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1. Palliativmedizinische Aspekte in der klinischen Akut- und Notfallmedizin sowie Intensivmedizin: Konsensuspapier der DGIIN, DGK, DGP, DGHO, DGfN, DGNI, DGG, DGAI, DGINA und DG Palliativmedizin

Author

Michels, Guido, John, Stefan, Janssens, Uwe, Raake, Philip, Schütt, Katharina Andrea, Bauersachs, Johann, Barchfeld, Thomas, Schucher, Bernd, Delis, Sandra, Karpf-Wissel, Rüdiger, Kochanek, Matthias, von Bonin, Simone, Erley, Christiane M., Kuhlmann, Susanne D., Müllges, Wolfgang, Gahn, Georg, Heppner, Hans Jürgen, Wiese, Christoph H. R., Kluge, Stefan, Busch, Hans-Jörg, Bausewein, Claudia, Schallenburger, Manuela, Pin, Martin, and Neukirchen, Martin

Published
2023
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2. Palliativmedizinische Aspekte in der klinischen Akut- und Notfallmedizin sowie Intensivmedizin: Konsensuspapier der DGIIN, DGK, DGP, DGHO, DGfN, DGNI, DGG, DGAI, DGINA und DGPalliativmedizin

Author

Michels, Guido, John, Stefan, Janssens, Uwe, Raake, Philip, Schütt, Katharina Andrea, Bauersachs, Johann, Barchfeld, Thomas, Schucher, Bernd, Delis, Sandra, Karpf-Wissel, Rüdiger, Kochanek, Matthias, von Bonin, Simone, Erley, Christiane M., Kuhlmann, Susanne D., Müllges, Wolfgang, Gahn, Georg, Heppner, Hans Jürgen, Wiese, Christoph H. R., Kluge, Stefan, Busch, Hans-Jörg, Bausewein, Claudia, Schallenburger, Manuela, Pin, Martin, and Neukirchen, Martin

Published
2023
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7. Palliative aspects in clinical acute and emergency medicine as well as intensive care medicine

Author

Michels, Guido, primary, John, Stefan, additional, Janssens, Uwe, additional, Raake, Philip, additional, Schütt, Katharina Andrea, additional, Bauersachs, Johann, additional, Barchfeld, Thomas, additional, Schucher, Bernd, additional, Delis, Sandra, additional, Karpf-Wissel, Rüdiger, additional, Kochanek, Matthias, additional, von Bonin, Simone, additional, Erley, Christiane M., additional, Kuhlmann, Susanne D., additional, Müllges, Wolfgang, additional, Gahn, Georg, additional, Heppner, Hans Jürgen, additional, Wiese, Christoph H. R., additional, Kluge, Stefan, additional, Busch, Hans-Jörg, additional, Bausewein, Claudia, additional, Schallenburger, Manuela, additional, Pin, Martin, additional, and Neukirchen, Martin, additional

Published
2023
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10. Characteristics in Non–Vitamin K Antagonist Oral Anticoagulant–Related Intracerebral Hemorrhage

Author

Gerner, Stefan T., Kuramatsu, Joji B., Sembill, Jochen A., Sprügel, Maximilian I., Hagen, Manuel, Knappe, Ruben U., Endres, Matthias, Haeusler, Karl Georg, Sobesky, Jan, Schurig, Johannes, Zweynert, Sarah, Bauer, Miriam, Vajkoczy, Peter, Ringleb, Peter A., Purrucker, Jan C., Rizos, Timolaos, Volkmann, Jens, Müllges, Wolfgang, Kraft, Peter, Schubert, Anna-Lena, Erbguth, Frank, Nueckel, Martin, Schellinger, Peter D., Glahn, Jörg, Knappe, Ulrich J., Fink, Gereon R., Dohmen, Christian, Stetefeld, Henning, Fisse, Anna Lena, Minnerup, Jens, Hagemann, Georg, Rakers, Florian, Reichmann, Heinz, Schneider, Hauke, Rahmig, Jan, Ludolph, Albert Christian, Stösser, Sebastian, Neugebauer, Hermann, Röther, Joachim, Michels, Peter, Schwarz, Michael, Reimann, Gernot, Bäzner, Hansjörg, Schwert, Henning, Claßen, Joseph, Michalski, Dominik, Grau, Armin, Palm, Frederick, Urbanek, Christian, Wöhrle, Johannes C., Alshammari, Fahid, Horn, Markus, Bahner, Dirk, Witte, Otto W., Günther, Albrecht, Hamann, Gerhard F., Engelhorn, Tobias, Lücking, Hannes, Dörfler, Arnd, Schwab, Stefan, and Huttner, Hagen B.

Published
2019
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11. Neuromuskuläre Erkrankungen

Author

Müllges, Wolfgang, Gold, Ralf, Hansen, Hans-Christian, Anetseder, Martin, Metterlein, Thomas, Müller, Clemens R., Hund, Ernst, Winterholler, Martin, Schwab, Stefan, editor, Schellinger, Peter, editor, Werner, Christian, editor, Unterberg, Andreas, editor, and Hacke, Werner, editor

Published
2015
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14. 15 .Spätfolgen, Sekundärerkrankungen

Author

Willenberg, Holger S., primary, Knauerhase, Andreas, additional, Schomacher, Markus, additional, Helden, Andrea von, additional, Moskopp, Dag, additional, Henker, Christian, additional, Piek, Jürgen, additional, Müllges, Wolfgang, additional, and Runge, Uwe, additional

Published
2018
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16. Adressen

Author

Kraft, Peter, primary, Kraus, Martin, additional, Müllges, Wolfgang, additional, Weilbach, Franz, additional, and Westermaier, Thomas, additional

Published
2018
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17. Recommendations on palliative care aspects in intensive care medicine.

Author

Michels, Guido, Schallenburger, Manuela, Neukirchen, Martin, ICU Palliative Study Group, John, Stefan, Janssens, Uwe, Raake, Philip, Schütt, Katharina Andrea, Bauersachs, Johann, Barchfeld, Thomas, Schucher, Bernd, Delis, Sandra, Karpf-Wissel, Rüdiger, Kochanek, Matthias, von Bonin, Simone, Erley, Christiane M., Kuhlmann, Susanne D., Müllges, Wolfgang, Gahn, Georg, and Heppner, Hans Jürgen

Abstract

Background: The timely integration of palliative care is important for patients suffering from various advanced diseases with limited prognosis. While a German S-3-guideline on palliative care exists for patients with incurable cancer, a recommendation for non-oncological patients and especially for integration of palliative care into intensive care medicine is missing to date. Method: Ten German medical societies worked on recommendations on palliative care aspects in intensive care in a consensus process from 2018 to 2023. Results: Based on the german consensus paper, the palliative care aspects of the respective medical disciplines concerning intensive care are addressed. The recommendations partly refer to general situations, but also to specific aspects or diseases, such as geriatric issues, heart or lung diseases, encephalopathies and delirium, terminal renal diseases, oncological diseases and palliative emergencies in intensive care medicine. Measures such as non-invasive ventilation for symptom control and compassionate weaning are also included. Conclusion: The timely integration of palliative care into intensive care medicine aims to improve quality of life and symptom control and also takes into acccount the often urgently needed support for patients' highly stressed relatives. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Palliativmedizinische Aspekte in der klinischen Akut- und Notfallmedizin sowie Intensivmedizin: Konsensuspapier der DGIIN, DGK, DGP, DGHO, DGfN, DGNI, DGG, DGAI, DGINA und DGPalliativmedizin 1, 2.

Author

Michels, Guido, John, Stefan, Janssens, Uwe, Raake, Philip, Schütt, Katharina Andrea, Bauersachs, Johann, Barchfeld, Thomas, Schucher, Bernd, Delis, Sandra, Karpf-Wissel, Rüdiger, Kochanek, Matthias, von Bonin, Simone, Erley, Christiane M., Kuhlmann, Susanne D., Müllges, Wolfgang, Gahn, Georg, Heppner, Hans Jürgen, Wiese, Christoph H. R., Kluge, Stefan, and Busch, Hans-Jörg

Published
2023
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20. Neurodiagnostik in der Intensivmedizin

Author

Dörfler, Arnd, Forsting, Michael, Müllges, Wolfgang, Partik, Bernhard, Prayer, Daniela, Wildemann, Brigitte, Burchardi, H., editor, Larsen, R., editor, Marx, G., editor, Muhl, E., editor, and Schölmerich, J., editor

Published
2011
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22. Association of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis

Author

Kuramatsu, Joji B., primary, Gerner, Stefan T., additional, Ziai, Wendy, additional, Bardutzky, Jürgen, additional, Sembill, Jochen A., additional, Sprügel, Maximilian I., additional, Mrochen, Anne, additional, Kölbl, Kathrin, additional, Ram, Malathi, additional, Avadhani, Radhika, additional, Falcone, Guido J., additional, Selim, Magdy H., additional, Lioutas, Vasileios-Arsenios, additional, Endres, Matthias, additional, Zweynert, Sarah, additional, Vajkoczy, Peter, additional, Ringleb, Peter A., additional, Purrucker, Jan C., additional, Volkmann, Jens, additional, Neugebauer, Hermann, additional, Erbguth, Frank, additional, Schellinger, Peter D., additional, Knappe, Ulrich J., additional, Fink, Gereon R., additional, Dohmen, Christian, additional, Minnerup, Jens, additional, Reichmann, Heinz, additional, Schneider, Hauke, additional, Röther, Joachim, additional, Reimann, Gernot, additional, Schwarz, Michael, additional, Bäzner, Hansjörg, additional, Claßen, Joseph, additional, Michalski, Dominik, additional, Witte, Otto W., additional, Günther, Albrecht, additional, Hamann, Gerhard F., additional, Lücking, Hannes, additional, Dörfler, Arnd, additional, Ishfaq, Muhammad Fawad, additional, Chang, Jason J., additional, Testai, Fernando D., additional, Woo, Daniel, additional, Alexandrov, Andrei V., additional, Staykov, Dimitre, additional, Goyal, Nitin, additional, Tsivgoulis, Georgios, additional, Sheth, Kevin N., additional, Awad, Issam A., additional, Schwab, Stefan, additional, Hanley, Daniel F., additional, Huttner, Hagen B., additional, Sansing, Lauren, additional, Matouk, Charles C., additional, Leasure, Audrey, additional, Sobesky, Jan, additional, Bauer, Miriam, additional, Schurig, Johannes, additional, Rizos, Timolaos, additional, Haeusler, Karl Georg, additional, Müllges, Wolfgang, additional, Kraft, Peter, additional, Schubert, Anna-Lena, additional, Stösser, Sebastian, additional, Ludolph, Albert Christian, additional, Nueckel, Martin, additional, Glahn, Jörg, additional, Stetefeld, Henning, additional, Rahmig, Jan, additional, Fisse, Anna Lena, additional, Michels, Peter, additional, Schwert, Henning, additional, Hagemann, Georg, additional, Rakers, Florian, additional, Wöhrle, Johannes C., additional, Alshammari, Fahid, additional, Horn, Markus, additional, Bahner, Dirk, additional, Urbanek, Christian, additional, Palm, Frederick, additional, and Grau, Armin, additional

Published
2022
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23. Association of prothrombin complex concentrate administration and hematoma enlargement in non–vitamin K antagonist oral anticoagulant–related intracerebral hemorrhage

Author

Gerner, Stefan T., Kuramatsu, Joji B., Sembill, Jochen A., Sprügel, Maximilian I., Endres, Matthias, Haeusler, Karl Georg, Vajkoczy, Peter, Ringleb, Peter A., Purrucker, Jan, Rizos, Timolaos, Erbguth, Frank, Schellinger, Peter D., Fink, Gereon R., Stetefeld, Henning, Schneider, Hauke, Neugebauer, Hermann, Röther, Joachim, Claßen, Joseph, Michalski, Dominik, Dörfler, Arnd, Schwab, Stefan, Huttner, Hagen B., Horn, Markus, Bahner, Dirk, Hagemann, Georg, Rakers, Florian, Endres, Matthias, Haeusler, Karl Georg, Sobesky, Jan, Schurig, Johannes, Zweynert, Sarah, Bauer, Miriam, Vajkoczy, Peter, Fink, Gereon R., Dohmen, Christian, Stetefeld, Henning, Schwarz, Michael, Reimann, Gernot, Reichmann, Heinz, Schneider, Hauke, Rahmig, Jan, Gerner, Stefan T., Kuramatsu, Joji B., Bogenreuther, Christina, Sembill, Jochen A., Sprügel, Maximilian I., Hagen, Manuel, Knappe, Ruben, Köhrmann, Martin, Schwab, Stefan, Huttner, Hagen B., Kloska, Stephan P., Dörfler, Arnd, Ringwald, Jürgen, Hamann, Gerhard F., Röther, Joachim, Michels, Peter, Ringleb, Peter A., Purrucker, Jan, Rizos, Timolaos, Witte, Otto W., Günther, Albrecht, Wöhrle, Johannes C., Alshammari, Fahid, Claßen, Joseph, Michalski, Dominik, Grau, Armin, Palm, Frederick, Urbanek, Christian, Schellinger, Peter D., Glahn, Jörg, Knappe, Ulrich J., Wiendl, Heinz, Fisse, Anna Lena, Minnerup, Jens, Erbguth, Frank, Nueckel, Martin, Bäzner, Hansjörg, Schwert, Henning, Ludolph, Albert Christian, Stösser, Sebastian, Neugebauer, Hermann, Volkmann, Jens, Müllges, Wolfgang, Kraft, Peter, and Schubert, Anna‐Lena

Published
2018
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24. Association of intraventricular fibrinolysis with clinical outcomes in intracerebral hemorrhage: an individual participant data meta-analysis

Author

Kuramatsu, Joji B, Gerner, Stefan T, Falcone, Guido J, Selim, Magdy H, Lioutas, Vasileios-Arsenios, Endres, Matthias, Zweynert, Sarah, Vajkoczy, Peter, Ringleb, Peter A, Purrucker, Jan C, Volkmann, Jens, Neugebauer, Hermann, Ziai, Wendy, Erbguth, Frank, Schellinger, Peter D, Knappe, Ulrich J, Fink, Gereon R, Dohmen, Christian, Minnerup, Jens, Reichmann, Heinz, Schneider, Hauke, Röther, Joachim, Reimann, Gernot, Bardutzky, Jürgen, Schwarz, Michael, Bäzner, Hansjörg, Claßen, Joseph, Michalski, Dominik, Witte, Otto W, Günther, Albrecht, Hamann, Gerhard F, Lücking, Hannes, Dörfler, Arnd, Ishfaq, Muhammad Fawad, Sembill, Jochen A, Chang, Jason J, Testai, Fernando D, Woo, Daniel, Alexandrov, Andrei V, Staykov, Dimitre, Goyal, Nitin, Tsivgoulis, Georgios, Sheth, Kevin N, Awad, Issam A, Schwab, Stefan, Sprügel, Maximilian I, Hanley, Daniel F, Huttner, Hagen B, Collaborators, Sansing, Lauren, Matouk, Charles C, Leasure, Audrey, Sobesky, Jan, Bauer, Miriam, Schurig, Johannes, Rizos, Timolaos, Mrochen, Anne, Haeusler, Karl Georg, Müllges, Wolfgang, Kraft, Peter, Schubert, Anna-Lena, Stösser, Sebastian, Ludolph, Albert, Nueckel, Martin, Glahn, Jörg, Stetefeld, Henning, Rahmig, Jan, Kölbl, Kathrin, Fisse, Anna Lena, Michels, Peter, Schwert, Henning, Hagemann, Georg, Rakers, Florian, Wöhrle, Johannes C, Alshammari, Fahid, Horn, Markus, Bahner, Dirk, Urbanek, Christian, Ram, Malathi, Palm, Frederick, Grau, Armin, and Avadhani, Radhika

Subjects
Advanced and Specialized Nursing, drug therapy [Cerebral Hemorrhage], Fibrinolysis, diagnostic imaging [Cerebral Hemorrhage], intracerebral hemorrhage, mortality, Observational Studies as Topic, Treatment Outcome, Fibrinolytic Agents, standard of care, Drainage, Humans, Neurology (clinical), methods [Drainage], ddc:610, Cardiology and Cardiovascular Medicine, hydrocephalus, Cerebral Hemorrhage, Hydrocephalus
Abstract

Background: In patients with intracerebral hemorrhage (ICH), the presence of intraventricular hemorrhage constitutes a promising therapeutic target. Intraventricular fibrinolysis (IVF) reduces mortality, yet impact on functional disability remains unclear. Thus, we aimed to determine the influence of IVF on functional outcomes. Methods: This individual participant data meta-analysis pooled 1501 patients from 2 randomized trials and 7 observational studies enrolled during 2004 to 2015. We compared IVF versus standard of care (including placebo) in patients treated with external ventricular drainage due to acute hydrocephalus caused by ICH with intraventricular hemorrhage. The primary outcome was functional disability evaluated by the modified Rankin Scale (mRS; range: 0–6, lower scores indicating less disability) at 6 months, dichotomized into mRS score: 0 to 3 versus mRS: 4 to 6. Secondary outcomes included ordinal-shift analysis, all-cause mortality, and intracranial adverse events. Confounding and bias were adjusted by random effects and doubly robust models to calculate odds ratios and absolute treatment effects (ATE). Results: Comparing treatment of 596 with IVF to 905 with standard of care resulted in an ATE to achieve the primary outcome of 9.3% (95% CI, 4.4–14.1). IVF treatment showed a significant shift towards improved outcome across the entire range of mRS estimates, common odds ratio, 1.75 (95% CI, 1.39–2.17), reduced mortality, odds ratio, 0.47 (95% CI, 0.35–0.64), without increased adverse events, absolute difference, 1.0% (95% CI, −2.7 to 4.8). Exploratory analyses provided that early IVF treatment (≤48 hours) after symptom onset was associated with an ATE, 15.2% (95% CI, 8.6–21.8) to achieve the primary outcome. Conclusions: As compared to standard of care, the administration of IVF in patients with acute hydrocephalus caused by intracerebral and intraventricular hemorrhage was significantly associated with improved functional outcome at 6 months. The treatment effect was linked to an early time window

Published
2022

26. Acute Muscular Weakness

Author

Müllges, Wolfgang, Toyka, Klaus V., Hartung, Hans-Peter, Hanley, Daniel F., Hacke, Werner, editor, Hanley, Daniel F., editor, Einhäupl, Karl M., editor, Bleck, Thomas P., editor, Diringer, Michael N., editor, and Ropper, Allan H., editor

Published
1994
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27. Anticoagulant Reversal, Blood Pressure Levels, and Anticoagulant Resumption in Patients With Anticoagulation-Related Intracerebral Hemorrhage

Author

Kuramatsu, Joji B., Gerner, Stefan T., Schellinger, Peter D., Glahn, Jörg, Endres, Matthias, Sobesky, Jan, Flechsenhar, Julia, Neugebauer, Hermann, Jüttler, Eric, Grau, Armin, Palm, Frederick, Röther, Joachim, Michels, Peter, Hamann, Gerhard F., Hüwel, Joachim, Hagemann, Georg, Barber, Beatrice, Terborg, Christoph, Trostdorf, Frank, Bäzner, Hansjörg, Roth, Aletta, Wöhrle, Johannes, Keller, Moritz, Schwarz, Michael, Reimann, Gernot, Volkmann, Jens, Müllges, Wolfgang, Kraft, Peter, Classen, Joseph, Hobohm, Carsten, Horn, Markus, Milewski, Angelika, Reichmann, Heinz, Schneider, Hauke, Schimmel, Eik, Fink, Gereon R., Dohmen, Christian, Stetefeld, Henning, Witte, Otto, Günther, Albrecht, Neumann-Haefelin, Tobias, Racs, Andras E., Nueckel, Martin, Erbguth, Frank, Kloska, Stephan P., Dörfler, Arnd, Köhrmann, Martin, Schwab, Stefan, and Huttner, Hagen B.

Published
2015
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28. COVID-19 and intracranial hemorrhage: a multicenter case series, systematic review and pooled analysis

Author

Schmidbauer, Moritz L, primary, Ferse, Caroline, additional, Salih, Farid, additional, Klingner, Carsten, additional, Musleh, Rita, additional, Kunst, Stefan, additional, Wittstock, Matthias, additional, Neumann, Bernhard, additional, Bösel, Julian, additional, Godau, Jana, additional, Lochner, Piergiorgio, additional, Adam, Elisabeth H, additional, Jahnke, Kolja, additional, Knier, Benjamin, additional, Schirotzek, Ingo, additional, Müllges, Wolfgang, additional, Notz, Quirin, additional, Dengl, Markus, additional, Güldner, Andreas, additional, Onur, Oezguer A, additional, Borrega, Jorge Garcia, additional, Dimitriadis, Konstantinos, additional, and Günther, Albrecht, additional

Published
2021
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33. Progression of cerebral infarction before and after thrombectomy is modified by prehospital pathways.

Author

Kollikowski, Alexander M., Cattus, Franziska, Haag, Julia, Feick, Jörn, März, Alexander G., Weidner, Franziska, Schuhmann, Michael K., Müllges, Wolfgang, Stoll, Guido, Pham, Mirko, and Strinitz, Marc

Subjects
DISEASE progression, SCIENTIFIC observation, CEREBRAL infarction, PREOPERATIVE period, MULTIPLE regression analysis, SURGERY, PATIENTS, ACQUISITION of data, RETROSPECTIVE studies, MEDICAL protocols, THROMBECTOMY, POSTOPERATIVE period, STROKE patients, MEDICAL records, DESCRIPTIVE statistics, COMPUTED tomography, EMERGENCY medicine
Abstract

Background Evidence of the consequences of different prehospital pathways before mechanical thrombectomy (MT) in large vessel occlusion stroke is inconclusive. The aim of this study was to investigate the infarct extent and progression before and after MT in directly admitted (mothership) versus transferred (drip and ship) patients using the Alberta Stroke Program Early CT Score (ASPECTS). Methods ASPECTS of 535 consecutive large vessel occlusion stroke patients eligible for MT between 2015 to 2019 were retrospectively analyzed for differences in the extent of baseline, post-referral, and postrecanalization infarction between the mothership and drip and ship pathways. Time intervals and transport distances of both pathways were analyzed. Multiple linear regression was used to examine the association between infarct progression (baseline to postrecanalization ASPECTS decline), patient characteristics, and logistic key figures. results ASPECTS declined during transfer (9 (8-10) vs 7 (6-9), p<0.0001), resulting in lower ASPECTS at stroke center presentation (mothership 9 (7-10) vs drip and ship 7 (6-9), p<0.0001) and on follow-up imaging (mothership 7 (4-8) vs drip and ship 6 (3-7), p=0.001) compared with mothership patients. Infarct progression was significantly higher in transferred patients (points lost, mothership 2 (0-3) vs drip and ship 3 (2-6), p<0.0001). After multivariable adjustment, only interfacility transfer, preinterventional clinical stroke severity, the degree of angiographic recanalization, and the duration of the thrombectomy procedure remained predictors of infarct progression (R²=0.209, p<0.0001). Conclusions Infarct progression and postinterventional infarct extent, as assessed by ASPECTS, varied between the drip and ship and mothership pathway, leading to more pronounced infarction in transferred patients. ASPECTS may serve as a radiological measure to monitor the benefit or harm of different prehospital pathways for MT. [ABSTRACT FROM AUTHOR]

Published
2022
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34. Temporal changes in total and hippocampal brain volume and cognitive function in patients with chronic heart failure—the COGNITION.MATTERS-HF cohort study

Author

Frey, Anna, primary, Homola, György A, additional, Henneges, Carsten, additional, Mühlbauer, Larissa, additional, Sell, Roxane, additional, Kraft, Peter, additional, Franke, Maximilian, additional, Morbach, Caroline, additional, Vogt, Marius, additional, Müllges, Wolfgang, additional, Ertl, Georg, additional, Solymosi, László, additional, Pirpamer, Lukas, additional, Schmidt, Reinhold, additional, Pham, Mirko, additional, Störk, Stefan, additional, and Stoll, Guido, additional

Published
2021
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39. Neurodiagnostik in der Intensivmedizin

Author

Dörfler, Arnd, primary, Forsting, Michael, additional, Müllges, Wolfgang, additional, Partik, Bernhard, additional, Prayer, Daniela, additional, and Wildemann, Brigitte, additional

Published
2011
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41. Antagonizing dabigatran by idarucizumab in cases of ischemic stroke or intracranial hemorrhage in Germany—Updated series of 120 cases

Author

Kermer, Pawel, primary, Eschenfelder, Christoph C, additional, Diener, Hans-Christoph, additional, Grond, Martin, additional, Abdalla, Yasser, additional, Abraham, Alexej, additional, Althaus, Katharina, additional, Becks, Gebhard, additional, Berrouschot, Jörg, additional, Berthel, Jörg, additional, Bode, Felix J., additional, Burghaus, Lothar, additional, Cangür, Hakan, additional, Daffertshofer, Michael, additional, Edelbusch, Sebastian, additional, Eggers, Jürgen, additional, Gerlach, Rüdiger, additional, Gröschel, Klaus, additional, Große-Dresselhaus, Florian, additional, Günther, Albrecht, additional, Haase, Claus G, additional, Haensch, Carl-Albrecht, additional, Harloff, Andreas, additional, Heckmann, Joseph G, additional, Held, Valentin, additional, Hieber, Maren, additional, Kauert, Andreas, additional, Kern, Rolf, additional, Kerz, Thomas, additional, Köhrmann, Martin, additional, Kraft, Peter, additional, Kühnlein, Peter, additional, Latta, Jan, additional, Leinisch, Elke, additional, Lenz, Arne, additional, Leithner, Christoph, additional, Neumann-Haefelin, Tobias, additional, Mäurer, Mathias, additional, Müllges, Wolfgang, additional, Nolte, Christian H, additional, Obermann, Mark, additional, Partowi, Someieh, additional, Patzschke, Peer, additional, Poli, Sven, additional, Pulkowski, Ulrich, additional, Purrucker, Jan, additional, Rehfeldt, Torsten, additional, Ringleb, Peter A, additional, Röther, Joachim, additional, Rossi, Raluca, additional, El-Sabassy, Hazem, additional, Sauer, Oliver, additional, Schackert, Gabriele, additional, Schäfer, Niklas, additional, Schellinger, Peter D, additional, Schneider, Andreas, additional, Schuppner, Ramona, additional, Schwab, Stefan, additional, Schwarte, Olav, additional, Seitz, Rüdiger J, additional, Senger, Sebastian, additional, Shah, Yogesh P, additional, Sindern, Eckhart, additional, Sparenberg, Paul, additional, Steiner, Thorsten, additional, Szabo, Kristina, additional, Urbanek, Christian, additional, Sarnowksi, Bettina von, additional, Weissenborn, Karin, additional, Wienecke, Peter, additional, Witt, Karsten, additional, Wruck, Robert, additional, and Wunderlich, Silke, additional

Published
2020
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44. Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral Hemorrhage

Author

Kuramatsu, Joji B., primary, Biffi, Alessandro, additional, Gerner, Stefan T., additional, Sembill, Jochen A., additional, Sprügel, Maximilian I., additional, Leasure, Audrey, additional, Sansing, Lauren, additional, Matouk, Charles, additional, Falcone, Guido J., additional, Endres, Matthias, additional, Haeusler, Karl Georg, additional, Sobesky, Jan, additional, Schurig, Johannes, additional, Zweynert, Sarah, additional, Bauer, Miriam, additional, Vajkoczy, Peter, additional, Ringleb, Peter A., additional, Purrucker, Jan, additional, Rizos, Timolaos, additional, Volkmann, Jens, additional, Müllges, Wolfgang, additional, Kraft, Peter, additional, Schubert, Anna-Lena, additional, Erbguth, Frank, additional, Nueckel, Martin, additional, Schellinger, Peter D., additional, Glahn, Jörg, additional, Knappe, Ulrich J., additional, Fink, Gereon R., additional, Dohmen, Christian, additional, Stetefeld, Henning, additional, Fisse, Anna Lena, additional, Minnerup, Jens, additional, Hagemann, Georg, additional, Rakers, Florian, additional, Reichmann, Heinz, additional, Schneider, Hauke, additional, Rahmig, Jan, additional, Ludolph, Albert Christian, additional, Stösser, Sebastian, additional, Neugebauer, Hermann, additional, Röther, Joachim, additional, Michels, Peter, additional, Schwarz, Michael, additional, Reimann, Gernot, additional, Bäzner, Hansjörg, additional, Schwert, Henning, additional, Claßen, Joseph, additional, Michalski, Dominik, additional, Grau, Armin, additional, Palm, Frederick, additional, Urbanek, Christian, additional, Wöhrle, Johannes C., additional, Alshammari, Fahid, additional, Horn, Markus, additional, Bahner, Dirk, additional, Witte, Otto W., additional, Günther, Albrecht, additional, Hamann, Gerhard F., additional, Hagen, Manuel, additional, Roeder, Sebastian S., additional, Lücking, Hannes, additional, Dörfler, Arnd, additional, Testai, Fernando D., additional, Woo, Daniel, additional, Schwab, Stefan, additional, Sheth, Kevin N., additional, and Huttner, Hagen B., additional

Published
2019
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48. Diabetes severely affects attentional performance after coronary artery bypass grafting

Author

Krannich Jens-Holger, Tobias Therese, Broscheit Jens, Leyh Rainer, and Müllges Wolfgang

Subjects
Diabetes, Coronary artery bypass graft, Cognitive, Attentional performance, Surgery, RD1-811, Anesthesiology, RD78.3-87.3
Abstract

Abstract Background Diabetes is a risk factor for (micro) vascular damage of the brain, too. Therefore cognitive performance after coronary artery bypass grafting may be hypothesized worse in diabetics. To avoid observational errors a reliable tool for testing attentional performance was used. We evaluated whether diabetes mellitus disposes to distinct cognitive dysfunction after coronary artery bypass grafting (CABG). Methods Three aspects in attentional performance were prospectively tested with three different tests (alertness: composed of un-cued and cued reaction, divided attention, and selective attention) by a computerized tool one day before and seven days after CABG in a highly selected cohort of 30 males, 10 of whom had diabetes. Statistical comparisons were done with analysis of variance for repeated measurements and Fisher's LSD. Results Prior to CABG there was no statistically meaningful difference between diabetics and non-diabetics. Postoperatively, diabetic patients performed significantly worse than non-diabetics in tests for un-cued (p=0.01) and cued alertness (p=0.03). Test performance in divided attention was worse after CABG but independent of diabetes status. Selective attention was neither affected by diabetes status nor by CABG itself. Conclusions Diabetes may have an impact on cognitive performance after CABG. More severe deficits in alertness may point to underlying microvascular disease.

Published
2012
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50. Geriatrische Intensivmedizin

Author

Michels, Guido, primary, Sieber, Cornel C., additional, Marx, Gernot, additional, Roller-Wirnsberger, Regina, additional, Joannidis, Michael, additional, Müller-Werdan, Ursula, additional, Müllges, Wolfgang, additional, Gahn, Georg, additional, Pfister, Roman, additional, Thürmann, Petra A., additional, Wirth, Rainer, additional, Fresenborg, Jana, additional, Kuntz, Ludwig, additional, Simon, Steffen T., additional, Janssens, Uwe, additional, and Heppner, Hans Jürgen, additional

Published
2019
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