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Sentiment analysis is the contextual analysis of words to retrieve the social opinion of a brand which aids the business firms/institutions to know the impact of their products/services. It is habitual that users may express different opinions regarding various aspects of the same entity. Therefore, there is a strong demand to extract all the opinion targets may those be explicitly mentioned aspects or implicit aspects which are not directly specified in the reviews. In this context, comparatively less amount of work has been carried out concerning implicit aspect detection. The proposed work has been dedicated solely to extracting the implicit aspects using a dynamic approach based on the type of sentence containing the clues for implicit aspect. A novel aspect pointer compendium (APC) has been developed that catalyzes the task of finding implicit aspects to the maximum extent possible. The APC incorporates the usage of different types of clues such as synonym clues, context clues, phrase clues, and partially implicit aspects that aid in the detection of hidden aspects. Based on this idea, the proposed work classifies the implicit aspect sentences into six types and proceeds with the task in an efficient manner. To strengthen the task of implicit aspect detection, the proposed work utilizes a hybrid technique encompassing APC, domain-specific adjective-noun collocation list (DSANCL), and the explicit aspect-opinion word pairs extracted from the reviews. The experimentation and results reveal that the proposed hybrid approach shows a good improvement in terms of the efficacy of extracting the implicit aspects as compared to the existing baseline models.

The role of solar activity in the growth of an earthquake (EQ) is the topic of study here, focussing on the correlation & distribution function between global EQ events of M ≥ 4.5 and solar parameters covering seven cycles from 18 to 24. The analysis modes are in two steps: (i) EQ events in a total of all cycles taken under study and solar role on their growth; and (ii) EQ events filtered for a High Solar Active (HSA) and a Low Solar Active (LSA) years for each individual cycle & the respective contribution of solar strength to their occurrences. The paper presents the observation by drawing a relation between EQ event ratio during LSA and HSA year, i.e., EQLSA/EQHSA with the corresponding Rz ratio of the years, an approach adopted to reduce any bias/errors that arise on availability of more EQ data as year advances. The analysis offers a negative cum complex distribution with more EQ cases at 60–70% below the peak Rz when strong solar ambiances are observed to inhibit the growth of severe EQ events. The overall correlation analyses between Rz, geomagnetic indices like Kp/DST, and EQ-events of different magnitudes also provided a conclusion that solar ambiances play a complicated role in the growth process of an EQ. These observations are discussed by invoking the Forbush effect along with the possible contribution of atmospheric variabilities like global temperature, lithosphere heat content, and anthropogenic components.

Disease and disorders are outlined as disablement of the normal state of living organism and annoyance of normal functioning of the body respectively. The ideal causes of the disorders are genetic factors, disease, stress or trauma. Genetic disorders are a pathological state provoked by one or more monstrosities in the genome. Spinal Muscular Atrophy is a rare genetic disease and most common monogenic cause of infant mortality. Hypotonia and weakness are most common manifestations of Spinal Muscular Atrophy delineated by degeneration of anterior horn cells of the spinal cord. SMA is originated due to mutations and deletions of SMN1 (Survival Motor Neuron) gene on Chromosome 5q. Disease modifying therapy and Gene replacing therapy are the common gene therapy used to treat genetic disorders. Zolgensma is an Adeno virus associated gene therapy restored a gene which is functional one. Children under the age of 2 are benefited from a single time intravenous (IV) infusion of Zolgensma. In future Gene therapy can treat all the illness associated with Genetic disorders.

Nurse preceptors are key stakeholders in providing quality clinical education. This study aimed to explore the perspectives of nurse preceptors on a web-based clinical pedagogy program and clinical teaching. A descriptive qualitative design was adopted. The program was made accessible to the nurse preceptors who were assigned nursing students from July 2019 to June 2020. Upon completion of clinical teaching, a total of 19 nurse preceptors participated in four focus group discussions. The discussions were audio recorded and transcribed verbatim, and thematic analysis was conducted. Five themes, with 11 subthemes, emerged: (i) Undergoing the process of self-awareness and development; (ii) Mastering newly acquired skills to refine own teaching approach; (iii) Implementing consistent evaluation and constructive feedback; (iv) Dual roles and responsibilities of preceptor; and (v) Benefits and barriers of the program. This study highlighted the knowledge and skills preceptors gained through the program which gave them newfound confidence and facilitated their clinical teaching and evaluation. As the shift towards online learning progresses, web-based learning can be a useful platform for professional development of nurse preceptors.

Candlenut has a lot of potential pharmacological benefits including in hair care, in treating skin problems such as psoriasis, and in its use as an emollient. However, the high unsaturated fatty acid content of candlenut oil causes it to be easily degraded by oxidation due to exposure to air, light, and humidity. Nanoencapsulations were found to be an alternative in protecting the materials from degradation. The purpose of this study was to investigate the effect of polymer-based nanoencapsulations on the oxidative stability of candlenut oil. Polyvinyl alcohol (PVA) was used as a polymer wall material. A lower peroxide value indicates better oil stability against oxidation. Results showed that nano-encapsulated candlenut oil has a significantly lower average peroxide value of 0.41 meq/100g over 35 days storage time, compared to 3.8 meq/100g in pure candlenut oil. Furthermore, based on its physical characterization, it was found that the reduction of particle size with the optimal size of 172±12 nm was achieved by increasing the amount of PVA. A well-chosen and well-calculated amount of polymer material, therefore, plays an important role to obtain optimal nano-encapsulated candlenut oil. Keywords: nanoencapsulation, candlenut oil, oxidative stability, polymeric materials

It has recently become a matter of discussion whether it is correct to use regional tree-ring chronologies in spatiotemporal climate reconstructions, since natural and climatic conditions in the regions may be heterogeneous, varying on different scales (from micro to global). We have studied the response of tree-ring width to climate in Scots pine (Pinus sylvestris L.) growing in the steppe zone, in insular pine forest of the Southern Urals and ribbon pine forests of Altai. Regional features and differences between the corresponding tree-ring chronologies obtained in the season of tree-ring formation (May–July) and spatiotemporal asynchrony in the long-term dynamics of tree-ring width in the study regions have been revealed.

This paper examines the sensitivity training provided to the employees which makes them discuss openly and interpersonal skills are developed. Sensitivity training has been conducted frequently in the organization and the employees are satisfied with the quality of training which has helped to increase the overall efficiency of the organization. If sensitivity training is not conducted properly, the problems frequently faced in an organization are lack of understanding, lack of communication, and an increase in conflict. Incorporating evidence from reviews, surveys, and personal contact, this study aims to determine the impact of sensitivity training provided to employees. Based on a review of the literature on sensitivity training, the objectives and questionnaires have been framed and distributed to the employees who have attended sensitivity training for primary data collection. This study is descriptive in nature. The type of Sampling used in this study is stratified sampling using a structured questionnaire as a research instrument. The total population of the company is 120 employees of which 50 employees of various departments have responded. The same 50 respondents have been taken as a sample size for this project. The data collected were analyzed using SPSS. The findings are positive when sensitivity training is conducted. The employees agreed that the training was helpful, interactive, engaging, supportive, understanding about the issues, and satisfied with the quality of the training. Suggestions given by the trainee have been taken into consideration. Employees also agreed that they felt confident at the end of the sensitivity training. &nbsp

The application of QSAR along with other in silico tools like molecular docking, and molecular dynamics provide a lot of promise for finding new treatments for life-threatening diseases like Type 2 diabetes mellitus (T2DM). The present study is an attempt to develop Monte Carlo algorithm-based QSAR models using freely available CORAL software. The experimental data on the α-amylase inhibition by a series of benzothiazole-linked hydrazone/2,5-disubstituted-1,3,4-oxadiazole hybrids were selected as endpoint for the model generation. Initially, a total of eight QSAR models were built using correlation intensity index (CII) as a criterion of predictive potential. The model developed from split 6 using CII was the most reliable because of the highest numerical value of the determination coefficient of the validation set (

Introduction and Aim: Non-alcoholic fatty liver disease (NAFLD) is one of the common causes of liver cirrhosis among general population.Studieshave identified NAFLD and evaluated lipid profile in pregnant women. Some have explored association that existed between lipid levels and adverse pregnancy outcome in western countries. Our aim was to find the prevalence of non-alcoholic fatty liver disease (NAFLD) in pregnant women among rural population in their III trimester and to assess dyslipidemia in these women. Materials and Methods: This is a prospective study conducted on 101 rural pregnant women coming for antenatal visits in their third trimester to Dept.,of Obstetrics and Gynaecology,PESIMSR, Kuppam.Liver scan was done during the regular obstetric scan to identify NAFLD. All pregnant women underwent lipid profile testing (Triglyceride,Total Cholesterol, HDL,LDL,VLDL). Results: There was a 1% prevalence of NAFLD among 101 rural expectant mothers.Lipid profile significantly (p