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Background: Atypical presentations of ACS delay its recognition and treatment in the older adults. During hospitalization, depression and functional decline, which is unique to older adults, leads to poor clinical outcome. Steps taken for its prevention is unlikely to become a priority for the Cardiologist. This study was conducted to identify depression among older adults who developed ACS during hospitalization for noncardiac illness and their outcome. Methods: 310 older adults with ACS were included from 26 June 2020 to 13 October 2020. Subjects were divided into those admitted primarily due to an ACS (Group I, n = 94) and those developing ACS after admission for noncardiac illness (Group II, n = 216). Co morbidities, medications, investigations, management, clinical outcome, Geriatric Depression Scale was compared between the two groups at the time of admission, after 30 days and after 6 months. Results: Majority of them were admitted due to acute kidney injury (27.1%) in group II and had a non ST elevation ACS (90.2%). Optimum management was given to a lesser extent because of the clinical condition of these patients. Depression during hospitalization, during follow up and poor clinical, functional and cognitive outcome was more in group II. Conclusion: Optimum medical management was not given to considerable number of patients because of atypical presentations, clinical condition, along with functional and cognitive decline which resulted from depression. Clinicians must be vigilant for the development of depression when an older adult is admitted to the hospital, as early detection and optimum management provides better clinical outcome.

Background: Atypical presentations of acute coronary syndrome (ACS) delay its recognition and treatment in the elderly patients. Functional decline and delirium which are common to the elderly during hospitalization, leads to cognitive impairment and poor health outcomes. Steps taken for its prevention is usually not considered the top priority by the cardiologist. The present study was conducted to identify cognitive decline among elderly patients who developed ACS during hospitalization for noncardiac illness and their outcome. Materials and Methods: Three hundred and ten elderly patients above 60 years of age with ACS were included from June 26, 2020 to October 13, 2020. Subjects were divided into those admitted primarily due to an ACS (Group I, n = 94) and those developing ACS following admission for noncardiac illness (Group II, n = 216). Co-morbidities, medications, investigations, management, clinical outcome, and Montreal Cognitive Assessment scale were compared between the two groups at the time of admission, after 30 days and after 6 months. Results: Majority of the subjects were admitted due to acute kidney injury (27.1%) in Group II and had a non-ST elevation ACS (90.2%). Optimum management was given to a lesser extent due to the clinical condition of these patients. Poor clinical outcome, cognitive impairment during hospitalization and cognitive decline during follow-up was more in Group II. Conclusion: Clinicians must be vigilant for the development of cognitive impairment and cognitive decline when an elderly patient is admitted to the hospital, as early detection and optimum management provides better clinical and cognitive outcome.

Odontomas are benign developmental tumors formed by the improper growth of completely differentiated epithelial and mesenchymal cells of odontogenic origin. The etiology of odontoma is unknown and it is detected during routine radiographic examination. The ideal management is early detection and surgical enucleation. The commonly associated clinical problems of odontomas are delayed exfoliation of primary teeth, delayed eruption or impaction of permanent teeth, displacement of teeth, root resorption, congenital missing, and widening of follicular space. Here, we describe a unique case of compound odontoma with a high number of denticles managed based on a definite decision support system over 8 years. An 8-year-old boy with 70 denticles in the left maxillary region underwent enucleation. On periodic follow-up, the associated impacted lateral incisor was extruded orthodontically.

Background: Different studies in India have shown that more than 50% of elderly population of India are suffering from malnutrition and more than 90% have less than recommended intake. Objectives: The aim of this study is to estimate the prevalence and correlates of malnutrition among elderly aged 60 years and above in an urban area in Coimbatore using Mini Nutritional Assessment (MNA). Methods: A cross-sectional study was conducted on 154 households and 190 elderly were interviewed. Nutritional status was assessed using the MNA questionnaire. Results: Mean (standard deviation) age of the total population (n = 190) was 71.09 (7.93) years and 30% was male. In this population, 37 (19.47%) was malnourished (MNA

The prediction of who develops metastasis has been the most difficult aspect in the management of breast cancer patients. The lymph node metastasis has been the most useful predictor of prognosis and patient management. However, a good proportion of patients with lymph node positivity remain disease free for 5 years or more, while about a third of those who were lymph node negative develop distant metastasis within the same period. This warrants a robust biomarker(s), preferably gene expression based. In order to elucidate gene-based biomarkers for prognosis of breast cancers, gene expression profiling of primary tumors and follow-up for over 5 years has been performed. The analysis revealed a network of genes centered around the tripartite motif-containing protein 28 as an important indicator of disease progression. Short hairpin RNA–mediated knockdown of tripartite motif-containing protein 28 in breast cancer cells revealed a decreased expression of epithelial-to-mesenchymal transition markers and increased expression of epithelial markers, decreased migration and invasion, and increased chemosensitivity to doxorubicin, 5-fluorouracil, and methotrexate. Furthermore, knockdown of tripartite motif-containing protein 28 resulted in the decrease of stemness as revealed by sphere formation assay as well as decreased expression of CD44 and Bmi1. Moreover, tripartite motif-containing protein 28 knockdown significantly reduced the tumor size and lung metastasis in orthotopic tumor xenograft assay in immunocompromised mice. The tumor size was further reduced when these mice were treated with doxorubicin. These data provide evidence for tripartite motif-containing protein 28 as a biomarker and a potential therapeutic target for breast cancer.

In solar thermal applications, the performance of a solar absorber panel with a reflector is critical. In sense, different absorbers are used to enhance thermal efficiency. In addition to this, various coatings on solar absorber panels are introduced, and the performance of the same coated panels are examined with experimental study by design of experiment concept. For the reason, this work utilized the black-chrome coating (BC) and nickel-cobalt-coating (Ni-Co) on copper solar absorber panel. The reflectors were also used to maximize the incident solar radiation on the absorber. In this experiment the process variables are flow rate, collector angle, and reflector angle and the thermal efficiency of solar panel is the response. The response surface methodology with Box Behnken design is used to collect the experimental data from experimental setup. The collected data from designed experiment are analyzed by using Analysis of Variance Table (ANOVA). From this the coating on the absorber panel and reflectors are improved the thermal efficiency up to 89.3% of the Black – Chrome solar flat plate collector than Ni-Co panel.

Currently, electric cars are receiving a lot of attention because of their low fuel consumption and pollution-free nature. The efficiency of electric vehicles is constantly being improved via a variety of studies and applications. The battery is a significant portion of an electric vehicle’s overall component count. Because the electric vehicle’s battery acts like the vehicle’s heart, battery performance and efficiency in electric vehicles (EVs) are examined in this research.

In the present study, twenty-five banana cultivars (eight diploids and seventeen triploids) were screened for their male fertility status with reference to the pollen output per anther, pollen size and pollen viability. The results showed that the pollen output and pollen viability are higher in monospecific diploids than the cultivars having the genome of both Musa acuminata and Musa balbisiana. Pollen size were higher in triploids than the diploids. The cultivars such as ‘Rose’, ‘Hatidat’, ‘Athiakol’, ‘Bhimkol’ and ‘Popoulu’ were reported to be polleniferous similar to proven male fertile parents such as ‘Pisang Lilin’ or ‘Anaikomban’. The complexities arising out of ploidy status and genomic differences not only impact pollen viability but also pollen production.

Many research works are being carried out to enhance the performances of internal combustion engines to meet out the current energy demand and to reduce the emission with the alternate fuels. In this experimental investigation, the performances and emission characteristics of compression ignition engine were studied by using electronic fuel fumigation method. The lemongrass biodiesel blended with 20% of biodiesel and 80% of diesel (B20) was used as primary fuel and 1-propanol is used as secondary fuel for fumigation. The Kirlosker, single cylinder four stroke, direct injection, and water cooled engine was taken for conduction of tests. The speed of the engine is maintained constant and the engine load was varied in the range of 0%–100% and fumigation injection timing is varied in the range of 1 ms, 3 ms and 5 ms to study the engine parameters. It is studied that the brake thermal efficiency of fumigation fuel at 5 ms is 6.7% higher than diesel and at 3 ms is 3.1% higher than the diesel fuel at 100% load. The specific fuel consumption at 5 ms is 16 % higher than the reference diesel fuel. The 5 ms 1-propanol fumigation produces the maximum HC and CO with minimum smoke and NO because of lower combustion temperature and incomplete combustion. The SFC of fumigation fuel at 5 ms is 18.6% higher than diesel at 100% load and 23 % higher than diesel at 80% load. The net heat release of fumigation fuel (1-propanol) at 1 ms produces 2% higher than the reference diesel at crank angle of 360°. The fumigation fuel (1-propanol) injection timing at 5 ms produces more percentage of CO at different load conditions. It is also studied that the minimum level of CO is 0.38 % at 40% load condition. The fumigation fuel at 5 ms injection timing produces minimum percentage of CO2 at different load conditions. The minimum level of CO2 is 9.3% at 80% load condition. The other emissions are also analyzed and recorded the levels based on the load condition.