, The Origins of Muhammadan Jurisprudence, Schacht states that the hadiths were made by scholars of the second and third centuries of hijra because in the past the hadiths had not been well codified. The view of this student of Ignaz Goldziher towards the hadith was developed by three theories, namely, the projecting back theory, the theory of argumentum e silentio, and the common link theory .

Introduction/Background Importance of adequate hemostasis and precision in vascular and nervous ganglionar surgery. Methodology We present a case of a patient with adenopathies larger than 2 cm on the superior mesenteric artery, interaortocaval and adhered to the obturator nerve, which are completely resected. Results The entire disease has been removed by practicing debulking surgery. Conclusion Knowledge of the anatomy to perform better surgery. Disclosure Nothing to disclose

Introduction/Background Realizacion de video de cirugia laparoscopica en que se muestra la importancia de una adecuada identificacion de estructuras en la linfadenectomia aortica y pelvica. Methodology Video production of laparoscopic surgery showing the importance of an adequate identification of structures in aortic and pelvic lymphadenectomy. In this systematic way it is possible to save unexpected structures or anatomical malformations. Results This video shows retroaortic renal vein, double obturator nerve, left ovarian vein towards vena cava, high obturator vein, crown of death vein, lateral inferior mesenteric artery... Conclusion the importance of reviewing images available preoperatively is essential, as well as performing systematic surgery step by step Disclosure Nothing to disclose

Introduction/Background LACC trial has changed the paradigm regarding the surgical treatment of cervical cancer. This is the first prospective study performed in this field and in which a better prognosis has been observed in patients treated by laparotomy. Methodology This is a retrospective observational cohort study without a control group. Inclusion criteria Patients with stages Ia1 (with lymphovascular invasion) to IIa1 treated by hysterectomy and trachelectomy including lymphadenectomy between January 2007 and December 2018 at the Jimenez Diaz Foundation Hospital. Exclusion criteria Patients under 18 years Pregnant patients. Older than 80 years. Surgical contraindications. ECOG ≤50% and/or ASA ≥4 Parametrial involvement All patients who met the described inclusion criteria were selected and different clinical parameters were analyzed, including age, menopausal status, physical examination for assessment of parameter involvement. Likewise, anatomopathological characteristics were studied, such as histological type, tumor size, lymphovascular invasion, parametrial infiltration, nuclear grade, stromal infiltration. The disease-free interval was also studied, as well as the overall survival. Results For all the patients recruited, a total of 84 of them were included in the inclusion criteria. The average age of the patients was 46 years (Minimum 27 and Maximum 70 years). 53 patients studied were in stage IB1 (63%), 14 stage IA1 (16.6%), 12 stage IA2 (14.3%) and 5 stage IIA1 (5.9%). The disease-free survival studied has been up to> 5 years. There have been a total of 5 recurrences (Minimum 8 and maximum 40 months). Conclusion The percentage of relapse and survival is in accordance with the current data. Laparoscopic surgery presents an acceptable complication rate. It is important to highlight the number of patients with tumors smaller than 2cm and without other associated risk factors that could have been operated on by type A radical hysterectomy and thus avoid the potential adverse effects of a more extensive surgery. Disclosure Nothing to disclose.

Telemedicine has helped to make health care more efficient. However, to date no studies have measured its impact on infertility and fertility healthcare. We assessed the potential care benefits and clinical advantages of an initiative implementing electronic patient portal (EPP) for patients scheduled to undergo assisted reproduction treatment, to reduce waiting times for medical consultation and treatment.This was designed as a retrospective cohort study. The experimental group comprised 1972 referral requests received by the assisted reproduction unit of our institution between 2015 and 2016, which were included in the group receiving telemedicine, while the control group was defined by 283 requests received in 2013, all of which were assigned face-to-face care.We found a statistically significant reduction in the experimental group in terms of the days elapsed between the receipt of the assessment request and the first outpatient visit (68 days vs. 180 days, p.001). Time to initiation of treatment was also significantly lower in this group (169 days vs. 229 days; p.001). The experimental group contained around 7 times as many patients receiving treatment as the control group. No differences were observed in the pregnancy rate (29.9% vs. 31.1%; p=.77) or in the complication rate (3.2% vs. 0%; p=.16).Use of telemedicine in electronic portal patient form reduces the total waiting time involved in patient requests for infertility treatment and indirectly increases the number of patients treated, causing no negative impact on treatment outcome.

The Pamela apparatus will allow precise measurements of cosmic rays in Low Earth Orbit, mainly focusing on the antiparticles component. The apparatus is now ready for flight, and the launch is foreseen during June 2006. The paper briefly reports the status of the experiment, and the performances of the various components as measured before the launch.

Subcapsular hepatic hematoma is an infrequent and severe complication of hypertension in pregnancy and should be suspected when there are clinical signs compatible with this diagnosis, which should be confirmed by abdominal computed tomography. Prompt diagnosis and treatment are important to avoid rupture, thus improving the high associated maternal and fetal morbidity and mortality.

A silicon-tungsten sampling imaging calorimeter has been designed and built for thePAMELA satellite-borne experiment. The main physics goals of the experiment are themeasurement of the flux of anti ...

A sampling silicon‐tungsten imaging calorimeter has been designed and built for the PAMELA satellite‐borne experiment. The calorimeter has been designed to identify antiprotons from an electron background and positrons in a background of protons with a high efficiency and rejection power. In this work we present the identification capabilities of the calorimeter obtained using both Monte Carlo and test beam data. We show that the calorimeter provides a proton rejection factor of at least 105 while keeping a high efficiency in selecting electrons and positrons. Hence, the calorimeter will fulfill the identification power needed to reach the primary scientific objectives of PAMELA, that are the measurement of the flux of antiprotons, positrons and light isotopes in the cosmic radiation.

Collaboration of various specialists has become essential in pediatric dental practice. In orthodontics, this collaboration is completely necessary when the patient presents periodontal problems. Even in healthy patients, who do not suffer from periodontal disease, periodontal complications may occur during treatment with fixed appliances. Two cases of young patients, in which periodontal procedures were used to complement the results of orthodontic treatment are presented.