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2. 1H NMR study of the complexation of aromatic drugs with dimethylxanthine derivatives

Author

A. A. Hernandez Santiago, R. Gutiérrez Pérez, D.V. Ovchinnikov, S. Rosas Castilla, Maxim P. Evstigneev, H. G. Parkes, M. Gonzalez Flores, A. M. Cervantes Tavera, and V.V. Khomich

Subjects
Inorganic Chemistry, chemistry.chemical_compound, chemistry, Stereochemistry, Organic Chemistry, Proton NMR, Molecule, Nuclear magnetic resonance spectroscopy, Caffeine, Ethidium bromide, Spectroscopy, Proflavine, Analytical Chemistry
Abstract

With an aim of searching efficient interceptors of aromatic drugs, the self- and hetero-association of dimethylxanthine derivatives with different structures, selected according to Strategy 1 (variation of the position of methyl groups) and Strategy 2 (variation of the length of -(CH2)(n)-COOH group), with aromatic drug molecules: Ethidium Bromide, Proflavine and Daunomycin, were studied using H-1 NMR spectroscopy. It was found that the association proceeds in a form of stacking-type complexation and its energetics is relatively independent on the structure of the dimethylxanthines. However, on average, the dimethylxanthines possess higher hetero-association constant and, hence, higher interceptor ability as compared to the trimethylxanthine, Caffeine, used during the past two decades as a typical interceptor molecule. (C) 2011 Elsevier B.V. All rights reserved.

Published
2012

3. Efecto de la temperatura y concentración de glucosa en la síntesis verde de nanopartículas de plata

Author

R . García Hernández, R. Agustín Serrano, A. A. Hernandez Santiago, M. A. Morales Sánchez, A. M. Cervantes Tavera, and H. Flores Méndez

Abstract

Las nanopartículas de plata pueden ser usadas para aplicaciones antifungicidas y también para mejorar la resolución de los espectros Raman. Es este artículo es reportada la síntesis de nanopartículas de Ag empleando un buen agente reductor (glucosa). La glucosa es usada debido a que no contamina el medio ambiente. Las nanopartículas fueron caracterizadas por espectroscopia IR (Infrarroja) y UV-Vis (ultravioleta-visible), también para la determinación del tamaño y composición se empleo EDS (análisis elemental por espectroscopia de rayos X de energía dispersiva) y SEM (microscopia electrónica de barrido). Durante la síntesis fue cambiada la temperatura y la relación de glucosa, el resultado es la obtención de nanopartículas de 78.7 nm de diámetro (diámetro promedio).

Published
2018

4. Windkessel Model in the Qualitative Analysis of the Circulatory System of Smokers

Author

M. M. Tavera, Sandra Wray, J. F. Remolina, Leandro J. Cymberknop, and Ricardo L. Armentano

Subjects
medicine.medical_specialty, Cardiac output, Smoking habit, business.industry, Windkessel model, Arterial impedance, Compliance (physiology), Qualitative analysis, Blood pressure, Internal medicine, Circulatory system, medicine, Cardiology, business
Abstract

Introduction: A computer model was developed to estimate the arterial pressure and the cardiac output of humans, by adapting the equations of the Windkessel theory. Material and Methods: The model inputs are based on certain characteristics of patients, such as age, the use of specific drugs and smoking habits. It also predicts the effect of smoking on any of the constituent variables of arterial impedance (Compliance and Resistance) and establishes a statistically significant relationship between them. Results: The outputs of the model are strongly correlated with physiological observations, with a minimum error of 3% for the arterial pressure. Conclusion: The proposed model is useful for providing an easy and low cost estimation of arterial pressure.

Published
2015

5. [Arrhythmias in adult patients with congenital heart disease]

Author

S, Foresti, M C, Tavera, P P, Lupo, and R, Cappato

Subjects
Adult, Heart Defects, Congenital, Heart Diseases, Humans, Arrhythmias, Cardiac
Abstract

Arrhythmias are the main cause of morbidity and mortality in adult patients with congenital heart disease. Arrhythmias can be due to the primary anatomical defect or they can be a consequence of the long term effects of haemodynamical defects and surgical repairs. Atrial arrhythmias are the most frequent form and their prevalence varies between 10-60% in different congenital defects. Ventricular tachycardia are less common but they have potentially a dramatic impact on survival. When correcting the haemodynamic defect is not effective in avoiding arrhythmias complications, it is necessary to apply specific therapy. Antiarrhythmic drugs must be used very carefully, there is an increasing application for transcatheter or surgical ablation and device implantation.

Published
2011

6. Counseling and informed consent: the experience in a pediatric cardiology unit. How to communicate a pathological diagnosis

Author

S, Montis, P P, Bassareo, C, Follese, P, Neroni, M C, Tavera, and R, Tumbarello

Subjects
Counseling, Male, Parents, Informed Consent, Heart Diseases, Pregnancy, Communication, Surveys and Questionnaires, Diagnosis, Humans, Social Support, Female, Hospital Units
Abstract

The aim of our study was to create an operative scheme for conveying a pathological diagnosis with emphasis on communication strategies. In order to check the validity of the scheme, parents of 122 of our patients were contacted by an outside observer and were asked to answer anonymously to a questionnaire concerning their experience in our unit. The questionnaire has been structured in three parts in order to verify (1) the quality of the communication of the diagnosis, (2) the team-patient relationship and (3) the comparison between our unit and the others. 87% of parents declared the language used in the communication clear and comprehensible and the time dedicated to the explanations sufficient (p.01). They judged the quality of the information received as excellent (50%) or good (50%) (p.01). Eightyfour % of them thought that the information given was sufficient and there was no need for any more details (p.01). 92% perceived a comfortable atmosphere, they felt involved in the communication and encouraged to ask questions (p.01). 91% described the behaviour of the team as helpful and warm without differences between the different figures of the unit (p.01). In regard to the psychological support 70% of parents found it essential, 30% found it very useful (p.05). These results show that our operative scheme is functional to the communication and to the team-patient relationship. It permits an "informed consent" as an aware choice of the parents and consequently a better way of management of the congenital heart disease.

Published
2010

7. Supraventricular tachycardia in neonates: antiarrhythmic drug choice dilemma

Author

M C, Tavera, P P, Bassareo, P, Neroni, C, Follese, D, Manca, S, Montis, and R, Tumbarello

Subjects
Dose-Response Relationship, Drug, Decision Making, Infant, Newborn, Tachycardia, Supraventricular, Humans, Anti-Arrhythmia Agents, Chemoprevention, Choice Behavior, Risk Assessment
Abstract

Supraventricular tachycardia (SVT), being atrioventricular reentry the underlying mechanism, is the most frequently tachyarrhythmia requiring a medical treatment in infants with no cardiac disease. The acute treatment of a single episode of SVT has generally an excellent prognosis. An antiarrhythmic prophylaxis of SVT recurrences is usually recommended during the first year of life. Although many efficient drugs are available for the SVT treatment, a careful risk-benefit analysis of each single case should suggest the correct drug choice.

Published
2010

8. Sudden stratospheric warmings seen in MINOS deep underground muon data

Author

S. J. Coleman, Caleb Smith, J. M. Paley, R. P. Litchfield, A. Holin, A. A. Wehmann, P. Vahle, S. Cavanaugh, P. A. Symes, A. Sousa, P. J. Litchfield, David Petyt, D. J. Boehnlein, D. J. Auty, N. Mayer, S. Kumaratunga, J. Urheim, R. Hatcher, M. V. Diwan, Warner A. Miller, V. Paolone, C. R. Bower, J. J. Kim, D. G. Michael, N. Tagg, A. Himmel, Brajesh C Choudhary, L. Mualem, G.D. Barr, N. West, Alec Habig, P. Lucas, J. Smith, B. Baller, D. S. Ayres, G. Koizumi, Harvey B Newman, J. L. Thron, J. A. Musser, Richard J.H. Smith, J. J. Evans, T. M. Raufer, Z. Pavlovic, K. E. Arms, John Derek Chapman, D. Bogert, B. Speakman, D. Cherdack, Scott Osprey, Gregory J Pawloski, Jorge G. Morfin, G. M. Irwin, J. H. Cobb, S. R. Mishra, N. Grossman, K. Grzelak, C. J. Metelko, J. R. Meier, Jian Ma, M. A. Thomson, D. Naples, M. Kordosky, A. Godley, W. Smart, M. Dierckxsens, J. Reichenbacher, Juergen Thomas, S. Childress, G. J. Feldman, R. Ospanov, C. Andreopoulos, Sacha E Kopp, R. Gran, John Marshall, L. Loiacono, Stanley G. Wojcicki, C. James, T. Yang, P. Gouffon, B. R. Becker, D. J. Koskinen, L. Miller, Andrew Blake, J. Boehm, R. C. Webb, J. Hylen, R. H. Bernstein, P. A. Rodrigues, J. A. Thompson, J. K. De Jong, E. Grashorn, M. Ishitsuka, M. C. Sanchez, S. M. Seun, Carlos Escobar, M. Watabe, A. Belias, R. J. Nichol, M. Dorman, B. Viren, R. K. Plunkett, M. C. Goodman, D. E. Jaffe, H. R. Gallagher, C. D. Moore, J. K. Nelson, Peter D. Barnes, Niki Saoulidou, A. M. McGowan, H. A. Rubin, D. A. Harris, K. Ruddick, T. Kafka, Matthew L Strait, G. F. Pearce, D. A. Jensen, William L. Barrett, P. Shanahan, P. Stamoulis, M. D. Messier, R. L. Talaga, P. Schreiner, Christopher G. White, C. W. Peck, K. Zhang, J. Schneps, W. A. Mann, M. V. Frohne, Karol Lang, M. Bishai, Juan Pedro Ochoa-Ricoux, S. A. Dytman, R. Armstrong, W. P. Oliver, Philip Harris, Douglas Wright, A. E. Kreymer, Marvin L Marshak, A. C. Weber, G. Tzanakos, D. Bhattacharya, R. Pittam, J. Hartnell, M. A. Tavera, G. Tinti, John J. Barnett, T. C. Nicholls, S. L. Mufson, G. J. Bock, S. M S Kasahara, B. Rebel, A. Rahaman, R. Zwaska, A. J. Culling, C. Rosenfeld, P. Adamson, R. A. Rameika, E. Buckley-Geer, and E. Falk

Subjects
Physics, Muon, Physics::Instrumentation and Detectors, Cosmic ray muons, Cosmic ray, Atmospheric sciences, Atmospheric temperature, Troposphere, Atmosphere, Geophysics, MINOS, Climatology, General Earth and Planetary Sciences, High Energy Physics::Experiment, Stratosphere, Physics::Atmospheric and Oceanic Physics
Abstract

The rate of high energy cosmic ray muons as measured underground is shown to be strongly correlated with upper-air temperatures during short-term atmospheric (10-day) events. The effects are seen by correlating data from the MINOS underground detector and temperatures from the European Centre for Medium Range Weather Forecasts during the winter periods from 2003-2007. This effect provides an independent technique for the measurement of meteorological conditions and presents a unique opportunity to measure both short and long-term changes in this important part of the atmosphere. Copyright 2009 by the American Geophysical Union.

Published
2009

9. Search for Active Neutrino Disappearance Using Neutral-Current Interactions in the MINOS Long-Baseline Experiment

Author

P. Adamson, C. Andreopoulos, K. E. Arms, R. Armstrong, D. J. Auty, D. S. Ayres, C. Backhouse, B. Baller, G. Barr, W. L. Barrett, B. R. Becker, A. Belias, R. H. Bernstein, D. Bhattacharya, M. Bishai, A. Blake, G. J. Bock, J. Boehm, D. J. Boehnlein, D. Bogert, C. Bower, E. Buckley-Geer, S. Cavanaugh, J. D. Chapman, D. Cherdack, S. Childress, B. C. Choudhary, J. H. Cobb, S. J. Coleman, A. J. Culling, J. K. de Jong, M. Dierckxsens, M. V. Diwan, M. Dorman, S. A. Dytman, C. O. Escobar, J. J. Evans, E. Falk Harris, G. J. Feldman, M. V. Frohne, H. R. Gallagher, A. Godley, M. C. Goodman, P. Gouffon, R. Gran, E. W. Grashorn, N. Grossman, K. Grzelak, A. Habig, D. Harris, P. G. Harris, J. Hartnell, R. Hatcher, K. Heller, A. Himmel, A. Holin, L. Hsu, J. Hylen, G. M. Irwin, M. Ishitsuka, D. E. Jaffe, C. James, D. Jensen, T. Kafka, S. M. S. Kasahara, J. J. Kim, M. S. Kim, G. Koizumi, S. Kopp, M. Kordosky, D. J. Koskinen, S. K. Kotelnikov, A. Kreymer, S. Kumaratunga, K. Lang, J. Ling, P. J. Litchfield, R. P. Litchfield, L. Loiacono, P. Lucas, J. Ma, W. A. Mann, A. Marchionni, M. L. Marshak, J. S. Marshall, N. Mayer, A. M. McGowan, J. R. Meier, M. D. Messier, C. J. Metelko, D. G. Michael, W. H. Miller, S. R. Mishra, C. D. Moore, J. Morfín, L. Mualem, S. Mufson, S. Murgia, J. Musser, D. Naples, J. K. Nelson, H. B. Newman, R. J. Nichol, T. C. Nicholls, J. P. Ochoa-Ricoux, W. P. Oliver, R. Ospanov, J. Paley, V. Paolone, A. Para, T. Patzak, Ž. Pavlović, G. Pawloski, G. F. Pearce, C. W. Peck, D. A. Petyt, R. Pittam, R. K. Plunkett, A. Rahaman, R. A. Rameika, T. M. Raufer, B. Rebel, J. Reichenbacher, P. A. Rodrigues, C. Rosenfeld, H. A. Rubin, V. A. Ryabov, M. C. Sanchez, N. Saoulidou, J. Schneps, P. Schreiner, P. Shanahan, W. Smart, C. Smith, A. Sousa, B. Speakman, P. Stamoulis, M. Strait, N. Tagg, R. L. Talaga, M. A. Tavera, J. Thomas, M. A. Thomson, J. L. Thron, G. Tinti, I. Trostin, V. A. Tsarev, G. Tzanakos, J. Urheim, P. Vahle, B. Viren, D. R. Ward, M. Watabe, A. Weber, R. C. Webb, A. Wehmann, N. West, C. White, S. G. Wojcicki, D. M. Wright, T. Yang, K. Zhang, R. Zwaska, APC - Neutrinos, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), MINOS, AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Physics, Particle physics, etc, Neutrino mass and mixing, [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Neutral current, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, FOS: Physical sciences, General Physics and Astronomy, right-handed neutrinos, 01 natural sciences, High Energy Physics - Experiment, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], High Energy Physics - Experiment (hep-ex), Neutral currents, MINOS, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], High Energy Physics::Experiment, Neutrino, 010306 general physics, Baseline (configuration management), Non-standard-model neutrinos
Abstract

We report the first detailed comparisons of the rates and spectra of neutral-current neutrino interactions at two widely separated locations. A depletion in the rate at the far site would indicate mixing between muon neutirnos and a sterile particle. No anomalous depletion in the reconstructed energy spectrum is observed. Assuming oscillations occur at a single mass-squared splitting, a fit to the neutral- and charged-current energy spectra limits the fraction of muon neutrino oscillating to a sterile neutrino to be below 0.68 at 90% confidence level. A less stringent limit due to a possible contribution to the measured neutral-current event rate at the far site from electron neutrino appearance at the current experimental limit is also presented., Comment: 5 pages, 3 figures

Published
2008

10. Measurement of Neutrino Oscillations with the MINOS Detectors in the NuMI Beam

Author

Jian Ma, M. A. Thomson, D. Naples, Stanley G. Wojcicki, J. Hylen, R. H. Bernstein, A. Para, M. C. Goodman, P. A. Symes, S. K. Kotelnikov, V. A. Ryabov, J. Schneps, S. A. Dytman, M. V. Diwan, Gregory J Pawloski, Jorge G. Morfin, R. A. Rameika, C. James, A. Holin, N. Tagg, R. Pittam, G.D. Barr, G. M. Irwin, K. E. Arms, R. P. Litchfield, M. Kordosky, A. Godley, John Marshall, Sacha E Kopp, R. Gran, G. J. Feldman, Andrew Blake, A. Sousa, C. P. Ward, P. J. Litchfield, Philippe Lucas, John Miller, Brajesh C Choudhary, Juergen Thomas, Peter D. Barnes, S. Murgia, M. Bishai, D. J. Auty, B. Baller, M. D. Messier, G. I. Merzon, W. Smart, Warner A. Miller, N. West, G. Tinti, P. Vahle, Harvey B Newman, J. L. Thron, H. A. Rubin, D. S. Ayres, S. Cavanaugh, P. Adamson, D. J. Boehnlein, J. J. Evans, M. Dierckxsens, R. Armstrong, D. R. Ward, T. Patzak, A. C. Weber, W. P. Oliver, P. Stamoulis, A. Rahaman, T. C. Nicholls, G. J. Bock, J. K. de Jong, A. E. Kreymer, B. Speakman, E. A. Peterson, S. M S Kasahara, R. Ospanov, Marvin L Marshak, S. J. Coleman, S. M. Seun, M. Dorman, M. Ishitsuka, Caleb Smith, A. M. McGowan, K. Ruddick, Niki Saoulidou, B. Rebel, G. F. Pearce, J. Boehm, Ken Heller, J. M. Paley, S. Kumaratunga, E. Buckley-Geer, P. Gouffon, B. R. Becker, A. A. Wehmann, P. A. Rodrigues, M. A. Tavera, M. Watabe, William L. Barrett, P. Shanahan, M. C. Sanchez, R. C. Webb, J. A. Thompson, C. Rosenfeld, R. Zwaska, A. J. Culling, Douglas Wright, D. Bogert, T. Kafka, W. A. Mann, D. Cherdack, B. Viren, A. Marchionni, J. K. Nelson, I. Trostin, Philip Harris, C. Andreopoulos, D. A. Jensen, M. S. Kim, R. L. Talaga, S. L. Mufson, L. Loiacono, J. J. Kim, D. E. Jaffe, V. A. Tsarev, David Petyt, A. Belias, Matthew L Strait, J. H. Cobb, T. M. Raufer, S. R. Mishra, N. Grossman, Ž Pavlović, Juan Pedro Ochoa-Ricoux, Carlos Escobar, R. K. Plunkett, E. Grashorn, K. Grzelak, P. Schreiner, John Derek Chapman, R. J. Nichol, C. J. Metelko, J. R. Meier, Alec Habig, J. Urheim, V. Paolone, C. R. Bower, S. Childress, R. Hatcher, E. Falk Harris, C. D. Moore, J. A. Musser, C. White, M. V. Frohne, T. Yang, A. Himmel, L. Mualem, D. G. Michael, M. Zois, N. Mayer, C. W. Peck, G. Tzanakos, K. Zhang, G. Koizumi, Karol Lang, J. Reichenbacher, D. J. Koskinen, H. R. Gallagher, D. A. Harris, D. Bhattacharya, J. Hartnell, APC - Neutrinos, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), MINOS, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), and Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Particle physics, Neutrino mass and mixing, [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Physics::Instrumentation and Detectors, Solar neutrino, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, General Physics and Astronomy, 01 natural sciences, NuMI, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Ordinary neutrinos (nuW bosons, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 010306 general physics, Neutrino oscillation, Physics, 010308 nuclear & particles physics, Beams in particle accelerators, High Energy Physics::Phenomenology, Solar neutrino problem, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Spectrometers and spectroscopic techniques, Neutrino detector, MINOS, Measurements of neutrino speed, High Energy Physics::Experiment, Neutrino
Abstract

This letter reports new results from the MINOS experiment based on a two-year exposure to muon neutrinos from the Fermilab NuMI beam. Our data are consistent with quantum mechanical oscillations of neutrino flavor with mass splitting $|\Delta m^2|=(2.43\pm 0.13)\times10^{-3}$ eV$^2$ (68% confidence level) and mixing angle $\sin^2(2\theta)>0.90$ (90% confidence level). Our data disfavor two alternative explanations for the disappearance of neutrinos in flight, namely neutrino decays into lighter particles and quantum decoherence of neutrinos, at the 3.7 and 5.7 standard deviation levels, respectively., Comment: 5 pages, 4 figures, submitted to Phys. Rev. Lett

Published
2008

11. Complexation of biologically active aromatic compounds with DNA in the presence of theophylline

Author

A. M. Cervantes Tavera, David B. Davies, A. A. Hernandez Santiago, Maxim P. Evstigneev, and D.D. Andrejuk

Subjects
Original Paper, Stereochemistry, Ligand, Oligonucleotide, Biophysics, Biological activity, hemic and immune systems, Cell Biology, Combinatorial chemistry, Atomic and Molecular Physics, and Optics, chemistry.chemical_compound, chemistry, medicine, Proton NMR, Theophylline, lipids (amino acids, peptides, and proteins), Ethidium bromide, Molecular Biology, Proflavine, DNA, medicine.drug
Abstract

(1)H NMR measurements (500 MHz) have been used to determine the equilibrium hetero-association constants of theophylline (THP) with various biologically active aromatic compounds (daunomycin, novantrone, ethidium bromide, proflavine, norfloxacin) and the complexation constants of THP with both single- and double-stranded oligonucleotides in solution. The results provide a quantitative estimation of the effect of THP on the binding of aromatic ligands with DNA, and a determination of the fraction of aromatic ligand removed from DNA on addition of THP.

Published
2008

12. Testing Lorentz Invariance and CPT Conservation with NuMI Neutrinos in the MINOS Near Detector

Author

K. Grzelak, A. Belias, T. C. Nicholls, A. E. Kreymer, E. Grashorn, Marvin L Marshak, C. Rosenfeld, P. Adamson, K. E. Arms, P. Schreiner, G. M. Irwin, D. E. Jaffe, John Marshall, A. C. Weber, Sacha E Kopp, R. Gran, R. Zwaska, A. J. Culling, S. L. Mufson, A. Rahaman, J. Urheim, G. J. Feldman, Ken Heller, V. Paolone, C. R. Bower, W. Smart, R. Ospanov, P. Lucas, D. Bogert, S. M S Kasahara, M. A. Tavera, M. Zois, A. Sousa, J. Schneps, A. M. McGowan, D. G. Michael, B. Rebel, J. A. Musser, J. K. De Jong, H. A. Rubin, N. Grossman, M. Ishitsuka, P. J. Litchfield, John Derek Chapman, A. Holin, S. A. Dytman, M. D. Messier, S. Childress, P. Vahle, M. Kordosky, Carlos Escobar, S. Cavanaugh, P. Gouffon, S. Murgia, Jian Ma, M. A. Thomson, C. J. Metelko, Christopher G. White, R. J. Nichol, R. C. Webb, J. R. Meier, J. A. Thompson, Andrew Blake, R. K. Plunkett, D. Naples, R. Armstrong, D. J. Boehnlein, E. Falk Harris, M. Bishai, B. Baller, C. D. Moore, Stanley G. Wojcicki, W. P. Oliver, S. Kumaratunga, Alec Habig, D. J. Auty, Philip Harris, H. R. Gallagher, N. West, M. V. Frohne, J. Hylen, R. H. Bernstein, A. Para, T. Yang, M. C. Goodman, D. A. Harris, Matthew L Strait, M. V. Diwan, A. Himmel, C. W. Peck, L. Mualem, D. S. Ayres, K. Zhang, J. Boehm, R. Pittam, P. Stamoulis, D. Bhattacharya, J. J. Evans, J. Hartnell, J. K. Nelson, D. Cherdack, T. Patzak, Karol Lang, Ž Pavlović, Warner A. Miller, N. Mayer, Juan Pedro Ochoa-Ricoux, R. Hatcher, B. Speakman, G. Tinti, William L. Barrett, D. A. Jensen, P. Shanahan, G. J. Bock, C. Andreopoulos, D. J. Koskinen, L. Loiacono, W. A. Mann, P. A. Rodrigues, M. Watabe, G. Tzanakos, T. Kafka, G. Koizumi, J. Reichenbacher, J. J. Kim, E. Buckley-Geer, R. A. Rameika, M. Dorman, Niki Saoulidou, G. F. Pearce, B. R. Becker, R. P. Litchfield, M. C. Sanchez, Brajesh C Choudhary, Gregory J Pawloski, Jorge G. Morfin, C. James, David Petyt, T. M. Raufer, S. R. Mishra, S. J. Coleman, J. M. Paley, A. A. Wehmann, N. Tagg, G.D. Barr, John Miller, Juergen Thomas, Harvey B Newman, J. L. Thron, B. Viren, R. L. Talaga, APC - Neutrinos, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), MINOS, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Particle physics, Neutrino mass and mixing, [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], CPT symmetry, Physics::Instrumentation and Detectors, Lorentz transformation, time reversal, Charge conjugation, General Physics and Astronomy, FOS: Physical sciences, Lorentz covariance, Lorentz and Poincare invariance, 01 natural sciences, NuMI, High Energy Physics - Experiment, symbols.namesake, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], 010306 general physics, Neutrino oscillation, and other discrete symmetries, Physics, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], High Energy Physics - Phenomenology, MINOS, parity, symbols, Measurements of neutrino speed, High Energy Physics::Experiment, Neutrino
Abstract

A search for a sidereal modulation in the MINOS near detector neutrino data was performed. If present, this signature could be a consequence of Lorentz and CPT violation as predicted by the effective field theory called the standard-model extension. No evidence for a sidereal signal in the data set was found, implying that there is no significant change in neutrino propagation that depends on the direction of the neutrino beam in a sun-centered inertial frame. Upper limits on the magnitudes of the Lorentz and CPT violating terms in the standard-model extension lie between 10-4 and 10-2 of the maximum expected, assuming a suppression of these signatures by a factor of 10-17. © 2008 The American Physical Society.

Published
2008
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13. Síntesis y caracterización de nanopartículas de Fe203 dopadas con plata con propiedades f otoactivas

Author

A. M. Cervantes Tavera, A. A. Hernández Santiago, H. Flores Méndez, M.A. Morales Sánchez, R. Agustin Serrano, and R. García Hernández

Abstract

En este trabajo de investigación se sintetizaron y caracterizaron nanopartículas de Fe2Ü3 con la finalidad de obtener unadisminución en el valor para su banda prohibida. Fue empleada una solución de AgNO3 para dopar el material, y se encontró que al cambiar el valor de la concentración de esta disolución durante el proceso de síntesis disminuye el valor de la banda prohibida. El rango de variación de la banda prohibida de las nanopartículas disminuye en un rango de 2.91 a 1.73 eV al mezclarlas con la disolución de AgNO3. La caracterización fue realizada mediante las técnicas de IR, RAMAN, Uv-Vis, EDS, SEM y DRX. El tamaño de las nanopartículas obtenidas fueron de 80 nm de diámetro aproximadamente. Para estimar el valor de la banda prohibida fue empleada la relación de Kubelka-Munk, así como la ley de Bragg para estimar el tamaño de partícula. Las nanopartículas obtenidas tienen un valor para la banda prohibida y un tamaño de partícula apropiado para ser empleado en la elaboración de celdas solares.

Published
2015

14. Patrones de cierre velofaringeo: Estudio comparativo entre población sana y pacientes con paladar hendido.

Author

Madrid, J. R. Prada, Venegas, T. García, Brando, M. P. Echeverri, and Herrera, M. C. Tavera

Abstract

Copyright of Cirugía Plástica Ibero-Latinoamericana is the property of Cirugia Plastica Ibero-Latinoamericana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2010
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15. An APL system for the IBM Personal Computer

Author

J. Rojas, M. L. Tavera, and Manuel Alfonseca

Subjects
General Computer Science, Assembly language, Programming language, Computer science, Character encoding, computer.software_genre, Computer Graphics and Computer-Aided Design, Theoretical Computer Science, Computational Theory and Mathematics, IBM PC compatible, Personal computer, Session (computer science), Compiler, IBM, computer, Software, Interpreter, Information Systems, computer.programming_language
Abstract

This paper discusses the design and building of an APL interpreter for the IBM Personal Computer. Discussed is the writing of the interpreter itself, which required the use of an intermediate language designed by the authors. This machine-independent language also made possible the development of APL interpreters for two other systems--System/370 and Series/1. The particularizing of the interpreter required a compiler, which in the case of the Personal Computer produced Intel 8088 and 8087 assembly language code. The matching of the APL interpreter to the operating system (DOS) required an APL supervisor, which is also discussed in this paper. The provision of the APL character set presented problems, the solutions of which are also presented. Other topics discussed are the display, the keyboard, and the session manager.

Published
1985

16. An APL interpreter and system for a small computer

Author

R. Casajuana, Manuel Alfonseca, and M. L. Tavera

Subjects
Computational Theory and Mathematics, General Computer Science, Programming language, Computer science, Control (management), Emphasis (telecommunications), computer.software_genre, Computer Graphics and Computer-Aided Design, computer, Software, Interpreter, Information Systems, Theoretical Computer Science
Abstract

The design and implementation of an experimental APL system on the small, sensor-based System/7 is described. Emphasis is placed on the solution to the problem of fitting a full APL system into a small computer. The system has been extended through an I/O auxiliary processor to make it possible to use APL in the management and control of the System/7 sensor-based I/O operations.

Published
1977

17. A Machine-Independent APL Interpreter

Author

Manuel Alfonseca, M. L. Tavera, and UAM. Departamento de Ingeniería Informática

Subjects
Compilers and interpreters, Informática, General Computer Science, Computer science, Programming language, computer.software_genre, Intermediate level, Data structures and accessing, Mathematics (applied), System programming, Programming, Compiler, Compiled language, computer, Interpreter
Abstract

Available in IEEE Xplore digital library., The problem of writing machine-independent APL interpreters is solved by means of a systems programming approach making use of an intermediate level language specially designed for that purpose. This paper describes the language, as well as the procedure used to build universal interpreters. Three compilers that translate this language for three different machines have been written so far, and an APL interpreter has been finished

Published
1978

18. The IBM personal computer APL system

Author

Manuel Alfonseca, M. L. Tavera, and J. Rojas

Subjects
Computer science, business.industry, Process (computing), Time-sharing, General Medicine, computer.software_genre, Minicomputer, Multiple sensors, law.invention, Software, Human–computer interaction, law, Personal computer, Operating system, Program development, IBM, business, computer
Abstract

In 1973, we decided to enhance the software of our System/7 computer with one interactive time sharing system, and chose APL as the target language. System/7 is a sixteen bit minicomputer embodying a disk unit and multiple sensor based facilities, including analog and digital input/output as well as process interrupts. It was our purpose to support all those facilities within our system, in such a way that APL could become the main program development language for those projects in the Scientific Center using this minicomputer.

Published
1984

19. 'Extension of APL to tree-structured information'

Author

Manuel Alfonseca and M. L. Tavera

Subjects
Set (abstract data type), Tree (data structure), Disk formatting, Theoretical computer science, Computer science, Programming language, Systems management, Point (geometry), Minification, Coherence (philosophical gambling strategy), Extension (predicate logic), computer.software_genre, computer
Abstract

A new outlook on the APL system management together with a new set of primitive functions are proposed to be included in the APL language to manage tree-structured information.Since the appearance of APL, this language has been prone to extension requirements, possibly due to the fact that it allows such an ease of computing and programming, that the user quickly arrives to the point where he should like to have something else to make even more complex procedures with even less programming effort. Some of such requirements have been accepted and are now operative, namely the execute and formatting functions and the scan operator.Our approach has selected the planar tree as a new APL object.Stress has been applied to the minimization of the number of primitive functions and symbols extensions needed to handle the new objects as well as the maintaining of a maximum coherence between our extensions and the standard APL operations. In addition to this, a new work space library organization is proposed in order to overcome the limitations inherent to the present limited work space size and file management.

Published
1976

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