527 results on '"M. A. Riley"'
Search Results
2. Effects of a Concurrent Memory Task on the Maintenance of Upright Stance
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V. C. Ramenzoni and M. A. Riley
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- 2023
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3. Fifty Years of Backbending
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R. Wyss and M. A. Riley
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Nuclear and High Energy Physics - Published
- 2022
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4. An Interactive Final Exam Review
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Genevieve B. Elrod and Kellie M. J. Riley
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Review and Exam Preparation ,Fundamentals and skills ,LPN and LVN ,Education - Published
- 2023
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5. Stanford Interdisciplinary Working Group on Interoperability: Report and Preliminary Recommendations
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Mark A. Lemley, Eric E. Johnson, and M. Christopher Riley
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History ,Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2023
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6. SHORTNESS OF BREATH IN THE SETTING OF ATRIAL FIBRILLATION: CHICKEN BEFORE THE EGG?
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EKANAYAKE, LAKMAL S, primary, M PICKETT, RILEY, additional, and S CHATTERJEE, ROHINI, additional
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- 2022
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7. A novel approach for detection of damage in adhesively bonded joints in plastic pipes based on vibration method using piezoelectric sensors.
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N. Cheraghi, M. J. Riley, and F. Taheri
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- 2005
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8. Anarchy, State, or Utopia?: Checks and Balances in Internet Governance.
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M. Christopher Riley
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- 2013
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9. Control of three gastrointestinal illness outbreaks in a British Role 1 facility in Afghanistan: a primary care perspective
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R Robinson, M R Riley, L Hudson, Seth Makin, and D Murphy
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0301 basic medicine ,medicine.medical_specialty ,Isolation (health care) ,media_common.quotation_subject ,030106 microbiology ,Population ,Disease Outbreaks ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Hygiene ,law ,Environmental health ,Epidemiology ,Quarantine ,medicine ,Humans ,030212 general & internal medicine ,education ,Caliciviridae Infections ,media_common ,education.field_of_study ,Primary Health Care ,business.industry ,Public health ,Incidence (epidemiology) ,Norovirus ,Afghanistan ,Outbreak ,General Medicine ,Gastroenteritis ,business - Abstract
IntroductionIn 2019, Camp Qargha (QAA), a British-led multinational military camp in Kabul, had three of the largest outbreaks of gastrointestinal illness (GI) experienced by the British Military since 2003. This paper discusses the incidence, the response of the British-led Role 1 (R1) medical treatment facility, identifies potential causative and exacerbating factors, and explains the control measures initiated.MethodGI in QAA results in local and UK military-wide data collection including in the form of local GI questionnaires, FMed85 forms and EpiNATO returns. The data from these was used to identify trends during and after outbreaks and produce environmental health (EH) and local outbreak reports.ResultsOverall, among the outbreaks 56% of stool samples tested positive for norovirus. In each outbreak incidence peaked within the first 3 days, and hardened multiperson rooms were worst affected. 206 patient presentations occurred during the three outbreaks, 706 working days were lost in isolation, with QAA shut down while in quarantine for 27 days.DiscussionSignificant strain was placed on QAA and the R1. Causative factors may include close interaction with the local national (LN) population, a high population density and accommodation being limited by specific national infrastructure protocols in an operational environment.ConclusionEarly recognition of GI, positive standard operating procedures and good hygiene habits are essential to prevent the spread of GI such as norovirus. An early awareness of LN population illness patterns will allow the R1 and command to be better prepared for outbreaks in the future.
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- 2020
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10. νi13/2 structures in Sm155 and Gd159 : Supporting evidence of a Z=60 deformed subshell gap
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D. J. Hartley, F. G. Kondev, M. P. Carpenter, R. V. F. Janssens, M. A. Riley, K. Villafana, K. Auranen, A. D. Ayangeakaa, J. S. Baron, A. J. Boston, J. A. Clark, J. P. Greene, J. Heery, C. R. Hoffman, T. Lauritsen, J. Li, D. Little, E. S. Paul, G. Savard, D. Seweryniak, J. Simpson, S. Stolze, G. L. Wilson, J. Wu, and S. Zhu
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- 2022
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11. PEDANT genome database: 10 years online.
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M. Louise Riley, Thorsten Schmidt, Irena I. Artamonova, Christian Wagner 0008, Andreas Volz, Klaus Heumann, Hans-Werner Mewes, and Dmitrij Frishman
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- 2007
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12. The Mouse Functional Genome Database (MfunGD): functional annotation of proteins in the light of their cellular context.
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Andreas Ruepp, Octave Noubibou Doudieu, Jos van den Oever, Barbara Brauner, Irmtraud Dunger-Kaltenbach, Gisela Fobo, Goar Frishman, Corinna Montrone, Christine Skornia, Steffi Wanka, Thomas Rattei, Philipp Pagel, M. Louise Riley, Dmitrij Frishman, Dimitrij Surmeli, Igor V. Tetko, Matthias Oesterheld, Volker Stümpflen, and Hans-Werner Mewes
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- 2006
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13. The PEDANT genome database in 2005.
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M. Louise Riley, Thorsten Schmidt, Christian Wagner 0008, Hans-Werner Mewes, and Dmitrij Frishman
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- 2005
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14. Harnessing Change: Human Health through the Lense of Evolution and Dynamical Systems Theory
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Maher, M. Cyrus Riley
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Genetics ,Statistics ,Computer science ,Dynamical systems ,Evolution ,Evolutionary medicine ,Open source software ,Personalized medicine - Abstract
Over 2000 years ago, Heraclitus noted, "Everything changes and nothing stands still ." While this truth has long been evident to the wise, we have only recently developed the tools necessary to scientifically characterize sweeping patterns of change in large dynamical systems. Despite rapid progress, new methods and data sources are still sorely needed to further illuminate the intricate and dynamic nature of reality. In this dissertation, we will focus our investigations on understanding patterns of change with direct relevance to human health. In the first two chapters, we develop novel methodologies that lend insight into the evolutionary history of the human race and the genetic basis of human-specific traits and disease. Chapter 2 presents MOSAIC, a new python package for improved detection of genetically related genes between species. This inference is a foundational step towards understanding the function of proteins and the evolutionary pressures they have faced. This tool, along with a combination of other methods, facilitates our analysis in Chapter 3. In this section, we use the patterns of mutations along the human lineage to discover genes and even specific mutations that may play important roles in intelligence, obesity, mental health, as well as a variety of basic biological functions. These findings provide insight into the genetic architecture of health and disease. At the same time, they leave open questions about how genetic factors interact with the broad array of environmental and ecological variables that fundamentally shape downstream phenotypes. In Chapter 4, we introduce CauseMap, a tool I built to understand causal relationships within complex dynamical systems using time series data. It is our hope that this method will help us to interpret human health and disease as states of the bodily dynamical system embedded inextricably within an evolving social, economic, and environmental network. This perspective, we hope, will allow us to understand the characteristics of human health that emerge from an time-hewn dynamic equilibrium with the world within and around us.
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- 2014
15. Possible quenching of static neutron pairing near the N=98 deformed shell gap: Rotational structures in Gd160,161
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Sanna Stolze, T. Lauritsen, John P. Greene, A. J. Boston, J. Li, G. L. Wilson, S. Zhu, J. Heery, Jayne Simpson, C. R. Hoffman, P. Jackson, F. G. Kondev, K. Villafana, Guy Savard, E. S. Paul, M. P. Carpenter, D. Little, S. Frauendorf, M. A. Riley, Kalle Auranen, Jin Wu, D. J. Hartley, R. V. F. Janssens, Jill S. Baron, Jason A. Clark, D. Seweryniak, and A. D. Ayangeakaa
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Quenching ,Physics ,Pairing ,Shell (structure) ,Neutron ,Molecular physics - Published
- 2021
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16. First candidates for γ vibrational bands built on the [505]11/2− neutron orbital in odd- A Dy isotopes
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J. Simpson, J. N. Orce, Catherine Scholey, Sanna Stolze, T. Lauritsen, A. Korichi, L. Makhathini, P. Ruotsalainen, O. Shirinda, I. Stefanescu, F. G. Kondev, J. F. Sharpey-Schafer, C. W. Beausang, D. G. Roux, N. Cooper, R. A. Bark, J. Hirvonen, Paul Greenlees, D. Miller, L. Mdletshe, B. J. P. Gall, V. Werner, E. A. McCutchan, S. N. T. Majola, E. A. Lawrie, X. Wang, Pauli Peura, J. L. Wood, S. Miller, J. Ndayishimye, C. J. Chiara, S. P. Bvumbi, Juha Sorri, Juha Uusitalo, D. Hartley, L. L. Riedinger, N. Redon, L. Bianco, Jan Sarén, S. H. Mthembu, M. A. Riley, L. Msebi, S. S. Ntshangase, Ulrika Jakobsson, B. Maqabuka, T. S. Dinoko, W. D. Kulp, J. M. Allmond, M. P. Carpenter, Peter B. Jones, G. Zimba, B. M. Nyakó, Rauno Julin, József Tímár, S. Zhu, B. V. Kheswa, Paivi Nieminen, T. D. Bucher, M. A. Sithole, P. Z. Ngcobo, Panu Rahkila, Sakari Juutinen, D. Curien, A. Minkova, D. M. Cullen, J. Piot, Steffen Ketelhut, C. H. Yu, P. L. Masiteng, and P. E. Garrett
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Physics ,Coupling ,Isotope ,010308 nuclear & particles physics ,Nuclear structure ,01 natural sciences ,7. Clean energy ,Excited state ,0103 physical sciences ,Vibrational bands ,Neutron ,Gammasphere ,Atomic physics ,010306 general physics ,Spin (physics) - Abstract
Rotational structures have been measured using the Jurogam II and GAMMASPHERE arrays at low spin following the Gd155(α,2n)Dy157 and Nd148(C12,5n)Dy155 reactions at 25 and 65 MeV, respectively. We report high-K bands, which are conjectured to be the first candidates of a Kπ=2+γ vibrational band, built on the [505]11/2− neutron orbital, in both odd-ADy155,157 isotopes. The coupling of the first excited K=0+ states or the so-called β vibrational bands at 661 and 676 keV in Dy154 and Dy156 to the [505]11/2− orbital, to produce a Kπ=11/2− band, was not observed in both Dy155 and Dy157, respectively. The implication of these findings on the interpretation of the first excited 0+ states in the core nuclei Dy154 and Dy156 are also discussed.
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- 2020
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17. COVID-19: responding to a pandemic on Operation TORAL
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M R Riley, Stacey Webster, A Gough, and S Makin
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2019-20 coronavirus outbreak ,Economic growth ,medicine.medical_specialty ,Behaviour change ,Coronavirus disease 2019 (COVID-19) ,Multinational corporation ,Public health ,Political science ,Pandemic ,medicine ,General Medicine ,Occupational safety and health ,Health policy - Abstract
Operation TORAL was the UK’s contribution to NATO’s Operation RESOLUTE SUPPORT in Kabul, Afghanistan. Approximately 1000 British troops were deployed in Kabul when the arrival of the COVID-19 pandemic in Afghanistan was declared. This article will describe the challenges faced due to COVID-19 in Kabul.Medical planning considerations, occupational health issues, implementation of behaviour change and operating as part of a multinational organisation are all discussed, with challenges encountered detailed and potential solutions offered. The use of a suggested framework for ensuring the medical estimate process covered all areas relevant to an emerging viral pandemic —the 4Ds and 4Cs approach—proved particularly useful in the early stages of the pandemic in Afghanistan.
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- 2021
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18. UK Role 4 military infectious diseases and tropical medicine cases in 2005–2013
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A Mason, M R Riley, Mark S. Bailey, and D S Burns
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Hospitals, Military ,Infections ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Ambulatory care ,Ambulatory Care ,medicine ,Humans ,030212 general & internal medicine ,Quality of Health Care ,Retrospective Studies ,Medical treatment ,business.industry ,030208 emergency & critical care medicine ,Retrospective cohort study ,Health Care Costs ,General Medicine ,Middle Aged ,Service personnel ,medicine.disease ,United Kingdom ,Hospitalization ,Medical services ,Military personnel ,Military Personnel ,Sick leave ,Tropical medicine ,Female ,Medical emergency ,Sick Leave ,business - Abstract
IntroductionInfectious diseases are a frequent cause of morbidity among British troops. The aim of this paper is to describe the spectrum of infectious diseases seen when UK service personnel are evacuated for definitive care to the Role 4 Medical Treatment Facility based at Birmingham Heartlands Hospital.MethodA retrospective analysis of all military patients presenting with infectious diseases and treated at Birmingham Heartlands Hospital between 14 April 2005 and 31 December 2013 was undertaken.ResultsDuring this period, 502 patients were identified. Infections originated in 49 countries, most commonly Afghanistan (46% cases), the UK (10% cases) and Belize (9% of cases). The most common presentations were dermatological conditions, gastroenterological illnesses and undifferentiated fevers.ConclusionUK service personnel in significant numbers continue to suffer a wide range of infectious diseases, acquired throughout the globe, which often require specialist tertiary infection services to diagnose and manage. Future prospective data collection is recommended to identify trends, which in turn will inform military training needs and future research priorities in the Defence Medical Services (DMS) and allows development of appropriate policies and clinical guidelines for management of DMS personnel with infectious diseases.
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- 2017
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19. A Study of Wire Breakup and In-Flight Particle Behavior During Wire Flame Spraying of Aluminum
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M. A. Riley, D.G. McCartney, and G. D. Lunn
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Materials science ,Metallurgy ,Gas dynamic cold spray ,chemistry.chemical_element ,02 engineering and technology ,Plasma transferred wire arc thermal spraying ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Breakup ,Surfaces, Coatings and Films ,Plume ,Spray nozzle ,020303 mechanical engineering & transports ,0203 mechanical engineering ,chemistry ,Aluminium ,Materials Chemistry ,Particle imaging ,Particle ,Composite material ,0210 nano-technology - Abstract
Although wire flame spraying has been used for many years, there has been relatively little attention given to understanding the process dynamics. In this work, imaging of the molten wire tip, particle imaging using the Oseir Spray Watch system and particle capture (wipe tests) have all been employed to quantify plume behaviour. Aluminium wire feedstock is melted and then breaks-up close to the exit of the spray nozzle in a non-axisymmetric manor. The mean velocity and diameter of the particles detected by the Spray Watch system change little with stand-off distance with values of approximately 280 m/s and 70 μm respectively for the spray parameters employed. The particle diagnostic system could not detect particles ⪅ 45 μm in diameter and it is estimated that these account for no more than 53 % of the sprayed material. Overall, wire flame spraying generates a surprisingly stable particle stream.
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- 2017
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20. White paper on nuclear astrophysics and low-energy nuclear physics, Part 2: Low-energy nuclear physics
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L. G. Sobotka, C. R. Howell, J. B. Natowitz, Carl J Gross, Guy Savard, Michael P. Carpenter, Thomas Papenbrock, R. F. Casten, Martin J. Savage, Witold Nazarewicz, Charlotte Elster, Elizabeth A. McCutchen, A. H. Wuosmaa, Alexandra Gade, K. L. Jones, Sherry Yennello, P. Fallon, M. A. Stoyer, B. M. Sherrill, Gaute Hagen, Kai Vetter, M. A. Riley, Charles Horowitz, A. O. Macchiavelli, Ingo Wiedenhoever, Suzanne E. Lapi, Sanjay Reddy, Douglas Higinbotham, J. Carlson, Anna Hayes, M. Betty Tsang, and Filip G Kondev
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Physics ,Nuclear and High Energy Physics ,Enthusiasm ,010308 nuclear & particles physics ,media_common.quotation_subject ,Nuclear data ,Plan (drawing) ,01 natural sciences ,Nuclear physics ,White paper ,Low energy ,Anticipation (artificial intelligence) ,0103 physical sciences ,Nuclear astrophysics ,Nuclear science ,010306 general physics ,media_common - Abstract
Over the last decade, the Low-Energy Nuclear Physics (LENP) and Nuclear Astrophysics (NAP) communities have increasingly organized themselves in order to take a coherent approach to resolving the challenges they face. As a result, there is a high level of optimism in view of the unprecedented opportunities for substantial progress. In preparation of the 2015 US Nuclear Science Long Range Plan (LRP), the two American Physical Society Division of Nuclear Physics town meetings on LENP and NAP were held jointly on August 21–23, 2014, at Texas A&M, College Station, in Texas. These meetings were co-organized to take advantage of the strong synergy between the two fields. The present White Paper attempts to communicate the sense of great anticipation and enthusiasm that came out of these meetings. A unanimously endorsed set of joint resolutions condensed from the individual recommendations of the two town meetings were agreed upon. The present LENP White Paper discusses the above and summarizes in detail for each of the sub-fields within low-energy nuclear physics, the major accomplishments since the last LRP, the compelling near-term and long-term scientific opportunities plus the resources needed to achieve these goals, along with the scientific impact on, and interdisciplinary connections to, other fields.
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- 2017
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21. β and γ bands in N=88 , 90, and 92 isotones investigated with a five-dimensional collective Hamiltonian based on covariant density functional theory: Vibrations, shape coexistence, and superdeformation
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B. V. Kheswa, Peter B. Jones, A. Minkova, Z. P. Li, D. Negi, D. M. Cullen, R. Lindsay, O. Shirinda, B. M. Nyakó, R. A. Bark, R. Newman, T. S. Dinoko, D. G. Aschman, Jan Sarén, P. I. Mashita, L. L. Riedinger, R. Ntshodu, J. E. Easton, J. Hirvonen, S. Jongile, P. Papka, L. Msebi, Sanna Stolze, J. F. Sharpey-Schafer, N. A. Khumalo, Ulrika Jakobsson, M. Wiedeking, E. A. Lawrie, S. P. Bvumbi, Paul Greenlees, A. Korichi, Juha Sorri, P. Ruotsalainen, M. Stankiewicz, A. Netshiya, S. S. Ntshangase, Sakari Juutinen, Catherine Scholey, József Tímár, J. Ndayishimye, M. A. Riley, D. G. Roux, S. N. T. Majola, Pauli Peura, Steffen Ketelhut, K. L. Malatji, D. Hartley, T. E. Madiba, S. M. Mullins, P. A. Vymers, S. Q. Zhang, M. A. Sithole, Juha Uusitalo, P. L. Masiteng, T. D. Bucher, B. Y. Song, L. Makhathini, Panu Rahkila, N. Erasmus, G. Zimba, Z. Shi, S. M. Maliage, B. Maqabuka, L. Mdletshe, J. J. Lawrie, and Rauno Julin
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Physics ,010308 nuclear & particles physics ,Nuclear structure ,01 natural sciences ,Hamiltonian system ,Superdeformation ,Vibration ,symbols.namesake ,Quantum mechanics ,0103 physical sciences ,symbols ,Density functional theory ,Covariant transformation ,010306 general physics ,Hamiltonian (quantum mechanics) - Abstract
CITATION: Majola, S. N. T. et al. 2019. β and γ bands in N=88, 90, and 92 isotones investigated with a five-dimensional collective Hamiltonian based on covariant density functional theory: Vibrations, shape coexistence, and superdeformation. Physical Review C, 100(4). doi:10.1103/PhysRevC.100.044324.
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- 2019
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22. Spectroscopy of low-spin states in Dy157 : Search for evidence of enhanced octupole correlations
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L. Bianco, Robert Bark, B. M. Nyakó, T. D. Bucher, P. L. Masiteng, J. Ndayishimye, Steffen Ketelhut, E. A. Lawrie, G. Zimba, L. Mdletshe, O. Shirinda, Peter B. Jones, C. Scholey, S. S. Ntshangase, D. M. Cullen, R. T. Newman, Pauli Peura, D. J. Hartley, S. N. T. Majola, J.F. Sharpey-Schafer, A. Minkova, S. P. Bvumbi, B. V. Kheswa, B. Maqabuka, Ulrika Jakobsson, Juha Sorri, Juha Uusitalo, P. Ruotsalainen, S. Juutinen, J. Hirvonen, M. A. Riley, Sanna Stolze, József Tímár, P. Rahkila, D. G. Roux, P. E. Garrett, A. Sithole, Paivi Nieminen, R. Julin, L. L. Riedinger, Jan Sarén, A. Korichi, and Paul Greenlees
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Physics ,Nuclear physics ,Spin states ,010308 nuclear & particles physics ,0103 physical sciences ,Nuclear structure ,010306 general physics ,Spectroscopy ,01 natural sciences ,Nuclear theory ,3. Good health - Abstract
CITATION: Majola, S. N. T., et al. 2019. Spectroscopy of low-spin states in 157Dy : Search for evidence of enhanced octupole correlations. Physical Review C, 100(6):034322, doi:10.1103/PhysRevC.100.034322.
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- 2019
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23. Backbending, seniority, and Pauli blocking of pairing correlations at high rotational frequencies in rapidly rotating nuclei
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S. Zhu, E. A. McCutchan, M. P. Carpenter, P. F. Bertone, T. Lauritsen, Alexander Volya, J. Cavey, P. Chowdhury, J. T. Matta, J.F. Sharpey-Schafer, E.G. Jackson, K. Villafana, J. J. Carroll, F. G. Kondev, C. J. Chiara, S. S. Hota, A. D. Ayangeakaa, A. J. Boston, D. J. Hartley, Jayne Simpson, Xuan Wang, Saul L. Miller, S. Mukhopadhyay, R. V. F. Janssens, E. S. Paul, M. A. Riley, Jill S. Baron, U. Garg, Marc Litz, W. C. Ma, J. R. Vanhoy, P. J. Nolan, E. E. Pedicini, and L. L. Riedinger
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Physics ,symbols.namesake ,Pauli exclusion principle ,Blocking (radio) ,Quantum mechanics ,Pairing ,symbols ,Seniority - Abstract
Garrett et al. systematically investigated band-crossing frequencies resulting from the rotational alignment of the first pair of i13/2 neutrons (AB) in rare-earth nuclei. In that study, evidence was found for an odd-even neutron number dependence attributed to changes in the strength of neutron pairing correlations. The present paper carries out a similar investigation at higher rotational frequencies for the second pair of aligning i13/2 neutrons (BC). Again, a systematic difference in band-crossing frequencies is observed between odd-N and even-N Er, Yb, Hf, and W nuclei, but in the BC case, it is opposite to the AB neutron-number dependence. These results are discussed in terms of a reduction of neutron pairing correlations at high rotational frequencies and of the effects of Pauli blocking on the pairing field by higher-seniority configurations. Also playing a significant role are the changes in deformation with proton and neutron numbers, the changes in location of single-particle orbitals as a function of quadrupole deformation, and the position of the Fermi surface with regard to the various ω components of the neutron i13/2 shell.
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- 2019
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24. Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma
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Mingjian James You, M. F. Riley, Guillermina Lozano, and Asha S. Multani
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0301 basic medicine ,Genome instability ,Cancer Research ,Lymphoma, B-Cell ,p73 ,Apoptosis ,Biology ,Article ,law.invention ,Animals, Genetically Modified ,Mice ,03 medical and health sciences ,Mdm2 ,law ,Genetics ,medicine ,Animals ,Humans ,Tumor Protein p73 ,skin and connective tissue diseases ,B-cell lymphoma ,neoplasms ,Molecular Biology ,Regulation of gene expression ,Tumor Suppressor Proteins ,Nuclear Proteins ,Proto-Oncogene Proteins c-mdm2 ,Fibroblasts ,genomic instability ,medicine.disease ,Lymphoma ,DNA-Binding Proteins ,Gene Expression Regulation, Neoplastic ,Disease Models, Animal ,enzymes and coenzymes (carbohydrates) ,030104 developmental biology ,Proto-Oncogene Proteins c-bcl-2 ,Cancer research ,biology.protein ,Suppressor ,Tumor Suppressor Protein p53 - Abstract
Many human tumors express high levels of the p53 inhibitor Mdm2, resulting from amplification of the Mdm2 locus or aberrant post-translational regulation of the Mdm2 protein. While the importance of Mdm2 in regulating p53 is clear, Mdm2 also has p53-independent roles. For example, overexpression of Mdm2 results in genomic instability in a p53-independent manner. In addition, Mdm2 has many additional binding partners, some of which, such as the tumor suppressor p73, have also been implicated in genomic instability. In this study, cells and tumors with Mdm2 overexpression and p73 loss exhibit increased genomic instability as compared with either alteration alone and cooperate in development of B-cell lymphomagenesis. Cytogenetic analysis of mouse embryonic fibroblasts and pre-malignant B cells demonstrates that loss of p73 exacerbates the chromosome breaks and fusions observed in Mdm2(Tg) cells. B-cell lymphomas from Mdm2(Tg);p73(+/-) mice retain the remaining p73 allele, exhibit elevated levels of the antiapoptotic protein Bcl2 and thus dampen apoptosis. In summary, Mdm2 overexpression and p73 loss cooperate in genomic instability and tumor development, indicating that the oncogenic function of Mdm2 is a combined effect of inhibiting p53 and p73 functions. Given that p73 is lost or silenced in human B-cell lymphomas, the Mdm2(Tg);p73(+/-) mouse serves as a model for human disease and may provide additional insight into the pathways that contribute to B-cell lymphomagenesis.
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- 2015
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25. Vancomycin Concentrations in Paraspinal Muscles During Posterior Spinal Fusions for Neuromuscular Scoliosis
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Sarah M. Brown-Riley, June C. Smith, Scott J. Luhmann, Alexis Elward, and James R. Gregory
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Male ,Adolescent ,medicine.medical_treatment ,Paraspinal Muscles ,Renal function ,Scoliosis ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Vancomycin ,medicine ,Humans ,Surgical Wound Infection ,Orthopedics and Sports Medicine ,Prospective Studies ,Prospective cohort study ,Child ,030222 orthopedics ,business.industry ,Antibiotic Prophylaxis ,medicine.disease ,Anti-Bacterial Agents ,Spinal Fusion ,Spinal fusion ,Anesthesia ,Female ,business ,Complication ,Surgical incision ,030217 neurology & neurosurgery ,Kidney disease ,medicine.drug - Abstract
Study Design Prospective consecutively enrolled cohort. Objectives To evaluate paraspinal muscle concentration of intravenously administered vancomycin, at predetermined time points, during posterior spinal fusion (PSF) with instrumentation in neuromuscular scoliosis (NMS). Summary Surgical site infection (SSI) after PSF for NMS can be a devastating complication, which may lead to prolonged antibiotic use, multiple additional surgical procedures, pseudarthroses, and sepsis. Because of significant morbidity of SSIs in NMS, the prophylactic use of vancomycin has been adopted at our institution as standard wound prophylaxis, despite any high-level evidence of its efficacy. Methods A prospective study of 20 patients who underwent definitive PSF for NMS and received vancomycin infusion preoperatively per institutional protocol. Serum levels were obtained immediately after infusion, at surgical incision, and then at 1, 2, and 4 hours post incision. Muscle tissue samples were simultaneously obtained at incision and at 1, 2, and 4 hours post incision. Samples were analyzed by a validated liquid chromatography–tandem mass spectrometry method. Results 10 males and 10 females with a mean age of 14+11 years (9–20 years) received a mean infusion of 15.0 mg/kg vancomycin. Mean serum levels were 26.7 μg/mL after infusion, 18.1 at incision, 13.2 at 1 hour, 11.8 at 2 hours, and 7.6 at 4 hours post infusion. Mean muscle levels were 0.5 μg/mL at incision, 0.6 at 1 hour, 0.5 at 2 hours, and 0.7 at 4 hours post infusion. Mean serum levels reached minimum inhibitory concentration (MIC) for Staphylococcus aureus at incision and at all timepoints during surgery. Mean muscle vancomycin levels never reached MIC. No patients had any cardiac or kidney disease, and all patients had normal kidney function according to their preoperative laboratory values. Conclusions Using accepted guidelines for the administration of intravenous vancomycin preoperatively, serum levels reached MIC at incision and at all timepoints tested during PSF for neuromuscular scoliosis. At no timepoint tested did muscle levels reach MIC. Level of Evidence Level II.
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- 2017
26. High spin spectroscopy in Ra219 : Search for the lower mass boundary of the region of statically octupole-deformed nuclei
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B. Abromeit, D. D. Caussyn, Nabin Rijal, Lagy Baby, R. Dungan, Vandana Tripathi, M. Anastasiou, K. Villafana, K. W. Kemper, Saul L. Miller, Jill S. Baron, P.-L. Tai, P. D. Cottle, R. S. Lubna, M. A. Riley, S. L. Tabor, and T. C. Hensley
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Physics ,010308 nuclear & particles physics ,0103 physical sciences ,Parity (physics) ,Atomic physics ,010306 general physics ,Spectroscopy ,01 natural sciences - Abstract
We report the results of a study of rotational bands in $^{219}\mathrm{Ra}$ via the $^{208}\mathrm{Pb}(^{14}\mathrm{C},3n)$ reaction to look for evidence that this nucleus is statically octupole deformed. We add 19 $\ensuremath{\gamma}$ rays not previously observed to the level scheme and extend the two most strongly populated alternating parity bands to $J=51/2$ and 45/2. The magnitude of the energy splitting between the spin-parity doublets in the two bands appears to exclude the possibility that $^{219}\mathrm{Ra}$ has a static octupole deformation.
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- 2017
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27. Electromagnetic Moments of Radioactive Te136 and the Emergence of Collectivity 2p⊕2n Outside of Double-Magic Sn132
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Andrew Stuchbery, A. Galindo-Uribarri, J. M. Allmond, R. L. Varner, A. Gargano, Elizabeth Padilla-Rodal, D. W. Stracener, Nunzio Itaco, C. R. Bingham, D. C. Radford, L. Coraggio, M. Danchev, Paul Hausladen, C. Baktash, C.-H. Yu, A. Covello, Carl J Gross, K. Lagergren, B. A. Brown, J. Pavan, N. J. Stone, and M. A. Riley
- Subjects
Physics ,Valence (chemistry) ,Proton ,010308 nuclear & particles physics ,Nuclear Theory ,SHELL model ,General Physics and Astronomy ,Coulomb excitation ,Prolate spheroid ,01 natural sciences ,Excited state ,0103 physical sciences ,Neutron ,Atomic physics ,010306 general physics ,Wave function - Abstract
Radioactive ^{136}Te has two valence protons and two valence neutrons outside of the ^{132}Sn double shell closure, providing a simple laboratory for exploring the emergence of collectivity and nucleon-nucleon interactions. Coulomb excitation of ^{136}Te on a titanium target was utilized to determine an extensive set of electromagnetic moments for the three lowest-lying states, including B(E2;0_{1}^{+}→2_{1}^{+}), Q(2_{1}^{+}), and g(2_{1}^{+}). The results indicate that the first-excited state, 2_{1}^{+}, composed of the simple 2p⊕2n system, is prolate deformed, and its wave function is dominated by excited valence neutron configurations, but not to the extent previously suggested. It is demonstrated that extreme sensitivity of g(2_{1}^{+}) to the proton and neutron contributions to the wave function provides unique insight into the nature of emerging collectivity, and g(2_{1}^{+}) was used to differentiate among several state-of-the-art theoretical calculations. Our results are best described by the most recent shell model calculations.
- Published
- 2017
- Full Text
- View/download PDF
28. Isomeric Character of the Lowest Observed 4+ State in S44
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D. Weisshaar, H. Iwasaki, Alexander Volya, D. M. McPherson, Daniel Bazin, J. J. Parker, K. Whitmore, P. D. Cottle, H. L. Crawford, Daniel Santiago-Gonzalez, Alexandra Gade, A. Lemasson, M. A. Riley, A. O. Macchiavelli, F. Recchia, Jeff Baker, C. Morse, T. N. Ginter, C. Loelius, S. R. Stroberg, Kathrin Wimmer, D. Smalley, I. Wiedenhöver, V. M. Bader, and T.R. Baugher
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Physics ,010308 nuclear & particles physics ,General Physics and Astronomy ,State (functional analysis) ,16. Peace & justice ,01 natural sciences ,Recoil ,medicine.anatomical_structure ,Character (mathematics) ,0103 physical sciences ,medicine ,Atomic physics ,010306 general physics ,Ground state ,Low Mass ,Nucleus - Abstract
Previous experiments observed a 4^{+} state in the N=28 nucleus ^{44}S and suggested that this state may exhibit a hindered E2-decay rate, inconsistent with being a member of the collective ground state band. We populate this state via two-proton knockout from a beam of exotic ^{46}Ar projectiles and measure its lifetime using the recoil distance method with the GRETINA γ-ray spectrometer. The result, 76(14)_{stat}(20)_{syst} ps, implies a hindered transition of B(E2;4^{+}→2_{1}^{+})=0.61(19) single-particle or Weisskopf units strength and supports the interpretation of the 4^{+} state as a K=4 isomer, the first example of a high-K isomer in a nucleus of such low mass.
- Published
- 2017
- Full Text
- View/download PDF
29. Investigation of negative-parity states in Dy156 : Search for evidence of tetrahedral symmetry
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M. A. Riley, Scott L. Miller, E. A. McCutchan, W. D. Kulp, J. L. Wood, T. Lauritsen, S. Zhu, R. V. F. Janssens, J. M. Allmond, C.-H. Yu, J. Piot, D.W. Miller, Xuan Wang, I. Stefanescu, F. G. Kondev, N. Cooper, S. N. T. Majola, B. J. P. Gall, L. L. Riedinger, J.F. Sharpey-Schafer, P. E. Garrett, J. Dudek, C. J. Chiara, D. Curien, D. J. Hartley, C. W. Beausang, M. P. Carpenter, J. Simpson, V. Werner, and N. Redon
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Physics ,Rare earth nuclei ,Light nucleus ,Particle physics ,010308 nuclear & particles physics ,Hadron ,Nuclear structure ,Parity (physics) ,Elementary particle ,Tetrahedral symmetry ,01 natural sciences ,Baryon ,Quantum mechanics ,0103 physical sciences ,010306 general physics - Published
- 2017
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- View/download PDF
30. Nuclear shape coexistence in 194Hg
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C. W. Beausang, C. A. Kalfas, R. Vlastou, E. S. Paul, Malcolm J. Joyce, S. Kossionides, M. A. Riley, M. Serris, Sotirios Harissopulos, R. Wadsworth, N. Fotiades, Peter B. Jones, K. Hauschild, P.D. Forsyth, D. M. Cullen, R. M. Clark, P. Fallon, Jayne Simpson, P.J. Twin, S.J. Gale, J.F. Sharpey-Schafer, C. T. Papadopoulos, and P. J. Dagnall
- Subjects
Condensed matter physics ,Nuclear Experiment ,Nuclear shape - Abstract
High spin states in the isotope 194Hg were populated using the 150Nd (48Ca,4n) reaction at a beam energy of 213 MeV. A sequence of dip ole transitions has been observed above 8 MeV excitation energy. Cross-over transitions have also been identified. An interpretation connecting this sequence to a nuclear shape change is attempted. A comparison with similar structures in the neighbouring Hg isotopes is also attempted.
- Published
- 2019
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31. Development of a Patient-Centered Bilingual Prescription Drug Label
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Sunil Kripalani, M. Brian Riley, Jennie Mashburn, Karen M. Trochez, Arun Mohan, Callie Jennings, Phillip Johnston, and Dane R Boyington
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Adult ,Male ,medicine.medical_specialty ,Health (social science) ,Prescription drug ,Prescription Drugs ,Alternative medicine ,Multilingualism ,Library and Information Sciences ,030226 pharmacology & pharmacy ,03 medical and health sciences ,0302 clinical medicine ,Patient-Centered Care ,medicine ,Humans ,030212 general & internal medicine ,Medical prescription ,Qualitative Research ,computer.programming_language ,Drug Labeling ,Communication ,Medical education ,business.industry ,Public Health, Environmental and Occupational Health ,Focus Groups ,Middle Aged ,Focus group ,3. Good health ,Table (database) ,Female ,Icon ,business ,computer ,Qualitative research ,Research Article - Abstract
Research shows that prescription drug labels are often difficult for patients to understand, which contributes to medication errors and nonadherence. In this study, the authors developed and qualitatively evaluated an evidence-based bilingual prescription container label designed to improve understanding. The authors developed several prototypes in English only or in English and Spanish. The labels included an image of the drug, an icon to show its purpose, and plain-language instructions presented in a 4-time-of-day table. In 5 focus groups and interviews that included 57 participants, patients and pharmacists critically reviewed the designs and compared them with traditional medication labels and reformatted labels without illustrations. Patients strongly preferred labels that grouped patient-relevant content, highlighted key information, and included drug indication icons. They also preferred having the 4-time-of-day table and plain-language text instructions as opposed to either one alone. Patients preferred having pertinent warnings on the main label instead of auxiliary labels. Pharmacists and Latino patients valued having Spanish and English instructions on the label, so both parties could understand the content. The final label design adheres to the latest national- and state-level recommendations for label format and incorporates additional improvements on the basis of patient and pharmacist input. This design may serve as a prototype for improving prescription drug labeling.
- Published
- 2013
32. A severe outbreak of chickpea viruses in northern New South Wales, Australia, during 2012
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Mohammad Aftab, M. J. Riley, A. Bowring, W. Manning, and J. A. G. van Leur
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biology ,Beet western yellows virus ,viruses ,fungi ,Luteovirus ,Potyvirus ,food and beverages ,Outbreak ,Plant Science ,biology.organism_classification ,Virus ,Cucumber mosaic virus ,Agronomy ,Alfalfa mosaic virus ,Turnip mosaic virus ,Agronomy and Crop Science - Abstract
Chickpea crops in northern NSW during 2012 showed an unusual high incidence of severe virus symptoms, mainly related to infection by Beet western yellows virus (BWYV) with minor incidences of Alfalfa mosaic virus (AMV) and Cucumber mosaic virus (CMV). Canola and turnip weed close to surveyed chickpea paddocks showed high BWYV and Turnip mosaic virus (TuMV) incidences and have likely played an important role in the BWYV epidemic in chickpeas.
- Published
- 2013
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- View/download PDF
33. Evaluation of fatty acid methyl ester profile and amplified fragment length polymorphism analyses to distinguish five species ofPhytophthoraassociated with ornamental plants
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C.-H. Duan, M. B. Riley, and S. N. Jeffers
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chemistry.chemical_compound ,chemistry ,fungi ,Botany ,Ornamental plant ,food and beverages ,Amplified fragment length polymorphism ,Phytophthora ,Biology ,biology.organism_classification ,Agronomy and Crop Science ,Fatty acid methyl ester - Abstract
Fatty acid methyl ester (FAME) profiles and amplified fragment length polymorphisms (AFLPs) were evaluated as tools for identifying species of Phytophthora. Five isolates of each of Phytophthora ca...
- Published
- 2013
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34. ESSAY - Spectrum Synergy: Policy Opportunities to Promote Communications and Information Flow in Wireless Networks
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M. Chris Riley
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Public Administration ,Sociology and Political Science ,Computer science ,Management science ,Wireless network ,business.industry ,Communication ,Information flow (information theory) ,Telecommunications ,business ,Spectrum (topology) - Abstract
Will consumers and democracy benefit or lose from future mobile policy? In this essay that introduces the “Spectrum for Democracy” special issue of Journal of Information Policy, Dr. Riley argues that the key question is whether national and international policy will facilitate or frustrate the opportunities that wireless presents. To address the biggest challenges, he advocates emphasis on “Super Wi-Fi,” increased competition, spectrum standardization, interoperable architectures, mobile broadband universal service, and resistance to state censorship. In the long-term, Riley says, spectrum management should move away from the current model to a completely opportunistic, software-defined cognitive radio technology.
- Published
- 2013
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- View/download PDF
35. Electromagnetic Moments of Radioactive ^{136}Te and the Emergence of Collectivity 2p⊕2n Outside of Double-Magic ^{132}Sn
- Author
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J M, Allmond, A E, Stuchbery, C, Baktash, A, Gargano, A, Galindo-Uribarri, D C, Radford, C R, Bingham, B A, Brown, L, Coraggio, A, Covello, M, Danchev, C J, Gross, P A, Hausladen, N, Itaco, K, Lagergren, E, Padilla-Rodal, J, Pavan, M A, Riley, N J, Stone, D W, Stracener, R L, Varner, and C-H, Yu
- Abstract
Radioactive ^{136}Te has two valence protons and two valence neutrons outside of the ^{132}Sn double shell closure, providing a simple laboratory for exploring the emergence of collectivity and nucleon-nucleon interactions. Coulomb excitation of ^{136}Te on a titanium target was utilized to determine an extensive set of electromagnetic moments for the three lowest-lying states, including B(E2;0_{1}^{+}→2_{1}^{+}), Q(2_{1}^{+}), and g(2_{1}^{+}). The results indicate that the first-excited state, 2_{1}^{+}, composed of the simple 2p⊕2n system, is prolate deformed, and its wave function is dominated by excited valence neutron configurations, but not to the extent previously suggested. It is demonstrated that extreme sensitivity of g(2_{1}^{+}) to the proton and neutron contributions to the wave function provides unique insight into the nature of emerging collectivity, and g(2_{1}^{+}) was used to differentiate among several state-of-the-art theoretical calculations. Our results are best described by the most recent shell model calculations.
- Published
- 2016
36. First observation of rotational structures in Re168
- Author
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E. A. McCutchan, P. Chowdhury, T. Lauritsen, S. S. Hota, E. E. Pedicini, D. J. Hartley, C. J. Chiara, F. G. Kondev, J. T. Matta, J. R. Vanhoy, R. V. F. Janssens, U. Garg, Saul L. Miller, S. Zhu, S. Mukhopadhyay, M. A. Riley, W. C. Ma, L. L. Riedinger, M. P. Carpenter, P. F. Bertone, Xuan Wang, G. Gürdal, and A. D. Ayangeakaa
- Subjects
Physics ,Spins ,chemistry ,010308 nuclear & particles physics ,0103 physical sciences ,chemistry.chemical_element ,Multiplicity (chemistry) ,Atomic physics ,Rhenium ,010306 general physics ,01 natural sciences ,Energy (signal processing) ,Spin-½ - Abstract
The first rotational sequences have been assigned to the odd-odd nucleus $^{168}\mathrm{Re}$. Coincidence relationships of these structures with rhenium x rays confirm the isotopic assignment, while arguments based on the $\ensuremath{\gamma}$-ray multiplicity ($K$-fold) distributions observed with the new bands lead to the mass assignment. Configurations for the two bands were determined through analysis of the rotational alignments of the structures and a comparison of the experimental $B(M1)/B(E2)$ ratios with theory. Tentative spin assignments are proposed for the $\ensuremath{\pi}{h}_{11/2}\ensuremath{\nu}{i}_{13/2}$ band, based on energy level systematics for other known sequences in neighboring odd-odd rhenium nuclei, as well as on systematics seen for the signature inversion feature that is well known in this region. The spin assignment for the $\ensuremath{\pi}{h}_{11/2}\ensuremath{\nu}({h}_{9/2}/{f}_{7/2})$ structure provides additional validation of the proposed spins and configurations for isomers in the $^{176}\mathrm{Au} \ensuremath{\rightarrow} ^{172}\mathrm{Ir}\ensuremath{\rightarrow}^{168}\mathrm{Re} \ensuremath{\alpha}$-decay chain.
- Published
- 2016
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- View/download PDF
37. Direct Evidence of Octupole Deformation in Neutron-Rich ^{144}Ba
- Author
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Ching-Yen Wu, C. M. Campbell, D. Seweryniak, H. M. David, S. Zhu, A. L. Richard, E. T. Gregor, M. P. Carpenter, C. J. Chiara, F. G. Kondev, A. Wiens, M. Cromaz, Brian Bucher, Marcus Scheck, B. P. Kay, Calem Hoffman, Mallory Smith, A. B. Hayes, M. A. Riley, A. O. Macchiavelli, A. D. Ayangeakaa, P. A. Butler, R. V. F. Janssens, Guy Savard, Clayton Dickerson, T. Lauritsen, J. Harker, H. L. Crawford, Jason A. Clark, R. C. Pardo, R. C. Vondrasek, D. Cline, A. Korichi, M. Albers, Centre de Sciences Nucléaires et de Sciences de la Matière (CSNSM SNO), and Université Paris-Saclay-Univ. Paris-Sud-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)
- Subjects
General Physics ,Direct evidence ,General Physics and Astronomy ,FOS: Physical sciences ,Coulomb excitation ,[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] ,nucl-ex ,01 natural sciences ,Mathematical Sciences ,Indirect evidence ,ENERGY ,Engineering ,0103 physical sciences ,medicine ,Neutron ,Matrix element ,Nuclear Experiment (nucl-ex) ,010306 general physics ,Nuclear Experiment ,Physics ,[PHYS]Physics [physics] ,PARITY ,010308 nuclear & particles physics ,RADIOACTIVE BEAMS ,DEFORMED-NUCLEI ,medicine.anatomical_structure ,BARIUM ISOTOPES ,GROUND-STATE ,Physical Sciences ,Atomic physics ,Deformation (engineering) ,Nucleus ,Beam (structure) - Abstract
The neutron-rich nucleus $^{144}$Ba ($t_{1/2}$=11.5 s) is expected to exhibit some of the strongest octupole correlations among nuclei with mass numbers $A$ less than 200. Until now, indirect evidence for such strong correlations has been inferred from observations such as enhanced $E1$ transitions and interleaving positive- and negative-parity levels in the ground-state band. In this experiment, the octupole strength was measured directly by sub-barrier, multi-step Coulomb excitation of a post-accelerated 650-MeV $^{144}$Ba beam on a 1.0-mg/cm$^2$ $^{208}$Pb target. The measured value of the matrix element, $\langle 3_1^- \| \mathcal{M}(E3) \| 0_1^+ \rangle=0.65(^{+17}_{-23})$ $e$b$^{3/2}$, corresponds to a reduced $B(E3)$ transition probability of 48($^{+25}_{-34}$) W.u. This result represents an unambiguous determination of the octupole collectivity, is larger than any available theoretical prediction, and is consistent with octupole deformation., Comment: 5 pages, 2 figures, 1 table, Physical Review Letters 2016
- Published
- 2016
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- View/download PDF
38. Ethnobotanical approach versus random approach in the search for new bioactive compounds: Support of a hypothesis
- Author
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Scott G. Franzblau, Phan Ke Loc, Charlotte Gyllenhaal, Somsanith Bouamanivong, Marian R. Kadushin, P. Tamez, C. Y. Ma, Truong Quang Bich, B. Southavong, M. C. Riley, Hui Xie, Ghee Teng Tan, Le Thi Xuan, L. X. Dac, Nguyen Tien Hiep, Djaja D. Soejarto, M. Xaiveu, Bethany G. Elkington, Donald P. Waller, H. T. Nguyen, Nguyen Van Hung, Nguyen Manh Cuong, John M. Pezzuto, Hongjie Zhang, Kongmany Sydara, and H. M. Ly
- Subjects
Ethnobotany ,MEDLINE ,Human immunodeficiency virus (HIV) ,Pharmaceutical Science ,medicine.disease_cause ,Article ,Drug Discovery ,Humans ,Medicine ,Pharmacology ,Plants, Medicinal ,Information retrieval ,Traditional medicine ,Plant Extracts ,business.industry ,Extramural ,General Medicine ,Print version ,Vietnam ,Complementary and alternative medicine ,Laos ,Ethnopharmacology ,Molecular Medicine ,Biological Assay ,Medicine, Traditional ,business - Abstract
Whether natural product drug discovery programs should rely on wild plants collected "randomly" from the natural environment, or whether they should also include plants collected on the basis of use in traditional medicine remains an open question.This study analyzes whether plants with ethnomedical uses from Vietnam and Laos have a higher hit rate in bioassay testing than plants collected from a national park in Vietnam with the goal of maximizing taxonomic diversity ("random" collection).All plants were extracted and subjected to bioassay in the same laboratories. Results of assays of plant collections and plant parts (samples) were scored as active or inactive based on whether any extracts had a positive result in a bioassay. Contingency tables were analyzed using χ(2) statistics.Random collections had a higher hit rate than ethnomedical collections, but for samples, ethnomedical plants were more likely to be active. Ethnomedical collections and samples had higher hit rates for tuberculosis, while samples, but not collections, had a higher hit rate for malaria. Little evidence was found to support an advantage for ethnomedical plants in HIV, chemoprevention and cancer bioassays. Plants whose ethnomedical uses directly correlated to a bioassay did not have a significantly higher hit rate than random plants.Plants with ethnomedical uses generally had a higher rate of activity in some drug discovery bioassays, but the assays did not directly confirm specific uses.Ethnomedical uses may contribute to a higher rate of activity in drug discovery screening.
- Published
- 2011
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- View/download PDF
39. Quadrupole moments of collective structures up to spin ∼65ℏ in 157Er and 158Er: A challenge for understanding triaxiality in nuclei
- Author
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C. Unsworth, S. Zhu, J. Simpson, L. L. Riedinger, P. J. Nolan, T. Lauritsen, M. A. Riley, F. G. Kondev, Martin Carpenter, H. C. Boston, J. T. Matta, J. P. Revill, R. V. F. Janssens, N. M. Lumley, C. J. Chiara, E. S. Paul, J. Ollier, D. S. Judson, Ingemar Ragnarsson, U. Garg, Susan Rigby, A. D. Ayangeakaa, Xuan Wang, D. J. Hartley, and Marina Petri
- Subjects
Physics ,Nuclear and High Energy Physics ,Short axis ,010308 nuclear & particles physics ,Nuclear Theory ,Rotation ,01 natural sciences ,0103 physical sciences ,Quadrupole ,Atomic physics ,Deformation (engineering) ,010306 general physics ,Spin (physics) ,Principal axis theorem ,Bar (unit) - Abstract
The transition quadrupole moments. Q(t), of four weakly populated collective bands up to spin similar to 65h in Er-157,Er-158 have been measured to be similar to II eb demonstrating that these sequences are associated with large deformations. However, the data are inconsistent with calculated values from cranked Nilsson-Strutinsky calculations that predict the lowest energy triaxial shape to be associated with rotation about the short principal axis. The data appear to favor either a stable triaxial shape rotating about the intermediate axis or, alternatively, a triaxial shape with larger deformation rotating about the short axis. These new results challenge the present understanding of triaxiality in nuclei. (C) 2011 Elsevier B.V. All rights reserved. (Less)
- Published
- 2011
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- View/download PDF
40. Effects of growth medium, incubation temperature, and mycelium age on production of five major fatty acids by six species ofPhytophthora
- Author
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C.-H. Duan, M. B. Riley, and S. N. Jeffers
- Subjects
chemistry.chemical_classification ,Growth medium ,biology ,Fatty acid ,biology.organism_classification ,chemistry.chemical_compound ,Incubation temperature ,Biochemistry ,chemistry ,Food science ,Phytophthora ,Gas chromatography ,Agronomy and Crop Science ,Incubation ,Fatty acid methyl ester ,Mycelium - Abstract
The effects of growth medium, incubation temperature, and mycelium age on the production of five major fatty acids by five isolates each of P. cactorum, P. citricola, P. citrophthora, P. cinnamomi, P. cryptogea, and P. nicotianae were investigated. Fatty acids were extracted from mycelia, and fatty acid methyl ester (FAME) profiles were analyzed by gas chromatography. Fifteen fatty acids were common in all species, but five of them comprised more than 75% of FAME profiles. These five fatty acids – myristic (14:0), palmitic (16:0), linoleic (18:2ω6c), oleic (18:1 ω9c), and eicosapentaenoic (20:5ω3c) acids – were used to investigate the effects of five liquid growth media (20% carrot broth, CB; 10% lima bean broth, LBB; 5% clarified V8 juice broth, V8B; ¼-strength potato dextrose broth, PDB; and ¼-strength Sabourand dextrose broth; SDB), six incubation temperatures (10, 15, 20, 25, 30, and 35°C), and four mycelium ages (4, 8, 12, and 16 days) on fatty acid production. The effect of medium on the relative pe...
- Published
- 2011
- Full Text
- View/download PDF
41. State-, parameter-, and graph-dynamics: Constraints and the distillation of postural control systems
- Author
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M. A. Riley, N. Kuznetsov, and S. Bonnette
- Subjects
State parameter ,Quantitative Biology::Neurons and Cognition ,Physiology ,Computer science ,Physics::Medical Physics ,Graph dynamics ,Physical Therapy, Sports Therapy and Rehabilitation ,Postural control ,law.invention ,Computer Science::Robotics ,Nonlinear system ,Empirical research ,law ,Control theory ,Physiology (medical) ,State (computer science) ,Distillation - Abstract
The seemingly effortless ability to maintain and adapt posture has traditionally been explained as the achievement of a single, relatively permanent postural control system. However, the extreme variability observed in postural performance challenges the idea that posture is controlled by a static system of fixed components. In this article we suggest that postural control is achieved by special-purpose, softly assembled postural devices that arise from parameter- and graph-dynamics. A brief summary of empirical studies utilizing nonlinear analyses of postural state dynamics is presented as evidence. Implications for this claim and future directions of research are also presented.
- Published
- 2011
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- View/download PDF
42. Biological evaluation of plants of Laos used in the treatment of tuberculosis in Lao traditional medicine
- Author
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Kongmany Sydara, Dennis H. Pak, Bounhong Southavong, Kongdeuane Nettavong, Onevilay Souliya, M. C. Riley, Bounleuth Thammachack, Bethany G. Elkington, Scott G. Franzblau, Djaja D. Soejarto, and Manoluck Vanthanouvong
- Subjects
Pharmacology ,medicine.medical_specialty ,Tuberculosis ,Traditional medicine ,business.industry ,education ,fungi ,Alternative medicine ,food and beverages ,Pharmaceutical Science ,General Medicine ,medicine.disease ,Article ,Southeast asia ,Complementary and alternative medicine ,Drug Discovery ,medicine ,Molecular Medicine ,business ,Medicinal plants ,Ethnomedicine ,Biological evaluation - Abstract
Tuberculosis has existed in Southeast Asia for thousands of years. Many traditional treatments involve herbal remedies. Over time, these traditional treatments have had the chance to become refined based on efficacy and safety. It was therefore hypothesized that plants that were used in the past and are still used today to treat symptoms associated with tuberculosis are more likely to contain anti-tubercular compounds than plants that have not been used continuously. To try to deduce which plants were used in Laos in the past, a collection of palm leaf manuscripts was studied and a list of plants used to treat symptoms associated with tuberculosis was compiled. Interviews were then conducted with contemporary healers to see if the same plants are still being used today. Plants that were found in the manuscripts and/or are presently used by healers were collected, extracted and were evaluated in an anti-tubercular assay. This paper presents the methods used to identify and collect plants used to treat symptoms indicative of tuberculosis, and the results of anti-TB assays to test for activity.
- Published
- 2009
- Full Text
- View/download PDF
43. MONO-AMINE OXIDASE INHIBITORS AND MENTAL SUBNORMALITY: EXPERIENCES WITH NIALAMIDE
- Author
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A. G. M. Wiseman, M. A. Riley, R. I. Mackay, and P. Harding
- Subjects
Nialamide ,Monoamine Oxidase Inhibitors ,Adolescent ,Statistics as Topic ,Pharmacology ,Toxicology ,Placebos ,Arts and Humanities (miscellaneous) ,Intellectual Disability ,Phenylketonurias ,medicine ,Amines ,Child ,Mental subnormality ,Psychological Tests ,business.industry ,Mental Disorders ,Rehabilitation ,Amine oxidase inhibitors ,Psychiatry and Mental health ,Neurology ,Neurology (clinical) ,Oxidoreductases ,business ,medicine.drug - Published
- 2008
- Full Text
- View/download PDF
44. Characterization ofPhytophthora cinnamomipopulations from ornamental plants in South Carolina, USA
- Author
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C.-H. Duan, M. B. Riley, and S. N. Jeffers
- Subjects
South carolina ,Mating type ,Sporangium ,fungi ,Biology ,Phytophthora cinnamomi ,biology.organism_classification ,Fungicide ,chemistry.chemical_compound ,chemistry ,Ornamental plant ,Botany ,Amplified fragment length polymorphism ,Agronomy and Crop Science ,Fatty acid methyl ester - Abstract
Fifty-one isolates of Phytophthora cinnamomi isolated from ornamental plants in South Carolina, USA, between 1995 and 2000 were characterized by sporangium morphology, mating type, sensitivity to the fungicide mefenoxam, fatty acid methyl ester (FAME) profile analysis, and amplified fragment length polymorphism (AFLP) analysis. Sporangium shapes were predominantly ovoid to ellipsoid, and size averaged 65.5×40.3 μm (length×breadth) with average length/breadth ratio of 1.6. Forty-nine isolates were the A2 mating type with only two A1 isolates found. This is the first report of the A1 mating type of P. cinnamomi in South Carolina. All isolates were sensitive to mefenoxam and EC50 values for all isolates were less than 0.2 μg ml−1. FAMEs of each isolate were analysed by gas chromatography and revealed five major fatty acids: myristic (14:0), palmitic (16:0), linoleic (18:2ω6c), oleic (18:1ω9c), and eicosapentaenoic (20:5ω3c) acids. These five fatty acids accounted for more than 80% of FAME profiles. ...
- Published
- 2008
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- View/download PDF
45. Maximize power efficiency and profitability through high voltage electric heating technology
- Author
-
Christopher Molnar and M. David Riley
- Subjects
Engineering ,business.industry ,Electrical engineering ,Thyristor ,High voltage ,Single-phase electric power ,Automotive engineering ,Hardware_GENERAL ,Electric heating ,Profitability index ,Voltage regulation ,business ,Low voltage ,Electrical efficiency - Abstract
Low voltage (below 1000V) electric heating equipment has limited the use of electric heating for petroleum and chemical operations due to high output and current draw. This paper introduces the benefits of high voltage (above 1000v) electric heat and high voltage (HV) thyristor control technology to enable alternative heating methods. The focus will be on the increase of power efficiency, the reduction in installation, maintenance, and operational costs, and the enablement of application methods.
- Published
- 2015
- Full Text
- View/download PDF
46. Persistence of collective behavior at high spin in theN=88nucleusTb153
- Author
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J. Simpson, E. S. Paul, M. A. Riley, T. Lauritsen, P. J. Nolan, D. C. Radford, J. P. Revill, J. Ollier, P. Hampson, J. M. Rees, R. V. F. Janssens, F. G. Kondev, U. Garg, Marina Petri, S. Zhu, Saul L. Miller, A. D. Ayangeakaa, Martin Carpenter, P. J. R. Mason, Ingemar Ragnarsson, J. T. Matta, D. J. Hartley, C. J. Chiara, Xuejun Wang, Calem Hoffman, and L. L. Riedinger
- Subjects
Physics ,Nuclear and High Energy Physics ,Collective behavior ,medicine.anatomical_structure ,Spins ,Excited state ,Yrast ,medicine ,Gammasphere ,Atomic physics ,Nucleus ,Line (formation) ,Spin-½ - Abstract
Excited states in the N = 88 nucleus Tb-153 were observed up to spin similar to 40 in an experiment utilizing the Gammasphere array. The Tb-153 states were populated in a weak alpha 4n evaporation channel of the Cl-37 + Sn-124 reaction. Two previously known sequences were extended to higher spins, and a new decoupled structure was identified. The pi h(11/2) band was observed in the spin region where other N = 88 isotopes exhibit effects of prolate to oblate shape changes leading to band termination along the yrast line, whereas Tb-153 displays a persistent collective behavior. However, minor perturbations of the very highest state in both signatures of this h(11/2) band are observed, which perhaps signal the start of the transition towards band termination. (Less)
- Published
- 2015
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47. High-spin terminating states in theN=88Ho155andEr156isotones
- Author
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R. V. F. Janssens, D. C. Radford, J. Ollier, J. P. Revill, D. J. Hartley, P. J. R. Mason, J. Simpson, J. T. Matta, C. J. Chiara, T. Lauritsen, Martin Carpenter, F. G. Kondev, Ingemar Ragnarsson, A. D. Ayangeakaa, E. S. Paul, P. J. Nolan, Xuejun Wang, P. Hampson, Saul L. Miller, S. Zhu, Jnaneswari Gellanki, J. M. Rees, Calem Hoffman, U. Garg, Marina Petri, and M. A. Riley
- Subjects
Physics ,Nuclear and High Energy Physics ,Normalization property ,medicine.anatomical_structure ,medicine ,Shell (structure) ,Atomic physics ,Spin (physics) ,Nucleus ,Excitation - Abstract
The Sn-124(Cl-37, 6n gamma) fusion-evaporation reaction at a bombarding energy of 180 MeV has been used to significantly extend the excitation level scheme of Ho-155(67)88. The collective rotational behavior of this nucleus breaks down above spin I similar to 30 and a fully aligned noncollective (band terminating) state has been identified at I-pi = 79/2(-). Comparison with cranked Nilsson-Strutinsky calculations also provides evidence for core-excited noncollective states at I-pi = 87/2(-) and (89/2(+)) involving particle-hole excitations across the Z = 64 shell gap. A similar core-excited state in Er-156(68)88 at I-pi = (46(+)) is also presented.
- Published
- 2015
- Full Text
- View/download PDF
48. Lactate and Aqueous Humour
- Author
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M. V. Riley
- Subjects
Chromatography ,Aqueous humour ,Chemistry - Published
- 2015
- Full Text
- View/download PDF
49. Observation ofγvibrations and alignments built on non-ground-state configurations inDy156
- Author
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D. Curien, N. Cooper, C. W. Beausang, David Miller, W. D. Kulp, S. Zhu, E. A. McCutchan, J. L. Wood, C.-H. Yu, F. G. Kondev, N. Redon, P. E. Garrett, J. M. Allmond, C. J. Chiara, R. V. F. Janssens, V. Werner, Judy M. Simpson, M. A. Riley, Xuan Wang, I. Stefanescu, D. J. Hartley, S. N. T. Majola, B. J. P. Gall, J. Piot, M. P. Carpenter, L. L. Riedinger, T. Lauritsen, and J.F. Sharpey-Schafer
- Subjects
Physics ,Nuclear and High Energy Physics ,Spins ,Yrast ,Pairing ,Nuclear Theory ,Gammasphere ,S band ,Atomic physics ,Nuclear Experiment ,Nucleon ,Spin (physics) ,Ground state - Abstract
The exact nature of the lowest Kπ=2+ rotational bands in all deformed nuclei remains obscure. Traditionally they are assumed to be collective vibrations of the nuclear shape in the γ degree of freedom perpendicular to the nuclear symmetry axis. Very few such γ bands have been traced past the usual backbending rotational alignments of high-j nucleons. We have investigated the structure of positive-parity bands in the N=90 nucleus Dy156, using the Nd148(C12,4n)Dy156 reaction at 65 MeV, observing the resulting γ-ray transitions with the Gammasphere array. The even- and odd-spin members of the Kπ=2+γ band are observed up to 32+ and 31+, respectively. This rotational band faithfully tracks the ground-state configuration to the highest spins. The members of a possible γ vibration built on the aligned yrast S band are observed up to spins 28+ and 27+. An even-spin positive-parity band, observed up to spin 24+, is a candidate for an aligned S band built on the seniority-zero configuration of the 0+2 state at 676 keV. The crossing of this band with the 0+2 band is at ℏωc=0.28(1)MeV and is consistent with the configuration of the 0+2 band not producing any blocking of the monopole pairing.
- Published
- 2015
- Full Text
- View/download PDF
50. Observation of states beyond band termination in156, 157, 158Er and strongly deformed structures in173, 174, 175Hf
- Author
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G. Mukherjee, R. A. Kaye, M. Danchev, P. Chowdhury, P. J. Nolan, R. M. Clark, J. Goon, T. Lauritsen, F. G. Kondev, P. T. W. Choy, M. A. Riley, Jing-ye Zhang, E. F. Moore, P. Fallon, D. B. Campbell, A. Pipidis, D. T. Joss, E. S. Paul, E. Ngijoi-Yogo, Martin Carpenter, B. McClain, Andreas Görgen, R. W. Laird, A. Aguilar, Daniel Ward, D. J. Hartley, Karin Lagergren, R. V. F. Janssens, Philip M Walker, G.D. Dracoulis, A. O. Evans, D. E. Appelbe, C. R. Bingham, M. K. Djongolov, Fikret Saric, G. Sletten, G. B. Hagemann, L. L. Riedinger, M. Cromaz, H. I. Park, T. L. Khoo, Ingemar Ragnarsson, D. M. Cullen, S. K. Tandel, A. O. Macchiavelli, and J. Simpson
- Subjects
Physics ,Angular momentum ,Particle properties ,Deformation (mechanics) ,Spectrometer ,chemistry.chemical_element ,Condensed Matter Physics ,Atomic and Molecular Physics, and Optics ,Erbium ,Superdeformation ,chemistry ,Gammasphere ,Atomic physics ,Spin (physics) ,Mathematical Physics - Abstract
High-spin terminating bands in heavy nuclei were first identified in nuclei around Er-158(90). While examples of terminating states have been identified in a number of erbium isotopes, almost nothing is known about the states lying beyond band termination. In the present work, the high-spin structure of Er-156,Er-157,Er-158 has been studied using the Gammasphere spectrometer. The subject of triaxial superdeformation and 'wobbling' modes in Lu nuclei has rightly attracted a great deal of attention. Very recently four strongly or superdeformed (SD) sequences have been observed in Hf-174, and cranking calculations using the Ultimate Cranker code predict that such structures may have significant triaxial deformation. We have performed two experiments in an attempt to verify the possible triaxial nature of these bands. A lifetime measurement was performed to confirm the large (and similar) deformation of the bands. In addition, a high-statistics, thin-target experiment took place to search for linking transitions between the SD bands, possible wobbling modes, and new SD band structures.
- Published
- 2006
- Full Text
- View/download PDF
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