1. Helicobacter pylori in a Chukotka Native male population
- Author
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O V, Reshetnikov, Y P, Nikitin, M V, Kholmogortsev, S A, Kurilovich, and O A, Pycllik
- Subjects
Adult ,Male ,Rural Population ,Helicobacter pylori ,Data Collection ,Incidence ,Middle Aged ,Helicobacter Infections ,Russia ,Gastric Mucosa ,Inuit ,Risk Factors ,Gastritis ,Gastroscopy ,Humans - Abstract
Helicobacter pylori (HP) is a widespread human pathogen closely associated with gastroduodenal diseases. Thirty-four males from one of the settlements of coastal Chukotka (72% of total adult male population, mean age 31.6 years) underwent upper endoscopy, and HP was examined histologically in antral biopsies (Giemsa stain). Histology revealed normal mucosa in 16%, antral superficial gastritis in 29%, and atrophic gastritis in 55%. HP was found in 40% of histological specimens of normal mucosa, in 100% of superficial gastritis, and in 77% of atrophic gastritis. Correlation was found between the degree of bacterial contamination and both the activity of gastritis and grade of mononuclear infiltration. Data indicate a high prevalence of HP among Chukotka Natives (77%) which may partly explain the significant frequency of antral gastritis in this population.
- Published
- 1999